Primary Site >> Colorectal Cancer

Gene >> RAP1GAP

Journal: Carcinogenesis. 2005 Jul;26(7):1207-14.
Title: Transformation of immortalized colorectal crypt cells by microcystin involving constitutive activation of Akt and MAPK cascade.
Author: Zhu, Yongliang|Zhong, Xian|Zheng, Shu|Ge, Zhen|Du, Qin|Zhang, Suzhang
PMID: 15774489
Journal: Mol Cell Biol. 2010 Jul;30(13):3262-74.
Title: Downregulation of Rap1GAP in human tumor cells alters cell/matrix and cell/cell adhesion.
Author: Tsygankova, Oxana M|Ma, Changqing|Tang, Waixing|Korch, Christopher|Feldman, Michael D|Lv, Yu|Brose, Marcia S|Meinkoth, Judy L
PMID: 20439492
Journal: Cell Adh Migr. 2011 Jul-Aug;5(4):323-31. Epub 2011 Jul 1.
Title: Rap1GAP impairs cell-matrix adhesion in the absence of effects on cell-cell adhesion.
Author: Vuchak, Lisa A|Tsygankova, Oxana M|Meinkoth, Judy L
PMID: 21785277
Journal: J Biol Chem. 2013 Aug 23;288(34):24636-46.
Title: Tumor cell migration and invasion are enhanced by depletion of Rap1 GTPase-activating protein (Rap1GAP).
Author: Tsygankova, Oxana M|Wang, Hongbin|Meinkoth, Judy L
PMID: 23864657
Journal: Oncol Lett. 2018 May;15(5):7661-7668.
Title: The downregulation of Rap1 GTPase-activating protein is associated with a poor prognosis in colorectal cancer and may impact on tumor progression.
Author: Gao, Wei-Li|Ye, Guo-Chao|Liu, Li-Wei|Wei, Lu
PMID: 29725465