Literatures

Primary Site >> Colorectal Cancer

Gene >> PTK2

1.
Journal:	Cancer Biochem Biophys. 1996 Apr;15(3):127-39.
Title:	Correlations between the expression, phosphotyrosine content and enzymatic activity of focal adhesion kinase, pp125FAK, in tumor and nontransformed cells.
Author:	Withers, B E\|Hanks, S K\|Fry, D W
PMID:	8937737

2.
Journal:	J Biol Chem. 1997 Jan 24;272(4):2534-41.
Title:	Activities of the microtubule-stabilizing agents epothilones A and B with purified tubulin and in cells resistant to paclitaxel (Taxol(R)).
Author:	Kowalski, R J\|Giannakakou, P\|Hamel, E
PMID:	8999970

3.
Journal:	Oncogene. 1997 Jan 23;14(3):283-93.
Title:	A role for epidermal growth factor receptor, c-Src and focal adhesion kinase in an in vitro model for the progression of colon cancer.
Author:	Brunton, V G\|Ozanne, B W\|Paraskeva, C\|Frame, M C
PMID:	9018114

4.
Journal:	Ann Surg Oncol. 1997 Apr-May;4(3):264-8.
Title:	Overexpression of focal adhesion kinase (p125FAK) in human colorectal carcinoma liver metastases: independence from c-src or c-yes activation.
Author:	Han, N M\|Fleming, R Y\|Curley, S A\|Gallick, G E
PMID:	9142389

5.
Journal:	Int J Cancer. 1998 Mar 30;76(1):91-8.
Title:	De novo expression of the alpha5beta1-fibronectin receptor in HT29 colon-cancer cells reduces activity of C-SRC. Increase of C-SRC activity by attachment on fibronectin.
Author:	Schmidt, R\|Streit, M\|Kaiser, R\|Herzberg, F\|Schirner, M\|Schramm, K\|Kaufmann, C\|Henneken, M\|Schafer-Korting, M\|Thiel, E\|Kreuser, E D
PMID:	9533767

6.
Journal:	Differentiation. 1998 Mar;62(5):249-57.
Title:	Acquisition of cell adhesion and induction of focal adhesion kinase of human colon cancer Colo 201 cells by retinoic acid-induced differentiation.
Author:	Nakagawa, K\|Sogo, S\|Hioki, K\|Tokunaga, R\|Taketani, S
PMID:	9566310

7.
Journal:	Dig Dis Sci. 1998 Jul;43(7):1454-64.
Title:	Analysis of signaling protein kinases in human colon or colorectal carcinomas.
Author:	Licato, L L\|Brenner, D A
PMID:	9690379

8.
Journal:	Cell Struct Funct. 1998 Oct;23(5):255-64.
Title:	Rapid adhesion and spread of non-adherent colon cancer Colo201 cells induced by the protein kinase inhibitors, K252a and KT5720 and suppression of the adhesion by the immunosuppressants FK506 and cyclosporin A.
Author:	Mohri, T\|Kameshita, I\|Suzuki, S\|Hioki, K\|Tokunaga, R\|Takatani, S
PMID:	9872566

9.
Journal:	Oncogene. 1999 Oct 7;18(41):5646-53.
Title:	Increased dosage and amplification of the focal adhesion kinase gene in human cancer cells.
Author:	Agochiya, M\|Brunton, V G\|Owens, D W\|Parkinson, E K\|Paraskeva, C\|Keith, W N\|Frame, M C
PMID:	10523844

10.
Journal:	Clin Exp Metastasis. 1999;17(8):713-21.
Title:	Role of the cytoskeleton in adhesion stabilization of human colorectal carcinoma cells to extracellular matrix components under dynamic conditions of laminar flow.
Author:	Haier, J\|Nicolson, G L
PMID:	10919716

11.
Journal:	Clin Cancer Res. 2000 Mar;6(3):949-56.
Title:	Colon cancer chemopreventive drugs modulate integrin-mediated signaling pathways.
Author:	Weyant, M J\|Carothers, A M\|Bertagnolli, M E\|Bertagnolli, M M
PMID:	10741720

12.
Journal:	Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2000 Apr;17(2):119-21.
Title:	[Effect of laminin antisense RNA on the expression of five intracellular proteins stimulated by transforming growth factor beta(1)].
Author:	Liu, B\|Liu, W\|Ning, G
PMID:	10751536

13.
Journal:	Clin Cancer Res. 2000 Jun;6(6):2417-23.
Title:	Immunohistochemical analyses of focal adhesion kinase expression in benign and malignant human breast and colon tissues: correlation with preinvasive and invasive phenotypes.
Author:	Cance, W G\|Harris, J E\|Iacocca, M V\|Roche, E\|Yang, X\|Chang, J\|Simkins, S\|Xu, L
PMID:	10873094

14.
Journal:	Anticancer Res. 2000 Jul-Aug;20(4):2265-71.
Title:	Time-dependent dephosphorylation through serine/threonine phosphatases is required for stable adhesion of highly and poorly metastatic HT-29 colon carcinoma cell lines to collagen.
Author:	Haier, J\|Nicolson, G L
PMID:	10953284

15.
Journal:	Cancer Res. 2001 Jan 1;61(1):118-25.
Title:	(+)-Catechin inhibits intestinal tumor formation and suppresses focal adhesion kinase activation in the min/+ mouse.
Author:	Weyant, M J\|Carothers, A M\|Dannenberg, A J\|Bertagnolli, M M
PMID:	11196148

16.
Journal:	Neoplasia. 2001 May-Jun;3(3):215-26.
Title:	The protrusive phase and full development of integrin-dependent adhesions in colon epithelial cells require FAK- and ERK-mediated actin spike formation: deregulation in cancer cells.
Author:	Brunton, V G\|Fincham, V J\|McLean, G W\|Winder, S J\|Paraskeva, C\|Marshall, J F\|Frame, M C
PMID:	11494115

17.
Journal:	Int J Cancer. 2002 Jan 20;97(3):336-43.
Title:	CD151 enhances cell motility and metastasis of cancer cells in the presence of focal adhesion kinase.
Author:	Kohno, Masashi\|Hasegawa, Hitoshi\|Miyake, Masayuki\|Yamamoto, Tadashi\|Fujita, Shigeru
PMID:	11774285

18.
Journal:	Oncogene. 2002 Feb 21;21(9):1450-60.
Title:	PTEN regulates tumor cell adhesion of colon carcinoma cells under dynamic conditions of fluid flow.
Author:	Haier, Jorg\|Nicolson, Garth L
PMID:	11857088

19.
Journal:	Cancer Res. 2002 May 1;62(9):2669-74.
Title:	Increased Src activity disrupts cadherin/catenin-mediated homotypic adhesion in human colon cancer and transformed rodent cells.
Author:	Irby, Rosalyn B\|Yeatman, Timothy J
PMID:	11980666

20.
Journal:	World J Gastroenterol. 2002 Aug;8(4):613-8.
Title:	Expression of focal adhesion kinase and alpha5 and beta1 integrins in carcinomas and its clinical significance.
Author:	Su, Jian-Min\|Gui, Lu\|Zhou, Yi-Ping\|Zha, Xi-Liang
PMID:	12174366

21.
Journal:	FASEB J. 2002 Oct;16(12):1642-4.
Title:	Codon 12 and codon 13 mutations at the K-ras gene induce different soft tissue sarcoma types in nude mice.
Author:	Guerrero, Silvia\|Figueras, Agnes\|Casanova, Isolda\|Farre, Lourdes\|Lloveras, Belen\|Capella, Gabriel\|Trias, Manuel\|Mangues, Ramon
PMID:	12207005

22.
Journal:	J Exp Ther Oncol. 2002 Jul-Aug;2(4):237-45.
Title:	Src protein kinase pp60c-src influences adhesion stabilization of HT-29 colon carcinoma cells to extracellular matrix components under dynamic conditions of laminar flow.
Author:	Haier, Jorg\|Gallick, Garry E\|Nicolson, Garth L
PMID:	12416028

23.
Journal:	Clin Cancer Res. 2003 Jan;9(1):215-22.
Title:	Overexpression of focal adhesion kinase in primary colorectal carcinomas and colorectal liver metastases: immunohistochemistry and real-time PCR analyses.
Author:	Lark, Amy L\|Livasy, Chad A\|Calvo, Benjamin\|Caskey, Laura\|Moore, Dominic T\|Yang, XiHui\|Cance, William G
PMID:	12538472

24.
Journal:	Mol Cancer Ther. 2003 May;2(5):461-9.
Title:	Src family kinase activity is required for signal tranducer and activator of transcription 3 and focal adhesion kinase phosphorylation and vascular endothelial growth factor signaling in vivo and for anchorage-dependent and -independent growth of human tu
Author:	Laird, A Douglas\|Li, Guangmin\|Moss, Katherine G\|Blake, Robert A\|Broome, Martin A\|Cherrington, Julie M\|Mendel, Dirk B
PMID:	12748308

25.
Journal:	J Histochem Cytochem. 2003 Aug;51(8):1041-8.
Title:	Expression of GRP and its receptor in well-differentiated colon cancer cells correlates with the presence of focal adhesion kinase phosphorylated at tyrosines 397 and 407.
Author:	Matkowskyj, Kristina A\|Keller, Kristin\|Glover, Sarah\|Kornberg, Lori\|Tran-Son-Tay, Roger\|Benya, Richard V
PMID:	12871985

26.
Journal:	Cell Physiol Biochem. 2003;13(3):135-46.
Title:	Absence of adhesion triggers differential FAK and SAPKp38 signals in SW620 human colon cancer cells that may inhibit adhesiveness and lead to cell death.
Author:	Walsh, Mary F\|Thamilselvan, Vijayalakshmi\|Grotelueschen, Rainer\|Farhana, Lulu\|Basson, Marc
PMID:	12876384

27.
Journal:	Mol Cancer Res. 2003 Aug;1(10):755-64.
Title:	Simultaneous inhibition of focal adhesion kinase and SRC enhances detachment and apoptosis in colon cancer cell lines.
Author:	Golubovskaya, Vita M\|Gross, Steven\|Kaur, Aparna S\|Wilson, Richard I\|Xu, Li-Hui\|Yang, Xi Hui\|Cance, William G
PMID:	12939401

28.
Journal:	Eur J Surg Oncol. 2003 Sep;29(7):571-4.
Title:	Focal adhesion kinase expression is not a prognostic predictor in colon adenocarcinoma patients.
Author:	Theocharis, S E\|Kouraklis, G P\|Kakisis, J D\|Kanelli, H G\|Apostolakou, F E\|Karatzas, G M\|Koutselinis, A S
PMID:	12943621

29.
Journal:	Gene Ther. 2003 Nov;10(23):1961-9.
Title:	Adenovirus-mediated transfer of the PTEN gene inhibits human colorectal cancer growth in vitro and in vivo.
Author:	Saito, Y\|Swanson, X\|Mhashilkar, A M\|Oida, Y\|Schrock, R\|Branch, C D\|Chada, S\|Zumstein, L\|Ramesh, R
PMID:	14528320

30.
Journal:	Biochem Pharmacol. 2004 Jan 1;67(1):135-46.
Title:	Rapid tyrosine phosphorylation of focal adhesion kinase, paxillin, and p130Cas by gastrin in human colon cancer cells.
Author:	Yu, Hong-Gang\|Schrader, Henning\|Otte, Jan-Michel\|Schmidt, Wolfgang E\|Schmitz, Frank
PMID:	14667936

31.
Journal:	Gastroenterology. 2004 Jan;126(1):8-18.
Title:	Pressure activates colon cancer cell adhesion by inside-out focal adhesion complex and actin cytoskeletal signaling.
Author:	Thamilselvan, Vijayalakshmi\|Basson, Marc D
PMID:	14699482

32.
Journal:	Oncogene. 2004 Jan 8;23(1):289-97.
Title:	Csk defines the ability of integrin-mediated cell adhesion and migration in human colon cancer cells: implication for a potential role in cancer metastasis.
Author:	Rengifo-Cam, William\|Konishi, Akio\|Morishita, Naoki\|Matsuoka, Hidetada\|Yamori, Takao\|Nada, Shigeyuki\|Okada, Masato
PMID:	14712234

33.
Journal:	J Cell Physiol. 2004 Apr;199(1):77-88.
Title:	Phosphorylation of focal adhesion kinase tyrosine 397 critically mediates gastrin-releasing peptide's morphogenic properties.
Author:	Glover, Sarah\|Delaney, Melissa\|Dematte, Cecile\|Kornberg, Lori\|Frasco, Melissa\|Tran-Son-Tay, Roger\|Benya, Richard V
PMID:	14978737

34.
Journal:	Oncogene. 2004 Jul 15;23(32):5558-61.
Title:	Transforming growth factor beta regulates cell-cell adhesion through extracellular matrix remodeling and activation of focal adhesion kinase in human colon carcinoma Moser cells.
Author:	Wang, Hongmei\|Radjendirane, Venugopal\|Wary, Kishore K\|Chakrabarty, Subhas
PMID:	15133493

35.
Journal:	Exp Cell Res. 2004 Sep 10;299(1):236-47.
Title:	Integrity of actin fibers and microtubules influences metastatic tumor cell adhesion.
Author:	Korb, Timo\|Schluter, Kerstin\|Enns, Andreas\|Spiegel, Hans-Ulrich\|Senninger, Norbert\|Nicolson, Garth L\|Haier, Jorg
PMID:	15302590

36.
Journal:	Nat Neurosci. 2004 Nov;7(11):1204-12. Epub 2004 Oct 17.
Title:	Focal adhesion kinase in netrin-1 signaling.
Author:	Ren, Xiu-Rong\|Ming, Guo-Li\|Xie, Yi\|Hong, Yan\|Sun, Dong-Mei\|Zhao, Zhong-Qiu\|Feng, Zhu\|Wang, Qiang\|Shim, Sangwoo\|Chen, Zhou-Feng\|Song, Hong-Jun\|Mei, Lin\|Xiong, Wen-Cheng
PMID:	15494733

