Primary Site >> Colorectal Cancer
Gene >> RAD50
| 1. | |||||||||||
| Journal: | Oncogene. 1999 Jun 3;18(22):3422-6. | ||||||||||
| Title: | Mutations of a novel human RAD54 homologue, RAD54B, in primary cancer. | ||||||||||
| Author: | Hiramoto, T|Nakanishi, T|Sumiyoshi, T|Fukuda, T|Matsuura, S|Tauchi, H|Komatsu, K|Shibasaki, Y|Inui, H|Watatani, M|Yasutomi, M|Sumii, K|Kajiyama, G|Kamada, N|Miyagawa, K|Kamiya, K | ||||||||||
| PMID: | 10362364 | ||||||||||
| 2. | |||||||||||
| Journal: | Hum Mol Genet. 2001 Mar 1;10(5):513-8. | ||||||||||
| Title: | Evolution of instability at coding and non-coding repeat sequences in human MSI-H colorectal cancers. | ||||||||||
| Author: | Duval, A|Rolland, S|Compoint, A|Tubacher, E|Iacopetta, B|Thomas, G|Hamelin, R | ||||||||||
| PMID: | 11181575 | ||||||||||
| 3. | |||||||||||
| Journal: | Jpn J Cancer Res. 2001 Jun;92(6):587-91. | ||||||||||
| Title: | Frameshift mutations at mononucleotide repeats in RAD50 recombinational DNA repair gene in colorectal cancers with microsatellite instability. | ||||||||||
| Author: | Ikenoue, T|Togo, G|Nagai, K|Ijichi, H|Kato, J|Yamaji, Y|Okamoto, M|Kato, N|Kawabe, T|Tanaka, A|Matsumura, M|Shiratori, Y|Omata, M | ||||||||||
| PMID: | 11429044 | ||||||||||
| 4. | |||||||||||
| Journal: | Oncogene. 2004 Apr 8;23(15):2640-7. | ||||||||||
| Title: | Mutations of an intronic repeat induce impaired MRE11 expression in primary human cancer with microsatellite instability. | ||||||||||
| Author: | Giannini, Giuseppe|Rinaldi, Christian|Ristori, Elisabetta|Ambrosini, Maria Irene|Cerignoli, Fabio|Viel, Alessandra|Bidoli, Ettore|Berni, Silvia|D'Amati, Giulia|Scambia, Giovanni|Frati, Luigi|Screpanti, Isabella|Gulino, Alberto | ||||||||||
| PMID: | 15048091 | ||||||||||
| 5. | |||||||||||
| Journal: | Lab Invest. 2005 Sep;85(9):1130-8. | ||||||||||
| Title: | Impaired nonhomologous end-joining in mismatch repair-deficient colon carcinomas. | ||||||||||
| Author: | Koh, Kwi H|Kang, Hyun J|Li, Long S|Kim, Nam-Gyun|You, Kwon T|Yang, Eungi|Kim, Hyunki|Kim, Hee J|Yun, Chae-Ok|Kim, Kyung-Sup|Kim, Hoguen | ||||||||||
| PMID: | 16025146 | ||||||||||
| 6. | |||||||||||
| Journal: | Dis Colon Rectum. 2006 Mar;49(3):399-406. | ||||||||||
| Title: | Accumulation profile of frameshift mutations during development and progression of colorectal cancer from patients with hereditary nonpolyposis colorectal cancer. | ||||||||||
| Author: | Yamaguchi, Tatsuro|Iijima, Takeru|Mori, Takeo|Takahashi, Keiichi|Matsumoto, Hiroshi|Miyamoto, Hidenori|Hishima, Tsunekazu|Miyaki, Michiko | ||||||||||
| PMID: | 16421660 | ||||||||||
| 7. | |||||||||||
| Journal: | J Biol Chem. 2006 Oct 13;281(41):30814-23. Epub 2006 Aug 10. | ||||||||||
| Title: | Defective Mre11-dependent activation of Chk2 by ataxia telangiectasia mutated in colorectal carcinoma cells in response to replication-dependent DNA double strand breaks. | ||||||||||
