Literatures

Primary Site >> Liver Cancer

Gene >> PTEN

1.
Journal:	Oncogene. 1999 May 20;18(20):3181-5.
Title:	PTEN/MMAC1 mutations in hepatocellular carcinomas.
Author:	Yao, Y J\|Ping, X L\|Zhang, H\|Chen, F F\|Lee, P K\|Ahsan, H\|Chen, C J\|Lee, P H\|Peacocke, M\|Santella, R M\|Tsou, H C
PMID:	10340391

2.
Journal:	Cancer Invest. 2000;18(2):123-9.
Title:	Mutation analysis of the putative tumor suppressor gene PTEN/MMAC1 in hepatocellular carcinoma.
Author:	Yeh, K T\|Chang, J G\|Chen, Y J\|Chen, S T\|Yu, S Y\|Shih, M C\|Perng, L I\|Wang, J C\|Tsai, M\|Chang, C P
PMID:	10705874

3.
Journal:	Jpn J Cancer Res. 2000 Mar;91(3):287-92.
Title:	PTEN / MMAC1 mutation and frequent loss of heterozygosity identified in chromosome 10q in a subset of hepatocellular carcinomas.
Author:	Fujiwara, Y\|Hoon, D S\|Yamada, T\|Umeshita, K\|Gotoh, M\|Sakon, M\|Nishisho, I\|Monden, M
PMID:	10760687

4.
Journal:	Hepatology. 2000 Oct;32(4 Pt 1):796-802.
Title:	Hepatocyte growth factor promotes cell survival from fas-mediated cell death in hepatocellular carcinoma cells via Akt activation and Fas-death-inducing signaling complex suppression.
Author:	Suzuki, A\|Hayashida, M\|Kawano, H\|Sugimoto, K\|Nakano, T\|Shiraki, K
PMID:	11003625

5.
Journal:	Shi Yan Sheng Wu Xue Bao. 2000 Sep;33(3):223-7.
Title:	[Mutation analysis of the tumor suppressor gene PTEN/MMAC1/TEP1 in human hepatocellular carcinoma].
Author:	Zhang, L N\|Zha, X L\|Yu, Q\|He, J Y
PMID:	12549040

6.
Journal:	Int J Oncol. 2001 Jul;19(1):129-35.
Title:	Gene microarray analysis reveals a novel hypoxia signal transduction pathway in human hepatocellular carcinoma cells.
Author:	Scandurro, A B\|Weldon, C W\|Figueroa, Y G\|Alam, J\|Beckman, B S
PMID:	11408933

7.
Journal:	Int J Cancer. 2002 Jul 10;100(2):152-7.
Title:	Impact of PTEN expression on the outcome of hepatitis C virus-positive cirrhotic hepatocellular carcinoma patients: possible relationship with COX II and inducible nitric oxide synthase.
Author:	Rahman, Mohammad Atiqur\|Kyriazanos, Ioannis D\|Ono, Takashi\|Yamanoi, Akira\|Kohno, Hitoshi\|Tsuchiya, Mikako\|Nagasue, Naofumi
PMID:	12115563

8.
Journal:	BMC Cancer. 2002 Nov 15;2:29. Epub 2002 Nov 15.
Title:	Methylation profiling of twenty promoter-CpG islands of genes which may contribute to hepatocellular carcinogenesis.
Author:	Yu, Jian\|Ni, Min\|Xu, Jian\|Zhang, Hongyu\|Gao, Baomei\|Gu, Jianren\|Chen, Jianguo\|Zhang, Lisheng\|Wu, Mengchao\|Zhen, Sushen\|Zhu, Jingde
PMID:	12433278

9.
Journal:	Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai). 2003 Feb;35(2):161-6.
Title:	[The effects of PTEN gene on migration and FAK phosphorylation of SMMC-7721 human hepatocarcinoma cell line].
Author:	Zhang, Li-Neng\|Yu, Qiang\|Wang, Li-Ying\|Jin, Jia-Wei\|Zha, Xi-Liang
PMID:	12545224

10.
Journal:	Ai Zheng. 2003 Jan;22(1):42-5.
Title:	[Expression of phosphatase and tensin homology deleted on chromosome ten(PTEN) and p53 protein and their significance in human hepatocellular carcinomas].
Author:	Cheng, Li-Ming\|Wang, Si-Yuan\|Lin, Ju-Sheng
PMID:	12561434

11.
Journal:	Oncogene. 2003 Mar 27;22(12):1866-71.
Title:	Frequent epigenetic inactivation of the RASSF1A gene in hepatocellular carcinoma.
Author:	Schagdarsurengin, Undraga\|Wilkens, Ludwig\|Steinemann, Doris\|Flemming, Peer\|Kreipe, Hans H\|Pfeifer, Gerd P\|Schlegelberger, Brigitte\|Dammann, Reinhard
PMID:	12660822

12.
Journal:	Hepatology. 2003 Apr;37(4):852-61.
Title:	Homozygous deletion scanning in hepatobiliary tumor cell lines reveals alternative pathways for liver carcinogenesis.
Author:	Pineau, Pascal\|Marchio, Agnes\|Nagamori, Seishi\|Seki, Shuichi\|Tiollais, Pierre\|Dejean, Anne
PMID:	12668978

13.
Journal:	J Cancer Res Clin Oncol. 2003 Feb;129(2):100-6.
Title:	The alteration of PTEN tumor suppressor expression and its association with the histopathological features of human primary hepatocellular carcinoma.
Author:	Wan, X-W\|Jiang, M\|Cao, H-F\|He, Y-Q\|Liu, S-Q\|Qiu, X-H\|Wu, M-C\|Wang, H-Y
PMID:	12669234

14.
Journal:	Cancer. 2003 Apr 15;97(8):1929-40.
Title:	Expression and prognostic role of tumor suppressor gene PTEN/MMAC1/TEP1 in hepatocellular carcinoma.
Author:	Hu, Tsung-Hui\|Huang, Chao-Cheng\|Lin, Pey-Ru\|Chang, Hsueh-Wen\|Ger, Luo-Ping\|Lin, Yu-Wei\|Changchien, Chi-Sin\|Lee, Chuan-Mo\|Tai, Ming-Hong
PMID:	12673720

15.
Journal:	J Cell Mol Med. 2003 Jan-Mar;7(1):67-71.
Title:	Expression and significance of new tumor suppressor gene PTEN in primary liver cancer.
Author:	Dong-Dong, Lu\|Xi-Ran, Zhang\|Xiang-Rong, Cao
PMID:	12767263

16.
Journal:	FEBS Lett. 2003 Jun 19;545(2-3):203-8.
Title:	PTEN modulates insulin-like growth factor II (IGF-II)-mediated signaling; the protein phosphatase activity of PTEN downregulates IGF-II expression in hepatoma cells.
Author:	Kang-Park, Sukmi\|Lee, Yoon Ik\|Lee, Young Ik
PMID:	12804776

17.
Journal:	Liver Transpl. 2003 Jul;9(7):664-71.
Title:	Genotyping of hepatocellular carcinoma in liver transplant recipients adds predictive power for determining recurrence-free survival.
Author:	Marsh, J Wallis\|Finkelstein, Sydney D\|Demetris, Anthony J\|Swalsky, Patricia A\|Sasatomi, Eizaburo\|Bandos, Andriy\|Subotin, Michael\|Dvorchik, Igor
PMID:	12827550

18.
Journal:	Cancer Res. 2003 Jul 1;63(13):3453-8.
Title:	Hepatitis B Virus X protein modulates the expression of PTEN by inhibiting the function of p53, a transcriptional activator in liver cells.
Author:	Chung, Tae-Wook\|Lee, Young-Choon\|Ko, Jeong-Heon\|Kim, Cheorl-Ho
PMID:	12839924

19.
Journal:	Zhonghua Gan Zang Bing Za Zhi. 2003 Aug;11(8):490-2.
Title:	[PTEN expression and its significance in human primary hepatocellular carcinoma].
Author:	Wan, Xing-wang\|Wang, Hong-yang\|Jiang, Ming\|He, Ya-qin\|Liu, Shu-qin\|Cao, Hui-fang\|Qiu, Xiu-hua\|Tang, Liang\|Wu, Meng-chao
PMID:	12939185

20.
Journal:	Toxicol Pathol. 2004 Jan-Feb;32(1):64-72.
Title:	Subchronic exposure to arsenic through drinking water alters expression of cancer-related genes in rat liver.
Author:	Cui, Xing\|Li, Song\|Shraim, Amjad\|Kobayashi, Yayoi\|Hayakawa, Toru\|Kanno, Sanae\|Yamamoto, Megumi\|Hirano, Seishiro
PMID:	14713550

21.
Journal:	FASEB J. 2004 Jul;18(10):1123-5.
Title:	Hepatitis B viral HBx induces matrix metalloproteinase-9 gene expression through activation of ERK and PI-3K/AKT pathways: involvement of invasive potential.
Author:	Chung, Tae-Wook\|Lee, Young-Choon\|Kim, Cheorl-Ho
PMID:	15132991

22.
Journal:	Ai Zheng. 2004 Jun;23(6):662-6.
Title:	[Expression of PTEN, Cx43, and VEGF in hepatocellular carcinoma].
Author:	Zhang, Tian-Yi\|An, Jun-Ling\|Gu, Jun-Yi\|He, Song
PMID:	15191666

23.
Journal:	J Clin Invest. 2004 Jun;113(12):1774-83.
Title:	Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas.
Author:	Horie, Yasuo\|Suzuki, Akira\|Kataoka, Ei\|Sasaki, Takehiko\|Hamada, Koichi\|Sasaki, Junko\|Mizuno, Katsunori\|Hasegawa, Go\|Kishimoto, Hiroyuki\|Iizuka, Masahiro\|Naito, Makoto\|Enomoto, Katsuhiko\|Watanabe, Sumio\|Mak, Tak Wah\|Nakano, Toru
PMID:	15199412

24.
Journal:	Int J Oncol. 2004 Nov;25(5):1357-64.
Title:	Genetic alterations in doxorubicin-resistant hepatocellular carcinoma cells: a combined study of spectral karyotyping, positional expression profiling and candidate genes.
Author:	Hu, Ying\|Pang, Elizabeth\|Lai, Paul B-S\|Squire, Jeremy A\|MacGregor, Pascale F\|Beheshti, Ben\|Albert, Monique\|Leung, Thomas W-T\|Wong, Nathalie
PMID:	15492826

25.
Journal:	Mol Cell Biochem. 2004 Jul;262(1-2):25-33.
Title:	Study of the PTEN gene expression and FAK phosphorylation in human hepatocarcinoma tissues and cell lines.
Author:	Zhang, Lineng\|Yu, Qiang\|He, Jianyu\|Zha, Xiliang
PMID:	15532706

26.
Journal:	J Huazhong Univ Sci Technolog Med Sci. 2005;25(1):45-7.
Title:	Correlation between loss of PTEN expression and PKB/AKT phosphorylation in hepatocellular carcinoma.
Author:	Yang, Zhifang\|Yi, Jilin\|Li, Xingrui\|Long, Wei
PMID:	15934306

27.
Journal:	World J Gastroenterol. 2005 Aug 7;11(29):4472-7.
Title:	Down-regulation of PTEN expression due to loss of promoter activity in human hepatocellular carcinoma cell lines.
Author:	Ma, Dong-Zhu\|Xu, Zhen\|Liang, Yu-Long\|Su, Jian-Ming\|Li, Zeng-Xia\|Zhang, Wen\|Wang, Li-Ying\|Zha, Xi-Liang
PMID:	16052674

28.
Journal:	Nihon Rinsho. 2005 Aug;63(8):1475-83.
Title:	[Tumor suppressor gene PTEN and non-alcoholic steatohepatitis (NASH)].
Author:	Sato, Wataru\|Horie, Yasuo\|Watanabe, Sumio\|Suzuki, Akira
PMID:	16101243

29.
Journal:	Hepatol Res. 2005 Oct;33(2):161-6.
Title:	Hepatocyte-specific Pten-deficient mice as a novel model for nonalcoholic steatohepatitis and hepatocellular carcinoma.
Author:	Watanabe, Sumio\|Horie, Yasuo\|Suzuki, Akira
PMID:	16214396

30.
Journal:	Cancer Res. 2006 May 15;66(10):5346-53.
Title:	PTEN/Akt signaling through epidermal growth factor receptor is prerequisite for angiogenesis by hepatocellular carcinoma cells that is susceptible to inhibition by gefitinib.
Author:	Ueda, Shu-Ichi\|Basaki, Yuji\|Yoshie, Masumi\|Ogawa, Katsuhiro\|Sakisaka, Shotaro\|Kuwano, Michihiko\|Ono, Mayumi
PMID:	16707461

31.
Journal:	Nihon Rinsho. 2006 Jun;64(6):1033-42.
Title:	[Hepatocyte-specific Pten deficient mice].
Author:	Horie, Yasuo\|Ohshima, Shigetoshi\|Sato, Wataru\|Suzuki, Akira\|Watanabe, Sumio
PMID:	16768106

32.
Journal:	Virus Res. 2006 Dec;122(1-2):53-60.
Title:	PTEN modulates hepatitis B virus-X protein induced survival signaling in Chang liver cells.
Author:	Kang-Park, Sukmi\|Im, Jee H\|Lee, Je H\|Lee, Young I
PMID:	16872708

33.
Journal:	Mol Carcinog. 2006 Dec;45(12):901-13.
Title:	Neoplastic hepatocyte growth associated with cyclin D1 redistribution from the cytoplasm to the nucleus in mouse hepatocarcinogenesis.
Author:	Yamamoto, Masahiro\|Tamakawa, Susumu\|Yoshie, Masumi\|Yaginuma, Yuji\|Ogawa, Katsuhiro
PMID:	17013836

34.
Journal:	Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2006 Oct;31(5):682-6, 695.
Title:	[Anti-tumor effect and mechanism of Paeonol on the hepatocellular carcinoma cell line Bel-7404].
Author:	Zhang, Chun-hu\|Hu, Sui-yu\|Li, Yun-hui\|Cao, Mei-qun
PMID:	17062930

35.
Journal:	Zhonghua Bing Li Xue Za Zhi. 2006 Aug;35(8):467-72.
Title:	[Mutations of tumor suppressor gene PTEN mutations in hepatocellular carcinoma and its implications in tumor proliferation and apoptosis].
Author:	Guo, Shuang-ping\|Wang, Li\|Wang, Wen-liang\|Li, Qin-long\|Wang, Wen-yong\|Zhang, Jing
PMID:	17069699

36.
Journal:	Liver Int. 2007 Mar;27(2):155-62.
Title:	Survival and apoptosis: a dysregulated balance in liver cancer.
Author:	Fabregat, Isabel\|Roncero, Cesar\|Fernandez, Margarita
PMID:	17311609

37.
Journal:	Transplantation. 2007 Feb 27;83(4):425-32.
Title:	Mammalian target of rapamycin pathway activity in hepatocellular carcinomas of patients undergoing liver transplantation.
Author:	Sieghart, Wolfgang\|Fuereder, Thorsten\|Schmid, Katharina\|Cejka, Daniel\|Werzowa, Johannes\|Wrba, Fritz\|Wang, Xiaowei\|Gruber, Diego\|Rasoul-Rockenschaub, Susanne\|Peck-Radosavljevic, Markus\|Wacheck, Volker
PMID:	17318075

38.
Journal:	Hepatol Res. 2007 May;37(5):389-96.
Title:	Epigenetic and genetic alterations of PTEN in hepatocellular carcinoma.
Author:	Wang, Li\|Wang, Wen-Liang\|Zhang, Yong\|Guo, Shuang-Ping\|Zhang, Jing\|Li, Qin-Long
PMID:	17441812

39.
Journal:	Acta Pharmacol Sin. 2007 Jun;28(6):879-87.
Title:	Upregulation of PTEN involved in rosiglitazone-induced apoptosis in human hepatocellular carcinoma cells.
Author:	Cao, Liang-Qi\|Chen, Xi-Lin\|Wang, Qian\|Huang, Xiao-Hui\|Zhen, Mao-Chuan\|Zhang, Long-Juan\|Li, Wen\|Bi, Jiong
PMID:	17506947

40.
Journal:	J Gastroenterol Hepatol. 2007 Jun;22 Suppl 1:S96-S100.
Title:	Non-alcoholic steatohepatitis and hepatocellular carcinoma: lessons from hepatocyte-specific phosphatase and tensin homolog (PTEN)-deficient mice.
Author:	Watanabe, Sumio\|Horie, Yasuo\|Kataoka, Ei\|Sato, Wataru\|Dohmen, Takahiro\|Ohshima, Shigetoshi\|Goto, Takashi\|Suzuki, Akira
PMID:	17567478

41.
Journal:	Zhongguo Zhong Yao Za Zhi. 2007 Jun;32(11):1057-60.
Title:	[Expression of PTEN in athymic mice with HCC treated by complex prescription of Chinese crude drug].
Author:	Sun, Bao-guo\|Chen, Ze-xiong\|Zhang, Shi-jun\|Liu, Yong-dong\|Huang, Hong-zhong\|Yin, Li-rong
PMID:	17672343

42.
Journal:	Gastroenterology. 2007 Aug;133(2):647-58.
Title:	MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer.
Author:	Meng, Fanyin\|Henson, Roger\|Wehbe-Janek, Hania\|Ghoshal, Kalpana\|Jacob, Samson T\|Patel, Tushar
PMID:	17681183

43.
Journal:	Zhonghua Gan Zang Bing Za Zhi. 2007 Aug;15(8):567-71.
Title:	[Expressions of phosphorylated-Smad2 and PTEN in hepatocellular carcinomas and adjacent liver tissues].
Author:	Wu, Shu-kun\|Wang, Bao-ju\|Yang, Yan\|Tian, Yong-jun\|Bao, Jun-jie\|Feng, Xin-hua\|Yang, Dong-liang
PMID:	17711623

44.
Journal:	World J Gastroenterol. 2007 Sep 14;13(34):4554-9.
Title:	Expression of PTEN, PPM1A and P-Smad2 in hepatocellular carcinomas and adjacent liver tissues.
Author:	Wu, Shu-Kun\|Wang, Bao-Ju\|Yang, Yan\|Feng, Xin-Hua\|Zhao, Xi-Ping\|Yang, Dong-Liang
PMID:	17729405

45.
Journal:	Oncol Rep. 2007 Oct;18(4):1007-13.
Title:	Loss of heterozygosity on chromosome 10q23 and mutation of the phosphatase and tensin homolog deleted from chromosome 10 tumor suppressor gene in Korean hepatocellular carcinoma patients.
Author:	Bae, Jei-Jun\|Rho, Jin-Woo\|Lee, Tae-Jin\|Yun, Sung-Su\|Kim, Hong-Jin\|Choi, Joon-Hyuk\|Jeong, Daewon\|Jang, Byeong-Churl\|Lee, Tae-Yoon
PMID:	17786367

46.
Journal:	World J Gastroenterol. 2007 Oct 28;13(40):5299-305.
Title:	Effects and mechanisms of silibinin on human hepatoma cell lines.
Author:	Lah, John-J\|Cui, Wei\|Hu, Ke-Qin
PMID:	17879397

47.
Journal:	Oncol Rep. 2007 Dec;18(6):1417-26.
Title:	Down-regulation of tumor suppressor gene PTEN, overexpression of p53, plus high proliferating cell nuclear antigen index predict poor patient outcome of hepatocellular carcinoma after resection.
Author:	Hu, Tsung-Hui\|Wang, Chih-Chi\|Huang, Chao-Cheng\|Chen, Chao-Long\|Hung, Chao-Hung\|Chen, Chien-Hung\|Wang, Jing-Houng\|Lu, Sheng-Nan\|Lee, Chuan-Mo\|Changchien, Chi-Sin\|Tai, Ming-Hong
PMID:	17982625

48.
Journal:	Zhong Yao Cai. 2007 Nov;30(11):1417-21.
Title:	[Study of antitumous effect of the complex prescription of Chinese crude drug in athymic mice with HCC].
Author:	Sun, Bao-guo\|Chen, Ze-xiong\|Zhang, Shi-jun\|Liu, Yong-dong\|Huang, Hong-zhong\|Yin, Li-rong
PMID:	18323213

49.
Journal:	Dig Dis Sci. 2008 Mar;53(3):844-9.
Title:	Immunohistochemical expression of components of the Akt-mTORC1 pathway is associated with hepatocellular carcinoma in patients with chronic liver disease.
Author:	Cotler, Scott J\|Hay, Nissim\|Xie, Hui\|Chen, Mei Ling\|Xu, Pei Zhang\|Layden, Thomas J\|Guzman, Grace
PMID:	17763954

50.
Journal:	Gastroenterology. 2008 Jan;134(1):268-80.
Title:	PTEN down-regulation by unsaturated fatty acids triggers hepatic steatosis via an NF-kappaBp65/mTOR-dependent mechanism.
Author:	Vinciguerra, Manlio\|Veyrat-Durebex, Christelle\|Moukil, Moulay Ahmed\|Rubbia-Brandt, Laura\|Rohner-Jeanrenaud, Francoise\|Foti, Michelangelo
PMID:	18166358

51.
Journal:	World J Gastroenterol. 2008 Jan 7;14(1):108-13.
Title:	Expression of phosphatase and tensin homolog deleted on chromosome ten in liver of athymic mice with hepatocellular carcinoma and the effect of Fuzheng Jiedu Decoction.
Author:	Yin, Li-Rong\|Chen, Ze-Xiong\|Zhang, Shi-Jun\|Sun, Bao-Guo\|Liu, Yong-Dong\|Huang, Hong-Zhong
PMID:	18176971

52.
Journal:	Zhonghua Gan Zang Bing Za Zhi. 2008 Jan;16(1):17-20.
Title:	[Expression of survivin, p27 and PTEN in hepatocellular carcinoma and their clinical significances].
Author:	Huang, Ai-min\|Ding, Yi\|Liu, Jing-feng\|Gao, Ling-yun\|Zang, Sheng-bing\|Chen, Shui-ping
PMID:	18226337

53.
Journal:	FEBS Lett. 2008 May 28;582(12):1667-71.
Title:	Alpha-lipoic acid induces apoptosis in hepatoma cells via the PTEN/Akt pathway.
Author:	Shi, Dong-Yun\|Liu, Hong-Lei\|Stern, Jeremy S\|Yu, Pei-Zhong\|Liu, Shan-Lin
PMID:	18435927

