Literatures

Primary Site >> Colorectal Cancer

Gene >> RAF1

1.
Journal:	Princess Takamatsu Symp. 1986;17:75-84.
Title:	Activation of rat and human c-raf(-1) by rearrangement.
Author:	Nagao, M\|Ishikawa, F\|Tahira, T\|Ochiai, M\|Sugimura, T
PMID:	3332022

2.
Journal:	Nucleic Acids Res. 1987 Jun 25;15(12):4809-20.
Title:	Activation of human c-raf-1 by replacing the N-terminal region with different sequences.
Author:	Tahira, T\|Ochiai, M\|Hayashi, K\|Nagao, M\|Sugimura, T
PMID:	2955285

3.
Journal:	Cancer. 1993 Feb 1;71(3):672-6.
Title:	Multiple polyps of esophagus, stomach, colon, and rectum accompanying rectal cancer in a patient with constitutional chromosomal inversion.
Author:	Sasajima, K\|Yamanaka, Y\|Inokuchi, K\|Takizawa, T\|Ujihara, Y\|Ide, Y\|Onda, M\|Takubo, K
PMID:	8431846

4.
Journal:	Dig Dis Sci. 1996 Jun;41(6):1069-75.
Title:	Raf-1 kinase, epidermal growth factor receptors, and mutant Ras proteins in colonic carcinomas.
Author:	Eggstein, S\|Manthey, G\|Hirsch, T\|Baas, F\|Specht, B U\|Farthmann, E H
PMID:	8654136

5.
Journal:	Cancer Res. 1996 Jun 15;56(12):2872-6.
Title:	Suppression of a human colon cancer cell line by introduction of an exogenous NF1 gene.
Author:	Li, Y\|White, R
PMID:	8665528

6.
Journal:	Cytometry. 1997 Sep 1;29(1):1-27.
Title:	Common patterns of genetic evolution in human solid tumors.
Author:	Shackney, S E\|Shankey, T V
PMID:	9298807

7.
Journal:	Oncogene. 1998 Apr 9;16(14):1899-902.
Title:	Abrogation of c-Raf expression induces apoptosis in tumor cells.
Author:	Lau, Q C\|Brusselbach, S\|Muller, R
PMID:	9583688

8.
Journal:	Br J Cancer. 2002 Sep 23;87(7):783-9.
Title:	Use of radiolabelled choline as a pharmacodynamic marker for the signal transduction inhibitor geldanamycin.
Author:	Liu, D\|Hutchinson, O C\|Osman, S\|Price, P\|Workman, P\|Aboagye, E O
PMID:	12232764

9.
Journal:	Biochim Biophys Acta. 2003 Jun 5;1653(1):25-40.
Title:	Raf proteins and cancer: B-Raf is identified as a mutational target.
Author:	Mercer, Kathryn E\|Pritchard, Catrin A
PMID:	12781369

10.
Journal:	J Cell Sci. 2003 Dec 15;116(Pt 24):4957-63.
Title:	Elevated ERK-MAP kinase activity protects the FOS family member FRA-1 against proteasomal degradation in colon carcinoma cells.
Author:	Vial, Emmanuel\|Marshall, Christopher J
PMID:	14625389

11.
Journal:	Carcinogenesis. 2004 Apr;25(4):527-33. Epub 2003 Dec 19.
Title:	Mutation analysis of the BRAF, ARAF and RAF-1 genes in human colorectal adenocarcinomas.
Author:	Fransen, Karin\|Klintenas, Maria\|Osterstrom, Anna\|Dimberg, Jan\|Monstein, Hans-Jurg\|Soderkvist, Peter
PMID:	14688025

12.
Journal:	Postepy Hig Med Dosw (Online). 2004;58:428-37.
Title:	[Complex forms of immune insufficiency to some cytokines (TNF-alpha, interferons) in colorectal cancers as exemplified by the COLO 205 cell line. Mechanism of resistance with special reference to signaling proteins and cytokines].
Author:	Pajak, Beata\|Orzechowski, Arkadiusz
PMID:	15577750

13.
Journal:	Oncogene. 2004 Mar 11;23(10):1885-95.
Title:	Regulation of phorbol ester-mediated TRAF1 induction in human colon cancer cells through a PKC/RAF/ERK/NF-kappaB-dependent pathway.
Author:	Wang, Xiaofu\|Wang, Qingding\|Hu, Wanqin\|Evers, B Mark
PMID:	14981539

