Primary Site >> Stomach Cancer
Gene >> PTPN11
| 1. | |||||||||||
| Journal: | Oncol Rep. 1995 Sep;2(5):819-23. | ||||||||||
| Title: | Increased expression and phosphorylation of sh-ptp2 (syp) in human gastric carcinomas. | ||||||||||
| Author: | Kitahara, K|Yasui, W|Kuniyasu, H|Yokozaki, H|Yunotani, S|Hisatsugu, T|Tahara, E | ||||||||||
| PMID: | 21597824 | ||||||||||
| 2. | |||||||||||
| Journal: | Microbes Infect. 2003 Feb;5(2):143-50. | ||||||||||
| Title: | Helicobacter pylori CagA--a potential bacterial oncoprotein that functionally mimics the mammalian Gab family of adaptor proteins. | ||||||||||
| Author: | Hatakeyama, Masanori | ||||||||||
| PMID: | 12650772 | ||||||||||
| 3. | |||||||||||
| Journal: | Gastroenterology. 2004 Jan;126(1):196-207. | ||||||||||
| Title: | Gastric cancer development in mice lacking the SHP2 binding site on the IL-6 family co-receptor gp130. | ||||||||||
| Author: | Judd, Louise M|Alderman, Barbara M|Howlett, Meegan|Shulkes, Arthur|Dow, Chris|Moverley, Jill|Grail, Diane|Jenkins, Brendan J|Ernst, Matthias|Giraud, Andrew S | ||||||||||
| PMID: | 14699500 | ||||||||||
| 4. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2005 Jun 17;331(4):984-92. | ||||||||||
| Title: | Leptin activates STAT and ERK2 pathways and induces gastric cancer cell proliferation. | ||||||||||
| Author: | Pai, Rama|Lin, Cal|Tran, Teresa|Tarnawski, Andrzej | ||||||||||
| PMID: | 15882975 | ||||||||||
| 5. | |||||||||||
| Journal: | Int J Cancer. 2006 Jan 1;118(1):203-8. | ||||||||||
| Title: | Association between serum pepsinogens and polymorphismof PTPN11 encoding SHP-2 among Helicobacter pylori seropositive Japanese. | ||||||||||
| Author: | Goto, Yasuyuki|Ando, Takafumi|Yamamoto, Kazuhito|Tamakoshi, Akiko|El-Omar, Emad|Goto, Hidemi|Hamajima, Nobuyuki | ||||||||||
| PMID: | 16032704 | ||||||||||
| 6. | |||||||||||
| Journal: | Int J Oncol. 2006 Jul;29(1):163-8. | ||||||||||
| Title: | FGF signaling network in the gastrointestinal tract (review). | ||||||||||
| Author: | Katoh, Masuko|Katoh, Masaru | ||||||||||
| PMID: | 16773196 | ||||||||||
| 7. | |||||||||||
| Journal: | Cancer Sci. 2006 Nov;97(11):1129-38. | ||||||||||
| Title: | Genetic factors involved in the development of Helicobacter pylori-related gastric cancer. | ||||||||||
| Author: | Hamajima, Nobuyuki|Naito, Mariko|Kondo, Takaaki|Goto, Yasuyuki | ||||||||||
| PMID: | 16879717 | ||||||||||
| 8. | |||||||||||
| Journal: | Int J Med Sci. 2006 Nov 1;4(1):1-6. | ||||||||||
| Title: | Grb2-associated binder 1 polymorphism was associated with the risk of Helicobactor pylori infection and gastric atrophy. | ||||||||||
| Author: | Goto, Yasuyuki|Ando, Takafumi|Nishio, Kazuko|Kawai, Sayo|Ishida, Yoshiko|Naito, Mariko|Goto, Hidemi|Hamajima, Nobuyuki | ||||||||||
