Primary Site >> Liver Cancer

Gene >> PTK2

Journal: Cell Growth Differ. 1996 Nov;7(11):1513-23.
Title: Hepatocyte growth factor/scatter factor overexpression induces growth, abnormal development, and tumor formation in transgenic mouse livers.
Author: Sakata, H|Takayama, H|Sharp, R|Rubin, J S|Merlino, G|LaRochelle, W J
PMID: 8930401
Journal: Ann Surg Oncol. 1997 Apr-May;4(3):264-8.
Title: Overexpression of focal adhesion kinase (p125FAK) in human colorectal carcinoma liver metastases: independence from c-src or c-yes activation.
Author: Han, N M|Fleming, R Y|Curley, S A|Gallick, G E
PMID: 9142389
Journal: Shi Yan Sheng Wu Xue Bao. 2000 Dec;33(4):333-9.
Title: [TGF-beta 1 rapidly reduced hepatocarcinoma cells adhesion on to fibronectin and stimulated FAK dephosphorylation].
Author: Cai, T|Lei, Q Y|Zha, X L
PMID: 12549072
Journal: Cancer Lett. 2001 Jun 26;167(2):193-204.
Title: Proteolysis of integrin alpha5 and beta1 subunits involved in retinoic acid-induced apoptosis in human hepatoma Hep3B cells.
Author: Hsu, S L|Cheng, C C|Shi, Y R|Chiang, C W
PMID: 11369141
Journal: Zhonghua Zhong Liu Za Zhi. 2001 Mar;23(2):125-7.
Title: [Influence of focal adhesion kinase (FAK) on the biological behaviors of human hepatocellular carcinoma cells].
Author: Fang, Y|Fang, X|Wang, L
PMID: 11783016
Journal: Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai). 2001;33(1):53-58.
Title: Role of FAK in TNF-alpha/Cycloheximide-induced Apoptosis of SMMC-7721 Cells.
Author: Fang, Yi|Jin, Jia-Wei|Zha, Xi-Liang
PMID: 12053189
Journal: World J Gastroenterol. 2002 Aug;8(4):613-8.
Title: Expression of focal adhesion kinase and alpha5 and beta1 integrins in carcinomas and its clinical significance.
Author: Su, Jian-Min|Gui, Lu|Zhou, Yi-Ping|Zha, Xi-Liang
PMID: 12174366
Journal: Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai). 2003 Feb;35(2):161-6.
Title: [The effects of PTEN gene on migration and FAK phosphorylation of SMMC-7721 human hepatocarcinoma cell line].
Author: Zhang, Li-Neng|Yu, Qiang|Wang, Li-Ying|Jin, Jia-Wei|Zha, Xi-Liang
PMID: 12545224
Journal: Hepatology. 2003 Nov;38(5):1242-9.
Title: PTK2 and EIF3S3 genes may be amplification targets at 8q23-q24 and are associated with large hepatocellular carcinomas.
Author: Okamoto, Hiroyuki|Yasui, Kohichiroh|Zhao, Chen|Arii, Shigeki|Inazawa, Johji
PMID: 14578863
Journal: Clin Cancer Res. 2004 Apr 15;10(8):2812-7.
Title: Role of expression of focal adhesion kinase in progression of hepatocellular carcinoma.
Author: Itoh, Shinji|Maeda, Takashi|Shimada, Mitsuo|Aishima, Shin-ichi|Shirabe, Ken|Tanaka, Shinji|Maehara, Yoshihiko
PMID: 15102689
Journal: Mod Pathol. 2004 Jun;17(6):617-22.
Title: Analysis of DNA copy number aberrations in hepatitis C virus-associated hepatocellular carcinomas by conventional CGH and array CGH.
Author: Hashimoto, Kiichiro|Mori, Naohide|Tamesa, Takao|Okada, Toshimasa|Kawauchi, Shigeto|Oga, Atsunori|Furuya, Tomoko|Tangoku, Akira|Oka, Masaaki|Sasaki, Kohsuke
PMID: 15133472
Journal: Oncogene. 2004 Aug 19;23(37):6272-81.
Title: Involvement of c-Src kinase in the regulation of TGF-beta1-induced apoptosis.
Author: Park, Seok Soon|Eom, Young-Woo|Kim, Eun Hee|Lee, Ji Hyun|Min, Do Sik|Kim, Sungsub|Kim, Seong-Jin|Choi, Kyeong Sook
PMID: 15208664
Journal: J Hepatol. 2004 Jul;41(1):104-11.
Title: Focal adhesion kinase is overexpressed in hepatocellular carcinoma and can be served as an independent prognostic factor.
Author: Fujii, Tsutomu|Koshikawa, Katsumi|Nomoto, Shuji|Okochi, Osamu|Kaneko, Tetsuya|Inoue, Soichiro|Yatabe, Yasushi|Takeda, Shin|Nakao, Akimasa
PMID: 15246215
Journal: Mol Cell Biochem. 2004 Jul;262(1-2):25-33.
Title: Study of the PTEN gene expression and FAK phosphorylation in human hepatocarcinoma tissues and cell lines.
Author: Zhang, Lineng|Yu, Qiang|He, Jianyu|Zha, Xiliang
PMID: 15532706
Journal: Oncogene. 2005 Sep 22;24(42):6406-17.
Title: Methylation silencing of SOCS-3 promotes cell growth and migration by enhancing JAK/STAT and FAK signalings in human hepatocellular carcinoma.
Author: Niwa, Yasuharu|Kanda, Hiroaki|Shikauchi, Yuko|Saiura, Akio|Matsubara, Kenichi|Kitagawa, Tomoyuki|Yamamoto, Junji|Kubo, Takahiko|Yoshikawa, Hirohide
PMID: 16007195
Journal: Cancer Biol Ther. 2005 Aug;4(8):874-82.
Title: PE, a new sulfated saponin from sea cucumber, exhibits anti-angiogenic and anti-tumor activities in vitro and in vivo.
Author: Tian, Fang|Zhang, Xiongwen|Tong, Yunguang|Yi, Yanghua|Zhang, Shilong|Li, Ling|Sun, Peng|Lin, Liping|Ding, Jian
PMID: 16082187
Journal: World J Gastroenterol. 2005 Aug 14;11(30):4667-73.
Title: Role of cell adhesion signal molecules in hepatocellular carcinoma cell apoptosis.
Author: Su, Jian-Min|Wang, Li-Ying|Liang, Yu-Long|Zha, Xi-Liang
PMID: 16094707
Journal: World J Gastroenterol. 2005 Nov 7;11(41):6512-7.
Title: Genistein inhibits invasive potential of human hepatocellular carcinoma by altering cell cycle, apoptosis, and angiogenesis.
Author: Gu, Yan|Zhu, Chen-Fang|Iwamoto, Hitoshi|Chen, Ji-Sheng
PMID: 16425425
Journal: Life Sci. 2006 May 8;78(24):2826-32.
Title: Epigallocatechin gallate reduces hypoxia-induced apoptosis in human hepatoma cells.
Author: Park, Hae Jeong|Shin, Dong-Hoon|Chung, Woo Jin|Leem, Kanghyun|Yoon, Seo Hyun|Hong, Mee Suk|Chung, Joo-Ho|Bae, Jae-Hoon|Hwang, Jae Seok
PMID: 16445947
Journal: Cancer Lett. 2007 Mar 18;247(2):336-44.
Title: siRNA targeted against HAb18G/CD147 inhibits MMP-2 secretion, actin and FAK expression in hepatocellular carcinoma cell line via ERK1/2 pathway.
Author: Xu, Hui-Yun|Qian, Ai-Rong|Shang, Peng|Xu, Jing|Kong, Ling-Min|Bian, Hui-Jie|Chen, Zhi-Nan
PMID: 16815629
Journal: Biochem Biophys Res Commun. 2007 Mar 30;355(1):72-7.
Title: DLC-1, a GTPase-activating protein for Rho, is associated with cell proliferation, morphology, and migration in human hepatocellular carcinoma.
