Primary Site >> Colorectal Cancer

Gene >> RARA

Journal: J Biol Chem. 1994 Jan 14;269(2):890-902.
Title: The directly repeated RG(G/T)TCA motifs of the rat and mouse cellular retinol-binding protein II genes are promiscuous binding sites for RAR, RXR, HNF-4, and ARP-1 homo- and heterodimers.
Author: Nakshatri, H|Chambon, P
PMID: 8288643
Journal: Exp Cell Res. 1997 Jun 15;233(2):321-9.
Title: Retinoids differentially regulate the proliferation of colon cancer cell lines.
Author: Stewart, L V|Thomas, M L
PMID: 9194494
Journal: Cell Growth Differ. 1998 Aug;9(8):629-37.
Title: Human retinoic acid (RA) 4-hydroxylase (CYP26) is highly specific for all-trans-RA and can be induced through RA receptors in human breast and colon carcinoma cells.
Author: Sonneveld, E|van den Brink, C E|van der Leede, B M|Schulkes, R K|Petkovich, M|van der Burg, B|van der Saag, P T
PMID: 9716180
Journal: Curr Biol. 1999 Dec 2;9(23):1415-8.
Title: Cross-regulation of beta-catenin-LEF/TCF and retinoid signaling pathways.
Author: Easwaran, V|Pishvaian, M|Salimuddin|Byers, S
PMID: 10607566
Journal: Biochem Pharmacol. 2000 Mar 1;59(5):485-96.
Title: Differential effects of retinoic acid on growth and apoptosis in human colon cancer cell lines associated with the induction of retinoic acid receptor beta.
Author: Lee, M O|Han, S Y|Jiang, S|Park, J H|Kim, S J
PMID: 10660115
Journal: Oncol Res. 2004;14(9):407-14.
Title: 4-[3,5-Bis(trimethylsilyl)benzamido] benzoic acid inhibits angiogenesis in colon cancer through reduced expression of vascular endothelial growth factor.
Author: Minagawa, Noritaka|Nakayama, Yoshifumi|Inoue, Yuzuru|Onitsuka, Koji|Katsuki, Takefumi|Tsurudome, Yosuke|Shibao, Kazunori|Hirata, Keiji|Sako, Tatsuhiko|Nagata, Naoki|Ohie, Shinji|Kohno, Kimitoshi|Itoh, Hideaki
PMID: 15490972
Journal: World J Gastroenterol. 2004 Dec 1;10(23):3441-54.
Title: Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis.
Author: Xu, Xiao-Li|Yu, Jian|Zhang, Hong-Yu|Sun, Meng-Hong|Gu, Jun|Du, Xiang|Shi, Da-Ren|Wang, Peng|Yang, Zhen-Hua|Zhu, Jing-De
PMID: 15526363
Journal: Endocr Rev. 2005 Dec;26(7):898-915. Epub 2005 Aug 26.
Title: Interaction of nuclear receptors with the Wnt/beta-catenin/Tcf signaling axis: Wnt you like to know?
Author: Mulholland, David J|Dedhar, Shoukat|Coetzee, Gerhard A|Nelson, Colleen C
PMID: 16126938
Journal: Cancer Res. 2005 Nov 1;65(21):9923-33.
Title: Retinol inhibits the growth of all-trans-retinoic acid-sensitive and all-trans-retinoic acid-resistant colon cancer cells through a retinoic acid receptor-independent mechanism.
Author: Park, Eun Young|Dillard, Alice|Williams, Elizabeth A|Wilder, Erik T|Pepper, M Reese|Lane, Michelle A
PMID: 16267017
Journal: Nutr Cancer. 2007;57(1):66-77.
Title: Retinol inhibits the invasion of retinoic acid-resistant colon cancer cells in vitro and decreases matrix metalloproteinase mRNA, protein, and activity levels.
Author: Park, Eun Young|Wilder, Erik T|Lane, Michelle A
PMID: 17516864
Journal: In Vivo. 2007 Mar-Apr;21(2):381-7.
Title: 4- [3,5-bis(trimethylsilyl)benzamido] benzoic acid (TAC-101) induced fas expression and activated caspase-3 and -8 in a DLD-1 colon cancer cell line.