| PMID: | 17211494 | ||||||||||
| 9. | |||||||||||
| Journal: | Gastric Cancer. 2006;9(4):277-83. Epub 2006 Nov 24. | ||||||||||
| Title: | Significant association between PTPN11 polymorphism and gastric atrophy among Japanese Brazilians. | ||||||||||
| Author: | Kawai, Sayo|Goto, Yasuyuki|Ito, Lucy S|Oba-Shinjo, Sueli M|Uno, Miyuki|Shinjo, Samuel K|Marie, Suely K N|Ishida, Yoshiko|Nishio, Kazuko|Naito, Mariko|Hamajima, Nobuyuki | ||||||||||
| PMID: | 17235629 | ||||||||||
| 10. | |||||||||||
| Journal: | Cancer Biol Ther. 2007 Jun;6(6):832-9. Epub 2007 Mar 26. | ||||||||||
| Title: | Dysregulation of stem cell signaling network due to germline mutation, SNP, Helicobacter pylori infection, epigenetic change and genetic alteration in gastric cancer. | ||||||||||
| Author: | Katoh, Masaru | ||||||||||
| PMID: | 17568183 | ||||||||||
| 11. | |||||||||||
| Journal: | BMC Gastroenterol. 2009 Jul 9;9:51. | ||||||||||
| Title: | Associations of a PTPN11 G/A polymorphism at intron 3 with Helicobactor pylori seropositivity, gastric atrophy and gastric cancer in Japanese. | ||||||||||
| Author: | Hishida, Asahi|Matsuo, Keitaro|Goto, Yasuyuki|Naito, Mariko|Wakai, Kenji|Tajima, Kazuo|Hamajima, Nobuyuki | ||||||||||
| PMID: | 19589142 | ||||||||||
| 12. | |||||||||||
| Journal: | BMC Gastroenterol. 2009 Oct 13;9:76. | ||||||||||
| Title: | Genetic factors associated with intestinal metaplasia in a high risk Singapore-Chinese population: a cohort study. | ||||||||||
| Author: | Zhu, Feng|Loh, Marie|Hill, Jeffrey|Lee, Sumarlin|Koh, King Xin|Lai, Kin Wai|Salto-Tellez, Manuel|Iacopetta, Barry|Yeoh, Khay Guan|Soong, Richie | ||||||||||
| PMID: | 19822020 | ||||||||||
| 13. | |||||||||||
| Journal: | Biochim Biophys Acta. 2009 Nov;1793(11):1623-33. | ||||||||||
| Title: | Cytokine signalling via gp130 in gastric cancer. | ||||||||||
| Author: | Howlett, M|Menheniott, T R|Judd, L M|Giraud, A S | ||||||||||
| PMID: | 19665497 | ||||||||||
| 14. | |||||||||||
| Journal: | J Biol Chem. 2010 May 21;285(21):16042-50. | ||||||||||
| Title: | Helicobacter pylori CagA phosphorylation status determines the gp130-activated SHP2/ERK and JAK/STAT signal transduction pathways in gastric epithelial cells. | ||||||||||
| Author: | Lee, In Ohk|Kim, Jie Hyun|Choi, Yeun Jung|Pillinger, Michael H|Kim, Seok-Yong|Blaser, Martin J|Lee, Yong Chan | ||||||||||
| PMID: | 20348091 | ||||||||||
| 15. | |||||||||||
| Journal: | World J Gastrointest Oncol. 2010 Oct 15;2(10):369-79. | ||||||||||
| Title: | Genetic predisposition to Helicobacter pylori-induced gastric precancerous conditions. | ||||||||||
| Author: | Hishida, Asahi|Matsuo, Keitaro|Goto, Yasuyuki|Hamajima, Nobuyuki | ||||||||||
| PMID: | 21160888 | ||||||||||
| 16. | |||||||||||
| Journal: | J Biol Chem. 2011 Sep 23;286(38):33622-31. | ||||||||||
