Literatures

Primary Site >> Colorectal Cancer

Gene >> PTEN

1.
Journal:	J Occup Med. 1983 Mar;25(3):219-30.
Title:	Mortality among workers from a plastics producing plant: a matched case-control study nested in a retrospective cohort study.
Author:	Marsh, G M
PMID:	6682438

2.
Journal:	Semin Surg Oncol. 1998 Jan-Feb;14(1):3-12.
Title:	Molecular changes during the genesis of human gliomas.
Author:	Sehgal, A
PMID:	9407626

3.
Journal:	Am J Pathol. 1998 Aug;153(2):363-6.
Title:	Genetic pathways of colorectal carcinogenesis rarely involve the PTEN and LKB1 genes outside the inherited hamartoma syndromes.
Author:	Wang, Z J\|Taylor, F\|Churchman, M\|Norbury, G\|Tomlinson, I
PMID:	9708796

4.
Journal:	Z Arztl Fortbild Qualitatssich. 1998 Dec;92(10):705-14.
Title:	[Systematic internal quality control in surgery 1993 to 1997].
Author:	Junginger, T\|Kuchle, R\|Dutkowski, P\|Thumerer, A
PMID:	10028600

5.
Journal:	Cancer Res. 1999 Jan 15;59(2):462-6.
Title:	Causes and consequences of microsatellite instability in endometrial carcinoma.
Author:	Gurin, C C\|Federici, M G\|Kang, L\|Boyd, J
PMID:	9927063

6.
Journal:	Cancer Res. 1999 Sep 1;59(17):4170-4.
Title:	Alterations of the PPP1R3 gene in human cancer.
Author:	Kohno, T\|Takakura, S\|Yamada, T\|Okamoto, A\|Tanaka, T\|Yokota, J
PMID:	10485448

7.
Journal:	Hum Mol Genet. 2000 Jan 22;9(2):283-7.
Title:	Involvement of PTEN mutations in the genetic pathways of colorectal cancerogenesis.
Author:	Guanti, G\|Resta, N\|Simone, C\|Cariola, F\|Demma, I\|Fiorente, P\|Gentile, M
PMID:	10607839

8.
Journal:	Nature. 2000 Aug 24;406(6798):897-902.
Title:	Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kgamma.
Author:	Sasaki, T\|Irie-Sasaki, J\|Horie, Y\|Bachmaier, K\|Fata, J E\|Li, M\|Suzuki, A\|Bouchard, D\|Ho, A\|Redston, M\|Gallinger, S\|Khokha, R\|Mak, T W\|Hawkins, P T\|Stephens, L\|Scherer, S W\|Tsao, M\|Penninger, J M
PMID:	10972292

9.
Journal:	Clin Genet. 2000 Aug;58(2):89-97.
Title:	Hereditary colorectal cancer: risk assessment and management.
Author:	Hampel, H\|Peltomaki, P
PMID:	11005140

10.
Journal:	Dis Colon Rectum. 2000 Oct;43(10 Suppl):S29-33.
Title:	Analysis of the PTEN gene mutation in polyposis syndromes and sporadic gastrointestinal tumors in Japanese patients.
Author:	Negoro, K\|Takahashi, S\|Kinouchi, Y\|Takagi, S\|Hiwatashi, N\|Ichinohasama, R\|Shimosegawa, T\|Toyota, T
PMID:	11052475

11.
Journal:	J Biol Chem. 2001 Jan 12;276(2):1555-63.
Title:	Oncogenic Ki-ras confers a more aggressive colon cancer phenotype through modification of transforming growth factor-beta receptor III.
Author:	Yan, Z\|Deng, X\|Friedman, E
PMID:	11029459

12.
Journal:	Int J Oncol. 2001 Apr;18(4):817-24.
Title:	Genetic alterations and expression of the protein phosphatase 1 genes in human cancers.
Author:	Takakura, S\|Kohno, T\|Manda, R\|Okamoto, A\|Tanaka, T\|Yokota, J
PMID:	11251179

13.
Journal:	Gastroenterology. 2001 May;120(6):1381-92.
Title:	Inhibition of the phosphatidylinositol 3-kinase pathway contributes to HT29 and Caco-2 intestinal cell differentiation.
Author:	Wang, Q\|Wang, X\|Hernandez, A\|Kim, S\|Evers, B M
PMID:	11313308

14.
Journal:	Curr Biol. 2001 May 15;11(10):764-8.
Title:	Tumor suppressor and anti-inflammatory actions of PPARgamma agonists are mediated via upregulation of PTEN.
Author:	Patel, L\|Pass, I\|Coxon, P\|Downes, C P\|Smith, S A\|Macphee, C H
PMID:	11378386

15.
Journal:	J Pathol. 2001 Jul;194(3):341-8.
Title:	PTEN expression is maintained in sporadic colorectal tumours.
Author:	Taniyama, K\|Goodison, S\|Ito, R\|Bookstein, R\|Miyoshi, N\|Tahara, E\|Tarin, D\|Urquidi, V
PMID:	11439367

16.
Journal:	Acta Oncol. 2001;40(5):633-7.
Title:	Microsatellite instability, PTEN and p53 germline mutations in glioma families.
Author:	Malmer, B\|Gronberg, H\|Andersson, U\|Jonsson, B A\|Henriksson, R
PMID:	11669337

17.
Journal:	Cancer Lett. 2001 Dec 28;174(2):189-94.
Title:	PTEN gene mutations in colorectal cancers displaying microsatellite instability.
Author:	Shin, K H\|Park, Y J\|Park, J G
PMID:	11689295

18.
Journal:	Clin Cancer Res. 2001 Dec;7(12):4049-53.
Title:	Colorectal carcinomas and PTEN/MMAC1 gene mutations.
Author:	Dicuonzo, G\|Angeletti, S\|Garcia-Foncillas, J\|Brugarolas, A\|Okrouzhnov, Y\|Santini, D\|Tonini, G\|Lorino, G\|De Cesaris, M\|Baldi, A
PMID:	11751500

19.
Journal:	Hum Mol Genet. 2002 Feb 15;11(4):445-50.
Title:	Distinct PTEN mutational spectra in hereditary non-polyposis colon cancer syndrome-related endometrial carcinomas compared to sporadic microsatellite unstable tumors.
Author:	Zhou, Xiao-Ping\|Kuismanen, Shannon\|Nystrom-Lahti, Minna\|Peltomaki, Paivi\|Eng, Charis
PMID:	11854177

20.
Journal:	Oncogene. 2002 Feb 21;21(9):1450-60.
Title:	PTEN regulates tumor cell adhesion of colon carcinoma cells under dynamic conditions of fluid flow.
Author:	Haier, Jorg\|Nicolson, Garth L
PMID:	11857088

21.
Journal:	Am J Pathol. 2002 Mar;160(3):795-800.
Title:	Considerations when analyzing the methylation status of PTEN tumor suppressor gene.
Author:	Zysman, Michele A\|Chapman, William B\|Bapat, Bharati
PMID:	11891178

22.
Journal:	Am J Pathol. 2002 Jun;160(6):1953-8.
Title:	Endometrial and colorectal tumors from patients with hereditary nonpolyposis colon cancer display different patterns of microsatellite instability.
Author:	Kuismanen, Shannon A\|Moisio, Anu-Liisa\|Schweizer, Pascal\|Truninger, Kaspar\|Salovaara, Reijo\|Arola, Johanna\|Butzow, Ralf\|Jiricny, Josef\|Nystrom-Lahti, Minna\|Peltomaki, Paivi
PMID:	12057899

23.
Journal:	J Biol Chem. 2002 Sep 27;277(39):36602-10. Epub 2002 Jul 24.
Title:	Regulation of TRAIL expression by the phosphatidylinositol 3-kinase/Akt/GSK-3 pathway in human colon cancer cells.
Author:	Wang, Qingding\|Wang, Xiaofu\|Hernandez, Ambrosio\|Hellmich, Mark R\|Gatalica, Zoran\|Evers, B Mark
PMID:	12140294

24.
Journal:	J Biol Chem. 2002 Oct 11;277(41):38013-20. Epub 2002 Jul 26.
Title:	Hyaluronan oligosaccharides inhibit anchorage-independent growth of tumor cells by suppressing the phosphoinositide 3-kinase/Akt cell survival pathway.
Author:	Ghatak, Shibnath\|Misra, Suniti\|Toole, Bryan P
PMID:	12145277

25.
Journal:	Am J Pathol. 2002 Aug;161(2):439-47.
Title:	PTEN mutational spectra, expression levels, and subcellular localization in microsatellite stable and unstable colorectal cancers.
Author:	Zhou, Xiao-Ping\|Loukola, Anu\|Salovaara, Reijo\|Nystrom-Lahti, Minna\|Peltomaki, Paivi\|de la Chapelle, Albert\|Aaltonen, Lauri A\|Eng, Charis
PMID:	12163369

26.
Journal:	Gastroenterology. 2002 Oct;123(4):1163-78.
Title:	PTEN and TNF-alpha regulation of the intestinal-specific Cdx-2 homeobox gene through a PI3K, PKB/Akt, and NF-kappaB-dependent pathway.
Author:	Kim, Sunghoon\|Domon-Dell, Claire\|Wang, Qingding\|Chung, Dai H\|Di Cristofano, Antonio\|Pandolfi, Pier Paolo\|Freund, Jean-Noel\|Evers, B Mark
PMID:	12360479

27.
Journal:	Semin Oncol. 2003 Jun;30(3 Suppl 6):56-67.
Title:	Signaling inhibition with radiation in colorectal cancer: clinical trials.
Author:	McKenna, W Gillies\|Muschel, Ruth J\|Gupta, Anjali\|Hahn, Stephen\|Bernhard, Eric J
PMID:	12802796

28.
Journal:	Am J Med Genet A. 2003 Nov 1;122A(4):303-14.
Title:	Molecular dimensions of gastrointestinal tumors: some thoughts for digestion.
Author:	Cohen, M Michael Jr
PMID:	14518068

29.
Journal:	Ann Surg Oncol. 2003 Oct;10(8):876-81.
Title:	Intratumoral heterogeneity in microsatellite alterations in BRCA1 and PTEN regions in sporadic colorectal cancer.
Author:	Garcia, Jose M\|Rodriguez, Rufo\|Silva, Javier\|Munoz, Concepcion\|Dominguez, Gemma\|Silva, Jose M\|Carcereny, Enric\|Provencio, Mariano\|Espana, Pilar\|Bonilla, Felix
PMID:	14527905

30.
Journal:	Gene Ther. 2003 Nov;10(23):1961-9.
Title:	Adenovirus-mediated transfer of the PTEN gene inhibits human colorectal cancer growth in vitro and in vivo.
Author:	Saito, Y\|Swanson, X\|Mhashilkar, A M\|Oida, Y\|Schrock, R\|Branch, C D\|Chada, S\|Zumstein, L\|Ramesh, R
PMID:	14528320

31.
Journal:	Cancer Gene Ther. 2003 Nov;10(11):803-13.
Title:	Adenovirus-mediated PTEN treatment combined with caffeine produces a synergistic therapeutic effect in colorectal cancer cells.
Author:	Saito, Yuji\|Gopalan, Began\|Mhashilkar, Abner M\|Roth, Jack A\|Chada, Sunil\|Zumstein, Louis\|Ramesh, Rajagopal
PMID:	14605666

32.
Journal:	Int J Gastrointest Cancer. 2003;34(1):39-48.
Title:	Genome-wide search for loss of heterozygosity in Chinese patients with sporadic colorectal cancer.
Author:	Peng, Zhihai\|Zhang, Fang\|Zhou, Chongzhi\|Ling, Yun\|Bai, Shaochun\|Liu, Wanqing\|Qiu, Guoqiang\|He, Lin\|Wang, Liwei\|Wei, Daoyan\|Lin, Edward\|Xie, Keping
PMID:	15235134

33.
Journal:	Carcinogenesis. 2004 Feb;25(2):241-8.
Title:	Involvement of the PI 3-kinase signaling pathway in progression of colon adenocarcinoma.
Author:	Khaleghpour, Kianoush\|Li, Yang\|Banville, Denis\|Yu, Zhenbao\|Shen, Shi-Hsiang
PMID:	14578160

34.
Journal:	Oncogene. 2004 Jan 15;23(2):617-28.
Title:	PTEN mutations are common in sporadic microsatellite stable colorectal cancer.
Author:	Nassif, Najah T\|Lobo, Glenn P\|Wu, Xiaojuan\|Henderson, Christopher J A\|Morrison, Carl D\|Eng, Charis\|Jalaludin, Bin\|Segelov, Eva
PMID:	14724591

35.
Journal:	Ai Zheng. 2004 Mar;23(3):306-9.
Title:	[Expression and clinical significance of survivin gene and PTEN protein in colorectal adenocarcinoma].
Author:	Yang, Dong\|Zhu, You-Qing\|Qi, Jian
PMID:	15025964

36.
Journal:	Br J Cancer. 2004 Mar 22;90(6):1230-4.
Title:	Loss of heterozygosity on 10q and mutational status of PTEN and BMPR1A in colorectal primary tumours and metastases.
Author:	Karoui, M\|Tresallet, C\|Julie, C\|Zimmermann, U\|Staroz, F\|Brams, A\|Muti, C\|Boulard, C\|Robreau, A-M\|Puy, H\|Malafosse, R\|Penna, C\|Pruvot, F-R\|Thiery, J P\|Boileau, C\|Rougier, P\|Nordlinger, B\|Radvanyi, F\|Franc, B\|Hofmann-Radvanyi, H
PMID:	15026806

37.
Journal:	Cancer Res. 2004 Apr 1;64(7):2544-51.
Title:	Inverse PCR-based RFLP scanning identifies low-level mutation signatures in colon cells and tumors.
Author:	Liu, Wei-Hua\|Kaur, Manjit\|Wang, Gang\|Zhu, Penny\|Zhang, Yuzhi\|Makrigiorgos, G Mike
PMID:	15059910

38.
Journal:	Eksp Onkol. 2004 Mar;26(1):15-9.
Title:	Identification of a novel binding partners for tumor suppressor PTEN by a yeast two-hybrid approach.
Author:	Gorbenko, Olena\|Kuznetsov, Vitaliy\|Kukharenko, Olexandr\|Zhyvoloup, Alexandr\|Panasyuk, Ganna\|Nemazanyy, Ivan\|Filonenko, Valeriy\|Gout, Ivan
PMID:	15112574

39.
Journal:	Cancer Res. 2004 May 1;64(9):3014-21.
Title:	Frequent inactivation of PTEN by promoter hypermethylation in microsatellite instability-high sporadic colorectal cancers.
Author:	Goel, Ajay\|Arnold, Christian N\|Niedzwiecki, Donna\|Carethers, John M\|Dowell, Jeannette M\|Wasserman, Linda\|Compton, Carolyn\|Mayer, Robert J\|Bertagnolli, Monica M\|Boland, C Richard
PMID:	15126336

40.
Journal:	Breast Cancer Res. 2004;6(4):R366-71. Epub 2004 May 14.
Title:	No germline mutations in the histone acetyltransferase gene EP300 in BRCA1 and BRCA2 negative families with breast cancer and gastric, pancreatic, or colorectal cancer.
Author:	Campbell, Ian G\|Choong, David\|Chenevix-Trench, Georgia
PMID:	15217503

41.
Journal:	Biochem Biophys Res Commun. 2004 Jul 30;320(3):875-9.
Title:	NSAIDs activate PTEN and other phosphatases in human colon cancer cells: novel mechanism for chemopreventive action of NSAIDs.
Author:	Chu, Eric C\|Chai, Jianyuan\|Tarnawski, Andrzej S
PMID:	15240129

42.
Journal:	Int J Gynecol Cancer. 2004 Sep-Oct;14(5):957-65.
Title:	Molecular differences between RER+ and RER- sporadic endometrial carcinomas in a large population-based series.
Author:	Macdonald, N D\|Salvesen, H B\|Ryan, A\|Malatos, S\|Stefansson, I\|Iversen, O E\|Akslen, L A\|Das, S\|Jacobs, I J
PMID:	15361209

43.
Journal:	Curr Drug Targets Immune Endocr Metabol Disord. 2004 Sep;4(3):181-5.
Title:	Akt: a potential target for thyroid cancer therapy.
Author:	Kada, Faiza\|Saji, Motoyasu\|Ringel, Matthew D
PMID:	15379721

44.
Journal:	Ann Med. 2004;36(5):379-88.
Title:	Molecular basis and diagnostics of hereditary colorectal cancers.
Author:	Abdel-Rahman, Wael M\|Peltomaki, Paivi
PMID:	15478312