14.
Journal:	J Nutr. 2004 Feb;134(2):483-6.
Title:	Ursodeoxycholic acid (UDCA) can inhibit deoxycholic acid (DCA)-induced apoptosis via modulation of EGFR/Raf-1/ERK signaling in human colon cancer cells.
Author:	Im, Eunok\|Martinez, Jesse D
PMID:	14747693

15.
Journal:	Cancer Biol Ther. 2005 Oct;4(10):1159-67. Epub 2005 Oct 23.
Title:	Chemotherapy regimen GOLF induces apoptosis in colon cancer cells through multi-chaperone complex inactivation and increased Raf-1 ubiquitin-dependent degradation.
Author:	Caraglia, Michele\|Marra, Monica\|Budillon, Alfredo\|Meo, Giuseppina\|Ricciardiello, Filippo\|Bismuto, Ettore\|Brachelente, Giovanni\|Francini, Guido\|Giordano, Antonio\|Correale, Pierpaolo\|Abbruzzese, Alberto
PMID:	16294035

16.
Journal:	J Cell Sci. 2006 Mar 1;119(Pt 5):819-27. Epub 2006 Feb 14.
Title:	APC inhibits ERK pathway activation and cellular proliferation induced by RAS.
Author:	Park, Ki-Sook\|Jeon, Soung Hoo\|Kim, Sung-Eun\|Bahk, Young-Yil\|Holmen, Sheri L\|Williams, Bart O\|Chung, Kwang-Chul\|Surh, Young-Joon\|Choi, Kang-Yell
PMID:	16478791

17.
Journal:	J Mol Med (Berl). 2007 Mar;85(3):293-304. Epub 2006 Dec 2.
Title:	Array CGH identifies distinct DNA copy number profiles of oncogenes and tumor suppressor genes in chromosomal- and microsatellite-unstable sporadic colorectal carcinomas.
Author:	Lassmann, Silke\|Weis, Roland\|Makowiec, Frank\|Roth, Jasmine\|Danciu, Mihai\|Hopt, Ulrich\|Werner, Martin
PMID:	17143621

18.
Journal:	Mol Cancer Ther. 2007 Apr;6(4):1198-211.
Title:	Inhibition of the heat shock protein 90 molecular chaperone in vitro and in vivo by novel, synthetic, potent resorcinylic pyrazole/isoxazole amide analogues.
Author:	Sharp, Swee Y\|Prodromou, Chrisostomos\|Boxall, Kathy\|Powers, Marissa V\|Holmes, Joanna L\|Box, Gary\|Matthews, Thomas P\|Cheung, Kwai-Ming J\|Kalusa, Andrew\|James, Karen\|Hayes, Angela\|Hardcastle, Anthea\|Dymock, Brian\|Brough, Paul A\|Barril, Xavier\|Cansfield, Jul
PMID:	17431102

19.
Journal:	Genes Chromosomes Cancer. 2008 Mar;47(3):253-9.
Title:	SOS1 mutations are rare in human malignancies: implications for Noonan Syndrome patients.
Author:	Swanson, Kenneth D\|Winter, Jordan M\|Reis, Marcelo\|Bentires-Alj, Mohamed\|Greulich, Heidi\|Grewal, Rupinder\|Hruban, Ralph H\|Yeo, Charles J\|Yassin, Yosuf\|Iartchouk, Oleg\|Montgomery, Kate\|Whitman, Susan P\|Caligiuri, Michael A\|Loh, Mignon L\|Gilliland, D Gary\|Lo
PMID:	18064648

20.
Journal:	Mol Cancer Ther. 2008 Apr;7(4):915-22.
Title:	Effects of protein kinase C modulation by PEP005, a novel ingenol angelate, on mitogen-activated protein kinase and phosphatidylinositol 3-kinase signaling in cancer cells.
Author:	Serova, Maria\|Ghoul, Aida\|Benhadji, Karim A\|Faivre, Sandrine\|Le Tourneau, Christophe\|Cvitkovic, Esteban\|Lokiec, Francois\|Lord, Janet\|Ogbourne, Steven M\|Calvo, Fabien\|Raymond, Eric
PMID:	18413805