37.
Journal:	Cancer Res. 2005 Feb 15;65(4):1335-42.
Title:	Identification of Src-specific phosphorylation site on focal adhesion kinase: dissection of the role of Src SH2 and catalytic functions and their consequences for tumor cell behavior.
Author:	Brunton, Valerie G\|Avizienyte, Egle\|Fincham, Valerie J\|Serrels, Bryan\|Metcalf, Chester A 3rd\|Sawyer, Tomi K\|Frame, Margaret C
PMID:	15735019

38.
Journal:	Cell Oncol. 2005;27(1):57-65.
Title:	DNA copy number changes at 8q11-24 in metastasized colorectal cancer.
Author:	Buffart, T E\|Coffa, J\|Hermsen, M A J A\|Carvalho, B\|van der Sijp, J R M\|Ylstra, B\|Pals, G\|Schouten, J P\|Meijer, G A
PMID:	15750208

39.
Journal:	J Biol Chem. 2005 Jul 1;280(26):25008-21. Epub 2005 Apr 25.
Title:	Direct interaction of the N-terminal domain of focal adhesion kinase with the N-terminal transactivation domain of p53.
Author:	Golubovskaya, Vita M\|Finch, Richard\|Cance, William G
PMID:	15855171

40.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2005 Jun;288(6):G1274-82.
Title:	Transient upregulation of GRP and its receptor critically regulate colon cancer cell motility during remodeling.
Author:	Glover, Sarah\|Nathaniel, Rajkumar\|Shakir, Lubna\|Perrault, Cecile\|Anderson, Rebecca K\|Tran-Son-Tay, Roger\|Benya, Richard V
PMID:	15890713

41.
Journal:	Carcinogenesis. 2005 Oct;26(10):1687-97. Epub 2005 May 25.
Title:	The role of the cytoskeleton in differentially regulating pressure-mediated effects on malignant colonocyte focal adhesion signaling and cell adhesion.
Author:	Thamilselvan, Vijayalakshmi\|Basson, Marc D
PMID:	15917311

42.
Journal:	Zhonghua Zhong Liu Za Zhi. 2005 Apr;27(4):213-5.
Title:	[Effect of gastrin on invasiveness of human colon cancer cells].
Author:	Ding, Jian\|Yu, Jie-ping\|Li, Dan\|Yu, Hong-gang\|Luo, He-sheng\|Wei, Wen-zhou
PMID:	15949418

43.
Journal:	Cell Signal. 2005 Dec;17(12):1505-15.
Title:	Valine-286 residue in the third intracellular loop of the cholecystokinin 2 receptor exerts a pivotal role in cholecystokinin 2 receptor mediated intracellular signal transduction in human colon cancer cells.
Author:	Yu, Hong-Gang\|Schafer, Heiner\|Mergler, Stefan\|Muerkoster, Susanne\|Cramer, Torsten\|Hocker, Michael\|Herzig, Karl-Heinz\|Schmidt, Wolfgang E\|Schmitz, Frank
PMID:	15951156

44.
Journal:	Mol Carcinog. 2005 Aug;43(4):207-14.
Title:	Butyrate regulates the expression of c-Src and focal adhesion kinase and inhibits cell invasion of human colon cancer cells.
Author:	Lee, Jenq-Chang\|Maa, Ming-Chei\|Yu, Hsiu-Shan\|Wang, Jung-Hui\|Yen, Chia-Kuang\|Wang, Shan-Tair\|Chen, Yen-Jen\|Liu, Yuan\|Jin, Ying-Tai\|Leu, Tzeng-Horng
PMID:	16001424

45.
Journal:	Zhonghua Nei Ke Za Zhi. 2005 Jun;44(6):434-7.
Title:	[A study of gastrin-focal adhesion kinase signal pathway in human colon cancer cells].
Author:	Ding, Jian\|Yu, Jie-ping\|Li, Dan\|Luo, He-sheng\|Yu, Hong-gang
PMID:	16008856

46.
Journal:	J Cell Biochem. 2005 Sep 1;96(1):155-69.
Title:	Garcinol modulates tyrosine phosphorylation of FAK and subsequently induces apoptosis through down-regulation of Src, ERK, and Akt survival signaling in human colon cancer cells.
Author:	Liao, Chiung-Ho\|Sang, Shengmin\|Ho, Chi-Tang\|Lin, Jen-Kun
PMID:	16052481

47.
Journal:	Cancer Res. 2005 Nov 1;65(21):9899-905.
Title:	Focal adhesion kinase regulates syndecan-2-mediated tumorigenic activity of HT1080 fibrosarcoma cells.
Author:	Park, Haein\|Han, Innoc\|Kwon, Ho Jeong\|Oh, Eok-Soo
PMID:	16267014

48.
Journal:	Biochem J. 2006 Mar 15;394(Pt 3):647-56.
Title:	Plasma-membrane-associated sialidase (NEU3) differentially regulates integrin-mediated cell proliferation through laminin- and fibronectin-derived signalling.
Author:	Kato, Kengo\|Shiga, Kiyoto\|Yamaguchi, Kazunori\|Hata, Keiko\|Kobayashi, Toshimitsu\|Miyazaki, Kaoru\|Saijo, Shigeru\|Miyagi, Taeko
PMID:	16241905

49.
Journal:	Int J Cancer. 2006 May 15;118(10):2381-9.
Title:	Celecoxib induces anoikis in human colon carcinoma cells associated with the deregulation of focal adhesions and nuclear translocation of p130Cas.
Author:	Casanova, Isolda\|Parreno, Matilde\|Farre, Lourdes\|Guerrero, Silvia\|Cespedes, M Virtudes\|Pavon, Miguel Angel\|Sancho, Francesc J\|Marcuello, Eugenio\|Trias, Manuel\|Mangues, Ramon
PMID:	16353145

50.
Journal:	J Cell Sci. 2006 Jan 1;119(Pt 1):47-55.
Title:	FAK and Src kinases are required for netrin-induced tyrosine phosphorylation of UNC5.
Author:	Li, Weiquan\|Aurandt, Jennifer\|Jurgensen, Claudia\|Rao, Yi\|Guan, Kun-Liang
PMID:	16371650

51.
Journal:	J Biol Chem. 2006 Mar 31;281(13):8497-510. Epub 2006 Feb 3.
Title:	Integrin alpha2-mediated ERK and calpain activation play a critical role in cell adhesion and motility via focal adhesion kinase signaling: identification of a novel signaling pathway.
Author:	Sawhney, Rajinder S\|Cookson, Michelle M\|Omar, Yasin\|Hauser, Jennie\|Brattain, Michael G
PMID:	16461767

52.
Journal:	Anticancer Res. 2006 Mar-Apr;26(2A):1029-37.
Title:	EGF receptor-related protein (ERRP) inhibits invasion of colon cancer cells and tubule formation by endothelial cells in vitro.
Author:	Rishi, Arun K\|Parikh, Rakesh\|Wali, Anil\|Durko, Lukasz\|Zhang, Liyue\|Yu, Yingjie\|Majumdar, Adhip P N
PMID:	16619503

53.
Journal:	Cancer Biol Ther. 2006 Sep;5(9):1169-78. Epub 2006 Sep 6.
Title:	Extracellular pressure stimulates tumor cell adhesion in vitro by paxillin activation.
Author:	van Zyp, J van der Voort\|Conway, W C\|Craig, D H\|van Zyp, N van der Voort\|Thamilselvan, V\|Basson, M D
PMID:	16855384

54.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2006 Sep;291(3):G491-9.
Title:	Focal adhesion kinase protein levels in gut epithelial motility.
Author:	Basson, Marc D\|Sanders, Matthew A\|Gomez, Ruben\|Hatfield, James\|Vanderheide, Richard\|Thamilselvan, Vijayalakshmi\|Zhang, Jianhu\|Walsh, Mary F
PMID:	16899713

55.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2006 Dec;291(6):G1100-12. Epub 2006 Aug
Title:	Deoxycholic acid differentially regulates focal adhesion kinase phosphorylation: role of tyrosine phosphatase ShP2.
Author:	Khare, Sharad\|Holgren, Cory\|Samarel, Allen M
PMID:	16920701

56.
Journal:	Int J Cancer. 2006 Dec 15;119(12):2724-32.
Title:	Enhanced expression of cholecystokinin-2 receptor promotes the progression of colon cancer through activation of focal adhesion kinase.
Author:	Yu, Hong-Gang\|Tong, Shi-Lun\|Ding, You-Ming\|Ding, Jian\|Fang, Xiang-Min\|Zhang, Xian-Feng\|Liu, Zhu-Jun\|Zhou, Yan-Hong\|Liu, Qi-Sheng\|Luo, He-Sheng\|Yu, Jie-Ping
PMID:	16998832

57.
Journal:	Am J Surg. 2006 Nov;192(5):631-5.
Title:	Pressure stimulates breast cancer cell adhesion independently of cell cycle and apoptosis regulatory protein (CARP)-1 regulation of focal adhesion kinase.
Author:	Downey, Christina\|Alwan, Kamal\|Thamilselvan, Vijayalakshmi\|Zhang, Liyue\|Jiang, Yan\|Rishi, Arun K\|Basson, Marc D
PMID:	17071197

58.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2007 Jan;292(1):G182-90. Epub 2006 Aug
Title:	Gastrin-releasing peptide mediates its morphogenic properties in human colon cancer by upregulating intracellular adhesion protein-1 (ICAM-1) via focal adhesion kinase.
Author:	Taglia, Lauren\|Matusiak, Damien\|Matkowskyj, Kristina A\|Benya, Richard V
PMID:	16920698

59.
Journal:	Gynecol Oncol. 2007 Feb;104(2):461-9. Epub 2006 Oct 9.
Title:	L1-CAM in a membrane-bound or soluble form augments protection from apoptosis in ovarian carcinoma cells.
Author:	Stoeck, Alexander\|Gast, Daniela\|Sanderson, Michael P\|Issa, Yasmin\|Gutwein, Paul\|Altevogt, Peter
PMID:	17030349

60.
Journal:	Gastroenterology. 2007 Feb;132(2):645-53.
Title:	A simple method for the routine detection of somatic quantitative genetic alterations in colorectal cancer.
Author:	Killian, Audrey\|Di Fiore, Frederic\|Le Pessot, Florence\|Blanchard, France\|Lamy, Aude\|Raux, Gregory\|Flaman, Jean-Michel\|Paillot, Bernard\|Michel, Pierre\|Sabourin, Jean-Christophe\|Tuech, Jean-Jacques\|Michot, Francis\|Kerckaert, Jean-Pierre\|Sesboue, Richard\|Fre
PMID:	17258723

61.
Journal:	FASEB J. 2007 Jun;21(8):1730-41. Epub 2007 Feb 22.
Title:	FAK association with multiple signal proteins mediates pressure-induced colon cancer cell adhesion via a Src-dependent PI3K/Akt pathway.
Author:	Thamilselvan, Vijayalakshmi\|Craig, David H\|Basson, Marc D
PMID:	17317726

62.
Journal:	Cell Signal. 2007 Aug;19(8):1722-32. Epub 2007 Mar 28.
Title:	Proinvasive activity of BMP-7 through SMAD4/src-independent and ERK/Rac/JNK-dependent signaling pathways in colon cancer cells.
Author:	Grijelmo, Clara\|Rodrigue, Christelle\|Svrcek, Magalie\|Bruyneel, Erik\|Hendrix, An\|de Wever, Olivier\|Gespach, Christian
PMID:	17478078

63.
Journal:	J Biol Chem. 2007 Jul 6;282(27):19399-409. Epub 2007 May 12.
Title:	Eps8 facilitates cellular growth and motility of colon cancer cells by increasing the expression and activity of focal adhesion kinase.
Author:	Maa, Ming-Chei\|Lee, Jenq-Chang\|Chen, Yen-Jen\|Chen, Yun-Ju\|Lee, Yuch-Ching\|Wang, Shan-Tair\|Huang, Ching-Chung\|Chow, Nan-Haw\|Leu, Tzeng-Horng
PMID:	17496330

64.
Journal:	Exp Mol Pathol. 2007 Dec;83(3):443-52.
Title:	Keratinocyte growth factor-transfection-stimulated adhesion of colorectal cancer cells to extracellular matrices.
Author:	Kudo, Mitsuhiro\|Ishiwata, Toshiyuki\|Nakazawa, Nando\|Kawahara, Kiyoko\|Fujii, Takenori\|Teduka, Kiyoshi\|Naito, Zenya
PMID:	17706640

65.
Journal:	Int Rev Cytol. 2007;263:103-53.
Title:	Focal adhesion kinase and p53 signaling in cancer cells.
Author:	Golubovskaya, Vita M\|Cance, William G
PMID:	17725966

66.
Journal:	Zhonghua Yi Xue Za Zhi. 2007 Jun 26;87(24):1704-8.
Title:	[Molecular mechanism of gastrin increasing colon cancer cells' invasion].
Author:	Cao, Jun\|Yu, Jie-ping\|Zhou, Lan\|Song, Wen-chong\|Luo, He-sheng\|Yu, Hong-gang
PMID:	17825155

67.
Journal:	Mol Cell Proteomics. 2007 Dec;6(12):2150-64.
Title:	A proteomics analysis of cell signaling alterations in colorectal cancer.
Author:	Madoz-Gurpide, Juan\|Canamero, Marta\|Sanchez, Lydia\|Solano, Jose\|Alfonso, Patricia\|Casal, J Ignacio
PMID:	17848589