| Title: | Potentiation of Helicobacter pylori CagA protein virulence through homodimerization. | ||||||||||
| Author: | Nagase, Lisa|Murata-Kamiya, Naoko|Hatakeyama, Masanori | ||||||||||
| PMID: | 21813645 | ||||||||||
| 17. | |||||||||||
| Journal: | J Int Med Res. 2012;40(6):2083-9. | ||||||||||
| Title: | Expression and clinical significance of SHP2 in gastric cancer. | ||||||||||
| Author: | Dong, S|Li, F-Q|Zhang, Q|Lv, K-Z|Yang, H-L|Gao, Y|Yu, J-R | ||||||||||
| PMID: | 23321164 | ||||||||||
| 18. | |||||||||||
| Journal: | Nihon Rinsho. 2012 Oct;70(10):1699-704. | ||||||||||
| Title: | [H. pylori oncoprotein CagA and gastric cancer]. | ||||||||||
| Author: | Hatakeyama, Masanori | ||||||||||
| PMID: | 23198548 | ||||||||||
| 19. | |||||||||||
| Journal: | BMC Gastroenterol. 2012 Jul 12;12:89. | ||||||||||
| Title: | Association of polymorphism of PTPN 11 encoding SHP-2 with gastric atrophy but not gastric cancer in Helicobacter pylori seropositive Chinese population. | ||||||||||
| Author: | Jiang, Jing|Jia, Zhi-Fang|Kong, Fei|Jin, Mei-Shan|Wang, Yin-Ping|Tian, Suyan|Suo, Jian|Cao, Xueyuan | ||||||||||
| PMID: | 22788847 | ||||||||||
| 20. | |||||||||||
| Journal: | Immunobiology. 2012 Sep;217(9):926-34. | ||||||||||
| Title: | Regulation of SHP2 by PTEN/AKT/GSK-3beta signaling facilitates IFN-gamma resistance in hyperproliferating gastric cancer. | ||||||||||
| Author: | Tseng, Po-Chun|Huang, Wei-Ching|Chen, Chia-Ling|Sheu, Bor-Shyang|Shan, Yan-Shen|Tsai, Cheng-Chieh|Wang, Chi-Yun|Chen, Su-O|Hsieh, Chia-Yuan|Lin, Chiou-Feng | ||||||||||
| PMID: | 22325465 | ||||||||||
| 21. | |||||||||||
| Journal: | PLoS One. 2012;7(2):e31020. | ||||||||||
| Title: | Genetic susceptibility on CagA-interacting molecules and gene-environment interaction with phytoestrogens: a putative risk factor for gastric cancer. | ||||||||||
| Author: | Yang, Jae Jeong|Cho, Lisa Y|Ko, Kwang-Pil|Shin, Aesun|Ma, Seung Hyun|Choi, Bo Youl|Han, Dong Soo|Song, Kyu Sang|Kim, Yong Sung|Lee, Jong-Young|Han, Bok Ghee|Chang, Soung-Hoon|Shin, Hai-Rim|Kang, Daehee|Yoo, Keun-Young|Park, Sue K | ||||||||||
| PMID: | 22383989 | ||||||||||
| 22. | |||||||||||
| Journal: | World J Gastroenterol. 2013 Jan 28;19(4):575-80. | ||||||||||
| Title: | Increased expression of tyrosine phosphatase SHP-2 in Helicobacter pylori-infected gastric cancer. | ||||||||||
| Author: | Jiang, Jing|Jin, Mei-Shan|Kong, Fei|Wang, Yin-Ping|Jia, Zhi-Fang|Cao, Dong-Hui|Ma, Hong-Xi|Suo, Jian|Cao, Xue-Yuan | ||||||||||
| PMID: | 23382639 | ||||||||||
| 23. | |||||||||||
| Journal: | Mutat Res Rev Mutat Res. 2014 Jan-Mar;759:14-26. | ||||||||||
| Title: | Host genetic factors respond to pathogenic step-specific virulence factors of Helicobacter pylori in gastric carcinogenesis. | ||||||||||
