Primary Site >> Pancreatic Cancer
Gene >> PTF1A
| 1. | |||||||||||
| Journal: | Pancreas. 1986;1(1):49-54. | ||||||||||
| Title: | Combined effects of alpha-difluoromethylornithine and doxorubicin against pancreatic cancer cell lines in culture. | ||||||||||
| Author: | Chang, B K|Gutman, R|Black, O Jr | ||||||||||
| PMID: | 3106959 | ||||||||||
| 2. | |||||||||||
| Journal: | Gastroenterology. 2004 Sep;127(3):937-49. | ||||||||||
| Title: | PTF1alpha/p48 transcription factor couples proliferation and differentiation in the exocrine pancreas [corrected]. | ||||||||||
| Author: | Rodolosse, Annie|Chalaux, Elisabet|Adell, Teresa|Hagege, Helene|Skoudy, Anouchka|Real, Francisco X | ||||||||||
| PMID: | 15362048 | ||||||||||
| 3. | |||||||||||
| Journal: | Methods Enzymol. 2008;438:391-417. | ||||||||||
| Title: | Characterization of Kras-mediated pancreatic tumorigenesis in zebrafish. | ||||||||||
| Author: | Davison, Jon M|Woo Park, Seung|Rhee, Jerry M|Leach, Steven D | ||||||||||
| PMID: | 18413263 | ||||||||||
| 4. | |||||||||||
| Journal: | Gastroenterology. 2008 Jun;134(7):2080-90. | ||||||||||
| Title: | Oncogenic KRAS induces progenitor cell expansion and malignant transformation in zebrafish exocrine pancreas. | ||||||||||
| Author: | Park, Seung Woo|Davison, Jon M|Rhee, Jerry|Hruban, Ralph H|Maitra, Anirban|Leach, Steven D | ||||||||||
| PMID: | 18549880 | ||||||||||
| 5. | |||||||||||
| Journal: | Gastroenterology. 2008 Oct;135(4):1301-1310, 1310.e1-5. | ||||||||||
| Title: | Murine embryonic stem cell-derived pancreatic acinar cells recapitulate features of early pancreatic differentiation. | ||||||||||
| Author: | Rovira, Meritxell|Delaspre, Fabien|Massumi, Mohammad|Serra, Selma A|Valverde, Miguel Angel|Lloreta, Josep|Dufresne, Marlene|Payre, Bruno|Konieczny, Stephen F|Savatier, Pierre|Real, Francisco X|Skoudy, Anouchka | ||||||||||
| PMID: | 18725222 | ||||||||||
| 6. | |||||||||||
| Journal: | Int J Cancer. 2011 Jul 15;129(2):295-306. | ||||||||||
| Title: | Id3 modulates cellular localization of bHLH Ptf1-p48 protein. | ||||||||||
| Author: | Dufresne, Marlene|Clerc, Pascal|Dieng, Madieng|Edir, Anissa|Couvelard, Anne|Delisle, Marie-Bernadette|Fourmy, Daniel|Gigoux, Veronique | ||||||||||
| PMID: | 20830706 | ||||||||||
| 7. | |||||||||||
| Journal: | PLoS One. 2011;6(12):e27941. | ||||||||||
| Title: | Aberrant Hedgehog ligands induce progressive pancreatic fibrosis by paracrine activation of myofibroblasts and ductular cells in transgenic zebrafish. | ||||||||||
| Author: | Jung, In Hye|Jung, Dawoon E|Park, Young Nyun|Song, Si Young|Park, Seung Woo | ||||||||||
| PMID: | 22164219 | ||||||||||
| 8. | |||||||||||
| Journal: | Cancer Sci. 2013 Mar;104(3):337-44. | ||||||||||
| Title: | Therapeutic effect of c-Jun N-terminal kinase inhibition on pancreatic cancer. | ||||||||||