68.
Journal:	Zhonghua Zhong Liu Za Zhi. 2007 May;29(5):346-50.
Title:	[Effects of hFRNK on E-cadherin/beta-catenin in colon cancer cells in vitro].
Author:	Cao, Jun\|Yu, Jie-ping\|Liu, Chao-hong\|Chen, Xin-wen\|Liu, Song\|Luo, He-sheng\|Yu, Hong-gang
PMID:	17892129

69.
Journal:	Am J Physiol Cell Physiol. 2007 Dec;293(6):C1862-74. Epub 2007 Sep 26.
Title:	Alpha-actinin-1 phosphorylation modulates pressure-induced colon cancer cell adhesion through regulation of focal adhesion kinase-Src interaction.
Author:	Craig, David H\|Haimovich, Beatrice\|Basson, Marc D
PMID:	17898132

70.
Journal:	Int J Oncol. 2007 Dec;31(6):1501-8.
Title:	Activation of the FAK-src molecular scaffolds and p130Cas-JNK signaling cascades by alpha1-integrins during colon cancer cell invasion.
Author:	Van Slambrouck, Severine\|Grijelmo, Clara\|De Wever, Olivier\|Bruyneel, Erik\|Emami, Shahin\|Gespach, Christian\|Steelant, Wim F A
PMID:	17982677

71.
Journal:	Eur J Cell Biol. 2008 Jan;87(1):1-16. Epub 2007 Sep 27.
Title:	Focal adhesion kinase mediates defects in the force-dependent reinforcement of initial integrin-cytoskeleton linkages in metastatic colon cancer cell lines.
Author:	von Wichert, Gotz\|Krndija, Denis\|Schmid, Heidrun\|von Wichert, Georg\|Haerter, Georg\|Adler, Guido\|Seufferlein, Thomas\|Sheetz, Michael P
PMID:	17904248

72.
Journal:	Mol Carcinog. 2008 May;47(5):373-82.
Title:	p53 regulates FAK expression in human tumor cells.
Author:	Golubovskaya, Vita M\|Finch, Richard\|Kweh, Frederick\|Massoll, Nicole A\|Campbell-Thompson, Martha\|Wallace, Margaret R\|Cance, William G
PMID:	17999388

73.
Journal:	Neoplasia. 2008 Mar;10(3):287-97.
Title:	Inhibition of JAK1, 2/STAT3 signaling induces apoptosis, cell cycle arrest, and reduces tumor cell invasion in colorectal cancer cells.
Author:	Xiong, Hua\|Zhang, Zhi-Gang\|Tian, Xiao-Qing\|Sun, Dan-Feng\|Liang, Qin-Chuan\|Zhang, Yan-Jie\|Lu, Rong\|Chen, Ying-Xuan\|Fang, Jing-Yuan
PMID:	18320073

74.
Journal:	Cell Mol Life Sci. 2008 May;65(9):1446-57.
Title:	Pressure activates colon cancer cell adhesion via paxillin phosphorylation, Crk, Cas, and Rac1.
Author:	Downey, C\|Craig, D H\|Basson, M D
PMID:	18392556

75.
Journal:	Curr Med Chem. 2008;15(10):978-90.
Title:	ANTI-ADHESION evolves to a promising therapeutic concept in oncology.
Author:	Schmidmaier, R\|Baumann, P
PMID:	18393855

76.
Journal:	Eur J Surg Oncol. 2008 Nov;34(11):1253-61.
Title:	Combined expression of the non-receptor protein tyrosine kinases FAK and Src in primary colorectal cancer is associated with tumor recurrence and metastasis formation.
Author:	de Heer, P\|Koudijs, M M\|van de Velde, C J H\|Aalbers, R I J M\|Tollenaar, R A E M\|Putter, H\|Morreau, J\|van de Water, B\|Kuppen, P J K
PMID:	18556171

77.
Journal:	Gastroenterology. 2008 Aug;135(2):508-17.
Title:	Constitutive CXCL12 expression induces anoikis in colorectal carcinoma cells.
Author:	Wendt, Michael K\|Drury, Luke J\|Vongsa, Rebecca A\|Dwinell, Michael B
PMID:	18558091

78.
Journal:	Eur J Cell Biol. 2008 Sep;87(8-9):569-79.
Title:	Focal adhesion kinase is not required for Src-induced formation of invadopodia in KM12C colon cancer cells and can interfere with their assembly.
Author:	Vitale, Sebastien\|Avizienyte, Egle\|Brunton, Valerie G\|Frame, Margaret C
PMID:	18562041

79.
Journal:	J Clin Invest. 2008 Sep;118(9):3170-80.
Title:	Colchicine inhibits pressure-induced tumor cell implantation within surgical wounds and enhances tumor-free survival in mice.
Author:	Craig, David H\|Owen, Cheri R\|Conway, William C\|Walsh, Mary F\|Downey, Christina\|Basson, Marc D
PMID:	18704196

80.
Journal:	Biochim Biophys Acta. 2008 Dec;1783(12):2323-31.
Title:	Early adhesion induces interaction of FAK and Fyn in lipid domains and activates raft-dependent Akt signaling in SW480 colon cancer cells.
Author:	Baillat, Gilbert\|Siret, Carole\|Delamarre, Estelle\|Luis, Jose
PMID:	18805444

81.
Journal:	Cancer Res. 2008 Oct 15;68(20):8210-20.
Title:	Phosphorylated caveolin-1 regulates Rho/ROCK-dependent focal adhesion dynamics and tumor cell migration and invasion.
Author:	Joshi, Bharat\|Strugnell, Scott S\|Goetz, Jacky G\|Kojic, Liliana D\|Cox, Michael E\|Griffith, Obi L\|Chan, Simon K\|Jones, Steven J\|Leung, Sher-Ping\|Masoudi, Hamid\|Leung, Samuel\|Wiseman, Sam M\|Nabi, Ivan R
PMID:	18922892

82.
Journal:	Hepatogastroenterology. 2008 Nov-Dec;55(88):2072-6.
Title:	Fibronectin promotes invasiveness and focal adhesion kinase tyrosine phosphorylation of human colon cancer cell.
Author:	Ding, Jian\|Li, Dan\|Wang, Xiaozhong\|Wang, Chengdang\|Wu, Ting
PMID:	19260479

83.
Journal:	BMC Cancer. 2009 Jan 12;9:12.
Title:	Paxillin-Y118 phosphorylation contributes to the control of Src-induced anchorage-independent growth by FAK and adhesion.
Author:	Sachdev, Sanjay\|Bu, Yahao\|Gelman, Irwin H
PMID:	19138410

84.
Journal:	Histol Histopathol. 2009 Apr;24(4):503-10.
Title:	Focal adhesion kinase and cancer.
Author:	Golubovskaya, Vita M\|Kweh, Frederick A\|Cance, William G
PMID:	19224453

85.
Journal:	Clin Exp Metastasis. 2009;26(5):447-56.
Title:	NK4, an HGF antagonist, prevents hematogenous pulmonary metastasis by inhibiting adhesion of CT26 cells to endothelial cells.
Author:	Kubota, Takeshi\|Taiyoh, Hiroaki\|Matsumura, Atsushi\|Murayama, Yasutoshi\|Ichikawa, Daisuke\|Okamoto, Kazuma\|Fujiwara, Hitoshi\|Ikoma, Hisashi\|Nakanishi, Masayoshi\|Kikuchi, Shojiro\|Sakakura, Chouhei\|Ochiai, Toshiya\|Kokuba, Yukihito\|Taniguchi, Hiroki\|Sonoyama,
PMID:	19234748

86.
Journal:	Cancer Res. 2009 Mar 15;69(6):2279-86.
Title:	Quantitative phosphoproteomics reveals a cluster of tyrosine kinases that mediates SRC invasive activity in advanced colon carcinoma cells.
Author:	Leroy, Cedric\|Fialin, Camille\|Sirvent, Audrey\|Simon, Valerie\|Urbach, Serge\|Poncet, Joel\|Robert, Bruno\|Jouin, Patrick\|Roche, Serge
PMID:	19276381

87.
Journal:	Lab Invest. 2009 Jun;89(6):717-25.
Title:	Inhibition of STAT5 induces G1 cell cycle arrest and reduces tumor cell invasion in human colorectal cancer cells.
Author:	Xiong, Hua\|Su, Wen-Yu\|Liang, Qin-Chuan\|Zhang, Zhi-Gang\|Chen, Hui-Min\|Du, Wan\|Chen, Ying-Xuan\|Fang, Jing-Yuan
PMID:	19290007

88.
Journal:	Cancer Sci. 2009 Sep;100(9):1708-13.
Title:	Knockdown of focal adhesion kinase reverses colon carcinoma multicellular resistance.
Author:	Chen, Yu-Ying\|Wang, Zhan-Xiang\|Chang, Ping-An\|Li, Jian-Jun\|Pan, Feng\|Yang, Li\|Bian, Zhi-Heng\|Zou, Lan\|He, Jian-Ming\|Liang, Hou-Jie
PMID:	19500106

89.
Journal:	Oncogene. 2009 Aug 27;28(34):3081-92.
Title:	XEDAR as a putative colorectal tumor suppressor that mediates p53-regulated anoikis pathway.
Author:	Tanikawa, C\|Furukawa, Y\|Yoshida, N\|Arakawa, H\|Nakamura, Y\|Matsuda, K
PMID:	19543321

90.
Journal:	Radiother Oncol. 2009 Sep;92(3):371-8.
Title:	3D cell cultures of human head and neck squamous cell carcinoma cells are radiosensitized by the focal adhesion kinase inhibitor TAE226.
Author:	Hehlgans, Stephanie\|Lange, Inga\|Eke, Iris\|Cordes, Nils
PMID:	19729215

91.
Journal:	Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2009 Sep;25(9):783-6.
Title:	[Effects of FAK expression level on proliferation and motility of colorectal carcinoma cells].
Author:	Pan, Ning\|Zhang, Ai-ran\|Mu, Mao-sen\|Hou, Ying-chun
PMID:	19737461

92.
Journal:	Transl Oncol. 2009 Dec;2(4):281-90.
Title:	Focal adhesion kinase functions as an akt downstream target in migration of colorectal cancer cells.
Author:	Tureckova, Jolana\|Vojtechova, Martina\|Krausova, Michaela\|Sloncova, Eva\|Korinek, Vladimir
PMID:	19956390

93.
Journal:	Int J Cancer. 2010 Jul 1;127(1):195-206.
Title:	The effect of focal adhesion kinase gene silencing on 5-fluorouracil chemosensitivity involves an Akt/NF-kappaB signaling pathway in colorectal carcinomas.
Author:	Chen, Yuying\|Wang, Zhanxiang\|Chang, Pingan\|Xiang, Liuxin\|Pan, Feng\|Li, Jianjun\|Jiang, Jinyan\|Zou, Lan\|Yang, Li\|Bian, Zhiheng\|Liang, Houjie
PMID:	19904749

94.
Journal:	Carcinogenesis. 2010 Apr;31(4):597-606.
Title:	TMPRSS4 induces invasion and epithelial-mesenchymal transition through upregulation of integrin alpha5 and its signaling pathways.
Author:	Kim, Semi\|Kang, Hee Young\|Nam, Eun-Hee\|Choi, Myung-Sook\|Zhao, Xue-Feng\|Hong, Chang Soo\|Lee, Jung Weon\|Lee, Jae Hyuk\|Park, Young-Kyu
PMID:	20118200

95.
Journal:	J Agric Food Chem. 2010 Mar 10;58(5):2935-42.
Title:	Benzyl isothiocyanate (BITC) inhibits migration and invasion of human colon cancer HT29 cells by inhibiting matrix metalloproteinase-2/-9 and urokinase plasminogen (uPA) through PKC and MAPK signaling pathway.
Author:	Lai, Kuang-Chi\|Huang, An-Cheng\|Hsu, Shu-Chun\|Kuo, Chao-Lin\|Yang, Jai-Sing\|Wu, Shin-Hwar\|Chung, Jing-Gung
PMID:	20136087

96.
Journal:	Thromb Res. 2010 Jun;125(6):e323-8.
Title:	Coagulation Factor Xa inhibits cancer cell migration via LIMK1-mediated cofilin inactivation.
Author:	Borensztajn, Keren\|Peppelenbosch, Maikel P\|Spek, C Arnold
PMID:	20347121

97.
Journal:	Front Biosci (Landmark Ed). 2010 Jun 1;15:901-12.
Title:	Focal adhesion kinase and p53 signal transduction pathways in cancer.
Author:	Golubovskaya, Vita M\|Cance, William
PMID:	20515733

98.
Journal:	Biochem Biophys Res Commun. 2010 Aug 27;399(3):434-9.
Title:	Integrin alpha8beta1 confers anoikis susceptibility to human intestinal epithelial crypt cells.
Author:	Benoit, Yannick D\|Larrivee, Jean-Francois\|Groulx, Jean-Francois\|Stankova, Jana\|Vachon, Pierre H\|Beaulieu, Jean-Francois
PMID:	20678483

99.
Journal:	Clin Cancer Res. 2010 Aug 15;16(16):4165-77.
Title:	Gene array and fluorescence in situ hybridization biomarkers of activity of saracatinib (AZD0530), a Src inhibitor, in a preclinical model of colorectal cancer.
Author:	Arcaroli, John J\|Touban, Basel M\|Tan, Aik Choon\|Varella-Garcia, Marileila\|Powell, Rebecca W\|Eckhardt, S Gail\|Elvin, Paul\|Gao, Dexiang\|Messersmith, Wells A
PMID:	20682712

