Primary Site >> Colorectal Cancer
Gene >> RAP1A
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Ref: Loss of heterozygosity at the human RAP1A/Krev-1 locus is a rare event in colorectal tumors. PMID: 1345809 |
Ref: Chromosomal alterations in permanently differentiated ht29 colon-carcinoma cells induced with sodium-butyrate. PMID: 21573345 |
Ref: Transformation of immortalized colorectal crypt cells by microcystin involving constitutive activation of Akt and MAPK cascade. PMID: 15774489 |
Ref: Oncogenic KRAS provides a uniquely powerful and variable oncogenic contribution among RAS family members in the colonic epithelium. PMID: 17133351 |
Ref: Frequent somatic demethylation of RAPGEF1/C3G intronic sequences in gastrointestinal and gynecological cancer. PMID: 21399874 Ref: Rap1GAP impairs cell-matrix adhesion in the absence of effects on cell-cell adhesion. PMID: 21785277 |
Ref: PRL-3 activates NF-kappaB signaling pathway by interacting with RAP1. PMID: 23178297 Ref: Immunohistochemical assay for detection of K-ras protein expression in metastatic colorectal cancer. PMID: 23499207 |
Ref: Voltage-gated Na+ Channel Activity Increases Colon Cancer Transcriptional Activity and Invasion Via Persistent MAPK Signaling. PMID: 26096612 |
Ref: PRL-3 promotes telomere deprotection and chromosomal instability. PMID: 28482095 |
Ref: The function of BTG3 in colorectal cancer cells and its possible signaling pathway. PMID: 29270670 Ref: The downregulation of Rap1 GTPase-activating protein is associated with a poor prognosis in colorectal cancer and may impact on tumor progression. PMID: 29725465 Ref: High expression of Ras-related protein 1A promotes an aggressive phenotype in colorectal cancer via PTEN/FOXO3/CCND1 pathway. PMID: 30064475 |