Literatures

Primary Site >> Colorectal Cancer

Gene >> PTGER4

1.
Journal:	Langenbecks Arch Chir. 1996;381(1):51-8.
Title:	[Tumor cell dissemination in bone marrow and peritoneal cavity. An immunocytochemical study of patients with stomach or colorectal carcinoma].
Author:	Broll, R\|Lembcke, K\|Stock, C\|Zingler, M\|Duchrow, M\|Schimmelpenning, H\|Strik, M\|Muller, G\|Kujath, P\|Bruch, H P
PMID:	8717176

2.
Journal:	Electrophoresis. 1997 Dec;18(15):2842-8.
Title:	Standardized characterization of gene expression in human colorectal epithelium by two-dimensional electrophoresis.
Author:	Reymond, M A\|Sanchez, J C\|Hughes, G J\|Gunther, K\|Riese, J\|Tortola, S\|Peinado, M A\|Kirchner, T\|Hohenberger, W\|Hochstrasser, D F\|Kockerling, F
PMID:	9504818

3.
Journal:	Eur J Pharmacol. 1999 Feb 12;367(1):131-8.
Title:	Nonsteroidal anti-inflammatory drugs may prevent colon cancer through suppression of hepatocyte growth factor expression.
Author:	Ota, S\|Tanaka, Y\|Bamba, H\|Kato, A\|Matsuzaki, F
PMID:	10082276

4.
Journal:	J Exp Clin Cancer Res. 2000 Jun;19(2):219-23.
Title:	Effect of prostaglandin E1 on vascular endothelial growth factor production by human macrophages and colon cancer cells.
Author:	Bamba, H\|Ota, S\|Kato, A\|Kawamoto, C\|Matsuzaki, F
PMID:	10965822

5.
Journal:	J Cancer Res Clin Oncol. 2001 Aug;127(8):489-94.
Title:	Immunobead RT-PCR versus regular RT-PCR amplification of CEA mRNA in peripheral blood.
Author:	Park, S\|Lee, B\|Kim, I\|Choi, I\|Hong, K\|Ryu, Y\|Rhim, J\|Shin, J\|Park, S C\|Chung, H\|Chung, J
PMID:	11501748

6.
Journal:	Proc Natl Acad Sci U S A. 2003 Jul 22;100(15):8921-6.
Title:	Inhibition of apoptosis in normal and transformed intestinal epithelial cells by cAMP through induction of inhibitor of apoptosis protein (IAP)-2.
Author:	Nishihara, Hiroshi\|Kizaka-Kondoh, Shinae\|Insel, Paul A\|Eckmann, Lars
PMID:	12837940

7.
Journal:	J Biol Chem. 2004 Jul 9;279(28):29797-804. Epub 2004 May 3.
Title:	Colon carcinoma cell growth is associated with prostaglandin E2/EP4 receptor-evoked ERK activation.
Author:	Pozzi, Ambra\|Yan, Xuexian\|Macias-Perez, Ines\|Wei, Shouzuo\|Hata, Aaron N\|Breyer, Richard M\|Morrow, Jason D\|Capdevila, Jorge H
PMID:	15123663

8.
Journal:	J Lab Clin Med. 2004 Jun;143(6):344-51.
Title:	Tissue preparation for gene expression profiling of colorectal carcinoma: three alternatives to laser microdissection with preamplification.
Author:	Croner, Roland S\|Guenther, Klaus\|Foertsch, Thomas\|Siebenhaar, Renate\|Brueckl, Wolfgang M\|Stremmel, Christian\|Hlubek, Falk\|Hohenberger, Werner\|Reingruber, Bertram
PMID:	15192650

9.
Journal:	J Gastroenterol Hepatol. 2005 Aug;20(8):1279-84.
Title:	Detection of cytokeratin 20 mRNA in the peripheral blood of patients with colorectal cancer by immunomagnetic bead enrichment and real-time reverse transcriptase-polymeras chain reaction.
Author:	Guo, Junming\|Xiao, Bingxiu\|Jin, Zhijin\|Qin, Lijun\|Chen, Jian\|Chen, Hui\|Zhang, Xinjun\|Liu, Zhong
PMID:	16048578

