Primary Site >> Colorectal Cancer

Gene >> PTGES

Journal: Oncogene. 1999 Jan 14;18(2):305-14.
Title: Regulation of cyclooxygenase-2 pathway by HER2 receptor.
Author: Vadlamudi, R|Mandal, M|Adam, L|Steinbach, G|Mendelsohn, J|Kumar, R
PMID: 9927187
Journal: Clin Cancer Res. 2001 Dec;7(12):3971-6.
Title: Inducible microsomal prostaglandin E synthase is overexpressed in colorectal adenomas and cancer.
Author: Yoshimatsu, K|Golijanin, D|Paty, P B|Soslow, R A|Jakobsson, P J|DeLellis, R A|Subbaramaiah, K|Dannenberg, A J
PMID: 11751489
Journal: Biochem Pharmacol. 2003 Jul 1;66(1):51-61.
Title: Positive and negative regulation of prostaglandin E2 biosynthesis in human colorectal carcinoma cells by cancer chemopreventive agents.
Author: Sherratt, Philip J|McLellan, Lesley I|Hayes, John D
PMID: 12818365
Journal: J Biol Chem. 2003 Sep 26;278(39):37937-47.
Title: Cellular prostaglandin E2 production by membrane-bound prostaglandin E synthase-2 via both cyclooxygenases-1 and -2.
Author: Murakami, Makoto|Nakashima, Karin|Kamei, Daisuke|Masuda, Seiko|Ishikawa, Yukio|Ishii, Toshiharu|Ohmiya, Yoshihiro|Watanabe, Kikuko|Kudo, Ichiro
PMID: 12835322
Journal: J Biol Chem. 2003 May 23;278(21):19396-405. Epub 2003 Mar 7.
Title: Potential role of microsomal prostaglandin E synthase-1 in tumorigenesis.
Author: Kamei, Daisuke|Murakami, Makoto|Nakatani, Yoshihito|Ishikawa, Yukio|Ishii, Toshiharu|Kudo, Ichiro
PMID: 12626523
Journal: J Lipid Res. 2006 May;47(5):1071-80. Epub 2006 Feb 22.
Title: 15-deoxy-Delta12,14-prostaglandin J2 inhibits the expression of microsomal prostaglandin E synthase type 2 in colon cancer cells.
Author: Schroder, Oliver|Yudina, Yulyana|Sabirsh, Alan|Zahn, Nadine|Haeggstrom, Jesper Z|Stein, Jurgen
PMID: 16495511
Journal: Korean J Gastroenterol. 2008 May;51(5):274-9.
Title: [Role of prostaglandins in colon cancer].
Author: Myung, Seung-Jae|Kim, In-Hwa
PMID: 18516010
Journal: Biochem Biophys Res Commun. 2008 Jul 18;372(1):249-53.
Title: Genetic deletion of mPGES-1 accelerates intestinal tumorigenesis in APC(Min/+) mice.
Author: Elander, N|Ungerback, J|Olsson, H|Uematsu, S|Akira, S|Soderkvist, P
PMID: 18485889
Journal: Antioxid Redox Signal. 2008 Sep;10(9):1491-500.
Title: GPx2 counteracts PGE2 production by dampening COX-2 and mPGES-1 expression in human colon cancer cells.
Author: Banning, Antje|Florian, Simone|Deubel, Stefanie|Thalmann, Sophie|Muller-Schmehl, Katrin|Jacobasch, Gisela|Brigelius-Flohe, Regina
PMID: 18479189
Journal: Cancer Res. 2008 May 1;68(9):3251-9.
Title: Genetic deletion of mPGES-1 suppresses intestinal tumorigenesis.
Author: Nakanishi, Masako|Montrose, David C|Clark, Patsy|Nambiar, Prashant R|Belinsky, Glenn S|Claffey, Kevin P|Xu, Daigen|Rosenberg, Daniel W
PMID: 18451151
Journal: Mol Carcinog. 2008 Jun;47(6):466-77.
Title: 15-Hydroxyprostaglandin dehydrogenase suppresses K-RasV12-dependent tumor formation in Nu/Nu mice.
Author: Pham, Hung|Eibl, Guido|Vincenti, Romina|Chong, Benny|Tai, Hsin-Hsiung|Slice, Lee W
PMID: 18058808
Journal: Mol Carcinog. 2009 May;48(5):401-7.
Title: Association between adenomatosis polyposis coli functional status and microsomal prostaglandin E synthase-1 expression in colorectal cancer.
Author: Elander, Nils|Zhou, Jianlin|Ungerback, Jonas|Dimberg, Jan|Soderkvist, Peter
PMID: 19035518
Journal: Virchows Arch. 2009 Jun;454(6):667-76.
Title: Microsomal prostaglandin E synthase protein levels correlate with prognosis in colorectal cancer patients.