Author: Inoue, Yuzuru|Nakayama, Yoshifumi|Sako, Tatsuhiko|Minagawa, Noritaka|Abe, Yukio|Nagato, Masaru|Kadowaki, Koji|Katsuki, Takefumi|Matsumoto, Kentaro|Tsurudome, Yosuke|Shibao, Kazunori|Hirata, Keiji|Nagata, Naoki
PMID: 17436592
Journal: Int J Colorectal Dis. 2008 Jun;23(6):569-80.
Title: Gene profiling of colonic serrated adenomas by using oligonucleotide microarray.
Author: Kim, Kyongrae|Park, Ungchae|Wang, Joonho|Lee, Jaedong|Park, Seunghwa|Kim, Sangyoon|Choi, Dongkug|Kim, Changil|Park, Jiyoung
PMID: 18305945
Journal: Anticancer Agents Med Chem. 2008 Jun;8(5):540-63.
Title: Bile acids and derivatives, their nuclear receptors FXR, PXR and ligands: role in health and disease and their therapeutic potential.
Author: Zimber, Amazia|Gespach, Christian
PMID: 18537536
Journal: Am J Physiol Gastrointest Liver Physiol. 2008 Nov;295(5):G996-G1003.
Title: beta-Klotho and FGF-15/19 inhibit the apical sodium-dependent bile acid transporter in enterocytes and cholangiocytes.
Author: Sinha, Jyoti|Chen, Frank|Miloh, Tamir|Burns, Robert C|Yu, Zhisheng|Shneider, Benjamin L
PMID: 18772362
Journal: Nutr Cancer. 2008;60(5):692-702.
Title: The short chain fatty acid butyrate induces promoter demethylation and reactivation of RARbeta2 in colon cancer cells.
Author: Spurling, Colleen C|Suhl, Joshua A|Boucher, Nathalie|Nelson, Craig E|Rosenberg, Daniel W|Giardina, Charles
PMID: 18791934
Journal: Exp Ther Med. 2011 May;2(3):491-497.
Title: Retinoid acid receptors in human colorectal cancer: An unexpected link with patient outcome.
Author: Perraud, Aurelie|Nouaille, Michelle|Akil, Hussein|Petit, Daniel|Labrousse, Francois|Jauberteau, Marie-Odile|Mathonnet, Muriel
PMID: 22977530
Journal: Biochem J. 2012 Aug 15;446(1):79-87.
Title: Revealing a natural marine product as a novel agonist for retinoic acid receptors with a unique binding mode and inhibitory effects on cancer cells.
Author: Wang, Shanshan|Wang, Zhao|Lin, Shengchen|Zheng, Weili|Wang, Rui|Jin, Shikai|Chen, Jinan|Jin, Lihua|Li, Yong
PMID: 22642567
Journal: Bioorg Med Chem. 2013 Feb 1;21(3):693-702.
Title: Synthesis and biological evaluation of halogenated curcumin analogs as potential nuclear receptor selective agonists.
Author: Batie, Shane|Lee, Jamie H|Jama, Rabia A|Browder, Drew O|Montano, Luis A|Huynh, Chanh C|Marcus, Lisa M|Tsosie, Dorian G|Mohammed, Zeynab|Trang, Vu|Marshall, Pamela A|Jurutka, Peter W|Wagner, Carl E
PMID: 23276449
Journal: World J Gastrointest Oncol. 2015 Oct 15;7(10):184-203.
Title: Role of retinoids in the prevention and treatment of colorectal cancer.
Author: Applegate, Catherine C|Lane, Michelle A
PMID: 26483874
Journal: Mol Cell Biol. 2017 Jul 14;37(15). pii: MCB.00012-17.
Title: Antagonistic Interactions between Extracellular Signal-Regulated Kinase Mitogen-Activated Protein Kinase and Retinoic Acid Receptor Signaling in Colorectal Cancer Cells.
Author: Imajo, Masamichi|Kondoh, Kunio|Yamamoto, Takuya|Nakayama, Kei|Nakajima-Koyama, May|Nishida, Eisuke
PMID: 28483913
Journal: Front Pharmacol. 2018 Feb 27;9:143.
Title: Multifactorial Modes of Action of Arsenic Trioxide in Cancer Cells as Analyzed by Classical and Network Pharmacology.
Author: Dawood, Mona|Hamdoun, Sami|Efferth, Thomas
PMID: 29535630