10.
Journal:	Inflamm Bowel Dis. 2006 Mar;12(3):153-65.
Title:	Defective arachidonate release and PGE2 production in Gi alpha2-deficient intestinal and colonic subepithelial myofibroblasts.
Author:	Edwards, Robert Andrew\|Smock, Andrew Zoller
PMID:	16534415

11.
Journal:	Cancer Res. 2006 Mar 15;66(6):3106-13.
Title:	Increased EP4 receptor expression in colorectal cancer progression promotes cell growth and anchorage independence.
Author:	Chell, Simon D\|Witherden, Ian R\|Dobson, Richard R\|Moorghen, Morganaden\|Herman, Andrew A\|Qualtrough, David\|Williams, Ann C\|Paraskeva, Christos
PMID:	16540660

12.
Journal:	Curr Pharm Des. 2006;12(19):2375-82.
Title:	Roles of prostanoids in colon carcinogenesis and their potential targeting for cancer chemoprevention.
Author:	Mutoh, Michihiro\|Takahashi, Mami\|Wakabayashi, Keiji
PMID:	16842185

13.
Journal:	Adv Anat Pathol. 2006 Sep;13(5):270-4.
Title:	Signal transduction cross-talk during colorectal tumorigenesis.
Author:	Liu, Xiuli\|Lazenby, Audrey J\|Siegal, Gene P
PMID:	16998321

14.
Journal:	Cancer Res. 2006 Oct 1;66(19):9665-72.
Title:	Host and direct antitumor effects and profound reduction in tumor metastasis with selective EP4 receptor antagonism.
Author:	Yang, Li\|Huang, Yuhui\|Porta, Rut\|Yanagisawa, Kiyoshi\|Gonzalez, Adriana\|Segi, Eric\|Johnson, David H\|Narumiya, Shuh\|Carbone, David P
PMID:	17018624

15.
Journal:	Oncogene. 2007 May 10;26(21):3006-19.
Title:	Prostaglandin E2-EP4 receptor signalling promotes tumorigenic behaviour of HT-29 human colorectal cancer cells.
Author:	Hawcroft, G\|Ko, C W S\|Hull, M A
PMID:	17130837

16.
Journal:	Cancer Res. 2007 Sep 15;67(18):8565-73.
Title:	Deletion of the AU-rich RNA binding protein Apobec-1 reduces intestinal tumor burden in Apc(min) mice.
Author:	Blanc, Valerie\|Henderson, Jeffrey O\|Newberry, Rodney D\|Xie, Yan\|Cho, Soo-Jin\|Newberry, Elizabeth P\|Kennedy, Susan\|Rubin, Deborah C\|Wang, Hanlin L\|Luo, Jianyang\|Davidson, Nicholas O
PMID:	17875695

17.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2007 Oct;293(4):G673-81.
Title:	PGE2 inhibits apoptosis in human adenocarcinoma Caco-2 cell line through Ras-PI3K association and cAMP-dependent kinase A activation.
Author:	Leone, Vincenza\|di Palma, Antonella\|Ricchi, Paolo\|Acquaviva, Fabio\|Giannouli, Maria\|Di Prisco, Anna Maria\|Iuliano, Francesca\|Acquaviva, Angela M
PMID:	17640974

18.
Journal:	Exp Cell Res. 2007 Aug 15;313(14):2969-79.
Title:	The EP4 receptor antagonist, L-161,982, blocks prostaglandin E2-induced signal transduction and cell proliferation in HCA-7 colon cancer cells.
Author:	Cherukuri, Durga Prasad\|Chen, Xiao B O\|Goulet, Anne-Christine\|Young, Robert N\|Han, Yongxin\|Heimark, Ronald L\|Regan, John W\|Meuillet, Emmanuelle\|Nelson, Mark A
PMID:	17631291

19.
Journal:	Biochem Biophys Res Commun. 2007 Aug 3;359(3):568-73.
Title:	Indomethacin decreases EP2 prostanoid receptor expression in colon cancer cells.
Author:	Fujino, Hiromichi\|Chen, Xiao-bo\|Regan, John W\|Murayama, Toshihiko
PMID:	17555711