Author: Seo, Tsuguhiko|Tatsuguchi, Atsushi|Shinji, Seiichi|Yonezawa, Masaoki|Mitsui, Keigo|Tanaka, Shu|Fujimori, Shunji|Gudis, Katya|Fukuda, Yuh|Sakamoto, Choitsu
PMID: 19412621
Journal: Pancreas. 2010 Apr;39(3):332-9.
Title: Loss of 15-hydroxyprostaglandin dehydrogenase increases prostaglandin E2 in pancreatic tumors.
Author: Pham, Hung|Chen, Monica|Li, Aihua|King, Jonathan|Angst, Eliane|Dawson, David W|Park, Jenny|Reber, Howard A|Hines, O Joe|Eibl, Guido
PMID: 19820419
Journal: Int J Oncol. 2010 Feb;36(2):469-78.
Title: Receptor and enzyme expression for prostanoid metabolism in colorectal cancer related to tumor tissue PGE2.
Author: Gustafsson, Annika|Andersson, Marianne|Lagerstedt, Kristina|Lonnroth, Christina|Nordgren, Svante|Lundholm, Kent
PMID: 20043083
Journal: Biochimie. 2010 Jun;92(6):660-4.
Title: mPGES-1 as a target for cancer suppression: A comprehensive invited review "Phospholipase A2 and lipid mediators".
Author: Nakanishi, Masako|Gokhale, Vijay|Meuillet, Emmanuelle J|Rosenberg, Daniel W
PMID: 20159031
Journal: Yonsei Med J. 2010 Sep;51(5):692-9.
Title: Impacts of cytosolic phospholipase A2, 15-prostaglandin dehydrogenase, and cyclooxygenase-2 expressions on tumor progression in colorectal cancer.
Author: Lim, Sung Chul|Cho, Hoon|Lee, Tae Bum|Choi, Cheol Hee|Min, Young Don|Kim, Sung Soo|Kim, Kyung Jong
PMID: 20635443
Journal: Clin Cancer Res. 2010 Aug 15;16(16):4207-16.
Title: Inhibition of hypoxia inducible factor-1alpha by dihydroxyphenylethanol, a product from olive oil, blocks microsomal prostaglandin-E synthase-1/vascular endothelial growth factor expression and reduces tumor angiogenesis.
Author: Terzuoli, Erika|Donnini, Sandra|Giachetti, Antonio|Iniguez, Miguel A|Fresno, Manuel|Melillo, Giovanni|Ziche, Marina
PMID: 20682710
Journal: Inflamm Bowel Dis. 2011 Mar;17(3):696-710.
Title: Role of different inflammatory and tumor biomarkers in the development of ulcerative colitis-associated carcinogenesis.
Author: Talero, E|Sanchez-Fidalgo, S|Villegas, I|de la Lastra, C Alarcon|Illanes, M|Motilva, V
PMID: 20722052
Journal: Cancer Prev Res (Phila). 2011 Aug;4(8):1198-208.
Title: Selective PGE(2) suppression inhibits colon carcinogenesis and modifies local mucosal immunity.
Author: Nakanishi, Masako|Menoret, Antoine|Tanaka, Takuji|Miyamoto, Shingo|Montrose, David C|Vella, Anthony T|Rosenberg, Daniel W
PMID: 21576350
Journal: Invest New Drugs. 2012 Oct;30(5):1865-77.
Title: Identification of a novel class of anti-inflammatory compounds with anti-tumor activity in colorectal and lung cancers.
Author: Chang, Hui-Hua|Song, Zuohe|Wisner, Lee|Tripp, Tina|Gokhale, Vijay|Meuillet, Emmanuelle J
PMID: 21931968
Journal: Oncogene. 2012 Jun 14;31(24):2943-52.
Title: Microsomal prostaglandin E synthase-1 is involved in multiple steps of colon carcinogenesis.
Author: Sasaki, Y|Kamei, D|Ishikawa, Y|Ishii, T|Uematsu, S|Akira, S|Murakami, M|Hara, S
PMID: 21986945
Journal: Carcinogenesis. 2013 Jan;34(1):163-9.
Title: Hypoxia-inducible factor-2alpha is essential in activating the COX2/mPGES-1/PGE2 signaling axis in colon cancer.
Author: Xue, Xiang|Shah, Yatrik M
PMID: 23042097
Journal: Cancer Prev Res (Phila). 2014 Mar;7(3):300-9.
Title: Raloxifene and antiestrogenic gonadorelin inhibits intestinal tumorigenesis by modulating immune cells and decreasing stem-like cells.
Author: Janakiram, Naveena B|Mohammed, Altaf|Brewer, Misty|Bryant, Taylor|Biddick, Laura|Lightfoot, Stan|Pathuri, Gopal|Gali, Hariprasad|Rao, Chinthalapally V
PMID: 24431404
Journal: Life Sci. 2014 Oct 22;116(1):43-50.
Title: Prostaglandin E2 produced by inducible COX-2 and mPGES-1 promoting cancer cell proliferation in vitro and in vivo.