Author: Kim, Tai Young|Lee, Jung Weon|Kim, Hwang-Phill|Jong, Hyun-Soon|Kim, Tae-You|Jung, Mira|Bang, Yung-Jue
PMID: 17292327
Journal: Br J Cancer. 2007 Jul 2;97(1):50-7.
Title: The significance of proline-rich tyrosine kinase2 (Pyk2) on hepatocellular carcinoma progression and recurrence.
Author: Sun, C K|Ng, K T|Sun, B S|Ho, J W Y|Lee, T K|Ng, I|Poon, R T P|Lo, C M|Liu, C L|Man, K|Fan, S T
PMID: 17551499
Journal: Zhonghua Yi Xue Za Zhi. 2007 May 15;87(18):1256-9.
Title: [Focal adhesion kinase mRNA overexpression in hepatocellular carcinoma HCC) and correlation thereof with prognosis of HCC].
Author: Yuan, Zhou|Fan, Jia|Wu, Zhi-quan|Zhou, Jian|Qiu, Shuang-jian
PMID: 17686260
Journal: Anticancer Res. 2007 Jul-Aug;27(4B):2377-84.
Title: Crude extracts of Euchresta formosana radix inhibit invasion and migration of human hepatocellular carcinoma cells.
Author: Hsu, Shu-Chun|Kuo, Chao-Lin|Lin, Jing-Pin|Lee, Jau-Hong|Lin, Chin-Chung|Su, Chin-Cheng|Yang, Mei-Due|Chung, Jing-Gung
PMID: 17695528
Journal: Mol Cell Proteomics. 2007 Dec;6(12):2150-64.
Title: A proteomics analysis of cell signaling alterations in colorectal cancer.
Author: Madoz-Gurpide, Juan|Canamero, Marta|Sanchez, Lydia|Solano, Jose|Alfonso, Patricia|Casal, J Ignacio
PMID: 17848589
Journal: Zhonghua Wai Ke Za Zhi. 2007 Oct 1;45(19):1350-3.
Title: [The role of FAK expression inhibition by RNA interference on liver cancer cells].
Author: Yuan, Zhou|Zheng, Qi|Huang, Xin-yu|Fan, Jia
PMID: 18241574
Journal: J Cell Biochem. 2008 Jan 1;103(1):9-20.
Title: Reduction of PKC alpha decreases cell proliferation, migration, and invasion of human malignant hepatocellular carcinoma.
Author: Wu, Trang-Tiau|Hsieh, Yi-Hsien|Hsieh, Yih-Shou|Liu, Jer-Yuh
PMID: 17486587
Journal: Mol Carcinog. 2008 Dec;47(12):956-63.
Title: Carbonic anhydrase III promotes transformation and invasion capability in hepatoma cells through FAK signaling pathway.
Author: Dai, Huei-Yue|Hong, Chih-Chen|Liang, San-Chi|Yan, Ming-De|Lai, Gi-Ming|Cheng, Ann-Lii|Chuang, Shuang-En
PMID: 18444244
Journal: BMC Cancer. 2008 Jul 23;8:206.
Title: ENMD-1198, a novel tubulin-binding agent reduces HIF-1alpha and STAT3 activity in human hepatocellular carcinoma(HCC) cells, and inhibits growth and vascularization in vivo.
Author: Moser, Christian|Lang, Sven A|Mori, Akira|Hellerbrand, Claus|Schlitt, Hans J|Geissler, Edward K|Fogler, William E|Stoeltzing, Oliver
PMID: 18651980
Journal: J Exp Clin Cancer Res. 2008 Oct 11;27:50.
Title: Downregulation of CD147 expression alters cytoskeleton architecture and inhibits gelatinase production and SAPK pathway in human hepatocellular carcinoma cells.
Author: Qian, Ai-Rong|Zhang, Wei|Cao, Jian-Ping|Yang, Peng-Fei|Gao, Xiang|Wang, Zhe|Xu, Hui-Yun|Weng, Yuan-Yuan|Shang, Peng
PMID: 18847500
Journal: J Biol Chem. 2008 Dec 19;283(51):35598-605.
Title: MR-1 modulates proliferation and migration of human hepatoma HepG2 cells through myosin light chains-2 (MLC2)/focal adhesion kinase (FAK)/Akt signaling pathway.
Author: Ren, Kaihuan|Jin, Haixia|Bian, Chunjing|He, Hongwei|Liu, Xia|Zhang, Shenghua|Wang, Yiguang|Shao, Rong-guang
PMID: 18948272
Journal: Med Oncol. 2009 Dec;26(4):409-14.
Title: Overexpression and significance of focal adhesion kinase in hepatocellular carcinoma and its relationship with HBV infection.
Author: Cai, Lei|Han, Juan|Zhuo, Xianlu|Xiong, Yan|Dong, Jiahong|Li, Xiaowu
PMID: 19021002
Journal: Cell Biol Int. 2009 Feb;33(2):199-206.
Title: Enhanced expression of Hab18g/CD147 and activation of integrin pathway in HCC cells under 3-D co-culture conditions.
Author: Wu, Ya-Mei|Tang, Juan|Zhao, Pu|Chen, Zhi-Nan|Jiang, Jian-Li
PMID: 19059491
Journal: Exp Mol Pathol. 2009 Oct;87(2):133-40.
Title: Morphological changes and molecular expressions of hepatocellular carcinoma cells in three-dimensional culture model.
Author: Wu, Ya-Mei|Tang, Juan|Zhao, Pu|Chen, Zhi-Nan|Jiang, Jian-Li
PMID: 19615356
Journal: Hepatology. 2009 Dec;50(6):1839-50.
Title: Novel role for epidermal growth factor-like domain 7 in metastasis of human hepatocellular carcinoma.
Author: Wu, Fan|Yang, Lian-Yue|Li, Yun-Feng|Ou, Di-Peng|Chen, Dong-Ping|Fan, Chun
PMID: 19824075
Journal: BMC Cancer. 2010 Jan 19;10:20.
Title: Grp78 promotes the invasion of hepatocellular carcinoma.
Author: Su, Rongjian|Li, Zhen|Li, Hongdan|Song, Huijuan|Bao, Cuifen|Wei, Jia|Cheng, Liufang
PMID: 20082722
Journal: Clin Exp Metastasis. 2010 Feb;27(2):71-82.
Title: FAK is involved in invasion and metastasis of hepatocellular carcinoma.
Author: Chen, Jing-Song|Huang, Xiao-Hui|Wang, Qian|Chen, Xi-Lin|Fu, Xin-Hui|Tan, Hao-Xiang|Zhang, Long-Juan|Li, Wen|Bi, Jiong
PMID: 20180147
Journal: Nat Cell Biol. 2010 Apr;12(4):390-9.
Title: Gain of miR-151 on chromosome 8q24.3 facilitates tumour cell migration and spreading through downregulating RhoGDIA.
Author: Ding, Jie|Huang, Shenglin|Wu, Shunquan|Zhao, Yingjun|Liang, Linhui|Yan, Mingxia|Ge, Chao|Yao, Jian|Chen, Taoyang|Wan, Dafang|Wang, Hongyang|Gu, Jianren|Yao, Ming|Li, Jinjun|Tu, Hong|He, Xianghuo
PMID: 20305651
Journal: Hepatology. 2010 Sep;52(3):1164-6.
Title: MicroRNA-151 and its hosting gene FAK (focal adhesion kinase) regulate tumor cell migration and spreading of hepatocellular carcinoma.
Author: Luedde, Tom
PMID: 20812359
Journal: Hepatology. 2010 Dec;52(6):2012-22.
Title: Thrombin is a therapeutic target for metastatic osteopontin-positive hepatocellular carcinoma.
Author: Xue, Yu-Hua|Zhang, Xiao-Fei|Dong, Qiong-Zhu|Sun, Jian|Dai, Chun|Zhou, Hai-Jun|Ren, Ning|Jia, Hu-Liang|Ye, Qin-Hai|Qin, Lun-Xiu
PMID: 20890897
Journal: Cancer Chemother Pharmacol. 2011 Jul;68(1):79-86.
