Primary Site >> Colorectal Cancer

Gene >> PTTG1

Journal: Lancet. 2000 Feb 26;355(9205):716-9.
Title: Expression of pituitary-tumour transforming gene in colorectal tumours.
Author: Heaney, A P|Singson, R|McCabe, C J|Nelson, V|Nakashima, M|Melmed, S
PMID: 10703804
Journal: J Clin Endocrinol Metab. 2001 Oct;86(10):5025-32.
Title: Transforming events in thyroid tumorigenesis and their association with follicular lesions.
Author: Heaney, A P|Nelson, V|Fernando, M|Horwitz, G
PMID: 11600580
Journal: J Clin Endocrinol Metab. 2003 May;88(5):2341-7.
Title: Pituitary tumor transforming gene and fibroblast growth factor-2 expression: potential prognostic indicators in differentiated thyroid cancer.
Author: Boelaert, K|McCabe, C J|Tannahill, L A|Gittoes, N J L|Holder, R L|Watkinson, J C|Bradwell, A R|Sheppard, M C|Franklyn, J A
PMID: 12727994
Journal: J Biol Chem. 2004 May 14;279(20):21183-92.
Title: p53-regulated transcriptional program associated with genotoxic stress-induced apoptosis.
Author: Kho, Patricia S|Wang, Zhen|Zhuang, Li|Li, Yuqing|Chew, Joon-Lin|Ng, Huck-Hui|Liu, Edison T|Yu, Qiang
PMID: 15016801
Journal: Mol Pharmacol. 2006 Jan;69(1):154-64.
Title: The blockage of survivin and securin expression increases the cytochalasin B-induced cell death and growth inhibition in human cancer cells.
Author: Chao, Jui-I|Liu, Huei-Fang
PMID: 16219911
Journal: Hepatology. 2006 May;43(5):1042-52.
Title: Adenovirus-mediated transfer of siRNA against PTTG1 inhibits liver cancer cell growth in vitro and in vivo.
Author: Cho-Rok, Jung|Yoo, Jinsang|Jang, Ye Jin|Kim, Sangsoo|Chu, In-Sun|Yeom, Young Il|Choi, Jong Young|Im, Dong-Soo
PMID: 16628636
Journal: Br J Cancer. 2006 Jun 5;94(11):1672-7.
Title: Securin (hPTTG1) expression is regulated by beta-catenin/TCF in human colorectal carcinoma.
Author: Hlubek, F|Pfeiffer, S|Budczies, J|Spaderna, S|Jung, A|Kirchner, T|Brabletz, T
PMID: 16705313
Journal: Clin Med Res. 2006 Jun;4(2):130-7.
Title: The emerging role of pituitary tumor transforming gene in tumorigenesis.
Author: Tfelt-Hansen, Jacob|Kanuparthi, Deepthi|Chattopadhyay, Naibedya
PMID: 16809406
Journal: Toxicol Lett. 2006 Dec 1;167(2):122-30.
Title: Opposing securin and p53 protein expression in the oxaliplatin-induced cytotoxicity of human colorectal cancer cells.
Author: Chiu, Shu-Jun|Hsu, Tzu-Sheng|Chao, Jui-I
PMID: 17045763
Journal: Anticancer Res. 2006 Nov-Dec;26(6C):4745-51.
Title: Biochemical and clinical approaches in evaluating the prognosis of colon cancer.
Author: Talvinen, Kati|Tuikkala, Johannes|Gronroos, Juha|Huhtinen, Heikki|Kronqvist, Pauliina|Aittokallio, Tero|Nevalainen, Olli|Hiekkanen, Heikki|Nevalainen, Timo|Sundstrom, Jari
PMID: 17214335
Journal: Chem Biol Interact. 2007 Dec 15;170(3):153-61.
Title: Expression of securin promotes colorectal cancer cell death via a p53-independent pathway after radiation.
Author: Chiu, Shu-Jun|Hsu, Tzu-Sheng|Chao, Jui-I
PMID: 17854787
Journal: Carcinogenesis. 2007 Mar;28(3):749-59.
Title: Securin induces genetic instability in colorectal cancer by inhibiting double-stranded DNA repair activity.
Author: Kim, D S|Franklyn, J A|Smith, V E|Stratford, A L|Pemberton, H N|Warfield, A|Watkinson, J C|Ishmail, T|Wakelam, M J O|McCabe, C J
PMID: 17071631
Journal: Dan Med Bull. 2008 Feb;55(1):17-46.
Title: The role of calcium-sensing receptor and signalling pathways in the pathophysiology in two in vitro models of malignant hypercalcemia: the rat rice H-500 Leydig testis cancer and prostate cancer (PC-3) cells. Expression and regulation of pituitary tumor t
Author: Tfelt-Hansen, Jacob
PMID: 18321443
Journal: BMC Cancer. 2008 Apr 21;8:110.
Title: Methylation alterations are not a major cause of PTTG1 misregulation.
