Literatures

Primary Site >> Colorectal Cancer

Gene >> RAC1

1.
Journal:	Cancer Res. 1990 Jul 15;50(14):4401-6.
Title:	Formulation, stability, and antitumor activity of 1-beta-D-arabinofuranosylcytosine conjugate of thioether phospholipid.
Author:	Hong, C I\|Bernacki, R J\|Hui, S W\|Rustum, Y\|West, C R
PMID:	2364392

2.
Journal:	Lipids. 1991 Dec;26(12):1437-44.
Title:	1-beta-D-arabinofuranosylcytosine conjugates of ether and thioether phospholipids. A new class of ara-C prodrug with improved antitumor activity.
Author:	Hong, C I\|West, C R\|Bernacki, R J\|Tebbi, C K\|Berdel, W E
PMID:	1819747

3.
Journal:	Exp Cell Res. 1999 Dec 15;253(2):533-40.
Title:	Activated Rac1 selectively up-regulates the expression of integrin alpha6beta4 and induces cell adhesion and membrane ruffles of nonadherent colon cancer Colo201 cells.
Author:	Mohri, T\|Adachi, Y\|Ikehara, S\|Hioki, K\|Tokunaga, R\|Taketani, S
PMID:	10585277

4.
Journal:	FASEB J. 2000 Nov;14(14):2329-38.
Title:	Leptin promotes invasiveness of kidney and colonic epithelial cells via phosphoinositide 3-kinase-, rho-, and rac-dependent signaling pathways.
Author:	Attoub, S\|Noe, V\|Pirola, L\|Bruyneel, E\|Chastre, E\|Mareel, M\|Wymann, M P\|Gespach, C
PMID:	11053255

5.
Journal:	Cancer Lett. 2002 Feb 8;176(1):101-9.
Title:	Immunohistochemical analysis of IQGAP1 expression in human colorectal carcinomas: its overexpression in carcinomas and association with invasion fronts.
Author:	Nabeshima, Kazuki\|Shimao, Yoshiya\|Inoue, Teruhiko\|Koono, Masashi
PMID:	11790459

6.
Journal:	Mol Cell Neurosci. 2002 Jan;19(1):1-17.
Title:	The netrin-1 receptor DCC promotes filopodia formation and cell spreading by activating Cdc42 and Rac1.
Author:	Shekarabi, Masoud\|Kennedy, Timothy E
PMID:	11817894

7.
Journal:	J Biol Chem. 2002 Apr 26;277(17):15207-14. Epub 2002 Feb 13.
Title:	Rac1 and Cdc42 but not RhoA or Rho kinase activities are required for neurite outgrowth induced by the Netrin-1 receptor DCC (deleted in colorectal cancer) in N1E-115 neuroblastoma cells.
Author:	Li, Xiaodong\|Saint-Cyr-Proulx, Etienne\|Aktories, Klaus\|Lamarche-Vane, Nathalie
PMID:	11844789

8.
Journal:	J Biol Chem. 2002 Oct 4;277(40):37788-97. Epub 2002 Jul 30.
Title:	The adaptor protein Nck-1 couples the netrin-1 receptor DCC (deleted in colorectal cancer) to the activation of the small GTPase Rac1 through an atypical mechanism.
Author:	Li, Xiaodong\|Meriane, Mayya\|Triki, Ibtissem\|Shekarabi, Masoud\|Kennedy, Timothy E\|Larose, Louise\|Lamarche-Vane, Nathalie
PMID:	12149262

9.
Journal:	Virchows Arch. 2002 Aug;441(2):124-32. Epub 2002 Feb 19.
Title:	Complex formation of IQGAP1 with E-cadherin/catenin during cohort migration of carcinoma cells. Its possible association with localized release from cell-cell adhesion.
Author:	Shimao, Yoshiya\|Nabeshima, Kazuki\|Inoue, Teruhiko\|Koono, Masashi
PMID:	12189501

10.
Journal:	Oncogene. 2002 Oct 3;21(44):6740-50.
Title:	Bile acids stimulate invasion and haptotaxis in human colorectal cancer cells through activation of multiple oncogenic signaling pathways.
Author:	Debruyne, P R\|Bruyneel, E A\|Karaguni, I-M\|Li, Xd\|Flatau, G\|Muller, O\|Zimber, A\|Gespach, C\|Mareel, M M
PMID:	12360401

11.
Journal:	Int J Cancer. 2003 May 10;104(6):722-7.
Title:	Differential effects between amphoterin and advanced glycation end products on colon cancer cells.
Author:	Kuniyasu, Hiroki\|Chihara, Yoshitomo\|Kondo, Hideaki
PMID:	12640679

12.
Journal:	Cancer Cell. 2003 Jul;4(1):67-79.
Title:	ERK-MAPK signaling coordinately regulates activity of Rac1 and RhoA for tumor cell motility.
Author:	Vial, Emmanuel\|Sahai, Erik\|Marshall, Christopher J
PMID:	12892714

13.
Journal:	J Biol Chem. 2003 Dec 12;278(50):50442-8.
Title:	Tumor-related alternatively spliced Rac1b is not regulated by Rho-GDP dissociation inhibitors and exhibits selective downstream signaling.
Author:	Matos, Paulo\|Collard, John G\|Jordan, Peter
PMID:	14506233

14.
Journal:	Carcinogenesis. 2004 Jul;25(7):1293-8. Epub 2004 Feb 19.
Title:	DNA array analysis of the effects of aspirin on colon cancer cells: involvement of Rac1.
Author:	Hardwick, James C H\|van Santen, Marije\|van den Brink, Gijs R\|van Deventer, Sander J H\|Peppelenbosch, Maikel P
PMID:	14976132

15.
Journal:	J Immunol. 2004 Mar 1;172(5):3051-8.
Title:	Role of nicotinamide adenine dinucleotide phosphate oxidase 1 in oxidative burst response to Toll-like receptor 5 signaling in large intestinal epithelial cells.
Author:	Kawahara, Tsukasa\|Kuwano, Yuki\|Teshima-Kondo, Shigetada\|Takeya, Ryu\|Sumimoto, Hideki\|Kishi, Kyoichi\|Tsunawaki, Shohko\|Hirayama, Toshiya\|Rokutan, Kazuhito
PMID:	14978110

16.
Journal:	J Biol Chem. 2004 May 21;279(21):22118-23.
Title:	Protein kinase C (PKC) betaII induces cell invasion through a Ras/Mek-, PKC iota/Rac 1-dependent signaling pathway.
Author:	Zhang, Jie\|Anastasiadis, Panos Z\|Liu, Yan\|Thompson, E Aubrey\|Fields, Alan P
PMID:	15037605

17.
Journal:	Mol Carcinog. 2004 Apr;39(4):206-20.
Title:	LyGDI functions in cancer metastasis by anchoring Rho proteins to the cell membrane.
Author:	Ota, Takahide\|Maeda, Masayo\|Suto, Shiho\|Tatsuka, Masaaki
PMID:	15057873

18.
Journal:	Oncogene. 2004 Oct 28;23(50):8260-71.
Title:	Cross-talk between Rac1 GTPase and dysregulated Wnt signaling pathway leads to cellular redistribution of beta-catenin and TCF/LEF-mediated transcriptional activation.
Author:	Esufali, S\|Bapat, B
PMID:	15377999

19.
Journal:	Oncogene. 2004 Dec 16;23(58):9369-80.
Title:	Rac1b, a tumor associated, constitutively active Rac1 splice variant, promotes cellular transformation.
Author:	Singh, Anurag\|Karnoub, Antoine E\|Palmby, Todd R\|Lengyel, Ernst\|Sondek, John\|Der, Channing J
PMID:	15516977

20.
Journal:	Am J Pathol. 2005 Mar;166(3):751-60.
Title:	Colon cancer cell-derived high mobility group 1/amphoterin induces growth inhibition and apoptosis in macrophages.
Author:	Kuniyasu, Hiroki\|Yano, Seiji\|Sasaki, Takamitsu\|Sasahira, Tomonori\|Sone, Sabro\|Ohmori, Hitoshi
PMID:	15743787