Title: Kinase activation profile associated with TGF-beta-dependent migration of HCC cells: a preclinical study.
Author: Fransvea, Emilia|Mazzocca, Antonio|Santamato, Angela|Azzariti, Amalia|Antonaci, Salvatore|Giannelli, Gianluigi
PMID: 20844878
Journal: Zhonghua Gan Zang Bing Za Zhi. 2011 Jan;19(1):48-51.
Title: [Relative analysis of OPN and its related signal molecules in hepatocellular carcinoma].
Author: Zhang, Lan|Li, Hai-yu|Yin, Xiao-lu|Xu, Yan-ping|Chen, Yi|Xie, Xiao-ying|Shen, Yue-fang|Ye, Qing-hai|Ren, Zheng-gang
PMID: 21272459
Journal: PLoS One. 2011 Apr 20;6(4):e18878.
Title: Proline-rich tyrosine kinase 2 (Pyk2) promotes cell motility of hepatocellular carcinoma through induction of epithelial to mesenchymal transition.
Author: Sun, Chris K|Ng, Kevin T|Lim, Zophia X|Cheng, Qiao|Lo, Chung Mau|Poon, Ronnie T|Man, Kwan|Wong, Nathalie|Fan, Sheung Tat
PMID: 21533080
Journal: Hepatology. 2011 Dec;54(6):2012-24.
Title: HAb18G/CD147 promotes cell motility by regulating annexin II-activated RhoA and Rac1 signaling pathways in hepatocellular carcinoma cells.
Author: Zhao, Pu|Zhang, Wei|Wang, Shi-Jie|Yu, Xiao-Ling|Tang, Juan|Huang, Wan|Li, Yong|Cui, Hong-Yong|Guo, Yun-Shan|Tavernier, Jan|Zhang, Si-He|Jiang, Jian-Li|Chen, Zhi-Nan
PMID: 21809360
Journal: Sichuan Da Xue Xue Bao Yi Xue Ban. 2011 Jul;42(4):455-60.
Title: [RNA interference targeting focal adhesion kinase inhibited the growth of human hepatocellular carcinoma sk-hep-1].
Author: Xu, Wen-Jing|Zhang, Shuang|Zhang, Na|Yang, Yang|Wei, Yu-Quan|Deng, Hong-Xin
PMID: 21866625
Journal: Virchows Arch. 2011 Nov;459(5):465-75.
Title: Periostin expression and epithelial-mesenchymal transition in cancer: a review and an update.
Author: Morra, Laura|Moch, Holger
PMID: 21997759
Journal: J Exp Clin Cancer Res. 2012 Apr 30;31:39.
Title: Knockdown of glucose-regulated protein 78 decreases the invasion, metalloproteinase expression and ECM degradation in hepatocellular carcinoma cells.
Author: Li, Hongdan|Song, Huijuan|Luo, Junsheng|Liang, Jia|Zhao, Song|Su, Rongjian
PMID: 22546345
Journal: Cell Death Differ. 2012 Nov;19(11):1779-90.
Title: CD147 induces UPR to inhibit apoptosis and chemosensitivity by increasing the transcription of Bip in hepatocellular carcinoma.
Author: Tang, J|Guo, Y-S|Zhang, Y|Yu, X-L|Li, L|Huang, W|Li, Y|Chen, B|Jiang, J-L|Chen, Z-N
PMID: 22595757
Journal: Phytochemistry. 2012 Aug;80:64-9.
Title: Ajugalide-B (ATMA) is an anoikis-inducing agent from Ajuga taiwanensis with antiproliferative activity against tumor cells in vitro.
Author: Chiou, Chun-Tang|Kuo, Yao-Haur|Chan, Yu-Yi|Juang, Shin-Hun|Chan, Hsiu-Hui|Wu, Tian-Shung
PMID: 22633845
Journal: FEBS J. 2012 Oct;279(20):3898-910.
Title: Knockdown of lactate dehydrogenase A suppresses tumor growth and metastasis of human hepatocellular carcinoma.
Author: Sheng, Shi L|Liu, Jian J|Dai, Yun H|Sun, Xiao G|Xiong, Xiao P|Huang, Gang
PMID: 22897481
Journal: PLoS One. 2012;7(8):e44147.
Title: Focal adhesion kinase (FAK) mediates the induction of pro-oncogenic and fibrogenic phenotypes in hepatitis C virus (HCV)-infected cells.
Author: Alisi, Anna|Arciello, Mario|Petrini, Stefania|Conti, Beatrice|Missale, Gabriele|Balsano, Clara
PMID: 22937161
Journal: Int J Oncol. 2012 Nov;41(5):1635-42.
Title: Inhibitory effects of Yangzheng Xiaoji on angiogenesis and the role of the focal adhesion kinase pathway.
Author: Jiang, Wen G|Ye, Lin|Ji, Ke|Frewer, Natasha|Ji, Jiafu|Mason, Malcolm D
PMID: 22971748
Journal: Carcinogenesis. 2013 Jan;34(1):10-9.
Title: Sonic hedgehog signaling pathway induces cell migration and invasion through focal adhesion kinase/AKT signaling-mediated activation of matrix metalloproteinase (MMP)-2 and MMP-9 in liver cancer.
Author: Chen, Jing-Song|Huang, Xiao-hui|Wang, Qian|Huang, Jiong-Qiang|Zhang, Long-juan|Chen, Xi-Lin|Lei, Jian|Cheng, Zhi-Xiang
PMID: 22948179
Journal: Hepatology. 2013 May;57(5):1906-18.
Title: Argonaute2 promotes tumor metastasis by way of up-regulating focal adhesion kinase expression in hepatocellular carcinoma.
Author: Cheng, Na|Li, Yandong|Han, Ze-Guang
PMID: 23258480
Journal: Hepatology. 2013 Jun;57(6):2326-37.
Title: BTB/POZ domain-containing protein 7: epithelial-mesenchymal transition promoter and prognostic biomarker of hepatocellular carcinoma.
Author: Tao, Yi-Ming|Huang, Jin-Lin|Zeng, Shan|Zhang, Sai|Fan, Xue-Gong|Wang, Zhi-Ming|Yang, Hui-Xiang|Yuan, Xiao-Hua|Wang, Pu|Wu, Fan|Luo, Jia|Zeng, De-Yu|Shen, Hong
PMID: 23325674
Journal: Int J Oncol. 2013 May;42(5):1833-41.
Title: Prostaglandin E(2) receptor EP1-mediated phosphorylation of focal adhesion kinase enhances cell adhesion and migration in hepatocellular carcinoma cells.
Author: Bai, Xiaoming|Wang, Jie|Zhang, Li|Ma, Juan|Zhang, Hai|Xia, Shukai|Zhang, Min|Ma, Xiuping|Guo, Yan|Rong, Rong|Cheng, Shanyu|Shu, Wei|Wang, Yipin|Leng, Jing
PMID: 23525457
Journal: Transl Oncol. 2013 Apr;6(2):206-15. Epub 2013 Apr 1.
Title: FAK Inhibition Decreases Hepatoblastoma Survival Both In Vitro and In Vivo.
Author: Gillory, Lauren A|Stewart, Jerry E|Megison, Michael L|Nabers, Hugh C|Mroczek-Musulman, Elizabeth|Beierle, Elizabeth A
PMID: 23544173
Journal: Biochem Biophys Res Commun. 2013 Apr 26;434(1):35-41.
Title: The blockage of Ras/ERK pathway augments the sensitivity of SphK1 inhibitor SKI II in human hepatoma HepG2 cells.
Author: Zhang, Caixia|He, Hongwei|Zhang, Hao|Yu, Dongke|Zhao, Wuli|Chen, Yi|Shao, Rongguang
PMID: 23545258
Journal: BMC Cancer. 2013 May 30;13:267.
Title: Molecular mechanisms of action and potential biomarkers of growth inhibition of dasatinib (BMS-354825) on hepatocellular carcinoma cells.
Author: Chang, Alex Y|Wang, Miao
PMID: 23721490
Journal: Acta Pharmacol Sin. 2013 Dec;34(12):1554-9.