| Author: | Takahashi, Ryota|Hirata, Yoshihiro|Sakitani, Kosuke|Nakata, Wachiko|Kinoshita, Hiroto|Hayakawa, Yoku|Nakagawa, Hayato|Sakamoto, Kei|Hikiba, Yohko|Ijichi, Hideaki|Moses, Harold L|Maeda, Shin|Koike, Kazuhiko | ||||||||||
| PMID: | 23237571 | ||||||||||
| 9. | |||||||||||
| Journal: | PLoS One. 2013;8(1):e54243. | ||||||||||
| Title: | Directed pancreatic acinar differentiation of mouse embryonic stem cells via embryonic signalling molecules and exocrine transcription factors. | ||||||||||
| Author: | Delaspre, Fabien|Massumi, Mohammad|Salido, Marta|Soria, Bernat|Ravassard, Philippe|Savatier, Pierre|Skoudy, Anouchka | ||||||||||
| PMID: | 23349836 | ||||||||||
| 10. | |||||||||||
| Journal: | Gastroenterology. 2014 Jan;146(1):257-67. | ||||||||||
| Title: | Activated wnt signaling in stroma contributes to development of pancreatic mucinous cystic neoplasms. | ||||||||||
| Author: | Sano, Makoto|Driscoll, David R|De Jesus-Monge, Wilfredo E|Klimstra, David S|Lewis, Brian C | ||||||||||
| PMID: | 24067880 | ||||||||||
| 11. | |||||||||||
| Journal: | Zebrafish. 2014 Dec;11(6):551-9. | ||||||||||
| Title: | The tumor suppressor rpl36 restrains KRAS(G12V)-induced pancreatic cancer. | ||||||||||
| Author: | Provost, Elayne|Bailey, Jennifer M|Aldrugh, Sumar|Liu, Shu|Iacobuzio-Donahue, Christine|Leach, Steven D | ||||||||||
| PMID: | 25380065 | ||||||||||
| 12. | |||||||||||
| Journal: | Gastroenterology. 2014 Dec;147(6):1405-16.e7. | ||||||||||
| Title: | PI3K regulation of RAC1 is required for KRAS-induced pancreatic tumorigenesis in mice. | ||||||||||
| Author: | Wu, Chia-Yen C|Carpenter, Eileen S|Takeuchi, Kenneth K|Halbrook, Christopher J|Peverley, Louise V|Bien, Harold|Hall, Jason C|DelGiorno, Kathleen E|Pal, Debjani|Song, Yan|Shi, Chanjuan|Lin, Richard Z|Crawford, Howard C | ||||||||||
| PMID: | 25311989 | ||||||||||
| 13. | |||||||||||
| Journal: | J Nucl Med. 2014 Mar;55(3):446-51. | ||||||||||
| Title: | Multimodal molecular imaging of integrin alphavbeta3 for in vivo detection of pancreatic cancer. | ||||||||||
| Author: | Trajkovic-Arsic, Marija|Mohajerani, Pouyan|Sarantopoulos, Athanasios|Kalideris, Evdokia|Steiger, Katja|Esposito, Irene|Ma, Xiaopeng|Themelis, George|Burton, Neal|Michalski, Christoph W|Kleeff, Jorg|Stangl, Stefan|Beer, Ambros J|Pohle, Karolin|Wester, Hans | ||||||||||
| PMID: | 24549287 | ||||||||||
| 14. | |||||||||||
| Journal: | Gastroenterology. 2014 Jan;146(1):233-44.e5. | ||||||||||
| Title: | Identification and manipulation of biliary metaplasia in pancreatic tumors. | ||||||||||
| Author: | Delgiorno, Kathleen E|Hall, Jason C|Takeuchi, Kenneth K|Pan, Fong Cheng|Halbrook, Christopher J|Washington, M Kay|Olive, Kenneth P|Spence, Jason R|Sipos, Bence|Wright, Christopher V E|Wells, James M|Crawford, Howard C | ||||||||||
| PMID: | 23999170 | ||||||||||
| 15. | |||||||||||