| Author: | Takemura, Haruyuki|Rao, V Ashutosh|Sordet, Olivier|Furuta, Takahisa|Miao, Ze-Hong|Meng, Linghua|Zhang, Hongliang|Pommier, Yves | ||||||||||
| PMID: | 16905549 | ||||||||||
| 8. | |||||||||||
| Journal: | Eur J Hum Genet. 2007 Sep;15(9):922-9. Epub 2007 May 30. | ||||||||||
| Title: | The MRE11/RAD50/NBS1 complex destabilization in Lynch-syndrome patients. | ||||||||||
| Author: | Alemayehu, Aster|Fridrichova, Ivana | ||||||||||
| PMID: | 17534377 | ||||||||||
| 9. | |||||||||||
| Journal: | Histol Histopathol. 2008 Dec;23(12):1495-502. | ||||||||||
| Title: | RAD50/MRE11/NBS1 proteins in relation to tumour development and prognosis in patients with microsatellite stable colorectal cancer. | ||||||||||
| Author: | Gao, Jingfang|Zhang, Hong|Arbman, Gunnar|Sun, Xiao-Feng | ||||||||||
| PMID: | 18830935 | ||||||||||
| 10. | |||||||||||
| Journal: | Br J Cancer. 2008 Nov 18;99(10):1607-12. | ||||||||||
| Title: | Microsatellite instability due to hMLH1 deficiency is associated with increased cytotoxicity to irinotecan in human colorectal cancer cell lines. | ||||||||||
| Author: | Vilar, E|Scaltriti, M|Balmana, J|Saura, C|Guzman, M|Arribas, J|Baselga, J|Tabernero, J | ||||||||||
| PMID: | 18941461 | ||||||||||
| 11. | |||||||||||
| Journal: | Mutat Res. 2008 Sep-Oct;659(3):262-73. | ||||||||||
| Title: | The importance of making ends meet: mutations in genes and altered expression of proteins of the MRN complex and cancer. | ||||||||||
| Author: | Dzikiewicz-Krawczyk, Agnieszka | ||||||||||
| PMID: | 18606567 | ||||||||||
| 12. | |||||||||||
| Journal: | Mol Biol Cell. 2008 Apr;19(4):1693-705. | ||||||||||
| Title: | A mutant allele of MRE11 found in mismatch repair-deficient tumor cells suppresses the cellular response to DNA replication fork stress in a dominant negative manner. | ||||||||||
| Author: | Wen, Qin|Scorah, Jennifer|Phear, Geraldine|Rodgers, Gary|Rodgers, Sheila|Meuth, Mark | ||||||||||
| PMID: | 18256278 | ||||||||||
| 13. | |||||||||||
| Journal: | Dis Markers. 2008;24(2):127-34. | ||||||||||
| Title: | The different roles of hRAD50 in microsatellite stable and unstable colorectal cancers. | ||||||||||
| Author: | Gao, Jingfang|Zhang, Hong|Arbman, Gunnar|Sun, Xiao-Feng | ||||||||||
| PMID: | 18219098 | ||||||||||
| 14. | |||||||||||
| Journal: | Mol Cancer Res. 2010 Jul;8(7):952-60. | ||||||||||
| Title: | Mutations in the circadian gene CLOCK in colorectal cancer. | ||||||||||
| Author: | Alhopuro, Pia|Bjorklund, Mikael|Sammalkorpi, Heli|Turunen, Mikko|Tuupanen, Sari|Bistrom, Mia|Niittymaki, Iina|Lehtonen, Heli J|Kivioja, Teemu|Launonen, Virpi|Saharinen, Juha|Nousiainen, Kari|Hautaniemi, Sampsa|Nuorva, Kyosti|Mecklin, Jukka-Pekka|Jarvinen, | ||||||||||
| PMID: | 20551151 | ||||||||||
| 15. | |||||||||||
| Journal: | J Transl Med. 2012 May 29;10:109. | ||||||||||
| Title: | Expression of AEG-1 mRNA and protein in colorectal cancer patients and colon cancer cell lines. | ||||||||||
