Primary Site >> Colorectal Cancer
Gene >> PXN
| 1. | |||||||||||
| Journal: | Lab Invest. 1996 Jan;74(1):199-208. | ||||||||||
| Title: | Formation of focal adhesion and spreading of polarized human colon cancer cells in association with tyrosine phosphorylation of paxillin in response to phorbol ester. | ||||||||||
| Author: | Sakamoto, M|Ino, Y|Ochiai, A|Kanai, Y|Akimoto, S|Hirohashi, S | ||||||||||
| PMID: | 8569182 | ||||||||||
| 2. | |||||||||||
| Journal: | Biochem Pharmacol. 2004 Jan 1;67(1):135-46. | ||||||||||
| Title: | Rapid tyrosine phosphorylation of focal adhesion kinase, paxillin, and p130Cas by gastrin in human colon cancer cells. | ||||||||||
| Author: | Yu, Hong-Gang|Schrader, Henning|Otte, Jan-Michel|Schmidt, Wolfgang E|Schmitz, Frank | ||||||||||
| PMID: | 14667936 | ||||||||||
| 3. | |||||||||||
| Journal: | Anticancer Res. 2004 Mar-Apr;24(2B):907-19. | ||||||||||
| Title: | Antitumor activity of imidazothioxanthones in murine and human tumor models in vitro and in vivo. | ||||||||||
| Author: | Varvaresou, A|Iakovou, K|Gikas, E|Fichtner, I|Fiebig, H H|Kelland, L R|Double, J A|Bibby, M C|Hendriks, H R | ||||||||||
| PMID: | 15161044 | ||||||||||
| 4. | |||||||||||
| Journal: | Cancer Biol Ther. 2007 Apr;6(4):494-503. | ||||||||||
| Title: | Profiling of selenomethionine responsive genes in colon cancer by microarray analysis. | ||||||||||
| Author: | Goulet, Anne-Christine|Watts, George|Lord, Jean L|Nelson, Mark A | ||||||||||
| PMID: | 17374985 | ||||||||||
| 5. | |||||||||||
| Journal: | Cell Mol Life Sci. 2008 May;65(9):1446-57. | ||||||||||
| Title: | Pressure activates colon cancer cell adhesion via paxillin phosphorylation, Crk, Cas, and Rac1. | ||||||||||
| Author: | Downey, C|Craig, D H|Basson, M D | ||||||||||
| PMID: | 18392556 | ||||||||||
| 6. | |||||||||||
| Journal: | Eur J Surg Oncol. 2008 Nov;34(11):1253-61. | ||||||||||
| Title: | Combined expression of the non-receptor protein tyrosine kinases FAK and Src in primary colorectal cancer is associated with tumor recurrence and metastasis formation. | ||||||||||
| Author: | de Heer, P|Koudijs, M M|van de Velde, C J H|Aalbers, R I J M|Tollenaar, R A E M|Putter, H|Morreau, J|van de Water, B|Kuppen, P J K | ||||||||||
| PMID: | 18556171 | ||||||||||
| 7. | |||||||||||
| Journal: | Cancer Invest. 2010 Feb;28(2):127-34. | ||||||||||
| Title: | Focal adhesion plaque associated cytoskeletons are involved in the invasion and metastasis of human colorectal carcinoma. | ||||||||||
| Author: | Yang, Hong-Jun|Chen, Juan-Zhi|Zhang, Wen-Li|Ding, Yan-Qing | ||||||||||
| PMID: | 19916745 | ||||||||||
| 8. | |||||||||||
| Journal: | Thromb Res. 2010 Jun;125(6):e323-8. | ||||||||||
| Title: | Coagulation Factor Xa inhibits cancer cell migration via LIMK1-mediated cofilin inactivation. | ||||||||||
| Author: | Borensztajn, Keren|Peppelenbosch, Maikel P|Spek, C Arnold | ||||||||||
| PMID: | 20347121 | ||||||||||
| 9. | |||||||||||
| Journal: | Hepatogastroenterology. 2011 Nov-Dec;58(112):1951-5. | ||||||||||
| Title: | Effects of paxillin on HCT-8 human colorectal cancer cells. | ||||||||||
| Author: | Jun, Qin|Zhiwei, Wang|Lilin, Ma|Jing, Ke|Qichao, Ni | ||||||||||
| PMID: | 21940355 | ||||||||||
| 10. | |||||||||||
| Journal: | Carcinogenesis. 2013 Apr;34(4):803-11. | ||||||||||
| Title: | Overexpression of paxillin induced by miR-137 suppression promotes tumor progression and metastasis in colorectal cancer. | ||||||||||
| Author: | Chen, Dong-Liang|Wang, De-Shen|Wu, Wen-Jing|Zeng, Zhao-Lei|Luo, Hui-Yan|Qiu, Miao-Zhen|Ren, Chao|Zhang, Dong-Sheng|Wang, Zhi-Qiang|Wang, Feng-Hua|Li, Yu-Hong|Kang, Tie-Bang|Xu, Rui-Hua | ||||||||||
| PMID: | 23275153 | ||||||||||
| 11. | |||||||||||
| Journal: | Oncotarget. 2015 Apr 20;6(11):8698-708. | ||||||||||
| Title: | Paxillin promotes colorectal tumor invasion and poor patient outcomes via ERK-mediated stabilization of Bcl-2 protein by phosphorylation at Serine 87. | ||||||||||
| Author: | Huang, Chi-Chou|Wu, De-Wei|Lin, Po-Lin|Lee, Huei | ||||||||||
| PMID: | 25826088 | ||||||||||
| 12. | |||||||||||