| Journal: | Gut. 2014 Apr;63(4):647-55. | ||||||||||
| Title: | Nr5a2 heterozygosity sensitises to, and cooperates with, inflammation in KRas(G12V)-driven pancreatic tumourigenesis. | ||||||||||
| Author: | Flandez, Marta|Cendrowski, Jaroslaw|Canamero, Marta|Salas, Antonio|del Pozo, Natalia|Schoonjans, Kristina|Real, Francisco X | ||||||||||
| PMID: | 23598351 | ||||||||||
| 16. | |||||||||||
| Journal: | Oncogene. 2015 May 21;34(21):2801-6. | ||||||||||
| Title: | Differential in vivo tumorigenicity of diverse KRAS mutations in vertebrate pancreas: A comprehensive survey. | ||||||||||
| Author: | Park, J T|Johnson, N|Liu, S|Levesque, M|Wang, Y J|Ho, H|Huso, D|Maitra, A|Parsons, M J|Prescott, J D|Leach, S D | ||||||||||
| PMID: | 25065594 | ||||||||||
| 17. | |||||||||||
| Journal: | Tumour Biol. 2015 May;36(5):3245-9. | ||||||||||
| Title: | Inhibition of progression of PanIN through antagonizing EGFR. | ||||||||||
| Author: | He, Xiaojun|Zhang, Hui|Xiao, Mei|Kong, Yalin|Li, Wenbing|Zhang, Hongyi | ||||||||||
| PMID: | 25519686 | ||||||||||
| 18. | |||||||||||
| Journal: | Elife. 2015 Jul 7;4. | ||||||||||
| Title: | The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma. | ||||||||||
| Author: | Krah, Nathan M|De La O, Jean-Paul|Swift, Galvin H|Hoang, Chinh Q|Willet, Spencer G|Chen Pan, Fong|Cash, Gabriela M|Bronner, Mary P|Wright, Christopher Ve|MacDonald, Raymond J|Murtaugh, L Charles | ||||||||||
| PMID: | 26151762 | ||||||||||
| 19. | |||||||||||
| Journal: | Gastroenterology. 2015 Dec;149(7):1932-1943.e9. | ||||||||||
| Title: | Signal Transducer and Activator of Transcription 3, Mediated Remodeling of the Tumor Microenvironment Results in Enhanced Tumor Drug Delivery in a Mouse Model of Pancreatic Cancer. | ||||||||||
| Author: | Nagathihalli, Nagaraj S|Castellanos, Jason A|Shi, Chanjuan|Beesetty, Yugandhar|Reyzer, Michelle L|Caprioli, Richard|Chen, Xi|Walsh, Alex J|Skala, Melissa C|Moses, Harold L|Merchant, Nipun B | ||||||||||
| PMID: | 26255562 | ||||||||||
| 20. | |||||||||||
| Journal: | Gut. 2016 Jun;65(6):1001-14. | ||||||||||
| Title: | Activated Schwann cells in pancreatic cancer are linked to analgesia via suppression of spinal astroglia and microglia. | ||||||||||
| Author: | Demir, Ihsan Ekin|Tieftrunk, Elke|Schorn, Stephan|Saricaoglu, Omer Cemil|Pfitzinger, Paulo L|Teller, Steffen|Wang, Kun|Waldbaur, Christine|Kurkowski, Magdalena U|Wormann, Sonja Maria|Shaw, Victoria E|Kehl, Timo|Laschinger, Melanie|Costello, Eithne|Algul, | ||||||||||
| PMID: | 26762195 | ||||||||||
| 21. | |||||||||||
| Journal: | Neoplasia. 2016 Dec;18(12):785-794. | ||||||||||
| Title: | Activation of WNT/beta-Catenin Signaling Enhances Pancreatic Cancer Development and the Malignant Potential Via Up-regulation of Cyr61. | ||||||||||