21.
Journal:	Oncogene. 2009 Jan 15;28(2):157-69.
Title:	Silencing the cochaperone CDC37 destabilizes kinase clients and sensitizes cancer cells to HSP90 inhibitors.
Author:	Smith, J R\|Clarke, P A\|de Billy, E\|Workman, P
PMID:	18931700

22.
Journal:	PLoS One. 2009 May 27;4(5):e5717.
Title:	Combined targeting of BRAF and CRAF or BRAF and PI3K effector pathways is required for efficacy in NRAS mutant tumors.
Author:	Jaiswal, Bijay S\|Janakiraman, Vasantharajan\|Kljavin, Noelyn M\|Eastham-Anderson, Jeffrey\|Cupp, James E\|Liang, Yuxin\|Davis, David P\|Hoeflich, Klaus P\|Seshagiri, Somasekar
PMID:	19492075

23.
Journal:	Sheng Li Ke Xue Jin Zhan. 2009 Jul;40(3):214-8.
Title:	[Phosphatidylethanolamine-binding protein (PEBP) in basic and clinical study].
Author:	Li, Fang-Fang\|Song, Shi-Jun\|Zhang, Ruo-Nan
PMID:	19803424

24.
Journal:	PLoS Comput Biol. 2009 Dec;5(12):e1000601.
Title:	Human cancer protein-protein interaction network: a structural perspective.
Author:	Kar, Gozde\|Gursoy, Attila\|Keskin, Ozlem
PMID:	20011507

25.
Journal:	Gastroenterology. 2010 Jun;138(7):2357-67.
Title:	Oncogenic K-Ras turns death receptors into metastasis-promoting receptors in human and mouse colorectal cancer cells.
Author:	Hoogwater, Frederik J H\|Nijkamp, Maarten W\|Smakman, Niels\|Steller, Ernst J A\|Emmink, Benjamin L\|Westendorp, B Florien\|Raats, Danielle A E\|Sprick, Martin R\|Schaefer, Uta\|Van Houdt, Winan J\|De Bruijn, Menno T\|Schackmann, Ron C J\|Derksen, Patrick W B\|Medema,
PMID:	20188103

26.
Journal:	PLoS One. 2012;7(8):e40392.
Title:	Genomic aberrations in an African American colorectal cancer cohort reveals a MSI-specific profile and chromosome X amplification in male patients.
Author:	Brim, Hassan\|Lee, Edward\|Abu-Asab, Mones S\|Chaouchi, Mohamed\|Razjouyan, Hadi\|Namin, Hassanzadeh\|Goel, Ajay\|Schaffer, Alejandro A\|Ashktorab, Hassan
PMID:	22879877

27.
Journal:	Carcinogenesis. 2012 Dec;33(12):2398-408.
Title:	MAP kinase genes and colon and rectal cancer.
Author:	Slattery, Martha L\|Lundgreen, Abbie\|Wolff, Roger K
PMID:	23027623

28.
Journal:	PLoS One. 2012;7(9):e44642.
Title:	Co-crystalization and in vitro biological characterization of 5-aryl-4-(5-substituted-2-4-dihydroxyphenyl)-1,2,3-thiadiazole Hsp90 inhibitors.
Author:	Sharp, Swee Y\|Roe, S Mark\|Kazlauskas, Egidijus\|Cikotiene, Inga\|Workman, Paul\|Matulis, Daumantas\|Prodromou, Chrisostomos
PMID:	22984537

29.
Journal:	Cancer Genet. 2012 Oct;205(10):501-7.
Title:	Association of polymorphisms in microRNA-binding sites and colorectal cancer in an Iranian population.
Author:	Azimzadeh, Pedram\|Romani, Sara\|Mohebbi, Seyed Reza\|Mahmoudi, Touraj\|Vahedi, Mohsen\|Fatemi, Seyed Reza\|Zali, Narges\|Zali, Mohammad Reza
PMID:	22939228

30.
Journal:	Int J Oncol. 2012 Nov;41(5):1855-62.
Title:	Combination therapy targeting Raf-1 and MEK causes apoptosis of HCT116 colon cancer cells.
Author:	Subramanian, Romesh R\|Yamakawa, Akio
PMID:	22922669