54.
Journal:	Anticancer Drugs. 2008 Apr;19(4):401-9.
Title:	Antiproliferative and apoptotic effects of paeonol on human hepatocellular carcinoma cells.
Author:	Chunhu, Zhang\|Suiyu, Hu\|Meiqun, Cao\|Guilin, Xiao\|Yunhui, Li
PMID:	18454050

55.
Journal:	Exp Mol Pathol. 2008 Dec;85(3):223-6.
Title:	Osteogenic tumours in Lkb1-deficient mice.
Author:	Robinson, James\|Nye, Emma\|Stamp, Gordon\|Silver, Andrew
PMID:	18761009

56.
Journal:	Ann Hepatol. 2008 Jul-Sep;7(3):192-9.
Title:	PTEN at the crossroad of metabolic diseases and cancer in the liver.
Author:	Vinciguerra, Manlio\|Foti, Michelangelo
PMID:	18772845

57.
Journal:	Gastroenterology. 2008 Dec;135(6):1972-83, 1983.e1-11.
Title:	Pivotal role of mTOR signaling in hepatocellular carcinoma.
Author:	Villanueva, Augusto\|Chiang, Derek Y\|Newell, Pippa\|Peix, Judit\|Thung, Swan\|Alsinet, Clara\|Tovar, Victoria\|Roayaie, Sasan\|Minguez, Beatriz\|Sole, Manel\|Battiston, Carlo\|Van Laarhoven, Stijn\|Fiel, Maria I\|Di Feo, Analisa\|Hoshida, Yujin\|Yea, Steven\|Toffanin, S
PMID:	18929564

58.
Journal:	Liver Int. 2009 Jan;29(1):126-32.
Title:	Differences in molecular alterations of hepatocellular carcinoma between patients with a sustained virological response and those with hepatitis C virus infection.
Author:	Hayashi, Takehiro\|Tamori, Akihiro\|Nishikawa, Manabu\|Morikawa, Hiroyasu\|Enomoto, Masaru\|Sakaguchi, Hiroki\|Habu, Daiki\|Kawada, Norifumi\|Kubo, Shoji\|Nishiguchi, Shuhei\|Shiomi, Susumu
PMID:	18492017

59.
Journal:	Stem Cells. 2009 Feb;27(2):290-9.
Title:	Expansion of CD133-expressing liver cancer stem cells in liver-specific phosphatase and tensin homolog deleted on chromosome 10-deleted mice.
Author:	Rountree, C Bart\|Ding, Wei\|He, Lina\|Stiles, Bangyan
PMID:	19008348

60.
Journal:	World J Surg. 2009 Apr;33(4):647-52.
Title:	Sequencing the full-length of the phosphatase and tensin homolog (PTEN) gene in hepatocellular carcinoma (HCC) using the 454 GS20 and Illumina GA DNA sequencing platforms.
Author:	Rodriguez, Joel A\|Guiteau, Jacfranz J\|Nazareth, Lynne\|Reid, Jeff G\|Goss, John A\|Gibbs, Richard A\|Gingras, Marie-Claude
PMID:	19082655

61.
Journal:	Liver Int. 2009 Jul;29(6):846-56.
Title:	Oxidative stress may enhance the malignant potential of human hepatocellular carcinoma by telomerase activation.
Author:	Nishikawa, Taichiro\|Nakajima, Tomoki\|Katagishi, Tatsuo\|Okada, Yoshihisa\|Jo, Masayasu\|Kagawa, Keizo\|Okanoue, Takeshi\|Itoh, Yoshito\|Yoshikawa, Toshikazu
PMID:	19141026

62.
Journal:	J Hepatol. 2009 Mar;50(3):562-71.
Title:	Eicosapentaenoic acid ameliorates steatohepatitis and hepatocellular carcinoma in hepatocyte-specific Pten-deficient mice.
Author:	Ishii, Hajime\|Horie, Yasuo\|Ohshima, Shigetoshi\|Anezaki, Yumiko\|Kinoshita, Nobukatsu\|Dohmen, Takahiro\|Kataoka, Ei\|Sato, Wataru\|Goto, Takashi\|Sasaki, Junko\|Sasaki, Takehiko\|Watanabe, Sumio\|Suzuki, Akira\|Ohnishi, Hirohide
PMID:	19162361

63.
Journal:	Hepatol Res. 2009 Feb;39(2):177-86.
Title:	Involvement of PI3K/PTEN/AKT/mTOR pathway in invasion and metastasis in hepatocellular carcinoma: Association with MMP-9.
Author:	Chen, Jing-Song\|Wang, Qian\|Fu, Xin-Hui\|Huang, Xiao-Hui\|Chen, Xi-Lin\|Cao, Liang-Qi\|Chen, Lian-Zhou\|Tan, Hao-Xiang\|Li, Wen\|Bi, Jiong\|Zhang, Long-Juan
PMID:	19208038

64.
Journal:	J Hepatol. 2009 Jun;50(6):1132-41.
Title:	Unsaturated fatty acids promote hepatoma proliferation and progression through downregulation of the tumor suppressor PTEN.
Author:	Vinciguerra, Manlio\|Carrozzino, Fabio\|Peyrou, Marion\|Carlone, Sebastiano\|Montesano, Roberto\|Benelli, Roberto\|Foti, Michelangelo
PMID:	19398230

65.
Journal:	World J Gastroenterol. 2009 Apr 28;15(16):1943-50.
Title:	Effects and mechanisms of silibinin on human hepatocellular carcinoma xenografts in nude mice.
Author:	Cui, Wei\|Gu, Fan\|Hu, Ke-Qin
PMID:	19399925

66.
Journal:	Acta Pharmacol Sin. 2009 Sep;30(9):1316-22.
Title:	Rosiglitazone sensitizes hepatocellular carcinoma cell lines to 5-fluorouracil antitumor activity through activation of the PPARgamma signaling pathway.
Author:	Cao, Liang-qi\|Wang, Xiao-li\|Wang, Qian\|Xue, Ping\|Jiao, Xing-yuan\|Peng, He-ping\|Lu, Hai-wu\|Zheng, Qiang\|Chen, Xi-lin\|Huang, Xiao-hui\|Fu, Xin-hui\|Chen, Jing-song
PMID:	19684609

67.
Journal:	Zhongguo Zhong Yao Za Zhi. 2009 May;34(9):1144-8.
Title:	[Effect of Jianpi Jiedu decoction to PTEN/ERK1 of athymic mice with hepatocellular carcinoma].
Author:	Sun, Baoguo\|Zhou, Houming\|Deng, Yicai\|Huang, Hongzhong\|Chen, Zexiong\|Zhang, Shijun
PMID:	19685755

68.
Journal:	Hepatology. 2009 Oct;50(4):1152-61.
Title:	Role of microRNA-155 at early stages of hepatocarcinogenesis induced by choline-deficient and amino acid-defined diet in C57BL/6 mice.
Author:	Wang, Bo\|Majumder, Sarmila\|Nuovo, Gerard\|Kutay, Huban\|Volinia, Stefano\|Patel, Tushar\|Schmittgen, Thomas D\|Croce, Carlo\|Ghoshal, Kalpana\|Jacob, Samson T
PMID:	19711427

69.
Journal:	Clin Cancer Res. 2009 Sep 15;15(18):5895-901.
Title:	A multi-institutional phase II study of the efficacy and tolerability of lapatinib in patients with advanced hepatocellular carcinomas.
Author:	Bekaii-Saab, Tanios\|Markowitz, Joseph\|Prescott, Nichole\|Sadee, Wolfgang\|Heerema, Nyla\|Wei, Lai\|Dai, Zunyan\|Papp, Audrey\|Campbell, Angela\|Culler, Kristy\|Balint, Catherine\|O'Neil, Bert\|Lee, Ruey-Min\|Zalupski, Mark\|Dancey, Janet\|Chen, Helen\|Grever, Michael\|E
PMID:	19737952

70.
Journal:	Cancer Cell. 2009 Dec 8;16(6):498-509.
Title:	miR-221&222 regulate TRAIL resistance and enhance tumorigenicity through PTEN and TIMP3 downregulation.
Author:	Garofalo, Michela\|Di Leva, Gianpiero\|Romano, Giulia\|Nuovo, Gerard\|Suh, Sung-Suk\|Ngankeu, Apollinaire\|Taccioli, Cristian\|Pichiorri, Flavia\|Alder, Hansjuerg\|Secchiero, Paola\|Gasparini, Pierluigi\|Gonelli, Arianna\|Costinean, Stefan\|Acunzo, Mario\|Condorelli, G
PMID:	19962668

71.
Journal:	Viruses. 2009 Dec;1(3):852-72.
Title:	Molecular mechanisms underlying hepatocellular carcinoma.
Author:	Merle, Philippe\|Trepo, Christian
PMID:	21994573

72.
Journal:	Med Oncol. 2010 Jun;27(2):255-61.
Title:	The mTOR pathway is associated with the poor prognosis of human hepatocellular carcinoma.
Author:	Zhou, Ledu\|Huang, Yun\|Li, Jingdong\|Wang, Zhiming
PMID:	19301157

73.
Journal:	Chem Biol Interact. 2010 Jan 27;183(2):284-92.
Title:	Morin fosters apoptosis in experimental hepatocellular carcinogenesis model.
Author:	Sivaramakrishnan, Venkatabalasubramanian\|Devaraj, Sivasitambaram Niranjali
PMID:	19931519

74.
Journal:	Angiogenesis. 2010 Mar;13(1):59-69.
Title:	VHL and PTEN loss coordinate to promote mouse liver vascular lesions.
Author:	Chen, Shufen\|Sanford, Christie A\|Sun, Junjiang\|Choi, Vivian\|Van Dyke, Terry\|Samulski, R Jude\|Rathmell, W Kimryn
PMID:	20221685

75.
Journal:	Oncol Rep. 2010 Jun;23(6):1593-600.
Title:	PTEN inhibits the migration and invasion of HepG2 cells by coordinately decreasing MMP expression via the PI3K/Akt pathway.
Author:	Tian, Tao\|Nan, Ke-Jun\|Guo, Hui\|Wang, Wen-Juan\|Ruan, Zhi-Ping\|Wang, Shu-Hong\|Liang, Xuan\|Lu, Chuang-Xin
PMID:	20428814

76.
Journal:	Carcinogenesis. 2010 Jul;31(7):1211-9.
Title:	PTEN regulates angiogenesis and VEGF expression through phosphatase-dependent and -independent mechanisms in HepG2 cells.
Author:	Tian, Tao\|Nan, Ke-Jun\|Wang, Shu-Hong\|Liang, Xuan\|Lu, Chuang-Xin\|Guo, Hui\|Wang, Wen-Juan\|Ruan, Zhi-Ping
PMID:	20430845

77.
Journal:	J Hepatol. 2010 Jul;53(1):98-107.
Title:	MicroRNA-21 acts as an oncomir through multiple targets in human hepatocellular carcinoma.
Author:	Liu, Changzheng\|Yu, Jia\|Yu, Shuangni\|Lavker, Robert M\|Cai, Lei\|Liu, Wei\|Yang, Kegong\|He, Xiaodong\|Chen, Songsen
PMID:	20447717

78.
Journal:	Dig Dis. 2010;28(1):236-46.
Title:	PTEN in non-alcoholic fatty liver disease/non-alcoholic steatohepatitis and cancer.
Author:	Peyrou, Marion\|Bourgoin, Lucie\|Foti, Michelangelo
PMID:	20460918

79.
Journal:	J Biomed Biotechnol. 2010;2010:737535.
Title:	Depletion of DNMT3A suppressed cell proliferation and restored PTEN in hepatocellular carcinoma cell.
Author:	Zhao, Zhujiang\|Wu, Qingxiang\|Cheng, Jian\|Qiu, Xuemei\|Zhang, Jianqiong\|Fan, Hong
PMID:	20467490

80.
Journal:	Cancer Res. 2010 Jul 1;70(13):5305-15.
Title:	The phosphoinositide 3-kinase regulatory subunit p85alpha can exert tumor suppressor properties through negative regulation of growth factor signaling.
Author:	Taniguchi, Cullen M\|Winnay, Jonathon\|Kondo, Tatsuya\|Bronson, Roderick T\|Guimaraes, Alexander R\|Aleman, Jose O\|Luo, Ji\|Stephanopoulos, Gregory\|Weissleder, Ralph\|Cantley, Lewis C\|Kahn, C Ronald
PMID:	20530665

81.
Journal:	Hepatology. 2010 Sep;52(3):945-53.
Title:	Epithelial-to-mesenchymal transition of murine liver tumor cells promotes invasion.
Author:	Ding, Wei\|You, Hanning\|Dang, Hien\|LeBlanc, Francis\|Galicia, Vivian\|Lu, Shelly C\|Stiles, Bangyan\|Rountree, C Bart
PMID:	20564331

82.
Journal:	Gastroenterology. 2010 Dec;139(6):2170-82.
Title:	Expansion of hepatic tumor progenitor cells in Pten-null mice requires liver injury and is reversed by loss of AKT2.
Author:	Galicia, Vivian A\|He, Lina\|Dang, Hien\|Kanel, Gary\|Vendryes, Christopher\|French, Barbara A\|Zeng, Ni\|Bayan, Jennifer-Ann\|Ding, Wei\|Wang, Kasper S\|French, Samuel\|Birnbaum, Morris J\|Rountree, C Bart\|Stiles, Bangyan L
PMID:	20837017

83.
Journal:	World J Gastroenterol. 2010 Oct 7;16(37):4627-33.
Title:	PTEN in liver diseases and cancer.
Author:	Peyrou, Marion\|Bourgoin, Lucie\|Foti, Michelangelo
PMID:	20872961

84.
Journal:	Hepatology. 2010 Dec;52(6):2034-43.
Title:	Genetic variations at loci involved in the immune response are risk factors for hepatocellular carcinoma.
Author:	Clifford, Robert J\|Zhang, Jinghui\|Meerzaman, Daoud M\|Lyu, Myung-Soo\|Hu, Ying\|Cultraro, Constance M\|Finney, Richard P\|Kelley, Jenny M\|Efroni, Sol\|Greenblum, Sharon I\|Nguyen, Cu V\|Rowe, William L\|Sharma, Sweta\|Wu, Gang\|Yan, Chunhua\|Zhang, Hongen\|Chung, Youn
PMID:	21105107

85.
Journal:	Hepatogastroenterology. 2010 Sep-Oct;57(102-103):1247-56.
Title:	Increased DJ-1 and its prognostic significance in hepatocellular carcinoma.
Author:	Liu, Shunfang\|Yang, Zhifang\|Wei, Honglan\|Shen, Wenzhuang\|Liu, Jinwen\|Yin, Qian\|Li, Xingrui\|Yi, Jilin
PMID:	21410067

86.
Journal:	Int J Cancer. 2011 Feb 1;128(3):524-32.
Title:	Alpha-fetoprotein: a new member of intracellular signal molecules in regulation of the PI3K/AKT signaling in human hepatoma cell lines.
Author:	Li, Mengsen\|Li, Hui\|Li, Chaoying\|Wang, Shanshan\|Jiang, Wei\|Liu, Zhongmin\|Zhou, Sheng\|Liu, Xinhua\|McNutt, Michael A\|Li, Gang
PMID:	20473866

87.
Journal:	Amino Acids. 2011 Mar;40(3):1003-13.
Title:	ESM-1 silencing decreased cell survival, migration, and invasion and modulated cell cycle progression in hepatocellular carcinoma.
Author:	Kang, Yun Hee\|Ji, Na Young\|Lee, Chung Il\|Lee, Hee Gu\|Kim, Jae Wha\|Yeom, Young Il\|Kim, Dae Ghon\|Yoon, Seung Kew\|Kim, Jong Wan\|Park, Pil Je\|Song, Eun Young
PMID:	20821239

88.
Journal:	Hepatology. 2011 Jan;53(1):160-70.
Title:	Lupeol targets liver tumor-initiating cells through phosphatase and tensin homolog modulation.
Author:	Lee, Terence Kin Wah\|Castilho, Antonia\|Cheung, Vincent Chi Ho\|Tang, Kwan Ho\|Ma, Stephanie\|Ng, Irene Oi Lin
PMID:	20979057

89.
Journal:	DNA Cell Biol. 2011 Apr;30(4):229-34.
Title:	Association of PTEN polymorphisms with susceptibility to hepatocellular carcinoma in a Han Chinese population.
Author:	Ding, Jun\|Gao, Yuzhen\|Liu, Rengyu\|Xu, Fei\|Liu, Haiyan
PMID:	21138334

90.
Journal:	J Hepatol. 2011 May;54(5):994-1001.
Title:	Overexpression of the IGF2-mRNA binding protein p62 in transgenic mice induces a steatotic phenotype.
Author:	Tybl, Elisabeth\|Shi, Fu-Dong\|Kessler, Sonja M\|Tierling, Sascha\|Walter, Jorn\|Bohle, Rainer M\|Wieland, Stefan\|Zhang, Jianying\|Tan, Eng M\|Kiemer, Alexandra K
PMID:	21145819

91.
Journal:	J Hepatol. 2011 May;54(5):939-47.
Title:	Aberrant CpG island hypermethylation in dysplastic nodules and early HCC of hepatitis B virus-related human multistep hepatocarcinogenesis.
Author:	Um, Tae-Hee\|Kim, Haeryoung\|Oh, Bong-Kyeong\|Kim, Myoung Soo\|Kim, Kyung Sik\|Jung, Guhung\|Park, Young Nyun
PMID:	21145824

92.
Journal:	Vet Pathol. 2011 Jul;48(4):875-84.
Title:	Gene expression and mutation assessment provide clues of genetic and epigenetic mechanisms in liver tumors of oxazepam-exposed mice.
Author:	Lahousse, S A\|Hoenerhoff, M\|Collins, J\|Ton, T-V T\|Masinde, T\|Olson, D\|Rebolloso, Y\|Koujitani, T\|Tomer, K B\|Hong, H-H L\|Bucher, J\|Sills, R C
PMID:	21147764

93.
Journal:	Hepatol Res. 2011 Feb;41(2):189-93.
Title:	Cowden syndrome complicated with hepatocellular carcinoma possibly originating from non-alcoholic steatohepatitis (NASH).
Author:	Sugihara, Takaaki\|Mandai, Mari\|Koda, Masahiko\|Matono, Tomomitsu\|Nagahara, Takakazu\|Ueki, Masaru\|Murawaki, Yoshikazu
PMID:	21269388

94.
Journal:	Mol Pharmacol. 2011 Jun;79(6):941-52.
Title:	Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) inhibition by 4-hydroxynonenal leads to increased Akt activation in hepatocytes.
Author:	Shearn, Colin T\|Smathers, Rebecca L\|Stewart, Benjamin J\|Fritz, Kristofer S\|Galligan, James J\|Hail, Numsen Jr\|Petersen, Dennis R
PMID:	21415306

95.
Journal:	Hepatology. 2011 Jul;54(1):38-49.
Title:	Down-regulation of phosphatase and tensin homolog by hepatitis C virus core 3a in hepatocytes triggers the formation of large lipid droplets.
Author:	Clement, Sophie\|Peyrou, Marion\|Sanchez-Pareja, Andrea\|Bourgoin, Lucie\|Ramadori, Pierluigi\|Suter, David\|Vinciguerra, Manlio\|Guilloux, Kevin\|Pascarella, Stephanie\|Rubbia-Brandt, Laura\|Negro, Francesco\|Foti, Michelangelo
PMID:	21465511

96.
Journal:	Hepatology. 2011 May;53(5):1558-69.
Title:	Loss of phosphatase and tensin homolog enhances cell invasion and migration through AKT/Sp-1 transcription factor/matrix metalloproteinase 2 activation in hepatocellular carcinoma and has clinicopathologic significance.
Author:	Sze, Karen Man-Fong\|Wong, Kris Lai-Ting\|Chu, Glanice Kin-Yan\|Lee, Joyce Man-Fong\|Yau, Tai-On\|Ng, Irene Oi-Lin
PMID:	21520171

97.
Journal:	PLoS One. 2011 May 5;6(5):e19518.
Title:	Upregulated microRNA-29a by hepatitis B virus X protein enhances hepatoma cell migration by targeting PTEN in cell culture model.
Author:	Kong, Guangyao\|Zhang, Junping\|Zhang, Shuai\|Shan, Changliang\|Ye, Lihong\|Zhang, Xiaodong
PMID:	21573166

98.
Journal:	Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2011 May;36(5):381-5.
Title:	MAGI1 inhibits cancer cell migration and invasion of hepatocellular carcinoma via regulating PTEN.
Author:	Zhang, Gewen\|Wang, Zhiming
PMID:	21685691

99.
Journal:	J Hepatol. 2011 Dec;55(6):1400-8.
Title:	Altered composition of fatty acids exacerbates hepatotumorigenesis during activation of the phosphatidylinositol 3-kinase pathway.
Author:	Kudo, Yotaro\|Tanaka, Yasuo\|Tateishi, Keisuke\|Yamamoto, Keisuke\|Yamamoto, Shinzo\|Mohri, Dai\|Isomura, Yoshihiro\|Seto, Motoko\|Nakagawa, Hayato\|Asaoka, Yoshinari\|Tada, Motohisa\|Ohta, Miki\|Ijichi, Hideaki\|Hirata, Yoshihiro\|Otsuka, Motoyuki\|Ikenoue, Tsuneo\|Maed
PMID:	21703185

100.
Journal:	Oncol Rep. 2011 Nov;26(5):1273-9.
Title:	Growth inhibition by NVP-BEZ235, a dual PI3K/mTOR inhibitor, in hepatocellular carcinoma cell lines.
Author:	Masuda, Mitsuhiro\|Shimomura, Manami\|Kobayashi, Ken\|Kojima, Shuji\|Nakatsura, Tetsuya
PMID:	21725613

101.
Journal:	PLoS Genet. 2011 Jun;7(6):e1002147.
Title:	Extracellular matrix dynamics in hepatocarcinogenesis: a comparative proteomics study of PDGFC transgenic and Pten null mouse models.
Author:	Lai, Keane K Y\|Shang, Sufen\|Lohia, Neha\|Booth, Garrett C\|Masse, Derek J\|Fausto, Nelson\|Campbell, Jean S\|Beretta, Laura
PMID:	21731504

