Primary Site >> Colorectal Cancer
Gene >> PTPN11
| 1. | |||||||||||
| Journal: | Oncogene. 1995 Nov 16;11(10):1955-62. | ||||||||||
| Title: | Regulation of the Src tyrosine kinase and Syp tyrosine phosphatase by their cellular association. | ||||||||||
| Author: | Peng, Z Y|Cartwright, C A | ||||||||||
| PMID: | 7478513 | ||||||||||
| 2. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2004 Jul 30;320(3):875-9. | ||||||||||
| Title: | NSAIDs activate PTEN and other phosphatases in human colon cancer cells: novel mechanism for chemopreventive action of NSAIDs. | ||||||||||
| Author: | Chu, Eric C|Chai, Jianyuan|Tarnawski, Andrzej S | ||||||||||
| PMID: | 15240129 | ||||||||||
| 3. | |||||||||||
| Journal: | Am J Physiol Gastrointest Liver Physiol. 2006 Dec;291(6):G1100-12. Epub 2006 Aug | ||||||||||
| Title: | Deoxycholic acid differentially regulates focal adhesion kinase phosphorylation: role of tyrosine phosphatase ShP2. | ||||||||||
| Author: | Khare, Sharad|Holgren, Cory|Samarel, Allen M | ||||||||||
| PMID: | 16920701 | ||||||||||
| 4. | |||||||||||
| Journal: | Genes Chromosomes Cancer. 2008 Mar;47(3):253-9. | ||||||||||
| Title: | SOS1 mutations are rare in human malignancies: implications for Noonan Syndrome patients. | ||||||||||
| Author: | Swanson, Kenneth D|Winter, Jordan M|Reis, Marcelo|Bentires-Alj, Mohamed|Greulich, Heidi|Grewal, Rupinder|Hruban, Ralph H|Yeo, Charles J|Yassin, Yosuf|Iartchouk, Oleg|Montgomery, Kate|Whitman, Susan P|Caligiuri, Michael A|Loh, Mignon L|Gilliland, D Gary|Lo | ||||||||||
| PMID: | 18064648 | ||||||||||
| 5. | |||||||||||
| Journal: | Neurosignals. 2008;16(2-3):235-45. | ||||||||||
| Title: | Tyrosine phosphorylation of netrin receptors in netrin-1 signaling. | ||||||||||
| Author: | Ren, Xiu-Rong|Hong, Yan|Feng, Zhu|Yang, Hong-Mei|Mei, Lin|Xiong, Wen-Cheng | ||||||||||
| PMID: | 18253061 | ||||||||||
| 6. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2592-7. | ||||||||||
| Title: | Identification and functional characterization of paxillin as a target of protein tyrosine phosphatase receptor T. | ||||||||||
| Author: | Zhao, Yiqing|Zhang, Xiaodong|Guda, Kishore|Lawrence, Earl|Sun, Qun|Watanabe, Toshio|Iwakura, Yoichiro|Asano, Masahide|Wei, Lanlan|Yang, Zhirong|Zheng, Weiping|Dawson, Dawn|Willis, Joseph|Markowitz, Sanford D|Satake, Masanobu|Wang, Zhenghe | ||||||||||
| PMID: | 20133777 | ||||||||||
| 7. | |||||||||||
| Journal: | J Mol Cell Biol. 2010 Aug;2(4):223-30. | ||||||||||
| Title: | Association of Shp2 with phosphorylated IL-22R1 is required for interleukin-22-induced MAP kinase activation. | ||||||||||
| Author: | Meng, Songshu|Gui, Qiu|Xu, Qing|Lu, Kaixin|Jiao, Xinan|Fan, Jian|Ge, Baoxue|Ke, Yuehai|Zhang, Shengping|Wu, Jie|Wang, Chuangui | ||||||||||
| PMID: | 20671117 | ||||||||||
| 8. | |||||||||||
| Journal: | World J Gastroenterol. 2011 Apr 21;17(15):2028-36. | ||||||||||
| Title: | SPARCL1, Shp2, MSH2, E-cadherin, p53, ADCY-2 and MAPK are prognosis-related in colorectal cancer. | ||||||||||
| Author: | Yu, Shu-Jing|Yu, Jie-Kai|Ge, Wei-Ting|Hu, Han-Guang|Yuan, Ying|Zheng, Shu | ||||||||||
| PMID: | 21528083 | ||||||||||
| 9. | |||||||||||
| Journal: | Gut. 2014 Sep;63(9):1457-67. | ||||||||||
| Title: | Gene expression profiling-derived immunohistochemistry signature with high prognostic value in colorectal carcinoma. | ||||||||||
| Author: | Chang, Wenjun|Gao, Xianhua|Han, Yifang|Du, Yan|Liu, Qizhi|Wang, Lei|Tan, Xiaojie|Zhang, Qi|Liu, Yan|Zhu, Yan|Yu, Yongwei|Fan, Xinjuan|Zhang, Hongwei|Zhou, Weiping|Wang, Jianping|Fu, Chuangang|Cao, Guangwen | ||||||||||