45.
Journal:	Cancer Res. 2004 Nov 1;64(21):7655-60.
Title:	PTEN up-regulates the tumor metastasis suppressor gene Drg-1 in prostate and breast cancer.
Author:	Bandyopadhyay, Sucharita\|Pai, Sudha K\|Hirota, Shigeru\|Hosobe, Sadahiro\|Tsukada, Taisei\|Miura, Kunio\|Takano, Yukio\|Saito, Ken\|Commes, Therese\|Piquemal, David\|Watabe, Misako\|Gross, Steven\|Wang, Ying\|Huggenvik, Jodi\|Watabe, Kounosuke
PMID:	15520163

46.
Journal:	World J Gastroenterol. 2004 Dec 1;10(23):3441-54.
Title:	Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis.
Author:	Xu, Xiao-Li\|Yu, Jian\|Zhang, Hong-Yu\|Sun, Meng-Hong\|Gu, Jun\|Du, Xiang\|Shi, Da-Ren\|Wang, Peng\|Yang, Zhen-Hua\|Zhu, Jing-De
PMID:	15526363

47.
Journal:	World J Gastroenterol. 2004 Dec 15;10(24):3670-3.
Title:	Inhibition of transfected PTEN on human colon cancer.
Author:	Xu, Shou-Shui\|Shen, Wen-Lu\|Ouyang, Song-Ying
PMID:	15534929

48.
Journal:	Mod Pathol. 2005 Feb;18(2):170-8.
Title:	Progressive methylation during the serrated neoplasia pathway of the colorectum.
Author:	Dong, Seung M\|Lee, Eui J\|Jeon, Eun S\|Park, Cheol K\|Kim, Kyoung-Mee
PMID:	15389252

49.
Journal:	Int J Cancer. 2005 Mar 10;114(1):58-73.
Title:	Genotype phenotype correlations in Israeli colorectal cancer patients.
Author:	Starinsky, Sigal\|Figer, Arie\|Ben-Asher, Edna\|Geva, Ravit\|Flex, Dov\|Fidder, Herma H\|Zidan, Jamal\|Lancet, Doron\|Friedman, Eitan
PMID:	15523694

50.
Journal:	Oncogene. 2005 Feb 3;24(6):1021-31.
Title:	The AKT/I kappa B kinase pathway promotes angiogenic/metastatic gene expression in colorectal cancer by activating nuclear factor-kappa B and beta-catenin.
Author:	Agarwal, Anju\|Das, Kingshuk\|Lerner, Natalia\|Sathe, Swati\|Cicek, Muzaffer\|Casey, Graham\|Sizemore, Nywana
PMID:	15592509

51.
Journal:	Cell. 2005 Jun 17;121(6):837-48.
Title:	A genetic screen for candidate tumor suppressors identifies REST.
Author:	Westbrook, Thomas F\|Martin, Eric S\|Schlabach, Michael R\|Leng, Yumei\|Liang, Anthony C\|Feng, Bin\|Zhao, Jean J\|Roberts, Thomas M\|Mandel, Gail\|Hannon, Gregory J\|Depinho, Ronald A\|Chin, Lynda\|Elledge, Stephen J
PMID:	15960972

52.
Journal:	Chin Med J (Engl). 2005 Sep 5;118(17):1477-81.
Title:	Induction of apoptosis in colorectal cancer cells by peroxisome proliferators-activated receptor gamma activation up-regulating PTEN and inhibiting PI3K activity.
Author:	Chen, Wei-chang\|Lin, Mao-song\|Bai, Xia
PMID:	16157051

53.
Journal:	Zhonghua Yi Xue Za Zhi. 2005 Aug 10;85(30):2124-7.
Title:	[Refined mapping of loss of heterzygosity on 10q23-24 in sporadic colorectal carcinoma].
Author:	Zheng, Hai-tao\|Peng, Zhi-hai\|Zhou, Chong-zhi\|Wang, Zhao-wen\|Qiu, Guo-qiang\|Zhang, Fang\|He, Lin
PMID:	16313823

54.
Journal:	Dis Colon Rectum. 2006 Mar;49(3):399-406.
Title:	Accumulation profile of frameshift mutations during development and progression of colorectal cancer from patients with hereditary nonpolyposis colorectal cancer.
Author:	Yamaguchi, Tatsuro\|Iijima, Takeru\|Mori, Takeo\|Takahashi, Keiichi\|Matsumoto, Hiroshi\|Miyamoto, Hidenori\|Hishima, Tsunekazu\|Miyaki, Michiko
PMID:	16421660

55.
Journal:	Br J Surg. 2006 Apr;93(4):395-406.
Title:	Microsatellite instability in colorectal cancer.
Author:	Soreide, K\|Janssen, E A M\|Soiland, H\|Korner, H\|Baak, J P A
PMID:	16555243

56.
Journal:	Glycobiology. 2006 Jul;16(7):573-83. Epub 2006 Mar 30.
Title:	Ganglioside GM3 modulates tumor suppressor PTEN-mediated cell cycle progression--transcriptional induction of p21(WAF1) and p27(kip1) by inhibition of PI-3K/AKT pathway.
Author:	Choi, Hee-Jung\|Chung, Tae-Wook\|Kang, Sung-Koo\|Lee, Young-Choon\|Ko, Jeong-Heon\|Kim, Jong-Guk\|Kim, Cheorl-Ho
PMID:	16574813

57.
Journal:	Am Surg. 2006 May;72(5):445-53.
Title:	Microdissection-based allelotyping: a novel technique to determine the temporal sequence and biological aggressiveness of colorectal cancer.
Author:	Gamblin, T Clark\|Finkelstein, Sydney D\|Upsal, Neil\|Kaye, Jonathan D\|Blumberg, David
PMID:	16719202

58.
Journal:	Ann Surg. 2006 Jun;243(6):833-42; discussion 843-4.
Title:	Targeted molecular therapy of the PI3K pathway: therapeutic significance of PI3K subunit targeting in colorectal carcinoma.
Author:	Rychahou, Piotr G\|Jackson, Lindsey N\|Silva, Scott R\|Rajaraman, Srinivasan\|Evers, B Mark
PMID:	16772787

59.
Journal:	Int J Gynecol Cancer. 2006 May-Jun;16(3):1419-23.
Title:	MSH2 splice site mutation and endometrial cancer.
Author:	Bianchi, F\|Rosati, S\|Belvederesi, L\|Loretelli, C\|Catalani, R\|Mandolesi, A\|Bracci, R\|Bearzi, I\|Porfiri, E\|Cellerino, R
PMID:	16803540

60.
Journal:	Int J Mol Med. 2006 Oct;18(4):643-7.
Title:	Multiple colon carcinomas in a patient with Cowden syndrome.
Author:	Bosserhoff, Anja-Katrin\|Grussendorf-Conen, Elke-Ingrid\|Rubben, Albert\|Rudnik-Schoneborn, Sabine\|Zerres, Klaus\|Buettner, Reinhard\|Merkelbach-Bruse, Sabine
PMID:	16964417

61.
Journal:	Gastroenterology. 2007 Jan;132(1):127-38.
Title:	The CpG island methylator phenotype and chromosomal instability are inversely correlated in sporadic colorectal cancer.
Author:	Goel, Ajay\|Nagasaka, Takeshi\|Arnold, Christian N\|Inoue, Toru\|Hamilton, Cody\|Niedzwiecki, Donna\|Compton, Carolyn\|Mayer, Robert J\|Goldberg, Richard\|Bertagnolli, Monica M\|Boland, C Richard
PMID:	17087942

62.
Journal:	World J Gastroenterol. 2007 Feb 7;13(5):699-708.
Title:	Survey of molecular profiling during human colon cancer development and progression by immunohistochemical staining on tissue microarray.
Author:	Chen, Wei-Chang\|Lin, Mao-Song\|Zhang, Bao-Feng\|Fang, Jing\|Zhou, Qiong\|Hu, Ying\|Gao, Heng-Jun
PMID:	17278192

63.
Journal:	Mol Cancer Res. 2007 Feb;5(2):195-201.
Title:	Phosphatidylinositol-3-OH kinase or RAS pathway mutations in human breast cancer cell lines.
Author:	Hollestelle, Antoinette\|Elstrodt, Fons\|Nagel, Jord H A\|Kallemeijn, Wouter W\|Schutte, Mieke
PMID:	17314276

64.
Journal:	Pathology. 2007 Feb;39(1):46-54.
Title:	Molecular genetic changes in epithelial, stromal and mixed neoplasms of the endometrium.
Author:	Lax, Sigurd F
PMID:	17365822

65.
Journal:	Cancer Res. 2007 Apr 1;67(7):2922-6.
Title:	PRL-3 down-regulates PTEN expression and signals through PI3K to promote epithelial-mesenchymal transition.
Author:	Wang, Haihe\|Quah, Samantha Yiling\|Dong, Jing Ming\|Manser, Edward\|Tang, Jing Ping\|Zeng, Qi
PMID:	17409395

66.
Journal:	Carcinogenesis. 2007 Dec;28(12):2476-83. Epub 2007 Aug 11.
Title:	Heterozygous disruption of the PTEN promotes intestinal neoplasia in APCmin/+ mouse: roles of osteopontin.
Author:	Shao, Jinyi\|Washington, M Kay\|Saxena, Romil\|Sheng, Hongmiao
PMID:	17693663

67.
Journal:	Cancer Res. 2007 Aug 15;67(16):7773-81.
Title:	Regulation of PTEN expression in intestinal epithelial cells by c-Jun NH2-terminal kinase activation and nuclear factor-kappaB inhibition.
Author:	Wang, Qingding\|Zhou, Yuning\|Wang, Xiaofu\|Chung, Dai H\|Evers, B Mark
PMID:	17699782

68.
Journal:	Zhonghua Zhong Liu Za Zhi. 2007 May;29(5):325-8.
Title:	[Effect of lipoteichoic acid of Bifidobacterium on survivin and its regulatory genes].
Author:	Wang, Yue\|Mai, Tao\|Liu, Ming-fang\|Chen, Shu-hui
PMID:	17892124

69.
Journal:	Cancer Res. 2007 Oct 1;67(19):9322-9.
Title:	The alternative reading frame tumor suppressor antagonizes hypoxia-induced cancer cell migration via interaction with the COOH-terminal binding protein corepressor.
Author:	Paliwal, Seema\|Kovi, Ramesh C\|Nath, Bharath\|Chen, Ya-Wen\|Lewis, Brian C\|Grossman, Steven R
PMID:	17909040

70.
Journal:	Cancer Biol Ther. 2007 Aug;6(8):1313-7.
Title:	BMP suppresses PTEN expression via RAS/ERK signaling.
Author:	Beck, Stayce E\|Carethers, John M
PMID:	18059158

71.
Journal:	Proteomics. 2008 Jan;8(1):45-61.
Title:	Transcriptome and proteome profiling of colon mucosa from quercetin fed F344 rats point to tumor preventive mechanisms, increased mitochondrial fatty acid degradation and decreased glycolysis.
Author:	Dihal, Ashwin A\|van der Woude, Hester\|Hendriksen, Peter J M\|Charif, Halima\|Dekker, Lennard J\|Ijsselstijn, Linda\|de Boer, Vincent C J\|Alink, Gerrit M\|Burgers, Peter C\|Rietjens, Ivonne M C M\|Woutersen, Ruud A\|Stierum, Rob H
PMID:	18095365

72.
Journal:	Oncogene. 2008 Jun 5;27(25):3539-45.
Title:	Clinicopathological analysis of colorectal cancers with PIK3CA mutations in Middle Eastern population.
Author:	Abubaker, J\|Bavi, P\|Al-Harbi, S\|Ibrahim, M\|Siraj, A K\|Al-Sanea, N\|Abduljabbar, A\|Ashari, L H\|Alhomoud, S\|Al-Dayel, F\|Uddin, S\|Al-Kuraya, K S
PMID:	18193083

73.
Journal:	Crit Rev Oncol Hematol. 2008 Apr;66(1):21-30.
Title:	Potential predictive markers of response to EGFR-targeted therapies in colorectal cancer.
Author:	Spano, Jean Philippe\|Milano, Gerard\|Vignot, Stephane\|Khayat, David
PMID:	18206383

74.
Journal:	Glycobiology. 2008 May;18(5):395-407.
Title:	The AP-2alpha transcription factor is required for the ganglioside GM3-stimulated transcriptional regulation of a PTEN gene.
Author:	Choi, Hee-Jung\|Chung, Tae-Wook\|Kim, Seok-Jo\|Cho, Soo-Young\|Lee, Young-Seek\|Lee, Young-Choon\|Ko, Jeong-Heon\|Kim, Cheorl-Ho
PMID:	18316341

75.
Journal:	Cancer Res. 2008 Mar 15;68(6):1953-61.
Title:	PIK3CA mutation/PTEN expression status predicts response of colon cancer cells to the epidermal growth factor receptor inhibitor cetuximab.
Author:	Jhawer, Minaxi\|Goel, Sanjay\|Wilson, Andrew J\|Montagna, Cristina\|Ling, Yi-He\|Byun, Do-Sun\|Nasser, Shannon\|Arango, Diego\|Shin, Joongho\|Klampfer, Lidija\|Augenlicht, Leonard H\|Perez-Soler, Roman\|Mariadason, John M
PMID:	18339877

76.
Journal:	Int J Cancer. 2008 Jun 15;122(12):2858-63.
Title:	Loss of XIAP sensitizes rosiglitazone-induced growth inhibition of colon cancer in vivo.
Author:	Dai, Yun\|Qiao, Liang\|Chan, Kwok Wah\|Zou, Bing\|Ma, Juan\|Lan, Hui Y\|Gu, Qing\|Li, Zesong\|Wang, Yan\|Wong, Benny L W\|Wong, Benjamin C Y
PMID:	18351648

77.
Journal:	Mol Cancer Ther. 2008 Apr;7(4):915-22.
Title:	Effects of protein kinase C modulation by PEP005, a novel ingenol angelate, on mitogen-activated protein kinase and phosphatidylinositol 3-kinase signaling in cancer cells.
Author:	Serova, Maria\|Ghoul, Aida\|Benhadji, Karim A\|Faivre, Sandrine\|Le Tourneau, Christophe\|Cvitkovic, Esteban\|Lokiec, Francois\|Lord, Janet\|Ogbourne, Steven M\|Calvo, Fabien\|Raymond, Eric
PMID:	18413805

78.
Journal:	Am J Surg. 2008 Jun;195(6):719-25.
Title:	Clinicopathological significance of PTEN loss and the phosphoinositide 3-kinase/Akt pathway in sporadic colorectal neoplasms: is PTEN loss predictor of local recurrence?
Author:	Colakoglu, Tamer\|Yildirim, Sedat\|Kayaselcuk, Fazilet\|Nursal, Tarik Zafer\|Ezer, Ali\|Noyan, Turgut\|Karakayali, Hamdi\|Haberal, Mehmet
PMID:	18440486

79.
Journal:	Clin Genet. 2008 Aug;74(2):145-54.
Title:	Variable phenotypes associated with 10q23 microdeletions involving the PTEN and BMPR1A genes.
Author:	Menko, F H\|Kneepkens, C M F\|de Leeuw, N\|Peeters, E A J\|Van Maldergem, L\|Kamsteeg, E J\|Davidson, R\|Rozendaal, L\|Lasham, C A\|Peeters-Scholte, C M P\|Jansweijer, M C\|Hilhorst-Hofstee, Y\|Gille, J J P\|Heins, Y M\|Nieuwint, A W M\|Sistermans, E A
PMID:	18510548

80.
Journal:	Mol Cancer Ther. 2008 Jun;7(6):1337-46.
Title:	In vitro differential sensitivity of melanomas to phenothiazines is based on the presence of codon 600 BRAF mutation.
Author:	Ikediobi, Ogechi N\|Reimers, Mark\|Durinck, Steffen\|Blower, Paul E\|Futreal, Andrew P\|Stratton, Michael R\|Weinstein, John N
PMID:	18524847

81.
Journal:	Carcinogenesis. 2008 Jul;29(7):1407-14.
Title:	PPARgamma is involved in mesalazine-mediated induction of apoptosis and inhibition of cell growth in colon cancer cells.
Author:	Schwab, Markus\|Reynders, Veerle\|Loitsch, Stefan\|Shastri, Yogesh M\|Steinhilber, Dieter\|Schroder, Oliver\|Stein, Jurgen
PMID:	18544567