21.
Journal:	J Neurosci. 2005 Mar 23;25(12):3132-41.
Title:	Deleted in colorectal cancer binding netrin-1 mediates cell substrate adhesion and recruits Cdc42, Rac1, Pak1, and N-WASP into an intracellular signaling complex that promotes growth cone expansion.
Author:	Shekarabi, Masoud\|Moore, Simon W\|Tritsch, Nicolas X\|Morris, Stephen J\|Bouchard, Jean-Francois\|Kennedy, Timothy E
PMID:	15788770

22.
Journal:	Oncogene. 2005 Dec 15;24(56):8240-51.
Title:	Commutators of PAR-1 signaling in cancer cell invasion reveal an essential role of the Rho-Rho kinase axis and tumor microenvironment.
Author:	Nguyen, Quang-De\|De Wever, Olivier\|Bruyneel, Erik\|Hendrix, An\|Xie, Wan-Zhuo\|Lombet, Alain\|Leibl, Martin\|Mareel, Marc\|Gieseler, Frank\|Bracke, Marc\|Gespach, Christian
PMID:	16091733

23.
Journal:	J Biol Chem. 2006 May 12;281(19):13724-32. Epub 2006 Mar 21.
Title:	Rac1, but not Rac1B, stimulates RelB-mediated gene transcription in colorectal cancer cells.
Author:	Matos, Paulo\|Jordan, Peter
PMID:	16551621

24.
Journal:	Biochim Biophys Acta. 2007 Feb;1773(2):120-30.
Title:	Characterization of a 60S complex of the adenomatous polyposis coli tumor suppressor protein.
Author:	Mahadevaiyer, Sreekala\|Xu, Chong\|Gumbiner, Barry M
PMID:	17126424

25.
Journal:	Mol Cell Biol. 2007 Feb;27(4):1380-93. Epub 2006 Dec 4.
Title:	Asef2 functions as a Cdc42 exchange factor and is stimulated by the release of an autoinhibitory module from a concealed C-terminal activation element.
Author:	Hamann, Michael J\|Lubking, Casey M\|Luchini, Doris N\|Billadeau, Daniel D
PMID:	17145773

26.
Journal:	Cancer Res. 2007 Mar 15;67(6):2469-79.
Title:	Activation of tumor-specific splice variant Rac1b by dishevelled promotes canonical Wnt signaling and decreased adhesion of colorectal cancer cells.
Author:	Esufali, Susmita\|Charames, George S\|Pethe, Vaijayanti V\|Buongiorno, Pinella\|Bapat, Bharati
PMID:	17363564

27.
Journal:	Cancer Res. 2007 Apr 1;67(7):2922-6.
Title:	PRL-3 down-regulates PTEN expression and signals through PI3K to promote epithelial-mesenchymal transition.
Author:	Wang, Haihe\|Quah, Samantha Yiling\|Dong, Jing Ming\|Manser, Edward\|Tang, Jing Ping\|Zeng, Qi
PMID:	17409395

28.
Journal:	Cell Signal. 2007 Aug;19(8):1722-32. Epub 2007 Mar 28.
Title:	Proinvasive activity of BMP-7 through SMAD4/src-independent and ERK/Rac/JNK-dependent signaling pathways in colon cancer cells.
Author:	Grijelmo, Clara\|Rodrigue, Christelle\|Svrcek, Magalie\|Bruyneel, Erik\|Hendrix, An\|de Wever, Olivier\|Gespach, Christian
PMID:	17478078

29.
Journal:	Oncogene. 2007 Dec 6;26(55):7620-267. Epub 2007 Jun 18.
Title:	Identification and characterization of Asef2, a guanine-nucleotide exchange factor specific for Rac1 and Cdc42.
Author:	Kawasaki, Y\|Sagara, M\|Shibata, Y\|Shirouzu, M\|Yokoyama, S\|Akiyama, T
PMID:	17599059

30.
Journal:	J Cell Sci. 2007 Aug 1;120(Pt 15):2672-82. Epub 2007 Jul 17.
Title:	Mechanical force modulates global gene expression and beta-catenin signaling in colon cancer cells.
Author:	Avvisato, Christopher L\|Yang, Xiang\|Shah, Salim\|Hoxter, Becky\|Li, Weiqun\|Gaynor, Richard\|Pestell, Richard\|Tozeren, Aydin\|Byers, Stephen W
PMID:	17635998

31.
Journal:	Int J Biochem Cell Biol. 2007;39(12):2289-302. Epub 2007 Jul 4.
Title:	Differential expression of Rac1 identifies its target genes and its contribution to progression of colorectal cancer.
Author:	Gomez del Pulgar, Teresa\|Bandres, Eva\|Espina, Carolina\|Valdes-Mora, Fatima\|Perez-Palacios, Rosa\|Garcia-Amigot, Fermin\|Garcia-Foncillas, Jesus\|Lacal, Juan Carlos
PMID:	17766170

32.
Journal:	Zhonghua Zhong Liu Za Zhi. 2007 Sep;29(9):666-9.
Title:	[Role of Rac1 activation in migration and invasion of colorectal cancer cell line SW480].
Author:	Nan, Qing-Zhen\|Gao, Lei\|Zhang, Zhen-Shu
PMID:	18246795

33.
Journal:	Dig Dis Sci. 2008 Feb;53(2):467-73. Epub 2007 Jun 28.
Title:	The activity of RhoA is correlated with lymph node metastasis in human colorectal cancer.
Author:	Takami, Yoji\|Higashi, Morihiro\|Kumagai, Shinpei\|Kuo, Paul C\|Kawana, Hidetada\|Koda, Keiji\|Miyazaki, Masaru\|Harigaya, Kenichi
PMID:	17597401

34.
Journal:	Int J Cancer. 2008 Apr 15;122(8):1757-64.
Title:	Nox1 downstream of 12-lipoxygenase controls cell proliferation but not cell spreading of colon cancer cells.
Author:	de Carvalho, Daniela D\|Sadok, Amine\|Bourgarel-Rey, Veronique\|Gattacceca, Florence\|Penel, Claude\|Lehmann, Maxime\|Kovacic, Herve
PMID:	18076063

35.
Journal:	Am J Pathol. 2008 Jan;172(1):156-66.
Title:	A critical role for Rac1 in tumor progression of human colorectal adenocarcinoma cells.
Author:	Espina, Carolina\|Cespedes, Maria Virtudes\|Garcia-Cabezas, Miguel Angel\|Gomez del Pulgar, Maria Teresa\|Boluda, Alicia\|Oroz, Lourdes Garcia\|Benitah, Salvador A\|Cejas, Paloma\|Nistal, Manuel\|Mangues, Ramon\|Lacal, Juan Carlos
PMID:	18165265

36.
Journal:	Mol Cell Biol. 2008 Apr;28(7):2314-23.
Title:	Trio mediates netrin-1-induced Rac1 activation in axon outgrowth and guidance.
Author:	Briancon-Marjollet, Anne\|Ghogha, Atefeh\|Nawabi, Homaira\|Triki, Ibtissem\|Auziol, Camille\|Fromont, Sylvie\|Piche, Chantal\|Enslen, Herve\|Chebli, Karim\|Cloutier, Jean-Francois\|Castellani, Valerie\|Debant, Anne\|Lamarche-Vane, Nathalie
PMID:	18212043

37.
Journal:	Cell Mol Life Sci. 2008 May;65(9):1446-57.
Title:	Pressure activates colon cancer cell adhesion via paxillin phosphorylation, Crk, Cas, and Rac1.
Author:	Downey, C\|Craig, D H\|Basson, M D
PMID:	18392556

38.
Journal:	Cancer Lett. 2008 Aug 8;266(2):263-74.
Title:	Differential impact of TGF-beta and EGF on fibroblast differentiation and invasion reciprocally promotes colon cancer cell invasion.
Author:	Denys, Hannelore\|Derycke, Lara\|Hendrix, An\|Westbroek, Wendy\|Gheldof, Alexander\|Narine, Kishan\|Pauwels, Patrick\|Gespach, Christian\|Bracke, Marc\|De Wever, Olivier
PMID:	18423981

39.
Journal:	Mol Biol Cell. 2008 Jul;19(7):2984-94.
Title:	The involvement of the tyrosine kinase c-Src in the regulation of reactive oxygen species generation mediated by NADPH oxidase-1.
Author:	Gianni, Davide\|Bohl, Ben\|Courtneidge, Sara A\|Bokoch, Gary M
PMID:	18463161