Author: Ruan, Diana|So, Shui-Ping
PMID: 25139833
Journal: Prostaglandins Other Lipid Mediat. 2015 Jul;120:161-5.
Title: Inhibition of microsomal prostaglandin E synthase-1 as targeted therapy in cancer treatment.
Author: Larsson, Karin|Jakobsson, Per-Johan
PMID: 26100239
Journal: Oncotarget. 2015 Nov 24;6(37):39941-59.
Title: Prostaglandins induce early growth response 1 transcription factor mediated microsomal prostaglandin E2 synthase up-regulation for colorectal cancer progression.
Author: Stamatakis, Konstantinos|Jimenez-Martinez, Marta|Jimenez-Segovia, Alba|Chico-Calero, Isabel|Conde, Elisa|Galan-Martinez, Javier|Ruiz, Julia|Pascual, Alejandro|Barrocal, Beatriz|Lopez-Perez, Ricardo|Garcia-Bermejo, Maria Laura|Fresno, Manuel
PMID: 26498686
Journal: Prostaglandins Other Lipid Mediat. 2015 Sep;121(Pt A):42-5.
Title: Role of microsomal prostaglandin E synthase-1 (mPGES-1)-derived prostaglandin E2 in colon carcinogenesis.
Author: Sasaki, Yuka|Nakatani, Yoshihito|Hara, Shuntaro
PMID: 26150361
Journal: PLoS One. 2015 Apr 17;10(4):e0123256.
Title: Growth inhibitory effect of polyunsaturated fatty acids (PUFAs) on colon cancer cells via their growth inhibitory metabolites and fatty acid composition changes.
Author: Zhang, Chengcheng|Yu, Haining|Ni, Xiaofeng|Shen, Shengrong|Das, Undurti N
PMID: 25886460
Journal: Mol Oncol. 2015 Aug;9(7):1252-8.
Title: Instability of a dinucleotide repeat in the 3'-untranslated region (UTR) of the microsomal prostaglandin E synthase-1 (mPGES-1) gene in microsatellite instability-high (MSI-H) colorectal carcinoma.
Author: Cherukuri, Durga Prasad|Deignan, Joshua L|Das, Kingshuk|Grody, Wayne W|Herschman, Harvey
PMID: 25817443
Journal: Oncogene. 2016 Jun 30;35(26):3365-75.
Title: Radiation promotes colorectal cancer initiation and progression by inducing senescence-associated inflammatory responses.
Author: Kim, S B|Bozeman, R G|Kaisani, A|Kim, W|Zhang, L|Richardson, J A|Wright, W E|Shay, J W
PMID: 26477319
Journal: Hum Exp Toxicol. 2017 Jul;36(7):692-700.
Title: Garcinol exhibits anti-proliferative activities by targeting microsomal prostaglandin E synthase-1 in human colon cancer cells.
Author: Ranjbarnejad, T|Saidijam, M|Tafakh, M Sadat|Pourjafar, M|Talebzadeh, F|Najafi, R
PMID: 27481098
Journal: Prostaglandins Other Lipid Mediat. 2017 Jul;131:1-8.
Title: Methanolic extract of Boswellia serrata exhibits anti-cancer activities by targeting microsomal prostaglandin E synthase-1 in human colon cancer cells.
Author: Ranjbarnejad, Tayebeh|Saidijam, Massoud|Moradkhani, Shirin|Najafi, Rezvan
PMID: 28549801
Journal: BMC Cancer. 2017 Dec 13;17(1):844.
Title: A network-based predictive gene-expression signature for adjuvant chemotherapy benefit in stage II colorectal cancer.
Author: Cao, Bangrong|Luo, Liping|Feng, Lin|Ma, Shiqi|Chen, Tingqing|Ren, Yuan|Zha, Xiao|Cheng, Shujun|Zhang, Kaitai|Chen, Changmin
PMID: 29237416
Journal: World J Surg. 2018 Apr;42(4):953-964.
Title: Anti-inflammatory Effects of Enhanced Recovery Programs on Early-Stage Colorectal Cancer Surgery.
Author: Venara, Aurelien|Duchalais, Emilie|Dariel, Anne|Aubert, Philippe|Durand, Tony|Meurette, Guillaume|Rolli-Derkinderen, Malvyne|Hamy, Antoine|Neunlist, Michel
PMID: 28983734
Journal: Cells Tissues Organs. 2018 Jul 24:1-8.
Title: Sulforaphane, a Chemopreventive Compound, Inhibits Cyclooxygenase-2 and Microsomal Prostaglandin E Synthase-1 Expression in Human HT-29 Colon Cancer Cells.
Author: Tafakh, Maryam Sadat|Saidijam, Massoud|Ranjbarnejad, Tayebeh|Malih, Sara|Mirzamohammadi, Solmaz|Najafi, Rezvan
PMID: 30041241