Primary Site >> Colorectal Cancer
Gene >> PTGER1
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Ref: Construction and characterization of a high-affinity chimeric anti-colorectal carcinoma antibody ccM4. PMID: 1476671 |
Ref: The tyrosine residue at position 97 in the VH CDR3 region of a mouse/human chimeric anti-colorectal carcinoma antibody contributes hydrogen bonding to the TAG72 antigen. PMID: 7804366 |
Ref: Recombinant mouse/human chimeric anti-colorectal carcinoma antibody cACT19. PMID: 7756575 |
Ref: Role of the prostaglandin E receptor subtype EP1 in colon carcinogenesis. PMID: 10537280 |
Ref: Effect of prostaglandin E(2) on the proliferation, Ca(2+) mobilization and cAMP in HT-29 human colon adenocarcinoma cells. PMID: 10773415 Ref: COX-2 and iNOS, good targets for chemoprevention of colon cancer. PMID: 11216473 |
Ref: Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc(Delta 716) knockout mice. PMID: 11533709 Ref: Evaluation of a selective prostaglandin E receptor EP1 antagonist for potential properties in colon carcinogenesis. PMID: 11911260 |
Ref: COX-2 and prostanoid receptors: good targets for chemoprevention. PMID: 12086401 |
Ref: Expression pattern of epithelial cell adhesion molecule on normal and malignant colon tissues. PMID: 15637741 Ref: Suppression of azoxymethane-induced colon cancer development in rats by a prostaglandin E receptor EP1-selective antagonist. PMID: 15904466 Ref: Prospects in NSAID-derived chemoprevention of colorectal cancer. PMID: 16042570 |
Ref: Roles of prostanoids in colon carcinogenesis and their potential targeting for cancer chemoprevention. PMID: 16842185 Ref: Mediators of PGE2 synthesis and signalling downstream of COX-2 represent potential targets for the prevention/treatment of colorectal cancer. PMID: 16859832 |
Ref: EP1-4 subtype, COX and PPAR gamma receptor expression in colorectal cancer in prediction of disease-specific mortality. PMID: 17290397 Ref: Indomethacin decreases EP2 prostanoid receptor expression in colon cancer cells. PMID: 17555711 Ref: The EP4 receptor antagonist, L-161,982, blocks prostaglandin E2-induced signal transduction and cell proliferation in HCA-7 colon cancer cells. PMID: 17631291 |
Ref: Prostanoid receptor EP1 expression in breast cancer. PMID: 17906615 Ref: Genetic deletion of mPGES-1 accelerates intestinal tumorigenesis in APC(Min/+) mice. PMID: 18485889 Ref: Prostaglandin E2 stimulates Fas ligand expression via the EP1 receptor in colon cancer cells. PMID: 18648368 Ref: Prostaglandin E2-EP1 and EP2 receptor signaling promotes apical junctional complex disassembly of Caco-2 human colorectal cancer cells. PMID: 19055708 |
Ref: Receptor and enzyme expression for prostanoid metabolism in colorectal cancer related to tumor tissue PGE2. PMID: 20043083 Ref: Prostaglandin E2-induced colonic secretion in patients with and without colorectal neoplasia. PMID: 20100359 Ref: EP4 upregulation of Ras signaling and feedback regulation of Ras in human colon tissues and cancer cells. PMID: 20571779 Ref: The induction of S100p expression by the Prostaglandin E(2) (PGE(2))/EP4 receptor signaling pathway in colon cancer cells. PMID: 20890108 |
Ref: ANGPTL4 induction by prostaglandin E2 under hypoxic conditions promotes colorectal cancer progression. PMID: 21937683 |
Ref: Targeting the EP1 receptor reduces Fas ligand expression and increases the antitumor immune response in an in vivo model of colon cancer. PMID: 23390011 Ref: Cyclooxygenase-2-prostaglandin E2-eicosanoid receptor inflammatory axis: a key player in Kaposi's sarcoma-associated herpes virus associated malignancies. PMID: 23567332 |
Ref: Generation of ROS by CAY10598 leads to inactivation of STAT3 signaling and induction of apoptosis in human colon cancer HCT116 cells. PMID: 25096910 Ref: Prostaglandin E2 produced by inducible COX-2 and mPGES-1 promoting cancer cell proliferation in vitro and in vivo. PMID: 25139833 |
Ref: Definition of Prostaglandin E2-EP2 Signals in the Colon Tumor Microenvironment That Amplify Inflammation and Tumor Growth. PMID: 26018088 Ref: Cyclooxygenase-2 knockdown using retinoic acid chalcone (RAC), a promising therapeutic strategy for colon cancer. PMID: 26269760 |
Ref: Retinoic acid morpholine amide (RAMA) inhibits expression of Fas ligand through EP1 receptor in colon cancer cells. PMID: 26211005 Ref: Dysregulated CRTC1 activity is a novel component of PGE2 signaling that contributes to colon cancer growth. PMID: 26300003 Ref: The Roles of EP4 Prostanoid Receptors in Cancer Malignancy Signaling. PMID: 26830476 Ref: Cytotoxic and pro-oxidative effects of Imperata cylindrica aerial part ethyl acetate extract in colorectal cancer in vitro. PMID: 27064015 |
Ref: High HSF4 expression is an independent indicator of poor overall survival and recurrence free survival in patients with primary colorectal cancer. PMID: 29131521 |