100.
Journal:	Dev Cell. 2010 Aug 17;19(2):185-6.
Title:	Getting one's Fak straight.
Author:	Evan, Gerard
PMID:	20708578

101.
Journal:	Dev Cell. 2010 Aug 17;19(2):259-69.
Title:	Focal adhesion kinase is required for intestinal regeneration and tumorigenesis downstream of Wnt/c-Myc signaling.
Author:	Ashton, Gabrielle H\|Morton, Jennifer P\|Myant, Kevin\|Phesse, Toby J\|Ridgway, Rachel A\|Marsh, Victoria\|Wilkins, Julie A\|Athineos, Dimitris\|Muncan, Vanesa\|Kemp, Richard\|Neufeld, Kristi\|Clevers, Hans\|Brunton, Valerie\|Winton, Douglas J\|Wang, Xiaoyan\|Sears, Ros
PMID:	20708588

102.
Journal:	Int J Oncol. 2010 Oct;37(4):951-62.
Title:	P21-activated protein kinase 1 induces colorectal cancer metastasis involving ERK activation and phosphorylation of FAK at Ser-910.
Author:	Li, Liang-Hui\|Zheng, Min-Hua\|Luo, Qi\|Ye, Qing\|Feng, Bo\|Lu, Ai-Guo\|Wang, Ming-Liang\|Chen, Xue-Hua\|Su, Li-Ping\|Liu, Bing-Ya
PMID:	20811717

103.
Journal:	J Agric Food Chem. 2010 Oct 27;58(20):11148-55.
Title:	Phenethyl isothiocyanate inhibited tumor migration and invasion via suppressing multiple signal transduction pathways in human colon cancer HT29 cells.
Author:	Lai, Kuang-Chi\|Hsu, Shu-Chun\|Kuo, Chao-Lin\|Ip, Siu-Wan\|Yang, Jai-Sing\|Hsu, Yuan-Man\|Huang, Hui-Ying\|Wu, Shin-Hwar\|Chung, Jing-Gung
PMID:	20863062

104.
Journal:	PLoS One. 2010 Nov 30;5(11):e14143.
Title:	Molecular characterization of c-Abl/c-Src kinase inhibitors targeted against murine tumour progenitor cells that express stem cell markers.
Author:	Kruewel, Thomas\|Schenone, Silvia\|Radi, Marco\|Maga, Giovanni\|Rohrbeck, Astrid\|Botta, Maurizio\|Borlak, Juergen
PMID:	21152443

105.
Journal:	J Biomed Nanotechnol. 2010 Jun;6(3):272-8.
Title:	RNA interference-mediated silencing of focal adhesion kinase inhibits growth of human colon carcinoma xenograft in nude mice.
Author:	Lei, Ke\|Ye, Lu\|Yang, Yang\|Wang, Guan-Jie\|Jiang, Qing-Yuan\|Jiang, Yu\|Wei, Yu-Quan\|Deng, Hong-Xin
PMID:	21179944

106.
Journal:	Am J Physiol Cell Physiol. 2011 Mar;300(3):C657-70.
Title:	Akt directly regulates focal adhesion kinase through association and serine phosphorylation: implication for pressure-induced colon cancer metastasis.
Author:	Wang, Shouye\|Basson, Marc D
PMID:	21209368

107.
Journal:	Cancer Res. 2011 Jan 15;71(2):360-70.
Title:	p190RhoGEF (Rgnef) promotes colon carcinoma tumor progression via interaction with focal adhesion kinase.
Author:	Yu, Hong-Gang\|Nam, Ju-Ock\|Miller, Nichol L G\|Tanjoni, Isabelle\|Walsh, Colin\|Shi, Lei\|Kim, Linda\|Chen, Xiao Lei\|Tomar, Alok\|Lim, Ssang-Taek\|Schlaepfer, David D
PMID:	21224360

108.
Journal:	JOP. 2011 Mar 9;12(2):120-2.
Title:	Translational research in pancreatic cancer. Highlights from the "2011 ASCO Gastrointestinal Cancers Symposium". San Francisco, CA, USA. January 20-22, 2011.
Author:	Strimpakos, Alexios S\|Syrigos, Konstantinos N\|Saif, Muhammad Wasif
PMID:	21386635

109.
Journal:	Cancer Prev Res (Phila). 2011 Jul;4(7):1095-106.
Title:	Endocytosis of resveratrol via lipid rafts and activation of downstream signaling pathways in cancer cells.
Author:	Colin, Didier\|Limagne, Emeric\|Jeanningros, Sylvie\|Jacquel, Arnaud\|Lizard, Gerard\|Athias, Anne\|Gambert, Philippe\|Hichami, Aziz\|Latruffe, Norbert\|Solary, Eric\|Delmas, Dominique
PMID:	21467134

110.
Journal:	Oncogene. 2011 Sep 1;30(35):3766-83.
Title:	Type IV collagen-initiated signals provide survival and growth cues required for liver metastasis.
Author:	Burnier, J V\|Wang, N\|Michel, R P\|Hassanain, M\|Li, S\|Lu, Y\|Metrakos, P\|Antecka, E\|Burnier, M N\|Ponton, A\|Gallinger, S\|Brodt, P
PMID:	21478904

111.
Journal:	Anticancer Agents Med Chem. 2011 Sep;11(7):600-6.
Title:	FAK and WNT signaling: the meeting of two pathways in cancer and development.
Author:	Fonar, Yuri\|Frank, Dale
PMID:	21707509

112.
Journal:	J Biol Chem. 2011 Sep 9;286(36):31598-609.
Title:	ZF21 protein, a regulator of the disassembly of focal adhesions and cancer metastasis, contains a novel noncanonical pleckstrin homology domain.
Author:	Nagano, Makoto\|Hoshino, Daisuke\|Koshiba, Seizo\|Shuo, Takuya\|Koshikawa, Naohiko\|Tomizawa, Tadashi\|Hayashi, Fumiaki\|Tochio, Naoya\|Harada, Takushi\|Akizawa, Toshifumi\|Watanabe, Satoru\|Handa, Noriko\|Shirouzu, Mikako\|Kigawa, Takanori\|Yokoyama, Shigeyuki\|Seiki,
PMID:	21768110

113.
Journal:	Biol Cell. 2011 Nov;103(11):519-29.
Title:	alphav integrin processing interferes with the cross-talk between alphavbeta5/beta6 and alpha2beta1 integrins.
Author:	Defilles, Celine\|Montero, Marie-Pierre\|Lissitzky, Jean-Claude\|Rome, Sophie\|Siret, Carole\|Luis, Jose\|Andre, Frederic\|Rigot, Veronique
PMID:	21787362

114.
Journal:	Proteome Sci. 2011 Aug 17;9(1):49.
Title:	Resveratrol suppresses human colon cancer cell proliferation and induces apoptosis via targeting the pentose phosphate and the talin-FAK signaling pathways-A proteomic approach.
Author:	Vanamala, Jairam\|Radhakrishnan, Sridhar\|Reddivari, Lavanya\|Bhat, Vadiraja B\|Ptitsyn, Andrey
PMID:	21849056

115.
Journal:	Cancer Lett. 2011 Dec 27;313(2):167-80.
Title:	Lunasin potentiates the effect of oxaliplatin preventing outgrowth of colon cancer metastasis, binds to alpha5beta1 integrin and suppresses FAK/ERK/NF-kappaB signaling.
Author:	Dia, Vermont P\|Gonzalez de Mejia, Elvira
PMID:	21963225

116.
Journal:	Eur J Pharmacol. 2011 Dec 5;671(1-3):7-17.
Title:	Lysophosphatidic acid induces a migratory phenotype through a crosstalk between RhoA-Rock and Src-FAK signalling in colon cancer cells.
Author:	Leve, Fernanda\|Marcondes, Taline Guimaraes Correa\|Bastos, Lilian Goncalves R\|Rabello, Sarah Vieira\|Tanaka, Marcelo Neves\|Morgado-Diaz, Jose Andres
PMID:	21968138

117.
Journal:	J Biol Chem. 2011 Dec 9;286(49):42303-15.
Title:	Cellular settings mediating Src Substrate switching between focal adhesion kinase tyrosine 861 and CUB-domain-containing protein 1 (CDCP1) tyrosine 734.
Author:	Wortmann, Andreas\|He, Yaowu\|Christensen, Melinda E\|Linn, Mayla\|Lumley, John W\|Pollock, Pamela M\|Waterhouse, Nigel J\|Hooper, John D
PMID:	21994943

118.
Journal:	Nucleosides Nucleotides Nucleic Acids. 2011 Dec;30(12):1197-202.
Title:	Deoxyribose protects against rapamycin-induced cytotoxicity in colorectal cancer cells in vitro.
Author:	Bijnsdorp, I V\|Peters, G J
PMID:	22132975

119.
Journal:	Int J Cancer. 2012 Jul 15;131(2):298-309.
Title:	Recombinant canstatin inhibits angiopoietin-1-induced angiogenesis and lymphangiogenesis.
Author:	Hwang-Bo, Jeon\|Yoo, Ki Hyun\|Park, Jong-Hwa\|Jeong, Han-Sin\|Chung, In Sik
PMID:	21823121

120.
Journal:	Oncogene. 2012 Mar 29;31(13):1623-35.
Title:	MicroRNA-mediated upregulation of integrin-linked kinase promotes Src-induced tumor progression.
Author:	Oneyama, C\|Morii, E\|Okuzaki, D\|Takahashi, Y\|Ikeda, J\|Wakabayashi, N\|Akamatsu, H\|Tsujimoto, M\|Nishida, T\|Aozasa, K\|Okada, M
PMID:	21860426

121.
Journal:	Mol Cell Biochem. 2012 Feb;361(1-2):235-41.
Title:	Thrombin-dependent modulation of beta1-integrin-mediated signaling up-regulates prolidase and HIF-1alpha through p-FAK in colorectal cancer cells.
Author:	Karna, Ewa\|Szoka, Lukasz\|Palka, Jerzy
PMID:	21993963

122.
Journal:	Cancer Res. 2012 Mar 15;72(6):1504-17.
Title:	Inhibition of fatty acid synthase attenuates CD44-associated signaling and reduces metastasis in colorectal cancer.
Author:	Zaytseva, Yekaterina Y\|Rychahou, Piotr G\|Gulhati, Pat\|Elliott, Victoria A\|Mustain, William C\|O'Connor, Kathleen\|Morris, Andrew J\|Sunkara, Manjula\|Weiss, Heidi L\|Lee, Eun Y\|Evers, B Mark
PMID:	22266115

123.
Journal:	Mol Biosyst. 2012 Apr;8(4):1230-42.
Title:	Analysis of cell adhesion during early stages of colon cancer based on an extended multi-valued logic approach.
Author:	Guebel, Daniel V\|Schmitz, Ulf\|Wolkenhauer, Olaf\|Vera, Julio
PMID:	22298312

124.
Journal:	Carcinogenesis. 2012 May;33(5):1004-13.
Title:	A small molecule focal adhesion kinase (FAK) inhibitor, targeting Y397 site: 1-(2-hydroxyethyl)-3, 5, 7-triaza-1-azoniatricyclo [3.3.1.1(3,7)]decane; bromide effectively inhibits FAK autophosphorylation activity and decreases cancer cell viability, clonog
Author:	Golubovskaya, Vita M\|Figel, Sheila\|Ho, Baotran T\|Johnson, Christopher P\|Yemma, Michael\|Huang, Grace\|Zheng, Min\|Nyberg, Carl\|Magis, Andrew\|Ostrov, David A\|Gelman, Irwin H\|Cance, William G
PMID:	22402131

125.
Journal:	J Biol Chem. 2012 Aug 3;287(32):27126-38.
Title:	Down syndrome cell adhesion molecule (DSCAM) associates with uncoordinated-5C (UNC5C) in netrin-1-mediated growth cone collapse.
Author:	Purohit, Anish A\|Li, Weiquan\|Qu, Chao\|Dwyer, Trisha\|Shao, Qiangqiang\|Guan, Kun-Liang\|Liu, Guofa
PMID:	22685302

126.
Journal:	Biochem Biophys Res Commun. 2012 Jul 13;423(4):744-9.
Title:	Oral administration of FAK inhibitor TAE226 inhibits the progression of peritoneal dissemination of colorectal cancer.
Author:	Hao, Hui-fang\|Takaoka, Munenori\|Bao, Xiao-hong\|Wang, Zhi-gang\|Tomono, Yasuko\|Sakurama, Kazufumi\|Ohara, Toshiaki\|Fukazawa, Takuya\|Yamatsuji, Tomoki\|Fujiwara, Toshiyoshi\|Naomoto, Yoshio
PMID:	22705303

127.
Journal:	Korean J Pathol. 2012 Oct;46(5):454-62.
Title:	Expression of cortactin and focal adhesion kinase in colorectal adenocarcinoma: correlation with clinicopathologic parameters and their prognostic implication.
Author:	Kim, Yo Na\|Choi, Ji Eun\|Bae, Jun Sang\|Jang, Kyu Yun\|Chung, Myoung Ja\|Moon, Woo Sung\|Kang, Myoung Jae\|Lee, Dong Geun\|Park, Ho Sung
PMID:	23136572

128.
Journal:	Anticancer Agents Med Chem. 2013 May;13(4):532-45.
Title:	A small-molecule inhibitor, 5'-O-tritylthymidine, targets FAK and Mdm-2 interaction, and blocks breast and colon tumorigenesis in vivo.
Author:	Golubovskaya, Vita M\|Palma, Nadia L\|Zheng, Min\|Ho, Baotran\|Magis, Andrew\|Ostrov, David\|Cance, William G
PMID:	22292771

129.
Journal:	Oncogene. 2013 Apr 4;32(14):1863-8.
Title:	Lysyl oxidase enzymatic function increases stiffness to drive colorectal cancer progression through FAK.
Author:	Baker, A-M\|Bird, D\|Lang, G\|Cox, T R\|Erler, J T
PMID:	22641216