Author: Hidalgo, Manuel|Galan, Jose Jorge|Saez, Carmen|Ferrero, Eduardo|Castilla, Carolina|Ramirez-Lorca, Reposo|Pelaez, Pablo|Ruiz, Agustin|Japon, Miguel A|Royo, Jose Luis
PMID: 18426563
Journal: Toxicol Lett. 2008 Jun 30;179(2):63-70.
Title: Regulation of gamma-H2AX and securin contribute to apoptosis by oxaliplatin via a p38 mitogen-activated protein kinase-dependent pathway in human colorectal cancer cells.
Author: Chiu, Shu-Jun|Chao, Jui-I|Lee, Yi-Jang|Hsu, Tzu-Sheng
PMID: 18499365
Journal: Chem Biol Interact. 2008 Oct 22;176(1):48-57.
Title: Celecoxib induces p53-PUMA pathway for apoptosis in human colorectal cancer cells.
Author: Liu, Huei-Fang|Hsiao, Po-Wen|Chao, Jui-I
PMID: 18760266
Journal: Ai Zheng. 2008 Nov;27(11):1217-21.
Title: [Expression of human pituitary tumor transforming gene 1 in colorectal cancer detected with real-time fluorescent quantitative PCR and its clinical significance].
Author: Wu, Bin-Wen|Ma, Dong|Li, Dong-Feng|Li, You-Jia|Deng, Gang|Zeng, Zhi-Gang|Zhang, Kai-Jun|Zhang, Ying-Hua|Geng, Qing-Shan
PMID: 19000457
Journal: Nutr Cancer. 2010;62(6):825-40.
Title: Hydrophobic bile acid-induced micronuclei formation, mitotic perturbations, and decreases in spindle checkpoint proteins: relevance to genomic instability in colon carcinogenesis.
Author: Payne, Claire M|Crowley-Skillicorn, Cheray|Bernstein, Carol|Holubec, Hana|Moyer, Mary Pat|Bernstein, Harris
PMID: 20661832
Journal: Acta Oncol. 2011 Nov;50(8):1158-66.
Title: Securin identifies a subgroup of patients with poor outcome in rectal cancer treated with long-course (chemo)radiotherapy.
Author: Avoranta, S Tuulia|Korkeila, Eija A|Minn, Heikki R I|Syrjanen, Kari J|Pyrhonen, Seppo O|Sundstrom, Jari T T
PMID: 22023115
Journal: Oncol Rep. 2011 May;25(5):1321-7.
Title: RNA expression of the molecular signature genes for metastasis in colorectal cancer.
Author: Carvalho, Luciano|Yu, Jinsheng|Schwartsmann, Gilberto|McLeod, Howard L|Fleshman, James W
PMID: 21380492
Journal: Cancer Lett. 2011 Jan 1;300(1):96-104.
Title: Securin depletion sensitizes human colon cancer cells to fisetin-induced apoptosis.
Author: Yu, Sz-Hsien|Yang, Pei-Ming|Peng, Chih-Wen|Yu, Yi-Chu|Chiu, Shu-Jun
PMID: 20974518
Journal: PLoS One. 2011;6(8):e23754.
Title: PTTG1 attenuates drug-induced cellular senescence.
Author: Tong, Yunguang|Zhao, Weijiang|Zhou, Cuiqi|Wawrowsky, Kolja|Melmed, Shlomo
PMID: 21858218
Journal: PLoS One. 2012;7(4):e36006.
Title: Securin enhances the anti-cancer effects of 6-methoxy-3-(3',4',5'-trimethoxy-benzoyl)-1H-indole (BPR0L075) in human colorectal cancer cells.
Author: Tseng, Ho-Hsing|Chuah, Qiu-Yu|Yang, Pei-Ming|Chen, Chiung-Tong|Chao, Jung-Chi|Lin, Ming-Der|Chiu, Shu-Jun
PMID: 22563433
Journal: Chem Biol Interact. 2013 Apr 25;203(2):412-22.
Title: Evidence of securin-mediated resistance to gefitinib-induced apoptosis in human cancer cells.
Author: Yu, Sheng-Yi|Liu, Huei-Fang|Wang, Su-Pei|Chang, Chia-Ching|Tsai, Chuan-Mei|Chao, Jui-I
PMID: 23523951
Journal: Oncogene. 2014 Feb 13;33(7):851-61.
Title: PTTG acts as a STAT3 target gene for colorectal cancer cell growth and motility.
Author: Zhou, C|Tong, Y|Wawrowsky, K|Melmed, S
PMID: 23416975
Journal: Chem Biol Interact. 2014 Sep 5;220:41-50.
Title: The depletion of securin enhances butein-induced apoptosis and tumor inhibition in human colorectal cancer.
Author: Huang, Yu-Tin|Lin, Chien-I|Chien, Pei-Hsuan|Tang, Tsai-Tai|Lin, Johnson|Chao, Jui-I
PMID: 24931875
Journal: BMC Med Genomics. 2015 Aug 12;8:49.
