Primary Site >> Colorectal Cancer

Gene >> PTGER1

Journal: Mol Biother. 1992 Dec;4(4):174-83.
Title: Construction and characterization of a high-affinity chimeric anti-colorectal carcinoma antibody ccM4.
Author: Xiang, J|Moyana, T|Kalra, J|Hamilton, T|Qi, Y
PMID: 1476671
Journal: Cancer Biother. 1993 Fall;8(3):253-62.
Title: The tyrosine residue at position 97 in the VH CDR3 region of a mouse/human chimeric anti-colorectal carcinoma antibody contributes hydrogen bonding to the TAG72 antigen.
Author: Xiang, J|Liu, E|Delbaere, L T|Chen, Z|Luo, X|Qi, Y|Rathgeber, C
PMID: 7804366
Journal: Hum Antibodies Hybridomas. 1994;5(3-4):105-15.
Title: Recombinant mouse/human chimeric anti-colorectal carcinoma antibody cACT19.
Author: Xiang, J|Moyana, T|Liu, E
PMID: 7756575
Journal: Cancer Res. 1999 Oct 15;59(20):5093-6.
Title: Role of the prostaglandin E receptor subtype EP1 in colon carcinogenesis.
Author: Watanabe, K|Kawamori, T|Nakatsugi, S|Ohta, T|Ohuchida, S|Yamamoto, H|Maruyama, T|Kondo, K|Ushikubi, F|Narumiya, S|Sugimura, T|Wakabayashi, K
PMID: 10537280
Journal: Cancer Lett. 2000 May 1;152(2):217-22.
Title: Effect of prostaglandin E(2) on the proliferation, Ca(2+) mobilization and cAMP in HT-29 human colon adenocarcinoma cells.
Author: Cassano, G|Gasparre, G|Susca, F|Lippe, C|Guanti, G
PMID: 10773415
Journal: Biofactors. 2000;12(1-4):129-33.
Title: COX-2 and iNOS, good targets for chemoprevention of colon cancer.
Author: Watanabe, K|Kawamori, T|Nakatsugi, S|Wakabayashi, K
PMID: 11216473
Journal: Nat Med. 2001 Sep;7(9):1048-51.
Title: Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc(Delta 716) knockout mice.
Author: Sonoshita, M|Takaku, K|Sasaki, N|Sugimoto, Y|Ushikubi, F|Narumiya, S|Oshima, M|Taketo, M M
PMID: 11533709
Journal: Anticancer Res. 2001 Nov-Dec;21(6A):3865-9.
Title: Evaluation of a selective prostaglandin E receptor EP1 antagonist for potential properties in colon carcinogenesis.
Author: Kawamori, T|Uchiya, N|Kitamura, T|Ohuchida, S|Yamamoto, H|Maruyama, T|Sugimura, T|Wakabayashi, K
PMID: 11911260
Journal: J Environ Pathol Toxicol Oncol. 2002;21(2):149-53.
Title: COX-2 and prostanoid receptors: good targets for chemoprevention.
Author: Kawamori, Toshihiko|Wakabayashi, Keiji
PMID: 12086401
Journal: Cancer Sci. 2005 May;96(5):260-4.
Title: Suppression of azoxymethane-induced colon cancer development in rats by a prostaglandin E receptor EP1-selective antagonist.
Author: Niho, Naoko|Mutoh, Michihiro|Kitamura, Tomohiro|Takahashi, Mami|Sato, Hidetaka|Yamamoto, Hiroshi|Maruyama, Takayuki|Ohuchida, Shuichi|Sugimura, Takashi|Wakabayashi, Keiji
PMID: 15904466
Journal: Biochem Soc Trans. 2005 Aug;33(Pt 4):667-71.
Title: Prospects in NSAID-derived chemoprevention of colorectal cancer.
Author: Chell, S|Patsos, H A|Qualtrough, D|H-Zadeh, A M|Hicks, D J|Kaidi, A|Witherden, I R|Williams, A C|Paraskeva, C
PMID: 16042570
Journal: World J Gastroenterol. 2005 Jan 21;11(3):344-7.
Title: Expression pattern of epithelial cell adhesion molecule on normal and malignant colon tissues.
Author: Xie, Xin|Wang, Chun-Yan|Cao, Yun-Xin|Wang, Wei|Zhuang, Ran|Chen, Li-Hua|Dang, Na-Na|Fang, Liang|Jin, Bo-Quan
PMID: 15637741
Journal: Curr Pharm Des. 2006;12(19):2375-82.
Title: Roles of prostanoids in colon carcinogenesis and their potential targeting for cancer chemoprevention.