| Author: | He, Caiyun|Chen, Moye|Liu, Jingwei|Yuan, Yuan | ||||||||||
| PMID: | 24076409 | ||||||||||
| 24. | |||||||||||
| Journal: | Cancer Sci. 2014 Mar;105(3):245-51. | ||||||||||
| Title: | Natural variant of the Helicobacter pylori CagA oncoprotein that lost the ability to interact with PAR1. | ||||||||||
| Author: | Hashi, Kana|Murata-Kamiya, Naoko|Varon, Christine|Megraud, Francis|Dominguez-Bello, Maria Gloria|Hatakeyama, Masanori | ||||||||||
| PMID: | 24354359 | ||||||||||
| 25. | |||||||||||
| Journal: | Biomed Pharmacother. 2014 Apr;68(3):285-90. | ||||||||||
| Title: | Expression and clinical significance of tyrosine phosphatase SHP-2 in colon cancer. | ||||||||||
| Author: | Cai, Peifen|Guo, Wenjie|Yuan, Huaqin|Li, Qian|Wang, Weicheng|Sun, Yang|Li, Xiaomin|Gu, Yanhong | ||||||||||
| PMID: | 24439672 | ||||||||||
| 26. | |||||||||||
| Journal: | Oncotarget. 2015 Aug 7;6(22):19017-26. | ||||||||||
| Title: | SNP interactions of Helicobacter pylori-related host genes PGC, PTPN11, IL1B, and TLR4 in susceptibility to gastric carcinogenesis. | ||||||||||
| Author: | He, Caiyun|Tu, Huakang|Sun, Liping|Xu, Qian|Gong, Yuehua|Jing, Jingjing|Dong, Nannan|Yuan, Yuan | ||||||||||
| PMID: | 26158864 | ||||||||||
| 27. | |||||||||||
| Journal: | Sci Rep. 2015 Oct 28;5:15749. | ||||||||||
| Title: | Dramatic increase in SHP2 binding activity of Helicobacter pylori Western CagA by EPIYA-C duplication: its implications in gastric carcinogenesis. | ||||||||||
| Author: | Nagase, Lisa|Hayashi, Takeru|Senda, Toshiya|Hatakeyama, Masanori | ||||||||||
| PMID: | 26507409 | ||||||||||
| 28. | |||||||||||
| Journal: | J Cell Mol Med. 2015 Sep;19(9):2075-83. | ||||||||||
| Title: | Functions of Shp2 in cancer. | ||||||||||
| Author: | Zhang, Jie|Zhang, Fei|Niu, Ruifang | ||||||||||
| PMID: | 26088100 | ||||||||||
| 29. | |||||||||||
| Journal: | Gastric Cancer. 2015 Jan;18(1):65-76. | ||||||||||
| Title: | Integrated analysis of cancer-related pathways affected by genetic and epigenetic alterations in gastric cancer. | ||||||||||
| Author: | Yoda, Yukie|Takeshima, Hideyuki|Niwa, Tohru|Kim, Jeong Goo|Ando, Takayuki|Kushima, Ryoji|Sugiyama, Toshiro|Katai, Hitoshi|Noshiro, Hirokazu|Ushijima, Toshikazu | ||||||||||
| PMID: | 24510342 | ||||||||||
| 30. | |||||||||||
| Journal: | Asian Pac J Cancer Prev. 2016;17(3):979-84. | ||||||||||
| Title: | Rare Helicobacter pylori Infection May Explain Low Stomach Cancer Incidence: Ecological Observations in Bali, Indonesia. | ||||||||||
| Author: | Tanaka, Tsutomu|Mulyadi, I Ketut|Moestikaningsih|Oka, Tjok Gede|Soeripto|Triningsih, Fx Ediati|Triyono, Teguh|Heriyanto, Didik Setyo|Hosono, Akihiro|Suzuki, Sadao|Tokudome, Shinkan | ||||||||||
| PMID: | 27039823 | ||||||||||
| 31. | |||||||||||