Title: FoxM1 transactivates PTTG1 and promotes colorectal cancer cell migration and invasion.
Author: Zheng, Yun|Guo, Jinjun|Zhou, Jin|Lu, Jinjian|Chen, Qi|Zhang, Cui|Qing, Chen|Koeffler, H Philip|Tong, Yunguang
PMID: 26264222
Journal: Int J Clin Exp Med. 2015 Dec 15;8(12):22149-57. eCollection 2015.
Title: Roles of miR-186 and PTTG1 in colorectal neuroendocrine tumors.
Author: Wang, Maonan|Xia, Xin|Chu, Wenxiang|Xia, Liyan|Meng, Tao|Liu, Lintao|Liu, Yushi
PMID: 26885189
Journal: Oncol Lett. 2016 Dec;12(6):4975-4982.
Title: Combining fisetin and ionizing radiation suppresses the growth of mammalian colorectal cancers in xenograft tumor models.
Author: Leu, Jyh-Der|Wang, Bo-Shen|Chiu, Shu-Jun|Chang, Chun-Yuan|Chen, Chien-Chih|Chen, Fu-Du|Avirmed, Shiirevnyamba|Lee, Yi-Jang
PMID: 28105204
Journal: Mol Carcinog. 2016 Jan;55(1):15-26.
Title: The proto-oncogene PBF binds p53 and is associated with prognostic features in colorectal cancer.
Author: Read, Martin L|Seed, Robert I|Modasia, Bhavika|Kwan, Perkin P K|Sharma, Neil|Smith, Vicki E|Watkins, Rachel J|Bansal, Sukhchain|Gagliano, Teresa|Stratford, Anna L|Ismail, Tariq|Wakelam, Michael J O|Kim, Dae S|Ward, Stephen T|Boelaert, Kristien|Franklyn, J
PMID: 25408419
Journal: J Pathol. 2017 Jan;241(1):67-79.
Title: MIIP haploinsufficiency induces chromosomal instability and promotes tumour progression in colorectal cancer.
Author: Sun, Yan|Ji, Ping|Chen, Tao|Zhou, Xinhui|Yang, Da|Guo, Yuhong|Liu, Yuexin|Hu, Limei|Xia, Dianren|Liu, Yanxue|Multani, Asha S|Shmulevich, Ilya|Kucherlapati, Raju|Kopetz, Scott|Sood, Anil K|Hamilton, Stanley R|Sun, Baocun|Zhang, Wei
PMID: 27741356
Journal: Biomed Pharmacother. 2017 May;89:108-115.
Title: The clinical value and biological function of PTTG1 in colorectal cancer.
Author: Ren, Qinggui|Jin, Bingwei
PMID: 28219049
Journal: Chem Biodivers. 2017 May 6.
Title: Systematic Identification and Competitive Disruption of Securin-Binding Partners in the Gene Diversity Space of Human Colorectal Cancer.
Author: Zhang, Yinguang|Zhang, Yongwang|Zhang, Yuxiang
PMID: 28477416
Journal: J Surg Res. 2017 Dec;220:427-437.
Title: Optimization of a multigene biochip for detection of relapsed and early relapsed colorectal cancer.
Author: Chang, Yu-Tang|Yeh, Yung-Sung|Ma, Cheng-Jen|Huang, Ching-Wen|Tsai, Hsiang-Lin|Huang, Ming-Yii|Cheng, Tian-Lu|Wang, Jaw-Yuan
PMID: 28711367
Journal: Ann Coloproctol. 2017 Aug;33(4):139-145.
Title: Anaphase-Promoting Complex 7 is a Prognostic Factor in Human Colorectal Cancer.
Author: Kim, Ik Yong|Kwon, Hye Yeon|Park, Kwang Hwa|Kim, Dae Sung
PMID: 28932723
Journal: Mol Cell Probes. 2018 Feb;37:39-47.
Title: Identification of genes involved in the four stages of colorectal cancer: Gene expression profiling.
Author: Shi, Guiling|Wang, Yijia|Zhang, Chunze|Zhao, Zhenying|Sun, Xiuying|Zhang, Shiwu|Fan, Jinling|Zhou, Cunxia|Zhang, Jihong|Zhang, Huijuan|Liu, Jun
PMID: 29179987
Journal: Am J Cancer Res. 2018 Feb 1;8(2):245-255. eCollection 2018.
Title: Long noncoding RNA CCAT2 is activated by E2F1 and exerts oncogenic properties by interacting with PTTG1 in pituitary adenomas.
Author: Fu, Dongxia|Zhang, Yunna|Cui, Haibin
PMID: 29511595
Journal: Oncogene. 2018 Oct 22. pii: 10.1038/s41388-018-0547-y.
Title: Targeting colon cancer with the novel STAT3 inhibitor bruceantinol.
Author: Wei, Ning|Li, Jun|Fang, Cheng|Chang, Jin|Xirou, Vasiliki|Syrigos, Nick K|Marks, Benjamin J|Chu, Edward|Schmitz, John C
PMID: 30348989