130.
Journal:	Int J Colorectal Dis. 2013 Jan;28(1):9-18.
Title:	FAK, CD44v6, c-Met and EGFR in colorectal cancer parameters: tumour progression, metastasis, patient survival and receptor crosstalk.
Author:	Garouniatis, Alexandros\|Zizi-Sermpetzoglou, Adamantia\|Rizos, Spyros\|Kostakis, Alkiviadis\|Nikiteas, Nikolaos\|Papavassiliou, Athanasios G
PMID:	22733437

131.
Journal:	Anticancer Agents Med Chem. 2013 May;13(4):584-94.
Title:	FAK and HAS inhibition synergistically decrease colon cancer cell viability and affect expression of critical genes.
Author:	Heffler, Melissa\|Golubovskaya, Vita M\|Conroy, Jeffrey\|Liu, Song\|Wang, Dan\|Cance, William G\|Dunn, Kelli B
PMID:	22934709

132.
Journal:	Oncogene. 2013 Sep 5;32(36):4304-12.
Title:	Protein tyrosine kinase 6 protects cells from anoikis by directly phosphorylating focal adhesion kinase and activating AKT.
Author:	Zheng, Y\|Gierut, J\|Wang, Z\|Miao, J\|Asara, J M\|Tyner, A L
PMID:	23027128

133.
Journal:	Int J Oncol. 2013 Feb;42(2):617-26.
Title:	Sphingosine kinase 1 promotes tumor progression and confers malignancy phenotypes of colon cancer by regulating the focal adhesion kinase pathway and adhesion molecules.
Author:	Liu, Shi-Quan\|Su, Ying-Jie\|Qin, Meng-Bin\|Mao, Ye-Bo\|Huang, Jie-An\|Tang, Guo-Du
PMID:	23232649

134.
Journal:	Cell Signal. 2013 Jan;25(1):66-73.
Title:	Rapid activation of FAK/mTOR/p70S6K/PAK1-signaling controls the early testosterone-induced actin reorganization in colon cancer cells.
Author:	Gu, Shuchen\|Kounenidakis, Michalis\|Schmidt, Eva-Maria\|Deshpande, Divija\|Alkahtani, Saad\|Alarifi, Saud\|Foller, Michael\|Alevizopoulos, Konstantinos\|Lang, Florian\|Stournaras, Christos
PMID:	23316499

135.
Journal:	Food Chem Toxicol. 2013 May;55:424-33.
Title:	Suppression of Src/ERK and GSK-3/beta-catenin signaling by pinosylvin inhibits the growth of human colorectal cancer cells.
Author:	Park, Eun-Jung\|Chung, Hwa-Jin\|Park, Hyen Joo\|Kim, Gi Dae\|Ahn, Yong-Hyun\|Lee, Sang Kook
PMID:	23333577

136.
Journal:	Int J Biochem Cell Biol. 2013 May;45(5):987-94.
Title:	Cell-surface GRP78 facilitates colorectal cancer cell migration and invasion.
Author:	Li, Zongwei\|Zhang, Lichao\|Zhao, Yarui\|Li, Hanqing\|Xiao, Hong\|Fu, Rong\|Zhao, Chao\|Wu, Haili\|Li, Zhuoyu
PMID:	23485528

137.
Journal:	Tumour Biol. 2013 Aug;34(4):2109-17.
Title:	Vascular endothelial growth factor receptors 1,3 and caveolin-1 are implicated in colorectal cancer aggressiveness and prognosis--correlations with epidermal growth factor receptor, CD44v6, focal adhesion kinase, and c-Met.
Author:	Garouniatis, Alexandros\|Zizi-Sermpetzoglou, Adamantia\|Rizos, Spyros\|Kostakis, Alkiviadis\|Nikiteas, Nikolaos\|Papavassiliou, Athanasios G
PMID:	23580180

138.
Journal:	BMC Cell Biol. 2013 May 25;14:25.
Title:	Syndecan-2 is upregulated in colorectal cancer cells through interactions with extracellular matrix produced by stromal fibroblasts.
Author:	Vicente, Carolina Meloni\|Ricci, Ritchelli\|Nader, Helena Bonciani\|Toma, Leny
PMID:	23705906

139.
Journal:	Cancer Biol Ther. 2013 Aug;14(8):761-72.
Title:	Focal adhesion kinase autophosphorylation inhibition decreases colon cancer cell growth and enhances the efficacy of chemotherapy.
Author:	Heffler, Melissa\|Golubovskaya, Vita M\|Dunn, Kelli M Bullard\|Cance, William
PMID:	23792569

140.
Journal:	Stem Cell Res. 2013 Sep;11(2):820-33.
Title:	Fibronectin extra domain A (EDA) sustains CD133(+)/CD44(+) subpopulation of colorectal cancer cells.
Author:	Ou, Juanjuan\|Deng, Jia\|Wei, Xing\|Xie, Ganfeng\|Zhou, Rongbin\|Yu, Liqing\|Liang, Houjie
PMID:	23811539

141.
Journal:	Radiother Oncol. 2013 Jul;108(1):32-9.
Title:	Double targeting of Survivin and XIAP radiosensitizes 3D grown human colorectal tumor cells and decreases migration.
Author:	Hehlgans, Stephanie\|Petraki, Chrysi\|Reichert, Sebastian\|Cordes, Nils\|Rodel, Claus\|Rodel, Franz
PMID:	23830189

142.
Journal:	Biochim Biophys Acta. 2013 Nov;1834(11):2293-307.
Title:	Sulindac modulates secreted protein expression from LIM1215 colon carcinoma cells prior to apoptosis.
Author:	Greening, David W\|Ji, Hong\|Kapp, Eugene A\|Simpson, Richard J
PMID:	23899461

143.
Journal:	Evid Based Complement Alternat Med. 2013;2013:541695.
Title:	Curcumin Suppresses Metastasis via Sp-1, FAK Inhibition, and E-Cadherin Upregulation in Colorectal Cancer.
Author:	Chen, Chun-Chieh\|Sureshbabul, Munisamy\|Chen, Huei-Wen\|Lin, Yu-Shuang\|Lee, Jen-Yi\|Hong, Qi-Sheng\|Yang, Ya-Chien\|Yu, Sung-Liang
PMID:	23970932

144.
Journal:	Zhonghua Zhong Liu Za Zhi. 2013 May;35(5):331-6.
Title:	[Sphingosine kinase 1 enhances the proliferation and invasion of human colon cancer LoVo cells through up-regulating FAK pathway and the expression of ICAM-1 and VCAM-1].
Author:	Liu, Shi-quan\|Su, Ying-jie\|Huang, Jie-an\|Qin, Meng-bin\|Tang, Guo-du
PMID:	24054007

145.
Journal:	PLoS One. 2013 Nov 27;8(11):e81592.
Title:	Anti-cancer activity of an osthole derivative, NBM-T-BMX-OS01: targeting vascular endothelial growth factor receptor signaling and angiogenesis.
Author:	Yang, Hung-Yu\|Hsu, Ya-Fen\|Chiu, Pei-Ting\|Ho, Shiau-Jing\|Wang, Chi-Han\|Chi, Chih-Chin\|Huang, Yu-Han\|Lee, Cheng-Feng\|Li, Ying-Shiuan\|Ou, George\|Hsu, Ming-Jen
PMID:	24312323

146.
Journal:	Mol Carcinog. 2014 Feb;53 Suppl 1:E62-71.
Title:	The molecular chaperone Cosmc enhances malignant behaviors of colon cancer cells via activation of Akt and ERK.
Author:	Huang, John\|Che, Mei-Ieng\|Lin, Neng-Yu\|Hung, Ji-Shiang\|Huang, Yu-Ting\|Lin, Wei-Chou\|Huang, Hsiu-Chin\|Lee, Po-Huang\|Liang, Jin-Tung\|Huang, Min-Chuan
PMID:	23390052

147.
Journal:	Dig Dis Sci. 2014 May;59(5):958-67.
Title:	Dysregulation of microRNA-34a expression in colorectal cancer inhibits the phosphorylation of FAK via VEGF.
Author:	Zhang, Danhua\|Zhou, Jianping\|Dong, Ming
PMID:	24370784

148.
Journal:	Cancers (Basel). 2014 Jan 21;6(1):166-78.
Title:	Gene Expression Profiling Identifies Important Genes Affected by R2 Compound Disrupting FAK and P53 Complex.
Author:	Golubovskaya, Vita M\|Ho, Baotran\|Conroy, Jeffrey\|Liu, Song\|Wang, Dan\|Cance, William G
PMID:	24452144

149.
Journal:	Int J Med Sci. 2014 Jan 21;11(3):268-75.
Title:	Role of overexpression of MACC1 and/or FAK in predicting prognosis of hepatocellular carcinoma after liver transplantation.
Author:	Gao, Sheng\|Lin, Bing-Yi\|Yang, Zhe\|Zheng, Zhi-Yun\|Liu, Zhi-Kun\|Wu, Li-Ming\|Xie, Hai-Yang\|Zhou, Lin\|Zheng, Shu-Sen
PMID:	24516351

150.
Journal:	Asian Pac J Cancer Prev. 2014;15(7):3045-50.
Title:	Targeting EGFL7 expression through RNA interference suppresses renal cell carcinoma growth by inhibiting angiogenesis.
Author:	Xu, Han-Feng\|Chen, Lei\|Liu, Xian-Dong\|Zhan, Yun-Hong\|Zhang, Hui-Hui\|Li, Qing\|Wu, Bin
PMID:	24815445

151.
Journal:	Biochim Biophys Acta. 2014 Sep;1843(9):2129-37.
Title:	Radiation sensitization of tumor cells induced by shear stress: the roles of integrins and FAK.
Author:	Luo, Chi-Wen\|Wu, Chia-Ching\|Ch'ang, Hui-Ju
PMID:	24946134

152.
Journal:	Pathol Res Pract. 2014 Oct;210(10):668-74.
Title:	Association of CD98, integrin beta1, integrin beta3 and Fak with the progression and liver metastases of colorectal cancer.
Author:	Sun, Cuicui\|Zargham, Ramin\|Shao, Qin\|Gui, Xianyong\|Marcus, Victoria\|Lazaris, Anthoula\|Salman, Ayat\|Metrakos, Peter\|Qu, Xianjun\|Gao, Zuhua
PMID:	25041835

153.
Journal:	Anticancer Res. 2014 Aug;34(8):3969-74.
Title:	Nuclear expression of phosphorylated focal adhesion kinase is associated with poor prognosis in human colorectal cancer.
Author:	Albasri, Abdulkader\|Fadhil, Wakkas\|Scholefield, John H\|Durrant, Lindy G\|Ilyas, Mohammad
PMID:	25075018

154.
Journal:	Toxicol Appl Pharmacol. 2014 Dec 1;281(2):166-73.
Title:	Dioscin inhibits colon tumor growth and tumor angiogenesis through regulating VEGFR2 and AKT/MAPK signaling pathways.
Author:	Tong, Qingyi\|Qing, Yong\|Wu, Yang\|Hu, Xiaojuan\|Jiang, Lei\|Wu, Xiaohua
PMID:	25111127

155.
Journal:	Apoptosis. 2014 Oct;19(10):1532-44.
Title:	Urokinase-type plasminogen activator receptor regulates apoptotic sensitivity of colon cancer HCT116 cell line to TRAIL via JNK-p53 pathway.
Author:	Liu, Xiufeng\|Qiu, Fan\|Liu, Zhipeng\|Lan, Yan\|Wang, Kai\|Zhou, Ping-Kun\|Wang, Yao\|Hua, Zi-Chun
PMID:	25113506

156.
Journal:	Front Physiol. 2014 Aug 8;5:293.
Title:	NFAT5-mediated expression of S100A4 contributes to proliferation and migration of renal carcinoma cells.
Author:	Kuper, Christoph\|Beck, Franz-Xaver\|Neuhofer, Wolfgang
PMID:	25152734

157.
Journal:	BMC Cancer. 2014 Aug 30;14:639.
Title:	Heat shock proteins HSP70 and MRJ cooperatively regulate cell adhesion and migration through urokinase receptor.
Author:	Lin, Yuli\|Peng, Nana\|Zhuang, Hongqin\|Zhang, Di\|Wang, Yao\|Hua, Zi-Chun
PMID:	25175595

158.
Journal:	BMC Cancer. 2014 Sep 10;14:660.
Title:	Src activity is modulated by oxaliplatin and correlates with outcomes after hepatectomy for metastatic colorectal cancer.
Author:	Kopetz, Scott\|Morris, Van K\|Parikh, Nila\|Overman, Michael J\|Jiang, Zhi-Qin\|Maru, Dipen\|Elvin, Paul\|Gallick, Gary
PMID:	25208577

159.
Journal:	Environ Toxicol. 2015 Jul;30(7):852-63.
Title:	Crude extract of Rheum palmatum L inhibits migration and invasion of LS1034 human colon cancer cells acts through the inhibition of matrix metalloproteinase-2/-9 by MAPK signaling.
Author:	Ma, Yi-Shih\|Hsiao, Yu-Ping\|Lin, Ju-Hwa\|Hsu, Shu-Chun\|Chueh, Fu-Shin\|Weng, Shu-Wen\|Lai, Kuang-Chi\|Lin, Jaung-Geng\|Chung, Jing-Gung
PMID:	24497447

160.
Journal:	Oncogene. 2015 Jun 11;34(24):3120-30.
Title:	Progastrin a new pro-angiogenic factor in colorectal cancer.
Author:	Najib, S\|Kowalski-Chauvel, A\|Do, C\|Roche, S\|Cohen-Jonathan-Moyal, E\|Seva, C
PMID:	25109333

161.
Journal:	J Cell Mol Med. 2015 Feb;19(2):383-95.
Title:	A novel synthetic small molecule YH-306 suppresses colorectal tumour growth and metastasis via FAK pathway.
Author:	Dai, Fujun\|Chen, Yihua\|Huang, Li\|Wang, Jinhua\|Zhang, Tao\|Li, Jingjie\|Tong, Weiguang\|Liu, Mingyao\|Yi, Zhengfang
PMID:	25351103

