Primary Site >> Colorectal Cancer

Gene >> RAP1GAP

  • 2005
  • 2010
  • 2011
  • 2013
  • 2018
Ref: Transformation of immortalized colorectal crypt cells by microcystin involving constitutive activation of Akt and MAPK cascade.
PMID: 15774489
Ref: Downregulation of Rap1GAP in human tumor cells alters cell/matrix and cell/cell adhesion.
PMID: 20439492
Ref: Rap1GAP impairs cell-matrix adhesion in the absence of effects on cell-cell adhesion.
PMID: 21785277
Ref: Tumor cell migration and invasion are enhanced by depletion of Rap1 GTPase-activating protein (Rap1GAP).
PMID: 23864657
Ref: The downregulation of Rap1 GTPase-activating protein is associated with a poor prognosis in colorectal cancer and may impact on tumor progression.
PMID: 29725465