40.
Journal:	Biochem J. 2008 Oct 1;415(1):57-65.
Title:	Activation of NADPH oxidase 1 in tumour colon epithelial cells.
Author:	Nisimoto, Yukio\|Tsubouchi, Ryoko\|Diebold, Becky A\|Qiao, Shanlou\|Ogawa, Hisamitsu\|Ohara, Takuya\|Tamura, Minoru
PMID:	18518859

41.
Journal:	Gastroenterology. 2008 Sep;135(3):899-906.
Title:	B-Raf(V600E) cooperates with alternative spliced Rac1b to sustain colorectal cancer cell survival.
Author:	Matos, Paulo\|Oliveira, Carla\|Velho, Sergia\|Goncalves, Vania\|da Costa, Luis Teixiera\|Moyer, Mary Pat\|Seruca, Raquel\|Jordan, Peter
PMID:	18602919

42.
Journal:	Mol Cancer Res. 2008 Jul;6(7):1178-84.
Title:	Increased Rac1b expression sustains colorectal tumor cell survival.
Author:	Matos, Paulo\|Jordan, Peter
PMID:	18644982

43.
Journal:	J Cell Sci. 2008 Sep 1;121(Pt 17):2805-13.
Title:	Rac regulates the interaction of fascin with protein kinase C in cell migration.
Author:	Parsons, Maddy\|Adams, Josephine C
PMID:	18716283

44.
Journal:	Int J Cancer. 2008 Dec 1;123(11):2543-56.
Title:	Leptin promotes motility and invasiveness in human colon cancer cells by activating multiple signal-transduction pathways.
Author:	Jaffe, Tamara\|Schwartz, Betty
PMID:	18767036

45.
Journal:	Mol Cancer. 2008 Sep 30;7:73.
Title:	Rac1 GTPase and the Rac1 exchange factor Tiam1 associate with Wnt-responsive promoters to enhance beta-catenin/TCF-dependent transcription in colorectal cancer cells.
Author:	Buongiorno, Pinella\|Pethe, Vaijayanti V\|Charames, George S\|Esufali, Susmita\|Bapat, Bharati
PMID:	18826597

46.
Journal:	Free Radic Biol Med. 2008 Dec 15;45(12):1642-52.
Title:	Tumor necrosis factor alpha activates transcription of the NADPH oxidase organizer 1 (NOXO1) gene and upregulates superoxide production in colon epithelial cells.
Author:	Kuwano, Yuki\|Tominaga, Kumiko\|Kawahara, Tsukasa\|Sasaki, Hidekazu\|Takeo, Keiko\|Nishida, Kensei\|Masuda, Kiyoshi\|Kawai, Tomoko\|Teshima-Kondo, Shigetada\|Rokutan, Kazuhito
PMID:	18929641

47.
Journal:	Mol Cell Biochem. 2009 Feb;322(1-2):179-84.
Title:	Inhibition of migration and invasion of colorectal cancer cells via deletion of Rac1 with RNA interference.
Author:	Zhao, Shi-Yi\|Sun, Yan\|Lai, Zhuo-Sheng\|Nan, Qing-Zhen\|Li, Kang\|Zhang, Zhen-Shu
PMID:	19009236

48.
Journal:	Oncogene. 2009 Mar 12;28(10):1357-65.
Title:	Asef2 and Neurabin2 cooperatively regulate actin cytoskeletal organization and are involved in HGF-induced cell migration.
Author:	Sagara, M\|Kawasaki, Y\|Iemura, S-i\|Natsume, T\|Takai, Y\|Akiyama, T
PMID:	19151759

49.
Journal:	Cancer Biol Ther. 2009 Apr;8(8):689-95. Epub 2009 Apr 9.
Title:	Expression of Tiam1 and VEGF-C correlates with lymphangiogenesis in human colorectal carcinoma.
Author:	Zhong, Daping\|Li, Yan\|Peng, Qiuping\|Zhou, Jinming\|Zhou, Qi\|Zhang, Rong\|Liang, Houjie
PMID:	19276682

50.
Journal:	Lab Invest. 2009 May;89(5):531-48.
Title:	NGAL decreases E-cadherin-mediated cell-cell adhesion and increases cell motility and invasion through Rac1 in colon carcinoma cells.
Author:	Hu, Limei\|Hittelman, Walter\|Lu, Tao\|Ji, Ping\|Arlinghaus, Ralph\|Shmulevich, Ilya\|Hamilton, Stanley R\|Zhang, Wei
PMID:	19308044

51.
Journal:	Int J Cancer. 2009 Aug 1;125(3):548-55.
Title:	P21-activated kinase 5 is overexpressed during colorectal cancer progression and regulates colorectal carcinoma cell adhesion and migration.
Author:	Gong, Wei\|An, Zhengwen\|Wang, Yunling\|Pan, Xinyan\|Fang, Weigang\|Jiang, Bo\|Zhang, Hongquan
PMID:	19415746

52.
Journal:	Carcinogenesis. 2009 Sep;30(9):1475-86.
Title:	Over-expression of EphB3 enhances cell-cell contacts and suppresses tumor growth in HT-29 human colon cancer cells.
Author:	Chiu, Sou-Tyau\|Chang, King-Jen\|Ting, Chen-Hung\|Shen, Hsi-Che\|Li, Hung\|Hsieh, Fon-Jou
PMID:	19483190

53.
Journal:	J Biol Chem. 2009 Aug 14;284(33):22436-43.
Title:	Adenomatous polyposis coli and Asef function downstream of hepatocyte growth factor and phosphatidylinositol 3-kinase.
Author:	Kawasaki, Yoshihiro\|Tsuji, Shinnosuke\|Sagara, Masaki\|Echizen, Kanae\|Shibata, Yoko\|Akiyama, Tetsu
PMID:	19525225

54.
Journal:	Exp Mol Med. 2009 Oct 31;41(10):717-27.
Title:	Triptolide downregulates Rac1 and the JAK/STAT3 pathway and inhibits colitis-related colon cancer progression.
Author:	Wang, Zhipeng\|Jin, Haifeng\|Xu, Ruodan\|Mei, Qibing\|Fan, Daiming
PMID:	19561401

55.
Journal:	Hum Mol Genet. 2009 Oct 1;18(19):3696-707.
Title:	Antagonistic SR proteins regulate alternative splicing of tumor-related Rac1b downstream of the PI3-kinase and Wnt pathways.
Author:	Goncalves, Vania\|Matos, Paulo\|Jordan, Peter
PMID:	19602482

56.
Journal:	Sichuan Da Xue Xue Bao Yi Xue Ban. 2009 Jul;40(4):588-92.
Title:	[The effect of Rac1 siRNA on the biological behaviors of gastrointestinal cancer cells].
Author:	Huang, Juan\|Lan, Nan\|Liu, Ming\|Chen, Ji\|Zhou, Ji-Tao\|Zhu, Ya-Jie\|Liu, Su-Rui\|Tang, Qiu-Lin\|Chen, Xiang-Zheng\|Bi, Feng
PMID:	19764550

57.
Journal:	Mol Carcinog. 2010 Mar;49(3):235-46.
Title:	The synergistic anticancer effect of troglitazone combined with aspirin causes cell cycle arrest and apoptosis in human lung cancer cells.
Author:	Yan, Kun-Huang\|Yao, Chih-Jung\|Chang, Hwan-You\|Lai, Gi-Ming\|Cheng, Ann-Lii\|Chuang, Shuang-En
PMID:	19908241

58.
Journal:	Int J Cancer. 2010 Sep 1;127(5):1220-9.
Title:	Isoalvaxanthone inhibits colon cancer cell proliferation, migration and invasion through inactivating Rac1 and AP-1.
Author:	Wang, Lei\|Kuang, Lisha\|Pan, Xinhua\|Liu, Junchen\|Wang, Qian\|Du, Bing\|Li, Dali\|Luo, Jian\|Liu, Mingyao\|Hou, Aijun\|Qian, Min
PMID:	20017136

59.
Journal:	PLoS One. 2010 Jan 27;5(1):e8925.
Title:	Interaction of Saccharomyces boulardii with Salmonella enterica serovar Typhimurium protects mice and modifies T84 cell response to the infection.
Author:	Martins, Flaviano S\|Dalmasso, Guillaume\|Arantes, Rosa M E\|Doye, Anne\|Lemichez, Emmanuel\|Lagadec, Patricia\|Imbert, Veronique\|Peyron, Jean-Francois\|Rampal, Patrick\|Nicoli, Jacques R\|Czerucka, Dorota
PMID:	20111723