162.
Journal:	J Cell Mol Med. 2015 Feb;19(2):474-84.
Title:	Diallyl trisulfide inhibits migration, invasion and angiogenesis of human colon cancer HT-29 cells and umbilical vein endothelial cells, and suppresses murine xenograft tumour growth.
Author:	Lai, Kuang-Chi\|Hsu, Shu-Chun\|Yang, Jai-Sing\|Yu, Chien-Chih\|Lein, Jin-Cherng\|Chung, Jing-Gung
PMID:	25403643

163.
Journal:	Cancer Lett. 2015 Mar 28;358(2):200-209.
Title:	Neuropilin-2 mediates lymphangiogenesis of colorectal carcinoma via a VEGFC/VEGFR3 independent signaling.
Author:	Ou, Juan-Juan\|Wei, Xing\|Peng, Yuan\|Zha, Lin\|Zhou, Rong-Bin\|Shi, Hang\|Zhou, Qi\|Liang, Hou-Jie
PMID:	25543087

164.
Journal:	Elife. 2015 Jan 26;4:e04069.
Title:	Defective apical extrusion signaling contributes to aggressive tumor hallmarks.
Author:	Gu, Yapeng\|Shea, Jill\|Slattum, Gloria\|Firpo, Matthew A\|Alexander, Margaret\|Mulvihill, Sean J\|Golubovskaya, Vita M\|Rosenblatt, Jody
PMID:	25621765

165.
Journal:	PLoS One. 2015 Jan 28;10(1):e0116984.
Title:	Modulation of intracellular calcium levels by calcium lactate affects colon cancer cell motility through calcium-dependent calpain.
Author:	Sundaramoorthy, Pasupathi\|Sim, Jae Jun\|Jang, Yeong-Su\|Mishra, Siddhartha Kumar\|Jeong, Keun-Yeong\|Mander, Poonam\|Chul, Oh Byung\|Shim, Won-Sik\|Oh, Seung Hyun\|Nam, Ky-Youb\|Kim, Hwan Mook
PMID:	25629974

166.
Journal:	Phytomedicine. 2015 Jan 15;22(1):103-10.
Title:	Raddeanin A, a triterpenoid saponin isolated from Anemone raddeana, suppresses the angiogenesis and growth of human colorectal tumor by inhibiting VEGFR2 signaling.
Author:	Guan, Ying-Yun\|Liu, Hai-Jun\|Luan, Xin\|Xu, Jian-Rong\|Lu, Qin\|Liu, Ya-Rong\|Gao, Yun-Ge\|Zhao, Mei\|Chen, Hong-Zhuan\|Fang, Chao
PMID:	25636878

167.
Journal:	Phytother Res. 2015 May;29(5):714-23.
Title:	Corosolic Acid Exhibits Anti-angiogenic and Anti-lymphangiogenic Effects on In Vitro Endothelial Cells and on an In Vivo CT-26 Colon Carcinoma Animal Model.
Author:	Yoo, Ki Hyun\|Park, Jong-Hwa\|Lee, Dae Young\|Hwang-Bo, Jeon\|Baek, Nam In\|Chung, In Sik
PMID:	25644809

168.
Journal:	J Cancer Res Clin Oncol. 2015 Sep;141(9):1613-31.
Title:	Down-regulation of ALDH1A3, CD44 or MDR1 sensitizes resistant cancer cells to FAK autophosphorylation inhibitor Y15.
Author:	Golubovskaya, Vita\|O'Brien, Shalana\|Ho, Baotran\|Heffler, Melissa\|Conroy, Jeffrey\|Hu, Quang\|Wang, Dan\|Liu, Song\|Cance, William G
PMID:	25656374

169.
Journal:	Med Oncol. 2015 Apr;32(4):125.
Title:	The effects of focal adhesion kinase on the motility, proliferation and apoptosis of Caco2 and SMMC-7721 cells.
Author:	Gao, Ning\|He, Huimin\|Xiao, Li\|Gao, Xiaojie\|Shi, Hongyan\|Wu, Qiong\|Xu, Nan\|Lei, Yuqing\|Song, Xigui\|Hou, Yingchun
PMID:	25790781

170.
Journal:	Int J Biochem Cell Biol. 2015 Jul;64:45-57.
Title:	Human enhancer of filamentation 1-induced colorectal cancer cell migration: Role of serine phosphorylation and interaction with the breast cancer anti-estrogen resistance 3 protein.
Author:	Ibrahim, Rama\|Lemoine, Antoinette\|Bertoglio, Jacques\|Raingeaud, Joel
PMID:	25817040

171.
Journal:	Int J Oncol. 2015;46(6):2621-8.
Title:	Inhibitory effects of proton beam irradiation on integrin expression and signaling pathway in human colon carcinoma HT29 cells.
Author:	Ha, Byung Geun\|Park, Jung-Eun\|Cho, Hyun-Jung\|Lim, Young-Bin\|Shon, Yun Hee
PMID:	25845382

172.
Journal:	J Cell Biochem. 2015 Oct;116(10):2385-96.
Title:	Colorectal Cancer Metastases Settle in the Hepatic Microenvironment Through alpha5beta1 Integrin.
Author:	Pelillo, Chiara\|Bergamo, Alberta\|Mollica, Hilaria\|Bestagno, Marco\|Sava, Gianni
PMID:	25857463

173.
Journal:	Cancer Res. 2015 Jun 15;75(12):2434-44.
Title:	IL13 Receptor alpha2 Signaling Requires a Scaffold Protein, FAM120A, to Activate the FAK and PI3K Pathways in Colon Cancer Metastasis.
Author:	Bartolome, Ruben A\|Garcia-Palmero, Irene\|Torres, Sofia\|Lopez-Lucendo, Maria\|Balyasnikova, Irina V\|Casal, J Ignacio
PMID:	25896327

174.
Journal:	J Biol Chem. 2015 Jun 12;290(24):15197-209.
Title:	Gastrin-stimulated Galpha13 Activation of Rgnef Protein (ArhGEF28) in DLD-1 Colon Carcinoma Cells.
Author:	Masia-Balague, Miriam\|Izquierdo, Ismael\|Garrido, Georgina\|Cordomi, Arnau\|Perez-Benito, Laura\|Miller, Nichol L G\|Schlaepfer, David D\|Gigoux, Veronique\|Aragay, Anna M
PMID:	25922072

175.
Journal:	Int J Biochem Cell Biol. 2015 Jul;64:202-11.
Title:	Overexpressed GRP78 affects EMT and cell-matrix adhesion via autocrine TGF-beta/Smad2/3 signaling.
Author:	Zhang, Lichao\|Li, Zongwei\|Fan, Yongsheng\|Li, Hanqing\|Li, Zhouyu\|Li, Yaoping
PMID:	25934251

176.
Journal:	Oncol Rep. 2015 Sep;34(3):1178-84.
Title:	Widdrol, a sesquiterpene isolated from Juniperus chinensis, inhibits angiogenesis by targeting vascular endothelial growth factor receptor 2 signaling.
Author:	Jin, Soojung\|Yun, Hee Jung\|Jeong, Hyun Young\|Oh, You Na\|Park, Hyun-Jin\|Yun, Seung-Geun\|Kim, Byung Woo\|Kwon, Hyun Ju
PMID:	26133679

177.
Journal:	Elife. 2015 Sep 3;4.
Title:	FAK/PYK2 promotes the Wnt/beta-catenin pathway and intestinal tumorigenesis by phosphorylating GSK3beta.
Author:	Gao, Chenxi\|Chen, Guangming\|Kuan, Shih-Fan\|Zhang, Dennis Han\|Schlaepfer, David D\|Hu, Jing
PMID:	26274564

178.
Journal:	Clin Cancer Drugs. 2015 Feb;2(2):100-111.
Title:	Emerging Role and Targeting of Carcinoembryonic Antigen-related Cell Adhesion Molecule 6 (CEACAM6) in Human Malignancies.
Author:	Johnson, Benny\|Mahadevan, Daruka
PMID:	27595061

179.
Journal:	Cell Death Differ. 2016 Apr;23(4):707-22.
Title:	DNA damage-induced ephrin-B2 reverse signaling promotes chemoresistance and drives EMT in colorectal carcinoma harboring mutant p53.
Author:	Alam, S K\|Yadav, V K\|Bajaj, S\|Datta, A\|Dutta, S K\|Bhattacharyya, M\|Bhattacharya, S\|Debnath, S\|Roy, S\|Boardman, L A\|Smyrk, T C\|Molina, J R\|Chakrabarti, S\|Chowdhury, S\|Mukhopadhyay, D\|Roychoudhury, S
PMID:	26494468

180.
Journal:	Mol Med Rep. 2016 Feb;13(2):1297-303.
Title:	MicroRNA7 suppresses human colon cancer invasion and proliferation by targeting the expression of focal adhesion kinase.
Author:	Zeng, Chun-Yan\|Zhan, Yi-Shan\|Huang, Jun\|Chen, You-Xiang
PMID:	26648422

181.
Journal:	Int J Oncol. 2016 Apr;48(4):1553-60.
Title:	Suppression of lysyl-tRNA synthetase, KRS, causes incomplete epithelial-mesenchymal transition and ineffective cellextracellular matrix adhesion for migration.
Author:	Nam, Seo Hee\|Kang, Minkyung\|Ryu, Jihye\|Kim, Hye-Jin\|Kim, Doyeun\|Kim, Dae Gyu\|Kwon, Nam Hoon\|Kim, Sunghoon\|Lee, Jung Weon
PMID:	26891990

182.
Journal:	Mol Pharmacol. 2016 May;89(5):521-40.
Title:	Targeting the Metastasis Suppressor, N-Myc Downstream Regulated Gene-1, with Novel Di-2-Pyridylketone Thiosemicarbazones: Suppression of Tumor Cell Migration and Cell-Collagen Adhesion by Inhibiting Focal Adhesion Kinase/Paxillin Signaling.
Author:	Wangpu, Xiongzhi\|Lu, Jiaoyang\|Xi, Ruxing\|Yue, Fei\|Sahni, Sumit\|Park, Kyung Chan\|Menezes, Sharleen\|Huang, Michael L H\|Zheng, Minhua\|Kovacevic, Zaklina\|Richardson, Des R
PMID:	26895766

183.
Journal:	J Inorg Biochem. 2016 Jul;160:225-35.
Title:	Inhibition of adhesion, migration and of alpha5beta1 integrin in the HCT-116 colorectal cancer cells treated with the ruthenium drug NAMI-A.
Author:	Pelillo, Chiara\|Mollica, Hilaria\|Eble, Johannes A\|Grosche, Julius\|Herzog, Lea\|Codan, Barbara\|Sava, Gianni\|Bergamo, Alberta
PMID:	26961176

184.
Journal:	Cancer Chemother Pharmacol. 2016 May;77(5):997-1003.
Title:	A first-in-Asian phase 1 study to evaluate safety, pharmacokinetics and clinical activity of VS-6063, a focal adhesion kinase (FAK) inhibitor in Japanese patients with advanced solid tumors.
Author:	Shimizu, Toshio\|Fukuoka, Kazuya\|Takeda, Masayuki\|Iwasa, Tutomu\|Yoshida, Takeshi\|Horobin, Joanna\|Keegan, Mitchell\|Vaickus, Lou\|Chavan, Ajit\|Padval, Mahesh\|Nakagawa, Kazuhiko
PMID:	27025608

185.
Journal:	J Hum Genet. 2016 Aug;61(8):711-20.
Title:	Claudin-7 indirectly regulates the integrin/FAK signaling pathway in human colon cancer tissue.
Author:	Ding, Lei\|Wang, Liyong\|Sui, Leiming\|Zhao, Huanying\|Xu, Xiaoxue\|Li, Tengyan\|Wang, Xiaonan\|Li, Wenjing\|Zhou, Ping\|Kong, Lu
PMID:	27121327

186.
Journal:	Oncotarget. 2016 May 17;7(20):29592-604.
Title:	Ninjurin1 inhibits colitis-mediated colon cancer development and growth by suppression of macrophage infiltration through repression of FAK signaling.
Author:	Woo, Jong Kyu\|Jang, Yeong-Su\|Kang, Ju-Hee\|Hwang, Jong-Ik\|Seong, Je Kyung\|Lee, Sang-Jin\|Jeon, Sejin\|Oh, Goo Taeg\|Lee, Ho-Young\|Oh, Seung Hyun
PMID:	27127177

187.
Journal:	J Cell Mol Med. 2016 Sep;20(9):1729-36.
Title:	Focal adhesion kinase: predictor of tumour response and risk factor for recurrence after neoadjuvant chemoradiation in rectal cancer.
Author:	Gomez Del Pulgar, Teresa\|Cebrian, Arancha\|Fernandez-Acenero, Maria Jesus\|Borrero-Palacios, Aurea\|Del Puerto-Nevado, Laura\|Martinez-Useros, Javier\|Marin-Arango, Juan Pablo\|Carames, Cristina\|Vega-Bravo, Ricardo\|Rodriguez-Remirez, Maria\|Cruz-Ramos, Marlid\|Ma
PMID:	27171907

188.
Journal:	FEBS Lett. 2016 Jun;590(12):1826-37.
Title:	Activation of focal adhesion kinase through an interaction with beta4 integrin contributes to tumorigenicity of colon cancer.
Author:	Tai, Yu-Ling\|Lai, I-Rue\|Peng, Yu-Ju\|Ding, Shih-Torng\|Shen, Tang-Long
PMID:	27178753