82.
Journal:	BMC Cell Biol. 2008 Aug 1;9:43.
Title:	Single cell cytometry of protein function in RNAi treated cells and in native populations.
Author:	LaPan, Peter\|Zhang, Jing\|Pan, Jing\|Hill, Andrew\|Haney, Steven A
PMID:	18673568

83.
Journal:	BMC Cancer. 2008 Aug 13;8:234.
Title:	Potential value of PTEN in predicting cetuximab response in colorectal cancer: an exploratory study.
Author:	Razis, Evangelia\|Briasoulis, Evangelos\|Vrettou, Eleni\|Skarlos, Dimosthenis V\|Papamichael, Dimitrios\|Kostopoulos, Ioannis\|Samantas, Epaminontas\|Xanthakis, Ioannis\|Bobos, Mattheos\|Galanidi, Eleni\|Bai, Maria\|Gikonti, Ioanna\|Koukouma, Alona\|Kafiri, Georgia\|Pa
PMID:	18700047

84.
Journal:	Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):13057-62.
Title:	PTEN-deficient cancers depend on PIK3CB.
Author:	Wee, Susan\|Wiederschain, Dmitri\|Maira, Sauveur-Michel\|Loo, Alice\|Miller, Christine\|deBeaumont, Rosalie\|Stegmeier, Frank\|Yao, Yung-Mae\|Lengauer, Christoph
PMID:	18755892

85.
Journal:	Cancer Biol Ther. 2008 Oct;7(10):1694-9. Epub 2008 Oct 22.
Title:	TGFbeta modulates PTEN expression independently of SMAD signaling for growth proliferation in colon cancer cells.
Author:	Chow, Jimmy Y C\|Cabral, Jennifer A\|Chang, Jessica\|Carethers, John M
PMID:	18769113

86.
Journal:	Hum Mutat. 2008 Nov;29(11):E252-62.
Title:	Novel mutations of the suppressor gene PTEN in colorectal carcinomas stratified by microsatellite instability- and TP53 mutation- status.
Author:	Danielsen, Stine A\|Lind, Guro E\|Bjornslett, Merete\|Meling, Gunn I\|Rognum, Torleiv O\|Heim, Sverre\|Lothe, Ragnhild A
PMID:	18781614

87.
Journal:	Cancer Res. 2008 Sep 15;68(18):7270-7.
Title:	LKB1 is necessary for Akt-mediated phosphorylation of proapoptotic proteins.
Author:	Zhong, Diansheng\|Liu, Xiuju\|Khuri, Fadlo R\|Sun, Shi-Yong\|Vertino, Paula M\|Zhou, Wei
PMID:	18794113

88.
Journal:	APMIS. 2008 Sep;116(9):779-84.
Title:	Expression of NEDD4-1, a PTEN regulator, in gastric and colorectal carcinomas.
Author:	Kim, Sung Soo\|Yoo, Nam Jin\|Jeong, Eun Goo\|Kim, Min Sung\|Lee, Sug Hyung
PMID:	19024597

89.
Journal:	BMC Gastroenterol. 2008 Nov 26;8:56.
Title:	Loss of PTEN expression is associated with colorectal cancer liver metastasis and poor patient survival.
Author:	Sawai, Hirozumi\|Yasuda, Akira\|Ochi, Nobuo\|Ma, Jiachi\|Matsuo, Yoichi\|Wakasugi, Takehiro\|Takahashi, Hiroki\|Funahashi, Hitoshi\|Sato, Mikinori\|Takeyama, Hiromitsu
PMID:	19036165

90.
Journal:	Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20315-20.
Title:	Akt2 overexpression plays a critical role in the establishment of colorectal cancer metastasis.
Author:	Rychahou, Piotr G\|Kang, JungHee\|Gulhati, Pat\|Doan, Hung Q\|Chen, L Andy\|Xiao, Shu-Yuan\|Chung, Dai H\|Evers, B Mark
PMID:	19075230

91.
Journal:	Mol Cancer. 2008 Dec 31;7:94.
Title:	Gene methylation profiles of normal mucosa, and benign and malignant colorectal tumors identify early onset markers.
Author:	Ahlquist, Terje\|Lind, Guro E\|Costa, Vera L\|Meling, Gunn I\|Vatn, Morten\|Hoff, Geir S\|Rognum, Torleiv O\|Skotheim, Rolf I\|Thiis-Evensen, Espen\|Lothe, Ragnhild A
PMID:	19117505

92.
Journal:	Mol Biol (Mosk). 2008 Nov-Dec;42(6):1040-7.
Title:	[Molecular-genetic analysis of clonal intratumoral heterogeneity on colorectal adenocarcinomas].
Author:	Nemtsova, M N\|Pal'tseva, E M\|Babaian, A Iu\|Mikhailenko, D S\|Babenko, O V\|Samofalova, O Iu\|Tsar'kov, P V\|Zaletaev, D V
PMID:	19140325

93.
Journal:	Ann Oncol. 2009 Jan;20(1):84-90.
Title:	PI3KCA/PTEN deregulation contributes to impaired responses to cetuximab in metastatic colorectal cancer patients.
Author:	Perrone, F\|Lampis, A\|Orsenigo, M\|Di Bartolomeo, M\|Gevorgyan, A\|Losa, M\|Frattini, M\|Riva, C\|Andreola, S\|Bajetta, E\|Bertario, L\|Leo, E\|Pierotti, M A\|Pilotti, S
PMID:	18669866

94.
Journal:	J Clin Pathol. 2009 Sep;62(9):777-85.
Title:	Molecular pathology of endometrial carcinoma: practical aspects from the diagnostic and therapeutic viewpoints.
Author:	Llobet, D\|Pallares, J\|Yeramian, A\|Santacana, M\|Eritja, N\|Velasco, A\|Dolcet, X\|Matias-Guiu, X
PMID:	18977806

95.
Journal:	Cancer Lett. 2009 Feb 18;274(2):266-70.
Title:	Endometrial cancer and somatic G>T KRAS transversion in patients with constitutional MUTYH biallelic mutations.
Author:	Tricarico, Rossella\|Bet, Paola\|Ciambotti, Benedetta\|Di Gregorio, Carmela\|Gatteschi, Beatrice\|Gismondi, Viviana\|Toschi, Benedetta\|Tonelli, Francesco\|Varesco, Liliana\|Genuardi, Maurizio
PMID:	18980800

96.
Journal:	FASEB J. 2009 Mar;23(3):916-28.
Title:	TRIP6, a novel molecular partner of the MAGI-1 scaffolding molecule, promotes invasiveness.
Author:	Chastre, Eric\|Abdessamad, Mahmoud\|Kruglov, Alexey\|Bruyneel, Erik\|Bracke, Marc\|Di Gioia, Yolande\|Beckerle, Mary C\|van Roy, Frans\|Kotelevets, Larissa
PMID:	19017743

97.
Journal:	Eur J Cancer. 2009 May;45(7):1117-28.
Title:	Resistance to EGF-R (erbB-1) and VEGF-R modulating agents.
Author:	Dempke, Wolfram C M\|Heinemann, Volker
PMID:	19124237

98.
Journal:	Cancer Res. 2009 Mar 1;69(5):1851-7.
Title:	PIK3CA mutations in colorectal cancer are associated with clinical resistance to EGFR-targeted monoclonal antibodies.
Author:	Sartore-Bianchi, Andrea\|Martini, Miriam\|Molinari, Francesca\|Veronese, Silvio\|Nichelatti, Michele\|Artale, Salvatore\|Di Nicolantonio, Federica\|Saletti, Piercarlo\|De Dosso, Sara\|Mazzucchelli, Luca\|Frattini, Milo\|Siena, Salvatore\|Bardelli, Alberto
PMID:	19223544

99.
Journal:	Science. 2009 Mar 27;323(5922):1747-50.
Title:	A transposon-based genetic screen in mice identifies genes altered in colorectal cancer.
Author:	Starr, Timothy K\|Allaei, Raha\|Silverstein, Kevin A T\|Staggs, Rodney A\|Sarver, Aaron L\|Bergemann, Tracy L\|Gupta, Mihir\|O'Sullivan, M Gerard\|Matise, Ilze\|Dupuy, Adam J\|Collier, Lara S\|Powers, Scott\|Oberg, Ann L\|Asmann, Yan W\|Thibodeau, Stephen N\|Tessarollo,
PMID:	19251594

100.
Journal:	Br J Cancer. 2009 Apr 7;100(7):1087-94.
Title:	Differing deregulation of EGFR and downstream proteins in primary colorectal cancer and related metastatic sites may be clinically relevant.
Author:	Molinari, F\|Martin, V\|Saletti, P\|De Dosso, S\|Spitale, A\|Camponovo, A\|Bordoni, A\|Crippa, S\|Mazzucchelli, L\|Frattini, M
PMID:	19293803

101.
Journal:	Cell Death Differ. 2009 Sep;16(9):1203-14.
Title:	p38alpha blockade inhibits colorectal cancer growth in vivo by inducing a switch from HIF1alpha- to FoxO-dependent transcription.
Author:	Chiacchiera, F\|Matrone, A\|Ferrari, E\|Ingravallo, G\|Lo Sasso, G\|Murzilli, S\|Petruzzelli, M\|Salvatore, L\|Moschetta, A\|Simone, C
PMID:	19343039

102.
Journal:	Proc Natl Acad Sci U S A. 2009 Apr 28;106(17):7131-6.
Title:	Association of survival and disease progression with chromosomal instability: a genomic exploration of colorectal cancer.
Author:	Sheffer, Michal\|Bacolod, Manny D\|Zuk, Or\|Giardina, Sarah F\|Pincas, Hanna\|Barany, Francis\|Paty, Philip B\|Gerald, William L\|Notterman, Daniel A\|Domany, Eytan
PMID:	19359472

103.
Journal:	Int J Cancer. 2009 Jul 15;125(2):297-307.
Title:	Selective inhibition of proliferation in colorectal carcinoma cell lines expressing mutant APC or activated B-Raf.
Author:	Zhang, Hui-Hua\|Walker, Francesca\|Kiflemariam, Sara\|Whitehead, Robert H\|Williams, David\|Phillips, Wayne A\|Mikeska, Thomas\|Dobrovic, Alexander\|Burgess, Antony W
PMID:	19378335

104.
Journal:	Biochem Pharmacol. 2009 Sep 15;78(6):561-72.
Title:	Multiple defects in negative regulation of the PKB/Akt pathway sensitise human cancer cells to the antiproliferative effect of non-steroidal anti-inflammatory drugs.
Author:	Lincova, Eva\|Hampl, Ales\|Pernicova, Zuzana\|Starsichova, Andrea\|Krcmar, Pavel\|Machala, Miroslav\|Kozubik, Alois\|Soucek, Karel
PMID:	19433066

105.
Journal:	Hum Mol Genet. 2009 Aug 1;18(15):2851-62.
Title:	Germline and somatic cancer-associated mutations in the ATP-binding motifs of PTEN influence its subcellular localization and tumor suppressive function.
Author:	Lobo, Glenn P\|Waite, Kristin A\|Planchon, Sarah M\|Romigh, Todd\|Nassif, Najah T\|Eng, Charis
PMID:	19457929

106.
Journal:	Mod Pathol. 2009 Sep;22(9):1186-95.
Title:	Tumor-infiltrating lymphocytes in colorectal cancers with microsatellite instability are correlated with the number and spectrum of frameshift mutations.
Author:	Tougeron, David\|Fauquembergue, Emilie\|Rouquette, Alexandre\|Le Pessot, Florence\|Sesboue, Richard\|Laurent, Michele\|Berthet, Pascaline\|Mauillon, Jacques\|Di Fiore, Frederic\|Sabourin, Jean-Christophe\|Michel, Pierre\|Tosi, Mario\|Frebourg, Thierry\|Latouche, Jean-
PMID:	19503063

107.
Journal:	Autophagy. 2009 Oct;5(7):1030-3. Epub 2009 Oct 12.
Title:	Inhibition of p38alpha unveils an AMPK-FoxO3A axis linking autophagy to cancer-specific metabolism.
Author:	Chiacchiera, Fulvio\|Simone, Cristiano
PMID:	19587525

108.
Journal:	Gan To Kagaku Ryoho. 2009 Jul;36(7):1063-6.
Title:	[Status of components in EGFR-related signal transduction as predictive markers for anti-EGFR antibody therapy in colorectal cancer treatment].
Author:	Shimodaira, Hideki\|Soeda, Hiroshi\|Komine, Keigo\|Ishioka, Chikashi
PMID:	19620792

109.
Journal:	Curr Drug Targets. 2009 Oct;10(10):1033-40.
Title:	Anti-EGFR therapy in colorectal cancer: how to choose the right patient.
Author:	Meriggi, F\|Di Biasi, B\|Abeni, C\|Zaniboni, A
PMID:	19663767

110.
Journal:	World J Gastroenterol. 2009 Aug 14;15(30):3771-5.
Title:	No association between phosphatase and tensin homolog genetic polymorphisms and colon cancer.
Author:	Phillips, Lynette S\|Thompson, Cheryl L\|Merkulova, Alona\|Plummer, Sarah J\|Tucker, Thomas C\|Casey, Graham\|Li, Li
PMID:	19673018

111.
Journal:	Oncol Rep. 2009 Oct;22(4):757-64.
Title:	PTEN expression and mutation in colorectal carcinomas.
Author:	Li, Xiao-Han\|Zheng, Hua-Chuan\|Takahashi, Hiroyuki\|Masuda, Shinji\|Yang, Xiang-Hong\|Takano, Yasuo
PMID:	19724853

112.
Journal:	J Natl Cancer Inst. 2009 Oct 7;101(19):1308-24.
Title:	Biomarkers predicting clinical outcome of epidermal growth factor receptor-targeted therapy in metastatic colorectal cancer.
Author:	Siena, Salvatore\|Sartore-Bianchi, Andrea\|Di Nicolantonio, Federica\|Balfour, Julia\|Bardelli, Alberto
PMID:	19738166

113.
Journal:	Sichuan Da Xue Xue Bao Yi Xue Ban. 2009 Jul;40(4):644-6, 654.
Title:	[The relationship between PTEN expression and PI3K/AKT signal pathway in colon carcinoma].
Author:	Qi, Jian-Kang\|Huang, Xiao-Li\|Meng, Zhang-Ming\|Gan, Hua-Tian\|Fu, Dai-Gang
PMID:	19764563

114.
Journal:	Int J Oncol. 2009 Nov;35(5):977-82.
Title:	Analysis of candidate target genes for mononucleotide repeat mutation in microsatellite instability-high (MSI-H) endometrial cancer.
Author:	Kawaguchi, Makiko\|Banno, Kouji\|Yanokura, Megumi\|Kobayashi, Yusuke\|Kishimi, Arisa\|Ogawa, Seiji\|Kisu, Iori\|Nomura, Hiroyuki\|Hirasawa, Akira\|Susumu, Nobuyuki\|Aoki, Daisuke
PMID:	19787250

115.
Journal:	Cancer Res. 2009 Oct 1;69(19):7811-8.
Title:	An A13 repeat within the 3'-untranslated region of epidermal growth factor receptor (EGFR) is frequently mutated in microsatellite instability colon cancers and is associated with increased EGFR expression.
Author:	Yuan, Ziqiang\|Shin, Joongho\|Wilson, Andrew\|Goel, Sanjay\|Ling, Yi-He\|Ahmed, Naseem\|Dopeso, Higinio\|Jhawer, Minaxi\|Nasser, Shannon\|Montagna, Cristina\|Fordyce, Kenneth\|Augenlicht, Leonard H\|Aaltonen, Lauri A\|Arango, Diego\|Weber, Thomas K\|Mariadason, John M
PMID:	19789347

116.
Journal:	PLoS One. 2009 Oct 2;4(10):e7287.
Title:	Multi-determinants analysis of molecular alterations for predicting clinical benefit to EGFR-targeted monoclonal antibodies in colorectal cancer.
Author:	Sartore-Bianchi, Andrea\|Di Nicolantonio, Federica\|Nichelatti, Michele\|Molinari, Francesca\|De Dosso, Sara\|Saletti, Piercarlo\|Martini, Miriam\|Cipani, Tiziana\|Marrapese, Giovanna\|Mazzucchelli, Luca\|Lamba, Simona\|Veronese, Silvio\|Frattini, Milo\|Bardelli, Albe
PMID:	19806185

117.
Journal:	Cancer Prev Res (Phila). 2009 Nov;2(11):922-30.
Title:	Convergence of hormones, inflammation, and energy-related factors: a novel pathway of cancer etiology.
Author:	Slattery, Martha L\|Fitzpatrick, F A
PMID:	19892662