20.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2007 Jun;292(6):G1511-9.
Title:	Decreased MAPK- and PGE2-dependent IL-11 production in Gialpha2-/- colonic myofibroblasts.
Author:	Hoang, Brian\|Trinh, Alice\|Birnbaumer, Lutz\|Edwards, Robert A
PMID:	17332478

21.
Journal:	Mol Cancer. 2007 Jan 3;6:2.
Title:	Gene expression profiles of primary colorectal carcinomas, liver metastases, and carcinomatoses.
Author:	Kleivi, Kristine\|Lind, Guro E\|Diep, Chieu B\|Meling, Gunn I\|Brandal, Lin T\|Nesland, Jahn M\|Myklebost, Ola\|Rognum, Torleiv O\|Giercksky, Karl-Erik\|Skotheim, Rolf I\|Lothe, Ragnhild A
PMID:	17201907

22.
Journal:	Mod Pathol. 2008 Jan;21(1):15-21.
Title:	Prostanoid receptor EP1 expression in breast cancer.
Author:	Thorat, Mangesh A\|Morimiya, Akira\|Mehrotra, Sanjana\|Konger, Raymond\|Badve, Sunil S
PMID:	17906615

23.
Journal:	RNA. 2008 Jul;14(7):1424-32.
Title:	Extracellular plasma RNA from colon cancer patients is confined in a vesicle-like structure and is mRNA-enriched.
Author:	Garcia, Jose Miguel\|Garcia, Vanesa\|Pena, Cristina\|Dominguez, Gemma\|Silva, Javier\|Diaz, Raquel\|Espinosa, Pablo\|Citores, Maria Jesus\|Collado, Manuel\|Bonilla, Felix
PMID:	18456845

24.
Journal:	APMIS. 2008 Jun;116(6):445-56.
Title:	Dendritic cell infiltration pattern along the colorectal adenoma-carcinoma sequence.
Author:	Yuan, Aping\|Steigen, Sonja E\|Goll, Rasmus\|Vonen, Barthold\|Husbekk, Anne\|Cui, Guanglin\|Florholmen, Jon
PMID:	18754318

25.
Journal:	BMC Cancer. 2009 Jun 26;9:207.
Title:	Proneoplastic effects of PGE2 mediated by EP4 receptor in colorectal cancer.
Author:	Doherty, Glen A\|Byrne, Sinead M\|Molloy, Eamonn S\|Malhotra, Vikrum\|Austin, Sandra C\|Kay, Elaine W\|Murray, Frank E\|Fitzgerald, Desmond J
PMID:	19558693

26.
Journal:	Cancer Biol Ther. 2010 Nov 15;10(10):1056-66.
Title:	The induction of S100p expression by the Prostaglandin E(2) (PGE(2))/EP4 receptor signaling pathway in colon cancer cells.
Author:	Chandramouli, Anupama\|Mercado-Pimentel, Melania E\|Hutchinson, Anthony\|Gibadulinova, Adriana\|Olson, Erik R\|Dickinson, Sally\|Shanas, Renee\|Davenport, Jennifer\|Owens, Janae\|Bhattacharyya, Achyut K\|Regan, John W\|Pastorekova, Silvia\|Arumugam, Thiruvengadam\|Log
PMID:	20890108

27.
Journal:	Arch Toxicol. 2010 Sep;84(9):731-40.
Title:	EP4 upregulation of Ras signaling and feedback regulation of Ras in human colon tissues and cancer cells.
Author:	Wu, Cheng-Hsun\|Shih, Yuan-Wei\|Chang, Chun-Hua\|Ou, Ting-Tsz\|Huang, Chi-Chou\|Hsu, Jeng-Dong\|Wang, Chau-Jong
PMID:	20571779

28.
Journal:	BMC Gastroenterol. 2010 Jan 26;10:9.
Title:	Prostaglandin E2-induced colonic secretion in patients with and without colorectal neoplasia.
Author:	Kaltoft, Nicolai\|Tilotta, Maria C\|Witte, Anne-Barbara\|Osbak, Philip S\|Poulsen, Steen S\|Bindslev, Niels\|Hansen, Mark B
PMID:	20100359