Author: Mutoh, Michihiro|Takahashi, Mami|Wakabayashi, Keiji
PMID: 16842185
Journal: Biochim Biophys Acta. 2006 Aug;1766(1):104-19. Epub 2006 May 23.
Title: Mediators of PGE2 synthesis and signalling downstream of COX-2 represent potential targets for the prevention/treatment of colorectal cancer.
Author: Chell, Simon|Kaidi, Abderrahmane|Williams, Ann Caroline|Paraskeva, Christos
PMID: 16859832
Journal: Int J Cancer. 2007 Jul 15;121(2):232-40.
Title: EP1-4 subtype, COX and PPAR gamma receptor expression in colorectal cancer in prediction of disease-specific mortality.
Author: Gustafsson, Annika|Hansson, Elisabeth|Kressner, Ulf|Nordgren, Svante|Andersson, Marianne|Wang, Wenhua|Lonnroth, Christina|Lundholm, Kent
PMID: 17290397
Journal: Biochem Biophys Res Commun. 2007 Aug 3;359(3):568-73.
Title: Indomethacin decreases EP2 prostanoid receptor expression in colon cancer cells.
Author: Fujino, Hiromichi|Chen, Xiao-bo|Regan, John W|Murayama, Toshihiko
PMID: 17555711
Journal: Exp Cell Res. 2007 Aug 15;313(14):2969-79.
Title: The EP4 receptor antagonist, L-161,982, blocks prostaglandin E2-induced signal transduction and cell proliferation in HCA-7 colon cancer cells.
Author: Cherukuri, Durga Prasad|Chen, Xiao B O|Goulet, Anne-Christine|Young, Robert N|Han, Yongxin|Heimark, Ronald L|Regan, John W|Meuillet, Emmanuelle|Nelson, Mark A
PMID: 17631291
Journal: BMC Cell Biol. 2008 Dec 2;9:63.
Title: Prostaglandin E2-EP1 and EP2 receptor signaling promotes apical junctional complex disassembly of Caco-2 human colorectal cancer cells.
Author: Tanaka, Marcelo N|Diaz, Bruno L|de Souza, Wanderley|Morgado-Diaz, Jose A
PMID: 19055708
Journal: Biochem Biophys Res Commun. 2008 Jul 18;372(1):249-53.
Title: Genetic deletion of mPGES-1 accelerates intestinal tumorigenesis in APC(Min/+) mice.
Author: Elander, N|Ungerback, J|Olsson, H|Uematsu, S|Akira, S|Soderkvist, P
PMID: 18485889
Journal: Mod Pathol. 2008 Jan;21(1):15-21.
Title: Prostanoid receptor EP1 expression in breast cancer.
Author: Thorat, Mangesh A|Morimiya, Akira|Mehrotra, Sanjana|Konger, Raymond|Badve, Sunil S
PMID: 17906615
Journal: Br J Cancer. 2008 Aug 5;99(3):502-12.
Title: Prostaglandin E2 stimulates Fas ligand expression via the EP1 receptor in colon cancer cells.
Author: O'Callaghan, G|Kelly, J|Shanahan, F|Houston, A
PMID: 18648368
Journal: Int J Oncol. 2010 Feb;36(2):469-78.
Title: Receptor and enzyme expression for prostanoid metabolism in colorectal cancer related to tumor tissue PGE2.
Author: Gustafsson, Annika|Andersson, Marianne|Lagerstedt, Kristina|Lonnroth, Christina|Nordgren, Svante|Lundholm, Kent
PMID: 20043083
Journal: BMC Gastroenterol. 2010 Jan 26;10:9.
Title: Prostaglandin E2-induced colonic secretion in patients with and without colorectal neoplasia.
Author: Kaltoft, Nicolai|Tilotta, Maria C|Witte, Anne-Barbara|Osbak, Philip S|Poulsen, Steen S|Bindslev, Niels|Hansen, Mark B
PMID: 20100359
Journal: Arch Toxicol. 2010 Sep;84(9):731-40.
Title: EP4 upregulation of Ras signaling and feedback regulation of Ras in human colon tissues and cancer cells.
Author: Wu, Cheng-Hsun|Shih, Yuan-Wei|Chang, Chun-Hua|Ou, Ting-Tsz|Huang, Chi-Chou|Hsu, Jeng-Dong|Wang, Chau-Jong
PMID: 20571779
Journal: Cancer Biol Ther. 2010 Nov 15;10(10):1056-66.
Title: The induction of S100p expression by the Prostaglandin E(2) (PGE(2))/EP4 receptor signaling pathway in colon cancer cells.