102.
Journal:	Mutat Res. 2011 Oct 1;715(1-2):42-51.
Title:	Inactivation of PTEN is responsible for the survival of Hep G2 cells in response to etoposide-induced damage.
Author:	Mukherjee, Ananda\|Samanta, Saheli\|Karmakar, Parimal
PMID:	21784088

103.
Journal:	Cancer Cell Int. 2011 Oct 28;11:36.
Title:	Effect of Benzothiazole based conjugates in causing apoptosis by Regulating p53, PTEN and MAP Kinase proteins affecting miR-195a and miR-101-1.
Author:	Pushpavalli, Sncvl\|Ramaiah, M Janaki\|Srinivas, Ch\|Mukhopadhya, Debasmita\|Aditya, J L\|Kumbhare, Ravindra M\|Bhadra, Utpal\|Bhadra, Manika Pal
PMID:	22035408

104.
Journal:	Int J Cancer. 2012 Mar 15;130(6):1294-301.
Title:	Excessive activity of apolipoprotein B mRNA editing enzyme catalytic polypeptide 2 (APOBEC2) contributes to liver and lung tumorigenesis.
Author:	Okuyama, Shunsuke\|Marusawa, Hiroyuki\|Matsumoto, Tomonori\|Ueda, Yoshihide\|Matsumoto, Yuko\|Endo, Yoko\|Takai, Atsushi\|Chiba, Tsutomu
PMID:	21469143

105.
Journal:	J Pathol. 2012 Jul;227(3):275-85.
Title:	In hepatocellular carcinoma miR-519d is up-regulated by p53 and DNA hypomethylation and targets CDKN1A/p21, PTEN, AKT3 and TIMP2.
Author:	Fornari, Francesca\|Milazzo, Maddalena\|Chieco, Pasquale\|Negrini, Massimo\|Marasco, Elena\|Capranico, Giovanni\|Mantovani, Vilma\|Marinello, Jessica\|Sabbioni, Silvia\|Callegari, Elisa\|Cescon, Matteo\|Ravaioli, Matteo\|Croce, Carlo M\|Bolondi, Luigi\|Gramantieri, Lau
PMID:	22262409

106.
Journal:	Am J Pathol. 2012 May;180(5):1798-807.
Title:	Co-expression of XIAP and cyclin D1 complex correlates with a poor prognosis in patients with hepatocellular carcinoma.
Author:	Che, Yufang\|Ye, Fei\|Xu, Ruliang\|Qing, Haitao\|Wang, Xinying\|Yin, Fei\|Cui, Miao\|Burstein, David\|Jiang, Bo\|Zhang, David Y
PMID:	22429965

107.
Journal:	PLoS One. 2012;7(4):e35331.
Title:	Role of miR-148a in hepatitis B associated hepatocellular carcinoma.
Author:	Yuan, Ke\|Lian, Zhaorui\|Sun, Bill\|Clayton, Marcia M\|Ng, Irene O L\|Feitelson, Mark A
PMID:	22496917

108.
Journal:	Oncol Rep. 2012 Jul;28(1):311-8.
Title:	SIRT1 promotes tumorigenesis of hepatocellular carcinoma through PI3K/PTEN/AKT signaling.
Author:	Wang, Hanning\|Liu, Hao\|Chen, Kaiyun\|Xiao, Jinfeng\|He, Ke\|Zhang, Jinqian\|Xiang, Guoan
PMID:	22552445

109.
Journal:	Cell Signal. 2012 Aug;24(8):1722-32.
Title:	Beclin 1-mediated autophagy in hepatocellular carcinoma cells: implication in anticancer efficiency of oroxylin A via inhibition of mTOR signaling.
Author:	Zou, Meijuan\|Lu, Na\|Hu, Chen\|Liu, Wei\|Sun, Yajing\|Wang, Xiaotang\|You, Qidong\|Gu, Cong\|Xi, Tao\|Guo, Qinglong
PMID:	22560876

110.
Journal:	Mol Cancer Res. 2012 Jul;10(7):979-91.
Title:	Human ESC self-renewal promoting microRNAs induce epithelial-mesenchymal transition in hepatocytes by controlling the PTEN and TGFbeta tumor suppressor signaling pathways.
Author:	Jung, Christine J\|Iyengar, Sushma\|Blahnik, Kimberly R\|Jiang, Joy X\|Tahimic, Candice\|Torok, Natalie J\|de vere White, Ralph W\|Farnham, Peggy J\|Zern, Mark
PMID:	22622027

111.
Journal:	Toxicol Pathol. 2012 Dec;40(8):1141-59.
Title:	Differential transcriptomic analysis of spontaneous lung tumors in B6C3F1 mice: comparison to human non-small cell lung cancer.
Author:	Pandiri, Arun R\|Sills, Robert C\|Ziglioli, Vincent\|Ton, Thai-Vu T\|Hong, Hue-Hua L\|Lahousse, Stephanie A\|Gerrish, Kevin E\|Auerbach, Scott S\|Shockley, Keith R\|Bushel, Pierre R\|Peddada, Shyamal D\|Hoenerhoff, Mark J
PMID:	22688403

112.
Journal:	Biochem Biophys Res Commun. 2012 Aug 24;425(2):169-76.
Title:	Hepatoma-derived growth factor stimulates podosome rosettes formation in NIH/3T3 cells through the activation of phosphatidylinositol 3-kinase/Akt pathway.
Author:	Kung, Mei-Lang\|Tsai, Han-En\|Hu, Tsung-Hui\|Kuo, Hsiao-Mei\|Liu, Li-Fen\|Chen, San-Cher\|Lin, Pey-Ru\|Ma, Yi-Ling\|Wang, E-Ming\|Liu, Guei-Sheung\|Liu, Jong-Kang\|Tai, Ming-Hong
PMID:	22819846

113.
Journal:	Hepatology. 2012 Dec;56(6):2255-67.
Title:	Hepatic transforming growth factor beta gives rise to tumor-initiating cells and promotes liver cancer development.
Author:	Wu, Kun\|Ding, Jin\|Chen, Cheng\|Sun, Wen\|Ning, Bei-Fang\|Wen, Wen\|Huang, Lei\|Han, Tao\|Yang, Wen\|Wang, Chao\|Li, Zhong\|Wu, Meng-Chao\|Feng, Gen-Sheng\|Xie, Wei-Fen\|Wang, Hong-Yang
PMID:	22898879

114.
Journal:	Int J Mol Sci. 2012;13(8):9980-91.
Title:	Combined phosphatase and tensin homolog (PTEN) loss and fatty acid synthase (FAS) overexpression worsens the prognosis of Chinese patients with hepatocellular carcinoma.
Author:	Zhu, Xuehua\|Qin, Xia\|Fei, Maogui\|Hou, Wenmin\|Greshock, Joel\|Bachman, Kurtis E\|Wooster, Richard\|Kang, Jiuhong\|Qin, Crystal Ying
PMID:	22949843

115.
Journal:	Mol Med Rep. 2012 Dec;6(6):1367-70.
Title:	Side-effects of resveratrol in HepG2 cells: reduced pten and increased bcl-xl mRNA expression.
Author:	Zheng, Min\|Chen, Ruifu\|Zhong, Hongyuan\|Lin, Qiuyan\|Wang, Xiaoqin\|Zhao, Zhiwei\|Xie, Linna
PMID:	22971900

116.
Journal:	J BUON. 2012 Jul-Sep;17(3):593-9.
Title:	Gene numerical imbalances in cytological specimens based on fluorescence/chromogenic in situ hybridization analysis.
Author:	Tsiambas, E\|Karameris, A\|Lygeros, M\|Athanasiou, A E\|Salemis, N S\|Gourgiotis, S\|Ragkos, V\|Metaxas, G E\|Vilaras, G\|Patsouris, E
PMID:	23033306

117.
Journal:	Int J Nanomedicine. 2012;7:5039-49.
Title:	Mannan-modified Ad5-PTEN treatment combined with docetaxel improves the therapeutic effect in H22 tumor-bearing mice.
Author:	Liu, Zhongbing\|Li, Jinwei\|Li, Juan\|Huang, Juan\|Ke, Famin\|Qi, Qiaona\|Jiang, Xing\|Zhong, Zhirong
PMID:	23055722

118.
Journal:	Hepat Mon. 2012 Oct;12(10 HCC):e7492.
Title:	The Predictive and Prognostic Significance of c-erb-B2, EGFR, PTEN, mTOR, PI3K, p27, and ERCC1 Expression in Hepatocellular Carcinoma.
Author:	Bassullu, Nuray\|Turkmen, Ilknur\|Dayangac, Murat\|Yagiz Korkmaz, Pinar\|Yasar, Reyhan\|Akyildiz, Murat\|Yaprak, Onur\|Tokat, Yaman\|Yuzer, Yildiray\|Bulbul Dogusoy, Gulen
PMID:	23162604

119.
Journal:	Oncol Res. 2012;20(2-3):113-21.
Title:	PTEN enhances the sensitivity of human hepatocellular carcinoma cells to sorafenib.
Author:	Ruan, Zhi-Ping\|Xu, Rui\|Lv, Yi\|Tian, Tao\|Wang, Wen-Juan\|Guo, Hui\|Nan, Ke-Jun
PMID:	23193917

120.
Journal:	Zhonghua Fu Chan Ke Za Zhi. 2012 Nov;47(11):839-45.
Title:	[Preliminary investigation of the expression and functions of insulin receptor isoforms in endometrial carcinoma].
Author:	Zhang, Guo\|Li, Xiao-ping\|Wang, Jian-liu\|Wei, Li-hui
PMID:	23302125

121.
Journal:	Zhonghua Wai Ke Za Zhi. 2012 Nov;50(11):1007-10.
Title:	[A study of the relationship between the mutation of PIK3CA, PTEN and the occurrence of liver metastasis of colorectal cancer: survival analysis].
Author:	Liang, Li\|Wei, Ye\|Ren, Li\|Zhong, Yun-shi\|Xu, Jian-min
PMID:	23302486

122.
Journal:	Oncogenesis. 2012 Sep 10;1:e28.
Title:	Comparative analysis of SV40 17kT and LT function in vivo demonstrates that LT's C-terminus re-programs hepatic gene expression and is necessary for tumorigenesis in the liver.
Author:	Comerford, S A\|Schultz, N\|Hinnant, E A\|Klapproth, S\|Hammer, R E
PMID:	23552841

123.
Journal:	FASEB J. 2013 Feb;27(2):632-44.
Title:	Phosphatase and tensin homolog regulates stability and activity of EphB1 receptor.
Author:	Rodriguez, Stephane\|Huynh-Do, Uyen
PMID:	23118026

124.
Journal:	Food Chem. 2013 Jan 15;136(2):659-67.
Title:	Neferine induces reactive oxygen species mediated intrinsic pathway of apoptosis in HepG2 cells.
Author:	Poornima, Paramasivan\|Quency, Robin Sheeba\|Padma, Viswandha Vijaya
PMID:	23122111

125.
Journal:	Am J Pathol. 2013 Jan;182(1):64-70.
Title:	Long intergenic noncoding RNA HOTAIR is overexpressed and regulates PTEN methylation in laryngeal squamous cell carcinoma.
Author:	Li, Dandan\|Feng, Jiapeng\|Wu, Tianyi\|Wang, Yandong\|Sun, Yanan\|Ren, Jingyuan\|Liu, Ming
PMID:	23141928

126.
Journal:	Oncol Rep. 2013 Mar;29(3):903-10.
Title:	Cyclin-dependent kinase-associated protein phosphatase is overexpressed in alcohol-related hepatocellular carcinoma and influences xenograft tumor growth.
Author:	Lin, Wey-Ran\|Lai, Ming-Wei\|Yeh, Chau-Ting
PMID:	23292002

127.
Journal:	PLoS One. 2013;8(1):e54458.
Title:	Immunopositivity for histone macroH2A1 isoforms marks steatosis-associated hepatocellular carcinoma.
Author:	Rappa, Francesca\|Greco, Azzura\|Podrini, Christine\|Cappello, Francesco\|Foti, Michelangelo\|Bourgoin, Lucie\|Peyrou, Marion\|Marino, Arianna\|Scibetta, Nunzia\|Williams, Roger\|Mazzoccoli, Gianluigi\|Federici, Massimo\|Pazienza, Valerio\|Vinciguerra, Manlio
PMID:	23372727

128.
Journal:	Gastroenterology. 2013 May;144(5):1055-65.
Title:	Akt and mTORC1 have different roles during liver tumorigenesis in mice.
Author:	Kenerson, Heidi L\|Yeh, Matthew M\|Kazami, Machiko\|Jiang, Xiuyun\|Riehle, Kimberly J\|McIntyre, Rebecca L\|Park, James O\|Kwon, Steve\|Campbell, Jean S\|Yeung, Raymond S
PMID:	23376645

129.
Journal:	J Cell Sci. 2013 Mar 15;126(Pt 6):1517-30.
Title:	Mature miR-17-5p and passenger miR-17-3p induce hepatocellular carcinoma by targeting PTEN, GalNT7 and vimentin in different signal pathways.
Author:	Shan, Sze Wan\|Fang, Ling\|Shatseva, Tatiana\|Rutnam, Zina Jeyapalan\|Yang, Xiangling\|Du, William\|Lu, Wei-Yang\|Xuan, Jim W\|Deng, Zhaoqun\|Yang, Burton B
PMID:	23418359

130.
Journal:	Hepatology. 2013 Aug;58(2):629-41.
Title:	MicroRNA-216a/217-induced epithelial-mesenchymal transition targets PTEN and SMAD7 to promote drug resistance and recurrence of liver cancer.
Author:	Xia, Hongping\|Ooi, London Lucien P J\|Hui, Kam M
PMID:	23471579

131.
Journal:	Cancer Chemother Pharmacol. 2013 May;71(5):1297-307.
Title:	Benchmarking effects of mTOR, PI3K, and dual PI3K/mTOR inhibitors in hepatocellular and renal cell carcinoma models developing resistance to sunitinib and sorafenib.
Author:	Serova, Maria\|de Gramont, Armand\|Tijeras-Raballand, Annemilai\|Dos Santos, Celia\|Riveiro, Maria Eugenia\|Slimane, Khemaies\|Faivre, Sandrine\|Raymond, Eric
PMID:	23479136

132.
Journal:	Mol Med Rep. 2013 May;7(5):1413-6.
Title:	Expression and significance of PTEN and miR-92 in hepatocellular carcinoma.
Author:	Zhao, Bin\|Zhu, Yueting\|Cui, Kai\|Gao, Jie\|Yu, Fachang\|Chen, Liang\|Li, Sheng
PMID:	23546593

133.
Journal:	Cancer Lett. 2013 Sep 1;337(2):226-36.
Title:	MicroRNA-21 suppresses PTEN and hSulf-1 expression and promotes hepatocellular carcinoma progression through AKT/ERK pathways.
Author:	Bao, Longlong\|Yan, Yan\|Xu, Can\|Ji, Weidan\|Shen, Shuwen\|Xu, Gaoya\|Zeng, Yong\|Sun, Bin\|Qian, Haihua\|Chen, Lei\|Wu, Mengchao\|Su, Changqing\|Chen, Jie
PMID:	23684551

134.
Journal:	J Nutr Metab. 2013;2013:514206.
Title:	Saturated Fatty Acid-induced cytotoxicity in liver cells does not involve phosphatase and tensin homologue deleted on chromosome 10.
Author:	Wang, Dong\|Wei, Yuren\|Frye, Melinda\|Gentile, Christopher L\|Pagliassotti, Michael J
PMID:	23691291

135.
Journal:	PLoS One. 2013 May 21;8(5):e63436.
Title:	TGF-beta signaling is often attenuated during hepatotumorigenesis, but is retained for the malignancy of hepatocellular carcinoma cells.
Author:	Mu, Xiaoxin\|Lin, Shu\|Yang, Junhua\|Chen, Chen\|Chen, Yun\|Herzig, Maryanne C\|Washburn, Kenneth\|Halff, Glenn A\|Walter, Christi A\|Sun, Beicheng\|Sun, Lu-Zhe
PMID:	23704908

136.
Journal:	Int J Oncol. 2013 Aug;43(2):661-9.
Title:	MicroRNA-21 regulates the migration and invasion of a stem-like population in hepatocellular carcinoma.
Author:	Zhou, Liang\|Yang, Zhao-Xu\|Song, Wen-Jie\|Li, Qing-Jun\|Yang, Fan\|Wang, De-Sheng\|Zhang, Ning\|Dou, Ke-Feng
PMID:	23708209

137.
Journal:	BMC Cancer. 2013 May 30;13:267.
Title:	Molecular mechanisms of action and potential biomarkers of growth inhibition of dasatinib (BMS-354825) on hepatocellular carcinoma cells.
Author:	Chang, Alex Y\|Wang, Miao
PMID:	23721490

138.
Journal:	Cancer Res. 2013 Aug 1;73(15):4722-31.
Title:	Proteomic and lipidomic signatures of lipid metabolism in NASH-associated hepatocellular carcinoma.
Author:	Muir, Kyle\|Hazim, Antonious\|He, Ying\|Peyressatre, Marion\|Kim, Do-Young\|Song, Xiaoling\|Beretta, Laura
PMID:	23749645

139.
Journal:	N Engl J Med. 2013 Jun 13;368(24):2266-76.
Title:	Oncofetal gene SALL4 in aggressive hepatocellular carcinoma.
Author:	Yong, Kol Jia\|Gao, Chong\|Lim, Joline S J\|Yan, Benedict\|Yang, Henry\|Dimitrov, Todor\|Kawasaki, Akira\|Ong, Chee Wee\|Wong, Kwong-Fai\|Lee, Sanghoon\|Ravikumar, Sharada\|Srivastava, Supriya\|Tian, Xi\|Poon, Ronnie T\|Fan, Sheung Tat\|Luk, John M\|Dan, Yock Young\|Salto
PMID:	23758232

140.
Journal:	Mutat Res. 2013 Aug 15;755(2):135-40.
Title:	Multinucleation regulated by the Akt/PTEN signaling pathway is a survival strategy for HepG2 cells.
Author:	Mukherjee, Ananda\|Misra, Sandip\|Howlett, Niall G\|Karmakar, Parimal
PMID:	23796964

141.
Journal:	Nan Fang Yi Ke Da Xue Xue Bao. 2013 Jun;33(6):804-11.
Title:	[Roles of miR-590-5p and miR-590-3p in the development of hepatocellular carcinoma].
Author:	Yang, Hongfei\|Zheng, Wenhong\|Zhao, Wentao\|Guan, Chunyan\|An, Jing
PMID:	23803188

142.
Journal:	Int J Oncol. 2013 Sep;43(3):793-802.
Title:	Overexpression of Bmi-1 contributes to the invasion and metastasis of hepatocellular carcinoma by increasing the expression of matrix metalloproteinase (MMP)2, MMP-9 and vascular endothelial growth factor via the PTEN/PI3K/Akt pathway.
Author:	Li, Xiaolei\|Yang, Zhaoxu\|Song, Wenjie\|Zhou, Liang\|Li, Qingjun\|Tao, Kaishan\|Zhou, Jingshi\|Wang, Xing\|Zheng, Zhigang\|You, Nan\|Dou, Kefeng\|Li, Haimin
PMID:	23807724

143.
Journal:	Exp Biol Med (Maywood). 2013 Aug 1;238(8):866-73.
Title:	Impaired phosphate and tension homologue deleted on chromosome 10 expression and its prognostic role in radical surgery for hepatocellular carcinoma with family aggregation resulting from hepatitis B and liver cirrhosis.
Author:	Zhong, Yuesi\|Yan, Jian\|Deng, Meihai\|Hu, Kunpeng\|Yao, Zhicheng\|Zou, Yong\|Xu, Ruiyun
PMID:	23828588

144.
Journal:	Mutat Res. 2013 Aug 15;755(2):90-9.
Title:	Somatic changes in primary liver cancer in Russia: a pilot study.
Author:	Kalinina, Olga\|Marchio, Agnes\|Urbanskii, Aleksandr I\|Tarkova, Aleksandra B\|Rebbani, Khadija\|Granov, Dmitri A\|Dejean, Anne\|Generalov, Mikhail I\|Pineau, Pascal
PMID:	23830926

145.
Journal:	J Biol Chem. 2013 Aug 30;288(35):25007-24.
Title:	Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) signaling regulates mitochondrial biogenesis and respiration via estrogen-related receptor alpha (ERRalpha).
Author:	Li, Yang\|He, Lina\|Zeng, Ni\|Sahu, Divya\|Cadenas, Enrique\|Shearn, Colin\|Li, Wei\|Stiles, Bangyan L
PMID:	23836899

146.
Journal:	Curr Diabetes Rev. 2013 Sep;9(5):382-6.
Title:	The influence of diabetes in the pathogenesis and the clinical course of hepatocellular carcinoma: recent findings and new perspectives.
Author:	Facciorusso, Antonio
PMID:	23845075

147.
Journal:	Eur J Surg Oncol. 2013 Sep;39(9):974-80.
Title:	Prognostic impact of pERK in advanced hepatocellular carcinoma patients treated with sorafenib.
Author:	Chen, D\|Zhao, P\|Li, S Q\|Xiao, W K\|Yin, X Y\|Peng, B G\|Liang, L J
PMID:	23845703

148.
Journal:	Biochem Soc Trans. 2013 Aug;41(4):917-22.
Title:	Role of PI3K, mTOR and Akt2 signalling in hepatic tumorigenesis via the control of PKM2 expression.
Author:	Nemazanyy, Ivan\|Espeillac, Catherine\|Pende, Mario\|Panasyuk, Ganna
PMID:	23863156

149.
Journal:	Bioconjug Chem. 2013 Aug 21;24(8):1387-97.
Title:	Mannan-conjugated adenovirus enhanced gene therapy effects on murine hepatocellular carcinoma cells in vitro and in vivo.
Author:	Liu, Zhongbing\|Ke, Famin\|Duan, Chenggang\|Lan, Huan\|Li, Juan\|Gao, Cen\|Li, Jinwei\|Zhong, Zhirong
PMID:	23937094

150.
Journal:	Nat Rev Gastroenterol Hepatol. 2013 Nov;10(11):656-65.
Title:	NAFLD, NASH and liver cancer.
Author:	Michelotti, Gregory A\|Machado, Mariana V\|Diehl, Anna Mae
PMID:	24080776