| PMID: | 24173294 | ||||||||||
| 10. | |||||||||||
| Journal: | Biomed Pharmacother. 2014 Apr;68(3):285-90. | ||||||||||
| Title: | Expression and clinical significance of tyrosine phosphatase SHP-2 in colon cancer. | ||||||||||
| Author: | Cai, Peifen|Guo, Wenjie|Yuan, Huaqin|Li, Qian|Wang, Weicheng|Sun, Yang|Li, Xiaomin|Gu, Yanhong | ||||||||||
| PMID: | 24439672 | ||||||||||
| 11. | |||||||||||
| Journal: | Mol Cancer Ther. 2014 May;13(5):1206-16. | ||||||||||
| Title: | Embelin reduces colitis-associated tumorigenesis through limiting IL-6/STAT3 signaling. | ||||||||||
| Author: | Dai, Yun|Jiao, Hongmei|Teng, Guigen|Wang, Weihong|Zhang, Rongxin|Wang, Yunhong|Hebbard, Lionel|George, Jacob|Qiao, Liang | ||||||||||
| PMID: | 24651526 | ||||||||||
| 12. | |||||||||||
| Journal: | Am J Cancer Res. 2015 May 15;5(6):1972-87. eCollection 2015. | ||||||||||
| Title: | YES oncogenic activity is specified by its SH4 domain and regulates RAS/MAPK signaling in colon carcinoma cells. | ||||||||||
| Author: | Dubois, Fanny|Leroy, Cedric|Simon, Valerie|Benistant, Christine|Roche, Serge | ||||||||||
| PMID: | 26269757 | ||||||||||
| 13. | |||||||||||
| Journal: | Cell Rep. 2015 Sep 29;12(12):1978-85. | ||||||||||
| Title: | PTPN11 Is a Central Node in Intrinsic and Acquired Resistance to Targeted Cancer Drugs. | ||||||||||
| Author: | Prahallad, Anirudh|Heynen, Guus J J E|Germano, Giovanni|Willems, Stefan M|Evers, Bastiaan|Vecchione, Loredana|Gambino, Valentina|Lieftink, Cor|Beijersbergen, Roderick L|Di Nicolantonio, Federica|Bardelli, Alberto|Bernards, Rene | ||||||||||
| PMID: | 26365186 | ||||||||||
| 14. | |||||||||||
| Journal: | Oncotarget. 2016 Oct 4;7(40):65676-65695. | ||||||||||
| Title: | SHP-2 phosphatase contributes to KRAS-driven intestinal oncogenesis but prevents colitis-associated cancer development. | ||||||||||
| Author: | Gagne-Sansfacon, Jessica|Coulombe, Genevieve|Langlois, Marie-Josee|Langlois, Ariane|Paquet, Marilene|Carrier, Julie|Feng, Gen-Sheng|Qu, Cheng-Kui|Rivard, Nathalie | ||||||||||
| PMID: | 27582544 | ||||||||||
| 15. | |||||||||||
| Journal: | Oncotarget. 2017 Jan 31;8(5):7586-7597. | ||||||||||
| Title: | T lymphocyte SHP2-deficiency triggers anti-tumor immunity to inhibit colitis-associated cancer in mice. | ||||||||||
| Author: | Liu, Wen|Guo, Wenjie|Shen, Lihong|Chen, Zhen|Luo, Qiong|Luo, Xiaolin|Feng, GenSheng|Shu, Yongqian|Gu, Yanhong|Xu, Qiang|Sun, Yang | ||||||||||
| PMID: | 27935860 | ||||||||||
| 16. | |||||||||||
| Journal: | Genes Chromosomes Cancer. 2017 Nov;56(11):769-787. | ||||||||||
| Title: | The co-regulatory networks of tumor suppressor genes, oncogenes, and miRNAs in colorectal cancer. | ||||||||||
| Author: | Slattery, Martha L|Herrick, Jennifer S|Mullany, Lila E|Samowitz, Wade S|Sevens, John R|Sakoda, Lori|Wolff, Roger K | ||||||||||
| PMID: | 28675510 | ||||||||||
| 17. | |||||||||||
| Journal: | Ann Surg. 2017 Oct;266(4):610-616. | ||||||||||
| Title: | Understanding and Resetting Radiation Sensitivity in Rectal Cancer. | ||||||||||
| Author: | Kelley, Katherine A|Ruhl, Rebecca A|Rana, Shushan R|Dewey, Elizabeth|Espinosa, Cristina|Thomas, Charles R Jr|Martindale, Robert G|Anand, Sudarshan|Tsikitis, Vassiliki L | ||||||||||
| PMID: | 28742699 | ||||||||||
| 18. | |||||||||||
| Journal: | J Gastrointest Cancer. 2017 Nov 7. pii: 10.1007/s12029-017-0024-9. | ||||||||||