189.
Journal:	Bioorg Med Chem Lett. 2016 Aug 15;26(16):3963-7.
Title:	Timosaponin AIII inhibits migration and invasion of A549 human non-small-cell lung cancer cells via attenuations of MMP-2 and MMP-9 by inhibitions of ERK1/2, Src/FAK and beta-catenin signaling pathways.
Author:	Jung, Okkeun\|Lee, Jongsung\|Lee, Yu Jin\|Yun, Jung-Mi\|Son, Young-Jin\|Cho, Jae Youl\|Ryou, Chongsuk\|Lee, Sang Yeol
PMID:	27422337

190.
Journal:	Tumour Biol. 2016 Oct;37(10):13355-13368.
Title:	Neutral endopeptidase (NEP) is differentially involved in biological activities and cell signaling of colon cancer cell lines derived from various stages of tumor development.
Author:	Mizerska-Kowalska, Magdalena\|Bojarska-Junak, Agnieszka\|Jakubowicz-Gil, Joanna\|Kandefer-Szerszen, Martyna
PMID:	27460083

191.
Journal:	Oncotarget. 2016 Sep 27;7(39):63124-63137.
Title:	DDA suppresses angiogenesis and tumor growth of colorectal cancer in vivo through decreasing VEGFR2 signaling.
Author:	Huang, Shiu-Wen\|Lien, Jin-Cherng\|Kuo, Sheng-Chu\|Huang, Tur-Fu
PMID:	27517319

192.
Journal:	J Exp Clin Cancer Res. 2016 Sep 20;35(1):148.
Title:	TIMP1 is a prognostic marker for the progression and metastasis of colon cancer through FAK-PI3K/AKT and MAPK pathway.
Author:	Song, Guohe\|Xu, Shifeng\|Zhang, Hong\|Wang, Yupeng\|Xiao, Chao\|Jiang, Tao\|Wu, Leilei\|Zhang, Tao\|Sun, Xing\|Zhong, Lin\|Zhou, Chongzhi\|Wang, Zhaowen\|Peng, Zhihai\|Chen, Jian\|Wang, Xiaoliang
PMID:	27644693

193.
Journal:	Toxicol Appl Pharmacol. 2016 Nov 15;311:106-112.
Title:	Downregulation of NEDD9 by apigenin suppresses migration, invasion, and metastasis of colorectal cancer cells.
Author:	Dai, Jin\|Van Wie, Peter G\|Fai, Leonard Yenwong\|Kim, Donghern\|Wang, Lei\|Poyil, Pratheeshkumar\|Luo, Jia\|Zhang, Zhuo
PMID:	27664007

194.
Journal:	Int J Mol Sci. 2016 Nov 8;17(11). pii: ijms17111860.
Title:	Focal Adhesion Kinase-Dependent Role of the Soluble Form of Neurotensin Receptor-3/Sortilin in Colorectal Cancer Cell Dissociation.
Author:	Beraud-Dufour, Sophie\|Devader, Chistelle\|Massa, Fabienne\|Roulot, Morgane\|Coppola, Thierry\|Mazella, Jean
PMID:	27834811

195.
Journal:	Onco Targets Ther. 2016 Nov 30;9:7285-7295.
Title:	CTGF enhances resistance to 5-FU-mediating cell apoptosis through FAK/MEK/ERK signal pathway in colorectal cancer.
Author:	Yang, Kai\|Gao, Kai\|Hu, Gui\|Wen, Yanguang\|Lin, Changwei\|Li, Xiaorong
PMID:	27942222

196.
Journal:	Clin Cancer Res. 2017 Jan 1;23(1):159-170.
Title:	Dysregulation of EGFR Pathway in EphA2 Cell Subpopulation Significantly Associates with Poor Prognosis in Colorectal Cancer.
Author:	De Robertis, Mariangela\|Loiacono, Luisa\|Fusilli, Caterina\|Poeta, Maria Luana\|Mazza, Tommaso\|Sanchez, Massimo\|Marchionni, Luigi\|Signori, Emanuela\|Lamorte, Giuseppe\|Vescovi, Angelo Luigi\|Garcia-Foncillas, Jesus\|Fazio, Vito Michele
PMID:	27401248

197.
Journal:	Anticancer Res. 2017 Jan;37(1):103-114.
Title:	Synergistically Anti-metastatic Effect of 5-Flourouracil on Colorectal Cancer Cells via Calcium-mediated Focal Adhesion Kinase Proteolysis.
Author:	Park, Minhee\|Sundaramoorthy, Pasupathi\|Sim, Jae Jun\|Jeong, Keun-Yeong\|Kim, Hwan Mook
PMID:	28011480

198.
Journal:	Mol Med Rep. 2017 Mar;15(3):1222-1228.
Title:	Effect of ART1 on the proliferation and migration of mouse colon carcinoma CT26 cells in vivo.
Author:	Xu, Jian-Xia\|Xiong, Wei\|Zeng, Zhen\|Tang, Yi\|Wang, Ya-Lan\|Xiao, Ming\|Li, Ming\|Li, Qing Shu\|Song, Guang-Lin\|Kuang, Jing
PMID:	28138708

199.
Journal:	Oncotarget. 2017 Apr 4;8(14):22674-22684.
Title:	MicroRNA-146a promote cell migration and invasion in human colorectal cancer via carboxypeptidase M/src-FAK pathway.
Author:	Lu, Di\|Yao, Qunyan\|Zhan, Cheng\|Le-Meng, Zhang\|Liu, Hongchun\|Cai, Yu\|Tu, Chuantao\|Li, Xi\|Zou, Yanting\|Zhang, Shuncai
PMID:	28186967

200.
Journal:	Theranostics. 2017 Jan 11;7(3):594-613.
Title:	Anti-cancer Activity of Novel TM4SF5-Targeting Antibodies through TM4SF5 Neutralization and Immune Cell-Mediated Cytotoxicity.
Author:	Ahn, Hye-Mi\|Ryu, Jihye\|Song, Jin Myeong\|Lee, Yunhee\|Kim, Hye-Jin\|Ko, Dongjoon\|Choi, Inpyo\|Kim, Sang Jick\|Lee, Jung Weon\|Kim, Semi
PMID:	28255353

201.
Journal:	Clin Cancer Res. 2017 Aug 1;23(15):4146-4154.
Title:	Dual Inhibition of EGFR and c-Src by Cetuximab and Dasatinib Combined with FOLFOX Chemotherapy in Patients with Metastatic Colorectal Cancer.
Author:	Parseghian, Christine M\|Parikh, Nila U\|Wu, Ji Yuan\|Jiang, Zhi-Qin\|Henderson, Laura\|Tian, Feng\|Pastor, Brice\|Ychou, Marc\|Raghav, Kanwal\|Dasari, Arvind\|Fogelman, David R\|Katsiampoura, Anastasia D\|Menter, David G\|Wolff, Robert A\|Eng, Cathy\|Overman, Michael J
PMID:	28280091

202.
Journal:	J Mol Endocrinol. 2017 Jul;59(1):13-27.
Title:	RSK activation via ERK modulates human colon cancer cells response to PTHrP.
Author:	Calvo, Natalia\|Carriere, Pedro\|Martin, Maria Julia\|Gentili, Claudia
PMID:	28385776

203.
Journal:	Int J Mol Med. 2017 May;39(5):1277-1284.
Title:	SphK1 modulates cell migration and EMT-related marker expression by regulating the expression of p-FAK in colorectal cancer cells.
Author:	Xu, Chun-Yan\|Liu, Shi-Quan\|Qin, Meng-Bin\|Zhuge, Chun-Feng\|Qin, Lin\|Qin, Nan\|Lai, Ming-Yu\|Huang, Jie-An
PMID:	28405684

204.
Journal:	Mol Carcinog. 2017 Sep;56(9):2066-2075.
Title:	The nuclear orphan receptor NR4A1 regulates beta1-integrin expression in pancreatic and colon cancer cells and can be targeted by NR4A1 antagonists.
Author:	Hedrick, Erik\|Lee, Syng-Ook\|Safe, Stephen
PMID:	28418095

205.
Journal:	Biochim Biophys Acta Mol Cell Res. 2017 Jul;1864(7):1246-1259.
Title:	A crosstalk between muscarinic and CRF2 receptors regulates cellular adhesion properties of human colon cancer cells.
Author:	Pelissier-Rota, M\|Chartier, N T\|Bonaz, B\|Jacquier-Sarlin, M R
PMID:	28432022

206.
Journal:	Anticancer Res. 2017 Jun;37(6):2959-2964.
Title:	Enhancing 5-Fluorouracil Efficacy in a Primary Colorectal Cancer by Long-lasting Calcium Supplementation.
Author:	Jeong, Keun-Yeong\|Park, Minhee\|Kim, In Un\|Sim, Jae Jun\|Kim, Hwan Mook
PMID:	28551633

207.
Journal:	PLoS One. 2017 May 31;12(5):e0178515.
Title:	The four-transmembrane protein MAL2 and tumor protein D52 (TPD52) are highly expressed in colorectal cancer and correlated with poor prognosis.
Author:	Li, Jingwen\|Li, Yongmin\|Liu, He\|Liu, Yanlong\|Cui, Binbin
PMID:	28562687

208.
Journal:	Oncotarget. 2017 Jul 18;8(29):47931-47942.
Title:	TRIB1 promotes colorectal cancer cell migration and invasion through activation MMP-2 via FAK/Src and ERK pathways.
Author:	Wang, Yuhui\|Wu, Nan\|Pang, Bo\|Tong, Dandan\|Sun, Donglin\|Sun, Haiming\|Zhang, Chunyu\|Sun, Wenjing\|Meng, Xiangning\|Bai, Jing\|Chen, Feng\|Geng, Jingshu\|Fu, Songbin\|Jin, Yan
PMID:	28624785

209.
Journal:	Oncogene. 2017 Nov 2;36(44):6132-6142.
Title:	Cellular prion protein (PrP(C)) in the development of Merlin-deficient tumours.
Author:	Provenzano, L\|Ryan, Y\|Hilton, D A\|Lyons-Rimmer, J\|Dave, F\|Maze, E A\|Adams, C L\|Rigby-Jones, R\|Ammoun, S\|Hanemann, C O
PMID:	28692055

210.
Journal:	Mol Biol Cell. 2017 Sep 1;28(18):2374-2385.
Title:	TRIM9-dependent ubiquitination of DCC constrains kinase signaling, exocytosis, and axon branching.
Author:	Plooster, Melissa\|Menon, Shalini\|Winkle, Cortney C\|Urbina, Fabio L\|Monkiewicz, Caroline\|Phend, Kristen D\|Weinberg, Richard J\|Gupton, Stephanie L
PMID:	28701345

211.
Journal:	Exp Cell Res. 2017 Oct 1;359(1):163-170.
Title:	Filamin A upregulation correlates with Snail-induced epithelial to mesenchymal transition (EMT) and cell adhesion but its inhibition increases the migration of colon adenocarcinoma HT29 cells.
Author:	Wieczorek, Katarzyna\|Wiktorska, Magdalena\|Sacewicz-Hofman, Izabela\|Boncela, Joanna\|Lewinski, Andrzej\|Kowalska, M Anna\|Niewiarowska, Jolanta
PMID:	28778796

212.
Journal:	J Physiol Pharmacol. 2017 Jun;68(3):375-383.
Title:	The C-terminal region of the focal adhesion kinase F1 domain binds Akt1 and inhibits pressure-induced cell adhesion.
Author:	Basson, M D\|Zeng, B\|Wang, S
PMID:	28820394

213.
Journal:	J Biol Chem. 2017 Sep 29;292(39):16321-16332.
Title:	Syndecan-2 cytoplasmic domain up-regulates matrix metalloproteinase-7 expression via the protein kinase Cgamma-mediated FAK/ERK signaling pathway in colon cancer.
Author:	Jang, Bohee\|Jung, Hyejung\|Choi, Sojoong\|Lee, Young Hun\|Lee, Seung-Taek\|Oh, Eok-Soo
PMID:	28821612

214.
Journal:	Drug Discov Ther. 2017;11(4):212-217.
Title:	Sushi repeat-containing protein X-linked 2 promotes angiogenesis through the urokinase-type plasminogen activator receptor dependent integrin alphavbeta3/focal adhesion kinase pathways.
Author:	Liu, Kuiliang\|Fan, Jianghao\|Wu, Jing
PMID:	28867754

215.
Journal:	Nutrients. 2017 Sep 27;9(10). pii: nu9101073.
Title:	Resveratrol Regulates Colorectal Cancer Cell Invasion by Modulation of Focal Adhesion Molecules.
Author:	Buhrmann, Constanze\|Shayan, Parviz\|Goel, Ajay\|Shakibaei, Mehdi
PMID:	28953264

216.
Journal:	Nutr Cancer. 2017 Oct;69(7):1043-1052.
Title:	Induction of Anoikis in Human Colorectal Cancer Cells by Fucoxanthinol.
Author:	Terasaki, Masaru\|Maeda, Hayato\|Miyashita, Kazuo\|Mutoh, Michihiro
PMID:	28990814

217.
Journal:	Cancer Sci. 2017 Dec;108(12):2405-2412.
Title:	Identification of zinc finger protein of the cerebellum 5 as a survival factor of prostate and colorectal cancer cells.
Author:	Satow, Reiko\|Inagaki, Shota\|Kato, Chiaki\|Shimozawa, Makoto\|Fukami, Kiyoko
PMID:	29024195

218.
Journal:	Sci Rep. 2017 Oct 24;7(1):13912.
Title:	Phosphoinositide-specific phospholipase Cgamma1 inhibition induces autophagy in human colon cancer and hepatocellular carcinoma cells.
Author:	Dai, Lianzhi\|Chen, Xiaolei\|Lu, Xiaohong\|Wang, Fen\|Zhan, Yanyan\|Song, Gang\|Hu, Tianhui\|Xia, Chun\|Zhang, Bing
PMID:	29066806