Title: Oligomannurarate sulfate inhibits CXCL12/SDF-1-mediated proliferation and invasion of human tumor cells in vitro.
Author: Wen, Wei-wei|Xie, Shao|Xin, Xian-liang|Geng, Mei-yu|Ding, Jian|Chen, Yi
PMID: 24141568
Journal: Mol Carcinog. 2014 Apr;53(4):325-36.
Title: Downregulation of JWA promotes tumor invasion and predicts poor prognosis in human hepatocellular carcinoma.
Author: Wu, Xiaofeng|Chen, Hairong|Gao, Qiang|Bai, Jin|Wang, Xiaoying|Zhou, Jian|Qiu, Shuangjian|Xu, Yang|Shi, Yinghong|Wang, Xuehao|Zhou, Jianwei|Fan, Jia
PMID: 23169062
Journal: Oncol Rep. 2014 Feb;31(2):641-8.
Title: Activated hepatic stellate cells promote hepatocellular carcinoma cell migration and invasion via the activation of FAK-MMP9 signaling.
Author: Han, Shaoshan|Han, Lei|Yao, Yingmin|Sun, Hao|Zan, Xianfeng|Liu, Qingguang
PMID: 24284889
Journal: Breast Cancer Res Treat. 2014 Jan;143(1):33-45.
Title: Adeno-associated virus-mediated expression of recombinant CBD-HepII polypeptide of human fibronectin inhibits metastasis of breast cancer.
Author: He, Zhen-Hui|Lei, Zhang|Zhen, Yan|Gong, Wei|Huang, Bo|Yuan, Ye|Zhang, Gui-Mei|Wang, Xiao-Juan|Feng, Zuo-Hua
PMID: 24288120
Journal: Cancer Lett. 2014 Apr 1;345(1):91-9.
Title: CD68(+)HLA-DR(+) M1-like macrophages promote motility of HCC cells via NF-kappaB/FAK pathway.
Author: Wang, Hao|Wang, Xianteng|Li, Xia|Fan, Yuchen|Li, Guosheng|Guo, Chun|Zhu, Faliang|Zhang, Lining|Shi, Yongyu
PMID: 24333724
Journal: Int J Med Sci. 2014 Jan 21;11(3):268-75.
Title: Role of overexpression of MACC1 and/or FAK in predicting prognosis of hepatocellular carcinoma after liver transplantation.
Author: Gao, Sheng|Lin, Bing-Yi|Yang, Zhe|Zheng, Zhi-Yun|Liu, Zhi-Kun|Wu, Li-Ming|Xie, Hai-Yang|Zhou, Lin|Zheng, Shu-Sen
PMID: 24516351
Journal: Int J Cancer. 2014 Dec 15;135(12):2972-83.
Title: A preclinical evaluation of a novel multikinase inhibitor, SKLB-329, as a therapeutic agent against hepatocellular carcinoma.
Author: Zhong, Lei|Fu, Xiao-Yu|Zou, Chan|Yang, Ling-Ling|Zhou, Shu|Yang, Jiao|Tang, Yun|Cheng, Chuan|Li, Lin-Li|Xiang, Rong|Chen, Li-Juan|Chen, Yu-Zong|Wei, Yu-Quan|Yang, Sheng-Yong
PMID: 24789676
Journal: Asian Pac J Cancer Prev. 2014;15(7):3045-50.
Title: Targeting EGFL7 expression through RNA interference suppresses renal cell carcinoma growth by inhibiting angiogenesis.
Author: Xu, Han-Feng|Chen, Lei|Liu, Xian-Dong|Zhan, Yun-Hong|Zhang, Hui-Hui|Li, Qing|Wu, Bin
PMID: 24815445
Journal: J Pathol. 2014 Nov;234(3):316-28.
Title: Capn4 contributes to tumour growth and metastasis of hepatocellular carcinoma by activation of the FAK-Src signalling pathways.
Author: Dai, Zhi|Zhou, Shao-Lai|Zhou, Zheng-Jun|Bai, Dou-Sheng|Xu, Xiao-Yu|Fu, Xiu-Tao|Chen, Qing|Zhao, Yi-Ming|Zhu, Kai|Yu, Lei|Yang, Guo-Huan|Wang, Zheng|Wu, Wei-Zhong|Zhou, Jian|Fan, Jia
PMID: 24962955
Journal: J Transl Med. 2014 Jul 4;12:190.
Title: Full-length soluble CD147 promotes MMP-2 expression and is a potential serological marker in detection of hepatocellular carcinoma.
Author: Wu, Jiao|Hao, Zhi-Wei|Zhao, You-Xu|Yang, Xiang-Min|Tang, Hao|Zhang, Xin|Song, Fei|Sun, Xiu-Xuan|Wang, Bin|Nan, Gang|Chen, Zhi-Nan|Bian, Huijie
PMID: 24996644
Journal: Pathol Res Pract. 2014 Oct;210(10):668-74.
Title: Association of CD98, integrin beta1, integrin beta3 and Fak with the progression and liver metastases of colorectal cancer.
Author: Sun, Cuicui|Zargham, Ramin|Shao, Qin|Gui, Xianyong|Marcus, Victoria|Lazaris, Anthoula|Salman, Ayat|Metrakos, Peter|Qu, Xianjun|Gao, Zuhua
PMID: 25041835
Journal: Int J Mol Med. 2014 Oct;34(4):1081-6.
Title: Downregulation of Notch1 inhibits the invasion of human hepatocellular carcinoma HepG2 and MHCC97H cells through the regulation of PTEN and FAK.
Author: Hu, Yan-Jian|Li, Hong-Ying|Qiu, Kai-Jie|Li, Da-Chuan|Zhou, Jia-Hui|Hu, Yan-Hua|Zhang, Feng-Min
PMID: 25110169
Journal: PLoS One. 2014 Aug 29;9(8):e105245.
Title: Down-regulation of 5-HT1B and 5-HT1D receptors inhibits proliferation, clonogenicity and invasion of human pancreatic cancer cells.
Author: Gurbuz, Nilgun|Ashour, Ahmed A|Alpay, S Neslihan|Ozpolat, Bulent
PMID: 25170871
Journal: Mar Drugs. 2014 Sep 12;12(9):4783-98.
Title: 11-epi-Sinulariolide acetate reduces cell migration and invasion of human hepatocellular carcinoma by reducing the activation of ERK1/2, p38MAPK and FAK/PI3K/AKT/mTOR signaling pathways.
Author: Lin, Jen-Jie|Su, Jui-Hsin|Tsai, Chi-Chu|Chen, Yi-Jen|Liao, Ming-Hui|Wu, Yu-Jen
PMID: 25222667
Journal: PLoS One. 2014 Sep 30;9(9):e110067.
Title: Down-regulation of 5-HT1B and 5-HT1D receptors inhibits proliferation, clonogenicity and invasion of human pancreatic cancer cells.
Author: Gurbuz, Nilgun|Ashour, Ahmed A|Alpay, S Neslihan|Ozpolat, Bulent
PMID: 25268648
Journal: Mol Cancer. 2014 Oct 1;13:226.
Title: Elevated autocrine EDIL3 protects hepatocellular carcinoma from anoikis through RGD-mediated integrin activation.
Author: Feng, Ming-Xuan|Ma, Ming-Ze|Fu, Ying|Li, Jun|Wang, Tao|Xue, Feng|Zhang, Jian-Jun|Qin, Wen-Xin|Gu, Jian-Ren|Zhang, Zhi-Gang|Xia, Qiang
PMID: 25273699
Journal: Environ Toxicol. 2015 Jan;30(1):74-82.
Title: Bufalin inhibits migration and invasion in human hepatocellular carcinoma SK-Hep1 cells through the inhibitions of NF-kB and matrix metalloproteinase-2/-9-signaling pathways.
Author: Chen, Ya-Yin|Lu, Hsu-Feng|Hsu, Shu-Chun|Kuo, Chao-Lin|Chang, Shu-Jen|Lin, Jen-Jyh|Wu, Ping-Ping|Liu, Jia-You|Lee, Ching-Hsiao|Chung, Jing-Gung|Chang, Jin-Biou
PMID: 23949904
Journal: Hepatology. 2015 Jan;61(1):214-26.
