Primary Site >> Colorectal Cancer

Gene >> RAP1A

Journal: Cancer Res. 1992 Jan 15;52(2):285-9.
Title: Loss of heterozygosity at the human RAP1A/Krev-1 locus is a rare event in colorectal tumors.
Author: Young, J|Searle, J|Stitz, R|Cowen, A|Ward, M|Chenevix-French, G
PMID: 1345809
Journal: Int J Oncol. 1993 Aug;3(2):177-83.
Title: Chromosomal alterations in permanently differentiated ht29 colon-carcinoma cells induced with sodium-butyrate.
Author: Kondoh, N|Schweinfest, C|Papas, T
PMID: 21573345
Journal: Carcinogenesis. 2005 Jul;26(7):1207-14.
Title: Transformation of immortalized colorectal crypt cells by microcystin involving constitutive activation of Akt and MAPK cascade.
Author: Zhu, Yongliang|Zhong, Xian|Zheng, Shu|Ge, Zhen|Du, Qin|Zhang, Suzhang
PMID: 15774489
Journal: J Cell Physiol. 2007 Mar;210(3):740-9.
Title: Oncogenic KRAS provides a uniquely powerful and variable oncogenic contribution among RAS family members in the colonic epithelium.
Author: Keller, Jeffrey W|Franklin, Jeffrey L|Graves-Deal, Ramona|Friedman, David B|Whitwell, Corbin W|Coffey, Robert J
PMID: 17133351
Journal: Int J Oncol. 2011 Jun;38(6):1575-7.
Title: Frequent somatic demethylation of RAPGEF1/C3G intronic sequences in gastrointestinal and gynecological cancer.
Author: Samuelsson, Johanna|Alonso, Sergio|Ruiz-Larroya, Tatiana|Cheung, Tak Hong|Wong, Yick Fu|Perucho, Manuel
PMID: 21399874
Journal: Cell Adh Migr. 2011 Jul-Aug;5(4):323-31. Epub 2011 Jul 1.
Title: Rap1GAP impairs cell-matrix adhesion in the absence of effects on cell-cell adhesion.
Author: Vuchak, Lisa A|Tsygankova, Oxana M|Meinkoth, Judy L
PMID: 21785277
Journal: Biochem Biophys Res Commun. 2013 Jan 4;430(1):196-201.
Title: PRL-3 activates NF-kappaB signaling pathway by interacting with RAP1.
Author: Lian, Shenyi|Meng, Lin|Liu, Caiyun|Xing, Xiaofang|Song, Qian|Dong, Bin|Han, Yong|Yang, Yongyong|Peng, Lirong|Qu, Like|Shou, Chengchao
PMID: 23178297
Journal: J Egypt Natl Canc Inst. 2013 Mar;25(1):51-6.
Title: Immunohistochemical assay for detection of K-ras protein expression in metastatic colorectal cancer.
Author: Elsabah, Mahmoud Tag|Adel, Iman
PMID: 23499207
Journal: Sci Rep. 2015 Jun 22;5:11541.
Title: Voltage-gated Na+ Channel Activity Increases Colon Cancer Transcriptional Activity and Invasion Via Persistent MAPK Signaling.
Author: House, Carrie D|Wang, Bi-Dar|Ceniccola, Kristin|Williams, Russell|Simaan, May|Olender, Jacqueline|Patel, Vyomesh|Baptista-Hon, Daniel T|Annunziata, Christina M|Gutkind, J Silvio|Hales, Tim G|Lee, Norman H
PMID: 26096612
Journal: Nucleic Acids Res. 2017 Jun 20;45(11):6546-6571.
Title: PRL-3 promotes telomere deprotection and chromosomal instability.
Author: Lian, Shenyi|Meng, Lin|Yang, Yongyong|Ma, Ting|Xing, Xiaofang|Feng, Qin|Song, Qian|Liu, Caiyun|Tian, Zhihua|Qu, Like|Shou, Chengchao
PMID: 28482095
Journal: J Cancer Res Clin Oncol. 2018 Feb;144(2):295-308.
Title: The function of BTG3 in colorectal cancer cells and its possible signaling pathway.
Author: Lv, Chi|Wang, Heling|Tong, Yuxin|Yin, Hongzhuan|Wang, Dalu|Yan, Zhaopeng|Liang, Yichao|Wu, Di|Su, Qi
PMID: 29270670
Journal: Oncol Lett. 2018 May;15(5):7661-7668.
Title: The downregulation of Rap1 GTPase-activating protein is associated with a poor prognosis in colorectal cancer and may impact on tumor progression.
Author: Gao, Wei-Li|Ye, Guo-Chao|Liu, Li-Wei|Wei, Lu
PMID: 29725465
Journal: J Exp Clin Cancer Res. 2018 Jul 31;37(1):178.
Title: High expression of Ras-related protein 1A promotes an aggressive phenotype in colorectal cancer via PTEN/FOXO3/CCND1 pathway.
Author: Liu, Liguo|Yan, Xuebing|Wu, Dapeng|Yang, Yi|Li, Mengcheng|Su, Yang|Yang, Wenchao|Shan, Zezhi|Gao, Yuping|Jin, Zhiming
PMID: 30064475