151.
Journal:	J Tradit Chin Med. 2013 Aug;33(4):479-85.
Title:	Jianpijiedu fang improves survival of hepatocarcinoma mice by affecting phosphatase and tensin homolog, phosphoinositide 3-kinase, and focal adhesion kinase.
Author:	Sun, Baoguo\|Meng, Jun\|Xiang, Ting\|Chen, Zexiong\|Li, Yulong\|Lu, Lisha\|Zhang, Shijun\|Chen, Xiaolin
PMID:	24187869

152.
Journal:	Zhonghua Zhong Liu Za Zhi. 2013 Oct;35(10):742-6.
Title:	[Metformin induces apoptosis in hepatocellular carcinoma Huh-7 cells in vitro and its mechanism].
Author:	Lin, Fen\|Yan, Wei\|Wen, Ting\|Wu, Guo-yang
PMID:	24378094

153.
Journal:	J Carcinog. 2013 Dec 31;12:22.
Title:	Targeted therapies in development for non-small cell lung cancer.
Author:	Reungwetwattana, Thanyanan\|Dy, Grace Kho
PMID:	24574860

154.
Journal:	Tumour Biol. 2014 Jan;35(1):303-13.
Title:	Apicidin-resistant HA22T hepatocellular carcinoma cells massively promote pro-survival capability via IGF-IR/PI3K/Akt signaling pathway activation.
Author:	Hsu, Hsi-Hsien\|Cheng, Li-Hao\|Ho, Tsung-Jung\|Kuo, Wei-Wen\|Lin, Yueh-Min\|Chen, Ming-Cheng\|Lee, Nien-Hung\|Tsai, Fuu-Jen\|Tsai, Kun-Hsi\|Huang, Chih-Yang
PMID:	23990456

155.
Journal:	Hepatology. 2014 Mar;59(3):947-57.
Title:	Liver-specific knockout of GRP94 in mice disrupts cell adhesion, activates liver progenitor cells, and accelerates liver tumorigenesis.
Author:	Chen, Wan-Ting\|Tseng, Chun-Chih\|Pfaffenbach, Kyle\|Kanel, Gary\|Luo, Biquan\|Stiles, Bangyan L\|Lee, Amy S
PMID:	24027047

156.
Journal:	Oncogene. 2014 Oct 16;33(42):4997-5005.
Title:	GRP78 as a regulator of liver steatosis and cancer progression mediated by loss of the tumor suppressor PTEN.
Author:	Chen, W-T\|Zhu, G\|Pfaffenbach, K\|Kanel, G\|Stiles, B\|Lee, A S
PMID:	24141775

157.
Journal:	Hepatology. 2014 Apr;59(4):1459-70.
Title:	Ribonucleotide reductase M2B inhibits cell migration and spreading by early growth response protein 1-mediated phosphatase and tensin homolog/Akt1 pathway in hepatocellular carcinoma.
Author:	Tian, Hua\|Ge, Chao\|Li, Hong\|Zhao, Fangyu\|Hou, Helei\|Chen, Taoyang\|Jiang, Guoping\|Xie, Haiyang\|Cui, Ying\|Yao, Ming\|Li, Jinjun
PMID:	24214128

158.
Journal:	Gut. 2014 Oct;63(10):1635-47.
Title:	PTEN antagonises Tcl1/hnRNPK-mediated G6PD pre-mRNA splicing which contributes to hepatocarcinogenesis.
Author:	Hong, Xuehui\|Song, Ruipeng\|Song, Huiwen\|Zheng, Tongsen\|Wang, Jiabei\|Liang, Yingjian\|Qi, Shuyi\|Lu, Zhaoyang\|Song, Xuan\|Jiang, Hongchi\|Liu, Lianxin\|Zhang, Zhiyong
PMID:	24352616

159.
Journal:	Mol Cancer Res. 2014 Mar;12(3):313-21.
Title:	miR-338-3p suppresses gastric cancer progression through a PTEN-AKT axis by targeting P-REX2a.
Author:	Guo, Bo\|Liu, Liying\|Yao, Jiayi\|Ma, Ruili\|Chang, Dongmin\|Li, Zongfang\|Song, Tusheng\|Huang, Chen
PMID:	24375644

160.
Journal:	Hepatology. 2014 May;59(5):1900-11.
Title:	Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) is an important protumorigenic factor in hepatocellular carcinoma.
Author:	Gutschner, Tony\|Hammerle, Monika\|Pazaitis, Nikolaos\|Bley, Nadine\|Fiskin, Evgenij\|Uckelmann, Hannah\|Heim, Andreas\|Grobeta, Matthias\|Hofmann, Nina\|Geffers, Robert\|Skawran, Britta\|Longerich, Thomas\|Breuhahn, Kai\|Schirmacher, Peter\|Muhleck, Britta\|Huttelmaier
PMID:	24395596

161.
Journal:	Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2014 Feb;30(2):147-50.
Title:	[Rosiglitazone inhibits human HepG2 cell proliferation via PI3K/PTEN/Akt signaling pathway].
Author:	Zhang, Meng\|Peng, Li\|Qiao, Zhibin\|He, Hongtao\|Zhou, Ye\|Xu, Zhuo
PMID:	24491054

162.
Journal:	Oncologist. 2014 Mar;19(3):235-42.
Title:	New routes to targeted therapy of intrahepatic cholangiocarcinomas revealed by next-generation sequencing.
Author:	Ross, Jeffrey S\|Wang, Kai\|Gay, Laurie\|Al-Rohil, Rami\|Rand, Janne V\|Jones, David M\|Lee, Hwa J\|Sheehan, Christine E\|Otto, Geoff A\|Palmer, Gary\|Yelensky, Roman\|Lipson, Doron\|Morosini, Deborah\|Hawryluk, Matthew\|Catenacci, Daniel V T\|Miller, Vincent A\|Churi, C
PMID:	24563076

163.
Journal:	PLoS One. 2014 Mar 14;9(3):e91745.
Title:	Hepatitis B virus induces cell proliferation via HBx-induced microRNA-21 in hepatocellular carcinoma by targeting programmed cell death protein4 (PDCD4) and phosphatase and tensin homologue (PTEN).
Author:	Damania, Preeti\|Sen, Bijoya\|Dar, Sadaf Bashir\|Kumar, Satendra\|Kumari, Anupama\|Gupta, Ekta\|Sarin, Shiv Kumar\|Venugopal, Senthil Kumar
PMID:	24633222

164.
Journal:	Oncol Rep. 2014 May;31(5):2252-60.
Title:	Antitumor effect of a selective COX-2 inhibitor, celecoxib, may be attributed to angiogenesis inhibition through modulating the PTEN/PI3K/Akt/HIF-1 pathway in an H(2)(2) murine hepatocarcinoma model.
Author:	Sui, Wenwen\|Zhang, Yueying\|Wang, Zhaopeng\|Wang, Zhaoxia\|Jia, Qing\|Wu, Licun\|Zhang, Weidong
PMID:	24647425

165.
Journal:	Pediatr Blood Cancer. 2014 Jul;61(7):1246-51.
Title:	A phase I trial of MK-2206 in children with refractory malignancies: a Children's Oncology Group study.
Author:	Fouladi, Maryam\|Perentesis, John P\|Phillips, Christine L\|Leary, Sarah\|Reid, Joel M\|McGovern, Renee M\|Ingle, Ashish M\|Ahern, Charlotte H\|Ames, Matthew M\|Houghton, Peter\|Doyle, L Austin\|Weigel, Brenda\|Blaney, Susan M
PMID:	24664955

166.
Journal:	Oncotarget. 2014 Mar 30;5(6):1475-90.
Title:	Celecoxib suppresses hepatoma stemness and progression by up-regulating PTEN.
Author:	Chu, Tian-Huei\|Chan, Hoi-Hung\|Kuo, Hsiao-Mei\|Liu, Li-Fen\|Hu, Tsung-Hui\|Sun, Cheuk-Kwan\|Kung, Mei-Lang\|Lin, Shih-Wei\|Wang, E-Ming\|Ma, Yi-Ling\|Cheng, Kwan-Hung\|Lai, Kwok Hung\|Wen, Zhi-Hong\|Hsu, Ping-I\|Tai, Ming-Hong
PMID:	24721996

167.
Journal:	Oncogenesis. 2014 Apr 14;3:e97.
Title:	MiRNA-99a directly regulates AGO2 through translational repression in hepatocellular carcinoma.
Author:	Zhang, J\|Jin, H\|Liu, H\|Lv, S\|Wang, B\|Wang, R\|Liu, H\|Ding, M\|Yang, Y\|Li, L\|Zhang, J\|Fu, S\|Xie, D\|Wu, M\|Zhou, W\|Qian, Q
PMID:	24732044

168.
Journal:	Cancer Biomark. 2014;14(2-3):177-84.
Title:	The prognostic value of the Na(+)/ H(+) exchanger regulatory factor 1 (NHERF1) protein in cancer.
Author:	Saponaro, Concetta\|Malfettone, Andrea\|Dell'Endice, Teresa Stefania\|Brunetti, Anna Elisabetta\|Achimas-Cadariu, Patriciu\|Paradiso, Angelo\|Mangia, Anita
PMID:	24878819

169.
Journal:	Antioxid Redox Signal. 2014 Dec 20;21(18):2498-514.
Title:	The PTEN/NRF2 axis promotes human carcinogenesis.
Author:	Rojo, Ana I\|Rada, Patricia\|Mendiola, Marta\|Ortega-Molina, Ana\|Wojdyla, Katarzyna\|Rogowska-Wrzesinska, Adelina\|Hardisson, David\|Serrano, Manuel\|Cuadrado, Antonio
PMID:	24892215

170.
Journal:	Am J Pathol. 2014 Aug;184(8):2355-64.
Title:	miR-185 inhibits hepatocellular carcinoma growth by targeting the DNMT1/PTEN/Akt pathway.
Author:	Qadir, Ximena V\|Han, Chang\|Lu, Dongdong\|Zhang, Jinqiang\|Wu, Tong
PMID:	24911372

171.
Journal:	Infect Agent Cancer. 2014 Jul 18;9:23.
Title:	Loss of nuclear PTEN in HCV-infected human hepatocytes.
Author:	Bao, Wenjie\|Florea, Liliana\|Wu, Ningbin\|Wang, Zhao\|Banaudha, Krishna\|Qian, Jason\|Houzet, Laurent\|Kumar, Rakesh\|Kumar, Ajit
PMID:	25075209

172.
Journal:	Int J Mol Med. 2014 Oct;34(4):1081-6.
Title:	Downregulation of Notch1 inhibits the invasion of human hepatocellular carcinoma HepG2 and MHCC97H cells through the regulation of PTEN and FAK.
Author:	Hu, Yan-Jian\|Li, Hong-Ying\|Qiu, Kai-Jie\|Li, Da-Chuan\|Zhou, Jia-Hui\|Hu, Yan-Hua\|Zhang, Feng-Min
PMID:	25110169

173.
Journal:	Nature. 2014 Oct 16;514(7522):380-4.
Title:	CRISPR-mediated direct mutation of cancer genes in the mouse liver.
Author:	Xue, Wen\|Chen, Sidi\|Yin, Hao\|Tammela, Tuomas\|Papagiannakopoulos, Thales\|Joshi, Nikhil S\|Cai, Wenxin\|Yang, Gillian\|Bronson, Roderick\|Crowley, Denise G\|Zhang, Feng\|Anderson, Daniel G\|Sharp, Phillip A\|Jacks, Tyler
PMID:	25119044

174.
Journal:	Oncol Lett. 2014 Sep;8(3):1249-1254.
Title:	Mutation analysis of key genes in RAS/RAF and PI3K/PTEN pathways in Chinese patients with hepatocellular carcinoma.
Author:	Hou, Wenmin\|Liu, Jibin\|Chen, Peizhan\|Wang, Hui\|Ye, Bang-Ce\|Qiang, Fulin
PMID:	25120700

175.
Journal:	Int J Clin Exp Pathol. 2014 Jun 15;7(7):4039-44. eCollection 2014.
Title:	miR-218 modulate hepatocellular carcinoma cell proliferation through PTEN/AKT/PI3K pathway and HoxA10.
Author:	Xiao, Zhong-Di\|Jiao, Chun-Yu\|Huang, Hai-Tao\|He, Li-Jia\|Zhao, Jiu-Jun\|Lu, Zhao-Yang\|Liu, Lian-Xin
PMID:	25120782

176.
Journal:	Cell Rep. 2014 Sep 25;8(6):1930-1942.
Title:	HIF-1-mediated suppression of acyl-CoA dehydrogenases and fatty acid oxidation is critical for cancer progression.
Author:	Huang, De\|Li, Tingting\|Li, Xinghua\|Zhang, Long\|Sun, Linchong\|He, Xiaoping\|Zhong, Xiuying\|Jia, Dongya\|Song, Libing\|Semenza, Gregg L\|Gao, Ping\|Zhang, Huafeng
PMID:	25242319

177.
Journal:	Cancer Cell Int. 2014 Sep 20;14(1):95.
Title:	MicroRNA-492 expression promotes the progression of hepatic cancer by targeting PTEN.
Author:	Jiang, Jianxin\|Zhang, Yi\|Yu, Chao\|Li, Zhipeng\|Pan, Yaozheng\|Sun, Chengyi
PMID:	25253996

178.
Journal:	BMC Cancer. 2014 Sep 26;14:721.
Title:	Tumor suppressor micro RNA miR-145 and onco micro RNAs miR-21 and miR-222 expressions are differentially modulated by hepatitis B virus X protein in malignant hepatocytes.
Author:	Bandopadhyay, Manikankana\|Banerjee, Arup\|Sarkar, Neelakshi\|Panigrahi, Rajesh\|Datta, Sibnarayan\|Pal, Ananya\|Singh, Shivram Prasad\|Biswas, Avik\|Chakrabarti, Shekhar\|Chakravarty, Runu
PMID:	25260533

179.
Journal:	Oncotarget. 2014 Dec 30;5(24):12916-35.
Title:	Aurora-A promotes chemoresistance in hepatocelluar carcinoma by targeting NF-kappaB/microRNA-21/PTEN signaling pathway.
Author:	Zhang, Kai\|Chen, Jing\|Chen, Dongqin\|Huang, Jiayuan\|Feng, Bing\|Han, Siqi\|Chen, Yitian\|Song, Haizhu\|De, Wei\|Zhu, Ziman\|Wang, Rui\|Chen, Longbang
PMID:	25428915

180.
Journal:	Mol Cytogenet. 2014 Nov 25;7(1):81.
Title:	Recurrent genetic alterations in hepatitis C-associated hepatocellular carcinoma detected by genomic microarray: a genetic, clinical and pathological correlation study.
Author:	Liu, Yajuan J\|Zhou, Yang\|Yeh, Matthew M
PMID:	25469175

181.
Journal:	J Exp Clin Cancer Res. 2014 Dec 14;33:105.
Title:	Overexpression of brachyury contributes to tumor metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma.
Author:	Du, Rui\|Wu, Shanshan\|Lv, Xiaoning\|Fang, Henghu\|Wu, Sudong\|Kang, Jingbo
PMID:	25499255

182.
Journal:	Zhonghua Gan Zang Bing Za Zhi. 2014 Nov;22(11):837-42.
Title:	[The anti-apoptotic effect of cytoplasmic alpha-fetoprotein in hepatoma cells induced by all-trans retinoic acid involves activation of the PI3K/AKT signaling pathway].
Author:	Zhu, Ming-Yue\|Guo, Jun-Li\|Xia, Hua\|Li, Wei\|Lu, Yan\|Dong, Xu\|Chen, Yi\|Fu, Shi-Gan\|Xie, Xie-Ju\|Li, Feng-Sen
PMID:	25531381

183.
Journal:	Int J Clin Exp Pathol. 2014 Oct 15;7(11):7351-9. eCollection 2014.
Title:	Down-regulation of PTEN by HCV core protein through activating nuclear factor-kappaB.
Author:	Zhang, Yong\|Li, Rong-Qing\|Feng, Xu-Dong\|Zhang, Yan-Hua\|Wang, Li
PMID:	25550771

184.
Journal:	Asian Pac J Cancer Prev. 2014;15(23):10085-9.
Title:	Induction of apoptosis by IGFBP3 overexpression in hepatocellular carcinoma cells.
Author:	Han, Jian-Jun\|Xue, De-Wen\|Han, Qiu-Rong\|Liang, Xiao-Hong\|Xie, Li\|Li, Sheng\|Wu, Hui-Yong\|Song, Bao
PMID:	25556430

185.
Journal:	Chemotherapy. 2014;60(2):112-8.
Title:	Combination of Matrine and Sorafenib Decreases the Aggressive Phenotypes of Hepatocellular Carcinoma Cells.
Author:	Lin, Yan\|Lin, Lianjie\|Jin, Yu\|Wang, Dongxu\|Tan, Yue\|Zheng, Changqing
PMID:	25721136

186.
Journal:	Oncogene. 2015 Feb 19;34(8):965-77.
Title:	miR-625 suppresses tumour migration and invasion by targeting IGF2BP1 in hepatocellular carcinoma.
Author:	Zhou, X\|Zhang, C Z\|Lu, S-X\|Chen, G G\|Li, L-Z\|Liu, L-L\|Yi, C\|Fu, J\|Hu, W\|Wen, J-M\|Yun, J-P
PMID:	24632613

187.
Journal:	Mol Carcinog. 2015 Oct;54(10):1194-204.
Title:	Autophagy defects suggested by low levels of autophagy activator MAP1S and high levels of autophagy inhibitor LRPPRC predict poor prognosis of prostate cancer patients.
Author:	Jiang, Xianhan\|Zhong, Weide\|Huang, Hai\|He, Huichan\|Jiang, Funeng\|Chen, Yanru\|Yue, Fei\|Zou, Jing\|Li, Xun\|He, Yongzhong\|You, Pan\|Yang, Weiqiang\|Lai, Yiming\|Wang, Fen\|Liu, Leyuan
PMID:	25043940

188.
Journal:	Oncogene. 2015 Jun;34(25):3273-82.
Title:	TGF-beta signaling alters the pattern of liver tumorigenesis induced by Pten inactivation.
Author:	Morris, S M\|Carter, K T\|Baek, J Y\|Koszarek, A\|Yeh, M M\|Knoblaugh, S E\|Grady, W M
PMID:	25132272

189.
Journal:	J Appl Toxicol. 2015 May;35(5):485-92.
Title:	Carnosic acid induces autophagic cell death through inhibition of the Akt/mTOR pathway in human hepatoma cells.
Author:	Gao, Qilong\|Liu, Huaimin\|Yao, Yamin\|Geng, Liang\|Zhang, Xinfeng\|Jiang, Lifeng\|Shi, Bian\|Yang, Feng
PMID:	25178877

190.
Journal:	J Hepatol. 2015 Feb;62(2):421-9.
Title:	Hepatic PTEN deficiency improves muscle insulin sensitivity and decreases adiposity in mice.
Author:	Peyrou, Marion\|Bourgoin, Lucie\|Poher, Anne-Laure\|Altirriba, Jordi\|Maeder, Christine\|Caillon, Aurelie\|Fournier, Margot\|Montet, Xavier\|Rohner-Jeanrenaud, Francoise\|Foti, Michelangelo
PMID:	25234947

191.
Journal:	Tumour Biol. 2015 Mar;36(3):1511-8.
Title:	Overexpression of miR-218 inhibits hepatocellular carcinoma cell growth through RET.
Author:	Sui, Chengjun\|Xu, Feng\|Shen, Weifeng\|Geng, Li\|Xie, Feng\|Dai, Binghua\|Lu, Jiongjiong\|Zhang, Minfeng\|Yang, Jiamei
PMID:	25374061

192.
Journal:	Oncol Rep. 2015 Jan;33(1):201-6.
Title:	DJ-1 knockdown inhibits growth and xenograftinduced tumor generation of human hepatocellular carcinoma cells.
Author:	Liu, Shunfang\|Long, Guoxian\|Wei, Honglan\|Shi, Lei\|Yang, Zhifang\|Liu, Dongbo\|Hu, Guoqing\|Qiu, Hong
PMID:	25384406

193.
Journal:	Liver Int. 2015 Jun;35(6):1682-91.
Title:	Hepatitis C virus NS5A drives a PTEN-PI3K/Akt feedback loop to support cell survival.
Author:	Cheng, Du\|Zhang, Leiliang\|Yang, Guangbo\|Zhao, Lei\|Peng, Feng\|Tian, Yi\|Xiao, Xinqiang\|Chung, Raymond T\|Gong, Guozhong
PMID:	25388655

194.
Journal:	Horm Metab Res. 2015 Mar;47(3):168-75.
Title:	Leptin improves fatty liver independently of insulin sensitization and appetite suppression in hepatocyte-specific Pten-deficient mice with insulin hypersensitivity.
Author:	Yamamoto-Kataoka, S\|Ebihara, K\|Aizawa-Abe, M\|Nishio, M\|Kusakabe, T\|Yamamoto, Y\|Aotani, D\|Sakai, T\|Zhao, M\|Ebihara, C\|Gumbilai, V M J\|Hosoda, K\|Suzuki, A\|Nakao, K
PMID:	25415231

195.
Journal:	Adv Exp Med Biol. 2015;815:173-84.
Title:	Understanding the tumor suppressor PTEN in chronic alcoholism and hepatocellular carcinoma.
Author:	Shearn, Colin T\|Petersen, Dennis R
PMID:	25427907

196.
Journal:	Biochim Biophys Acta. 2015 Jan;1853(1):244-53.
Title:	Indole-3-carbinol inhibits tumorigenicity of hepatocellular carcinoma cells via suppression of microRNA-21 and upregulation of phosphatase and tensin homolog.
Author:	Wang, Xinmei\|He, Hongyan\|Lu, Yuanzhi\|Ren, Wei\|Teng, Kun-Yu\|Chiang, Chi-Ling\|Yang, Zhaogang\|Yu, Bo\|Hsu, Shuhao\|Jacob, Samson T\|Ghoshal, Kalpana\|Lee, L James
PMID:	25447674