31.
Journal:	Expert Opin Investig Drugs. 2012 Jun;21(6):879-89.
Title:	Regorafenib for cancer.
Author:	Strumberg, Dirk\|Schultheis, Beate
PMID:	22577890

32.
Journal:	Cancer Discov. 2012 Mar;2(3):227-35.
Title:	EGFR-mediated re-activation of MAPK signaling contributes to insensitivity of BRAF mutant colorectal cancers to RAF inhibition with vemurafenib.
Author:	Corcoran, Ryan B\|Ebi, Hiromichi\|Turke, Alexa B\|Coffee, Erin M\|Nishino, Michiya\|Cogdill, Alexandria P\|Brown, Ronald D\|Della Pelle, Patricia\|Dias-Santagata, Dora\|Hung, Kenneth E\|Flaherty, Keith T\|Piris, Adriano\|Wargo, Jennifer A\|Settleman, Jeffrey\|Mino-Kenu
PMID:	22448344

33.
Journal:	J Cell Mol Med. 2013 Oct;17(10):1316-24.
Title:	Brucine suppresses colon cancer cells growth via mediating KDR signalling pathway.
Author:	Luo, Wenjuan\|Wang, Xiaoli\|Zheng, Lei\|Zhan, Yingzhuan\|Zhang, Dongdong\|Zhang, Jie\|Zhang, Yanmin
PMID:	23905676

34.
Journal:	Int J Cancer. 2013 Nov;133(9):2089-101.
Title:	Antitumor activity of pimasertib, a selective MEK 1/2 inhibitor, in combination with PI3K/mTOR inhibitors or with multi-targeted kinase inhibitors in pimasertib-resistant human lung and colorectal cancer cells.
Author:	Martinelli, Erika\|Troiani, Teresa\|D'Aiuto, Elena\|Morgillo, Floriana\|Vitagliano, Donata\|Capasso, Anna\|Costantino, Sarah\|Ciuffreda, Loreta Pia\|Merolla, Francesco\|Vecchione, Loredana\|De Vriendt, Veerle\|Tejpar, Sabine\|Nappi, Anna\|Sforza, Vincenzo\|Martini, Giu
PMID:	23629727

35.
Journal:	Nutr Cancer. 2013;65(5):729-38.
Title:	Dietary influence on MAPK-signaling pathways and risk of colon and rectal cancer.
Author:	Slattery, Martha L\|Lundgreen, Abbie\|Wolff, Roger K
PMID:	23859041

36.
Journal:	PLoS One. 2013 Jul 3;8(7):e67583.
Title:	Dabrafenib; preclinical characterization, increased efficacy when combined with trametinib, while BRAF/MEK tool combination reduced skin lesions.
Author:	King, Alastair J\|Arnone, Marc R\|Bleam, Maureen R\|Moss, Katherine G\|Yang, Jingsong\|Fedorowicz, Kelly E\|Smitheman, Kimberly N\|Erhardt, Joseph A\|Hughes-Earle, Angela\|Kane-Carson, Laurie S\|Sinnamon, Robert H\|Qi, Hongwei\|Rheault, Tara R\|Uehling, David E\|Laquer
PMID:	23844038

37.
Journal:	PLoS Genet. 2013 Apr;9(4):e1003464.
Title:	Breakpoint analysis of transcriptional and genomic profiles uncovers novel gene fusions spanning multiple human cancer types.
Author:	Giacomini, Craig P\|Sun, Steven\|Varma, Sushama\|Shain, A Hunter\|Giacomini, Marilyn M\|Balagtas, Jay\|Sweeney, Robert T\|Lai, Everett\|Del Vecchio, Catherine A\|Forster, Andrew D\|Clarke, Nicole\|Montgomery, Kelli D\|Zhu, Shirley\|Wong, Albert J\|van de Rijn, Matt\|Wes
PMID:	23637631

38.
Journal:	Expert Opin Med Diagn. 2013 Mar;7(2):137-46.
Title:	Novel biomarkers for the prediction of metastasis in colorectal cancer.
Author:	Zlobec, Inti
PMID:	23530884

