Primary Site >> Colorectal Cancer
Gene >> PTTG1
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Ref: Expression of pituitary-tumour transforming gene in colorectal tumours. PMID: 10703804 |
Ref: Transforming events in thyroid tumorigenesis and their association with follicular lesions. PMID: 11600580 |
Ref: Pituitary tumor transforming gene and fibroblast growth factor-2 expression: potential prognostic indicators in differentiated thyroid cancer. PMID: 12727994 |
Ref: p53-regulated transcriptional program associated with genotoxic stress-induced apoptosis. PMID: 15016801 |
Ref: The blockage of survivin and securin expression increases the cytochalasin B-induced cell death and growth inhibition in human cancer cells. PMID: 16219911 Ref: Adenovirus-mediated transfer of siRNA against PTTG1 inhibits liver cancer cell growth in vitro and in vivo. PMID: 16628636 Ref: Securin (hPTTG1) expression is regulated by beta-catenin/TCF in human colorectal carcinoma. PMID: 16705313 Ref: The emerging role of pituitary tumor transforming gene in tumorigenesis. PMID: 16809406 Ref: Opposing securin and p53 protein expression in the oxaliplatin-induced cytotoxicity of human colorectal cancer cells. PMID: 17045763 Ref: Biochemical and clinical approaches in evaluating the prognosis of colon cancer. PMID: 17214335 |
Ref: Securin induces genetic instability in colorectal cancer by inhibiting double-stranded DNA repair activity. PMID: 17071631 Ref: Expression of securin promotes colorectal cancer cell death via a p53-independent pathway after radiation. PMID: 17854787 |
Ref: The role of calcium-sensing receptor and signalling pathways in the pathophysiology in two in vitro models of malignant hypercalcemia: the rat rice H-500 Leydig testis cancer and prostate cancer (PC-3) cells. Expression and regulation of pituitary tumor t PMID: 18321443 Ref: Methylation alterations are not a major cause of PTTG1 misregulation. PMID: 18426563 Ref: Regulation of gamma-H2AX and securin contribute to apoptosis by oxaliplatin via a p38 mitogen-activated protein kinase-dependent pathway in human colorectal cancer cells. PMID: 18499365 Ref: Celecoxib induces p53-PUMA pathway for apoptosis in human colorectal cancer cells. PMID: 18760266 Ref: [Expression of human pituitary tumor transforming gene 1 in colorectal cancer detected with real-time fluorescent quantitative PCR and its clinical significance]. PMID: 19000457 |
Ref: Hydrophobic bile acid-induced micronuclei formation, mitotic perturbations, and decreases in spindle checkpoint proteins: relevance to genomic instability in colon carcinogenesis. PMID: 20661832 |
Ref: Securin depletion sensitizes human colon cancer cells to fisetin-induced apoptosis. PMID: 20974518 Ref: RNA expression of the molecular signature genes for metastasis in colorectal cancer. PMID: 21380492 Ref: PTTG1 attenuates drug-induced cellular senescence. PMID: 21858218 Ref: Securin identifies a subgroup of patients with poor outcome in rectal cancer treated with long-course (chemo)radiotherapy. PMID: 22023115 |
Ref: Securin enhances the anti-cancer effects of 6-methoxy-3-(3',4',5'-trimethoxy-benzoyl)-1H-indole (BPR0L075) in human colorectal cancer cells. PMID: 22563433 |
Ref: Evidence of securin-mediated resistance to gefitinib-induced apoptosis in human cancer cells. PMID: 23523951 |
Ref: PTTG acts as a STAT3 target gene for colorectal cancer cell growth and motility. PMID: 23416975 Ref: The depletion of securin enhances butein-induced apoptosis and tumor inhibition in human colorectal cancer. PMID: 24931875 |
Ref: FoxM1 transactivates PTTG1 and promotes colorectal cancer cell migration and invasion. PMID: 26264222 Ref: Roles of miR-186 and PTTG1 in colorectal neuroendocrine tumors. PMID: 26885189 |
Ref: The proto-oncogene PBF binds p53 and is associated with prognostic features in colorectal cancer. PMID: 25408419 Ref: Combining fisetin and ionizing radiation suppresses the growth of mammalian colorectal cancers in xenograft tumor models. PMID: 28105204 |
Ref: MIIP haploinsufficiency induces chromosomal instability and promotes tumour progression in colorectal cancer. PMID: 27741356 Ref: The clinical value and biological function of PTTG1 in colorectal cancer. PMID: 28219049 Ref: Systematic Identification and Competitive Disruption of Securin-Binding Partners in the Gene Diversity Space of Human Colorectal Cancer. PMID: 28477416 Ref: Optimization of a multigene biochip for detection of relapsed and early relapsed colorectal cancer. PMID: 28711367 Ref: Anaphase-Promoting Complex 7 is a Prognostic Factor in Human Colorectal Cancer. PMID: 28932723 |
Ref: Identification of genes involved in the four stages of colorectal cancer: Gene expression profiling. PMID: 29179987 Ref: Long noncoding RNA CCAT2 is activated by E2F1 and exerts oncogenic properties by interacting with PTTG1 in pituitary adenomas. PMID: 29511595 Ref: Targeting colon cancer with the novel STAT3 inhibitor bruceantinol. PMID: 30348989 |