197.
Journal:	J Invest Dermatol. 2015 Apr;135(4):960-969.
Title:	miR-214 as a key hub that controls cancer networks: small player, multiple functions.
Author:	Penna, Elisa\|Orso, Francesca\|Taverna, Daniela
PMID:	25501033

198.
Journal:	Oncol Rep. 2015 Mar;33(3):1493-8.
Title:	STAT3 regulates the migration and invasion of a stemlike subpopulation through microRNA21 and multiple targets in hepatocellular carcinoma.
Author:	Zhang, Ning\|Duan, Wei-Dong\|Leng, Jian-Jun\|Zhou, Liang\|Wang, Xing\|Xu, Yin-Zhe\|Wang, Xue-Dong\|Zhang, Ai-Qun\|Dong, Jia-Hong
PMID:	25571964

199.
Journal:	Pathol Res Pract. 2015 Apr;211(4):316-9.
Title:	PTEN and hTERT gene expression and the correlation with human hepatocellular carcinoma.
Author:	Zhou, Xu\|Zhu, Huaqiang\|Lu, Jun
PMID:	25613699

200.
Journal:	Biomaterials. 2015 Mar;44:71-81.
Title:	Suppression of hepatocellular carcinoma by baculovirus-mediated expression of long non-coding RNA PTENP1 and MicroRNA regulation.
Author:	Chen, Chiu-Ling\|Tseng, Yen-Wen\|Wu, Jaw-Ching\|Chen, Guan-Yu\|Lin, Kuan-Chen\|Hwang, Shiaw-Min\|Hu, Yu-Chen
PMID:	25617127

201.
Journal:	J Hepatol. 2015 Jun;62(6):1296-303.
Title:	Regular exercise decreases liver tumors development in hepatocyte-specific PTEN-deficient mice independently of steatosis.
Author:	Piguet, Anne-Christine\|Saran, Uttara\|Simillion, Cedric\|Keller, Irene\|Terracciano, Luigi\|Reeves, Helen L\|Dufour, Jean-Francois
PMID:	25623824

202.
Journal:	Oncotarget. 2015 Feb 20;6(5):3211-24.
Title:	MicroRNA-93 activates c-Met/PI3K/Akt pathway activity in hepatocellular carcinoma by directly inhibiting PTEN and CDKN1A.
Author:	Ohta, Katsuya\|Hoshino, Hiromitsu\|Wang, Jinhua\|Ono, Shigeshi\|Iida, Yuuki\|Hata, Keisuke\|Huang, Sharon K\|Colquhoun, Steven\|Hoon, Dave S B
PMID:	25633810

203.
Journal:	Virol J. 2015 Feb 3;12:12.
Title:	Inhibition of IRS-1 by hepatitis C virus infection leads to insulin resistance in a PTEN-dependent manner.
Author:	Gao, Ting-ting\|Qin, Zhao-ling\|Ren, Hao\|Zhao, Ping\|Qi, Zhong-tian
PMID:	25645159

204.
Journal:	Tumour Biol. 2015 Jun;36(6):4747-55.
Title:	MiR-32 induces cell proliferation, migration, and invasion in hepatocellular carcinoma by targeting PTEN.
Author:	Yan, Shi-Yan\|Chen, Mei-Mei\|Li, Guang-Ming\|Wang, Yu-Qin\|Fan, Jian-Gao
PMID:	25647261

205.
Journal:	Oncotarget. 2015 Mar 20;6(8):6014-28.
Title:	miR-1236 down-regulates alpha-fetoprotein, thus causing PTEN accumulation, which inhibits the PI3K/Akt pathway and malignant phenotype in hepatoma cells.
Author:	Gao, Rui\|Cai, Chunli\|Gan, Jiancheng\|Yang, Xi\|Shuang, Zeyu\|Liu, Min\|Li, Shengping\|Tang, Hua
PMID:	25714026

206.
Journal:	Cancer Res. 2015 May 1;75(9):1859-67.
Title:	miR-21 Inhibition Reduces Liver Fibrosis and Prevents Tumor Development by Inducing Apoptosis of CD24+ Progenitor Cells.
Author:	Zhang, Jing\|Jiao, Jingjing\|Cermelli, Silvia\|Muir, Kyle\|Jung, Kwang Hwa\|Zou, Ruhai\|Rashid, Asif\|Gagea, Mihai\|Zabludoff, Sonya\|Kalluri, Raghu\|Beretta, Laura
PMID:	25769721

207.
Journal:	Oncoscience. 2015 Jan 6;2(1):59-70. eCollection 2015.
Title:	Alpha-fetoprotein activates AKT/mTOR signaling to promote CXCR4 expression and migration of hepatoma cells.
Author:	Zhu, Mingyue\|Guo, Junli\|Xia, Hua\|Li, Wei\|Lu, Yan\|Dong, Xu\|Chen, Yi\|Xie, Xieju\|Fu, Shigan\|Li, Mengsen
PMID:	25815363

208.
Journal:	Gastrointest Cancer. 2015 Feb 1;5:61-71.
Title:	Von Hippel-Lindau status influences phenotype of liver cancers arising from PTEN loss.
Author:	Sendor, Adam B\|Hacker, Kathryn E\|Chen, Shufen\|Corona, Armando L\|Sen, Oishee\|Chiang, Derek Y\|Snavely, Anna\|Rogers, Arlin B\|Montgomery, Stephanie A\|Rathmell, W Kimryn\|McRee, Autumn J
PMID:	25844041

209.
Journal:	PLoS One. 2015 Apr 7;10(4):e0121298.
Title:	Evaluation of the medicinal herb Graptopetalum paraguayense as a treatment for liver cancer.
Author:	Hsu, Wei-Hsiang\|Chang, Chia-Chuan\|Huang, Kai-Wen\|Chen, Yi-Chen\|Hsu, Shih-Lan\|Wu, Li-Chen\|Tsou, Ann-Ping\|Lai, Jin-Mei\|Huang, Chi-Ying F
PMID:	25849560

210.
Journal:	Chin Med J (Engl). 2015 Apr 20;128(8):1005-13.
Title:	Phosphatase and tensin homologue genetic polymorphisms and their interactions with viral mutations on the risk of hepatocellular carcinoma.
Author:	Du, Yan\|Zhang, Yu-Wei\|Pu, Rui\|Han, Xue\|Hu, Jian-Ping\|Zhang, Hong-Wei\|Wang, Hong-Yang\|Cao, Guang-Wen
PMID:	25881591

211.
Journal:	Oncotarget. 2015 May 20;6(14):12723-39.
Title:	JARID1B promotes metastasis and epithelial-mesenchymal transition via PTEN/AKT signaling in hepatocellular carcinoma cells.
Author:	Tang, Bo\|Qi, Guangying\|Tang, Fang\|Yuan, Shengguang\|Wang, Zhenran\|Liang, Xingsi\|Li, Bo\|Yu, Shuiping\|Liu, Jie\|Huang, Qi\|Wei, Yangchao\|Zhai, Run\|Lei, Biao\|Yu, Hongping\|Jiao, Xingyuan\|He, Songqing
PMID:	25909289

212.
Journal:	Cancer Lett. 2015 Aug 1;364(1):33-43.
Title:	MiR-429 increases the metastatic capability of HCC via regulating classic Wnt pathway rather than epithelial-mesenchymal transition.
Author:	Tang, Jing\|Li, Liang\|Huang, Wentao\|Sui, Chengjun\|Yang, Yingcheng\|Lin, Ximeng\|Hou, Guojun\|Chen, Xin\|Fu, Jing\|Yuan, Shengxian\|Li, Shao\|Wen, Wen\|Tang, Shanhua\|Cao, Dan\|Wu, Mengchao\|Chen, Lei\|Wang, Hongyang
PMID:	25931210

213.
Journal:	Acta Pharmacol Sin. 2015 Oct;36(10):1237-45.
Title:	Argonaute 2 promotes angiogenesis via the PTEN/VEGF signaling pathway in human hepatocellular carcinoma.
Author:	Ye, Zhen-long\|Huang, Yao\|Li, Lin-fang\|Zhu, Hai-li\|Gao, Hai-xia\|Liu, Hui\|Lv, Sai-qun\|Xu, Zeng-hui\|Zheng, Luo-ning\|Liu, Tao\|Zhang, Jing-lei\|Jin, Hua-jun\|Qian, Qi-jun
PMID:	25937637

214.
Journal:	Int J Clin Exp Pathol. 2015 Feb 1;8(2):1466-78. eCollection 2015.
Title:	Significance of serum microRNA-21 in diagnosis of hepatocellular carcinoma (HCC): clinical analyses of patients and an HCC rat model.
Author:	Wang, Xing\|Zhang, Juan\|Zhou, Liang\|Lu, Peng\|Zheng, Zhi-Gang\|Sun, Wei\|Wang, Jian-Lin\|Yang, Xi-Sheng\|Li, Xiao-Lei\|Xia, Ning\|Zhang, Ning\|Dou, Ke-Feng
PMID:	25973032

215.
Journal:	Int J Radiat Oncol Biol Phys. 2015 Aug 1;92(5):1132-1140.
Title:	MiR-20a Induces Cell Radioresistance by Activating the PTEN/PI3K/Akt Signaling Pathway in Hepatocellular Carcinoma.
Author:	Zhang, Yuqin\|Zheng, Lin\|Ding, Yi\|Li, Qi\|Wang, Rong\|Liu, Tongxin\|Sun, Quanquan\|Yang, Hua\|Peng, Shunli\|Wang, Wei\|Chen, Longhua
PMID:	26031366

216.
Journal:	Oncol Rep. 2015 Aug;34(2):1003-10.
Title:	miR-494 promotes cell proliferation, migration and invasion, and increased sorafenib resistance in hepatocellular carcinoma by targeting PTEN.
Author:	Liu, Kai\|Liu, Songyang\|Zhang, Wei\|Jia, Baoxing\|Tan, Ludong\|Jin, Zhe\|Liu, Yahui
PMID:	26045065

217.
Journal:	Oncotarget. 2015 Sep 15;6(27):23776-92.
Title:	3'3-Diindolylmethane inhibits migration, invasion and metastasis of hepatocellular carcinoma by suppressing FAK signaling.
Author:	Li, Wen-Xue\|Chen, Li-Ping\|Sun, Min-Ying\|Li, Jun-Tao\|Liu, Hua-Zhang\|Zhu, Wei
PMID:	26068982

218.
Journal:	Biomed Res Int. 2015;2015:256916.
Title:	Molecular Analysis of AFP and HSA Interactions with PTEN Protein.
Author:	Zhu, Mingyue\|Lin, Bo\|Zhou, Peng\|Li, Mengsen
PMID:	26078940

219.
Journal:	Infect Agent Cancer. 2015 Jul 27;10:24.
Title:	HCV infection-associated hepatocellular carcinoma in humanized mice.
Author:	Wang, Zhao\|Wu, Ningbin\|Tesfaye, Abeba\|Feinstone, Stephen\|Kumar, Ajit
PMID:	26217396

220.
Journal:	Int J Nanomedicine. 2015 Jul 29;10:4825-36.
Title:	Targeted delivery of chemically modified anti-miR-221 to hepatocellular carcinoma with negatively charged liposomes.
Author:	Zhang, Wendian\|Peng, Fangqi\|Zhou, Taotao\|Huang, Yifei\|Zhang, Li\|Ye, Peng\|Lu, Miao\|Yang, Guang\|Gai, Yongkang\|Yang, Tan\|Ma, Xiang\|Xiang, Guangya
PMID:	26251599

221.
Journal:	Cancer Lett. 2015 Nov 1;368(1):126-34.
Title:	Matrine derivative WM130 inhibits hepatocellular carcinoma by suppressing EGFR/ERK/MMP-2 and PTEN/AKT signaling pathways.
Author:	Qian, Liqiang\|Liu, Yan\|Xu, Yang\|Ji, Weidan\|Wu, Qiuye\|Liu, Yongjing\|Gao, Quangen\|Su, Changqing
PMID:	26259512

222.
Journal:	Int J Mol Sci. 2015 Aug 17;16(8):19419-32.
Title:	Lentiviral-Mediated Short Hairpin RNA Knockdown of MTDH Inhibits Cell Growth and Induces Apoptosis by Regulating the PTEN/AKT Pathway in Hepatocellular Carcinoma.
Author:	Li, Wen-Fang\|Ou, Qin\|Dai, Hang\|Liu, Chang-An
PMID:	26287185

223.
Journal:	Oncotarget. 2015 Oct 6;6(30):28867-81.
Title:	MiR-21 mediates sorafenib resistance of hepatocellular carcinoma cells by inhibiting autophagy via the PTEN/Akt pathway.
Author:	He, Changjun\|Dong, Xuesong\|Zhai, Bo\|Jiang, Xian\|Dong, Deli\|Li, Baoxin\|Jiang, Hongchi\|Xu, Shidong\|Sun, Xueying
PMID:	26311740

224.
Journal:	Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):13982-7.
Title:	CRISPR/Cas9 somatic multiplex-mutagenesis for high-throughput functional cancer genomics in mice.
Author:	Weber, Julia\|Ollinger, Rupert\|Friedrich, Mathias\|Ehmer, Ursula\|Barenboim, Maxim\|Steiger, Katja\|Heid, Irina\|Mueller, Sebastian\|Maresch, Roman\|Engleitner, Thomas\|Gross, Nina\|Geumann, Ulf\|Fu, Beiyuan\|Segler, Angela\|Yuan, Detian\|Lange, Sebastian\|Strong, Alexa
PMID:	26508638

225.
Journal:	Oncotarget. 2015 Dec 1;6(38):40775-98.
Title:	CUDR promotes liver cancer stem cell growth through upregulating TERT and C-Myc.
Author:	Pu, Hu\|Zheng, Qidi\|Li, Haiyan\|Wu, Mengying\|An, Jiahui\|Gui, Xin\|Li, Tianming\|Lu, Dongdong
PMID:	26513297

226.
Journal:	Medicine (Baltimore). 2015 Nov;94(44):e1806.
Title:	COX-2 Promotes Migration and Invasion by the Side Population of Cancer Stem Cell-Like Hepatocellular Carcinoma Cells.
Author:	Guo, Zhe\|Jiang, Jing-Hang\|Zhang, Jun\|Yang, Hao-Jie\|Yang, Fu-Quan\|Qi, Ya-Peng\|Zhong, Yan-Ping\|Su, Jie\|Yang, Ri-Rong\|Li, Le-Qun\|Xiang, Bang-De
PMID:	26554780

227.
Journal:	Int J Clin Exp Pathol. 2015 Nov 1;8(11):15198-203. eCollection 2015.
Title:	Association of PTEN gene polymorphisms with liver cancer risk.
Author:	Li, Hong-Guang\|Liu, Fang-Feng\|Zhu, Hua-Qiang\|Zhou, Xu\|Lu, Jun\|Chang, Hong\|Hu, Jin-Hua
PMID:	26823866

228.
Journal:	Eur J Cancer Prev. 2016 Jan;25(1):54-64.
Title:	Synergic chemoprevention with dietary carbohydrate restriction and supplementation of AMPK-activating phytochemicals: the role of SIRT1.
Author:	Lee, Jong Doo\|Choi, Min-Ah\|Ro, Simon Weonsang\|Yang, Woo Ick\|Cho, Arthur E H\|Ju, Hye-Lim\|Baek, Sinhwa\|Chung, Sook In\|Kang, Won Jun\|Yun, Mijin\|Park, Jeon Han
PMID:	25747515

229.
Journal:	Tumour Biol. 2016 Feb;37(2):2691-702.
Title:	Long noncoding RNA GAS5 suppresses the migration and invasion of hepatocellular carcinoma cells via miR-21.
Author:	Hu, Litian\|Ye, Hua\|Huang, Guangming\|Luo, Fei\|Liu, Yawei\|Liu, Yi\|Yang, Xiaojun\|Shen, Jian\|Liu, Qizhan\|Zhang, Jianping
PMID:	26404135

230.
Journal:	Oncol Rep. 2016 Jan;35(1):366-74.
Title:	MicroRNA-616 promotes the migration, invasion and epithelial-mesenchymal transition of HCC by targeting PTEN.
Author:	Zhang, Di\|Zhou, Peihua\|Wang, Wei\|Wang, Xiaolong\|Li, Junhui\|Sun, Xuejun\|Zhang, Li
PMID:	26499912

231.
Journal:	J Gastroenterol. 2016 May;51(5):473-86.
Title:	Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features.
Author:	Kawai-Kitahata, Fukiko\|Asahina, Yasuhiro\|Tanaka, Shinji\|Kakinuma, Sei\|Murakawa, Miyako\|Nitta, Sayuri\|Watanabe, Takako\|Otani, Satoshi\|Taniguchi, Miki\|Goto, Fumio\|Nagata, Hiroko\|Kaneko, Shun\|Tasaka-Fujita, Megumi\|Nishimura-Sakurai, Yuki\|Azuma, Seishin\|Itsui
PMID:	26553052

232.
Journal:	Tumour Biol. 2016 May;37(5):5885-95.
Title:	Overexpression of microRNA-30a-5p inhibits liver cancer cell proliferation and induces apoptosis by targeting MTDH/PTEN/AKT pathway.
Author:	Li, Wen-Fang\|Dai, Hang\|Ou, Qin\|Zuo, Guo-Qing\|Liu, Chang-An
PMID:	26589417

233.
Journal:	Gastroenterology. 2016 Mar;150(3):720-33.
Title:	Epithelial Transforming Growth Factor-beta Signaling Does Not Contribute to Liver Fibrosis but Protects Mice From Cholangiocarcinoma.
Author:	Mu, Xueru\|Pradere, Jean-Philippe\|Affo, Silvia\|Dapito, Dianne H\|Friedman, Richard\|Lefkovitch, Jay H\|Schwabe, Robert F
PMID:	26627606

234.
Journal:	J Surg Oncol. 2016 Jan;113(1):55-61.
Title:	Comprehensive multiplatform biomarker analysis of 350 hepatocellular carcinomas identifies potential novel therapeutic options.
Author:	Ang, Celina\|Miura, John T\|Gamblin, T Clark\|He, Ruth\|Xiu, Joanne\|Millis, Sherri Z\|Gatalica, Zoran\|Reddy, Sandeep K\|Yee, Nelson S\|Abou-Alfa, Ghassan K
PMID:	26661118

235.
Journal:	Int J Oncol. 2016 Mar;48(3):965-74.
Title:	MicroRNA-519a promotes tumor growth by targeting PTEN/PI3K/AKT signaling in hepatocellular carcinoma.
Author:	Tu, Kangsheng\|Liu, Zhikui\|Yao, Bowen\|Han, Shaoshan\|Yang, Wei
PMID:	26708293

236.
Journal:	Oncol Rep. 2016 Mar;35(3):1403-8.
Title:	Expression and mechanism of microRNA-181A on incidence and survival in late liver metastases of colorectal cancer.
Author:	Li, Zengjun\|Wang, Haipeng\|Xu, Zhongfa\|Sun, Yanlai\|Han, Jianjun
PMID:	26750720

237.
Journal:	Biochem Biophys Res Commun. 2016 Jan 29;470(1):187-191.
Title:	miR-367 promotes proliferation and invasion of hepatocellular carcinoma cells by negatively regulating PTEN.
Author:	Meng, Xiangrui\|Lu, Peng\|Fan, Qingxia
PMID:	26772880

238.
Journal:	Cell Cycle. 2016;15(4):573-83.
Title:	A PTEN inhibitor displays preclinical activity against hepatocarcinoma cells.
Author:	Augello, Giuseppa\|Puleio, Roberto\|Emma, Maria Rita\|Cusimano, Antonella\|Loria, Guido R\|McCubrey, James A\|Montalto, Giuseppe\|Cervello, Melchiorre
PMID:	26794644

239.
Journal:	Tumour Biol. 2016 Aug;37(8):10085-96.
Title:	A novel anti-alpha-fetoprotein single-chain variable fragment displays anti-tumor effects in HepG2 cells as a single agent or in combination with paclitaxel.
Author:	Ji, Xiaonan\|Shen, Yanli\|Sun, Hao\|Gao, Xiangdong
PMID:	26820129

240.
Journal:	BMC Complement Altern Med. 2016 Feb 9;16:58.
Title:	Polyphyllin VII induces apoptosis in HepG2 cells through ROS-mediated mitochondrial dysfunction and MAPK pathways.
Author:	Zhang, Chao\|Jia, Xuejing\|Bao, Jiaolin\|Chen, Shenghui\|Wang, Kai\|Zhang, Yulin\|Li, Peng\|Wan, Jian-Bo\|Su, Huanxing\|Wang, Yitao\|Mei, Zhinan\|He, Chengwei
PMID:	26861252

241.
Journal:	Phytomedicine. 2016 Jan 15;23(1):42-51.
Title:	Liver cancer cells are sensitive to Lanatoside C induced cell death independent of their PTEN status.
Author:	Durmaz, Irem\|Guven, Ebru Bilget\|Ersahin, Tulin\|Ozturk, Mehmet\|Calis, Ihsan\|Cetin-Atalay, Rengul
PMID:	26902406

242.
Journal:	Hepatology. 2016 Jun;63(6):1928-42.
Title:	MAF1 suppresses AKT-mTOR signaling and liver cancer through activation of PTEN transcription.
Author:	Li, Yue\|Tsang, Chi Kwan\|Wang, Suihai\|Li, Xiao-Xing\|Yang, Yang\|Fu, Liwu\|Huang, Wenlin\|Li, Ming\|Wang, Hui-Yun\|Zheng, X F Steven
PMID:	26910647

243.
Journal:	Hepatol Res. 2016 Dec;46(13):1380-1391.
Title:	Associations of components of PTEN/AKT/mTOR pathway with cancer stem cell markers and prognostic value of these biomarkers in hepatocellular carcinoma.
Author:	Su, Rujuan\|Nan, Haocheng\|Guo, Hui\|Ruan, Zhiping\|Jiang, Lili\|Song, Yuanyuan\|Nan, Kejun
PMID:	26932478

244.
Journal:	Curr Pharm Des. 2016;22(34):5257-5269.
Title:	Circulating microRNAs in Hepatocellular Carcinoma: Potential Diagnostic and Prognostic Biomarkers.
Author:	Mirzaei, Hamid Reza\|Sahebkar, Amirhossein\|Mohammadi, Mohsen\|Yari, Reza\|Salehi, Hossein\|Jafari, Mohammad Hasan\|Namdar, Afshin\|Khabazian, Ehsan\|Jaafari, Mahmoud Reza\|Mirzaei, Hamed
PMID:	26935703