Author: Chandramouli, Anupama|Mercado-Pimentel, Melania E|Hutchinson, Anthony|Gibadulinova, Adriana|Olson, Erik R|Dickinson, Sally|Shanas, Renee|Davenport, Jennifer|Owens, Janae|Bhattacharyya, Achyut K|Regan, John W|Pastorekova, Silvia|Arumugam, Thiruvengadam|Log
PMID: 20890108
Journal: Cancer Res. 2011 Nov 15;71(22):7010-20.
Title: ANGPTL4 induction by prostaglandin E2 under hypoxic conditions promotes colorectal cancer progression.
Author: Kim, Sun-Hee|Park, Yun-Yong|Kim, Sang-Wook|Lee, Ju-Seog|Wang, Dingzhi|DuBois, Raymond N
PMID: 21937683
Journal: Int J Cancer. 2013 Aug 15;133(4):825-34.
Title: Targeting the EP1 receptor reduces Fas ligand expression and increases the antitumor immune response in an in vivo model of colon cancer.
Author: O'Callaghan, Grace|Ryan, Aideen|Neary, Peter|O'Mahony, Caitlin|Shanahan, Fergus|Houston, Aileen
PMID: 23390011
Journal: Transl Res. 2013 Aug;162(2):77-92.
Title: Cyclooxygenase-2-prostaglandin E2-eicosanoid receptor inflammatory axis: a key player in Kaposi's sarcoma-associated herpes virus associated malignancies.
Author: Paul, Arun George|Chandran, Bala|Sharma-Walia, Neelam
PMID: 23567332
Journal: Free Radic Res. 2014 Nov;48(11):1311-21.
Title: Generation of ROS by CAY10598 leads to inactivation of STAT3 signaling and induction of apoptosis in human colon cancer HCT116 cells.
Author: Chae, I G|Kim, D-H|Kundu, J|Jeong, C-H|Kundu, J K|Chun, K-S
PMID: 25096910
Journal: Life Sci. 2014 Oct 22;116(1):43-50.
Title: Prostaglandin E2 produced by inducible COX-2 and mPGES-1 promoting cancer cell proliferation in vitro and in vivo.
Author: Ruan, Diana|So, Shui-Ping
PMID: 25139833
Journal: Cancer Res. 2015 Jul 15;75(14):2822-32.
Title: Definition of Prostaglandin E2-EP2 Signals in the Colon Tumor Microenvironment That Amplify Inflammation and Tumor Growth.
Author: Ma, Xiaojun|Aoki, Tomohiro|Tsuruyama, Tatsuaki|Narumiya, Shuh
PMID: 26018088
Journal: Am J Cancer Res. 2015 May 15;5(6):2012-21. eCollection 2015.
Title: Cyclooxygenase-2 knockdown using retinoic acid chalcone (RAC), a promising therapeutic strategy for colon cancer.
Author: Jiang, Chao|Wang, Qiong|Xu, Zhe|Li, Wei-Su|Chen, Che|Yao, Xue-Quan|Liu, Fu-Kun
PMID: 26269760
Journal: Tumour Biol. 2016 Jan;37(1):323-9.
Title: Retinoic acid morpholine amide (RAMA) inhibits expression of Fas ligand through EP1 receptor in colon cancer cells.
Author: Chen, Shao-Xuan|Du, Shi-Yu|Wang, Yun-Ting|Zhao, Hong-Chuan|Zhang, Yan-Li|Yao, Li
PMID: 26211005
Journal: Oncogene. 2016 May 19;35(20):2602-14.
Title: Dysregulated CRTC1 activity is a novel component of PGE2 signaling that contributes to colon cancer growth.
Author: Schumacher, Y|Aparicio, T|Ourabah, S|Baraille, F|Martin, A|Wind, P|Dentin, R|Postic, C|Guilmeau, S
PMID: 26300003
Journal: Biol Pharm Bull. 2016;39(2):149-55.
Title: The Roles of EP4 Prostanoid Receptors in Cancer Malignancy Signaling.
Author: Fujino, Hiromichi
PMID: 26830476
Journal: Phytomedicine. 2016 May 15;23(5):558-65.
Title: Cytotoxic and pro-oxidative effects of Imperata cylindrica aerial part ethyl acetate extract in colorectal cancer in vitro.
Author: Kwok, Amy Ho Yan|Wang, Yan|Ho, Wing Shing
PMID: 27064015
Journal: IUBMB Life. 2017 Dec;69(12):956-961.
Title: High HSF4 expression is an independent indicator of poor overall survival and recurrence free survival in patients with primary colorectal cancer.
Author: Yang, Yingchi|Jin, Lan|Zhang, Jinghui|Wang, Jin|Zhao, Xiaomu|Wu, Guocong|Yao, Hongwei|Zhang, Zhongtao
PMID: 29131521