60.
Journal:	Carcinogenesis. 2010 Apr;31(4):597-606.
Title:	TMPRSS4 induces invasion and epithelial-mesenchymal transition through upregulation of integrin alpha5 and its signaling pathways.
Author:	Kim, Semi\|Kang, Hee Young\|Nam, Eun-Hee\|Choi, Myung-Sook\|Zhao, Xue-Feng\|Hong, Chang Soo\|Lee, Jung Weon\|Lee, Jae Hyuk\|Park, Young-Kyu
PMID:	20118200

61.
Journal:	Am J Physiol Cell Physiol. 2010 Aug;299(2):C454-63.
Title:	PTP-PEST controls motility, adherens junction assembly, and Rho GTPase activity in colon cancer cells.
Author:	Espejo, Rosario\|Rengifo-Cam, William\|Schaller, Michael D\|Evers, B Mark\|Sastry, Sarita K
PMID:	20519451

62.
Journal:	J Biol Chem. 2010 Aug 6;285(32):24987-98.
Title:	Tuberous sclerosis complex 2 (TSC2) regulates cell migration and polarity through activation of CDC42 and RAC1.
Author:	Larson, Yan\|Liu, Jianyu\|Stevens, Payton D\|Li, Xin\|Li, Jing\|Evers, B Mark\|Gao, Tianyan
PMID:	20530489

63.
Journal:	Tumour Biol. 2010 Dec;31(6):575-82.
Title:	p21-activated kinase 5 inhibits camptothecin-induced apoptosis in colorectal carcinoma cells.
Author:	Wang, Xia\|Gong, Wei\|Qing, Haitao\|Geng, Yan\|Wang, Xinying\|Zhang, Yongsheng\|Peng, Liang\|Zhang, Hongquan\|Jiang, Bo
PMID:	20567954

64.
Journal:	Nan Fang Yi Ke Da Xue Xue Bao. 2010 Jun;30(6):1339-42.
Title:	[Effect of small interfering RNA targeting Rac1 gene on colony formation of SW480 cells in vitro].
Author:	Nan, Qing-zhen\|Gao, Lei\|Xiao, Bing\|Zhang, Zhen-shu\|Jiang, Bo
PMID:	20584673

65.
Journal:	Cancer Lett. 2010 Dec 1;298(1):119-27.
Title:	PTHrP promotes colon cancer cell migration and invasion in an integrin alpha6beta4-dependent manner through activation of Rac1.
Author:	Mula, Ramanjaneya V\|Bhatia, Vandanajay\|Falzon, Miriam
PMID:	20637541

66.
Journal:	Cancer Res. 2010 Oct 1;70(19):7710-22.
Title:	Implication of metastasis suppressor NM23-H1 in maintaining adherens junctions and limiting the invasive potential of human cancer cells.
Author:	Boissan, Mathieu\|De Wever, Olivier\|Lizarraga, Floria\|Wendum, Dominique\|Poincloux, Renaud\|Chignard, Nicolas\|Desbois-Mouthon, Christele\|Dufour, Sylvie\|Nawrocki-Raby, Beatrice\|Birembaut, Philippe\|Bracke, Marc\|Chavrier, Philippe\|Gespach, Christian\|Lacombe, Ma
PMID:	20841469

67.
Journal:	Biochem Pharmacol. 2011 May 15;81(10):1192-200.
Title:	Cudratricusxanthone G inhibits human colorectal carcinoma cell invasion by MMP-2 down-regulation through suppressing activator protein-1 activity.
Author:	Kuang, Lisha\|Wang, Lei\|Wang, Qian\|Zhao, Qufei\|Du, Bing\|Li, Dali\|Luo, Jian\|Liu, Mingyao\|Hou, Aijun\|Qian, Min
PMID:	21377450

68.
Journal:	Cancer Res. 2011 May 1;71(9):3246-56.
Title:	mTORC1 and mTORC2 regulate EMT, motility, and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways.
Author:	Gulhati, Pat\|Bowen, Kanika A\|Liu, Jianyu\|Stevens, Payton D\|Rychahou, Piotr G\|Chen, Min\|Lee, Eun Y\|Weiss, Heidi L\|O'Connor, Kathleen L\|Gao, Tianyan\|Evers, B Mark
PMID:	21430067

69.
Journal:	Cancer Lett. 2011 Sep 28;308(2):162-71.
Title:	Thymosin beta 4 induces colon cancer cell migration and clinical metastasis via enhancing ILK/IQGAP1/Rac1 signal transduction pathway.
Author:	Tang, Mei-Chuan\|Chan, Li-Chuan\|Yeh, Yi-Chen\|Chen, Cheng-Yu\|Chou, Teh-Ying\|Wang, Wei-Shu\|Su, Yeu
PMID:	21621326

70.
Journal:	Mol Biol Cell. 2011 Oct;22(19):3734-46.
Title:	The activation of ezrin-radixin-moesin proteins is regulated by netrin-1 through Src kinase and RhoA/Rho kinase activities and mediates netrin-1-induced axon outgrowth.
Author:	Antoine-Bertrand, Judith\|Ghogha, Atefeh\|Luangrath, Vilayphone\|Bedford, Fiona K\|Lamarche-Vane, Nathalie
PMID:	21849478

71.
Journal:	Sichuan Da Xue Xue Bao Yi Xue Ban. 2011 Jul;42(4):451-4, 460.
Title:	[The affect of Si-Rac1b on the malignant biological behaviors of colorectal cancer cell].
Author:	Li, Li-Lan\|Zhou, Hai-Jun\|Yue, Cai-Xia\|Li, Nan-Jing\|Wei, Wen\|Tang, Qiu-Lin\|Bi, Feng
PMID:	21866624

72.
Journal:	Mol Cancer. 2011 Sep 23;10:118.
Title:	BRAF and RAS oncogenes regulate Rho GTPase pathways to mediate migration and invasion properties in human colon cancer cells: a comparative study.
Author:	Makrodouli, Eleni\|Oikonomou, Eftychia\|Koc, Michal\|Andera, Ladislav\|Sasazuki, Takehiko\|Shirasawa, Senji\|Pintzas, Alexander
PMID:	21943101

73.
Journal:	Int J Clin Oncol. 2012 Apr;17(2):137-42.
Title:	Clinical significance of Rho GDP dissociation inhibitor 2 in colorectal carcinoma.
Author:	Fujita, Akihiko\|Shida, Atsuo\|Fujioka, Shuichi\|Kurihara, Hideaki\|Okamoto, Tomoyoshi\|Yanaga, Katsuhiko
PMID:	21698524

74.
Journal:	Oncogene. 2012 Feb 23;31(8):1001-12.
Title:	A Rac1/PAK1 cascade controls beta-catenin activation in colon cancer cells.
Author:	Zhu, G\|Wang, Y\|Huang, B\|Liang, J\|Ding, Y\|Xu, A\|Wu, W
PMID:	21822311

75.
Journal:	Int J Oncol. 2012 Apr;40(4):942-50.
Title:	Aberrant methylation of PSD disturbs Rac1-mediated immune responses governing neutrophil chemotaxis and apoptosis in ulcerative colitis-associated carcinogenesis.
Author:	Kato, Takaharu\|Suzuki, Koichi\|Okada, Shinichiro\|Kamiyama, Hidenori\|Maeda, Takafumi\|Saito, Masaaki\|Koizumi, Kei\|Miyaki, Yuichiro\|Konishi, Fumio
PMID:	22179719

76.
Journal:	Tumour Biol. 2012 Aug;33(4):985-94.
Title:	PAK1-dependent MAPK pathway activation is required for colorectal cancer cell proliferation.
Author:	Qing, Haitao\|Gong, Wei\|Che, Yufang\|Wang, Xinying\|Peng, Liang\|Liang, Yan\|Wang, Weifei\|Deng, Qiliang\|Zhang, Hongquan\|Jiang, Bo
PMID:	22252525

