Primary Site >> Colorectal Cancer
Gene >> RARA
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Ref: The directly repeated RG(G/T)TCA motifs of the rat and mouse cellular retinol-binding protein II genes are promiscuous binding sites for RAR, RXR, HNF-4, and ARP-1 homo- and heterodimers. PMID: 8288643 |
Ref: Retinoids differentially regulate the proliferation of colon cancer cell lines. PMID: 9194494 |
Ref: Human retinoic acid (RA) 4-hydroxylase (CYP26) is highly specific for all-trans-RA and can be induced through RA receptors in human breast and colon carcinoma cells. PMID: 9716180 |
Ref: Cross-regulation of beta-catenin-LEF/TCF and retinoid signaling pathways. PMID: 10607566 |
Ref: Differential effects of retinoic acid on growth and apoptosis in human colon cancer cell lines associated with the induction of retinoic acid receptor beta. PMID: 10660115 |
Ref: 4-[3,5-Bis(trimethylsilyl)benzamido] benzoic acid inhibits angiogenesis in colon cancer through reduced expression of vascular endothelial growth factor. PMID: 15490972 Ref: Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis. PMID: 15526363 |
Ref: Interaction of nuclear receptors with the Wnt/beta-catenin/Tcf signaling axis: Wnt you like to know? PMID: 16126938 Ref: Retinol inhibits the growth of all-trans-retinoic acid-sensitive and all-trans-retinoic acid-resistant colon cancer cells through a retinoic acid receptor-independent mechanism. PMID: 16267017 |
Ref: 4- [3,5-bis(trimethylsilyl)benzamido] benzoic acid (TAC-101) induced fas expression and activated caspase-3 and -8 in a DLD-1 colon cancer cell line. PMID: 17436592 Ref: Retinol inhibits the invasion of retinoic acid-resistant colon cancer cells in vitro and decreases matrix metalloproteinase mRNA, protein, and activity levels. PMID: 17516864 |
Ref: Gene profiling of colonic serrated adenomas by using oligonucleotide microarray. PMID: 18305945 Ref: Bile acids and derivatives, their nuclear receptors FXR, PXR and ligands: role in health and disease and their therapeutic potential. PMID: 18537536 Ref: beta-Klotho and FGF-15/19 inhibit the apical sodium-dependent bile acid transporter in enterocytes and cholangiocytes. PMID: 18772362 Ref: The short chain fatty acid butyrate induces promoter demethylation and reactivation of RARbeta2 in colon cancer cells. PMID: 18791934 |
Ref: Retinoid acid receptors in human colorectal cancer: An unexpected link with patient outcome. PMID: 22977530 |
Ref: Revealing a natural marine product as a novel agonist for retinoic acid receptors with a unique binding mode and inhibitory effects on cancer cells. PMID: 22642567 |
Ref: Synthesis and biological evaluation of halogenated curcumin analogs as potential nuclear receptor selective agonists. PMID: 23276449 |
Ref: Role of retinoids in the prevention and treatment of colorectal cancer. PMID: 26483874 |
Ref: Antagonistic Interactions between Extracellular Signal-Regulated Kinase Mitogen-Activated Protein Kinase and Retinoic Acid Receptor Signaling in Colorectal Cancer Cells. PMID: 28483913 |
Ref: Multifactorial Modes of Action of Arsenic Trioxide in Cancer Cells as Analyzed by Classical and Network Pharmacology. PMID: 29535630 |