| Author: | Sano, Makoto|Driscoll, David R|DeJesus-Monge, Wilfredo E|Quattrochi, Brian|Appleman, Victoria A|Ou, Jianhong|Zhu, Lihua Julie|Yoshida, Nao|Yamazaki, Shintaro|Takayama, Tadatoshi|Sugitani, Masahiko|Nemoto, Norimichi|Klimstra, David S|Lewis, Brian C | ||||||||||
| PMID: | 27889647 | ||||||||||
| 22. | |||||||||||
| Journal: | Dokl Biochem Biophys. 2016 Jul;469(1):257-9. | ||||||||||
| Title: | Downregulation of expression of mater genes SOX9, FOXA2, and GATA4 in pancreatic cancer cells stimulated with TGFbeta1 epithelial-mesenchymal transition. | ||||||||||
| Author: | Kondratyeva, L G|Sveshnikova, A A|Grankina, E V|Chernov, I P|Kopantseva, M R|Kopantzev, E P|Sverdlov, E D | ||||||||||
| PMID: | 27599506 | ||||||||||
| 23. | |||||||||||
| Journal: | J Pathol. 2016 Feb;238(3):434-45. | ||||||||||
| Title: | Inactivation of TGFbeta receptor II signalling in pancreatic epithelial cells promotes acinar cell proliferation, acinar-to-ductal metaplasia and fibrosis during pancreatitis. | ||||||||||
| Author: | Grabliauskaite, Kamile|Saponara, Enrica|Reding, Theresia|Bombardo, Marta|Seleznik, Gitta M|Malagola, Ermanno|Zabel, Anja|Faso, Carmen|Sonda, Sabrina|Graf, Rolf | ||||||||||
| PMID: | 26510396 | ||||||||||
| 24. | |||||||||||
| Journal: | Gastroenterology. 2016 Nov;151(5):1011-1024.e7. | ||||||||||
| Title: | Pancreatic Premalignant Lesions Secrete Tissue Inhibitor of Metalloproteinases-1, Which Activates Hepatic Stellate Cells Via CD63 Signaling to Create a Premetastatic Niche in the Liver. | ||||||||||
| Author: | Grunwald, Barbara|Harant, Veronika|Schaten, Susanne|Fruhschutz, Monika|Spallek, Ria|Hochst, Bastian|Stutzer, Katharina|Berchtold, Sonja|Erkan, Mert|Prokopchuk, Olga|Martignoni, Marc|Esposito, Irene|Heikenwalder, Mathias|Gupta, Aayush|Siveke, Jens|Saftig, | ||||||||||
| PMID: | 27506299 | ||||||||||
| 25. | |||||||||||
| Journal: | Mol Carcinog. 2017 Mar;56(3):936-944. | ||||||||||
| Title: | The TALE homeodomain transcription factor MEIS1 activates the pro-metastatic melanoma cell adhesion molecule Mcam to promote migration of pancreatic cancer cells. | ||||||||||
| Author: | von Burstin, Johannes|Bachhuber, Friedrich|Paul, Mariel|Schmid, Roland M|Rustgi, Anil K | ||||||||||
| PMID: | 27583552 | ||||||||||
| 26. | |||||||||||
| Journal: | Clin Cancer Res. 2017 Mar 15;23(6):1607-1620. | ||||||||||
| Title: | Mutant p53 Together with TGFbeta Signaling Influence Organ-Specific Hematogenous Colonization Patterns of Pancreatic Cancer. | ||||||||||
| Author: | Zhong, Yi|Macgregor-Das, Anne|Saunders, Tyler|Whittle, Martin C|Makohon-Moore, Alvin|Kohutek, Zachary A|Poling, Justin|Herbst, Brian T|Javier, Breanna M|Cope, Leslie|Leach, Steven D|Hingorani, Sunil R|Iacobuzio-Donahue, Christine A | ||||||||||
| PMID: | 27637888 | ||||||||||
| 27. | |||||||||||
| Journal: | PLoS One. 2017 May 5;12(5):e0176844. | ||||||||||
