Primary Site >> Colorectal Cancer
Gene >> PTK6
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Ref: BRK/Sik expression in the gastrointestinal tract and in colon tumors. PMID: 10430081 Ref: Comparative tyrosine-kinase profiles in colorectal cancers: enhanced arg expression in carcinoma as compared with adenoma and normal mucosa. PMID: 10521789 |
Ref: Building a better understanding of the intracellular tyrosine kinase PTK6 - BRK by BRK. PMID: 20193745 |
Ref: Detection of Brk expression in non-small cell lung cancer: clinicopathological relevance. PMID: 21603980 Ref: Disruption of the mouse protein tyrosine kinase 6 gene prevents STAT3 activation and confers resistance to azoxymethane. PMID: 21741923 |
Ref: A comprehensive characterization of genome-wide copy number aberrations in colorectal cancer reveals novel oncogenes and patterns of alterations. PMID: 22860045 Ref: Targeting protein tyrosine kinase 6 enhances apoptosis of colon cancer cells following DNA damage. PMID: 22989419 |
Ref: Protein tyrosine kinase 6 protects cells from anoikis by directly phosphorylating focal adhesion kinase and activating AKT. PMID: 23027128 |
Ref: MicroRNA-187, a downstream effector of TGFbeta pathway, suppresses Smad-mediated epithelial-mesenchymal transition in colorectal cancer. PMID: 26820227 Ref: Kinase-Dependent and -Independent Roles for PTK6 in Colon Cancer. PMID: 26983689 |
Ref: Murine MTHFD1-synthetase deficiency, a model for the human MTHFD1 R653Q polymorphism, decreases growth of colorectal tumors. PMID: 27597531 |