118.
Journal:	Clin Transl Oncol. 2009 Nov;11(11):737-47.
Title:	Biomarkers and anti-EGFR therapies for KRAS wild-type metastatic colorectal cancer.
Author:	Garcia-Saenz, Jose A\|Sastre, Javier\|Diaz-Rubio Garcia, Eduardo
PMID:	19917537

119.
Journal:	Gastrointest Cancer Res. 2009 Sep;3(5 Supplement 2):S73-8.
Title:	Accomplishments in 2008 in biologic markers for gastrointestinal cancers-focus on colorectal cancer.
Author:	Tejpar, Sabine\|Odze, Robert D
PMID:	20011570

120.
Journal:	Anticancer Res. 2009 Nov;29(11):4439-49.
Title:	PTEN loss induces epithelial--mesenchymal transition in human colon cancer cells.
Author:	Bowen, Kanika A\|Doan, Hung Q\|Zhou, Binhua P\|Wang, Qingding\|Zhou, Yuning\|Rychahou, Piotr G\|Evers, B Mark
PMID:	20032390

121.
Journal:	Sichuan Da Xue Xue Bao Yi Xue Ban. 2009 Nov;40(6):1021-3, 1052.
Title:	[Change from inflammation to carcinoma in ulcerative colitis: the role of PTEN/PI3K/AKT].
Author:	Fu, Dai-Gang\|Huang, Xiao-Li\|Gan, Hua-Tian\|Zhang, De-Kui\|Zhao, Li-Qiang
PMID:	20067111

122.
Journal:	Oncology. 2009;77 Suppl 1:69-74.
Title:	The dark side of the moon: the PI3K/PTEN/AKT pathway in colorectal carcinoma.
Author:	Silvestris, Nicola\|Tommasi, Stefania\|Petriella, Daniela\|Santini, Daniele\|Fistola, Ettore\|Russo, Antonio\|Numico, Gianmauro\|Tonini, Giuseppe\|Maiello, Evaristo\|Colucci, Giuseppe
PMID:	20130434

123.
Journal:	An R Acad Nac Med (Madr). 2009;126(2):243-57; discussion 258-62.
Title:	[Biomarkers and anti-EGFR therapies for KRAS wild-type tumors in metastatic colorectal cancer patients].
Author:	Diaz-Rubio Garcia, Eduardo
PMID:	20432670

124.
Journal:	Fam Cancer. 2010 Jun;9(2):125-9.
Title:	Frequent alterations of the PI3K/AKT/mTOR pathways in hereditary nonpolyposis colorectal cancer.
Author:	Ekstrand, Anna Isinger\|Jonsson, Mats\|Lindblom, Annika\|Borg, Ake\|Nilbert, Mef
PMID:	19731079

125.
Journal:	Curr Opin Gastroenterol. 2010 Jan;26(1):47-52.
Title:	Recent insights into the pathogenesis of colorectal cancer.
Author:	Goel, Ajay\|Boland, Clement Richard
PMID:	19786869

126.
Journal:	Mol Cell Biochem. 2010 Apr;337(1-2):299-305.
Title:	Identification of novel PTEN-binding partners: PTEN interaction with fatty acid binding protein FABP4.
Author:	Gorbenko, O\|Panayotou, G\|Zhyvoloup, A\|Volkova, D\|Gout, I\|Filonenko, V
PMID:	19911253

127.
Journal:	Br J Cancer. 2010 Jan 5;102(1):162-4.
Title:	PTEN status in advanced colorectal cancer treated with cetuximab.
Author:	Negri, F V\|Bozzetti, C\|Lagrasta, C A\|Crafa, P\|Bonasoni, M P\|Camisa, R\|Pedrazzi, G\|Ardizzoni, A
PMID:	19953097

128.
Journal:	Recent Pat Anticancer Drug Discov. 2010 Jun;5(2):142-51.
Title:	Anti-epidermal growth factor receptor antibodies in the treatment of metastatic colorectal cancer.
Author:	Kendall, Anne\|Lord, Rosemary\|Maisey, Nick
PMID:	19954416

129.
Journal:	Bull Cancer. 2010 Feb;97(2):E9-E15.
Title:	Coexpression of biological key modulators in primary colorectal carcinomas and related metastatic sites: implications for treatment with cetuximab.
Author:	Barbier, A\|Domont, J\|Magne, N\|Goldmard, J-L\|Genestie, C\|Hannoun, C\|Vaillant, J-C\|Bellanger, A\|Khayat, D\|Capron, F\|Spano, J-P
PMID:	20085858

130.
Journal:	Curr Cancer Drug Targets. 2010 Feb;10(1):68-79.
Title:	Molecular predictors of efficacy to anti-EGFR agents in colorectal cancer patients.
Author:	Ruzzo, Annamaria\|Graziano, Francesco\|Canestrari, Emanuele\|Magnani, Mauro
PMID:	20088793

131.
Journal:	J Clin Oncol. 2010 Mar 1;28(7):1254-61.
Title:	Molecular mechanisms of resistance to cetuximab and panitumumab in colorectal cancer.
Author:	Bardelli, Alberto\|Siena, Salvatore
PMID:	20100961

132.
Journal:	Clin Genet. 2010 Aug;78(2):162-8.
Title:	Clinical and molecular characterization of individuals with recurrent genomic disorder at 10q22.3q23.2.
Author:	Alliman, S\|Coppinger, J\|Marcadier, J\|Thiese, H\|Brock, P\|Shafer, S\|Weaver, C\|Asamoah, A\|Leppig, K\|Dyack, S\|Morash, B\|Schultz, R\|Torchia, B S\|Lamb, A N\|Bejjani, B A
PMID:	20345475

133.
Journal:	Oncogene. 2010 May 27;29(21):3033-43.
Title:	Oncogenic mutations as predictive factors in colorectal cancer.
Author:	Lievre, A\|Blons, H\|Laurent-Puig, P
PMID:	20383189

134.
Journal:	Eur J Cancer. 2010 Jul;46(11):1997-2009.
Title:	Markers for EGFR pathway activation as predictor of outcome in metastatic colorectal cancer patients treated with or without cetuximab.
Author:	Tol, Jolien\|Dijkstra, Jeroen R\|Klomp, Marjolein\|Teerenstra, Steven\|Dommerholt, Martin\|Vink-Borger, M Elisa\|van Cleef, Patricia H\|van Krieken, J Han\|Punt, Cornelis J A\|Nagtegaal, Iris D
PMID:	20413299

135.
Journal:	Recent Pat DNA Gene Seq. 2010 Jun;4(2):86-93.
Title:	Recent patents and advances in genomic biomarker discovery for colorectal cancers.
Author:	Quyun, Chen\|Ye, Zhiyun\|Lin, Sheng-Cai\|Lin, Biaoyang
PMID:	20426761

136.
Journal:	Cancer Res. 2010 Jul 1;70(13):5507-17.
Title:	The phosphoinositide 3-kinase inhibitor PI-103 downregulates choline kinase alpha leading to phosphocholine and total choline decrease detected by magnetic resonance spectroscopy.
Author:	Al-Saffar, Nada M S\|Jackson, L Elizabeth\|Raynaud, Florence I\|Clarke, Paul A\|Ramirez de Molina, Ana\|Lacal, Juan C\|Workman, Paul\|Leach, Martin O
PMID:	20551061

137.
Journal:	FASEB J. 2010 Nov;24(11):4291-301.
Title:	Thymosin beta4 targeting impairs tumorigenic activity of colon cancer stem cells.
Author:	Ricci-Vitiani, Lucia\|Mollinari, Cristiana\|di Martino, Simona\|Biffoni, Mauro\|Pilozzi, Emanuela\|Pagliuca, Alfredo\|de Stefano, Maria Chiara\|Circo, Rita\|Merlo, Daniela\|De Maria, Ruggero\|Garaci, Enrico
PMID:	20566622

138.
Journal:	Gastroenterology. 2010 Dec;139(6):1927-33.
Title:	Frequent gastrointestinal polyps and colorectal adenocarcinomas in a prospective series of PTEN mutation carriers.
Author:	Heald, Brandie\|Mester, Jessica\|Rybicki, Lisa\|Orloff, Mohammed S\|Burke, Carol A\|Eng, Charis
PMID:	20600018

139.
Journal:	Carcinogenesis. 2010 Sep;31(9):1604-11.
Title:	Genetic variation in a metabolic signaling pathway and colon and rectal cancer risk: mTOR, PTEN, STK11, RPKAA1, PRKAG2, TSC1, TSC2, PI3K and Akt1.
Author:	Slattery, Martha L\|Herrick, Jennifer S\|Lundgreen, Abbie\|Fitzpatrick, Francis A\|Curtin, Karen\|Wolff, Roger K
PMID:	20622004

140.
Journal:	Cancer Sci. 2010 Sep;101(9):2033-8.
Title:	Sprouty2 protein enhances the response to gefitinib through epidermal growth factor receptor in colon cancer cells.
Author:	Feng, Yin-Hsun\|Tsao, Chao-Jung\|Wu, Chao-Liang\|Chang, Jan-Gowth\|Lu, Pei-Jung\|Yeh, Kun-Tu\|Shieh, Gia-Shing\|Shiau, Ai-Li\|Lee, Jeng-Chang
PMID:	20624167

141.
Journal:	Biochem Pharmacol. 2010 Dec 15;80(12):2057-65.
Title:	Resveratrol modulates the levels of microRNAs targeting genes encoding tumor-suppressors and effectors of TGFbeta signaling pathway in SW480 cells.
Author:	Tili, Esmerina\|Michaille, Jean-Jacques\|Alder, Hansjuerg\|Volinia, Stefano\|Delmas, Dominique\|Latruffe, Norbert\|Croce, Carlo M
PMID:	20637737

142.
Journal:	Int J Mol Med. 2010 Sep;26(3):341-9.
Title:	Astragalus saponins modulate mTOR and ERK signaling to promote apoptosis through the extrinsic pathway in HT-29 colon cancer cells.
Author:	Auyeung, Kathy Ka-Wai\|Mok, Nga-Lai\|Wong, Ching-Man\|Cho, Chi-Hin\|Ko, Joshua Ka-Shun
PMID:	20664949

143.
Journal:	Curr Cancer Drug Targets. 2010 Dec;10(8):813-23.
Title:	KRAS mutation testing of colorectal cancer for anti-EGFR therapy: dogmas versus evidence.
Author:	Timar, Jozsef\|Hegedus, Balazs\|Raso, Erzsebet
PMID:	20718705

144.
Journal:	Curr Cancer Drug Targets. 2010 Dec;10(8):799-812.
Title:	Predictive molecular markers of response to epidermal growth factor receptor(EGFR) family-targeted therapies.
Author:	Barton, Sarah\|Starling, Naureen\|Swanton, Charles
PMID:	20718710

145.
Journal:	Oncogene. 2010 Dec 9;29(49):6418-27.
Title:	Defining the role of APC in the mitotic spindle checkpoint in vivo: APC-deficient cells are resistant to Taxol.
Author:	Radulescu, S\|Ridgway, R A\|Appleton, P\|Kroboth, K\|Patel, S\|Woodgett, J\|Taylor, S\|Nathke, I S\|Sansom, O J
PMID:	20729907

146.
Journal:	PLoS One. 2010 Nov 12;5(11):e13978.
Title:	DNA sequence profiles of the colorectal cancer critical gene set KRAS-BRAF-PIK3CA-PTEN-TP53 related to age at disease onset.
Author:	Berg, Marianne\|Danielsen, Stine A\|Ahlquist, Terje\|Merok, Marianne A\|Agesen, Trude H\|Vatn, Morten H\|Mala, Tom\|Sjo, Ole H\|Bakka, Arne\|Moberg, Ingvild\|Fetveit, Torunn\|Mathisen, Oystein\|Husby, Anders\|Sandvik, Oddvar\|Nesbakken, Arild\|Thiis-Evensen, Espen\|Lothe
PMID:	21103049

147.
Journal:	Cancer Res. 2010 Dec 1;70(23):9570-80.
Title:	MicroRNA miR-183 functions as an oncogene by targeting the transcription factor EGR1 and promoting tumor cell migration.
Author:	Sarver, Aaron L\|Li, Lihua\|Subramanian, Subbaya
PMID:	21118966

148.
Journal:	Br J Cancer. 2010 Dec 7;103(12):1765-72.
Title:	Molecular determinants of anti-EGFR sensitivity and resistance in metastatic colorectal cancer.
Author:	Di Fiore, F\|Sesboue, R\|Michel, P\|Sabourin, J C\|Frebourg, T
PMID:	21139621

149.
Journal:	World J Gastroenterol. 2010 Dec 14;16(46):5881-8.
Title:	Impact of KRAS mutation and PTEN expression on cetuximab-treated colorectal cancer.
Author:	Li, Fang-Hua\|Shen, Lin\|Li, Zhuang-Hua\|Luo, Hui-Yan\|Qiu, Miao-Zhen\|Zhang, Hui-Zhong\|Li, Yu-Hong\|Xu, Rui-Hua
PMID:	21155011

150.
Journal:	Zhonghua Yi Xue Za Zhi. 2010 Oct 19;90(38):2684-8.
Title:	[Expression of phosphatase and tensin homolog in lower rectal cancer on neoadjuvant chemoradiotherapy].
Author:	Jin, Jian-hua\|Rong, Ya-xiong\|Wang, Fang\|Xu, Xi-yuan\|Lu, Wen-bin\|Li, Xian-wen\|Deng, Jian-zhong\|Zhang, Hua\|Xu, Xue-zhong\|Xue, Zhi-xin
PMID:	21162897

151.
Journal:	PLoS One. 2010 Dec 23;5(12):e15742.
Title:	The PTEN phosphatase controls intestinal epithelial cell polarity and barrier function: role in colorectal cancer progression.
Author:	Langlois, Marie-Josee\|Bergeron, Sebastien\|Bernatchez, Gerald\|Boudreau, Francois\|Saucier, Caroline\|Perreault, Nathalie\|Carrier, Julie C\|Rivard, Nathalie
PMID:	21203412

152.
Journal:	Oncology. 2010;79(3-4):278-82.
Title:	Clinical significance of genetic variations in the PI3K/PTEN/AKT/mTOR pathway in Korean patients with colorectal cancer.
Author:	Kim, Jong Gwang\|Chae, Yee Soo\|Sohn, Sang Kyun\|Kang, Byung Woog\|Moon, Joon Ho\|Lee, Soo Jung\|Jeon, Seong Woo\|Park, Jun Seok\|Park, Jin Young\|Choi, Gyu Seog
PMID:	21412012

153.
Journal:	Apoptosis. 2011 Jan;16(1):35-44.
Title:	Mdm2 inhibition induces apoptosis in p53 deficient human colon cancer cells by activating p73- and E2F1-mediated expression of PUMA and Siva-1.
Author:	Ray, Ramesh M\|Bhattacharya, Sujoy\|Johnson, Leonard R
PMID:	20812030

154.
Journal:	Int J Cancer. 2011 Jun 15;128(12):2938-46.
Title:	EGFR and HER3 mRNA expression levels predict distant metastases in locally advanced rectal cancer.
Author:	Ho-Pun-Cheung, Alexandre\|Assenat, Eric\|Bascoul-Mollevi, Caroline\|Bibeau, Frederic\|Boissiere-Michot, Florence\|Cellier, Dominic\|Azria, David\|Rouanet, Philippe\|Senesse, Pierre\|Ychou, Marc\|Lopez-Crapez, Evelyne
PMID:	20824716

155.
Journal:	Cancer. 2011 Feb 1;117(3):492-500.
Title:	Evidence for an hMSH3 defect in familial hamartomatous polyps.
Author:	Huang, Sherry C\|Lee, Jeffrey K\|Smith, E Julieta\|Doctolero, Ryan T\|Tajima, Akihiro\|Beck, Stayce E\|Weidner, Noel\|Carethers, John M
PMID:	20845481

156.
Journal:	Gastroenterology. 2011 Jan;140(1):297-309.
Title:	Bone morphogenetic protein 4 induces differentiation of colorectal cancer stem cells and increases their response to chemotherapy in mice.
Author:	Lombardo, Ylenia\|Scopelliti, Alessandro\|Cammareri, Patrizia\|Todaro, Matilde\|Iovino, Flora\|Ricci-Vitiani, Lucia\|Gulotta, Gaspare\|Dieli, Francesco\|de Maria, Ruggero\|Stassi, Giorgio
PMID:	20951698