| Author: | Gnosa, Sebastian|Shen, Yang-Mei|Wang, Chao-Jie|Zhang, Hong|Stratmann, Johannes|Arbman, Gunnar|Sun, Xiao-Feng | ||||||||||
| PMID: | 22643064 | ||||||||||
| 16. | |||||||||||
| Journal: | Tumour Biol. 2013 Aug;34(4):2141-6. | ||||||||||
| Title: | Clinicopathological significance of BTF3 expression in colorectal cancer. | ||||||||||
| Author: | Wang, Chao-Jie|Franbergh-Karlson, Hanna|Wang, Da-Wei|Arbman, Gunnar|Zhang, Hong|Sun, Xiao-Feng | ||||||||||
| PMID: | 23532689 | ||||||||||
| 17. | |||||||||||
| Journal: | Mol Cancer Ther. 2014 May;13(5):1170-80. | ||||||||||
| Title: | The use of Olaparib (AZD2281) potentiates SN-38 cytotoxicity in colon cancer cells by indirect inhibition of Rad51-mediated repair of DNA double-strand breaks. | ||||||||||
| Author: | Tahara, Makiko|Inoue, Takeshi|Sato, Futoshi|Miyakura, Yasuyuki|Horie, Hisanaga|Yasuda, Yoshikazu|Fujii, Hirofumi|Kotake, Kenjiro|Sugano, Kokichi | ||||||||||
| PMID: | 24577941 | ||||||||||
| 18. | |||||||||||
| Journal: | Medicine (Baltimore). 2015 Dec;94(51):e2350. | ||||||||||
| Title: | Prognostic Significance and Molecular Features of Colorectal Mucinous Adenocarcinomas: A Strobe-Compliant Study. | ||||||||||
| Author: | Wang, Mo-Jin|Ping, Jie|Li, Yuan|Holmqvist, Annica|Adell, Gunnar|Arbman, Gunnar|Zhang, Hong|Zhou, Zong-Guang|Sun, Xiao-Feng | ||||||||||
| PMID: | 26705231 | ||||||||||
| 19. | |||||||||||
| Journal: | Cancers (Basel). 2017 Nov 30;9(12). pii: cancers9120163. | ||||||||||
| Title: | Early Postoperative Low Expression of RAD50 in Rectal Cancer Patients Associates with Disease-Free Survival. | ||||||||||
| Author: | Ho, Vincent|Chung, Liping|Singh, Amandeep|Lea, Vivienne|Revoltar, Maxine|Lim, Stephanie H|Tut, Thein-Ga|Ng, Weng|Lee, Mark|de Souza, Paul|Shin, Joo-Shik|Soon Lee, Cheok | ||||||||||
| PMID: | 29189711 | ||||||||||
| 20. | |||||||||||
| Journal: | Oncogene. 2018 Jan 25;37(4):427-438. | ||||||||||
| Title: | AKT overactivation can suppress DNA repair via p70S6 kinase-dependent downregulation of MRE11. | ||||||||||
| Author: | Piscitello, D|Varshney, D|Lilla, S|Vizioli, M G|Reid, C|Gorbunova, V|Seluanov, A|Gillespie, D A|Adams, P D | ||||||||||
| PMID: | 28967905 | ||||||||||
| 21. | |||||||||||
| Journal: | Neoplasma. 2018;65(1):75-80. | ||||||||||
| Title: | Targeting RAD50 increases sensitivity to radiotherapy in colorectal cancer cells. | ||||||||||
| Author: | Chen, C|Wang, Y|Mei, J F|Li, S S|Xu, H X|Xiong, H P|Wang, X H|He, X | ||||||||||
| PMID: | 29322791 | ||||||||||
| 22. | |||||||||||
| Journal: | BMC Cancer. 2018 Sep 3;18(1):869. | ||||||||||
| Title: | Overexpression of the MRE11-RAD50-NBS1 (MRN) complex in rectal cancer correlates with poor response to neoadjuvant radiotherapy and prognosis. | ||||||||||
| Author: | Ho, Vincent|Chung, Liping|Singh, Amandeep|Lea, Vivienne|Abubakar, Askar|Lim, Stephanie H|Ng, Weng|Lee, Mark|de Souza, Paul|Shin, Joo-Shik|Lee, Cheok Soon | ||||||||||
| PMID: | 30176843 | ||||||||||