245.
Journal:	FEBS J. 2016 May;283(10):1935-46.
Title:	MicroRNA 152 regulates hepatic glycogenesis by targeting PTEN.
Author:	Wang, Shuyue\|Wang, Lilin\|Dou, Lin\|Guo, Jun\|Fang, Weiwei\|Li, Meng\|Meng, Xiangyu\|Man, Yong\|Shen, Tao\|Huang, Xiuqing\|Li, Jian
PMID:	26996529

246.
Journal:	Oncol Lett. 2016 Mar;11(3):2223-2228.
Title:	Upregulation of PREX2 promotes the proliferation and migration of hepatocellular carcinoma cells via PTEN-AKT signaling.
Author:	He, Shujie\|Lin, Juan\|Yu, Shaoping\|Sun, Shijie
PMID:	26998152

247.
Journal:	J Biol Chem. 2016 May 27;291(22):11504-17.
Title:	Toll-like Receptor 4 on Macrophage Promotes the Development of Steatohepatitis-related Hepatocellular Carcinoma in Mice.
Author:	Miura, Kouichi\|Ishioka, Mitsuaki\|Minami, Shinichiro\|Horie, Yasuo\|Ohshima, Shigetoshi\|Goto, Takashi\|Ohnishi, Hirohide
PMID:	27022031

248.
Journal:	J Hepatol. 2016 Aug;65(2):296-304.
Title:	Integrative biomarker analyses indicate etiological variations in hepatocellular carcinoma.
Author:	Zhu, Andrew X\|Chen, David\|He, Wei\|Kanai, Masayuki\|Voi, Maurizio\|Chen, Li-Tzong\|Daniele, Bruno\|Furuse, Junji\|Kang, Yoon-Koo\|Poon, Ronnie T P\|Vogel, Arndt\|Chiang, Derek Y
PMID:	27130844

249.
Journal:	J Transl Med. 2016 May 5;14(1):122.
Title:	MiR-19a, miR-122 and miR-223 are differentially regulated by hepatitis B virus X protein and involve in cell proliferation in hepatoma cells.
Author:	Yu, Guifang\|Chen, Xuezhu\|Chen, Shudi\|Ye, Weipeng\|Hou, Kailian\|Liang, Min
PMID:	27150195

250.
Journal:	Genet Mol Res. 2016 May 9;15(2). pii: gmr8120.
Title:	Effect of overexpression of PTEN on apoptosis of liver cancer cells.
Author:	Li, M F\|Guan, H\|Zhang, D D
PMID:	27173355

251.
Journal:	Am J Transl Res. 2016 Mar 15;8(3):1302-18. eCollection 2016.
Title:	Human lung cancer-derived microparticles enhanced angiogenesis and growth of hepatoma cells in rodent lung parenchyma.
Author:	Ko, Sheung-Fat\|Hsu, Shu-Yuan\|Chen, Chih-Hung\|Sung, Pei-Hsun\|Zhen, Meng-Shen TongYen-Yi\|Chen, Yi-Ling\|Huang, Tien-Hung\|Chen, Sheng-Yi\|Kao, Gour-Shenq\|Chen, Hong-Hwa\|Chang, Chia-Lo\|Sun, Cheuk-Kwan\|Chang, Hsueh-Wen\|Yip, Hon-Kan
PMID:	27186261

252.
Journal:	Oncotarget. 2016 Jun 28;7(26):40266-40284.
Title:	JARID2 promotes invasion and metastasis of hepatocellular carcinoma by facilitating epithelial-mesenchymal transition through PTEN/AKT signaling.
Author:	Lei, Xiong\|Xu, Jiang-Feng\|Chang, Rui-Min\|Fang, Feng\|Zuo, Chao-Hui\|Yang, Lian-Yue
PMID:	27259236

253.
Journal:	Fibrogenesis Tissue Repair. 2016 Jun 14;9:8.
Title:	Activation of hepatic stellate cell in Pten null liver injury model.
Author:	He, Lina\|Gubbins, James\|Peng, Zhechu\|Medina, Vivian\|Fei, Fan\|Asahina, Kinji\|Wang, Jiaohong\|Kahn, Michael\|Rountree, Carl B\|Stiles, Bangyan L
PMID:	27307790

254.
Journal:	Oncotarget. 2016 Jul 19;7(29):46230-46241.
Title:	Metformin mediates resensitivity to 5-fluorouracil in hepatocellular carcinoma via the suppression of YAP.
Author:	Tian, Yu\|Tang, Bo\|Wang, Chengye\|Sun, Deguang\|Zhang, Rixin\|Luo, Nan\|Han, Zhao\|Liang, Rui\|Gao, Zhenming\|Wang, Liming
PMID:	27323827

255.
Journal:	Chem Biol Interact. 2016 Aug 25;256:55-63.
Title:	Utilization of metabonomics to identify serum biomarkers in murine H22 hepatocarcinoma and deduce antitumor mechanism of Rhizoma Paridis saponins.
Author:	Qiu, Peiyu\|Man, Shuli\|Yang, He\|Fan, Wei\|Yu, Peng\|Gao, Wenyuan
PMID:	27369806

256.
Journal:	Acta Biochim Biophys Sin (Shanghai). 2016 Aug;48(8):704-13.
Title:	Adenovirus-mediated co-expression of ING4 and PTEN cooperatively enhances their antitumor activity in human hepatocellular carcinoma cells.
Author:	Rakshit, Nargis\|Yang, Sijun\|Zhou, Wei\|Xu, Yi\|Deng, Chenghui\|Yang, Jiecheng\|Yu, Huijun\|Wei, Wenxiang
PMID:	27421660

257.
Journal:	Cell Physiol Biochem. 2016;39(2):768-79.
Title:	NEDD4 Depletion Inhibits Hepatocellular Carcinoma Growth via Targeting PTEN.
Author:	Hang, Xiaofeng\|Zhu, Shanbang\|Di, Hongwei\|Wu, Zhiqin\|Chu, Kaijian\|Wang, Junxue\|Xin, Haiguang\|Yu, Guanzhen\|Peng, Haoran\|Miao, Xiaohui\|Xu, Wensheng
PMID:	27467187

258.
Journal:	Med J Islam Repub Iran. 2016 May 29;30:378. eCollection 2016.
Title:	Does PTEN gene mutation play any role in Li-Fraumeni syndrome.
Author:	Akouchekian, Mansoureh\|Hemati, Simin\|Jafari, Davood\|Jalilian, Nazanin\|Dehghan Manshadi, Masoumeh
PMID:	27493922

259.
Journal:	Oncol Rep. 2016 Oct;36(4):2184-92.
Title:	Clinical effects of miR-101 on prognosis of hepatocellular carcinoma and carcinogenic mechanism of anti-miR-101.
Author:	Lv, Xuecheng\|Li, Jinghua\|Yang, Bingnan
PMID:	27498785

260.
Journal:	Oncol Rep. 2016 Oct;36(4):1819-28.
Title:	PRL-3 promotes the peritoneal metastasis of gastric cancer through the PI3K/Akt signaling pathway by regulating PTEN.
Author:	Xiong, Jianbo\|Li, Zhengrong\|Zhang, Yang\|Li, Daojiang\|Zhang, Guoyang\|Luo, Xianshi\|Jie, Zhigang\|Liu, Yi\|Cao, Yi\|Le, Zhibiao\|Tan, Shengxing\|Zou, Wenyu\|Gong, Peitao\|Qiu, Lingyu\|Li, Yuanyuan\|Wang, Huan\|Chen, Heping
PMID:	27572739

261.
Journal:	Oncotarget. 2016 Nov 8;7(45):72908-72922.
Title:	Genomic characterization of liver metastases from colorectal cancer patients.
Author:	Sayagues, Jose Maria\|Corchete, Luis Antonio\|Gutierrez, Maria Laura\|Sarasquete, Maria Eugenia\|Del Mar Abad, Maria\|Bengoechea, Oscar\|Ferminan, Encarna\|Anduaga, Maria Fernanda\|Del Carmen, Sofia\|Iglesias, Manuel\|Esteban, Carmen\|Angoso, Maria\|Alcazar, Jose Ant
PMID:	27662660

262.
Journal:	Oncotarget. 2016 Nov 8;7(45):73257-73269.
Title:	An artificial lncRNA targeting multiple miRNAs overcomes sorafenib resistance in hepatocellular carcinoma cells.
Author:	Tang, Shuyao\|Tan, Gang\|Jiang, Xian\|Han, Peng\|Zhai, Bo\|Dong, Xuesong\|Qiao, Haiquan\|Jiang, Hongchi\|Sun, Xueying
PMID:	27689326

263.
Journal:	Int J Oncol. 2016 Dec;49(6):2600-2610.
Title:	Knockdown of miR-25 increases the sensitivity of liver cancer stem cells to TRAIL-induced apoptosis via PTEN/PI3K/Akt/Bad signaling pathway.
Author:	Feng, Xiaoning\|Jiang, Jingjin\|Shi, Shaohua\|Xie, Haiyang\|Zhou, Lin\|Zheng, Shusen
PMID:	27840896

264.
Journal:	Cell Physiol Biochem. 2016;40(3-4):757-769.
Title:	PRSS8 is Downregulated and Suppresses Tumour Growth and Metastases in Hepatocellular Carcinoma.
Author:	Zhang, Li\|Jia, Guozhan\|Shi, Binya\|Ge, Guanqun\|Duan, Hongbin\|Yang, Yunsheng
PMID:	27915333

265.
Journal:	ACS Appl Mater Interfaces. 2016 Dec 14;8(49):33412-33422.
Title:	Gemcitabine and Antisense-microRNA Co-encapsulated PLGA-PEG Polymer Nanoparticles for Hepatocellular Carcinoma Therapy.
Author:	Devulapally, Rammohan\|Foygel, Kira\|Sekar, Thillai V\|Willmann, Juergen K\|Paulmurugan, Ramasamy
PMID:	27960411

266.
Journal:	Cell Rep. 2016 Dec 13;17(11):2979-2993.
Title:	Dual Shp2 and Pten Deficiencies Promote Non-alcoholic Steatohepatitis and Genesis of Liver Tumor-Initiating Cells.
Author:	Luo, Xiaolin\|Liao, Rui\|Hanley, Kaisa L\|Zhu, Helen He\|Malo, Kirsten N\|Hernandez, Carolyn\|Wei, Xufu\|Varki, Nissi M\|Alderson, Nazilla\|Chu, Catherine\|Li, Shuangwei\|Fan, Jia\|Loomba, Rohit\|Qiu, Shuang-Jian\|Feng, Gen-Sheng
PMID:	27974211

267.
Journal:	Clin Lab. 2016 Jul 1;62(7):1255-1264.
Title:	Expression and Prognostic Role of FHIT, Fibronectin, and PTEN in Hepatocellular Carcinoma.
Author:	Zhang, Ming-Jie\|Yan, Qiang\|Zhang, Guo-Lei\|Wie, Yun-Hai\|Yuan, Wen-Bin\|Xu, Wei\|Huang, Li-Feng
PMID:	28164627

268.
Journal:	Biochim Biophys Acta Proteins Proteom. 2017 Apr;1865(4):434-443.
Title:	Proteomic study of hepatocellular carcinoma using a novel modified aptamer-based array (SOMAscan) platform.
Author:	Qiao, Zhiwei\|Pan, Xiaoqing\|Parlayan, Cuneyd\|Ojima, Hidenori\|Kondo, Tadashi
PMID:	27663888

269.
Journal:	Cancer Lett. 2017 Mar 1;388:177-186.
Title:	STC2 as a novel mediator for Mus81-dependent proliferation and survival in hepatocellular carcinoma.
Author:	Wu, Fan\|Li, Ting-Yue\|Su, Shu-Chao\|Yu, Ji-Shang\|Zhang, Hao-Lu\|Tan, Guo-Qian\|Liu, Jian-Wei\|Wang, Bai-Lin
PMID:	27939696

270.
Journal:	Carcinogenesis. 2017 Feb 1;38(2):207-217.
Title:	Downregulation of AZGP1 by Ikaros and histone deacetylase promotes tumor progression through the PTEN/Akt and CD44s pathways in hepatocellular carcinoma.
Author:	Tian, Hua\|Ge, Chao\|Zhao, Fangyu\|Zhu, Miaoxin\|Zhang, Lin\|Huo, Qi\|Li, Hong\|Chen, Taoyang\|Xie, Haiyang\|Cui, Ying\|Yao, Ming\|Li, Jinjun
PMID:	27993894

271.
Journal:	Sci Rep. 2017 Jan 5;7:40089.
Title:	HBx promotes cell proliferation by disturbing the cross-talk between miR-181a and PTEN.
Author:	Tian, Yi\|Xiao, Xinqiang\|Gong, Xing\|Peng, Feng\|Xu, Yun\|Jiang, Yongfang\|Gong, Guozhong
PMID:	28053323

272.
Journal:	Toxicol In Vitro. 2017 Apr;40:115-123.
Title:	Alterations in transcription and protein expressions of HCC-related genes in HepG2 cells caused by microcystin-LR.
Author:	Li, Xiaoyu\|Zhang, Xiangyang\|Xie, Wenjie\|Zhou, Chune\|Li, Yao\|Zhang, Xiuhua
PMID:	28062358

273.
Journal:	World J Hepatol. 2017 Jan 8;9(1):18-29.
Title:	PI3K/SHIP2/PTEN pathway in cell polarity and hepatitis C virus pathogenesis.
Author:	Awad, Aline\|Gassama-Diagne, Ama
PMID:	28105255

274.
Journal:	PLoS One. 2017 Jan 23;12(1):e0170573.
Title:	TFDP3 Regulates Epithelial-Mesenchymal Transition in Breast Cancer.
Author:	Yin, Kailin\|Liu, Yanchen\|Chu, Ming\|Wang, Yuedan
PMID:	28114432

275.
Journal:	Cancer Sci. 2017 Apr;108(4):620-631.
Title:	MicroRNA-155-5p promotes hepatocellular carcinoma progression by suppressing PTEN through the PI3K/Akt pathway.
Author:	Fu, Xiao\|Wen, Hongqing\|Jing, Li\|Yang, Yujuan\|Wang, Wenjuan\|Liang, Xuan\|Nan, Kejun\|Yao, Yu\|Tian, Tao
PMID:	28132399

276.
Journal:	J Drug Target. 2017 Jul;25(6):513-522.
Title:	PTEN and TRAIL genes loaded zein nanoparticles as potential therapy for hepatocellular carcinoma.
Author:	El Sharkawi, Fathia Zaki\|Ewais, Shaimaa Mohammed\|Fahmy, Rania Hassan\|Rashed, Laila Ahmed
PMID:	28140697

277.
Journal:	Prostate. 2017 May;77(7):776-793.
Title:	The Effect of a Histone Deacetylase Inhibitor (AR-42) on Canine Prostate Cancer Growth and Metastasis.
Author:	Elshafae, Said M\|Kohart, Nicole A\|Altstadt, Lucas A\|Dirksen, Wessel P\|Rosol, Thomas J
PMID:	28181686

278.
Journal:	Oncotarget. 2017 Mar 14;8(11):18129-18144.
Title:	OIP5, a target of miR-15b-5p, regulates hepatocellular carcinoma growth and metastasis through the AKT/mTORC1 and beta-catenin signaling pathways.
Author:	Li, Hua\|Zhang, Jun\|Lee, Mi-Jin\|Yu, Goung-Ran\|Han, Xueji\|Kim, Dae-Ghon
PMID:	28184024

279.
Journal:	Int J Cancer. 2017 May 15;140(10):2284-2297.
Title:	Characterization of the GNMT-HectH9-PREX2 tripartite relationship in the pathogenesis of hepatocellular carcinoma.
Author:	Li, Chung-Hsien\|Yen, Chia-Hung\|Chen, Yen-Fu\|Lee, Kuo-Jui\|Fang, Cheng-Chieh\|Zhang, Xian\|Lai, Chih-Chung\|Huang, Shiu-Feng\|Lin, Hui-Kuan\|Arthur Chen, Yi-Ming
PMID:	28205209

280.
Journal:	Gastroenterology. 2017 Oct;153(4):1120-1132.e15.
Title:	MAN2A1-FER Fusion Gene Is Expressed by Human Liver and Other Tumor Types and Has Oncogenic Activity in Mice.
Author:	Chen, Zhang-Hui\|Yu, Yan P\|Tao, Junyan\|Liu, Silvia\|Tseng, George\|Nalesnik, Michael\|Hamilton, Ronald\|Bhargava, Rohit\|Nelson, Joel B\|Pennathur, Arjun\|Monga, Satdarshan P\|Luketich, James D\|Michalopoulos, George K\|Luo, Jian-Hua
PMID:	28245430

281.
Journal:	Redox Biol. 2017 Aug;12:340-349.
Title:	Butyrate induces ROS-mediated apoptosis by modulating miR-22/SIRT-1 pathway in hepatic cancer cells.
Author:	Pant, Kishor\|Yadav, Ajay K\|Gupta, Parul\|Islam, Rakibul\|Saraya, Anoop\|Venugopal, Senthil K
PMID:	28288414

282.
Journal:	Int J Oncol. 2017 May;50(5):1749-1759.
Title:	Transglutaminase 2 is upregulated in primary hepatocellular carcinoma with early recurrence as determined by proteomic profiles.
Author:	Yamaguchi, Hiromi\|Kuroda, Kazumichi\|Sugitani, Masahiko\|Takayama, Tadatoshi\|Hasegawa, Kiyoshi\|Esumi, Mariko
PMID:	28339069

283.
Journal:	Mol Med Rep. 2017 May;15(5):3285-3291.
Title:	Hepatitis B virus X protein increases microRNA21 expression and accelerates the development of hepatoma via the phosphatase and tensin homolog/phosphoinositide 3kinase/protein kinase B signaling pathway.
Author:	Hou, Zhouhua\|Quan, Jun
PMID:	28339072

284.
Journal:	Oncol Rep. 2017 Apr;37(4):2215-2226.
Title:	TP53 and RET may serve as biomarkers of prognostic evaluation and targeted therapy in hepatocellular carcinoma.
Author:	Ye, Song\|Zhao, Xin-Yi\|Hu, Xiao-Ge\|Li, Tang\|Xu, Qiu-Ran\|Yang, Huan-Ming\|Huang, Dong-Sheng\|Yang, Liu
PMID:	28350084

285.
Journal:	BMC Cancer. 2017 Apr 7;17(1):248.
Title:	Long non-coding RNA XIST regulates PTEN expression by sponging miR-181a and promotes hepatocellular carcinoma progression.
Author:	Chang, Shuzhen\|Chen, Binhe\|Wang, Xiaoyan\|Wu, Keqin\|Sun, Yuqiu
PMID:	28388883

286.
Journal:	Hum Pathol. 2017 Jun;64:69-75.
Title:	Coexpression of SALL4 with HDAC1 and/or HDAC2 is associated with underexpression of PTEN and poor prognosis in patients with hepatocellular carcinoma.
Author:	Wang, Huanlin\|Kohashi, Kenichi\|Yoshizumi, Tomoharu\|Okumura, Yukihiko\|Tanaka, Yuki\|Shimokawa, Masahiro\|Iwasaki, Takeshi\|Aishima, Shinichi\|Maehara, Yoshihiko\|Oda, Yoshinao
PMID:	28411180

287.
Journal:	Oncotarget. 2017 May 9;8(19):31745-31757.
Title:	MiR-425-5p promotes invasion and metastasis of hepatocellular carcinoma cells through SCAI-mediated dysregulation of multiple signaling pathways.
Author:	Fang, Feng\|Song, Tianqiang\|Zhang, Ti\|Cui, Yunlong\|Zhang, Gewen\|Xiong, Qingqing
PMID:	28423650

288.
Journal:	Cancer Cell Int. 2017 Apr 24;17:48.
Title:	Metformin exhibits the anti-proliferation and anti-invasion effects in hepatocellular carcinoma cells after insufficient radiofrequency ablation.
Author:	Zhang, Qingyun\|Kong, Jian\|Dong, Shuying\|Xu, Wenlei\|Sun, Wenbing
PMID:	28450808

289.
Journal:	Cell Physiol Biochem. 2017;41(6):2289-2306.
Title:	Alpha1-ACT Functions as a Tumour Suppressor in Hepatocellular Carcinoma by Inhibiting the PI3K/AKT/mTOR Signalling Pathway via Activation of PTEN.
Author:	Zhu, Hanzhang\|Liu, Qiaoyu\|Tang, Junwei\|Xie, Yu\|Xu, Xiaoliang\|Huang, Ruyi\|Zhang, Yuanguangyan\|Jin, Kangpeng\|Sun, Beicheng
PMID:	28456796

290.
Journal:	J Cell Biochem. 2017 Dec;118(12):4498-4507.
Title:	Long Noncoding RNA lncARSR Promotes Doxorubicin Resistance in Hepatocellular Carcinoma via Modulating PTEN-PI3K/Akt Pathway.
Author:	Li, Yaling\|Ye, Yun\|Feng, Bimin\|Qi, Yan
PMID:	28464252

291.
Journal:	Breast Cancer. 2017 Jul;24(4):521-527.
Title:	The role of miR-130a in cancer.
Author:	Zhang, He-da\|Jiang, Lin-Hong\|Sun, Da-Wei\|Li, Jian\|Ji, Zhen-Ling
PMID:	28477068

292.
Journal:	Mol Med Rep. 2017 Jul;16(1):208-214.
Title:	Inhibitors of PARP-1 exert inhibitory effects on the biological characteristics of hepatocellular carcinoma cells in vitro.
Author:	Mao, Xiaorong\|Du, Senrong\|Yang, Zhongxia\|Zhang, Liting\|Peng, Xuebin\|Jiang, Ni\|Zhou, Haiyu
PMID:	28498459

293.
Journal:	Int J Oncol. 2017 Jun;50(6):2180-2190.
Title:	Antibody to human alpha-fetoprotein inhibits cell growth of human hepatocellular carcinoma cells by resuscitating the PTEN molecule: in vitro experiments.
Author:	Ohkawa, Kiyoshi\|Asakura, Tadashi\|Tsukada, Yutaka\|Matsuura, Tomokazu
PMID:	28498467