157.
Journal:	Cancer Biol Ther. 2011 Jan 1;11(1):111-21. Epub 2011 Jan 1.
Title:	Deregulated expression of sprouty2 and microRNA-21 in human colon cancer: Correlation with the clinical stage of the disease.
Author:	Feng, Yin-Hsun\|Wu, Chao-Liang\|Tsao, Chao-Jung\|Chang, Jan-Gowth\|Lu, Pei-Jung\|Yeh, Kun-Tu\|Uen, Yih-Huei\|Lee, Jeng-Chang\|Shiau, Ai-Li
PMID:	21099344

158.
Journal:	Br J Cancer. 2011 Jan 4;104(1):146-54.
Title:	Regulation of PTEN expression by the SWI/SNF chromatin-remodelling protein BRG1 in human colorectal carcinoma cells.
Author:	Watanabe, T\|Semba, S\|Yokozaki, H
PMID:	21102582

159.
Journal:	Fam Cancer. 2011 Jun;10(2):239-43.
Title:	Deranged Wnt signaling is frequent in hereditary nonpolyposis colorectal cancer.
Author:	Isinger-Ekstrand, Anna\|Therkildsen, Christina\|Bernstein, Inge\|Nilbert, Mef
PMID:	21132538

160.
Journal:	Lancet Oncol. 2011 Jun;12(6):594-603.
Title:	KRAS, BRAF, PIK3CA, and PTEN mutations: implications for targeted therapies in metastatic colorectal cancer.
Author:	De Roock, Wendy\|De Vriendt, Veerle\|Normanno, Nicola\|Ciardiello, Fortunato\|Tejpar, Sabine
PMID:	21163703

161.
Journal:	Eur J Surg Oncol. 2011 Feb;37(2):140-7.
Title:	Clinical significance of tumor suppressor PTEN in colorectal carcinoma.
Author:	Hsu, C P\|Kao, T Y\|Chang, W L\|Nieh, S\|Wang, H L\|Chung, Y C
PMID:	21194879

162.
Journal:	PLoS One. 2011 Jan 20;6(1):e15980.
Title:	Impact of KRAS, BRAF, PIK3CA mutations, PTEN, AREG, EREG expression and skin rash in >/= 2 line cetuximab-based therapy of colorectal cancer patients.
Author:	Saridaki, Zacharenia\|Tzardi, Maria\|Papadaki, Chara\|Sfakianaki, Maria\|Pega, Fraga\|Kalikaki, Aristea\|Tsakalaki, Eleftheria\|Trypaki, Maria\|Messaritakis, Ippokratis\|Stathopoulos, Efstathios\|Mavroudis, Dimitris\|Georgoulias, Vassilis\|Souglakos, John
PMID:	21283802

163.
Journal:	Cancer Chemother Pharmacol. 2011 Oct;68(4):871-8.
Title:	Cetuximab enhances the activities of irinotecan on gastric cancer cell lines through downregulating the EGFR pathway upregulated by irinotecan.
Author:	Liu, Xin\|Guo, Wei-Jian\|Zhang, Xiao-Wei\|Cai, Xu\|Tian, Shu\|Li, Jin
PMID:	21286718

164.
Journal:	Cancer Chemother Pharmacol. 2011 Oct;68(4):1045-55.
Title:	Analysis of KRAS, BRAF, PTEN, IGF1R, EGFR intron 1 CA status in both primary tumors and paired metastases in determining benefit from cetuximab therapy in colon cancer.
Author:	Park, Jin Hyun\|Han, Sae-Won\|Oh, Do-Youn\|Im, Seock-Ah\|Jeong, Seung-Yong\|Park, Kyu Joo\|Kim, Tae-You\|Bang, Yung-Jue\|Park, Jae-Gahb
PMID:	21340604

165.
Journal:	BMC Med Genet. 2011 Mar 15;12:38.
Title:	Multiple primary malignancies and subtle mucocutaneous lesions associated with a novel PTEN gene mutation in a patient with Cowden syndrome: case report.
Author:	Vasovcak, Peter\|Senkerikova, Maria\|Hatlova, Jana\|Krepelova, Anna
PMID:	21406108

166.
Journal:	Cancer J. 2011 Mar-Apr;17(2):114-26.
Title:	Molecular predictors of response to chemotherapy in colorectal cancer.
Author:	Dienstmann, Rodrigo\|Vilar, Eduardo\|Tabernero, Josep
PMID:	21427555

167.
Journal:	Anticancer Res. 2011 Mar;31(3):861-9.
Title:	The endothelin axis in the metastatic process of colon carcinoma.
Author:	Sorby, Lise Aagaard\|Kleiveland, Charlotte Ramstad\|Andersen, Solveig Norheim\|Bukholm, Ida Rashida Khan\|Jacobsen, Morten Bj
PMID:	21498707

168.
Journal:	Mol Cell Biochem. 2011 Nov;357(1-2):31-8.
Title:	Overexpression of miR-22 reverses paclitaxel-induced chemoresistance through activation of PTEN signaling in p53-mutated colon cancer cells.
Author:	Li, Jian\|Zhang, Yangde\|Zhao, Jingfeng\|Kong, Fangren\|Chen, Yuxiang
PMID:	21594648

169.
Journal:	Clin Cancer Res. 2011 Jul 15;17(14):4901-14.
Title:	Increased detection sensitivity for KRAS mutations enhances the prediction of anti-EGFR monoclonal antibody resistance in metastatic colorectal cancer.
Author:	Molinari, Francesca\|Felicioni, Lara\|Buscarino, Michela\|De Dosso, Sara\|Buttitta, Fiamma\|Malatesta, Sara\|Movilia, Alessandra\|Luoni, Marco\|Boldorini, Renzo\|Alabiso, Oscar\|Girlando, Salvatore\|Soini, Barbara\|Spitale, Alessandra\|Di Nicolantonio, Federica\|Salett
PMID:	21632860

170.
Journal:	J Surg Oncol. 2011 Nov 1;104(6):661-6.
Title:	The status of EGFR-associated genes could predict the outcome and tumor response of chemo-refractory metastatic colorectal patients using cetuximab and chemotherapy.
Author:	Lin, Jen-Kou\|Lin, An-Jen\|Lin, Chun-Chi\|Lan, Yuan-Tzu\|Yang, Shung-Haur\|Li, Anna Fen-Yau\|Chang, Shih-Ching
PMID:	21671463

171.
Journal:	Clin Colorectal Cancer. 2011 Dec;10(4):325-32.
Title:	Is there a role for IGF1R and c-MET pathways in resistance to cetuximab in metastatic colorectal cancer?
Author:	Inno, Alessandro\|Di Salvatore, Mariantonietta\|Cenci, Tonia\|Martini, Maurizio\|Orlandi, Armando\|Strippoli, Antonia\|Ferrara, Anna Maria\|Bagala, Cinzia\|Cassano, Alessandra\|Larocca, Luigi Maria\|Barone, Carlo
PMID:	21729677

172.
Journal:	Oncologist. 2011;16(9):1239-49.
Title:	Concordance of predictive markers for EGFR inhibitors in primary tumors and metastases in colorectal cancer: a review.
Author:	Baas, Jara M\|Krens, Lisanne L\|Guchelaar, Henk-Jan\|Morreau, Hans\|Gelderblom, Hans
PMID:	21742964

173.
Journal:	Gan To Kagaku Ryoho. 2011 Jul;38(7):1079-83.
Title:	[Predictive biomarkers of anti-EGFR monoclonal anti-body in colorectal cancer].
Author:	Soeda, Hiroshi\|Shimodaira, Hideki\|Ishioka, Chikashi
PMID:	21772090

174.
Journal:	Transl Oncol. 2011 Aug;4(4):241-8. Epub 2011 Aug 1.
Title:	Glucose metabolism measured by [(1)(8)F]fluorodeoxyglucose positron emission tomography is independent of PTEN/AKT status in human colon carcinoma cells.
Author:	Nguyen, Quang-De\|Perumal, Meg\|Waldman, Todd A\|Aboagye, Eric O
PMID:	21804920

175.
Journal:	Gastroenterology. 2011 Nov;141(5):1749-61.e1.
Title:	Neurotensin signaling activates microRNAs-21 and -155 and Akt, promotes tumor growth in mice, and is increased in human colon tumors.
Author:	Bakirtzi, Kyriaki\|Hatziapostolou, Maria\|Karagiannides, Iordanes\|Polytarchou, Christos\|Jaeger, Savina\|Iliopoulos, Dimitrios\|Pothoulakis, Charalabos
PMID:	21806946

176.
Journal:	Semin Oncol. 2011 Aug;38(4):576-87.
Title:	Predictive molecular classifiers in colorectal cancer.
Author:	Bohanes, Pierre\|LaBonte, Melissa J\|Winder, Thomas\|Lenz, Heinz-Josef
PMID:	21810517

177.
Journal:	Rinsho Byori. 2011 Jun;59(6):598-601.
Title:	[KRAS mutation test].
Author:	Hinoda, Yuji
PMID:	21815483

178.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2011 Nov;301(5):G856-64.
Title:	Intestinal epithelial-specific PTEN inactivation results in tumor formation.
Author:	Byun, Do-Sun\|Ahmed, Naseem\|Nasser, Shannon\|Shin, Joongho\|Al-Obaidi, Sheren\|Goel, Sanjay\|Corner, Georgia A\|Wilson, Andrew J\|Flanagan, Dustin J\|Williams, David S\|Augenlicht, Leonard H\|Vincan, Elizabeth\|Mariadason, John M
PMID:	21836055

179.
Journal:	Anticancer Res. 2011 Jul;31(7):2453-9.
Title:	Oncogenic KRAS regulates miR-200c and miR-221/222 in a 3D-specific manner in colorectal cancer cells.
Author:	Tsunoda, Toshiyuki\|Takashima, Yasuo\|Yoshida, Yasuhiro\|Doi, Keiko\|Tanaka, Yoko\|Fujimoto, Takahiro\|Machida, Takashi\|Ota, Takeharu\|Koyanagi, Midori\|Kuroki, Masahide\|Sasazuki, Takehiko\|Shirasawa, Senji
PMID:	21873159

180.
Journal:	Hepatogastroenterology. 2011 Jul-Aug;58(109):1182-8.
Title:	The significance of a group of molecular markers and clinicopathological factors in identifying colorectal liver metastasis.
Author:	Wu, Jian-Hui\|Tian, Xiu-Yun\|Hao, Chun-Yi
PMID:	21937374

181.
Journal:	Nutr Cancer. 2011 Nov;63(8):1226-34.
Title:	Diet and colorectal cancer: analysis of a candidate pathway using SNPS, haplotypes, and multi-gene assessment.
Author:	Slattery, Martha L\|Lundgreen, Abbie\|Herrick, Jennifer S\|Caan, Bette J\|Potter, John D\|Wolff, Roger K
PMID:	21999454

182.
Journal:	Hepatogastroenterology. 2011 Nov-Dec;58(112):1975-82.
Title:	Influences of laparoscopic resection on expressions of metastasis genes in colorectal cancer: report of microarray analysis and literature review.
Author:	Li, Jun\|Wang, Jian-Wei\|Zheng, Shu\|Zhang, Su-Zhan\|Ding, Ke-Feng
PMID:	22024071

183.
Journal:	Sci Signal. 2011 Nov 22;4(200):pt9.
Title:	Hedgehog signaling and the Gli code in stem cells, cancer, and metastases.
Author:	Ruiz i Altaba, Ariel
PMID:	22114144

184.
Journal:	Cesk Patol. 2011 Oct;47(4):154-8.
Title:	[Molecular predictive markers of EGFR-targeted therapy in metastatic colorectal cancer].
Author:	Fabian, P\|Berkovcova, J
PMID:	22145213

185.
Journal:	Oncol Lett. 2011 Nov;2(6):1219-1224.
Title:	Expression of PPARgamma and PTEN in human colorectal cancer: An immunohistochemical study using tissue microarray methodology.
Author:	Lin, Mao Song\|Huang, Jun Xing\|Chen, Wei Chang\|Zhang, Bao Feng\|Fang, Jing\|Zhou, Qiong\|Hu, Ying\|Gao, Heng Jun
PMID:	22848291

186.
Journal:	Clin Transl Gastroenterol. 2011 Nov 17;2:e5.
Title:	Upper and Lower Gastrointestinal Findings in PTEN Mutation-Positive Cowden Syndrome Patients Participating in an Active Surveillance Program.
Author:	Levi, Zohar\|Baris, Hagit N\|Kedar, Inbal\|Niv, Yaron\|Geller, Alex\|Gal, Eyal\|Gingold, Rachel\|Morgenstern, Sara\|Baruch, Yacov\|Leach, Brandie Heald\|Bronner, Mary P\|Eng, Charis
PMID:	23238744

187.
Journal:	Clin Genet. 2012 Jun;81(6):555-62.
Title:	PTEN in colorectal cancer: a report on two Cowden syndrome patients.
Author:	Kersseboom, R\|Dubbink, H J\|Corver, W E\|van Tilburg, A J P\|Poley, J W\|van Leerdam, M E\|Atmodimedjo, P N\|van de Laar, I M B H\|Collee, J M\|Dinjens, W N M\|Morreau, H\|Wagner, A
PMID:	21291452

188.
Journal:	J Cell Physiol. 2012 May;227(5):1891-8.
Title:	The pro-apoptotic effect of quercetin in cancer cell lines requires ERbeta-dependent signals.
Author:	Bulzomi, Pamela\|Galluzzo, Paola\|Bolli, Alessandro\|Leone, Stefano\|Acconcia, Filippo\|Marino, Maria
PMID:	21732360

189.
Journal:	J Gastrointest Cancer. 2012 Sep;43(3):426-30.
Title:	Management of advanced colon cancer in a community hospital--impact of age on clinical management and survival.
Author:	Mogili, Sujatha\|Yousaf, Mobeen\|Nadaraja, Nagendra\|Woodlock, Timothy
PMID:	21796331

190.
Journal:	Clin Genet. 2012 Feb;81(2):110-6.
Title:	Juvenile polyposis and other intestinal polyposis syndromes with microdeletions of chromosome 10q22-23.
Author:	Dahdaleh, F S\|Carr, J C\|Calva, D\|Howe, J R
PMID:	21834858

191.
Journal:	Clin Exp Metastasis. 2012 Feb;29(2):123-32.
Title:	Stage-dependent differential expression of microRNAs in colorectal cancer: potential role as markers of metastatic disease.
Author:	Vickers, Michael M\|Bar, Jair\|Gorn-Hondermann, Ivan\|Yarom, Nirit\|Daneshmand, Manijeh\|Hanson, Jennifer E L\|Addison, Christina L\|Asmis, Timothy R\|Jonker, Derek J\|Maroun, Jean\|Lorimer, Ian A J\|Goss, Glenwood D\|Dimitroulakos, Jim
PMID:	22120473

192.
Journal:	Mol Cancer Ther. 2012 Mar;11(3):720-9.
Title:	Comprehensive predictive biomarker analysis for MEK inhibitor GSK1120212.
Author:	Jing, Junping\|Greshock, Joel\|Holbrook, Joanna Dawn\|Gilmartin, Aidan\|Zhang, Xiping\|McNeil, Elizabeth\|Conway, Theresa\|Moy, Christopher\|Laquerre, Sylvie\|Bachman, Kurt\|Wooster, Richard\|Degenhardt, Yan
PMID:	22169769

193.
Journal:	Clin Cancer Res. 2012 Feb 1;18(3):688-99.
Title:	Primary colorectal cancers and their subsequent hepatic metastases are genetically different: implications for selection of patients for targeted treatment.
Author:	Vermaat, Joost S\|Nijman, Isaac J\|Koudijs, Marco J\|Gerritse, Frank L\|Scherer, Stefan J\|Mokry, Michal\|Roessingh, Wijnand M\|Lansu, Nico\|de Bruijn, Ewart\|van Hillegersberg, Richard\|van Diest, Paul J\|Cuppen, Edwin\|Voest, Emile E
PMID:	22173549

194.
Journal:	Curr Cancer Drug Targets. 2012 Feb;12(2):124-31.
Title:	Analysis of the concordance in the EGFR pathway status between primary tumors and related metastases of colorectal cancer patients:implications for cancer therapy.
Author:	Cejas, P\|Lopez-Gomez, M\|Aguayo, C\|Madero, R\|Moreno-Rubio, J\|de Castro Carpeno, J\|Belda-Iniesta, C\|Barriuso, J\|Moreno Garcia, V\|Diaz, E\|Burgos, E\|Gonzalez-Baron, M\|Feliu, J
PMID:	22229245