39.
Journal:	Expert Opin Investig Drugs. 2013 Jun;22(6):739-49.
Title:	Phase I/II RAF kinase inhibitors in cancer therapy.
Author:	Turajlic, Samra\|Ali, Zohra\|Yousaf, Nadia\|Larkin, James
PMID:	23642225

40.
Journal:	Gastroenterology. 2014 May;146(5):1301-12.e1-10.
Title:	PHLPP is a negative regulator of RAF1, which reduces colorectal cancer cell motility and prevents tumor progression in mice.
Author:	Li, Xin\|Stevens, Payton D\|Liu, Jianyu\|Yang, Haihua\|Wang, Wei\|Wang, Chi\|Zeng, Zheng\|Schmidt, Micheal D\|Yang, Mike\|Lee, Eun Y\|Gao, Tianyan
PMID:	24530606

41.
Journal:	Expert Opin Drug Discov. 2014 Sep;9(9):1087-101.
Title:	The preclinical development of regorafenib for the treatment of colorectal cancer.
Author:	Miura, Koh\|Satoh, Masayuki\|Kinouchi, Makoto\|Yamamoto, Kuniharu\|Hasegawa, Yasuhiro\|Philchenkov, Alex\|Kakugawa, Yoichiro\|Fujiya, Tsuneaki
PMID:	24896071

42.
Journal:	Cancer Discov. 2014 Oct;4(10):1182-1197.
Title:	Development of siRNA payloads to target KRAS-mutant cancer.
Author:	Yuan, Tina L\|Fellmann, Christof\|Lee, Chih-Shia\|Ritchie, Cayde D\|Thapar, Vishal\|Lee, Liam C\|Hsu, Dennis J\|Grace, Danielle\|Carver, Joseph O\|Zuber, Johannes\|Luo, Ji\|McCormick, Frank\|Lowe, Scott W
PMID:	25100204

43.
Journal:	PLoS One. 2014 Dec 26;9(12):e116169.
Title:	The influence of the CHIEF pathway on colorectal cancer-specific mortality.
Author:	Slattery, Martha L\|Lundgreen, Abbie
PMID:	25541970

44.
Journal:	Oncogene. 2015 Jan 2;34(1):15-26.
Title:	Restricting direct interaction of CDC37 with HSP90 does not compromise chaperoning of client proteins.
Author:	Smith, J R\|de Billy, E\|Hobbs, S\|Powers, M\|Prodromou, C\|Pearl, L\|Clarke, P A\|Workman, P
PMID:	24292678

45.
Journal:	Tumour Biol. 2015 Feb;36(2):1313-21.
Title:	MicroRNA-455 inhibits proliferation and invasion of colorectal cancer by targeting RAF proto-oncogene serine/threonine-protein kinase.
Author:	Chai, Jie\|Wang, Shan\|Han, Dali\|Dong, Wei\|Xie, Chao\|Guo, Hongliang
PMID:	25355599

46.
Journal:	Am J Pathol. 2015 Apr;185(4):1135-44.
Title:	Methionine adenosyltransferase 2B-GIT1 complex serves as a scaffold to regulate Ras/Raf/MEK1/2 activity in human liver and colon cancer cells.
Author:	Peng, Hui\|Li, Tony W H\|Yang, Heping\|Moyer, Mary P\|Mato, Jose M\|Lu, Shelly C
PMID:	25794709

47.
Journal:	Mar Drugs. 2015 Jun 5;13(6):3625-39.
Title:	Activation of RAF1 (c-RAF) by the Marine Alkaloid Lasonolide A Induces Rapid Premature Chromosome Condensation.
Author:	Josse, Rozenn\|Zhang, Yong-Wei\|Giroux, Valentin\|Ghosh, Arun K\|Luo, Ji\|Pommier, Yves
PMID:	26058013

48.
Journal:	Mol Cancer Ther. 2015 Dec;14(12):2700-11.
Title:	Combined Pan-RAF and MEK Inhibition Overcomes Multiple Resistance Mechanisms to Selective RAF Inhibitors.
Author:	Whittaker, Steven R\|Cowley, Glenn S\|Wagner, Steve\|Luo, Flora\|Root, David E\|Garraway, Levi A
PMID:	26351322