219.
Journal:	PLoS One. 2017 Nov 1;12(11):e0187173.
Title:	Evaluation of the efficacy of dasatinib, a Src/Abl inhibitor, in colorectal cancer cell lines and explant mouse model.
Author:	Scott, Aaron J\|Song, Eun-Kee\|Bagby, Stacey\|Purkey, Alicia\|McCarter, Martin\|Gajdos, Csaba\|Quackenbush, Kevin S\|Cross, Benjamin\|Pitts, Todd M\|Tan, Aik Choon\|Eckhardt, S Gail\|Fenton, Hubert\|Arcaroli, John\|Messersmith, Wells A
PMID:	29091939

220.
Journal:	J Gastrointest Cancer. 2017 Nov 7. pii: 10.1007/s12029-017-0024-9.
Title:	A Deregulated PI3K-AKT Signaling Pathway in Patients with Colorectal Cancer.
Author:	Zhang, Tao\|Ma, Yuanping\|Fang, Jiansong\|Liu, Chang\|Chen, Liangrong
PMID:	29110225

221.
Journal:	J BUON. 2017 Sep-Oct;22(5):1097-1106.
Title:	FAK, Src and p-Paxillin expression is decreased in liver metastasis of colorectal carcinoma patients.
Author:	Mantonakis, Eleftherios\|Giaginis, Constantinos\|Pikoulis, Emmanouel\|Felekouras, Evangelos\|Patsouris, Efstratios\|Liakakos, Theodoros\|Papalampros, Efstathios\|Theocharis, Stamatios
PMID:	29135089

222.
Journal:	Oncotarget. 2017 Aug 24;8(58):98051-98067.
Title:	Inhibition of pressure-activated cancer cell adhesion by FAK-derived peptides.
Author:	Zeng, Bixi\|Devadoss, Dinesh\|Wang, Shouye\|Vomhof-DeKrey, Emilie E\|Kuhn, Leslie A\|Basson, Marc D
PMID:	29228673

223.
Journal:	Oncol Res. 2018 Mar 5;26(2):209-217.
Title:	Procaine Inhibits the Proliferation and Migration of Colon Cancer Cells Through Inactivation of the ERK/MAPK/FAK Pathways by Regulation of RhoA.
Author:	Li, Chang\|Gao, Shuohui\|Li, Xiaoping\|Li, Chang\|Ma, Lianjun
PMID:	28492141

224.
Journal:	J Cell Mol Med. 2018 Jan;22(1):131-140.
Title:	CD155 knockdown promotes apoptosis via AKT/Bcl-2/Bax in colon cancer cells.
Author:	Zheng, Qianqian\|Wang, Biao\|Gao, Jian\|Xin, Na\|Wang, Wei\|Song, Xiaowen\|Shao, Yue\|Zhao, Chenghai
PMID:	28816021

225.
Journal:	Clin Cancer Res. 2018 Jan 15;24(2):433-444.
Title:	Monoclonal Antibodies Directed against Cadherin RGD Exhibit Therapeutic Activity against Melanoma and Colorectal Cancer Metastasis.
Author:	Bartolome, Ruben A\|Aizpurua, Carmen\|Jaen, Marta\|Torres, Sofia\|Calvino, Eva\|Imbaud, Juan I\|Casal, J Ignacio
PMID:	28916526

226.
Journal:	Mol Cancer Ther. 2018 Apr;17(4):806-813.
Title:	Wnt/beta-Catenin Pathway Activation Mediates Adaptive Resistance to BRAF Inhibition in Colorectal Cancer.
Author:	Chen, Guangming\|Gao, Chenxi\|Gao, Xuan\|Zhang, Dennis Han\|Kuan, Shih-Fan\|Burns, Timothy F\|Hu, Jing
PMID:	29167314

227.
Journal:	Biochem Pharmacol. 2018 Apr;150:191-201.
Title:	Natural small molecule bigelovin suppresses orthotopic colorectal tumor growth and inhibits colorectal cancer metastasis via IL6/STAT3 pathway.
Author:	Li, Mingyue\|Yue, Grace Gar-Lee\|Song, Li-Hua\|Huang, Mao-Bo\|Lee, Julia Kin-Ming\|Tsui, Stephen Kwok-Wing\|Fung, Kwok-Pui\|Tan, Ning-Hua\|Lau, Clara Bik-San
PMID:	29454618

228.
Journal:	Cell Discov. 2018 Feb 20;4:8.
Title:	The binding of DCC-P3 motif and FAK-FAT domain mediates the initial step of netrin-1/DCC signaling for axon attraction.
Author:	Xu, Shutong\|Liu, Yiqiong\|Li, Xiaolong\|Liu, Ying\|Meijers, Rob\|Zhang, Yan\|Wang, Jia-Huai
PMID:	29479476

229.
Journal:	Cell Death Dis. 2018 Apr 1;9(4):417.
Title:	CircHIPK3 promotes colorectal cancer growth and metastasis by sponging miR-7.
Author:	Zeng, Kaixuan\|Chen, Xiaoxiang\|Xu, Mu\|Liu, Xiangxiang\|Hu, Xiuxiu\|Xu, Tao\|Sun, Huiling\|Pan, Yuqin\|He, Bangshun\|Wang, Shukui
PMID:	29549306

230.
Journal:	Oncotarget. 2018 Feb 5;9(17):13551-13564.
Title:	Molecular profiling of ALDH1(+) colorectal cancer stem cells reveals preferential activation of MAPK, FAK, and oxidative stress pro-survival signalling pathways.
Author:	Vishnubalaji, Radhakrishnan\|Manikandan, Muthurangan\|Fahad, Mohamed\|Hamam, Rimi\|Alfayez, Musaad\|Kassem, Moustapha\|Aldahmash, Abdullah\|Alajez, Nehad M
PMID:	29568377

231.
Journal:	Mol Cancer Ther. 2018 Apr;17(4):719-723.
Title:	Adaptive Resistance to Chemotherapy, A Multi-FAK-torial Linkage.
Author:	Taylor, Kristin N\|Schlaepfer, David D
PMID:	29610281

232.
Journal:	Eur J Med Chem. 2018 May 25;152:31-52.
Title:	Structural-based design, synthesis, and antitumor activity of novel alloxazine analogues with potential selective kinase inhibition.
Author:	Malki, Waleed H\|Gouda, Ahmed M\|Ali, Hamdy E A\|Al-Rousan, Rabaa\|Samaha, Doaa\|Abdalla, Ashraf N\|Bustamante, Juan\|Abd Elmageed, Zakaria Y\|Ali, Hamed I
PMID:	29684708

233.
Journal:	Int J Mol Med. 2018 Jul;42(1):368-380.
Title:	Inflammatory genes are novel prognostic biomarkers for colorectal cancer.
Author:	Jiang, Hao\|Dong, Li\|Gong, Fangyan\|Gu, Yuping\|Zhang, Henghun\|Fan, Dong\|Sun, Zhiguo
PMID:	29693170

234.
Journal:	NPJ Precis Oncol. 2018 Jan 23;2(1):2.
Title:	Vasodilator-stimulated phosphoprotein promotes liver metastasis of gastrointestinal cancer by activating a beta1-integrin-FAK-YAP1/TAZ signaling pathway.
Author:	Xiang, Xiaoyu\|Wang, Yuanguo\|Zhang, Hongbin\|Piao, Jinhua\|Muthusamy, Selvaraj\|Wang, Lei\|Deng, Yibin\|Zhang, Wei\|Kuang, Rui\|Billadeau, Daniel D\|Huang, Shengbing\|Lai, Jinping\|Urrutia, Raul\|Kang, Ningling
PMID:	29872721

235.
Journal:	J Exp Clin Cancer Res. 2018 Jun 15;37(1):117.
Title:	Extracellular gamma-synuclein promotes tumor cell motility by activating beta1 integrin-focal adhesion kinase signaling pathway and increasing matrix metalloproteinase-24, -2 protein secretion.
Author:	Liu, Caiyun\|Qu, Like\|Zhao, Chuanke\|Shou, Chengchao
PMID:	29903032

236.
Journal:	Biochem Biophys Res Commun. 2018 Sep 5;503(2):843-848.
Title:	Acid ceramidase inhibition sensitizes human colon cancer cells to oxaliplatin through downregulation of transglutaminase 2 and beta1 integrin/FAK-mediated signalling.
Author:	Klobucar, Marko\|Grbcic, Petra\|Pavelic, Sandra Kraljevic\|Jonjic, Nives\|Visentin, Sarah\|Sedic, Mirela
PMID:	29920241

237.
Journal:	J Physiol Pharmacol. 2018 Apr;69(2).
Title:	Identification of potential small-molecule protein-protein inhibitors of cancer metastasis by 3D epitope-based computational screening.
Author:	Raschka, S\|More, S K\|Devadoss, D\|Zeng, B\|Kuhn, L A\|Basson, M D
PMID:	29980145

238.
Journal:	Anticancer Res. 2018 Aug;38(8):4667-4676.
Title:	Investigation into Enhancing Capecitabine Efficacy in Colorectal Cancer by Inhibiting Focal Adhesion Kinase Signaling.
Author:	Sim, Jae Jun\|Park, Min Hee\|Baek, Jeong-Heum\|Lee, Haejun\|Jeong, Keun-Yeong\|Kim, Hwan Mook
PMID:	30061234

239.
Journal:	Phytomedicine. 2018 Jul 15;46:131-141.
Title:	Turmeric extract, with absorbable curcumin, has potent anti-metastatic effect in vitro and in vivo.
Author:	Li, Mingyue\|Yue, Grace Gar-Lee\|Tsui, Stephen Kwok-Wing\|Fung, Kwok-Pui\|Lau, Clara Bik-San
PMID:	30097113

240.
Journal:	Mol Cancer Res. 2018 Aug 28. pii: 1541-7786.MCR-18-0199.
Title:	De Novo Fatty Acid Synthesis Driven Sphingolipid Metabolism Promotes Metastatic Potential of Colorectal Cancer.
Author:	Jafari, Naser\|Drury, James\|Morris, Andrew J\|Onono, Fredrick O\|Stevens, Payton D\|Gao, Tianyan\|Liu, Jinpeng\|Wang, Chi\|Lee, Eun Y\|Weiss, Heidi L\|Evers, B Mark\|Zaytseva, Yekaterina Y
PMID:	30154249

241.
Journal:	J Drug Target. 2018 Sep 12:1-19.
Title:	The roles and mechanisms of G3BP1 in tumour promotion.
Author:	Zhang, Cong-Hui\|Wang, Jun-Xia\|Cai, Mei-Lian\|Shao, Rongguang\|Liu, Hong\|Zhao, Wu-Li
PMID:	30207743

242.
Journal:	J Cell Biochem. 2018 Sep 14.
Title:	Matrix stiffness mediates stemness characteristics via activating the Yes-associated protein in colorectal cancer cells.
Author:	Tan, Fengbo\|Huang, Yan\|Pei, Qian\|Liu, Heli\|Pei, Haiping\|Zhu, Hong
PMID:	30218452

243.
Journal:	World J Gastroenterol. 2018 Sep 14;24(34):3884-3897.
Title:	Formin-like 3 regulates RhoC/FAK pathway and actin assembly to promote cell invasion in colorectal carcinoma.
Author:	Zeng, Yuan-Feng\|Xiao, Yi-Sheng\|Liu, Yong\|Luo, Xiao-Jiang\|Wen, Li-Dan\|Liu, Qian\|Chen, Min
PMID:	30228782

244.
Journal:	Oncogenesis. 2018 Sep 24;7(9):76.
Title:	Endothelial cell activation on 3D-matrices derived from PDGF-BB-stimulated fibroblasts is mediated by Snail1.
Author:	Herrera, Alberto\|Herrera, Mercedes\|Guerra-Perez, Natalia\|Galindo-Pumarino, Cristina\|Larriba, Maria Jesus\|Garcia-Barberan, Vanesa\|Gil, Beatriz\|Gimenez-Moyano, Sara\|Ferreiro-Monteagudo, Reyes\|Veguillas, Pilar\|Candia, Antonio\|Pena, Raul\|Pinto, Jesus\|Garcia-B
PMID:	30250018

245.
Journal:	BMB Rep. 2018 Oct 1.
Title:	STK899704 inhibits stemness of cancer stem cells and migration via the FAK-MEK-ERK pathway in HT29 cells.
Author:	Jang, Hui-Ju\|Bak, Yesol\|Pham, Thu-Huyen\|Kwon, Sae-Bom\|Kim, Bo-Yeon\|Hong, JinTae\|Yoon, Do-Young
PMID:	30269740

246.
Journal:	Toxicol Appl Pharmacol. 2018 Oct 4;360:131-140.
Title:	FAK alleviates radiation-induced rectal injury by decreasing apoptosis.
Author:	Li, Jun-Jun\|Tu, Wen-Zhi\|Chen, Xu-Ming\|Ying, Hou-Yu\|Chen, Ying\|Ge, Yu-Long\|Wang, Jing\|Xu, Yi\|Chen, Ting-Feng\|Zhang, Xiao-Wei\|Ye, Jin-Jun\|Liu, Yong
PMID:	30292832

247.
Journal:	World J Gastrointest Oncol. 2018 Oct 15;10(10):290-292.
Title:	Inhibiting focal adhesion kinase: A potential target for enhancing therapeutic efficacy in colorectal cancer therapy.
Author:	Jeong, Keun-Yeong
PMID:	30364839

248.
Journal:	Int J Oncol. 2018 Oct 25.
Title:	Sphingosine kinase 1 promotes the metastasis of colorectal cancer by inducing the epithelialmesenchymal transition mediated by the FAK/AKT/MMPs axis.
Author:	Liu, Shi-Quan\|Xu, Chun-Yan\|Wu, Wen-Hong\|Fu, Zhen-Hua\|He, Si-Wei\|Qin, Meng-Bin\|Huang, Jie-An
PMID:	30365116