Primary Site >> Colorectal Cancer

Gene >> PTPN1

Journal: J Biol Chem. 2005 Mar 4;280(9):8180-7. Epub 2004 Dec 20.
Title: Crystal structure of the PTPL1/FAP-1 human tyrosine phosphatase mutated in colorectal cancer: evidence for a second phosphotyrosine substrate recognition pocket.
Author: Villa, Fabrizio|Deak, Maria|Bloomberg, Graham B|Alessi, Dario R|van Aalten, Daan M F
PMID: 15611135
Journal: J Mol Med (Berl). 2007 Mar;85(3):293-304. Epub 2006 Dec 2.
Title: Array CGH identifies distinct DNA copy number profiles of oncogenes and tumor suppressor genes in chromosomal- and microsatellite-unstable sporadic colorectal carcinomas.
Author: Lassmann, Silke|Weis, Roland|Makowiec, Frank|Roth, Jasmine|Danciu, Mihai|Hopt, Ulrich|Werner, Martin
PMID: 17143621
Journal: Cancer Res. 2007 Nov 1;67(21):10129-37.
Title: PTP1B contributes to the oncogenic properties of colon cancer cells through Src activation.
Author: Zhu, Shudong|Bjorge, Jeffrey D|Fujita, Donald J
PMID: 17974954
Journal: Int J Cancer. 2008 May 1;122(9):1999-2007.
Title: Apoptosis of estrogen-receptor negative breast cancer and colon cancer cell lines by PTP alpha and src RNAi.
Author: Zheng, Xinmin|Resnick, Ross J|Shalloway, David
PMID: 18183590
Journal: Mar Drugs. 2009;7(1):24-44.
Title: Actinomycetes for marine drug discovery isolated from mangrove soils and plants in China.
Author: Hong, Kui|Gao, An-Hui|Xie, Qing-Yi|Gao, Hao|Zhuang, Ling|Lin, Hai-Peng|Yu, Hai-Ping|Li, Jia|Yao, Xin-Sheng|Goodfellow, Michael|Ruan, Ji-Sheng
PMID: 19370169
Journal: Mar Drugs. 2012 May;10(5):1027-36.
Title: Woodylides A-C, new cytotoxic linear polyketides from the South China Sea sponge Plakortis simplex.
Author: Yu, Hao-Bing|Liu, Xiang-Fang|Xu, Ying|Gan, Jian-Hong|Jiao, Wei-Hua|Shen, Yang|Lin, Hou-Wen
PMID: 22822354
Journal: Int J Cancer. 2013 Jul;133(1):67-78.
Title: MiRNA-362-3p induces cell cycle arrest through targeting of E2F1, USF2 and PTPN1 and is associated with recurrence of colorectal cancer.
Author: Christensen, Lise Lotte|Tobiasen, Heidi|Holm, Anja|Schepeler, Troels|Ostenfeld, Marie S|Thorsen, Kasper|Rasmussen, Mads H|Birkenkamp-Demtroeder, Karin|Sieber, Oliver M|Gibbs, Peter|Lubinski, Jan|Lamy, Philippe|Laurberg, Soren|Oster, Bodil|Hansen, Kristian
PMID: 23280316
Journal: J Clin Invest. 2013 Aug;123(8):3459-71.
Title: Metastasis-associated PRL-3 induces EGFR activation and addiction in cancer cells.
Author: Al-Aidaroos, Abdul Qader Omer|Yuen, Hiu Fung|Guo, Ke|Zhang, Shu Dong|Chung, Tae-Hoon|Chng, Wee Joo|Zeng, Qi
PMID: 23867504
Journal: J Mol Histol. 2014 Apr;45(2):153-9.
Title: Overexpression of PTP1B in human colorectal cancer and its association with tumor progression and prognosis.
Author: Chen, Queting|Li, Yong|Li, Zhong|Zhao, Qun|Fan, Liqiao
PMID: 23990346
Journal: PLoS One. 2014 Jan 22;9(1):e85796.
Title: pTyr421 cortactin is overexpressed in colon cancer and is dephosphorylated by curcumin: involvement of non-receptor type 1 protein tyrosine phosphatase (PTPN1).
Author: Radhakrishnan, Vijayababu M|Kojs, Pawel|Young, Gavin|Ramalingam, Rajalakshmy|Jagadish, Bhumasamudram|Mash, Eugene A|Martinez, Jesse D|Ghishan, Fayez K|Kiela, Pawel R
PMID: 24465712
Journal: Cancer Lett. 2015 Apr 10;359(2):218-25.
Title: PTP1B promotes cell proliferation and metastasis through activating src and ERK1/2 in non-small cell lung cancer.
Author: Liu, Hongbing|Wu, Ying|Zhu, Suhua|Liang, Wenjun|Wang, Zhaofeng|Wang, Yunfen|Lv, Tangfeng|Yao, Yanwen|Yuan, Dongmei|Song, Yong
PMID: 25617799
Journal: Oncotarget. 2016 Apr 19;7(16):21922-38.
Title: Increased PTP1B expression and phosphatase activity in colorectal cancer results in a more invasive phenotype and worse patient outcome.
Author: Hoekstra, Elmer|Das, Asha M|Swets, Marloes|Cao, Wanlu|van der Woude, C Janneke|Bruno, Marco J|Peppelenbosch, Maikel P|Kuppen, Peter J K|Ten Hagen, Timo L M|Fuhler, Gwenny M
PMID: 26942883
Journal: Sci Rep. 2016 Oct 18;6:35308.
Title: Protein tyrosine phosphatase 1B targets PITX1/p120RasGAP thus showing therapeutic potential in colorectal carcinoma.
Author: Teng, Hao-Wei|Hung, Man-Hsin|Chen, Li-Ju|Chang, Mao-Ju|Hsieh, Feng-Shu|Tsai, Ming-Hsien|Huang, Jui-Wen|Lin, Chih-Lung|Tseng, Hsiang-Wen|Kuo, Zong-Keng|Jiang, Jeng-Kai|Yang, Shung-Haur|Shiau, Chung-Wai|Chen, Kuen-Feng
PMID: 27752061
Journal: PLoS One. 2016 Nov 17;11(11):e0166538.
Title: Cell Transformation by PTP1B Truncated Mutants Found in Human Colon and Thyroid Tumors.
Author: Mei, Wenhan|Wang, Kemin|Huang, Jian|Zheng, Xinmin
PMID: 27855221