Primary Site >> Colorectal Cancer

Gene >> PTK6

Journal: Clin Cancer Res. 1999 Jul;5(7):1767-77.
Title: BRK/Sik expression in the gastrointestinal tract and in colon tumors.
Author: Llor, X|Serfas, M S|Bie, W|Vasioukhin, V|Polonskaia, M|Derry, J|Abbott, C M|Tyner, A L
PMID: 10430081
Journal: Int J Cancer. 1999 Nov 26;83(5):579-84.
Title: Comparative tyrosine-kinase profiles in colorectal cancers: enhanced arg expression in carcinoma as compared with adenoma and normal mucosa.
Author: Chen, W S|Kung, H J|Yang, W K|Lin, W c
PMID: 10521789
Journal: Biochim Biophys Acta. 2010 Aug;1806(1):66-73.
Title: Building a better understanding of the intracellular tyrosine kinase PTK6 - BRK by BRK.
Author: Brauer, Patrick M|Tyner, Angela L
PMID: 20193745
Journal: Tumour Biol. 2011 Oct;32(5):873-80.
Title: Detection of Brk expression in non-small cell lung cancer: clinicopathological relevance.
Author: Fan, Chuifeng|Zhao, Yang|Liu, Di|Zhang, Xiupeng|Wang, Enhua
PMID: 21603980
Journal: Gastroenterology. 2011 Oct;141(4):1371-80, 1380.e1-2.
Title: Disruption of the mouse protein tyrosine kinase 6 gene prevents STAT3 activation and confers resistance to azoxymethane.
Author: Gierut, Jessica|Zheng, Yu|Bie, Wenjun|Carroll, Robert E|Ball-Kell, Susan|Haegebarth, Andrea|Tyner, Angela L
PMID: 21741923
Journal: PLoS One. 2012;7(7):e42001.
Title: A comprehensive characterization of genome-wide copy number aberrations in colorectal cancer reveals novel oncogenes and patterns of alterations.
Author: Xie, Tao|D' Ario, Giovanni|Lamb, John R|Martin, Eric|Wang, Kai|Tejpar, Sabine|Delorenzi, Mauro|Bosman, Fred T|Roth, Arnaud D|Yan, Pu|Bougel, Stephanie|Di Narzo, Antonio Fabio|Popovici, Vlad|Budinska, Eva|Mao, Mao|Weinrich, Scott L|Rejto, Paul A|Hodgson, J
PMID: 22860045
Journal: Mol Cancer Ther. 2012 Nov;11(11):2311-20.
Title: Targeting protein tyrosine kinase 6 enhances apoptosis of colon cancer cells following DNA damage.
Author: Gierut, Jessica J|Mathur, Priya S|Bie, Wenjun|Han, Jin|Tyner, Angela L
PMID: 22989419
Journal: Oncogene. 2013 Sep 5;32(36):4304-12.
Title: Protein tyrosine kinase 6 protects cells from anoikis by directly phosphorylating focal adhesion kinase and activating AKT.
Author: Zheng, Y|Gierut, J|Wang, Z|Miao, J|Asara, J M|Tyner, A L
PMID: 23027128
Journal: Cancer Lett. 2016 Apr 10;373(2):203-13.
Title: MicroRNA-187, a downstream effector of TGFbeta pathway, suppresses Smad-mediated epithelial-mesenchymal transition in colorectal cancer.
Author: Zhang, Feifei|Luo, Yuhao|Shao, Ziyun|Xu, Lijun|Liu, Xiaoxu|Niu, Ya|Shi, Jiaolong|Sun, Xuegang|Liu, Yawei|Ding, Yanqing|Zhao, Liang
PMID: 26820227
Journal: Mol Cancer Res. 2016 Jun;14(6):563-73.
Title: Kinase-Dependent and -Independent Roles for PTK6 in Colon Cancer.
Author: Mathur, Priya S|Gierut, Jessica J|Guzman, Grace|Xie, Hui|Xicola, Rosa M|Llor, Xavier|Chastkofsky, Michael I|Perekatt, Ansu O|Tyner, Angela L
PMID: 26983689
Journal: Mol Carcinog. 2017 Mar;56(3):1030-1040.
Title: Murine MTHFD1-synthetase deficiency, a model for the human MTHFD1 R653Q polymorphism, decreases growth of colorectal tumors.
Author: Levesque, Nancy|Christensen, Karen E|Van Der Kraak, Lauren|Best, Ana F|Deng, Liyuan|Caldwell, Don|MacFarlane, Amanda J|Beauchemin, Nicole|Rozen, Rima
PMID: 27597531