29.
Journal:	Neoplasia. 2010 Aug;12(8):618-27.
Title:	Effect of eicosapentaenoic acid on E-type prostaglandin synthesis and EP4 receptor signaling in human colorectal cancer cells.
Author:	Hawcroft, Gillian\|Loadman, Paul M\|Belluzzi, Andrea\|Hull, Mark A
PMID:	20689756

30.
Journal:	Cancer Biol Ther. 2012 Feb 1;13(3):175-83.
Title:	MicroRNA-101 (miR-101) post-transcriptionally regulates the expression of EP4 receptor in colon cancers.
Author:	Chandramouli, Anupama\|Onyeagucha, Benjamin Chidi\|Mercado-Pimentel, Melania E\|Stankova, Lenka\|Shahin, Nisreen Abu\|LaFleur, Bonnie J\|Heimark, Ronald L\|Bhattacharyya, Achyut K\|Nelson, Mark A
PMID:	22353936

31.
Journal:	Cancer Prev Res (Phila). 2012 Jun;5(6):855-63.
Title:	A study of prostaglandin pathway genes and interactions with current nonsteroidal anti-inflammatory drug use in colorectal adenoma.
Author:	Edwards, Todd L\|Shrubsole, Martha J\|Cai, Qiuyin\|Li, Guoliang\|Dai, Qi\|Rex, Douglas K\|Ulbright, Thomas M\|Fu, Zhenming\|Murff, Harvey J\|Smalley, Walter\|Ness, Reid\|Zheng, Wei
PMID:	22551900

32.
Journal:	Biochim Biophys Acta. 2012 Sep;1821(9):1224-34.
Title:	HT-29 human colon cancer cell proliferation is regulated by cytosolic phospholipase A(2)alpha dependent PGE(2)via both PKA and PKB pathways.
Author:	Kisslov, Liz\|Hadad, Nurit\|Rosengraten, Marina\|Levy, Rachel
PMID:	22728329

33.
Journal:	Cancer Genet. 2012 Oct;205(10):501-7.
Title:	Association of polymorphisms in microRNA-binding sites and colorectal cancer in an Iranian population.
Author:	Azimzadeh, Pedram\|Romani, Sara\|Mohebbi, Seyed Reza\|Mahmoudi, Touraj\|Vahedi, Mohsen\|Fatemi, Seyed Reza\|Zali, Narges\|Zali, Mohammad Reza
PMID:	22939228

34.
Journal:	Int J Cancer. 2013 Aug 15;133(4):825-34.
Title:	Targeting the EP1 receptor reduces Fas ligand expression and increases the antitumor immune response in an in vivo model of colon cancer.
Author:	O'Callaghan, Grace\|Ryan, Aideen\|Neary, Peter\|O'Mahony, Caitlin\|Shanahan, Fergus\|Houston, Aileen
PMID:	23390011

35.
Journal:	Hinyokika Kiyo. 2013 Feb;59(2):83-9.
Title:	[Expression and function of E prostanoid receptors in urological cancer].
Author:	Ohba, Kojiro\|Miyata, Yasuyoshi\|Sakai, Hideki
PMID:	23552749

36.
Journal:	Eur J Pharmacol. 2013 Oct 15;718(1-3):408-17.
Title:	Induction of cyclooxygenase-2 expression by prostaglandin E2 stimulation of the prostanoid EP4 receptor via coupling to Galphai and transactivation of the epidermal growth factor receptor in HCA-7 human colon cancer cells.
Author:	Yoshida, Kenji\|Fujino, Hiromichi\|Otake, Sho\|Seira, Naofumi\|Regan, John W\|Murayama, Toshihiko
PMID:	23973650

37.
Journal:	Free Radic Res. 2014 Nov;48(11):1311-21.
Title:	Generation of ROS by CAY10598 leads to inactivation of STAT3 signaling and induction of apoptosis in human colon cancer HCT116 cells.
Author:	Chae, I G\|Kim, D-H\|Kundu, J\|Jeong, C-H\|Kundu, J K\|Chun, K-S
PMID:	25096910