77.
Journal:	FASEB J. 2012 May;26(5):2049-59.
Title:	A crucial role for Nox 1 in redox-dependent regulation of Wnt-beta-catenin signaling.
Author:	Kajla, Seheli\|Mondol, Abdus S\|Nagasawa, Atsushi\|Zhang, Yugen\|Kato, Masayoshi\|Matsuno, Kuniharu\|Yabe-Nishimura, Chihiro\|Kamata, Tohru
PMID:	22278940

78.
Journal:	J Cell Biochem. 2012 Jul;113(7):2319-29.
Title:	Involvement of hnRNP A1 in the matrix metalloprotease-3-dependent regulation of Rac1 pre-mRNA splicing.
Author:	Pelisch, Federico\|Khauv, Davitte\|Risso, Guillermo\|Stallings-Mann, Melody\|Blaustein, Matias\|Quadrana, Leandro\|Radisky, Derek C\|Srebrow, Anabella
PMID:	22345078

79.
Journal:	Clin Exp Metastasis. 2012 Jun;29(5):471-92.
Title:	Insidious role of nitric oxide in migration/invasion of colon cancer cells by upregulating MMP-2/9 via activation of cGMP-PKG-ERK signaling pathways.
Author:	Babykutty, Suboj\|Suboj, Priya\|Srinivas, Priya\|Nair, Asha S\|Chandramohan, K\|Gopala, Srinivas
PMID:	22419013

80.
Journal:	J Cell Biochem. 2012 Aug;113(8):2549-59.
Title:	Rho GTPase signaling in the development of colorectal cancer.
Author:	Leve, Fernanda\|Morgado-Diaz, Jose A
PMID:	22467564

81.
Journal:	Sci Signal. 2012 Jun 12;5(228):ra43.
Title:	The lin-4 microRNA targets the LIN-14 transcription factor to inhibit netrin-mediated axon attraction.
Author:	Zou, Yan\|Chiu, Hui\|Domenger, Dorothee\|Chuang, Chiou-Fen\|Chang, Chieh
PMID:	22692424

82.
Journal:	BioData Min. 2012 Aug 28;5(1):11.
Title:	Murine colon proteome and characterization of the protein pathways.
Author:	Magdeldin, Sameh\|Yoshida, Yutaka\|Li, Huiping\|Maeda, Yoshitaka\|Yokoyama, Munesuke\|Enany, Shymaa\|Zhang, Ying\|Xu, Bo\|Fujinaka, Hidehiko\|Yaoita, Eishin\|Sasaki, Sei\|Yamamoto, Tadashi
PMID:	22929016

83.
Journal:	PLoS One. 2012;7(11):e48344.
Title:	Cooperative anti-invasive effect of Cdc42/Rac1 activation and ROCK inhibition in SW620 colorectal cancer cells with elevated blebbing activity.
Author:	de Toledo, Marion\|Anguille, Christelle\|Roger, Laureline\|Roux, Pierre\|Gadea, Gilles
PMID:	23144867

84.
Journal:	Mol Cell Biol. 2013 Feb;33(4):739-51.
Title:	Tyrosine phosphorylation of the Rho guanine nucleotide exchange factor Trio regulates netrin-1/DCC-mediated cortical axon outgrowth.
Author:	DeGeer, Jonathan\|Boudeau, Jerome\|Schmidt, Susanne\|Bedford, Fiona\|Lamarche-Vane, Nathalie\|Debant, Anne
PMID:	23230270

85.
Journal:	Oncol Rep. 2013 Feb;29(2):605-12.
Title:	DADS downregulates the Rac1-ROCK1/PAK1-LIMK1-ADF/cofilin signaling pathway, inhibiting cell migration and invasion.
Author:	Zhou, Yujuan\|Su, Jian\|Shi, Ling\|Liao, Qianjin\|Su, Qi
PMID:	23233092

86.
Journal:	Eur J Endocrinol. 2013 Apr 29;168(6):795-804.
Title:	RAC1b overexpression in papillary thyroid carcinoma: a role to unravel.
Author:	Silva, Ana Luisa\|Carmo, Francisca\|Bugalho, Maria Joao
PMID:	23482591

87.
Journal:	Mol Cell Biochem. 2013 Jul;379(1-2):171-80.
Title:	Small interfering RNA targeting Rac1 sensitizes colon cancer to dihydroartemisinin-induced cell cycle arrest and inhibited cell migration by suppressing NFkappaB activity.
Author:	Han, Peng\|Luan, Ying\|Liu, Yanlong\|Yu, Zhiwei\|Li, Jingwen\|Sun, Zicheng\|Chen, Gang\|Cui, Binbin
PMID:	23559092

88.
Journal:	Dev Biol. 2013 Jun 15;378(2):122-40.
Title:	APC loss-induced intestinal tumorigenesis in Drosophila: Roles of Ras in Wnt signaling activation and tumor progression.
Author:	Wang, Chenhui\|Zhao, Rui\|Huang, Pin\|Yang, Fu\|Quan, Zhenghui\|Xu, Na\|Xi, Rongwen
PMID:	23570874

89.
Journal:	Cell Stem Cell. 2013 Jun 6;12(6):761-73.
Title:	ROS production and NF-kappaB activation triggered by RAC1 facilitate WNT-driven intestinal stem cell proliferation and colorectal cancer initiation.
Author:	Myant, Kevin B\|Cammareri, Patrizia\|McGhee, Ewan J\|Ridgway, Rachel A\|Huels, David J\|Cordero, Julia B\|Schwitalla, Sarah\|Kalna, Gabriela\|Ogg, Erinn-Lee\|Athineos, Dimitris\|Timpson, Paul\|Vidal, Marcos\|Murray, Graeme I\|Greten, Florian R\|Anderson, Kurt I\|Sansom,
PMID:	23665120

90.
Journal:	Cell Stem Cell. 2013 Jun 6;12(6):635-6.
Title:	The other face of ROS: a driver of stem cell expansion in colorectal cancer.
Author:	Pelicci, Pier Giuseppe\|Dalton, Paola\|Giorgio, Marco
PMID:	23746969

91.
Journal:	Asian J Androl. 2013 Nov;15(6):831-4.
Title:	Testosterone induced apoptosis in colon cancer cells is regulated by PI3K/Rac1 signaling.
Author:	Alkahtani, Saad
PMID:	23770942

92.
Journal:	J Biol Chem. 2013 Aug 23;288(34):24636-46.
Title:	Tumor cell migration and invasion are enhanced by depletion of Rap1 GTPase-activating protein (Rap1GAP).
Author:	Tsygankova, Oxana M\|Wang, Hongbin\|Meinkoth, Judy L
PMID:	23864657

93.
Journal:	Cell Cycle. 2013 Sep 15;12(18):2973-7.
Title:	Rac1 drives intestinal stem cell proliferation and regeneration.
Author:	Myant, Kevin B\|Scopelliti, Alessandro\|Haque, Sara\|Vidal, Marcos\|Sansom, Owen J\|Cordero, Julia B
PMID:	23974108

94.
Journal:	Int J Oncol. 2013 Nov;43(5):1447-55.
Title:	Inhibition of angiopoietin 2 attenuates lumen formation of tumour-associated vessels in vivo.
Author:	Suzuki, Rei\|Yamamoto, Hirofumi\|Ngan, Chew Yee\|Ohtsuka, Masahisa\|Kitani, Kotaro\|Uemura, Mamoru\|Nishimura, Junichi\|Takemasa, Ichiro\|Mizushima, Tsunekazu\|Sekimoto, Mitsugu\|Minamoto, Toshinari\|Doki, Yuichiro\|Mori, Masaki
PMID:	23982687

95.
Journal:	J Biol Chem. 2013 Nov 22;288(47):34019-29.
Title:	The Cdc42/Rac nucleotide exchange factor protein beta1Pix (Pak-interacting exchange factor) modulates beta-catenin transcriptional activity in colon cancer cells: evidence for direct interaction of beta1PIX with beta-catenin.
Author:	Chahdi, Ahmed\|Raufman, Jean-Pierre
PMID:	24129564

96.
Journal:	PLoS One. 2013 Nov 11;8(11):e80609.
Title:	The miR-1-NOTCH3-Asef pathway is important for colorectal tumor cell migration.
Author:	Furukawa, Shiori\|Kawasaki, Yoshihiro\|Miyamoto, Masaya\|Hiyoshi, Masaya\|Kitayama, Joji\|Akiyama, Tetsu
PMID:	24244701