Title: FAK is required for c-Met/beta-catenin-driven hepatocarcinogenesis.
Author: Shang, Na|Arteaga, Maribel|Zaidi, Ali|Stauffer, Jimmy|Cotler, Scott J|Zeleznik-Le, Nancy J|Zhang, Jiwang|Qiu, Wei
PMID: 25163657
Journal: Clin Exp Metastasis. 2015 Jan;32(1):39-53.
Title: A chimeric antibody targeting CD147 inhibits hepatocellular carcinoma cell motility via FAK-PI3K-Akt-Girdin signaling pathway.
Author: Wang, Yuan|Yuan, Lin|Yang, Xiang-Min|Wei, Ding|Wang, Bin|Sun, Xiu-Xuan|Feng, Fei|Nan, Gang|Wang, Ye|Chen, Zhi-Nan|Bian, Huijie
PMID: 25424030
Journal: Mol Cancer Ther. 2015 Feb;14(2):553-63.
Title: HAb18G/CD147 promotes radioresistance in hepatocellular carcinoma cells: a potential role for integrin beta1 signaling.
Author: Wu, Jiao|Li, Yong|Dang, Ya-Zheng|Gao, Hong-Xiang|Jiang, Jian-Li|Chen, Zhi-Nan
PMID: 25534361
Journal: Oncotarget. 2015 Jan 30;6(3):1707-22.
Title: Cytotoxic activity of the novel small molecule AKT inhibitor SC66 in hepatocellular carcinoma cells.
Author: Cusimano, Antonella|Puleio, Roberto|D'Alessandro, Natale|Loria, Guido R|McCubrey, James A|Montalto, Giuseppe|Cervello, Melchiorre
PMID: 25596737
Journal: Oncotarget. 2015 Mar 30;6(9):6811-24.
Title: The histidine-rich calcium binding protein (HRC) promotes tumor metastasis in hepatocellular carcinoma and is upregulated by SATB1.
Author: Liu, Jingmei|Han, Ping|Li, Mengke|Yan, Wei|Liu, Jin|Liu, Jiqiao|He, Jiayi|Tu, Wei|Xia, Yujia|Zhou, Zhenzhen|Gong, Jin|Liu, Mei|Ding, Qiang|Tian, Dean
PMID: 25762622
Journal: Cancer Cell Int. 2015 Mar 7;15:29.
Title: Transient knockdown-mediated deficiency in plectin alters hepatocellular motility in association with activated FAK and Rac1-GTPase.
Author: Cheng, Chiung-Chi|Lai, Yen-Chang Clark|Lai, Yih-Shyong|Hsu, Yung-Hsiang|Chao, Wei-Ting|Sia, Kee-Chin|Tseng, Yu-Hui|Liu, Yi-Hsiang
PMID: 25774093
Journal: Med Oncol. 2015 Apr;32(4):125.
Title: The effects of focal adhesion kinase on the motility, proliferation and apoptosis of Caco2 and SMMC-7721 cells.
Author: Gao, Ning|He, Huimin|Xiao, Li|Gao, Xiaojie|Shi, Hongyan|Wu, Qiong|Xu, Nan|Lei, Yuqing|Song, Xigui|Hou, Yingchun
PMID: 25790781
Journal: Mol Cancer. 2015 Mar 24;14:64.
Title: The role of TGFBI (betaig-H3) in gastrointestinal tract tumorigenesis.
Author: Han, Bing|Cai, Haolei|Chen, Ying|Hu, Bing|Luo, Hongyu|Wu, Yulian|Wu, Jiangping
PMID: 25889002
Journal: J Agric Food Chem. 2015 May 13;63(18):4561-9.
Title: Antcin K, an Active Triterpenoid from the Fruiting Bodies of Basswood-Cultivated Antrodia cinnamomea, Inhibits Metastasis via Suppression of Integrin-Mediated Adhesion, Migration, and Invasion in Human Hepatoma Cells.
Author: Huang, Ya-Ling|Chu, Yung-Lin|Ho, Chi-Tang|Chung, Jing-Gung|Lai, Chiao-I|Su, Yu-Cheng|Kuo, Yueh-Hsiung|Sheen, Lee-Yan
PMID: 25911944
Journal: Oncotarget. 2015 Jun 20;6(17):15050-64.
Title: Thyroid hormone-mediated regulation of lipocalin 2 through the Met/FAK pathway in liver cancer.
Author: Chung, I-Hsiao|Chen, Cheng-Yi|Lin, Yang-Hsiang|Chi, Hsiang-Cheng|Huang, Ya-Hui|Tai, Pei-Ju|Liao, Chia-Jung|Tsai, Chung-Ying|Lin, Syuan-Ling|Wu, Meng-Han|Chen, Ching-Ying|Lin, Kwang-Huei
PMID: 25940797
Journal: BMC Cancer. 2015 May 10;15:389.
Title: The role of c-Src in the invasion and metastasis of hepatocellular carcinoma cells induced by association of cell surface GRP78 with activated alpha2M.
Author: Zhao, Song|Li, Hongdan|Wang, Qingjun|Su, Chang|Wang, Guan|Song, Huijuan|Zhao, Liang|Luan, Zhidong|Su, Rongjian
PMID: 25958313
Journal: PLoS One. 2015 May 15;10(5):e0126725.
Title: Corosolic Acid Inhibits Hepatocellular Carcinoma Cell Migration by Targeting the VEGFR2/Src/FAK Pathway.
Author: Ku, Chung-Yu|Wang, Ying-Ren|Lin, Hsuan-Yuan|Lu, Shao-Chun|Lin, Jung-Yaw
PMID: 25978354
Journal: Oncotarget. 2015 Sep 15;6(27):23776-92.
Title: 3'3-Diindolylmethane inhibits migration, invasion and metastasis of hepatocellular carcinoma by suppressing FAK signaling.
Author: Li, Wen-Xue|Chen, Li-Ping|Sun, Min-Ying|Li, Jun-Tao|Liu, Hua-Zhang|Zhu, Wei
PMID: 26068982
Journal: Int J Oncol. 2015 Aug;47(2):668-78.
Title: Gene therapy targeting hepatocellular carcinoma by a dual-regulated oncolytic adenovirus harboring the focal adhesion kinase shRNA.
Author: Gao, Yang|Zhu, Yayun|Huang, Xinyu|Ai, Kaixing|Zheng, Qi|Yuan, Zhou
PMID: 26081241
Journal: J Transl Med. 2015 Jul 22;13:237.
Title: MRC-5 fibroblast-conditioned medium influences multiple pathways regulating invasion, migration, proliferation, and apoptosis in hepatocellular carcinoma.
Author: Ding, Songming|Chen, Guoliang|Zhang, Wu|Xing, Chunyang|Xu, Xiao|Xie, Haiyang|Lu, Aili|Chen, Kangjie|Guo, Haijun|Ren, Zhigang|Zheng, Shusen|Zhou, Lin
PMID: 26198300
Journal: Oncotarget. 2015 Oct 27;6(33):34831-45.
Title: CD147 reinforces [Ca2+]i oscillations and promotes oncogenic progression in hepatocellular carcinoma.
Author: Tang, Juan|Guo, Yun-Shan|Yu, Xiao-Ling|Huang, Wan|Zheng, Ming|Zhou, Ying-Hui|Nan, Gang|Wang, Jian-Chao|Yang, Hai-Jiao|Yu, Jing-Min|Jiang, Jian-Li|Chen, Zhi-Nan
PMID: 26498680
Journal: Am J Chin Med. 2015;43(8):1671-96.
Title: Antrodia cinnamomea Inhibits Migration in Human Hepatocellular Carcinoma Cells: The Role of ERp57 and PGK-1.
Author: Chen, Ying-Yi|Liu, Fon-Chang|Wu, Tian-Shung|Sheu, Ming-Jyh
PMID: 26621448
Journal: Tumour Biol. 2016 Mar;37(3):3341-7.