| Title: | LSL-KrasG12D; LSL-Trp53R172H/+; Ink4flox/+; Ptf1/p48-Cre mice are an applicable model for locally invasive and metastatic pancreatic cancer. | ||||||||||
| Author: | Ma, Lixiang|Saiyin, Hexige | ||||||||||
| PMID: | 28475592 | ||||||||||
| 28. | |||||||||||
| Journal: | Br J Cancer. 2017 Aug 22;117(5):639-647. | ||||||||||
| Title: | HMGA1 expression levels are elevated in pancreatic intraepithelial neoplasia cells in the Ptf1a-Cre; LSL-KrasG12D transgenic mouse model of pancreatic cancer. | ||||||||||
| Author: | Veite-Schmahl, Michelle J|Joesten, William C|Kennedy, Michael A | ||||||||||
| PMID: | 28697176 | ||||||||||
| 29. | |||||||||||
| Journal: | Cancer Sci. 2017 Nov;108(11):2156-2165. | ||||||||||
| Title: | c-Jun N-terminal kinase in pancreatic tumor stroma augments tumor development in mice. | ||||||||||
| Author: | Sato, Takeshi|Shibata, Wataru|Hikiba, Yohko|Kaneta, Yoshihiro|Suzuki, Nobumi|Ihara, Sozaburo|Ishii, Yasuaki|Sue, Soichiro|Kameta, Eri|Sugimori, Makoto|Yamada, Hiroaki|Kaneko, Hiroaki|Sasaki, Tomohiko|Ishii, Tomohiro|Tamura, Toshihide|Kondo, Masaaki|Maeda, | ||||||||||
| PMID: | 28837246 | ||||||||||
| 30. | |||||||||||
| Journal: | Dokl Biochem Biophys. 2017 Jul;475(1):250-252. | ||||||||||
| Title: | Expression of master regulatory genes of embryonic development in pancreatic tumors. | ||||||||||
| Author: | Kondratyeva, L G|Chernov, I P|Zinovyeva, M V|Kopantzev, E P|Sverdlov, E D | ||||||||||
| PMID: | 28864900 | ||||||||||
| 31. | |||||||||||
| Journal: | J Vis Exp. 2017 Aug 19;(126). | ||||||||||
| Title: | Dissection of the Mouse Pancreas for Histological Analysis and Metabolic Profiling. | ||||||||||
| Author: | Veite-Schmahl, Michelle J|Regan, Daniel P|Rivers, Adam C|Nowatzke, Joseph F|Kennedy, Michael A | ||||||||||
| PMID: | 28872120 | ||||||||||
| 32. | |||||||||||
| Journal: | Sci Rep. 2018 Sep 21;8(1):14211. | ||||||||||
| Title: | Chemotherapy payload of anti-insoluble fibrin antibody-drug conjugate is released specifically upon binding to fibrin. | ||||||||||
| Author: | Fuchigami, Hirobumi|Manabe, Shino|Yasunaga, Masahiro|Matsumura, Yasuhiro | ||||||||||
| PMID: | 30242282 | ||||||||||
| 33. | |||||||||||
| Journal: | Hum Pathol. 2018 Aug 18. pii: S0046-8177(18)30315-0. | ||||||||||
| Title: | Solid-pseudopapillary neoplasms of the pancreas do not express major pancreatic markers in pediatric patients. | ||||||||||
| Author: | Calvani, Julien|Lopez, Pauline|Sarnacki, Sabine|Molina, Thierry Jo|Gibault, Laure|Fabre, Monique|Scharfmann, Raphael|Capito, Carmen|Galmiche, Louise | ||||||||||
| PMID: | 30130629 | ||||||||||
| 34. | |||||||||||
| Journal: | PLoS One. 2018 Jul 17;13(7):e0200658. | ||||||||||
| Title: | NMR-based metabolic profiling of urine, serum, fecal, and pancreatic tissue samples from the Ptf1a-Cre; LSL-KrasG12D transgenic mouse model of pancreatic cancer. | ||||||||||