97.
Journal:	J Transl Med. 2013 Nov 27;11:295.
Title:	Targeting Cdc42 with the small molecule drug AZA197 suppresses primary colon cancer growth and prolongs survival in a preclinical mouse xenograft model by downregulation of PAK1 activity.
Author:	Zins, Karin\|Gunawardhana, Sandun\|Lucas, Trevor\|Abraham, Dietmar\|Aharinejad, Seyedhossein
PMID:	24279335

98.
Journal:	PLoS One. 2013 Dec 30;8(12):e83629.
Title:	Cell cycle-dependent Rho GTPase activity dynamically regulates cancer cell motility and invasion in vivo.
Author:	Kagawa, Yoshinori\|Matsumoto, Shinji\|Kamioka, Yuji\|Mimori, Koshi\|Naito, Yoko\|Ishii, Taeko\|Okuzaki, Daisuke\|Nishida, Naohiro\|Maeda, Sakae\|Naito, Atsushi\|Kikuta, Junichi\|Nishikawa, Keizo\|Nishimura, Junichi\|Haraguchi, Naotsugu\|Takemasa, Ichiro\|Mizushima, Tsun
PMID:	24386239

99.
Journal:	J Mol Neurosci. 2014 Mar;52(3):323-30.
Title:	Piezoelectric ceramic (PZT) modulates axonal guidance growth of rat cortical neurons via RhoA, Rac1, and Cdc42 pathways.
Author:	Wen, Jianqiang\|Liu, Meili
PMID:	24203571

100.
Journal:	Carcinogenesis. 2014 Apr;35(4):886-95.
Title:	miR-320a suppresses colorectal cancer progression by targeting Rac1.
Author:	Zhao, Hongchao\|Dong, Taotao\|Zhou, Houmin\|Wang, Linlin\|Huang, Ao\|Feng, Bo\|Quan, Yingjun\|Jin, Runsen\|Zhang, Wenpeng\|Sun, Jing\|Zhang, Daohai\|Zheng, Minhua
PMID:	24265291

101.
Journal:	J Cell Sci. 2014 Feb 1;127(Pt 3):497-508.
Title:	PTP-PEST targets a novel tyrosine site in p120 catenin to control epithelial cell motility and Rho GTPase activity.
Author:	Espejo, Rosario\|Jeng, Yowjiun\|Paulucci-Holthauzen, Adriana\|Rengifo-Cam, William\|Honkus, Krysta\|Anastasiadis, Panos Z\|Sastry, Sarita K
PMID:	24284071

102.
Journal:	BMC Cancer. 2014 Mar 19;14:208.
Title:	Increased diacylglycerol kinase zeta expression in human metastatic colon cancer cells augments Rho GTPase activity and contributes to enhanced invasion.
Author:	Cai, Kun\|Mulatz, Kirk\|Ard, Ryan\|Nguyen, Thanh\|Gee, Stephen H
PMID:	24646293

103.
Journal:	Stem Cells Dev. 2014 Aug 15;23(16):1870-82.
Title:	Netrin-1 induces MMP-12-dependent E-cadherin degradation via the distinct activation of PKCalpha and FAK/Fyn in promoting mesenchymal stem cell motility.
Author:	Lee, Sei-Jung\|Jung, Young Hyun\|Oh, Sang Yub\|Yong, Min Sik\|Ryu, Jung Min\|Han, Ho Jae
PMID:	24738865

104.
Journal:	Eur J Cancer. 2014 Jul;50(11):1973-81.
Title:	RAC1b overexpression correlates with poor prognosis in KRAS/BRAF WT metastatic colorectal cancer patients treated with first-line FOLFOX/XELOX chemotherapy.
Author:	Alonso-Espinaco, Virginia\|Cuatrecasas, Miriam\|Alonso, Vicente\|Escudero, Pilar\|Marmol, Maribel\|Horndler, Carlos\|Ortego, Javier\|Gallego, Rosa\|Codony-Servat, Jordi\|Garcia-Albeniz, Xabier\|Jares, Pedro\|Castells, Antoni\|Lozano, Juan Jose\|Rosell, Rafael\|Maurel,
PMID:	24833563

105.
Journal:	Folia Biol (Praha). 2014;60(3):95-107.
Title:	Rho GTPase Rac1: molecular switch within the galectin network and for N-glycan alpha2,6-sialylation/O-glycan core 1 sialylation in colon cancer in vitro.
Author:	Andre, S\|Singh, T\|Lacal, J C\|Smetana, K Jr\|Gabius, H-J
PMID:	25056432

106.
Journal:	Nan Fang Yi Ke Da Xue Xue Bao. 2014 Jun;34(7):928-33.
Title:	[Construction of colorectal cancer cell line stably expressing mir-101 and identification of the target gene of mir-101].
Author:	Liu, Yan\|Lu, Yanxia\|Zhou, Min\|Zhang, Chao\|Li, Xuenong
PMID:	25057058

107.
Journal:	ScientificWorldJournal. 2014;2014:340271.
Title:	Radixin enhances colon cancer cell invasion by increasing MMP-7 production via Rac1-ERK pathway.
Author:	Jiang, Qi-Hong\|Wang, Ai-Xiang\|Chen, Yan
PMID:	25136657

108.
Journal:	Cancer Biomark. 2014;14(5):335-42.
Title:	Changes of cytoskeleton and cell cycle in Lovo cells via deletion of Rac1.
Author:	Nie, Fang\|Zhao, Shi-Yi\|Song, Fei-Xue\|Li, Pei-Wu
PMID:	25171475

109.
Journal:	J Cell Mol Med. 2015 Feb;19(2):383-95.
Title:	A novel synthetic small molecule YH-306 suppresses colorectal tumour growth and metastasis via FAK pathway.
Author:	Dai, Fujun\|Chen, Yihua\|Huang, Li\|Wang, Jinhua\|Zhang, Tao\|Li, Jingjie\|Tong, Weiguang\|Liu, Mingyao\|Yi, Zhengfang
PMID:	25351103

110.
Journal:	Cancer Lett. 2015 Jan 28;356(2 Pt B):669-75.
Title:	MicroRNA-320b promotes colorectal cancer proliferation and invasion by competing with its homologous microRNA-320a.
Author:	Zhou, Jiaojiao\|Zhang, Mengwen\|Huang, Yanqing\|Feng, Lin\|Chen, Hailong\|Hu, Yiwang\|Chen, Huarong\|Zhang, Kaitai\|Zheng, Lei\|Zheng, Shu
PMID:	25458952

111.
Journal:	Cancer Lett. 2015 Mar 1;358(1):76-84.
Title:	Semaphorin-3F suppresses the stemness of colorectal cancer cells by inactivating Rac1.
Author:	Rao, Jun\|Zhou, Zhi-Hang\|Yang, Jing\|Shi, Yu\|Xu, Sen-Lin\|Wang, Bin\|Ping, Yi-Fang\|Chen, Lu\|Cui, You-Hong\|Zhang, Xia\|Wu, Feng\|Bian, Xiu-Wu
PMID:	25529012

112.
Journal:	J Drug Target. 2015 May;23(4):380-6.
Title:	Gene silencing of Rac1 with RNA interference mediated by ultrasound and microbubbles in human LoVo cells: evaluation of cell invasion inhibition and metastatic.
Author:	Nie, Fang\|Wang, Xiao-Feng\|Zhao, Shi-Yi\|Bu, Lan\|Liu, Xue-Hui
PMID:	25673262

113.
Journal:	Oncogene. 2015 Dec 3;34(49):5971-82.
Title:	An EGFR/PI3K/AKT axis promotes accumulation of the Rac1-GEF Tiam1 that is critical in EGFR-driven tumorigenesis.
Author:	Zhu, G\|Fan, Z\|Ding, M\|Zhang, H\|Mu, L\|Ding, Y\|Zhang, Y\|Jia, B\|Chen, L\|Chang, Z\|Wu, W
PMID:	25746002

114.
Journal:	Cancer Cell Int. 2015 Apr 15;15:41.
Title:	RhoGDI2 up-regulates P-glycoprotein expression via Rac1 in gastric cancer cells.
Author:	Zheng, Zhong\|Liu, Bingya\|Wu, Xiaohua
PMID:	25901126