Title: Overexpression of Rab5a promotes hepatocellular carcinoma cell proliferation and invasion via FAK signaling pathway.
Author: Geng, Donghua|Zhao, Wenyan|Feng, Yong|Liu, Jingang
PMID: 26443539
Journal: Oncotarget. 2016 Mar 22;7(12):14742-54.
Title: A20 inhibits the motility of HCC cells induced by TNF-alpha.
Author: Wang, Xianteng|Ma, Chao|Zong, Zhaoyun|Xiao, Ying|Li, Na|Guo, Chun|Zhang, Lining|Shi, Yongyu
PMID: 26909601
Journal: Oncotarget. 2016 Apr 5;7(14):18229-46.
Title: Liver fatty acid-binding protein (L-FABP) promotes cellular angiogenesis and migration in hepatocellular carcinoma.
Author: Ku, Chung-Yu|Liu, Yu-Huei|Lin, Hsuan-Yuan|Lu, Shao-Chun|Lin, Jung-Yaw
PMID: 26919097
Journal: Cancer Lett. 2016 May 28;375(1):73-83.
Title: MicroRNA-379-5p inhibits tumor invasion and metastasis by targeting FAK/AKT signaling in hepatocellular carcinoma.
Author: Chen, Jing-Song|Li, Hua-Shu|Huang, Jiong-Qiang|Dong, Shi-Hao|Huang, Zhi-Jie|Yi, Wei|Zhan, Gao-Fang|Feng, Ju-Tao|Sun, Jian-Cong|Huang, Xiao-Hui
PMID: 26944318
Journal: Cancer Lett. 2016 Jun 28;376(1):188-96.
Title: An integrin beta4-EGFR unit promotes hepatocellular carcinoma lung metastases by enhancing anchorage independence through activation of FAK-AKT pathway.
Author: Leng, Chao|Zhang, Zhan-Guo|Chen, Wei-Xun|Luo, Hong-Ping|Song, Jia|Dong, Wei|Zhu, Xuan-Ru|Chen, Xiao-Ping|Liang, Hui-Fang|Zhang, Bi-Xiang
PMID: 26996299
Journal: Cell Death Dis. 2016 Apr 21;7:e2201.
Title: Galectin-1 induces hepatocellular carcinoma EMT and sorafenib resistance by activating FAK/PI3K/AKT signaling.
Author: Zhang, P-F|Li, K-S|Shen, Y-H|Gao, P-T|Dong, Z-R|Cai, J-B|Zhang, C|Huang, X-Y|Tian, M-X|Hu, Z-Q|Gao, D-M|Fan, J|Ke, A-W|Shi, G-M
PMID: 27100895
Journal: Gene Expr. 2016;17(1):79-88.
Title: FAK Kinase Activity Is Required for the Progression of c-MET/beta-Catenin-Driven Hepataocellular Carcinoma.
Author: Shang, Na|Arteaga, Maribel|Zaidi, Ali|Cotler, Scott J|Breslin, Peter|Ding, Xianzhong|Kuo, Paul|Nishimura, Michael|Zhang, Jiwang|Qiu, Wei
PMID: 27142958
Journal: Cancer Res. 2016 Jul 15;76(14):4124-35.
Title: FAP Promotes Immunosuppression by Cancer-Associated Fibroblasts in the Tumor Microenvironment via STAT3-CCL2 Signaling.
Author: Yang, Xuguang|Lin, Yuli|Shi, Yinghong|Li, Bingji|Liu, Weiren|Yin, Wei|Dang, Yongjun|Chu, Yiwei|Fan, Jia|He, Rui
PMID: 27216177
Journal: Oncol Rep. 2016 Sep;36(3):1483-90.
Title: Effect of saracatinib on pulmonary metastases from hepatocellular carcinoma.
Author: Xiong, Ju|Wu, Jin-Sheng|Mao, Shan-Shan|Yu, Xiang-Nan|Huang, Xiao-Xi
PMID: 27460949
Journal: Tumour Biol. 2016 Oct;37(10):13445-13453.
Title: Downregulation of SLC5A8 inhibits hepatocellular carcinoma progression through regulation of Wnt/beta-catenin signaling.
Author: Hu, Ben-Shun|Xiong, Shu-Ming|Li, Gang|Li, Jian-Ping
PMID: 27465549
Journal: PLoS One. 2016 Sep 16;11(9):e0162666.
Title: Prognostic Value of Focal Adhesion Kinase (FAK) in Human Solid Carcinomas: A Meta-Analysis.
Author: Zeng, Xiao-Qing|Li, Na|Ma, Li-Li|Tseng, Yu-Jen|Zhao, Nai-Qing|Chen, Shi-Yao
PMID: 27637100
Journal: Mol Cancer Ther. 2016 Dec;15(12):2916-2925.
Title: CT-707, a Novel FAK Inhibitor, Synergizes with Cabozantinib to Suppress Hepatocellular Carcinoma by Blocking Cabozantinib-Induced FAK Activation.
Author: Wang, Dan-Dan|Chen, Ying|Chen, Zi-Bo|Yan, Fang-Jie|Dai, Xiao-Yang|Ying, Mei-Dan|Cao, Ji|Ma, Jian|Luo, Pei-Hua|Han, Yong-Xin|Peng, Yong|Sun, Ying-Hui|Zhang, Hui|He, Qiao-Jun|Yang, Bo|Zhu, Hong
PMID: 27638856
Journal: Hepatology. 2016 Dec;64(6):2103-2117.
Title: Hepatic stellate cells induce hepatocellular carcinoma cell resistance to sorafenib through the laminin-332/alpha3 integrin axis recovery of focal adhesion kinase ubiquitination.
Author: Azzariti, Amalia|Mancarella, Serena|Porcelli, Letizia|Quatrale, Anna Elisa|Caligiuri, Alessandra|Lupo, Luigi|Dituri, Francesco|Giannelli, Gianluigi
PMID: 27639064
Journal: Cytokine. 2017 Feb;90:44-53.
Title: Silencing IGF-II impairs C-myc and N-ras expressions of SMMC-7721 cells via suppressing FAK/PI3K/Akt signaling pathway.
Author: Ji, Yuanyuan|Wang, Zhidong|Li, Zongfang|Huang, Na|Chen, Haiyan|Li, Baohua|Hui, Bo
PMID: 27768959
Journal: Oncol Rep. 2017 Jan;37(1):259-272.
Title: Immediate early response protein 2 regulates hepatocellular carcinoma cell adhesion and motility via integrin beta1-mediated signaling pathway.
Author: Xu, Zhengxin|Zhu, Lei|Wu, Wenjuan|Liao, Yuexia|Zhang, Weicheng|Deng, Zijing|Shen, Jingyuan|Yuan, Qing|Zheng, Lu|Zhang, Yu|Shen, Weigan
PMID: 27840969
Journal: Oncotarget. 2017 Jan 3;8(1):1714-1724.
Title: NEDD9 may regulate hepatocellular carcinoma cell metastasis by promoting epithelial-mesenchymal-transition and stemness via repressing Smad7.
Author: Wang, Zhipeng|Shen, Min|Lu, Peng|Li, Xiao|Zhu, Shaojun|Yue, Shuqiang
PMID: 27974675
Journal: Oncol Res. 2017 Jul 5;25(6):1001-1008.
Title: Overexpression of RAS-Association Domain Family 6 (RASSF6) Inhibits Proliferation and Tumorigenesis in Hepatocellular Carcinoma Cells.
Author: Zhu, Nan|Si, Mahui|Yang, Ning|Jing, Yingying|Fu, Yong|Zhao, Xijun|Lin, Zhipeng|Yang, Guangshun
PMID: 27983932
Journal: Biochem Biophys Res Commun. 2017 Jan 29;483(1):553-558.
Title: Substrate stiffness promotes latent TGF-beta1 activation in hepatocellular carcinoma.
Author: Pang, Mingshu|Teng, Yao|Huang, Jianyong|Yuan, Yuan|Lin, Feng|Xiong, Chunyang
PMID: 28025149
Journal: Oncol Res. 2017 Jan 2;25(1):19-27.