| Author: | Schmahl, Michelle J|Regan, Daniel P|Rivers, Adam C|Joesten, William C|Kennedy, Michael A | ||||||||||
| PMID: | 30016349 | ||||||||||
| 35. | |||||||||||
| Journal: | J Clin Invest. 2018 Aug 1;128(8):3475-3489. | ||||||||||
| Title: | The BRG1/SOX9 axis is critical for acinar cell-derived pancreatic tumorigenesis. | ||||||||||
| Author: | Tsuda, Motoyuki|Fukuda, Akihisa|Roy, Nilotpal|Hiramatsu, Yukiko|Leonhardt, Laura|Kakiuchi, Nobuyuki|Hoyer, Kaja|Ogawa, Satoshi|Goto, Norihiro|Ikuta, Kozo|Kimura, Yoshito|Matsumoto, Yoshihide|Takada, Yutaka|Yoshioka, Takuto|Maruno, Takahisa|Yamaga, Yuichi| | ||||||||||
| PMID: | 30010625 | ||||||||||
| 36. | |||||||||||
| Journal: | Mol Oncol. 2018 Jun;12(7):1104-1124. | ||||||||||
| Title: | Induced PTF1a expression in pancreatic ductal adenocarcinoma cells activates acinar gene networks, reduces tumorigenic properties, and sensitizes cells to gemcitabine treatment. | ||||||||||
| Author: | Jakubison, Brad L|Schweickert, Patrick G|Moser, Sarah E|Yang, Yi|Gao, Hongyu|Scully, Kathleen|Itkin-Ansari, Pamela|Liu, Yunlong|Konieczny, Stephen F | ||||||||||
| PMID: | 29719936 | ||||||||||
| 37. | |||||||||||
| Journal: | Pancreatology. 2018 Mar;18(2):184-190. | ||||||||||
| Title: | Investigating the role of transcription factors of pancreas development in pancreatic cancer. | ||||||||||
| Author: | Naqvi, Ahmad Abu Turab|Hasan, Gulam Mustafa|Hassan, Md Imtaiyaz | ||||||||||
| PMID: | 29289465 | ||||||||||
| 38. | |||||||||||
| Journal: | Gastroenterology. 2018 Apr;154(5):1494-1508.e13. | ||||||||||
| Title: | Kruppel-like Factor 5, Increased in Pancreatic Ductal Adenocarcinoma, Promotes Proliferation, Acinar-to-Ductal Metaplasia, Pancreatic Intraepithelial Neoplasia, and Tumor Growth in Mice. | ||||||||||
| Author: | He, Ping|Yang, Jong Won|Yang, Vincent W|Bialkowska, Agnieszka B | ||||||||||
| PMID: | 29248441 | ||||||||||
| 39. | |||||||||||
| Journal: | J Biomol Struct Dyn. 2018 May;36(7):1834-1852. | ||||||||||
| Title: | Mechanistic insights into the activity of Ptf1-p48 (pancreas transcription factor 1a): probing the interactions levels of Ptf1-p48 with E2A-E47 (transcription factor E2-alpha) and ID3 (inhibitor of DNA binding 3). | ||||||||||
| Author: | Topno, Nishith Saurav|Kannan, Muthu|Krishna, Ramadas | ||||||||||
| PMID: | 28571517 | ||||||||||
| 40. | |||||||||||
| Journal: | Gut. 2018 Apr;67(4):707-718. | ||||||||||
| Title: | c-Myc downregulation is required for preacinar to acinar maturation and pancreatic homeostasis. | ||||||||||
| Author: | Sanchez-Arevalo Lobo, Victor J|Fernandez, Luis Cesar|Carrillo-de-Santa-Pau, Enrique|Richart, Laia|Cobo, Isidoro|Cendrowski, Jaroslaw|Moreno, Ulisses|Del Pozo, Natalia|Megias, Diego|Breant, Bernardette|Wright, Christopher V|Magnuson, Mark|Real, Francisco X | ||||||||||
| PMID: | 28159836 | ||||||||||