195.
Journal:	Clin Cancer Res. 2012 Jan 15;18(2):400-7.
Title:	Lifetime cancer risks in individuals with germline PTEN mutations.
Author:	Tan, Min-Han\|Mester, Jessica L\|Ngeow, Joanne\|Rybicki, Lisa A\|Orloff, Mohammed S\|Eng, Charis
PMID:	22252256

196.
Journal:	Tumour Biol. 2012 Aug;33(4):985-94.
Title:	PAK1-dependent MAPK pathway activation is required for colorectal cancer cell proliferation.
Author:	Qing, Haitao\|Gong, Wei\|Che, Yufang\|Wang, Xinying\|Peng, Liang\|Liang, Yan\|Wang, Weifei\|Deng, Qiliang\|Zhang, Hongquan\|Jiang, Bo
PMID:	22252525

197.
Journal:	Recent Pat Anticancer Drug Discov. 2012 May 1;7(2):233-47.
Title:	Emerging role of cetuximab in the treatment of colorectal cancer.
Author:	Papa, Anselmo\|Rossi, Luigi\|Lo Russo, Giuseppe\|Giordani, Erika\|Spinelli, Gian Paolo\|Zullo, Angelo\|Petrozza, Vincenzo\|Tomao, Silverio
PMID:	22264223

198.
Journal:	Clin Colorectal Cancer. 2012 Jun;11(2):143-50.
Title:	PTEN gene expression and mutations in the PIK3CA gene as predictors of clinical benefit to anti-epidermal growth factor receptor antibody therapy in patients with KRAS wild-type metastatic colorectal cancer.
Author:	Sood, Arjun\|McClain, Danielle\|Maitra, Radhashree\|Basu-Mallick, Atrayee\|Seetharam, Raviraja\|Kaubisch, Andreas\|Rajdev, Lakshmi\|Mariadason, John M\|Tanaka, Kathryn\|Goel, Sanjay
PMID:	22285706

199.
Journal:	Int J Mol Med. 2012 May;29(5):920-6.
Title:	MicroRNA-21-mediated regulation of Sprouty2 protein expression enhances the cytotoxic effect of 5-fluorouracil and metformin in colon cancer cells.
Author:	Feng, Yin-Hsun\|Wu, Chao-Liang\|Shiau, Ai-Li\|Lee, Jenq-Chang\|Chang, Jan-Gowth\|Lu, Pei-Jung\|Tung, Chao-Ling\|Feng, Li-Yia\|Huang, Wen-Tsung\|Tsao, Chao-Jung
PMID:	22322462

200.
Journal:	Biomed Pharmacother. 2012 Jul;66(5):354-67.
Title:	Role of Sulindac and Celecoxib in the regulation of angiogenesis during the early neoplasm of colon: exploring PI3-K/PTEN/Akt pathway to the canonical Wnt/beta-catenin signaling.
Author:	Vaish, Vivek\|Sanyal, Sankar Nath
PMID:	22397759

201.
Journal:	Exp Mol Pathol. 2012 Aug;93(1):135-46.
Title:	PTEN regulates apoptotic cell death through PI3-K/Akt/GSK3beta signaling pathway in DMH induced early colon carcinogenesis in rat.
Author:	Saini, Manpreet Kaur\|Sanyal, Sankar Nath
PMID:	22561258

202.
Journal:	PLoS One. 2012;7(5):e36653.
Title:	KRAS, BRAF and PIK3CA mutations and the loss of PTEN expression in Chinese patients with colorectal cancer.
Author:	Mao, Chen\|Zhou, Junhua\|Yang, Zuyao\|Huang, Yafang\|Wu, Xinyin\|Shen, Hong\|Tang, Jinling\|Chen, Qing
PMID:	22586484

203.
Journal:	Cancer Chemother Pharmacol. 2012 Jun;69(6):1647-55.
Title:	Loss of PTEN expression as a predictor of resistance to anti-EGFR monoclonal therapy in metastatic colorectal cancer: evidence from retrospective studies.
Author:	Wang, Zhen-Hua\|Gao, Qin-Yan\|Fang, Jing-Yuan
PMID:	22610356

204.
Journal:	J Mol Med (Berl). 2012 Dec;90(12):1421-38.
Title:	Specific alterations of the microRNA transcriptome and global network structure in colorectal cancer after treatment with MAPK/ERK inhibitors.
Author:	Ragusa, Marco\|Statello, Luisa\|Maugeri, Marco\|Majorana, Alessandra\|Barbagallo, Davide\|Salito, Loredana\|Sammito, Mariangela\|Santonocito, Manuela\|Angelica, Rosario\|Cavallaro, Andrea\|Scalia, Marina\|Caltabiano, Rosario\|Privitera, Giuseppe\|Biondi, Antonio\|Di Vi
PMID:	22660396

205.
Journal:	Colorectal Dis. 2012 Sep;14(9):e562-6.
Title:	Is colorectal surveillance indicated in patients with PTEN mutations?
Author:	Nieuwenhuis, M H\|Kets, C M\|Murphy-Ryan, M\|Colas, C\|Moller, P\|Hes, F J\|Hodgson, S V\|Olderode-Berends, M J W\|Aretz, S\|Heinimann, K\|Gomez Garcia, E B\|Douglas, F\|Spigelman, A\|Timshel, S\|Lindor, N M\|Vasen, H F A
PMID:	22672595

206.
Journal:	Mol Cancer. 2012 Jun 8;11:38.
Title:	Triplex DNA-binding proteins are associated with clinical outcomes revealed by proteomic measurements in patients with colorectal cancer.
Author:	Nelson, Laura D\|Bender, Christian\|Mannsperger, Heiko\|Buergy, Daniel\|Kambakamba, Patryk\|Mudduluru, Giridhar\|Korf, Ulrike\|Hughes, Dennis\|Van Dyke, Michael W\|Allgayer, Heike
PMID:	22682314

207.
Journal:	World J Gastroenterol. 2012 Jun 7;18(21):2712-8.
Title:	Phosphatase and tensin homolog expression related to cetuximab effects in colorectal cancer patients: a meta-analysis.
Author:	Shen, Yue\|Yang, Jian\|Xu, Zhi\|Gu, Dong-Ying\|Chen, Jin-Fei
PMID:	22690082

208.
Journal:	Lung Cancer. 2012 Sep;77(3):593-9.
Title:	Expression patterns of USP22 and potential targets BMI-1, PTEN, p-AKT in non-small-cell lung cancer.
Author:	Hu, Jing\|Liu, Yan-Long\|Piao, Song-lin\|Yang, Dong-dong\|Yang, Yan-Mei\|Cai, Li
PMID:	22717106

209.
Journal:	Mol Cancer Ther. 2012 Sep;11(9):2062-71.
Title:	Molecular profiling of patients with colorectal cancer and matched targeted therapy in phase I clinical trials.
Author:	Dienstmann, Rodrigo\|Serpico, Danila\|Rodon, Jordi\|Saura, Cristina\|Macarulla, Teresa\|Elez, Elena\|Alsina, Maria\|Capdevila, Jaume\|Perez-Garcia, Jose\|Sanchez-Olle, Gessami\|Aura, Claudia\|Prudkin, Ludmila\|Landolfi, Stefania\|Hernandez-Losa, Javier\|Vivancos, Ana\|T
PMID:	22723336

210.
Journal:	Cell Signal. 2012 Oct;24(10):1940-9.
Title:	ESM-1 regulates cell growth and metastatic process through activation of NF-kappaB in colorectal cancer.
Author:	Kang, Yun Hee\|Ji, Na Young\|Han, Seung Ro\|Lee, Chung Il\|Kim, Jae Wha\|Yeom, Young Il\|Kim, Young Ho\|Chun, Ho Kyung\|Kim, Jong Wan\|Chung, Jin Woong\|Ahn, Dong Kuk\|Lee, Hee Gu\|Song, Eun Young
PMID:	22735811

211.
Journal:	Clin Transl Oncol. 2012 Oct;14(10):726-39.
Title:	Guidelines for biomarker testing in colorectal carcinoma (CRC): a national consensus of the Spanish Society of Pathology (SEAP) and the Spanish Society of Medical Oncology (SEOM).
Author:	Garcia-Alfonso, Pilar\|Salazar, Ramon\|Garcia-Foncillas, Jesus\|Musulen, Eva\|Garcia-Carbonero, Rocio\|Paya, Artemio\|Perez-Segura, Pedro\|Ramon y Cajal, Santiago\|Navarro, Samuel
PMID:	22855150

212.
Journal:	PLoS One. 2012;7(8):e42470.
Title:	Proteomic profiling of a mouse model for ovarian granulosa cell tumor identifies VCP as a highly sensitive serum tumor marker in several human cancers.
Author:	Lague, Marie-Noelle\|Romieu-Mourez, Raphaelle\|Bonneil, Eric\|Boyer, Alexandre\|Pouletty, Nicolas\|Mes-Masson, Anne-Marie\|Thibault, Pierre\|Nadeau, Marie-Eve\|Boerboom, Derek
PMID:	22870330

213.
Journal:	Clin Cancer Res. 2012 Oct 15;18(20):5796-805.
Title:	Phase I study of the antiangiogenic antibody bevacizumab and the mTOR/hypoxia-inducible factor inhibitor temsirolimus combined with liposomal doxorubicin: tolerance and biological activity.
Author:	Moroney, John\|Fu, Siqing\|Moulder, Stacy\|Falchook, Gerald\|Helgason, Thorunn\|Levenback, Charles\|Hong, David\|Naing, Aung\|Wheler, Jennifer\|Kurzrock, Razelle
PMID:	22927482

214.
Journal:	Rom J Morphol Embryol. 2012;53(3):549-56.
Title:	The prognostic value of the immunohistochemical aspects of tumor suppressor genes p53, bcl-2, PTEN and nuclear proliferative antigen Ki-67 in resected colorectal carcinoma.
Author:	Ghita, C\|Vilcea, I D\|Dumitrescu, M\|Vilcea, Alina Maria\|Mirea, C S\|Aschie, Mariana\|Vasilescu, Florina
PMID:	22990545

215.
Journal:	BMC Complement Altern Med. 2012 Sep 19;12:160.
Title:	Astragalus saponins downregulate vascular endothelial growth factor under cobalt chloride-stimulated hypoxia in colon cancer cells.
Author:	Law, Pui-Ching\|Auyeung, Kathy K\|Chan, Lok-Yi\|Ko, Joshua K
PMID:	22992293

216.
Journal:	Oncol Rep. 2012 Dec;28(6):2221-6.
Title:	microRNA-181a is associated with poor prognosis of colorectal cancer.
Author:	Nishimura, Junichi\|Handa, Rio\|Yamamoto, Hirofumi\|Tanaka, Fumiaki\|Shibata, Kohei\|Mimori, Koshi\|Takemasa, Ichiro\|Mizushima, Tsunekazu\|Ikeda, Masataka\|Sekimoto, Mitsugu\|Ishii, Hideshi\|Doki, Yuichiro\|Mori, Masaki
PMID:	23023298

217.
Journal:	Curr Med Chem. 2012;19(33):5735-44.
Title:	Signal transduction pathways of the epidermal growth factor receptor in colorectal cancer and their inhibition by small molecules.
Author:	Efferth, T
PMID:	23033949

218.
Journal:	World J Gastroenterol. 2012 Oct 7;18(37):5171-80.
Title:	KRAS mutation testing in metastatic colorectal cancer.
Author:	Tan, Cong\|Du, Xiang
PMID:	23066310

219.
Journal:	Exp Ther Med. 2012 Oct;4(4):633-639.
Title:	Relationship between expression and prognostic ability of PTEN, STAT3 and VEGF-C in colorectal cancer.
Author:	Jin, Canhui\|Wang, Aihong\|Chen, Jianmin\|Liu, Xiaomin\|Wang, Gongping
PMID:	23170117

220.
Journal:	Zhonghua Wai Ke Za Zhi. 2012 Nov;50(11):1007-10.
Title:	[A study of the relationship between the mutation of PIK3CA, PTEN and the occurrence of liver metastasis of colorectal cancer: survival analysis].
Author:	Liang, Li\|Wei, Ye\|Ren, Li\|Zhong, Yun-shi\|Xu, Jian-min
PMID:	23302486

221.
Journal:	Asian Pac J Cancer Prev. 2012;13(12):6397-401.
Title:	Analysis of PTEN, VEGF, HER2 and P53 status in determining colorectal cancer benefit from bevacizumab therapy.
Author:	Kara, Oguz\|Duman, Berna Bozkurt\|Kara, Banu\|Erdogan, Seyda\|Parsak, Cem Kaan\|Sakman, Gurhan
PMID:	23464465

222.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2012 Dec;15(12):1318-21.
Title:	[Competing endogenous RNA regulation mechanism and its role in the development and progression of colorectal cancer].
Author:	Gao, Xian-hua\|Fu, Chuan-gang\|Lao, Xin-yuan\|Tan, Zhu-jun
PMID:	23596669

223.
Journal:	Mol Carcinog. 2013 Jun;52(6):459-74.
Title:	Histone deacetylase inhibition in colorectal cancer cells reveals competing roles for members of the oncogenic miR-17-92 cluster.
Author:	Humphreys, Karen J\|Cobiac, Lynne\|Le Leu, Richard K\|Van der Hoek, Mark B\|Michael, Michael Z
PMID:	22308110

224.
Journal:	Oncogene. 2013 Mar 7;32(10):1305-15.
Title:	Rescue of glandular dysmorphogenesis in PTEN-deficient colorectal cancer epithelium by PPARgamma-targeted therapy.
Author:	Jagan, I\|Fatehullah, A\|Deevi, R K\|Bingham, V\|Campbell, F C
PMID:	22543585

225.
Journal:	Int J Colorectal Dis. 2013 Feb;28(2):283-4.
Title:	Association of epigenetic alteration in PTEN gene with colorectal cancer progression among Indian population.
Author:	Rizvi, M Moshahid Alam\|Ali, Asgar\|Mehdi, Syed Jafar\|Saluja, Sundeep Singh\|Mishra, Pramod Kumar
PMID:	22552802

226.
Journal:	Crit Rev Oncol Hematol. 2013 Jan;85(1):45-81.
Title:	Prognostic and predictive biomarkers for epidermal growth factor receptor-targeted therapy in colorectal cancer: beyond KRAS mutations.
Author:	Custodio, Ana\|Feliu, Jaime
PMID:	22647972

227.
Journal:	Int J Radiat Oncol Biol Phys. 2013 Jan 1;85(1):201-7.
Title:	KRAS mutation status and clinical outcome of preoperative chemoradiation with cetuximab in locally advanced rectal cancer: a pooled analysis of 2 phase II trials.
Author:	Kim, Sun Young\|Shim, Eun Kyung\|Yeo, Hyun Yang\|Baek, Ji Yeon\|Hong, Yong Sang\|Kim, Dae Yong\|Kim, Tae Won\|Kim, Jee Hyun\|Im, Seock-Ah\|Jung, Kyung Hae\|Chang, Hee Jin
PMID:	22672749

228.
Journal:	Mod Pathol. 2013 Feb;26(2):302-13.
Title:	Combined analysis of KRAS and PIK3CA mutations, MET and PTEN expression in primary tumors and corresponding metastases in colorectal cancer.
Author:	Voutsina, Alexandra\|Tzardi, Maria\|Kalikaki, Aristea\|Zafeiriou, Zafeiris\|Papadimitraki, Elsa\|Papadakis, Michael\|Mavroudis, Dimitris\|Georgoulias, Vassilis
PMID:	22936063

229.
Journal:	Hepatogastroenterology. 2013 Jan-Feb;60(121):32-6.
Title:	Clinical significance of MMP-7 and PTEN expression in colorectal cancer.
Author:	Bi, Zheng\|Dong, Lai-Dong\|Gu, Xiao-Meng
PMID:	22944341

230.
Journal:	Hum Pathol. 2013 Feb;44(2):199-207.
Title:	PIK3CA overexpression is a possible prognostic factor for favorable survival in ovarian clear cell carcinoma.
Author:	Abe, Azusa\|Minaguchi, Takeo\|Ochi, Hiroyuki\|Onuki, Mamiko\|Okada, Satoshi\|Matsumoto, Koji\|Satoh, Toyomi\|Oki, Akinori\|Yoshikawa, Hiroyuki
PMID:	22955107