Title: Knockdown of Rap2B Inhibits the Proliferation and Invasion in Hepatocellular Carcinoma Cells.
Author: Zhang, Li|Duan, Hong-Bin|Yang, Yun-Sheng
PMID: 28081729
Journal: Prostate. 2017 May;77(7):776-793.
Title: The Effect of a Histone Deacetylase Inhibitor (AR-42) on Canine Prostate Cancer Growth and Metastasis.
Author: Elshafae, Said M|Kohart, Nicole A|Altstadt, Lucas A|Dirksen, Wessel P|Rosol, Thomas J
PMID: 28181686
Journal: Theranostics. 2017 Jan 11;7(3):594-613.
Title: Anti-cancer Activity of Novel TM4SF5-Targeting Antibodies through TM4SF5 Neutralization and Immune Cell-Mediated Cytotoxicity.
Author: Ahn, Hye-Mi|Ryu, Jihye|Song, Jin Myeong|Lee, Yunhee|Kim, Hye-Jin|Ko, Dongjoon|Choi, Inpyo|Kim, Sang Jick|Lee, Jung Weon|Kim, Semi
PMID: 28255353
Journal: Cell Death Differ. 2017 May;24(5):889-902.
Title: Focal adhesion kinase depletion reduces human hepatocellular carcinoma growth by repressing enhancer of zeste homolog 2.
Author: Gnani, Daniela|Romito, Ilaria|Artuso, Simona|Chierici, Marco|De Stefanis, Cristiano|Panera, Nadia|Crudele, Annalisa|Ceccarelli, Sara|Carcarino, Elena|D'Oria, Valentina|Porru, Manuela|Giorda, Ezio|Ferrari, Karin|Miele, Luca|Villa, Erica|Balsano, Clara|Pasi
PMID: 28338656
Journal: Int J Oncol. 2017 May;50(5):1749-1759.
Title: Transglutaminase 2 is upregulated in primary hepatocellular carcinoma with early recurrence as determined by proteomic profiles.
Author: Yamaguchi, Hiromi|Kuroda, Kazumichi|Sugitani, Masahiko|Takayama, Tadatoshi|Hasegawa, Kiyoshi|Esumi, Mariko
PMID: 28339069
Journal: Toxicology. 2017 Jun 1;384:1-10.
Title: Salinomycin attenuates liver cancer stem cell motility by enhancing cell stiffness and increasing F-actin formation via the FAK-ERK1/2 signalling pathway.
Author: Sun, Jinghui|Luo, Qing|Liu, Lingling|Yang, Xianjiong|Zhu, Shunqin|Song, Guanbin
PMID: 28395993
Journal: Oncotarget. 2017 May 9;8(19):31745-31757.
Title: MiR-425-5p promotes invasion and metastasis of hepatocellular carcinoma cells through SCAI-mediated dysregulation of multiple signaling pathways.
Author: Fang, Feng|Song, Tianqiang|Zhang, Ti|Cui, Yunlong|Zhang, Gewen|Xiong, Qingqing
PMID: 28423650
Journal: Biochem Biophys Res Commun. 2017 Jun 10;487(4):782-788.
Title: Dual sphingosine kinase inhibitor SKI-II enhances sensitivity to 5-fluorouracil in hepatocellular carcinoma cells via suppression of osteopontin and FAK/IGF-1R signalling.
Author: Grbcic, Petra|Tomljanovic, Ivana|Klobucar, Marko|Kraljevic Pavelic, Sandra|Lucin, Ksenija|Sedic, Mirela
PMID: 28433634
Journal: Biomed Pharmacother. 2017 Sep;93:398-405.
Title: SRPX2, an independent prognostic marker, promotes cell migration and invasion in hepatocellular carcinoma.
Author: Lin, Xiaobo|Chang, Weiping|Wang, Yuan|Tian, Ming|Yu, Zhaoxiang
PMID: 28654796
Journal: Sci Rep. 2017 Jul 12;7(1):5189.
Title: Quantitative proteomics reveal the anti-tumour mechanism of the carbohydrate recognition domain of Galectin-3 in Hepatocellular carcinoma.
Author: Wang, Mingchao|Tian, Fang|Ying, Wantao|Qian, Xiaohong
PMID: 28701735
Journal: Cancer Res. 2017 Nov 1;77(21):5831-5845.
Title: ANGPTL1 Interacts with Integrin alpha1beta1 to Suppress HCC Angiogenesis and Metastasis by Inhibiting JAK2/STAT3 Signaling.
Author: Yan, Qian|Jiang, Lingxi|Liu, Ming|Yu, Dandan|Zhang, Yu|Li, Yan|Fang, Shuo|Li, Yan|Zhu, Ying-Hui|Yuan, Yun-Fei|Guan, Xin-Yuan
PMID: 28904065
Journal: Carcinogenesis. 2017 Sep 1;38(9):910-919.
Title: OCIAD2 suppressed tumor growth and invasion via AKT pathway in Hepatocelluar carcinoma.
Author: Wu, Dan|Yang, Xufang|Peng, Huiming|Guo, Dongmin|Zhao, Weiling|Zhao, Chen|Zhou, Xiaobo
PMID: 28911005
Journal: Sci Rep. 2017 Sep 14;7(1):11563.
Title: Inhibition of fucosylation by 2-fluorofucose suppresses human liver cancer HepG2 cell proliferation and migration as well as tumor formation.
Author: Zhou, Ying|Fukuda, Tomohiko|Hang, Qinglei|Hou, Sicong|Isaji, Tomoya|Kameyama, Akihiko|Gu, Jianguo
PMID: 28912543
Journal: Biomed Pharmacother. 2017 Nov;95:1844-1852.
Title: Connexin 32 affects doxorubicin resistance in hepatocellular carcinoma cells mediated by Src/FAK signaling pathway.
Author: Yu, Meiling|Zou, Qi|Wu, Xiaoxiang|Han, Guangshu|Tong, Xuhui
PMID: 28968929
Journal: Sci Rep. 2017 Oct 16;7(1):13201.
Title: Cell-surface major vault protein promotes cancer progression through harboring mesenchymal and intermediate circulating tumor cells in hepatocellular carcinomas.
Author: Lee, Hyun Min|Joh, Jae Won|Seo, Se-Ri|Kim, Won-Tae|Kim, Min Kyu|Choi, Hong Seo|Kim, So Young|Jang, Young-Joo|Sinn, Dong Hyun|Choi, Gyu Seong|Kim, Jong Man|Kwon, Choon Hyuck David|Chang, Hee Jin|Kim, Dae Shick|Ryu, Chun Jeih
PMID: 29038587
Journal: Oncotarget. 2017 Jun 27;8(41):69577-69593.
Title: Cross-talk mechanism between endothelial cells and hepatocellular carcinoma cells via growth factors and integrin pathway promotes tumor angiogenesis and cell migration.
Author: Feng, Tang|Yu, Hongchi|Xia, Qing|Ma, Yunlong|Yin, Hongmei|Shen, Yang|Liu, Xiaoheng
PMID: 29050226
Journal: J BUON. 2017 Sep-Oct;22(5):1097-1106.
Title: FAK, Src and p-Paxillin expression is decreased in liver metastasis of colorectal carcinoma patients.
Author: Mantonakis, Eleftherios|Giaginis, Constantinos|Pikoulis, Emmanouel|Felekouras, Evangelos|Patsouris, Efstratios|Liakakos, Theodoros|Papalampros, Efstathios|Theocharis, Stamatios
PMID: 29135089
Journal: J Cancer. 2017 Oct 17;8(18):3742-3754.
Title: Insufficient Radiofrequency Ablation Treated Hepatocellular Carcinoma Cells Promote Metastasis by Up-Regulation ITGB3.
Author: Zhang, Ning|Ma, Dening|Wang, Lu|Zhu, Xiaodong|Pan, Qi|Zhao, Yiming|Zhu, Weiping|Zhou, Jiamin|Wang, Longrong|Chai, Zongtao|Ao, Jianyang|Sun, Huichuan|Tang, Zhaoyou
PMID: 29151962
Journal: Oncotarget. 2017 Oct 5;8(56):95586-95595.
