Primary Site >> Colorectal Cancer

Gene >> PTPN6

Journal: Gene. 2003 Mar 13;306:1-12.
Title: The function of the protein tyrosine phosphatase SHP-1 in cancer.
Author: Wu, Chengyu|Sun, Mingzhong|Liu, Lijun|Zhou, G Wayne
PMID: 12657462
Journal: J Cell Mol Med. 2009 Sep;13(9B):3668-79.
Title: Inhibition of DNA methyltransferase induces G2 cell cycle arrest and apoptosis in human colorectal cancer cells via inhibition of JAK2/STAT3/STAT5 signalling.
Author: Xiong, Hua|Chen, Zhao-Fei|Liang, Qin-Chuan|Du, Wan|Chen, Hui-Min|Su, Wen-Yu|Chen, Guo-Qiang|Han, Ze-Guang|Fang, Jing-Yuan
PMID: 20196786
Journal: J Immunol. 2010 Jun 1;184(11):6529-36.
Title: Novel SHP-1 inhibitors tyrosine phosphatase inhibitor-1 and analogs with preclinical anti-tumor activities as tolerated oral agents.
Author: Kundu, Suman|Fan, Keke|Cao, Mingli|Lindner, Daniel J|Zhao, Zhizhaung Joe|Borden, Ernest|Yi, Taolin
PMID: 20421638
Journal: Mol Carcinog. 2012 Feb;51(2):174-84.
Title: Trichostatin A, a histone deacetylase inhibitor, suppresses JAK2/STAT3 signaling via inducing the promoter-associated histone acetylation of SOCS1 and SOCS3 in human colorectal cancer cells.
Author: Xiong, Hua|Du, Wan|Zhang, Yan-Jie|Hong, Jie|Su, Wen-Yu|Tang, Jie-Ting|Wang, Ying-Chao|Lu, Rong|Fang, Jing-Yuan
PMID: 21520296
Journal: Asian Pac J Cancer Prev. 2016;17(8):4117-23.
Title: Epithelial-Specific SHP1-P2 Methylation - a Novel Universal Tumor Marker for Detection of Colorectal Cancer Lymph Node Metastasis.
Author: Rattanatanyong, Prakasit|Keelawat, Somboon|Kitkumthorn, Nakarin|Mutirangura, Apiwat
PMID: 27644671
Journal: Oncotarget. 2017 Apr 11;8(15):24762-24776.
Title: The oncoprotein gankyrin promotes the development of colitis-associated cancer through activation of STAT3.
Author: Sakurai, Toshiharu|Higashitsuji, Hiroaki|Kashida, Hiroshi|Watanabe, Tomohiro|Komeda, Yoriaki|Nagai, Tomoyuki|Hagiwara, Satoru|Kitano, Masayuki|Nishida, Naoshi|Abe, Takaya|Kiyonari, Hiroshi|Itoh, Katsuhiko|Fujita, Jun|Kudo, Masatoshi
PMID: 28160571
Journal: Clin Cancer Res. 2018 Mar 15;24(6):1473-1485.
Title: RING-Finger Protein 6 Amplification Activates JAK/STAT3 Pathway by Modifying SHP-1 Ubiquitylation and Associates with Poor Outcome in Colorectal Cancer.
Author: Liang, Qian|Ma, Dan|Zhu, Xiaoqiang|Wang, Zhenhua|Sun, Tian-Tian|Shen, Chaoqin|Yan, Tingting|Tian, Xianglong|Yu, TaChung|Guo, Fangfang|Tang, JiaYin|Lin, Yanwei|Chen, Huimin|Zhou, Chao|Ge, Zhizheng|Zhong, Ming|Chen, Jinxian|Liu, Qiang|Wang, Zheng|Fang, Jing
PMID: 29288235
Journal: Int J Mol Med. 2018 Jul;42(1):368-380.
Title: Inflammatory genes are novel prognostic biomarkers for colorectal cancer.
Author: Jiang, Hao|Dong, Li|Gong, Fangyan|Gu, Yuping|Zhang, Henghun|Fan, Dong|Sun, Zhiguo
PMID: 29693170