38.
Journal:	Am J Cancer Res. 2015 May 15;5(6):2012-21. eCollection 2015.
Title:	Cyclooxygenase-2 knockdown using retinoic acid chalcone (RAC), a promising therapeutic strategy for colon cancer.
Author:	Jiang, Chao\|Wang, Qiong\|Xu, Zhe\|Li, Wei-Su\|Chen, Che\|Yao, Xue-Quan\|Liu, Fu-Kun
PMID:	26269760

39.
Journal:	Eur J Pharmacol. 2015 Dec 5;768:149-59.
Title:	Prostaglandin E2-stimulated prostanoid EP4 receptors induce prolonged de novo prostaglandin E2 synthesis through biphasic phosphorylation of extracellular signal-regulated kinases mediated by activation of protein kinase A in HCA-7 human colon cancer cell
Author:	Fujino, Hiromichi\|Seira, Naofumi\|Kurata, Naoki\|Araki, Yumi\|Nakamura, Hiroyuki\|Regan, John W\|Murayama, Toshihiko
PMID:	26518053

40.
Journal:	Oncotarget. 2015 Oct 20;6(32):33500-11.
Title:	Prostaglandin E receptor 4 (EP4) promotes colonic tumorigenesis.
Author:	Chang, Jian\|Vacher, Jean\|Yao, Bing\|Fan, Xiaofeng\|Zhang, Bixiang\|Harris, Raymond C\|Zhang, Ming-Zhi
PMID:	26378024

41.
Journal:	Mol Med Rep. 2015 Nov;12(5):7169-75.
Title:	Upregulation of C-C chemokine receptor type 7 expression by membrane-associated prostaglandin E synthase-1/prostaglandin E2 requires glycogen synthase kinase 3beta-mediated signal transduction in colon cancer cells.
Author:	Yu, Shuyi\|Hou, Qian\|Sun, Huiping\|Liu, Jianping\|Li, Jianzhe
PMID:	26352871

42.
Journal:	Gastroenterology. 2015 Dec;149(7):1884-1895.e4.
Title:	Prostaglandin E2 Promotes Colorectal Cancer Stem Cell Expansion and Metastasis in Mice.
Author:	Wang, Dingzhi\|Fu, Lingchen\|Sun, Haiyan\|Guo, Lixia\|DuBois, Raymond N
PMID:	26261008

43.
Journal:	Pharmacol Res Perspect. 2015 Feb;3(1):e00083.
Title:	Cellular density-dependent down-regulation of EP4 prostanoid receptors via the up-regulation of hypoxia-inducible factor-1alpha in HCA-7 human colon cancer cells.
Author:	Otake, Sho\|Yoshida, Kenji\|Seira, Naofumi\|Sanchez, Christopher M\|Regan, John W\|Fujino, Hiromichi\|Murayama, Toshihiko
PMID:	25692008

44.
Journal:	Cancer Prev Res (Phila). 2015 Apr;8(4):303-11.
Title:	Id1 Deficiency Protects against Tumor Formation in Apc(Min/+) Mice but Not in a Mouse Model of Colitis-Associated Colon Cancer.
Author:	Zhang, Ning\|Subbaramaiah, Kotha\|Yantiss, Rhonda K\|Zhou, Xi Kathy\|Chin, Yvette\|Benezra, Robert\|Dannenberg, Andrew J
PMID:	25623217

45.
Journal:	Biol Pharm Bull. 2016;39(2):149-55.
Title:	The Roles of EP4 Prostanoid Receptors in Cancer Malignancy Signaling.
Author:	Fujino, Hiromichi
PMID:	26830476

46.
Journal:	Phytomedicine. 2016 May 15;23(5):558-65.
Title:	Cytotoxic and pro-oxidative effects of Imperata cylindrica aerial part ethyl acetate extract in colorectal cancer in vitro.
Author:	Kwok, Amy Ho Yan\|Wang, Yan\|Ho, Wing Shing
PMID:	27064015