49.
Journal:	J Enzyme Inhib Med Chem. 2016;31(sup2):111-122.
Title:	Design, synthesis, and in vitro antiproliferative and kinase inhibitory effects of pyrimidinylpyrazole derivatives terminating with arylsulfonamido or cyclic sulfamide substituents.
Author:	Gamal El-Din, Mahmoud M\|El-Gamal, Mohammed I\|Abdel-Maksoud, Mohammed S\|Yoo, Kyung Ho\|Baek, Daejin\|Choi, Jungseung\|Lee, Huiseong\|Oh, Chang-Hyun
PMID:	27255180

50.
Journal:	PLoS One. 2016 Jul 6;11(7):e0156971.
Title:	Human Blood Autoantibodies in the Detection of Colorectal Cancer.
Author:	Negm, Ola H\|Hamed, Mohamed R\|Schoen, Robert E\|Whelan, Richard L\|Steele, Robert J\|Scholefield, John\|Dilnot, Elizabeth M\|Shantha Kumara, H M C\|Robertson, John F R\|Sewell, Herbert F
PMID:	27383396

51.
Journal:	Proteomics. 2016 May;16(10):1557-69.
Title:	Mechanistic study of the anti-cancer effect of Gynostemma pentaphyllum saponins in the Apc(Min/+) mouse model.
Author:	Tai, William Chi-Shing\|Wong, Wing-Yan\|Lee, Magnolia Muk-Lan\|Chan, Brandon Dow\|Lu, Cheng\|Hsiao, Wen-Luan Wendy
PMID:	26970558

52.
Journal:	Cell Cycle. 2016;15(4):506-18.
Title:	Tumor cells with KRAS or BRAF mutations or ERK5/MAPK7 amplification are not addicted to ERK5 activity for cell proliferation.
Author:	Lochhead, Pamela A\|Clark, Jonathan\|Wang, Lan-Zhen\|Gilmour, Lesley\|Squires, Matthew\|Gilley, Rebecca\|Foxton, Caroline\|Newell, David R\|Wedge, Stephen R\|Cook, Simon J
PMID:	26959608

53.
Journal:	FEBS Lett. 2016 Jun;590(11):1641-50.
Title:	IGF2BP2 promotes colorectal cancer cell proliferation and survival through interfering with RAF-1 degradation by miR-195.
Author:	Ye, Song\|Song, Wei\|Xu, Xiaogang\|Zhao, Xinyi\|Yang, Liu
PMID:	27153315

54.
Journal:	Br J Cancer. 2017 Jun 27;117(1):136-143.
Title:	Targeted sequencing-based analyses of candidate gene variants in ulcerative colitis-associated colorectal neoplasia.
Author:	Chakrabarty, Sanjiban\|Varghese, Vinay Koshy\|Sahu, Pranoy\|Jayaram, Pradyumna\|Shivakumar, Bhadravathi M\|Pai, Cannanore Ganesh\|Satyamoorthy, Kapaettu
PMID:	28524162

55.
Journal:	Life Sci. 2017 Aug 15;183:37-44.
Title:	Discovery of a novel pan-RAF inhibitor with potent anti-tumor activity in preclinical models of BRAF(V600E) mutant cancer.
Author:	Hong, Sung Pyo\|Ahn, Soon Kil
PMID:	28645859

56.
Journal:	Biochem Biophys Res Commun. 2017 Jul 15;489(1):14-20.
Title:	AKT is critically involved in the antagonism of BRAF inhibitor sorafenib against dabrafenib in colorectal cancer cells harboring both wild-type and mutant (V600E) BRAF genes.
Author:	Wang, Hongbin\|Quan, Haitian\|Lou, Liguang
PMID:	28536078

57.
Journal:	Org Biomol Chem. 2017 Apr 18;15(16):3455-3465.
Title:	Rational design, synthesis, and biological evaluation of Pan-Raf inhibitors to overcome resistance.
Author:	Wang, Lu\|Zhu, Gaoyuan\|Zhang, Qing\|Duan, Chunqi\|Zhang, Yanmin\|Zhang, Zhimin\|Zhou, Yujun\|Lu, Tao\|Tang, Weifang
PMID:	28368067