Title: Collagen I promotes hepatocellular carcinoma cell proliferation by regulating integrin beta1/FAK signaling pathway in nonalcoholic fatty liver.
Author: Zheng, Xinglong|Liu, Wenyan|Xiang, Junxi|Liu, Peng|Ke, Mengyun|Wang, Bo|Wu, Rongqian|Lv, Yi
PMID: 29221151
Journal: Cell Adh Migr. 2018 Jan 2;12(1):56-68.
Title: Fluid shear stress regulates HepG2 cell migration though time-dependent integrin signaling cascade.
Author: Yu, Hongchi|Shen, Yang|Jin, Jingsi|Zhang, Yingying|Feng, Tang|Liu, Xiaoheng
PMID: 28636424
Journal: J Drug Target. 2018 Sep;26(8):643-648.
Title: Myofibrillogenesis regulator 1 (MR-1): a potential therapeutic target for cancer and PNKD.
Author: Wang, Junxia|Zhao, Wuli|Liu, Hong|He, Hongwei|Shao, Rongguang
PMID: 29103325
Journal: Liver Int. 2018 Jul;38(7):1263-1272.
Title: Mitochondrial fission promotes cell migration by Ca(2+) /CaMKII/ERK/FAK pathway in hepatocellular carcinoma.
Author: Sun, Xiacheng|Cao, Haiyan|Zhan, Lei|Yin, Chun|Wang, Gang|Liang, Ping|Li, Jibin|Wang, Zhe|Liu, Bingrong|Huang, Qichao|Xing, Jinliang
PMID: 29210177
Journal: J Int Med Res. 2018 Apr;46(4):1311-1325.
Title: beta1 integrin-mediated multicellular resistance in hepatocellular carcinoma through activation of the FAK/Akt pathway.
Author: Tian, Tao|Li, Chun-Li|Fu, Xiao|Wang, Shu-Hong|Lu, Jun|Guo, Hui|Yao, Yu|Nan, Ke-Jun|Yang, Yu-Juan
PMID: 29332411
Journal: BMC Complement Altern Med. 2018 Jan 16;18(1):17.
Title: Herbal formula YGJDSJ inhibits anchorage-independent growth and induces anoikis in hepatocellular carcinoma Bel-7402 cells.
Author: Hu, Bing|Zhang, Tong|An, Hong-Mei|Zheng, Jia-Lu|Yan, Xia|Huang, Xiao-Wei
PMID: 29338725
Journal: Biochem Pharmacol. 2018 Apr;150:191-201.
Title: Natural small molecule bigelovin suppresses orthotopic colorectal tumor growth and inhibits colorectal cancer metastasis via IL6/STAT3 pathway.
Author: Li, Mingyue|Yue, Grace Gar-Lee|Song, Li-Hua|Huang, Mao-Bo|Lee, Julia Kin-Ming|Tsui, Stephen Kwok-Wing|Fung, Kwok-Pui|Tan, Ning-Hua|Lau, Clara Bik-San
PMID: 29454618
Journal: J Exp Clin Cancer Res. 2018 Mar 5;37(1):46.
Title: CADM2, as a new target of miR-10b, promotes tumor metastasis through FAK/AKT pathway in hepatocellular carcinoma.
Author: Li, Dongliang|Zhang, Yongjian|Zhang, He|Zhan, Chao|Li, Xin|Ba, Tu|Qiu, Zini|E, Fang|Lv, Guixiang|Zou, Chendan|Wang, Chuxuan|Si, Lining|Zou, Chaoxia|Li, Qiang|Gao, Xu
PMID: 29506532
Journal: Cancer Lett. 2018 Jul 28;427:1-8.
Title: Low-level shear stress promotes migration of liver cancer stem cells via the FAK-ERK1/2 signalling pathway.
Author: Sun, Jinghui|Luo, Qing|Liu, Lingling|Song, Guanbin
PMID: 29678550
Journal: Cancer Lett. 2018 Aug 10;429:29-40.
Title: CD31 regulates metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma via the ITGB1-FAK-Akt signaling pathway.
Author: Zhang, Yuan-Yuan|Kong, Ling-Qun|Zhu, Xiao-Dong|Cai, Hao|Wang, Cheng-Hao|Shi, Wen-Kai|Cao, Man-Qing|Li, Xiao-Long|Li, Kang-Shuai|Zhang, Shi-Zhe|Chai, Zong-Tao|Ao, Jian-Yang|Ye, Bo-Gen|Sun, Hui-Chuan
PMID: 29746931
Journal: Biomed Pharmacother. 2018 Jul;103:1632-1642.
Title: miR-300 regulates the epithelial-mesenchymal transition and invasion of hepatocellular carcinoma by targeting the FAK/PI3K/AKT signaling pathway.
Author: Wang, Rongchang|Yu, Zheng|Chen, Fan|Xu, Hongxu|Shen, Shunli|Chen, Wei|Chen, Lianzhou|Su, Qiao|Zhang, Longjuan|Bi, Jiong|Zeng, Wentao|Li, Wen|Huang, Xiaohui|Wang, Qian
PMID: 29864952
Journal: NPJ Precis Oncol. 2018 Jan 23;2(1):2.
Title: Vasodilator-stimulated phosphoprotein promotes liver metastasis of gastrointestinal cancer by activating a beta1-integrin-FAK-YAP1/TAZ signaling pathway.
Author: Xiang, Xiaoyu|Wang, Yuanguo|Zhang, Hongbin|Piao, Jinhua|Muthusamy, Selvaraj|Wang, Lei|Deng, Yibin|Zhang, Wei|Kuang, Rui|Billadeau, Daniel D|Huang, Shengbing|Lai, Jinping|Urrutia, Raul|Kang, Ningling
PMID: 29872721
Journal: J Immunol Res. 2018 May 24;2018:4602570.
Title: Integrin alpha9 Suppresses Hepatocellular Carcinoma Metastasis by Rho GTPase Signaling.
Author: Zhang, Yan-Li|Xing, Xin|Cai, Li-Bo|Zhu, Lei|Yang, Xiao-Mei|Wang, Ya-Hui|Yang, Qin|Nie, Hui-Zhen|Zhang, Zhi-Gang|Li, Jun|Zhang, Xue-Li
PMID: 29951557
Journal: Exp Cell Res. 2018 Sep 15;370(2):373-382.
Title: ADAM17 promotes cell migration and invasion through the integrin beta1 pathway in hepatocellular carcinoma.
Author: Li, Yong|Ren, Zhen|Wang, Yu|Dang, Ya-Zheng|Meng, Bo-Xiang|Wang, Guo-Dong|Zhang, Jing|Wu, Jiao|Wen, Ning
PMID: 29966664
Journal: Biomed Pharmacother. 2018 Nov;107:824-833.
Title: LncRNA DBH-AS1 facilitates the tumorigenesis of hepatocellular carcinoma by targeting miR-138 via FAK/Src/ERK pathway.
Author: Bao, Jie|Chen, Xiaoqi|Hou, Yuge|Kang, Gailing|Li, Qiaoli|Xu, Yun
PMID: 30142544
Journal: Life Sci. 2018 Oct 4. pii: S0024-3205(18)30619-2.
Title: Inhibition of SRC/FAK cue: A novel pathway for the synergistic effect of rosuvastatin on the anti-cancer effect of dasatinib in hepatocellular carcinoma.
Author: El Sayed, Ibrahim|Helmy, Maged W|El-Abhar, Hanan S
PMID: 30292831
Journal: Cancer Med. 2018 Oct 28.
Title: Focal adhesion kinase activation limits efficacy of Dasatinib in c-Myc driven hepatocellular carcinoma.
Author: Liu, Xianqiong|Song, Xinhua|Zhang, Jie|Xu, Zhong|Che, Li|Qiao, Yu|Ortiz Pedraza, Yunuen|Cigliano, Antonio|Pascale, Rosa M|Calvisi, Diego F|Liu, Yanju|Chen, Xin
PMID: 30370649