294.
Journal:	Oncogene. 2017 Sep 14;36(37):5274-5284.
Title:	Thyroid hormone protects hepatocytes from HBx-induced carcinogenesis by enhancing mitochondrial turnover.
Author:	Chi, H-C\|Chen, S-L\|Lin, S-L\|Tsai, C-Y\|Chuang, W-Y\|Lin, Y-H\|Huang, Y-H\|Tsai, M-M\|Yeh, C-T\|Lin, K-H
PMID:	28504722

295.
Journal:	Cancer Biol Ther. 2017 Jul 3;18(7):505-512.
Title:	CRISPR/Cas9-based Pten knock-out and Sleeping Beauty Transposon-mediated Nras knock-in induces hepatocellular carcinoma and hepatic lipid accumulation in mice.
Author:	Gao, Mingming\|Liu, Dexi
PMID:	28513320

296.
Journal:	J Control Release. 2017 Jul 28;258:130-145.
Title:	Aptamer-mediated gene therapy enhanced antitumor activity against human hepatocellular carcinoma in vitro and in vivo.
Author:	Xiao, Shuangli\|Liu, Zhongbing\|Deng, Ruolan\|Li, Chunhong\|Fu, Shaozhi\|Chen, Guilan\|Zhang, Xiaoqin\|Ke, Famin\|Ke, Siyun\|Yu, Xin\|Wang, Shurong\|Zhong, Zhirong
PMID:	28522194

297.
Journal:	Sci Rep. 2017 May 18;7(1):2070.
Title:	The Fragment HMGA2-sh-3p20 from HMGA2 mRNA 3'UTR Promotes the Growth of Hepatoma Cells by Upregulating HMGA2.
Author:	Wang, Yuan\|Chen, Fuquan\|Yang, Zhe\|Zhao, Man\|Zhang, Shuqin\|Gao, Yuen\|Feng, Jinyan\|Yang, Guang\|Zhang, Weiying\|Ye, Lihong\|Zhang, Xiaodong
PMID:	28522832

298.
Journal:	Clin Cancer Res. 2017 Sep 15;23(18):5537-5546.
Title:	Multifunctional Effects of a Small-Molecule STAT3 Inhibitor on NASH and Hepatocellular Carcinoma in Mice.
Author:	Jung, Kwang Hwa\|Yoo, Wonbeak\|Stevenson, Heather L\|Deshpande, Dipti\|Shen, Hong\|Gagea, Mihai\|Yoo, Suk-Young\|Wang, Jing\|Eckols, T Kris\|Bharadwaj, Uddalak\|Tweardy, David J\|Beretta, Laura
PMID:	28533225

299.
Journal:	Sci Rep. 2017 Jun 5;7(1):2796.
Title:	CRISPR/Cas9-mediated p53 and Pten dual mutation accelerates hepatocarcinogenesis in adult hepatitis B virus transgenic mice.
Author:	Liu, Yongzhen\|Qi, Xuewei\|Zeng, Zhenzhen\|Wang, Lu\|Wang, Jie\|Zhang, Ting\|Xu, Qiang\|Shen, Congle\|Zhou, Guangde\|Yang, Shaomin\|Chen, Xiangmei\|Lu, Fengmin
PMID:	28584302

300.
Journal:	Tumour Biol. 2017 Jun;39(6):1010428317705754.
Title:	PTEN: A potential prognostic marker in virus-induced hepatocellular carcinoma.
Author:	Khalid, Ayesha\|Hussain, Tabinda\|Manzoor, Sobia\|Saalim, Muhammad\|Khaliq, Saba
PMID:	28621226

301.
Journal:	Sci Rep. 2017 Jun 16;7(1):3695.
Title:	The role of PTEN - HCV core interaction in hepatitis C virus replication.
Author:	Wu, Qi\|Li, Zhubing\|Mellor, Paul\|Zhou, Yan\|Anderson, Deborah H\|Liu, Qiang
PMID:	28623358

302.
Journal:	Oncogene. 2017 Oct 26;36(43):6020-6029.
Title:	Wnt/beta-catenin activation and macrophage induction during liver cancer development following steatosis.
Author:	Debebe, A\|Medina, V\|Chen, C-Y\|Mahajan, I M\|Jia, C\|Fu, D\|He, L\|Zeng, N\|Stiles, B W\|Chen, C-L\|Wang, M\|Aggarwal, K-R\|Peng, Z\|Huang, J\|Chen, J\|Li, M\|Dong, T\|Atkins, S\|Borok, Z\|Yuan, W\|Machida, K\|Ju, C\|Kahn, M\|Johnson, D\|Stiles, B L
PMID:	28671671

303.
Journal:	Sci Rep. 2017 Jul 11;7(1):5134.
Title:	Hydrogen sulfide acts as a double-edged sword in human hepatocellular carcinoma cells through EGFR/ERK/MMP-2 and PTEN/AKT signaling pathways.
Author:	Wu, Dongdong\|Li, Mengling\|Tian, Wenke\|Wang, Shuaiwei\|Cui, Longzhen\|Li, Hui\|Wang, Huijuan\|Ji, Ailing\|Li, Yanzhang
PMID:	28698660

304.
Journal:	Eur J Cancer. 2017 Sep;83:56-70.
Title:	New liver cancer biomarkers: PI3K/AKT/mTOR pathway members and eukaryotic translation initiation factors.
Author:	Golob-Schwarzl, Nicole\|Krassnig, Stefanie\|Toeglhofer, Anna M\|Park, Young Nyun\|Gogg-Kamerer, Margit\|Vierlinger, Klemens\|Schroder, Fabian\|Rhee, Hyungjn\|Schicho, Rudolf\|Fickert, Peter\|Haybaeck, Johannes
PMID:	28715695

305.
Journal:	Oncol Rep. 2017 Sep;38(3):1845-1850.
Title:	Inhibitory effects of 1,25(OH)2D3 on the proliferation of hepatocellular carcinoma cells through the downregulation of HDAC2.
Author:	Huang, Jian\|Yang, Guozhen\|Huang, Yunzhu\|Zhang, Shu
PMID:	28737824

306.
Journal:	Evid Based Complement Alternat Med. 2017;2017:4063865.
Title:	Curcumin Induces p53-Null Hepatoma Cell Line Hep3B Apoptosis through the AKT-PTEN-FOXO4 Pathway.
Author:	Liou, An-Ting\|Chen, Mei-Fang\|Yang, Chu-Wen
PMID:	28769986

307.
Journal:	Virology. 2017 Nov;511:1-8.
Title:	Treatment with PTEN-Long protein inhibits hepatitis C virus replication.
Author:	Wu, Qi\|Li, Zhubing\|Liu, Qiang
PMID:	28783500

308.
Journal:	Toxicol In Vitro. 2017 Dec;45(Pt 1):44-53.
Title:	ONTD induces growth arrest and apoptosis of human hepatoma Bel-7402 cells though a peroxisome proliferator-activated receptor gamma-dependent pathway.
Author:	Tan, Jiani\|Shen, Weixing\|Shi, Wenjing\|Chen, Xi\|Sun, Dongdong\|Xu, Changliang\|Yan, Qiuying\|Cheng, Haibo\|Lai, Yisheng\|Ji, Hui
PMID:	28834734

309.
Journal:	Biomed Pharmacother. 2017 Nov;95:324-330.
Title:	Effect and Mechanism of Sophoridine to suppress Hepatocellular carcinoma in vitro and vivo.
Author:	Wang, BaoChun\|Xu, Jian\|Wang, HaiYang\|Chang, ShunWu\|Liu, Ning
PMID:	28858730

310.
Journal:	Theranostics. 2017 Jul 22;7(13):3228-3242.
Title:	Combination of AAV-TRAIL with miR-221-Zip Therapeutic Strategy Overcomes the Resistance to TRAIL Induced Apoptosis in Liver Cancer.
Author:	Ma, Sisi\|Sun, Jiazeng\|Guo, Yabin\|Zhang, Peng\|Liu, Yanxin\|Zheng, Dexian\|Shi, Juan
PMID:	28900506

311.
Journal:	Int J Biochem Cell Biol. 2017 Nov;92:34-42.
Title:	Long non-coding RNA 657 suppresses hepatocellular carcinoma cell growth by acting as a molecular sponge of miR-106a-5p to regulate PTEN expression.
Author:	Hu, Bingren\|Cai, Huajie\|Zheng, Ru\|Yang, Shouzhang\|Zhou, Zhenxu\|Tu, Jinfu
PMID:	28919047

312.
Journal:	Oncol Lett. 2017 Sep;14(3):2649-2656.
Title:	NEDD4 promotes cell growth and migration via PTEN/PI3K/AKT signaling in hepatocellular carcinoma.
Author:	Huang, Zhi-Jun\|Zhu, Jun-Jun\|Yang, Xiao-Yu\|Biskup, Ewelina
PMID:	28928809

313.
Journal:	Oncol Lett. 2017 Oct;14(4):4767-4771.
Title:	Ligands of the peroxisome proliferator-activated receptor gamma inhibit hepatoce llular carcinoma cell proliferation.
Author:	Jin, Zhe\|Jia, Baoxing\|Fu, Yu\|Tan, Ludong\|Chen, Qingmin\|Jiang, Peiqiang\|Liu, Yahui
PMID:	28943966

314.
Journal:	J BUON. 2017 Jul-Aug;22(4):942-946.
Title:	Correlation between expression levels of PTEN and p53 genes and the clinical features of HBsAg-positive liver cancer.
Author:	Chai, Yang\|Xiaoyu, Liu\|Haiyan, Wang
PMID:	28952211

315.
Journal:	Am J Transl Res. 2017 Sep 15;9(9):4300-4307. eCollection 2017.
Title:	MicroRNA-205-5p regulates the chemotherapeutic resistance of hepatocellular carcinoma cells by targeting PTEN/JNK/ANXA3 pathway.
Author:	Shao, Ping\|Qu, Wei-Kun\|Wang, Cheng-Ye\|Tian, Yu\|Ye, Ming-Liang\|Sun, De-Guang\|Sui, Ji-Dong\|Wang, Li-Ming\|Fan, Rong\|Gao, Zhen-Ming
PMID:	28979703

316.
Journal:	Int J Oncol. 2017 Nov;51(5):1449-1459.
Title:	Regulation of ERK and AKT pathways by hepatitis B virus X protein via the Notch1 pathway in hepatocellular carcinoma.
Author:	Liao, Bo\|Zhou, Honghao\|Liang, Huifang\|Li, Changhai
PMID:	29048612

317.
Journal:	Sci Rep. 2017 Nov 1;7(1):14841.
Title:	Spermine oxidase promotes bile canalicular lumen formation through acrolein production.
Author:	Uemura, Takeshi\|Takasaka, Tomokazu\|Igarashi, Kazuei\|Ikegaya, Hiroshi
PMID:	29093526

318.
Journal:	Hepatol Commun. 2017 Apr;1(2):153-167.
Title:	Crosstalk of LKB1- and PTEN-regulated signals in liver morphogenesis and tumor development.
Author:	Jia, Chengyou\|Medina, Vivian\|Liu, Chenchang\|He, Lina\|Qian, Daohai\|Taojian, Tu\|Okamoto, Curtis T\|Stiles, Bangyan L
PMID:	29152604

319.
Journal:	Cell Physiol Biochem. 2017;44(3):1188-1198.
Title:	Long Non-Coding RNA Linc-USP16 Functions As a Tumour Suppressor in Hepatocellular Carcinoma by Regulating PTEN Expression.
Author:	Sui, Jidong\|Yang, Xuejun\|Qi, Wenjing\|Guo, Kun\|Gao, Zhenming\|Wang, Liming\|Sun, Deguang
PMID:	29179215

320.
Journal:	Oncotarget. 2017 Aug 1;8(51):88517-88528.
Title:	MicroRNA deregulation in nonalcoholic steatohepatitis-associated liver carcinogenesis.
Author:	de Conti, Aline\|Ortega, Juliana Festa\|Tryndyak, Volodymyr\|Dreval, Kostiantyn\|Moreno, Fernando Salvador\|Rusyn, Ivan\|Beland, Frederick A\|Pogribny, Igor P
PMID:	29179453

321.
Journal:	Oncotarget. 2017 Nov 6;8(64):107859-107869.
Title:	Long non-coding RNA PTENP1 interacts with miR-193a-3p to suppress cell migration and invasion through the PTEN pathway in hepatocellular carcinoma.
Author:	Qian, Yu-Yuan\|Li, Kun\|Liu, Quan-Yan\|Liu, Zhi-Su
PMID:	29296207

322.
Journal:	Anticancer Agents Med Chem. 2017 Dec 29. pii: ACAMC-EPUB-87644.
Title:	Fisetin Attenuates AKT Associated Growth Promoting Events in AflatoxinB1 Induced Hepatocellular Carcinoma.
Author:	Maurya, Brajesh Kumar\|Trigun, Surendra Kumar
PMID:	29298655

323.
Journal:	Oncotarget. 2017 Nov 30;8(66):110576-110591.
Title:	C21 steroid-enriched fraction refined from Marsdenia tenacissima inhibits hepatocellular carcinoma through the coordination of Hippo-Yap and PTEN-PI3K/AKT signaling pathways.
Author:	Zhang, Yu\|Li, Kaiqiang\|Ying, Youmin\|Chen, Bingyu\|Hao, Ke\|Chen, Boxu\|Zheng, Yu\|Lyu, Jianxin\|Tong, Xiangming\|Chen, Xiaopan\|Wang, Ying\|Zhan, Zhajun\|Zhang, Wei\|Wang, Zhen
PMID:	29299170

324.
Journal:	Am J Transl Res. 2017 Dec 15;9(12):5567-5575. eCollection 2017.
Title:	Curcumin combined with glycyrrhetinic acid inhibits the development of hepatocellular carcinoma cells by down-regulating the PTEN/PI3K/AKT signalling pathway.
Author:	Chang, Mingxiang\|Wu, Meimei\|Li, Hanmin
PMID:	29312508

325.
Journal:	Rom J Morphol Embryol. 2017;58(4):1257-1262.
Title:	The tyrosine kinase inhibitors effects on metastatic tumor graft in the chick chorioallantoic membrane assay.
Author:	Ciolofan, Alexandru\|Cretu, Octavian Marius\|Mogoanta, Stelian Stefanita\|Ciuca, Eduard Mihai
PMID:	29556614

326.
Journal:	Folia Biol (Praha). 2017;63(5-6):202-208.
Title:	Comparison of Subtypes of Hepatocellular Adenoma to Hepatocellular Carcinoma and Non-Neoplastic Liver Tissue in Terms of PTEN Expression.
Author:	Szparecki, G\|Ilczuk, T\|Gabzdyl, N\|Gornicka, B
PMID:	29687774

327.
Journal:	Mol Carcinog. 2018 Jan;57(1):44-56.
Title:	Metformin incombination with curcumin inhibits the growth, metastasis, and angiogenesis of hepatocellular carcinoma in vitro and in vivo.
Author:	Zhang, Hui-Hui\|Zhang, Ying\|Cheng, Yan-Na\|Gong, Fu-Lian\|Cao, Zhan-Qi\|Yu, Lu-Gang\|Guo, Xiu-Li
PMID:	28833603

328.
Journal:	Hepatology. 2018 May;67(5):1842-1856.
Title:	Cytoplasmic localization of the cell polarity factor scribble supports liver tumor formation and tumor cell invasiveness.
Author:	Wan, Shan\|Meyer, Anne-Sophie\|Weiler, Sofia Maria Elisabeth\|Rupp, Christian\|Toth, Marcell\|Sticht, Carsten\|Singer, Stephan\|Thomann, Stefan\|Roessler, Stephanie\|Schorpp-Kistner, Marina\|Schmitt, Jennifer\|Gretz, Norbert\|Angel, Peter\|Tschaharganeh, Darjus Felix\|
PMID:	29152770

329.
Journal:	Biomed Pharmacother. 2018 Jan;97:1282-1288.
Title:	Synergistic anticancer activity of 20(S)-Ginsenoside Rg3 and Sorafenib in hepatocellular carcinoma by modulating PTEN/Akt signaling pathway.
Author:	Lu, Mingxia\|Fei, Zhenghua\|Zhang, Ganlu
PMID:	29156516

330.
Journal:	Hepatology. 2018 May;67(5):1857-1871.
Title:	C/EBPalpha-dependent preneoplastic tumor foci are the origin of hepatocellular carcinoma and aggressive pediatric liver cancer.
Author:	Cast, Ashley\|Valanejad, Leila\|Wright, Mary\|Nguyen, Phuong\|Gupta, Anita\|Zhu, Liqin\|Shin, Soona\|Timchenko, Nikolai
PMID:	29159818

331.
Journal:	IUBMB Life. 2018 Feb;70(2):120-128.
Title:	Downregulation of STRAP promotes tumor growth and metastasis in hepatocellular carcinoma via reducing PTEN level.
Author:	Wu, Qiong\|Yu, Shijun\|Chen, Jingde\|Li, Yandong\|Gao, Yong
PMID:	29283497

332.
Journal:	Exp Mol Med. 2018 Jan 5;50(1):e417.
Title:	Loss of Pten synergizes with c-Met to promote hepatocellular carcinoma development via mTORC2 pathway.
Author:	Xu, Zhong\|Hu, Junjie\|Cao, Hui\|Pilo, Maria G\|Cigliano, Antonio\|Shao, Zixuan\|Xu, Meng\|Ribback, Silvia\|Dombrowski, Frank\|Calvisi, Diego F\|Chen, Xin
PMID:	29303510

333.
Journal:	Exp Mol Med. 2018 Jan 5;50(1):e422.
Title:	Depletion of S100A4(+) stromal cells does not prevent HCC development but reduces the stem cell-like phenotype of the tumors.
Author:	Jiao, Jingjing\|Gonzalez, Alvaro\|Stevenson, Heather L\|Gagea, Mihai\|Sugimoto, Hikaru\|Kalluri, Raghu\|Beretta, Laura
PMID:	29303514

334.
Journal:	Cell Death Dis. 2018 Jan 5;9(1):4.
Title:	The epigenetically regulated miR-494 associates with stem-cell phenotype and induces sorafenib resistance in hepatocellular carcinoma.
Author:	Pollutri, Daniela\|Patrizi, Clarissa\|Marinelli, Sara\|Giovannini, Catia\|Trombetta, Elena\|Giannone, Ferdinando A\|Baldassarre, Maurizio\|Quarta, Santina\|Vandewynckel, Y P\|Vandierendonck, A\|Van Vlierberghe, H\|Porretti, Laura\|Negrini, Massimo\|Bolondi, Luigi\|Gram
PMID:	29305580

335.
Journal:	PLoS One. 2018 Jan 31;13(1):e0191805.
Title:	Simvastatin and metformin inhibit cell growth in hepatitis C virus infected cells via mTOR increasing PTEN and autophagy.
Author:	Del Campo, Jose A\|Garcia-Valdecasas, Marta\|Gil-Gomez, Antonio\|Rojas, Angela\|Gallego, Paloma\|Ampuero, Javier\|Gallego-Duran, Rocio\|Pastor, Helena\|Grande, Lourdes\|Padillo, Francisco J\|Muntane, Jordi\|Romero-Gomez, Manuel
PMID:	29385181

336.
Journal:	Acta Pharmacol Sin. 2018 Feb;39(2):329.
Title:	Erratum: Argonaute 2 promotes angiogenesis via the PTEN/VEGF signaling pathway in human hepatocellular carcinoma.
Author:
PMID:	29388571

337.
Journal:	Mol Med Rep. 2018 Apr;17(4):5193-5201.
Title:	Pterostilbene increases PTEN expression through the targeted downregulation of microRNA-19a in hepatocellular carcinoma.
Author:	Qian, Yu-Yuan\|Liu, Zhi-Su\|Zhang, Zidong\|Levenson, Anait S\|Li, Kun
PMID:	29393488

338.
Journal:	J Clin Invest. 2018 Mar 1;128(3):1010-1025.
Title:	Hippo-mediated suppression of IRS2/AKT signaling prevents hepatic steatosis and liver cancer.
Author:	Jeong, Sun-Hye\|Kim, Han-Byul\|Kim, Min-Chul\|Lee, Ji-Min\|Lee, Jae Ho\|Kim, Jeong-Hwan\|Kim, Jin-Woo\|Park, Woong-Yang\|Kim, Seon-Young\|Kim, Jae Bum\|Kim, Haeryoung\|Kim, Jin-Man\|Choi, Hueng-Sik\|Lim, Dae-Sik
PMID:	29400692

339.
Journal:	Onco Targets Ther. 2018 Jan 26;11:571-585.
Title:	miR-106b-5p promotes stem cell-like properties of hepatocellular carcinoma cells by targeting PTEN via PI3K/Akt pathway.
Author:	Shi, Dong-Min\|Bian, Xin-Yu\|Qin, Cheng-Dong\|Wu, Wei-Zhong
PMID:	29416358

340.
Journal:	Cell Death Dis. 2018 Feb 15;9(3):253.
Title:	Long noncoding RNA MEG3 suppresses liver cancer cells growth through inhibiting beta-catenin by activating PKM2 and inactivating PTEN.
Author:	Zheng, Qidi\|Lin, Zhuojia\|Xu, Jie\|Lu, Yanan\|Meng, Qiuyu\|Wang, Chen\|Yang, Yuxin\|Xin, Xiaoru\|Li, Xiaonan\|Pu, Hu\|Gui, Xin\|Li, Tianming\|Xiong, Wujun\|Lu, Dongdong
PMID:	29449541

341.
Journal:	Cancer Lett. 2018 May 1;421:161-169.
Title:	Combination of Kras activation and PTEN deletion contributes to murine hepatopancreatic ductal malignancy.
Author:	Lin, Yun-Kai\|Fang, Zheng\|Jiang, Tian-Yi\|Wan, Zheng-Hua\|Pan, Yu-Fei\|Ma, Yun-Han\|Shi, Yuan-Yuan\|Tan, Ye-Xiong\|Dong, Li-Wei\|Zhang, Yong-Jie\|Wang, Hong-Yang
PMID:	29452147