| Journal: | Med Sci Monit. 2015 Jul 10;21:1989-95. | ||||||||||
| Title: | Expression of Paxillin is Correlated with Clinical Prognosis in Colorectal Cancer Patients. | ||||||||||
| Author: | Zhao, Cheng-jin|Du, Shuang-kuan|Dang, Xing-bo|Gong, Min | ||||||||||
| PMID: | 26159303 | ||||||||||
| 13. | |||||||||||
| Journal: | Int J Clin Exp Pathol. 2015 Feb 1;8(2):1328-40. eCollection 2015. | ||||||||||
| Title: | MicroRNA-145 suppresses cell migration and invasion by targeting paxillin in human colorectal cancer cells. | ||||||||||
| Author: | Qin, Jun|Wang, Feiran|Jiang, Haiyan|Xu, Junfei|Jiang, Yasu|Wang, Zhiwei | ||||||||||
| PMID: | 25973017 | ||||||||||
| 14. | |||||||||||
| Journal: | J Biol Chem. 2015 Jun 12;290(24):15018-29. | ||||||||||
| Title: | Phosphatase and Tensin Homolog (PTEN) Represses Colon Cancer Progression through Inhibiting Paxillin Transcription via PI3K/AKT/NF-kappaB Pathway. | ||||||||||
| Author: | Zhang, Ling-Li|Mu, Gang-Gang|Ding, Qian-Shan|Li, Yan-Xia|Shi, Yun-bo|Dai, Jin-Fen|Yu, Hong-Gang | ||||||||||
| PMID: | 25873394 | ||||||||||
| 15. | |||||||||||
| Journal: | PLoS One. 2015 Apr 10;10(4):e0120616. | ||||||||||
| Title: | alpha-Actinin-4 enhances colorectal cancer cell invasion by suppressing focal adhesion maturation. | ||||||||||
| Author: | Fukumoto, Miki|Kurisu, Shusaku|Yamada, Tesshi|Takenawa, Tadaomi | ||||||||||
| PMID: | 25860875 | ||||||||||
| 16. | |||||||||||
| Journal: | Cell Death Differ. 2015 May;22(5):779-89. | ||||||||||
| Title: | Bcl-2 stabilization by paxillin confers 5-fluorouracil resistance in colorectal cancer. | ||||||||||
| Author: | Wu, D-W|Huang, C-C|Chang, S-W|Chen, T-H|Lee, H | ||||||||||
| PMID: | 25323586 | ||||||||||
| 17. | |||||||||||
| Journal: | Cancer Sci. 2016 Jan;107(1):28-35. | ||||||||||
| Title: | MicroRNA-27b suppresses tumor progression by regulating ARFGEF1 and focal adhesion signaling. | ||||||||||
| Author: | Matsuyama, Rei|Okuzaki, Daisuke|Okada, Masato|Oneyama, Chitose | ||||||||||
| PMID: | 26473412 | ||||||||||
| 18. | |||||||||||
| Journal: | Oncol Rep. 2016 Jan;35(1):409-17. | ||||||||||
| Title: | Paxillin is positively correlated with the clinicopathological factors of colorectal cancer, and knockdown of Paxillin improves sensitivity to cetuximab in colorectal cancer cells. | ||||||||||
| Author: | Du, Chuang|Wang, Xin|Zhang, Junling|Liu, Xiangzheng|Zhu, Jing|Liu, Yucun | ||||||||||
| PMID: | 26530439 | ||||||||||
| 19. | |||||||||||
| Journal: | Mol Pharmacol. 2016 May;89(5):521-40. | ||||||||||
| Title: | Targeting the Metastasis Suppressor, N-Myc Downstream Regulated Gene-1, with Novel Di-2-Pyridylketone Thiosemicarbazones: Suppression of Tumor Cell Migration and Cell-Collagen Adhesion by Inhibiting Focal Adhesion Kinase/Paxillin Signaling. | ||||||||||
| Author: | Wangpu, Xiongzhi|Lu, Jiaoyang|Xi, Ruxing|Yue, Fei|Sahni, Sumit|Park, Kyung Chan|Menezes, Sharleen|Huang, Michael L H|Zheng, Minhua|Kovacevic, Zaklina|Richardson, Des R | ||||||||||
| PMID: | 26895766 | ||||||||||
| 20. | |||||||||||
| Journal: | J BUON. 2017 Sep-Oct;22(5):1097-1106. | ||||||||||
| Title: | FAK, Src and p-Paxillin expression is decreased in liver metastasis of colorectal carcinoma patients. | ||||||||||
| Author: | Mantonakis, Eleftherios|Giaginis, Constantinos|Pikoulis, Emmanouel|Felekouras, Evangelos|Patsouris, Efstratios|Liakakos, Theodoros|Papalampros, Efstathios|Theocharis, Stamatios | ||||||||||
| PMID: | 29135089 | ||||||||||
| 21. | |||||||||||
| Journal: | Biol Chem. 2018 Jul 10. | ||||||||||
| Title: | Down-regulated paxillin suppresses cell proliferation and invasion by inhibiting M2 macrophage polarization in colon cancer. | ||||||||||
| Author: | Zhang, Ling-Li|Zhang, Lian-Feng|Shi, Yun-Bo | ||||||||||
| PMID: | 29924724 | ||||||||||
| 22. | |||||||||||
| Journal: | Genes Cells. 2018 Jul 2. | ||||||||||
| Title: | MicroRNA-137-mediated Src oncogenic signaling promotes cancer progression. | ||||||||||
| Author: | Kokuda, Rie|Watanabe, Risayo|Okuzaki, Daisuke|Akamatsu, Hiroki|Oneyama, Chitose | ||||||||||
| PMID: | 29962093 | ||||||||||