231.
Journal:	Cell Signal. 2013 Jan;25(1):12-8.
Title:	NEDD4 is overexpressed in colorectal cancer and promotes colonic cell growth independently of the PI3K/PTEN/AKT pathway.
Author:	Eide, Peter W\|Cekaite, Lina\|Danielsen, Stine A\|Eilertsen, Ina A\|Kjenseth, Ane\|Fykerud, Tone A\|Agesen, Trude H\|Bruun, Jarle\|Rivedal, Edgar\|Lothe, Ragnhild A\|Leithe, Edward
PMID:	22974840

232.
Journal:	Antioxid Redox Signal. 2013 Apr 10;18(11):1249-62.
Title:	Aldose reductase inhibition prevents colon cancer growth by restoring phosphatase and tensin homolog through modulation of miR-21 and FOXO3a.
Author:	Saxena, Ashish\|Tammali, Ravinder\|Ramana, Kota V\|Srivastava, Satish K
PMID:	22978663

233.
Journal:	Int J Colorectal Dis. 2013 Mar;28(3):385-98.
Title:	Single-agent therapy with sorafenib or 5-FU is equally effective in human colorectal cancer xenograft--no benefit of combination therapy.
Author:	Wehler, Thomas C\|Hamdi, Swaantje\|Maderer, Annett\|Graf, Claudine\|Gockel, Ines\|Schmidtmann, Irene\|Hainz, Michael\|Berger, Martin R\|Theobald, Matthias\|Galle, Peter R\|Moehler, Markus\|Schimanski, Carl C
PMID:	22983756

234.
Journal:	J Cancer Res Clin Oncol. 2013 Feb;139(2):201-9.
Title:	KRAS p.G13D mutations are associated with sensitivity to anti-EGFR antibody treatment in colorectal cancer cell lines.
Author:	Messner, Isabelle\|Cadeddu, Giuseppe\|Huckenbeck, Wolfgang\|Knowles, Helen J\|Gabbert, Helmut E\|Baldus, Stephan E\|Schaefer, Karl-Ludwig
PMID:	23015072

235.
Journal:	Oncogene. 2013 Sep 5;32(36):4304-12.
Title:	Protein tyrosine kinase 6 protects cells from anoikis by directly phosphorylating focal adhesion kinase and activating AKT.
Author:	Zheng, Y\|Gierut, J\|Wang, Z\|Miao, J\|Asara, J M\|Tyner, A L
PMID:	23027128

236.
Journal:	Expert Opin Ther Targets. 2013 Jan;17(1):1-6.
Title:	Association between PTEN IVS4 polymorphism and development of colorectal cancer in a Turkish population.
Author:	Canbay, Emel\|Kahraman, Ozlem T\|Bugra, Dursun\|Caykara, Burcu\|Seyhan, Mehmet Fatih\|Bulut, Turker\|Yamaner, Sumer\|Ozturk, Oguz
PMID:	23062208

237.
Journal:	Hum Pathol. 2013 May;44(5):829-36.
Title:	Epidermal growth factor receptor, phosphatidylinositol-3-kinase catalytic subunit/PTEN, and KRAS/NRAS/BRAF in primary resected esophageal adenocarcinomas: loss of PTEN is associated with worse clinical outcome.
Author:	Bettstetter, Marcus\|Berezowska, Sabina\|Keller, Gisela\|Walch, Axel\|Feuchtinger, Annette\|Slotta-Huspenina, Julia\|Feith, Marcus\|Drecoll, Enken\|Hofler, Heinz\|Langer, Rupert
PMID:	23158210

238.
Journal:	Int J Oncol. 2013 Jan;42(1):219-28.
Title:	MiR-21 regulates biological behavior through the PTEN/PI-3 K/Akt signaling pathway in human colorectal cancer cells.
Author:	Xiong, Binghong\|Cheng, Yong\|Ma, Li\|Zhang, Caiquan
PMID:	23174819

239.
Journal:	Clin Cancer Res. 2013 Feb 1;19(3):657-67.
Title:	Resistance to BRAF inhibition in BRAF-mutant colon cancer can be overcome with PI3K inhibition or demethylating agents.
Author:	Mao, Muling\|Tian, Feng\|Mariadason, John M\|Tsao, Chun C\|Lemos, Robert Jr\|Dayyani, Farshid\|Gopal, Y N Vashisht\|Jiang, Zhi-Qin\|Wistuba, Ignacio I\|Tang, Xi M\|Bornman, William G\|Bollag, Gideon\|Mills, Gordon B\|Powis, Garth\|Desai, Jayesh\|Gallick, Gary E\|Davies,
PMID:	23251002

240.
Journal:	J Obstet Gynaecol Res. 2013 Apr;39(4):876-8.
Title:	Endometrial cancer in a 14-year-old girl with Cowden syndrome: a case report.
Author:	Baker, William David\|Soisson, Andrew Patrick\|Dodson, Mark Kane
PMID:	23279635

241.
Journal:	Expert Opin Biol Ther. 2013 Feb;13(2):241-55.
Title:	Optimizing treatment of metastatic colorectal cancer patients with anti-EGFR antibodies: overcoming the mechanisms of cancer cell resistance.
Author:	Troiani, Teresa\|Zappavigna, Silvia\|Martinelli, Erika\|Addeo, Santolo R\|Stiuso, Paola\|Ciardiello, Fortunato\|Caraglia, Michele
PMID:	23281932

242.
Journal:	EPMA J. 2013 Jan 28;4(1):3.
Title:	Targeted therapies in colorectal cancer-an integrative view by PPPM.
Author:	Hagan, Suzanne\|Orr, Maria C M\|Doyle, Brendan
PMID:	23356214

243.
Journal:	PLoS One. 2013;8(1):e54458.
Title:	Immunopositivity for histone macroH2A1 isoforms marks steatosis-associated hepatocellular carcinoma.
Author:	Rappa, Francesca\|Greco, Azzura\|Podrini, Christine\|Cappello, Francesco\|Foti, Michelangelo\|Bourgoin, Lucie\|Peyrou, Marion\|Marino, Arianna\|Scibetta, Nunzia\|Williams, Roger\|Mazzoccoli, Gianluigi\|Federici, Massimo\|Pazienza, Valerio\|Vinciguerra, Manlio
PMID:	23372727

244.
Journal:	Cell Death Dis. 2013 Feb 7;4:e481.
Title:	PTEN-regulated AKT/FoxO3a/Bim signaling contributes to reactive oxygen species-mediated apoptosis in selenite-treated colorectal cancer cells.
Author:	Luo, H\|Yang, Y\|Duan, J\|Wu, P\|Jiang, Q\|Xu, C
PMID:	23392169

245.
Journal:	Oncol Lett. 2013 Feb;5(2):483-488.
Title:	Analgesic-antitumor peptide induces apoptosis and inhibits the proliferation of SW480 human colon cancer cells.
Author:	Gu, Yu\|Liu, Shen-Lin\|Ju, Wen-Zheng\|Li, Chang-Yin\|Cao, Peng
PMID:	23420047

246.
Journal:	Genet Med. 2013 Jul;15(7):517-27.
Title:	Recommendations from the EGAPP Working Group: can testing of tumor tissue for mutations in EGFR pathway downstream effector genes in patients with metastatic colorectal cancer improve health outcomes by guiding decisions regarding anti-EGFR therapy?
Author:
PMID:	23429431

247.
Journal:	Hum Pathol. 2013 Aug;44(8):1524-33.
Title:	Altered PTEN function caused by deletion or gene disruption is associated with poor prognosis in rectal but not in colon cancer.
Author:	Bohn, B A\|Mina, S\|Krohn, A\|Simon, R\|Kluth, M\|Harasimowicz, S\|Quaas, A\|Bockhorn, M\|Izbicki, J R\|Sauter, G\|Marx, A\|Stahl, P R
PMID:	23465274

248.
Journal:	Int J Colorectal Dis. 2013 Aug;28(8):1107-15.
Title:	Effect of adenovirus-mediated PTEN gene on ulcerative colitis-associated colorectal cancer.
Author:	Li, Zhi\|Liu, Gong Xiang\|Liu, Yu Lan\|Chen, Xi\|Huang, Xiao Li\|Gan, Hua Tian
PMID:	23516074

249.
Journal:	PLoS One. 2013;8(3):e59563.
Title:	CD24 induces expression of the oncomir miR-21 via Src, and CD24 and Src are both post-transcriptionally downregulated by the tumor suppressor miR-34a.
Author:	Muppala, Santoshi\|Mudduluru, Giridhar\|Leupold, Jorg H\|Buergy, Daniel\|Sleeman, Jonathan P\|Allgayer, Heike
PMID:	23533633

250.
Journal:	Scand J Gastroenterol. 2013 Jun;48(6):672-8.
Title:	Exome sequencing in diagnostic evaluation of colorectal cancer predisposition in young patients.
Author:	Tanskanen, Tomas\|Gylfe, Alexandra E\|Katainen, Riku\|Taipale, Minna\|Renkonen-Sinisalo, Laura\|Mecklin, Jukka-Pekka\|Jarvinen, Heikki\|Tuupanen, Sari\|Kilpivaara, Outi\|Vahteristo, Pia\|Aaltonen, Lauri A
PMID:	23544471

251.
Journal:	Exp Cell Res. 2013 Jun 10;319(10):1463-70.
Title:	Pharmacological inhibition of polycomb repressive complex-2 activity induces apoptosis in human colon cancer stem cells.
Author:	Benoit, Yannick D\|Witherspoon, Mavee S\|Laursen, Kristian B\|Guezguez, Amel\|Beausejour, Marco\|Beaulieu, Jean-Francois\|Lipkin, Steven M\|Gudas, Lorraine J
PMID:	23588203

252.
Journal:	Mol Cancer. 2013 Apr 23;12:30.
Title:	MicroRNA-32 (miR-32) regulates phosphatase and tensin homologue (PTEN) expression and promotes growth, migration, and invasion in colorectal carcinoma cells.
Author:	Wu, Weiyun\|Yang, Jingfang\|Feng, Xiao\|Wang, Hao\|Ye, Shicai\|Yang, Pengchun\|Tan, Wenkai\|Wei, Guoli\|Zhou, Yu
PMID:	23617834

253.
Journal:	J Surg Res. 2013 Oct;184(2):755-60.
Title:	Restoration of PTEN activity decreases metastases in an orthotopic model of colon cancer.
Author:	Chowdhury, Sanjib\|Ongchin, Melanie\|Wan, Guanghua\|Sharratt, Elizabeth\|Brattain, Michael G\|Rajput, Ashwani
PMID:	23623571

254.
Journal:	Pol J Pathol. 2013 Apr;64(1):15-20.
Title:	PTEN expression profiles in colorectal adenocarcinoma and its precancerous lesions.
Author:	Waniczek, Dariusz\|Snietura, Miroslaw\|Mlynarczyk-Liszka, Joanna\|Piglowski, Wojciech\|Kopec, Agnieszka\|Lange, Dariusz\|Rudzki, Marek\|Arendt, Jerzy
PMID:	23625595

255.
Journal:	Int J Cancer. 2013 Nov;133(9):2089-101.
Title:	Antitumor activity of pimasertib, a selective MEK 1/2 inhibitor, in combination with PI3K/mTOR inhibitors or with multi-targeted kinase inhibitors in pimasertib-resistant human lung and colorectal cancer cells.
Author:	Martinelli, Erika\|Troiani, Teresa\|D'Aiuto, Elena\|Morgillo, Floriana\|Vitagliano, Donata\|Capasso, Anna\|Costantino, Sarah\|Ciuffreda, Loreta Pia\|Merolla, Francesco\|Vecchione, Loredana\|De Vriendt, Veerle\|Tejpar, Sabine\|Nappi, Anna\|Sforza, Vincenzo\|Martini, Giu
PMID:	23629727

256.
Journal:	Clin Cancer Res. 2013 Jun 15;19(12):3285-96.
Title:	PIK3CA and PTEN gene and exon mutation-specific clinicopathologic and molecular associations in colorectal cancer.
Author:	Day, Fiona L\|Jorissen, Robert N\|Lipton, Lara\|Mouradov, Dmitri\|Sakthianandeswaren, Anuratha\|Christie, Michael\|Li, Shan\|Tsui, Cary\|Tie, Jeannie\|Desai, Jayesh\|Xu, Zheng-Zhou\|Molloy, Peter\|Whitehall, Vicki\|Leggett, Barbara A\|Jones, Ian T\|McLaughlin, Stephen\|W
PMID:	23633456

257.
Journal:	Br J Cancer. 2013 May 28;108(10):2153-63.
Title:	The prognostic role of KRAS, BRAF, PIK3CA and PTEN in colorectal cancer.
Author:	Eklof, V\|Wikberg, M L\|Edin, S\|Dahlin, A M\|Jonsson, B-A\|Oberg, A\|Rutegard, J\|Palmqvist, R
PMID:	23660947

258.
Journal:	Nan Fang Yi Ke Da Xue Xue Bao. 2013 May;33(5):728-32.
Title:	[Anti-microRNA-221 enhances radiosensitivity of colorectal carcinoma cells by up-regulating PTEN].
Author:	Zhang, Xiaobin\|Sun, Kai\|Lei, Shangtong\|Zhong, Yubo\|Deng, Haijun\|Ou, Wentao\|Wu, Chengtang
PMID:	23688995

259.
Journal:	Asian Pac J Cancer Prev. 2013;14(4):2201-5.
Title:	Potential targets for prevention of colorectal cancer: a focus on PI3K/Akt/mTOR and Wnt pathways.
Author:	Pandurangan, Ashok Kumar
PMID:	23725112

260.
Journal:	PLoS One. 2013 Jun 13;8(6):e65821.
Title:	PTEN loss increases PD-L1 protein expression and affects the correlation between PD-L1 expression and clinical parameters in colorectal cancer.
Author:	Song, Minmin\|Chen, Defeng\|Lu, Biyan\|Wang, Chenliang\|Zhang, Junxiao\|Huang, Lanlan\|Wang, Xiaoyan\|Timmons, Christine L\|Hu, Jun\|Liu, Bindong\|Wu, Xiaojian\|Wang, Lei\|Wang, Jianping\|Liu, Huanliang
PMID:	23785454

261.
Journal:	Niger Med J. 2013 Mar;54(2):79-86.
Title:	Phosphatase and tensin homologue deleted on chromosome 10.
Author:	Abdulkareem, Imran Haruna\|Blair, Maria
PMID:	23798791

262.
Journal:	Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2013 Apr;30(2):359-64.
Title:	[Construction of microRNA-21 and PTEN eukaryotic expression and short hairpin RNA expression vectors].
Author:	Wu, Yiying\|Zhang, Yuanyuan\|Wan, Lihong\|Chen, Jian\|Zhou, Liming\|Wang, Xiaodong
PMID:	23858763

263.
Journal:	Biochim Biophys Acta. 2013 Nov;1830(11):5142-56.
Title:	Dolastatin, along with Celecoxib, stimulates apoptosis by a mechanism involving oxidative stress, membrane potential change and PI3-K/AKT pathway down regulation.
Author:	Piplani, Honit\|Rana, Chandan\|Vaish, Vivek\|Vaiphei, Kim\|Sanyal, S N
PMID:	23872169

264.
Journal:	Eur J Cancer. 2013 Oct;49(15):3076-82.
Title:	Feasibility of preemptive biomarker profiling for personalised early clinical drug development at a Comprehensive Cancer Center.
Author:	Wiesweg, Marcel\|Ting, Saskia\|Reis, Henning\|Worm, Karl\|Kasper, Stefan\|Tewes, Mitra\|Welt, Anja\|Richly, Heike\|Meiler, Johannes\|Bauer, Sebastian\|Hense, Jorg\|Gauler, Thomas C\|Kohler, Jens\|Eberhardt, Wilfried E\|Darwiche, Kaid\|Freitag, Lutz\|Stamatis, Georgios\|Br
PMID:	23876834

265.
Journal:	Mol Cancer Ther. 2013 Oct;12(10):2135-44.
Title:	Synthetic lethal targeting of PTEN-deficient cancer cells using selective disruption of polynucleotide kinase/phosphatase.
Author:	Mereniuk, Todd R\|El Gendy, Mohamed A M\|Mendes-Pereira, Ana M\|Lord, Christopher J\|Ghosh, Sunita\|Foley, Edan\|Ashworth, Alan\|Weinfeld, Michael
PMID:	23883586

266.
Journal:	Hered Cancer Clin Pract. 2013 Jul 25;11(1):8.
Title:	Differential expression of PTEN gene correlates with phenotypic heterogeneity in three cases of patients showing clinical manifestations of PTEN hamartoma tumour syndrome.
Author:	Paparo, Lorella\|Rossi, Giovanni Battista\|Delrio, Paolo\|Rega, Daniela\|Duraturo, Francesca\|Liccardo, Raffaella\|Debellis, Mario\|Izzo, Paola\|De Rosa, Marina
PMID:	23886400