342.
Journal:	Oncotarget. 2017 Dec 21;9(6):6830-6840.
Title:	Characterization of aptamer-mediated gene delivery system for liver cancer therapy.
Author:	Liu, Zhongbing\|Sun, Xiaoduan\|Xiao, Shuangli\|Lin, Yan\|Li, Chunhong\|Hao, Na\|Zhou, Meiling\|Deng, Ruolan\|Ke, Siyun\|Zhong, Zhirong
PMID:	29467932

343.
Journal:	Int J Mol Med. 2018 May;41(5):2813-2831.
Title:	Downregulated miR-23b-3p expression acts as a predictor of hepatocellular carcinoma progression: A study based on public data and RT-qPCR verification.
Author:	He, Rong-Quan\|Wu, Pei-Rong\|Xiang, Xue-Lian\|Yang, Xia\|Liang, Hai-Wei\|Qiu, Xiao-Hui\|Yang, Li-Hua\|Peng, Zhi-Gang\|Chen, Gang
PMID:	29484429

344.
Journal:	Pathol Res Pract. 2018 Mar;214(3):436-441.
Title:	High-expressed CKS2 is associated with hepatocellular carcinoma cell proliferation through down-regulating PTEN.
Author:	Ji, Xiaonan\|Xue, Yayu\|Wu, Yu\|Feng, Fang\|Gao, Xiangdong
PMID:	29487004

345.
Journal:	Oncologist. 2018 May;23(5):586-593.
Title:	Next-Generation Sequencing of Circulating Tumor DNA Reveals Frequent Alterations in Advanced Hepatocellular Carcinoma.
Author:	Ikeda, Sadakatsu\|Tsigelny, Igor F\|Skjevik, Age A\|Kono, Yuko\|Mendler, Michel\|Kuo, Alexander\|Sicklick, Jason K\|Heestand, Gregory\|Banks, Kimberly C\|Talasaz, AmirAli\|Lanman, Richard B\|Lippman, Scott\|Kurzrock, Razelle
PMID:	29487225

346.
Journal:	Onco Targets Ther. 2018 Feb 26;11:983-996.
Title:	Kanglaite reverses multidrug resistance of HCC by inducing apoptosis and cell cycle arrest via PI3K/AKT pathway.
Author:	Yang, Chendong\|Hou, Aihua\|Yu, Chunfeng\|Dai, Lingling\|Wang, Wen\|Zhang, Kangle\|Shao, Hongmin\|Ma, Jinghua\|Xu, Wenjuan
PMID:	29520149

347.
Journal:	J Exp Clin Cancer Res. 2018 Mar 9;37(1):51.
Title:	C-Myc-dependent repression of two oncogenic miRNA clusters contributes to triptolide-induced cell death in hepatocellular carcinoma cells.
Author:	Li, Shu-Guang\|Shi, Qian-Wei\|Yuan, Ling-Yan\|Qin, Li-Ping\|Wang, Yan\|Miao, Yu-Qing\|Chen, Zhe\|Ling, Chang-Quan\|Qin, Wen-Xing
PMID:	29523159

348.
Journal:	J Exp Clin Cancer Res. 2018 Mar 12;37(1):52.
Title:	Exosomal microRNA-32-5p induces multidrug resistance in hepatocellular carcinoma via the PI3K/Akt pathway.
Author:	Fu, Xiao\|Liu, Mengjie\|Qu, Shengyang\|Ma, Jiequn\|Zhang, Yamin\|Shi, Tingting\|Wen, Hongqing\|Yang, Yujuan\|Wang, Shuhong\|Wang, Jing\|Nan, Kejun\|Yao, Yu\|Tian, Tao
PMID:	29530052

349.
Journal:	Cell Commun Signal. 2018 Mar 12;16(1):9.
Title:	Inhibition of CREB binding protein-beta-catenin signaling down regulates CD133 expression and activates PP2A-PTEN signaling in tumor initiating liver cancer cells.
Author:	Tang, Yuanyuan\|Berlind, Joshua\|Mavila, Nirmala
PMID:	29530069

350.
Journal:	Br J Pharmacol. 2018 Jun;175(12):2441-2453.
Title:	Resolvin D1 attenuates liver ischaemia/reperfusion injury through modulating thioredoxin 2-mediated mitochondrial quality control.
Author:	Kang, Jung-Woo\|Choi, Hyo-Sun\|Lee, Sun-Mee
PMID:	29569721

351.
Journal:	Biomed Pharmacother. 2018 May;101:852-859.
Title:	Pterostilbene inhibits MTA1/HDAC1 complex leading to PTEN acetylation in hepatocellular carcinoma.
Author:	Qian, Yu-Yuan\|Liu, Zhi-Su\|Yan, Hua-Jun\|Yuan, Yu-Feng\|Levenson, Anait S\|Li, Kun
PMID:	29635894

352.
Journal:	Evid Based Complement Alternat Med. 2018 Feb 15;2018:3021476.
Title:	Total Flavonoids from Oroxylum indicum Induce Apoptosis via PI3K/Akt/PTEN Signaling Pathway in Liver Cancer.
Author:	Li, Nan-Nan\|Meng, Xian-Sheng\|Men, Wen-Xiao\|Bao, Yong-Rui\|Wang, Shuai
PMID:	29636773

353.
Journal:	Sci Transl Med. 2018 Apr 18;10(437). pii: 10/437/eaap9840.
Title:	Squalene epoxidase drives NAFLD-induced hepatocellular carcinoma and is a pharmaceutical target.
Author:	Liu, Dabin\|Wong, Chi Chun\|Fu, Li\|Chen, Huarong\|Zhao, Liuyang\|Li, Chuangen\|Zhou, Yunfei\|Zhang, Yanquan\|Xu, Weiqi\|Yang, Yidong\|Wu, Bin\|Cheng, Gong\|Lai, Paul Bo-San\|Wong, Nathalie\|Sung, Joseph J Y\|Yu, Jun
PMID:	29669855

354.
Journal:	Biomed Pharmacother. 2018 Jul;103:746-754.
Title:	Naringenin improve hepatitis C virus infection induced insulin resistance by increase PTEN expression via p53-dependent manner.
Author:	Jia, Benli\|Yu, Dongsheng\|Yu, Gang\|Cheng, Yunsheng\|Wang, Yang\|Yi, Xiaoqiang\|Li, Xiaoping\|Wang, Yong
PMID:	29684853

355.
Journal:	BMB Rep. 2018 May;51(5):209-210.
Title:	Insulin receptor substrate 2: a bridge between Hippo and AKT pathways.
Author:	Jeong, Sun-Hye\|Lim, Dae-Sik
PMID:	29699606

356.
Journal:	Biochem Cell Biol. 2018 Apr 30.
Title:	The phosphoinositide 3-kinase (PI3K) pathway and glycogen synthase kinase-3 (GSK-3) positively regulate the activity of metal-responsive transcription factor-1 (MTF-1) in response to zinc ions.
Author:	Andeol, Yannick\|Bonneau, Jessica\|M Gagne, Laurence\|Jacquet, Kevin\|Rivest, Veronique\|Huot, Marc-Etienne\|Seguin, Carl
PMID:	29707960

357.
Journal:	Br J Cancer. 2018 May;118(10):1337-1348.
Title:	Chemerin suppresses hepatocellular carcinoma metastasis through CMKLR1-PTEN-Akt axis.
Author:	Li, Jing-Jing\|Yin, Hong-Kun\|Guan, Dong-Xian\|Zhao, Jiang-Sha\|Feng, Yu-Xiong\|Deng, Yue-Zhen\|Wang, Xiang\|Li, Nan\|Wang, Xiao-Fan\|Cheng, Shu-Qun\|Bao, Ying\|Xie, Dong
PMID:	29717200

358.
Journal:	Pharmacogn Mag. 2018 Apr-Jun;14(54):207-213.
Title:	Evidence for the Involvement of COX-2/VEGF and PTEN/Pl3K/AKT Pathway the Mechanism of Oroxin B Treated Liver Cancer.
Author:	Li, Nan-Nan\|Meng, Xian-Sheng\|Bao, Yong-Rui\|Wang, Shuai\|Li, Tian-Jiao
PMID:	29720833

359.
Journal:	Virology. 2018 Jul;520:94-102.
Title:	An important role of SREBP-1 in HBV and HCV co-replication inhibition by PTEN.
Author:	Wu, Qi\|Li, Zhubing\|Liu, Qiang
PMID:	29803738

360.
Journal:	Zhonghua Gan Zang Bing Za Zhi. 2018 Feb 20;26(2):142-144.
Title:	[Effect of Gleditsia sinesis extract on miRNA21 and PTEN gene in liver cancer rat].
Author:	Cai, Y\|Zhan, L\|Zhang, C Z\|Wang, X D\|Lu, D B\|Cheng, L B\|Xu, H L\|Wang, X S
PMID:	29804382

361.
Journal:	Med Sci Monit. 2018 May 29;24:3571-3577.
Title:	Suppression of miR-21 Expression Inhibits Cell Proliferation and Migration of Liver Cancer Cells by Targeting Phosphatase and Tensin Homolog (PTEN).
Author:	Liu, Haiwei\|Cheng, Le\|Cao, Dengke\|Zhang, Hu
PMID:	29807978

362.
Journal:	Mol Med Rep. 2018 Jul;18(1):911-919.
Title:	Matrine inhibits the invasive and migratory properties of human hepatocellular carcinoma by regulating epithelialmesenchymal transition.
Author:	Wang, Yuwen\|Zhang, Shujun\|Liu, Jia\|Fang, Biaobiao\|Yao, Jie\|Cheng, Binglin
PMID:	29845189

363.
Journal:	Mol Ther Nucleic Acids. 2018 Jun 1;11:494-507.
Title:	miR372 Promotes Progression of Liver Cancer Cells by Upregulating erbB-2 through Enhancement of YB-1.
Author:	Lin, Zhuojia\|Lu, Yanan\|Meng, Qiuyu\|Wang, Chen\|Li, Xiaonan\|Yang, Yuxin\|Xin, Xiaoru\|Zheng, Qidi\|Xu, Jie\|Gui, Xin\|Li, Tianming\|Pu, Hu\|Xiong, Wujun\|Li, Jiao\|Jia, Song\|Lu, Dongdong
PMID:	29858084

364.
Journal:	Mol Cancer. 2018 Jun 12;17(1):94.
Title:	Long noncoding RNA HULC accelerates liver cancer by inhibiting PTEN via autophagy cooperation to miR15a.
Author:	Xin, Xiaoru\|Wu, Mengying\|Meng, Qiuyu\|Wang, Chen\|Lu, Yanan\|Yang, Yuxin\|Li, Xiaonan\|Zheng, Qidi\|Pu, Hu\|Gui, Xin\|Li, Tianming\|Li, Jiao\|Jia, Song\|Lu, Dongdong
PMID:	29895332

365.
Journal:	Adv Exp Med Biol. 2018;1061:55-62.
Title:	NAFLD Related-HCC: The Relationship with Metabolic Disorders.
Author:	Zhang, Xiang
PMID:	29956206

366.
Journal:	Cell Signal. 2018 Oct;50:90-99.
Title:	HRD1-mediated PTEN degradation promotes cell proliferation and hepatocellular carcinoma progression.
Author:	Liu, Liu\|Long, Hua\|Wu, Yan\|Li, Hui\|Dong, Ling\|Zhong, Julia Li\|Liu, Zhaojian\|Yang, Xiaolong\|Dai, Xiaotian\|Shi, Lei\|Ren, Maozhi\|Lin, Zhenghong
PMID:	29958993

367.
Journal:	J Biochem Mol Toxicol. 2018 Aug;32(8):e22167.
Title:	MicroRNA-760 Inhibits Doxorubicin Resistance in Hepatocellular Carcinoma through Regulating Notch1/Hes1-PTEN/Akt Signaling Pathway.
Author:	Tian, Tao\|Fu, Xiao\|Lu, Jun\|Ruan, Zhiping\|Nan, Kejun\|Yao, Yu\|Yang, Yujuan
PMID:	29968951

368.
Journal:	Cancer Genomics Proteomics. 2018 Jul-Aug;15(4):291-298.
Title:	Comparing Clonality Between Components of Combined Hepatocellular Carcinoma and Cholangiocarcinoma by Targeted Sequencing.
Author:	Jeon, Jinyoung\|Maeng, Lee-So\|Bae, Yoon Jin\|Lee, Eui-Jin\|Yoon, Young Chul\|Yoon, Nara
PMID:	29976634

369.
Journal:	Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):E7119-E7128.
Title:	Targeting cancer addiction for SALL4 by shifting its transcriptome with a pharmacologic peptide.
Author:	Liu, Bee Hui\|Jobichen, Chacko\|Chia, C S Brian\|Chan, Tim Hon Man\|Tang, Jing Ping\|Chung, Theodora X Y\|Li, Jia\|Poulsen, Anders\|Hung, Alvin W\|Koh-Stenta, Xiaoying\|Tan, Yaw Sing\|Verma, Chandra S\|Tan, Hong Kee\|Wu, Chan-Shuo\|Li, Feng\|Hill, Jeffrey\|Joy, Joma\|Yang
PMID:	29976840

370.
Journal:	Sci Rep. 2018 Jul 11;8(1):10461.
Title:	MiR-494-3p promotes PI3K/AKT pathway hyperactivation and human hepatocellular carcinoma progression by targeting PTEN.
Author:	Lin, Hui\|Huang, Zhi-Ping\|Liu, Jiao\|Qiu, Yun\|Tao, Yuan-Ping\|Wang, Meng-Chao\|Yao, Hui\|Hou, Ke-Zhu\|Gu, Fang-Ming\|Xu, Xuan-Fu
PMID:	29992971

371.
Journal:	Cancer Lett. 2018 Oct 10;434:33-41.
Title:	Telomerase reverse transcriptase regulates DNMT3B expression/aberrant DNA methylation phenotype and AKT activation in hepatocellular carcinoma.
Author:	Yu, Jingya\|Yuan, Xiaotian\|Sjoholm, Louise\|Liu, Tiantian\|Kong, Feng\|Ekstrom, Tomas J\|Bjorkholm, Magnus\|Xu, Dawei
PMID:	30017965

372.
Journal:	Biomed Pharmacother. 2018 Sep;105:1147-1154.
Title:	microRNA-19a-3p promotes tumor metastasis and chemoresistance through the PTEN/Akt pathway in hepatocellular carcinoma.
Author:	Jiang, Xue-Mei\|Yu, Xiang-Nan\|Liu, Tao-Tao\|Zhu, Hai-Rong\|Shi, Xuan\|Bilegsaikhan, Enkhnaran\|Guo, Hong-Ying\|Song, Guang-Qi\|Weng, Shu-Qiang\|Huang, Xiao-Xi\|Dong, Ling\|Janssen, Harry L A\|Shen, Xi-Zhong\|Zhu, Ji-Min
PMID:	30021351

373.
Journal:	Oncotarget. 2018 Jun 29;9(50):29495-29507.
Title:	Toll-like receptor 4: a target for chemoprevention of hepatocellular carcinoma in obesity and steatohepatitis.
Author:	Nguyen, Jennifer\|Jiao, Jingjing\|Smoot, Kristin\|Watt, Gordon P\|Zhao, Chen\|Song, Xingzhi\|Stevenson, Heather L\|McCormick, Joseph B\|Fisher-Hoch, Susan P\|Zhang, Jianhua\|Futreal, P Andrew\|Beretta, Laura
PMID:	30034633

374.
Journal:	Cancer Lett. 2018 Nov 1;436:139-148.
Title:	USP10 suppresses tumor progression by inhibiting mTOR activation in hepatocellular carcinoma.
Author:	Lu, Chang\|Ning, Zhen\|Wang, Aman\|Chen, Di\|Liu, Xiaolong\|Xia, Tian\|Tekcham, Dinesh Singh\|Wang, Wen\|Li, Tongming\|Liu, Xiumei\|Liu, Jing\|Qi, Huan\|Luo, Haifeng\|Du, Jian\|Ma, Chi\|Yan, Qiu\|Liu, Jiwei\|Xu, Guowang\|Piao, Hai-Long\|Tan, Guang
PMID:	30056112

375.
Journal:	Yonsei Med J. 2018 Sep;59(7):816-826.
Title:	XIST Induced by JPX Suppresses Hepatocellular Carcinoma by Sponging miR-155-5p.
Author:	Lin, Xiu Qing\|Huang, Zhi Ming\|Chen, Xin\|Wu, Fang\|Wu, Wei
PMID:	30091314

376.
Journal:	Hepatol Commun. 2018 Jul 12;2(8):941-955.
Title:	A Survey of Molecular Heterogeneity in Hepatocellular Carcinoma.
Author:	Jovel, Juan\|Lin, Zhen\|O'keefe, Sandra\|Willows, Steven\|Wang, Weiwei\|Zhang, Guangzhi\|Patterson, Jordan\|Moctezuma-Velazquez, Carlos\|Kelvin, David J\|Ka-Shu Wong, Gane\|Mason, Andrew L
PMID:	30094405

377.
Journal:	Gene. 2018 Aug 7. pii: S0378-1119(18)30872-2.
Title:	BMI1 and PTEN are key determinants of breast cancer therapy: A plausible therapeutic target in breast cancer.
Author:	Janaki Ramaiah, M\|Vaishnave, S
PMID:	30096458

378.
Journal:	Gene. 2018 Aug 8. pii: S0378-1119(18)30898-9.
Title:	Long non-coding RNA THOR promotes cell proliferation and metastasis in hepatocellular carcinoma.
Author:	Cheng, Zhangjun\|Lei, Zhengqing\|Yang, Pinghua\|Si, Anfeng\|Xiang, Daimin\|Zhou, Jiahua\|Huser, Norbert
PMID:	30098425

379.
Journal:	Am J Pathol. 2018 Aug 27. pii: S0002-9440(18)30136-6.
Title:	Pten Haplodeficiency Accelerates Liver Tumor Growth in miR-122a-Null Mice via Expansion of Periportal Hepatocyte-Like Cells.
Author:	Tu, Wei-Ling\|You, Li-Ru\|Tsou, Ann-Ping\|Chen, Chun-Ming
PMID:	30165041

380.
Journal:	Int J Biochem Cell Biol. 2018 Sep 5;104:55-65.
Title:	Fresh red raspberry phytochemicals suppress the growth of hepatocellular carcinoma cells by PTEN/AKT pathway.
Author:	Zhang, Haopeng\|Liu, Jiaren\|Li, Guodong\|Wei, Jiufeng\|Chen, Hongsheng\|Zhang, Chunpeng\|Zhao, Jinlu\|Wang, Yunfeng\|Dang, Shuwei\|Li, Xinglong\|Fang, Xuan\|Liu, Lianxin\|Liu, Ming
PMID:	30195065

381.
Journal:	J Lipid Res. 2018 Sep 10. pii: jlr.R088518.
Title:	Signaling through non-membrane nuclear phosphoinositide binding proteins in human health and disease.
Author:	Bryant, Jamal M\|Blind, Raymond D
PMID:	30201631

382.
Journal:	J Enzyme Inhib Med Chem. 2018 Dec;33(1):1352-1361.
Title:	Synthesis and cellular bioactivities of novel isoxazole derivatives incorporating an arylpiperazine moiety as anticancer agents.
Author:	Caliskan, Burcu\|Sinoplu, Esra\|Ibis, Kubra\|Akhan Guzelcan, Ece\|Cetin Atalay, Rengul\|Banoglu, Erden
PMID:	30251900

383.
Journal:	Med Sci Monit. 2018 Oct 6;24:7109-7118.
Title:	Knockdown of Ubiquitin Associated Protein 2-Like (UBAP2L) Inhibits Growth and Metastasis of Hepatocellular Carcinoma.
Author:	Li, Qian\|Wang, Wei\|Hu, Yu-Chen\|Yin, Tian-Tian\|He, Jie
PMID:	30291221

384.
Journal:	Cell Death Dis. 2018 Oct 9;9(10):1027.
Title:	Alpha-fetoprotein inhibits autophagy to promote malignant behaviour in hepatocellular carcinoma cells by activating PI3K/AKT/mTOR signalling.
Author:	Wang, Shanshan\|Zhu, Mingyue\|Wang, Qiaoyun\|Hou, Yuli\|Li, Lei\|Weng, Honglei\|Zhao, Yan\|Chen, Dexi\|Ding, Huiguo\|Guo, Junli\|Li, Mengsen
PMID:	30301886

385.
Journal:	Zhonghua Gan Zang Bing Za Zhi. 2018 Jul 20;26(7):489-494.
Title:	[The effect of miR-155 on HBV replication and PTEN expression in vivo].
Author:	Xie, C\|Ren, G L\|Xu, M C\|Zhang, W Y\|Zhang, S L\|Cai, Q Y\|Lin, Y M\|Zhou, D L
PMID:	30317769

386.
Journal:	Clin Cancer Res. 2018 Oct 16. pii: 1078-0432.CCR-18-1833.
Title:	PTEN Expression, Not Mutation Status for TSC1, TSC2 or mTOR, Correlates With Outcome on Everolimus in Patients With Renal Cell Carcinoma Treated on RECORD-3.
Author:	Voss, Martin H\|Chen, David\|Reising, Albert\|Marker, Mahtab\|Shi, Jiayuan\|Xu, Jianing\|Ostrovnaya, Irina\|Seshan, Venkatraman\|Redzematovic, Almedina\|Chen, Ying-Bei\|Patel, Parul\|Han, Xia\|Hsieh, James J\|Hakimi, A Ari\|Motzer, Robert J
PMID:	30327302

387.
Journal:	Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):E10417-E10426.
Title:	Molecular profiling of nonalcoholic fatty liver disease-associated hepatocellular carcinoma using SB transposon mutagenesis.
Author:	Kodama, Takahiro\|Yi, Jing\|Newberg, Justin Y\|Tien, Jean C\|Wu, Hao\|Finegold, Milton J\|Kodama, Michiko\|Wei, Zhubo\|Tamura, Takeshi\|Takehara, Tetsuo\|Johnson, Randy L\|Jenkins, Nancy A\|Copeland, Neal G
PMID:	30327349

388.
Journal:	Eur Rev Med Pharmacol Sci. 2018 Oct;22(19):6324-6332.
Title:	Downregulated miR-328 suppressed cell invasion and growth in hepatocellular carcinoma via targeting PTEN.
Author:	Liang, F\|Cui, Z-J\|Liu, J-D\|Liu, K-P\|Li, L\|Chen, Y-L
PMID:	30338800