| Journal: | Nat Microbiol. 2016 Mar 14;1:16026. | ||||||||||
| Title: | Host SHP1 phosphatase antagonizes Helicobacter pylori CagA and can be downregulated by Epstein-Barr virus. | ||||||||||
| Author: | Saju, Priya|Murata-Kamiya, Naoko|Hayashi, Takeru|Senda, Yoshie|Nagase, Lisa|Noda, Saori|Matsusaka, Keisuke|Funata, Sayaka|Kunita, Akiko|Urabe, Masayuki|Seto, Yasuyuki|Fukayama, Masashi|Kaneda, Atsushi|Hatakeyama, Masanori | ||||||||||
| PMID: | 27572445 | ||||||||||
| 32. | |||||||||||
| Journal: | Cell Physiol Biochem. 2016;39(4):1537-52. | ||||||||||
| Title: | Chemotherapy Effectiveness and Prognosis of Gastric Cancer Influenced by PTPN11 Polymorphisms. | ||||||||||
| Author: | Zhuo, Chuanjun|Shao, Mingjing|Chen, Ce|Lin, Chongguang|Jiang, Deguo|Chen, Guangdong|Tian, Hongjun|Wang, Lina|Li, Jie|Lin, Xiaodong | ||||||||||
| PMID: | 27614952 | ||||||||||
| 33. | |||||||||||
| Journal: | Cell Rep. 2017 Sep 19;20(12):2876-2890. | ||||||||||
| Title: | Differential Mechanisms for SHP2 Binding and Activation Are Exploited by Geographically Distinct Helicobacter pylori CagA Oncoproteins. | ||||||||||
| Author: | Hayashi, Takeru|Senda, Miki|Suzuki, Nobuhiro|Nishikawa, Hiroko|Ben, Chi|Tang, Chao|Nagase, Lisa|Inoue, Kaori|Senda, Toshiya|Hatakeyama, Masanori | ||||||||||
| PMID: | 28930683 | ||||||||||
| 34. | |||||||||||
| Journal: | Nat Med. 2018 Jul;24(7):968-977. | ||||||||||
| Title: | Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition. | ||||||||||
| Author: | Wong, Gabrielle S|Zhou, Jin|Liu, Jie Bin|Wu, Zhong|Xu, Xinsen|Li, Tianxia|Xu, David|Schumacher, Steven E|Puschhof, Jens|McFarland, James|Zou, Charles|Dulak, Austin|Henderson, Les|Xu, Peng|O'Day, Emily|Rendak, Rachel|Liao, Wei-Li|Cecchi, Fabiola|Hembrough, | ||||||||||
| PMID: | 29808010 | ||||||||||
| 35. | |||||||||||
| Journal: | Comput Biol Chem. 2018 Oct;76:17-22. | ||||||||||
| Title: | Intramolecular energies of the cytotoxic protein CagA of Helicobacter pylori as a possible descriptor of strains' pathogenicity level. | ||||||||||
| Author: | Rojas-Rengifo, Diana F|Alvarez-Silva, Maria Camila|Ulloa-Guerrero, Cindy P|Nunez-Velez, Vanessa Lucia|Del Pilar Delgado, Maria|Aguilera, Sonia Milena|Castro, Harold|Jaramillo, Carlos Alberto|Fernando Gonzalez Barrios, Andres | ||||||||||
| PMID: | 29864542 | ||||||||||
| 36. | |||||||||||
| Journal: | Sci Rep. 2018 Oct 29;8(1):15981. | ||||||||||
| Title: | Evaluating the origin and virulence of a Helicobacter pylori cagA-positive strain isolated from a non-human primate. | ||||||||||
| Author: | Hashi, Kana|Imai, Chihiro|Yahara, Koji|Tahmina, Kamrunnesa|Hayashi, Takeru|Azuma, Takeshi|Miyabe-Nishiwaki, Takako|Sato, Hideyuki|Matsuoka, Masao|Niimi, Sachi|Okamoto, Munehiro|Hatakeyama, Masanori | ||||||||||
| PMID: | 30374120 | ||||||||||