47.
Journal:	Nutr Cancer. 2016 Oct;68(7):1192-201.
Title:	Colonic Saturated Fatty Acid Concentrations and Expression of COX-1, but not Diet, Predict Prostaglandin E2 in Normal Human Colon Tissue.
Author:	Sidahmed, ElKhansa\|Sen, Ananda\|Ren, Jianwei\|Patel, Arsh\|Turgeon, D Kim\|Ruffin, Mack T\|Brenner, Dean E\|Djuric, Zora
PMID:	27548026

48.
Journal:	Gastroenterology. 2017 Feb;152(3):616-630.
Title:	Prostaglandin E2 Activates YAP and a Positive-Signaling Loop to Promote Colon Regeneration After Colitis but Also Carcinogenesis in Mice.
Author:	Kim, Han-Byul\|Kim, Minchul\|Park, Young-Soo\|Park, Intae\|Kim, Tackhoon\|Yang, Sung-Yeun\|Cho, Charles J\|Hwang, DaeHee\|Jung, Jin-Hak\|Markowitz, Sanford D\|Hwang, Sung Wook\|Yang, Suk-Kyun\|Lim, Dae-Sik\|Myung, Seung-Jae
PMID:	27864128

49.
Journal:	World J Gastroenterol. 2017 Feb 21;23(7):1171-1179.
Title:	Thymoquinone suppresses migration of LoVo human colon cancer cells by reducing prostaglandin E2 induced COX-2 activation.
Author:	Hsu, Hsi-Hsien\|Chen, Ming-Cheng\|Day, Cecilia Hsuan\|Lin, Yueh-Min\|Li, Shin-Yi\|Tu, Chuan-Chou\|Padma, Viswanadha Vijaya\|Shih, Hui-Nung\|Kuo, Wei-Wen\|Huang, Chih-Yang
PMID:	28275297

50.
Journal:	Int J Mol Sci. 2017 May 25;18(6). pii: ijms18061132.
Title:	Prostaglandin E2-Induced COX-2 Expressions via EP2 and EP4 Signaling Pathways in Human LoVo Colon Cancer Cells.
Author:	Hsu, Hsi-Hsien\|Lin, Yueh-Min\|Shen, Chia-Yao\|Shibu, Marthandam Asokan\|Li, Shin-Yi\|Chang, Sheng-Huang\|Lin, Chien-Chung\|Chen, Ray-Jade\|Viswanadha, Vijaya Padma\|Shih, Hui-Nung\|Huang, Chih-Yang
PMID:	28587064

51.
Journal:	Cancer Res. 2017 Aug 15;77(16):4305-4316.
Title:	Hypoxia-Induced Downregulation of DUSP-2 Phosphatase Drives Colon Cancer Stemness.
Author:	Hou, Pei-Chi\|Li, Yo-Hua\|Lin, Shih-Chieh\|Lin, Shau-Chieh\|Lee, Jenq-Chang\|Lin, Bo-Wen\|Liou, Jing-Ping\|Chang, Jang-Yang\|Kuo, Ching-Chuan\|Liu, Yi-Min\|Sun, H Sunny\|Tsai, Shaw-Jenq
PMID:	28652251

52.
Journal:	Oncotarget. 2017 Nov 6;8(63):106888-106900.
Title:	Targeting G-protein coupled receptor-related signaling pathway in a murine xenograft model of appendiceal pseudomyxoma peritonei.
Author:	Dilly, Ashok K\|Honick, Brendon D\|Lee, Yong J\|Guo, Zong S\|Zeh, Herbert J\|Bartlett, David L\|Choudry, Haroon A
PMID:	29290997

53.
Journal:	BMB Rep. 2018 Oct;51(10):532-537.
Title:	Cordycepin inhibits lipopolysaccharide-induced cell migration and invasion in human colorectal carcinoma HCT-116 cells through down-regulation of prostaglandin E2 receptor EP4.
Author:	Jeong, Jin-Woo\|Park, Cheol\|Cha, Hee-Jae\|Hong, Su Hyun\|Park, Shin-Hyung\|Kim, Gi-Young\|Kim, Woo Jean\|Kim, Cheol Hong\|Song, Kyoung Seob\|Choi, Yung Hyun
PMID:	30269738