115.
Journal:	Am J Cancer Res. 2015 Jan 15;5(2):498-513. eCollection 2015.
Title:	ART1 promotes starvation-induced autophagy: a possible protective role in the development of colon carcinoma.
Author:	Tang, Yi\|Li, Ming\|Wang, Ya-Lan\|Threadgill, Michael D\|Xiao, Ming\|Mou, Chun-Feng\|Song, Guang-Lin\|Kuang, Jing\|Yang, Xi\|Yang, Li\|Gao, Xing-Jie\|Wang, Ya-Ping\|Meng, Yun-Peng
PMID:	25973293

116.
Journal:	Elife. 2015 Jun 30;4:e07091.
Title:	Daple is a novel non-receptor GEF required for trimeric G protein activation in Wnt signaling.
Author:	Aznar, Nicolas\|Midde, Krishna K\|Dunkel, Ying\|Lopez-Sanchez, Inmaculada\|Pavlova, Yelena\|Marivin, Arthur\|Barbazan, Jorge\|Murray, Fiona\|Nitsche, Ulrich\|Janssen, Klaus-Peter\|Willert, Karl\|Goel, Ajay\|Abal, Miguel\|Garcia-Marcos, Mikel\|Ghosh, Pradipta
PMID:	26126266

117.
Journal:	Nat Commun. 2015 Aug 3;6:7839.
Title:	Truncating mutation in the autophagy gene UVRAG confers oncogenic properties and chemosensitivity in colorectal cancers.
Author:	He, Shanshan\|Zhao, Zhen\|Yang, Yongfei\|O'Connell, Douglas\|Zhang, Xiaowei\|Oh, Soohwan\|Ma, Binyun\|Lee, Joo-Hyung\|Zhang, Tian\|Varghese, Bino\|Yip, Janae\|Dolatshahi Pirooz, Sara\|Li, Ming\|Zhang, Yong\|Li, Guo-Min\|Ellen Martin, Sue\|Machida, Keigo\|Liang, Chengyu
PMID:	26234763

118.
Journal:	J Cell Biol. 2015 Aug 31;210(5):817-32.
Title:	Hsc70 chaperone activity underlies Trio GEF function in axon growth and guidance induced by netrin-1.
Author:	DeGeer, Jonathan\|Kaplan, Andrew\|Mattar, Pierre\|Morabito, Morgane\|Stochaj, Ursula\|Kennedy, Timothy E\|Debant, Anne\|Cayouette, Michel\|Fournier, Alyson E\|Lamarche-Vane, Nathalie
PMID:	26323693

119.
Journal:	Cancer Lett. 2015 Dec 28;369(2):368-75.
Title:	Expression of tumor-related Rac1b antagonizes B-Raf-induced senescence in colorectal cells.
Author:	Henriques, Andreia F A\|Barros, Patricia\|Moyer, Mary Pat\|Matos, Paulo\|Jordan, Peter
PMID:	26341689

120.
Journal:	Int J Clin Exp Pathol. 2015 Sep 1;8(9):10534-44. eCollection 2015.
Title:	Down-regualtion of miR-106b induces epithelial-mesenchymal transition but suppresses metastatic colonization by targeting Prrx1 in colorectal cancer.
Author:	Zheng, Lin\|Zhang, Yuqin\|Lin, Shuimiao\|Sun, Aimin\|Chen, Runze\|Ding, Yi\|Ding, Yanqing
PMID:	26617763

121.
Journal:	Biol Cell. 2016 May;108(5):115-26.
Title:	Direct measurement of oscillatory RhoA activity in embryonic cortical neurons stimulated with the axon guidance cue netrin-1 using fluorescence resonance energy transfer.
Author:	Antoine-Bertrand, Judith\|Fu, Min\|Lamarche-Vane, Nathalie
PMID:	26787017

122.
Journal:	Genome Res. 2016 Apr;26(4):541-53.
Title:	A network-based analysis of colon cancer splicing changes reveals a tumorigenesis-favoring regulatory pathway emanating from ELK1.
Author:	Hollander, Dror\|Donyo, Maya\|Atias, Nir\|Mekahel, Keren\|Melamed, Zeev\|Yannai, Sivan\|Lev-Maor, Galit\|Shilo, Asaf\|Schwartz, Schraga\|Barshack, Iris\|Sharan, Roded\|Ast, Gil
PMID:	26860615

123.
Journal:	Oncotarget. 2016 Apr 5;7(14):17970-85.
Title:	Rac1b enhances cell survival through activation of the JNK2/c-JUN/Cyclin-D1 and AKT2/MCL1 pathways.
Author:	Li, Gang\|Ying, Li\|Wang, Hong\|Wei, Si-Si\|Chen, Jie\|Chen, Yi-He\|Xu, Wei-Ping\|Jie, Qi-Qiang\|Zhou, Qing\|Li, Yi-Gang\|Wei, Yi-Dong\|Wang, Yue-Peng
PMID:	26918455

124.
Journal:	Oncotarget. 2016 Jun 14;7(24):36168-36184.
Title:	SK3/TRPC1/Orai1 complex regulates SOCE-dependent colon cancer cell migration: a novel opportunity to modulate anti-EGFR mAb action by the alkyl-lipid Ohmline.
Author:	Gueguinou, Maxime\|Harnois, Thomas\|Crottes, David\|Uguen, Arnaud\|Deliot, Nadine\|Gambade, Audrey\|Chantome, Aurelie\|Haelters, Jean Pierre\|Jaffres, Paul Alain\|Jourdan, Marie Lise\|Weber, Gunther\|Soriani, Olivier\|Bougnoux, Philippe\|Mignen, Olivier\|Bourmeyster, N
PMID:	27102434

125.
Journal:	Cancer Res. 2016 Sep 1;76(17):5133-42.
Title:	The WASF3-NCKAP1-CYFIP1 Complex Is Essential for Breast Cancer Metastasis.
Author:	Teng, Yong\|Qin, Haiyan\|Bahassan, Abdulaziz\|Bendzunas, N George\|Kennedy, Eileen J\|Cowell, John K
PMID:	27432794

126.
Journal:	Autophagy. 2016 Dec;12(12):2498-2499.
Title:	Ivermectin induces PAK1-mediated cytostatic autophagy in breast cancer.
Author:	Wang, Kui\|Gao, Wei\|Dou, Qianhui\|Chen, Haining\|Li, Qifu\|Nice, Edouard C\|Huang, Canhua
PMID:	27657889

127.
Journal:	Eur J Clin Invest. 2016 Dec;46(12):1002-1011.
Title:	Rab11 collaborates E-cadherin to promote collective cell migration and indicates a poor prognosis in colorectal carcinoma.
Author:	Chung, Yuan-Chiang\|Wei, Wan-Chen\|Hung, Chia-Nung\|Kuo, Jen-Fang\|Hsu, Chih-Ping\|Chang, King-Jen\|Chao, Wei-Ting
PMID:	27696383

128.
Journal:	Oncotarget. 2016 Nov 22;7(47):77183-77195.
Title:	Blocking hepatic metastases of colon cancer cells using an shRNA against Rac1 delivered by activatable cell-penetrating peptide.
Author:	Bao, Ying\|Guo, Huihui\|Lu, Yongliang\|Feng, Wenming\|Sun, Xinrong\|Tang, Chengwu\|Wang, Xiang\|Shen, Mo
PMID:	27791203

129.
Journal:	Mol Carcinog. 2017 Jul;56(7):1743-1752.
Title:	Epigenetic silencing of diacylglycerol kinase gamma in colorectal cancer.
Author:	Kai, Masahiro\|Yamamoto, Eiichiro\|Sato, Akiko\|Yamano, Hiro-O\|Niinuma, Takeshi\|Kitajima, Hiroshi\|Harada, Taku\|Aoki, Hironori\|Maruyama, Reo\|Toyota, Mutsumi\|Hatahira, Tomo\|Nakase, Hiroshi\|Sugai, Tamotsu\|Yamashita, Toshiharu\|Toyota, Minoru\|Suzuki, Hiromu
PMID:	28218473

130.
Journal:	J Virol. 2017 Apr 28;91(10). pii: JVI.02191-16.
Title:	Measles Virus Enters Breast and Colon Cancer Cell Lines through a PVRL4-Mediated Macropinocytosis Pathway.
Author:	Delpeut, Sebastien\|Sisson, Gary\|Black, Karen M\|Richardson, Christopher D
PMID:	28250131

