Primary Site >> Colorectal Cancer
Gene >> PXN
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Ref: Formation of focal adhesion and spreading of polarized human colon cancer cells in association with tyrosine phosphorylation of paxillin in response to phorbol ester. PMID: 8569182 |
Ref: Rapid tyrosine phosphorylation of focal adhesion kinase, paxillin, and p130Cas by gastrin in human colon cancer cells. PMID: 14667936 Ref: Antitumor activity of imidazothioxanthones in murine and human tumor models in vitro and in vivo. PMID: 15161044 |
Ref: Profiling of selenomethionine responsive genes in colon cancer by microarray analysis. PMID: 17374985 |
Ref: Pressure activates colon cancer cell adhesion via paxillin phosphorylation, Crk, Cas, and Rac1. PMID: 18392556 Ref: Combined expression of the non-receptor protein tyrosine kinases FAK and Src in primary colorectal cancer is associated with tumor recurrence and metastasis formation. PMID: 18556171 |
Ref: Focal adhesion plaque associated cytoskeletons are involved in the invasion and metastasis of human colorectal carcinoma. PMID: 19916745 Ref: Coagulation Factor Xa inhibits cancer cell migration via LIMK1-mediated cofilin inactivation. PMID: 20347121 |
Ref: Effects of paxillin on HCT-8 human colorectal cancer cells. PMID: 21940355 |
Ref: Overexpression of paxillin induced by miR-137 suppression promotes tumor progression and metastasis in colorectal cancer. PMID: 23275153 |
Ref: Bcl-2 stabilization by paxillin confers 5-fluorouracil resistance in colorectal cancer. PMID: 25323586 Ref: Paxillin promotes colorectal tumor invasion and poor patient outcomes via ERK-mediated stabilization of Bcl-2 protein by phosphorylation at Serine 87. PMID: 25826088 Ref: alpha-Actinin-4 enhances colorectal cancer cell invasion by suppressing focal adhesion maturation. PMID: 25860875 Ref: Phosphatase and Tensin Homolog (PTEN) Represses Colon Cancer Progression through Inhibiting Paxillin Transcription via PI3K/AKT/NF-kappaB Pathway. PMID: 25873394 Ref: MicroRNA-145 suppresses cell migration and invasion by targeting paxillin in human colorectal cancer cells. PMID: 25973017 Ref: Expression of Paxillin is Correlated with Clinical Prognosis in Colorectal Cancer Patients. PMID: 26159303 |
Ref: MicroRNA-27b suppresses tumor progression by regulating ARFGEF1 and focal adhesion signaling. PMID: 26473412 Ref: Paxillin is positively correlated with the clinicopathological factors of colorectal cancer, and knockdown of Paxillin improves sensitivity to cetuximab in colorectal cancer cells. PMID: 26530439 Ref: Targeting the Metastasis Suppressor, N-Myc Downstream Regulated Gene-1, with Novel Di-2-Pyridylketone Thiosemicarbazones: Suppression of Tumor Cell Migration and Cell-Collagen Adhesion by Inhibiting Focal Adhesion Kinase/Paxillin Signaling. PMID: 26895766 |
Ref: FAK, Src and p-Paxillin expression is decreased in liver metastasis of colorectal carcinoma patients. PMID: 29135089 |
Ref: Down-regulated paxillin suppresses cell proliferation and invasion by inhibiting M2 macrophage polarization in colon cancer. PMID: 29924724 Ref: MicroRNA-137-mediated Src oncogenic signaling promotes cancer progression. PMID: 29962093 |