58.
Journal:	Clin Cancer Res. 2017 Jul 15;23(14):3918-3928.
Title:	Circular RNA ciRS-7-A Promising Prognostic Biomarker and a Potential Therapeutic Target in Colorectal Cancer.
Author:	Weng, Wenhao\|Wei, Qing\|Toden, Shusuke\|Yoshida, Kazuhiro\|Nagasaka, Takeshi\|Fujiwara, Toshiyoshi\|Cai, Sanjun\|Qin, Huanlong\|Ma, Yanlei\|Goel, Ajay
PMID:	28174233

59.
Journal:	Oncotarget. 2017 Feb 7;8(6):9251-9266.
Title:	LY3009120, a panRAF inhibitor, has significant anti-tumor activity in BRAF and KRAS mutant preclinical models of colorectal cancer.
Author:	Vakana, Eliza\|Pratt, Susan\|Blosser, Wayne\|Dowless, Michele\|Simpson, Nicholas\|Yuan, Xiu-Juan\|Jaken, Susan\|Manro, Jason\|Stephens, Jennifer\|Zhang, Youyan\|Huber, Lysiane\|Peng, Sheng-Bin\|Stancato, Louis F
PMID:	27999210

60.
Journal:	Gut. 2017 Jun;66(6):1106-1115.
Title:	Inhibition of RAF1 kinase activity restores apicobasal polarity and impairs tumour growth in human colorectal cancer.
Author:	Borovski, Tijana\|Vellinga, Thomas T\|Laoukili, Jamila\|Santo, Evan E\|Fatrai, Szabolcs\|van Schelven, Susanne\|Verheem, Andre\|Marvin, Dieuwke L\|Ubink, Inge\|Borel Rinkes, Inne H M\|Kranenburg, Onno
PMID:	27670374

61.
Journal:	Oncogene. 2017 Jan 19;36(3):423-428.
Title:	Inhibition of the CRAF/prohibitin interaction reverses CRAF-dependent resistance to vemurafenib.
Author:	Doudican, N A\|Orlow, S J
PMID:	27321184

62.
Journal:	Food Chem Toxicol. 2018 Feb;112:11-18.
Title:	Enhancement of colon carcinogenesis by the combination of indole-3 carbinol and synbiotics in hemin-fed rats.
Author:	de Moura, Nelci A\|Caetano, Brunno F R\|de Moraes, Leonardo N\|Carvalho, Robson F\|Rodrigues, Maria A M\|Barbisan, Luis F
PMID:	29269057

63.
Journal:	Medicine (Baltimore). 2018 Feb;97(7):e9738.
Title:	Identification of gene expression models for laryngeal squamous cell carcinoma using co-expression network analysis.
Author:	Yang, Chun-Wei\|Wang, Shu-Fang\|Yang, Xiang-Li\|Wang, Lin\|Niu, Lin\|Liu, Ji-Xiang
PMID:	29443735

64.
Journal:	Oncotarget. 2017 Dec 27;9(5):6086-6094.
Title:	Construction of key signal regulatory network in metastatic colorectal cancer.
Author:	Qi, Lu\|Ding, Yanqing
PMID:	29464057

65.
Journal:	Evid Based Complement Alternat Med. 2018 Feb 12;2018:6517034.
Title:	A Network Pharmacology Approach to Uncover the Multiple Mechanisms of Hedyotis diffusa Willd. on Colorectal Cancer.
Author:	Liu, Xinkui\|Wu, Jiarui\|Zhang, Dan\|Wang, Kaihuan\|Duan, Xiaojiao\|Zhang, Xiaomeng
PMID:	29619072

66.
Journal:	FASEB J. 2018 Aug 14:fj201800336R.
Title:	Nuclear localized Raf1 isoform alters DNA-dependent protein kinase activity and the DNA damage response.
Author:	Nixon, Benjamin R\|Sebag, Sara C\|Glennon, Michael S\|Hall, Eric J\|Kounlavong, Emily S\|Freeman, Michael L\|Becker, Jason R
PMID:	30106602

67.
Journal:	Cell Cycle. 2018 Nov 1.
Title:	Up-regulation of microRNA-497 inhibits the proliferation, migration and invasion but increases the apoptosis of multiple myeloma cells through the MAPK/ERK signaling pathway by targeting Raf-1.
Author:	Ye, Cheng-Yu\|Zheng, Cui-Ping\|Ying, Wei-Wei\|Weng, Shan-Shan
PMID:	30382763