131.
Journal:	Oncotarget. 2017 Jul 4;8(27):44498-44510.
Title:	Cell type-dependent HIF1 alpha-mediated effects of hypoxia on proliferation, migration and metastatic potential of human tumor cells.
Author:	Tatrai, Eniko\|Bartal, Alexandra\|Gacs, Alexandra\|Paku, Sandor\|Kenessey, Istvan\|Garay, Tamas\|Hegedus, Balazs\|Molnar, Eszter\|Cserepes, Mihaly T\|Hegedus, Zita\|Kucsma, Nora\|Szakacs, Gergely\|Tovari, Jozsef
PMID:	28562340

132.
Journal:	J Biol Chem. 2017 Sep 8;292(36):14989-15001.
Title:	LGR5 receptor promotes cell-cell adhesion in stem cells and colon cancer cells via the IQGAP1-Rac1 pathway.
Author:	Carmon, Kendra S\|Gong, Xing\|Yi, Jing\|Wu, Ling\|Thomas, Anthony\|Moore, Catherine M\|Masuho, Ikuo\|Timson, David J\|Martemyanov, Kirill A\|Liu, Qingyun J
PMID:	28739799

133.
Journal:	Mol Cell Proteomics. 2017 Oct;16(10):1850-1863.
Title:	Identification of Differentially Expressed Splice Variants by the Proteogenomic Pipeline Splicify.
Author:	Komor, Malgorzata A\|Pham, Thang V\|Hiemstra, Annemieke C\|Piersma, Sander R\|Bolijn, Anne S\|Schelfhorst, Tim\|Delis-van Diemen, Pien M\|Tijssen, Marianne\|Sebra, Robert P\|Ashby, Meredith\|Meijer, Gerrit A\|Jimenez, Connie R\|Fijneman, Remond J A
PMID:	28747380

134.
Journal:	Biochim Biophys Acta Mol Cell Res. 2017 Dec;1864(12):2283-2296.
Title:	The ILK-MMP9-MRTF axis is crucial for EndMT differentiation of endothelial cells in a tumor microenvironment.
Author:	Ciszewski, Wojciech M\|Sobierajska, Katarzyna\|Wawro, Marta E\|Klopocka, Wanda\|Chefczynska, Natasza\|Muzyczuk, Angelika\|Siekacz, Kamil\|Wujkowska, Agata\|Niewiarowska, Jolanta
PMID:	28893556

135.
Journal:	Oncotarget. 2017 May 15;8(34):56659-56671.
Title:	PRPF overexpression induces drug resistance through actin cytoskeleton rearrangement and epithelial-mesenchymal transition.
Author:	Islam, Salman Ul\|Shehzad, Adeeb\|Sonn, Jong Kyung\|Lee, Young Sup
PMID:	28915620

136.
Journal:	Oncotarget. 2017 Nov 30;8(65):109632-109645.
Title:	LRP6 promotes invasion and metastasis of colorectal cancer through cytoskeleton dynamics.
Author:	Yao, Qian\|An, Yu\|Hou, Wei\|Cao, Ya-Nan\|Yao, Meng-Fei\|Ma, Ning-Ning\|Hou, Lin\|Zhang, Hong\|Liu, Hai-Jing\|Zhang, Bo
PMID:	29312635

137.
Journal:	Oncogene. 2018 Jan 4;37(1):8-17.
Title:	RCC2 is a novel p53 target in suppressing metastasis.
Author:	Song, C\|Liang, L\|Jin, Y\|Li, Y\|Liu, Y\|Guo, L\|Wu, C\|Yun, C-H\|Yin, Y
PMID:	28869598

138.
Journal:	Int J Mol Med. 2018 Mar;41(3):1397-1408.
Title:	shRNA-induced silencing of Ras-related C3 botulinum toxin substrate 1 inhibits the proliferation of colon cancer cells through upregulation of BAD and downregulation of cyclin D1.
Author:	Huang, You-Sheng\|Jie, Na\|Zhang, Yi-Xin\|Zou, Ke-Jian\|Weng, Yang
PMID:	29286138

139.
Journal:	J Biomed Mater Res A. 2018 Jun;106(6):1500-1510.
Title:	Carboxylated graphene oxide promoted axonal guidance growth by activating Netrin-1/deleted in colorectal cancer signaling in rat primary cultured cortical neurons.
Author:	Liu, Meili\|Jia, Zhengtai\|Xiao, Xiongfu\|Zhang, Zhifa\|Li, Ping\|Zhou, Gang\|Fan, Yubo
PMID:	29377591

140.
Journal:	Biochim Biophys Acta Mol Cell Res. 2018 Apr;1865(4):650-664.
Title:	Protein Kinase C-zeta stimulates colorectal cancer cell carcinogenesis via PKC-zeta/Rac1/Pak1/beta-Catenin signaling cascade.
Author:	Islam, S M Anisul\|Patel, Rekha\|Acevedo-Duncan, Mildred
PMID:	29408512

141.
Journal:	Biochem Pharmacol. 2018 Apr;150:191-201.
Title:	Natural small molecule bigelovin suppresses orthotopic colorectal tumor growth and inhibits colorectal cancer metastasis via IL6/STAT3 pathway.
Author:	Li, Mingyue\|Yue, Grace Gar-Lee\|Song, Li-Hua\|Huang, Mao-Bo\|Lee, Julia Kin-Ming\|Tsui, Stephen Kwok-Wing\|Fung, Kwok-Pui\|Tan, Ning-Hua\|Lau, Clara Bik-San
PMID:	29454618

142.
Journal:	Oncol Rep. 2018 May;39(5):2297-2305.
Title:	Delineating the underlying molecular mechanisms and key genes involved in metastasis of colorectal cancer via bioinformatics analysis.
Author:	Qi, Chao\|Chen, Yuanlei\|Zhou, Yixuan\|Huang, Xucheng\|Li, Guoli\|Zeng, Jin\|Ruan, Zhi\|Xie, Xinyou\|Zhang, Jun
PMID:	29517105

143.
Journal:	Cell Physiol Biochem. 2018;47(1):368-377.
Title:	The Epigenetic Factor KDM2B Regulates EMT and Small GTPases in Colon Tumor Cells.
Author:	Zacharopoulou, Nefeli\|Tsapara, Anna\|Kallergi, Galatea\|Schmid, Evi\|Alkahtani, Saad\|Alarifi, Saud\|Tsichlis, Philip N\|Kampranis, Sotirios C\|Stournaras, Christos
PMID:	29772566

144.
Journal:	Cell Death Dis. 2018 Jun 4;9(6):673.
Title:	Decreased expression of ARHGAP15 promotes the development of colorectal cancer through PTEN/AKT/FOXO1 axis.
Author:	Pan, Shengli\|Deng, Yingying\|Fu, Jun\|Zhang, Yuhao\|Zhang, Zhijin\|Ru, Xiaokun\|Qin, Xianju
PMID:	29867200

145.
Journal:	Lab Invest. 2018 Aug;98(8):989-998.
Title:	RAC1-GTP promotes epithelial-mesenchymal transition and invasion of colorectal cancer by activation of STAT3.
Author:	Zhou, Kai\|Rao, Jun\|Zhou, Zhi-Hua\|Yao, Xiao-Hong\|Wu, Feng\|Yang, Jing\|Yang, Lang\|Zhang, Xia\|Cui, You-Hong\|Bian, Xiu-Wu\|Shi, Yu\|Ping, Yi-Fang
PMID:	29884911

146.
Journal:	Anticancer Agents Med Chem. 2018 Jun 10. pii: ACAMC-EPUB-91045.
Title:	Verbascoside attenuates Rac-1 and HIF-1alpha signaling cascade in colorectal cancer cells.
Author:	Nabiuni, Mohammad\|Seyfi, Danial\|Behzad, Seyed Bahram\|Parivar, Kazem\|Tahmaseb, Mohammad\|Amini, Elaheh
PMID:	29886834

147.
Journal:	Technol Cancer Res Treat. 2018 Jan 1;17:1533033818790508.
Title:	MicroRNA-142-3p Promotes Cellular Invasion of Colorectal Cancer Cells by Activation of RAC1.
Author:	Gao, Xiang\|Xu, Wenhuan\|Lu, Tingxun\|Zhou, Jialiang\|Ge, Xiaosong\|Hua, Dong
PMID:	30064309