| Title: | A Deregulated PI3K-AKT Signaling Pathway in Patients with Colorectal Cancer. | ||||||||||
| Author: | Zhang, Tao|Ma, Yuanping|Fang, Jiansong|Liu, Chang|Chen, Liangrong | ||||||||||
| PMID: | 29110225 | ||||||||||
| 19. | |||||||||||
| Journal: | Sci Rep. 2017 Dec 14;7(1):17597. | ||||||||||
| Title: | SHP2 associates with nuclear localization of STAT3: significance in progression and prognosis of colorectal cancer. | ||||||||||
| Author: | Huang, Yan|Wang, Jie|Cao, Fuao|Jiang, Hailong|Li, An|Li, Jianzhong|Qiu, Lei|Shen, Hao|Chang, Wenjun|Zhou, Chuanxiang|Pan, Yamin|Lu, Yiming | ||||||||||
| PMID: | 29242509 | ||||||||||
| 20. | |||||||||||
| Journal: | Mol Carcinog. 2018 May;57(5):619-628. | ||||||||||
| Title: | The gain-of-function mutation E76K in SHP2 promotes CAC tumorigenesis and induces EMT via the Wnt/beta-catenin signaling pathway. | ||||||||||
| Author: | Zhang, Qian|Li, Yao|Zhao, Rongrong|Wang, Xinyi|Fan, Chuling|Xu, Youzhi|Liu, Yakun|Li, Jiabin|Wang, Siying | ||||||||||
| PMID: | 29323748 | ||||||||||
| 21. | |||||||||||
| Journal: | Oncogene. 2018 Mar;37(12):1576-1593. | ||||||||||
| Title: | BRAF inhibition upregulates a variety of receptor tyrosine kinases and their downstream effector Gab2 in colorectal cancer cell lines. | ||||||||||
| Author: | Herr, Ricarda|Halbach, Sebastian|Heizmann, Miriam|Busch, Hauke|Boerries, Melanie|Brummer, Tilman | ||||||||||
| PMID: | 29326440 | ||||||||||
| 22. | |||||||||||
| Journal: | Anticancer Res. 2018 Apr;38(4):2235-2240. | ||||||||||
| Title: | Racial Disparities in the Molecular Landscape of Cancer. | ||||||||||
| Author: | Heath, Elisabeth I|Lynce, Filipa|Xiu, Joanne|Ellerbrock, Angela|Reddy, Sandeep K|Obeid, Elias|Liu, Stephen V|Bollig-Fischer, Aliccia|Separovic, Duska|Vanderwalde, Ari | ||||||||||
| PMID: | 29599344 | ||||||||||
| 23. | |||||||||||
| Journal: | Int J Mol Med. 2018 Jul;42(1):368-380. | ||||||||||
| Title: | Inflammatory genes are novel prognostic biomarkers for colorectal cancer. | ||||||||||
| Author: | Jiang, Hao|Dong, Li|Gong, Fangyan|Gu, Yuping|Zhang, Henghun|Fan, Dong|Sun, Zhiguo | ||||||||||
| PMID: | 29693170 | ||||||||||
| 24. | |||||||||||
| Journal: | Nat Med. 2018 Jul;24(7):961-967. | ||||||||||
| Title: | SHP2 is required for growth of KRAS-mutant non-small-cell lung cancer in vivo. | ||||||||||
| Author: | Mainardi, Sara|Mulero-Sanchez, Antonio|Prahallad, Anirudh|Germano, Giovanni|Bosma, Astrid|Krimpenfort, Paul|Lieftink, Cor|Steinberg, Jeffrey D|de Wit, Niels|Goncalves-Ribeiro, Samuel|Nadal, Ernest|Bardelli, Alberto|Villanueva, Alberto|Bernards, Rene | ||||||||||
| PMID: | 29808006 | ||||||||||
| 25. | |||||||||||
| Journal: | Int J Cancer. 2018 Jul 10. | ||||||||||
| Title: | Clinical significance and biological function of WD repeat domain 54 as an oncogene in colorectal cancer. | ||||||||||
| Author: | Yuan, Yuncang|Qi, Guoxiang|Shen, Hao|Guo, Aizhen|Cao, Fuao|Zhu, Yan|Xiao, Chunjie|Chang, Wenjun|Zheng, Shangyong | ||||||||||
| PMID: | 29987896 | ||||||||||
| 26. | |||||||||||
| Journal: | Cancer Cell. 2018 Aug 13;34(2):298-314.e7. | ||||||||||
| Title: | Therapeutic Ablation of Gain-of-Function Mutant p53 in Colorectal Cancer Inhibits Stat3-Mediated Tumor Growth and Invasion. | ||||||||||
| Author: | Schulz-Heddergott, Ramona|Stark, Nadine|Edmunds, Shelley J|Li, Jinyu|Conradi, Lena-Christin|Bohnenberger, Hanibal|Ceteci, Fatih|Greten, Florian R|Dobbelstein, Matthias|Moll, Ute M | ||||||||||
| PMID: | 30107178 | ||||||||||