267.
Journal:	PLoS One. 2013 Jul 24;8(7):e68543.
Title:	Difluorinated-curcumin (CDF) restores PTEN expression in colon cancer cells by down-regulating miR-21.
Author:	Roy, Sanchita\|Yu, Yingjie\|Padhye, Subhash B\|Sarkar, Fazlul H\|Majumdar, Adhip P N
PMID:	23894315

268.
Journal:	Cancer Med. 2013 Jun;2(3):277-85.
Title:	Prognostic impact and the relevance of PTEN copy number alterations in patients with advanced colorectal cancer (CRC) receiving bevacizumab.
Author:	Price, Timothy J\|Hardingham, Jennifer E\|Lee, Chee K\|Townsend, Amanda R\|Wrin, Joseph W\|Wilson, Kate\|Weickhardt, Andrew\|Simes, Robert J\|Murone, Carmel\|Tebbutt, Niall C
PMID:	23930204

269.
Journal:	Cancer Chemother Pharmacol. 2013 Sep;72(3):683-97.
Title:	Molecular and cytogenetic changes in multi-drug resistant cancer cells and their influence on new compounds testing.
Author:	Podolski-Renic, Ana\|Jadranin, Milka\|Stankovic, Tijana\|Bankovic, Jasna\|Stojkovic, Sonja\|Chiourea, Maria\|Aljancic, Ivana\|Vajs, Vlatka\|Tesevic, Vele\|Ruzdijic, Sabera\|Gagos, Sarantis\|Tanic, Nikola\|Pesic, Milica
PMID:	23934261

270.
Journal:	Virchows Arch. 2013 Oct;463(4):509-23.
Title:	Alterations in the EGFR pathway coincide in colorectal cancer and impact on prognosis.
Author:	Neumann, Jens\|Wehweck, Laura\|Maatz, Susanne\|Engel, Jutta\|Kirchner, Thomas\|Jung, Andreas
PMID:	23934607

271.
Journal:	PLoS One. 2013 Jul 23;8(7):e68817.
Title:	Genotype directed therapy in murine mismatch repair deficient tumors.
Author:	Kucherlapati, Melanie H\|Esfahani, Shadi\|Habibollahi, Peiman\|Wang, Junning\|Still, Eric R\|Bronson, Roderick T\|Mahmood, Umar\|Kucherlapati, Raju S
PMID:	23935891

272.
Journal:	Epigenetics. 2013 Aug;8(8):807-15.
Title:	Toward a comprehensive and systematic methylome signature in colorectal cancers.
Author:	Ashktorab, Hassan\|Rahi, Hamed\|Wansley, Daniel\|Varma, Sudhir\|Shokrani, Babak\|Lee, Edward\|Daremipouran, Mohammad\|Laiyemo, Adeyinka\|Goel, Ajay\|Carethers, John M\|Brim, Hassan
PMID:	23975090

273.
Journal:	APMIS. 2013 Oct;121(10):954-66.
Title:	Molecular alterations of Ras-Raf-mitogen-activated protein kinase and phosphatidylinositol 3-kinase-Akt signaling pathways in colorectal cancers from a tertiary hospital at Kuala Lumpur, Malaysia.
Author:	Yip, Wai Kien\|Choo, Chee Wei\|Leong, Vincent Ching-Shian\|Leong, Pooi Pooi\|Jabar, Mohd Faisal\|Seow, Heng Fong
PMID:	23992303

274.
Journal:	Neoplasia. 2013 Sep;15(9):1086-99.
Title:	MicroRNA-130b promotes tumor development and is associated with poor prognosis in colorectal cancer.
Author:	Colangelo, Tommaso\|Fucci, Alessandra\|Votino, Carolina\|Sabatino, Lina\|Pancione, Massimo\|Laudanna, Carmelo\|Binaschi, Monica\|Bigioni, Mario\|Maggi, Carlo Alberto\|Parente, Domenico\|Forte, Nicola\|Colantuoni, Vittorio
PMID:	24027433

275.
Journal:	Oncogenesis. 2013 Sep 16;2:e71.
Title:	Epigenetic and genetic features of 24 colon cancer cell lines.
Author:	Ahmed, D\|Eide, P W\|Eilertsen, I A\|Danielsen, S A\|Eknaes, M\|Hektoen, M\|Lind, G E\|Lothe, R A
PMID:	24042735

276.
Journal:	Mol Cancer Ther. 2013 Dec;12(12):2950-61.
Title:	BRAF V600E is a determinant of sensitivity to proteasome inhibitors.
Author:	Zecchin, Davide\|Boscaro, Valentina\|Medico, Enzo\|Barault, Ludovic\|Martini, Miriam\|Arena, Sabrina\|Cancelliere, Carlotta\|Bartolini, Alice\|Crowley, Emily H\|Bardelli, Alberto\|Gallicchio, Margherita\|Di Nicolantonio, Federica
PMID:	24107445

277.
Journal:	Genes Chromosomes Cancer. 2013 Dec;52(12):1133-40.
Title:	The relationship between and clinical significance of MicroRNA-32 and phosphatase and tensin homologue expression in colorectal cancer.
Author:	Wu, Weiyun\|Yang, Pengchun\|Feng, Xiao\|Wang, Hao\|Qiu, Yumei\|Tian, Ting\|He, Yanting\|Yu, Caiyuan\|Yang, Jingfang\|Ye, Shicai\|Zhou, Yu
PMID:	24123284

278.
Journal:	J Natl Cancer Inst. 2013 Nov 6;105(21):1607-16.
Title:	Cowden syndrome and the PTEN hamartoma tumor syndrome: systematic review and revised diagnostic criteria.
Author:	Pilarski, Robert\|Burt, Randall\|Kohlman, Wendy\|Pho, Lana\|Shannon, Kristen M\|Swisher, Elizabeth
PMID:	24136893

279.
Journal:	BMC Med Genomics. 2013 Oct 23;6:43.
Title:	Association of candidate single nucleotide polymorphisms with somatic mutation of the epidermal growth factor receptor pathway.
Author:	Wormald, Samuel\|Milla, Liz\|O'Connor, Liam
PMID:	24152305

280.
Journal:	Cancer Med. 2013 Aug;2(4):496-506.
Title:	PTEN expression is consistent in colorectal cancer primaries and metastases and associates with patient survival.
Author:	Atreya, Chloe E\|Sangale, Zaina\|Xu, Nafei\|Matli, Mary R\|Tikishvili, Eliso\|Welbourn, William\|Stone, Steven\|Shokat, Kevan M\|Warren, Robert S
PMID:	24156022

281.
Journal:	J Natl Compr Canc Netw. 2013 Sep;11 Suppl 4:S9-17.
Title:	Multigene assays in metastatic colorectal cancer.
Author:	Deeb, Kristin K\|Sram, Jakub P\|Gao, Hanlin\|Fakih, Marwan G
PMID:	24158971

282.
Journal:	World J Gastroenterol. 2013 Oct 28;19(40):6814-24.
Title:	Curcumin cytotoxicity is enhanced by PTEN disruption in colorectal cancer cells.
Author:	Chen, Lin\|Li, Wen-Feng\|Wang, Hong-Xiao\|Zhao, Hai-Na\|Tang, Jia-Jia\|Wu, Chang-Jie\|Lu, Li-Ting\|Liao, Wan-Qin\|Lu, Xin-Cheng
PMID:	24187456

283.
Journal:	Cancer Manag Res. 2013 Nov 21;5:387-400.
Title:	Personalized treatment for advanced colorectal cancer: KRAS and beyond.
Author:	Patel, Gargi Surendra\|Karapetis, Christos S
PMID:	24294007

284.
Journal:	Gut Liver. 2013 Nov;7(6):747-51.
Title:	A novel germline mutation in exon 10 of the SMAD4 gene in a familial juvenile polyposis.
Author:	Jee, Myung Jin\|Yoon, Soon Man\|Kim, Eui Joong\|Choi, Hyun-Jung\|Kim, Jong-Won\|Sung, Ro Hyun\|Han, Joung Ho\|Chae, Hee Bok\|Park, Seon Mee\|Youn, Sei Jin
PMID:	24312718

285.
Journal:	Neoplasia. 2013 Nov;15(11):1218-30.
Title:	PTEN phosphatase-independent maintenance of glandular morphology in a predictive colorectal cancer model system.
Author:	Jagan, Ishaan C\|Deevi, Ravi K\|Fatehullah, Aliya\|Topley, Rebecca\|Eves, Joshua\|Stevenson, Michael\|Loughrey, Maurice\|Arthur, Kenneth\|Campbell, Frederick Charles
PMID:	24348097

286.
Journal:	World J Gastroenterol. 2013 Dec 14;19(46):8659-70.
Title:	Synergistic effect of interleukin-10-receptor variants in a case of early-onset ulcerative colitis.
Author:	Galatola, Martina\|Miele, Erasmo\|Strisciuglio, Caterina\|Paparo, Lorella\|Rega, Daniela\|Delrio, Paolo\|Duraturo, Francesca\|Martinelli, Massimo\|Rossi, Giovanni Battista\|Staiano, Annamaria\|Izzo, Paola\|De Rosa, Marina
PMID:	24379584

287.
Journal:	World J Gastroenterol. 2013 Dec 28;19(48):9307-17.
Title:	Anti-miRNA-221 sensitizes human colorectal carcinoma cells to radiation by upregulating PTEN.
Author:	Xue, Qi\|Sun, Kai\|Deng, Hai-Jun\|Lei, Shang-Tong\|Dong, Jing-Qing\|Li, Guo-Xin
PMID:	24409057

288.
Journal:	Front Oncol. 2014 Jan 16;3:326.
Title:	Functions and Regulation of the PTEN Gene in Colorectal Cancer.
Author:	Molinari, Francesca\|Frattini, Milo
PMID:	24475377

289.
Journal:	Mol Carcinog. 2014 Feb;53 Suppl 1:E45-52.
Title:	Mutational and expressional analyses of PTEN gene in colorectal cancer from Northern India.
Author:	Ali, Asgar\|Saluja, Sundeep S\|Hajela, Krishnan\|Mishra, Pramod K\|Rizvi, Moshahid A
PMID:	23359334

290.
Journal:	Oncogene. 2014 Mar 20;33(12):1538-47.
Title:	Inactivation of TGF-beta signaling and loss of PTEN cooperate to induce colon cancer in vivo.
Author:	Yu, M\|Trobridge, P\|Wang, Y\|Kanngurn, S\|Morris, S M\|Knoblaugh, S\|Grady, W M
PMID:	23604118

291.
Journal:	Int J Cancer. 2014 Mar 1;134(5):1232-8.
Title:	Phosphatidylinositol-3-kinase pathway aberrations in gastric and colorectal cancer: meta-analysis, co-occurrence and ethnic variation.
Author:	Chong, Mei-Ling\|Loh, Marie\|Thakkar, Bhavin\|Pang, Brendan\|Iacopetta, Barry\|Soong, Richie
PMID:	23960014

292.
Journal:	Dig Dis Sci. 2014 Jan;59(1):98-107.
Title:	MicroRNA-92a functions as an oncogene in colorectal cancer by targeting PTEN.
Author:	Zhang, Guangjun\|Zhou, He\|Xiao, Huaxu\|Liu, Zuoliang\|Tian, Hongpeng\|Zhou, Tong
PMID:	24026406

293.
Journal:	Apoptosis. 2014 Jan;19(1):149-64.
Title:	Mahanine synergistically enhances cytotoxicity of 5-fluorouracil through ROS-mediated activation of PTEN and p53/p73 in colon carcinoma.
Author:	Das, Ranjita\|Bhattacharya, Kaushik\|Sarkar, Sayantani\|Samanta, Suman Kumar\|Pal, Bikas C\|Mandal, Chitra
PMID:	24052409

294.
Journal:	Cell Death Differ. 2014 Jan;21(1):146-60.
Title:	p34 is a novel regulator of the oncogenic behavior of NEDD4-1 and PTEN.
Author:	Hong, S-W\|Moon, J-H\|Kim, J-S\|Shin, J-S\|Jung, K-A\|Lee, W-K\|Jeong, S-Y\|Hwang, J J\|Lee, S-J\|Suh, Y-A\|Kim, I\|Nam, K-Y\|Han, S\|Kim, J E\|Kim, K-P\|Hong, Y S\|Lee, J-L\|Lee, W-J\|Choi, E K\|Lee, J S\|Jin, D-H\|Kim, T W
PMID:	24141722

295.
Journal:	Am J Pathol. 2014 Jan;184(1):86-91.
Title:	Epithelial-specific loss of PTEN results in colorectal juvenile polyp formation and invasive cancer.
Author:	Marsh Durban, Victoria\|Jansen, Marnix\|Davies, Emma J\|Morsink, Folkert H\|Offerhaus, G Johan A\|Clarke, Alan R
PMID:	24200851

296.
Journal:	Cancer Lett. 2014 Mar 1;344(1):110-8.
Title:	Targeted therapy against chemoresistant colorectal cancers: Inhibition of p38alpha modulates the effect of cisplatin in vitro and in vivo through the tumor suppressor FoxO3A.
Author:	Germani, Aldo\|Matrone, Antonio\|Grossi, Valentina\|Peserico, Alessia\|Sanese, Paola\|Liuzzi, Micaela\|Palermo, Rocco\|Murzilli, Stefania\|Campese, Antonio Francesco\|Ingravallo, Giuseppe\|Canettieri, Gianluca\|Tezil, Tugsan\|Simone, Cristiano
PMID:	24215867

297.
Journal:	Clin Cancer Res. 2014 Feb 1;20(3):744-53.
Title:	PIK3CA, BRAF, and PTEN status and benefit from cetuximab in the treatment of advanced colorectal cancer--results from NCIC CTG/AGITG CO.17.
Author:	Karapetis, Christos S\|Jonker, Derek\|Daneshmand, Manijeh\|Hanson, Jennifer E\|O'Callaghan, Christopher J\|Marginean, Celia\|Zalcberg, John R\|Simes, John\|Moore, Malcolm J\|Tebbutt, Niall C\|Price, Timothy J\|Shapiro, Jeremy D\|Pavlakis, Nick\|Gibbs, Peter\|Van Hazel,
PMID:	24218517

298.
Journal:	J Pathol. 2014 May;233(1):27-38.
Title:	PTEN loss and KRAS activation leads to the formation of serrated adenomas and metastatic carcinoma in the mouse intestine.
Author:	Davies, Emma J\|Marsh Durban, Victoria\|Meniel, Valerie\|Williams, Geraint T\|Clarke, Alan R
PMID:	24293351

299.
Journal:	Gynecol Oncol. 2014 Feb;132(2):506-12.
Title:	Mismatch repair deficiency in ovarian cancer -- molecular characteristics and clinical implications.
Author:	Xiao, Xue\|Melton, David W\|Gourley, Charlie
PMID:	24333356

300.
Journal:	PLoS One. 2014 Jan 8;9(1):e84627.
Title:	Fish oil suppresses cell growth and metastatic potential by regulating PTEN and NF-kappaB signaling in colorectal cancer.
Author:	Kansal, Shevali\|Bhatnagar, Archana\|Agnihotri, Navneet
PMID:	24416253

301.
Journal:	Int J Oncol. 2014 Mar;44(3):905-11.
Title:	MHY-449, a novel dihydrobenzofuro[4,5-b][1,8] naphthyridin-6-one derivative, induces apoptotic cell death through modulation of Akt/FoxO1 and ERK signaling in PC3 human prostate cancer cells.
Author:	Lee, Sun Hwa\|Kang, Yong Jung\|Sung, Bokyung\|Kim, Dong Hwan\|Lim, Hyun Sook\|Kim, Hye Rim\|Kim, Seong Jin\|Yoon, Jeong-Hyun\|Moon, Hyung Ryong\|Chung, Hae Young\|Kim, Nam Deuk
PMID:	24424889

302.
Journal:	Int J Clin Oncol. 2014 Apr;19(2):211-9.
Title:	Is biomarker research advancing in the era of personalized medicine for head and neck cancer?
Author:	Yokota, Tomoya
PMID:	24442754

303.
Journal:	Digestion. 2014;89(1):18-23.
Title:	Biomarkers for predicting the efficacy of anti-epidermal growth factor receptor antibody in the treatment of colorectal cancer.
Author:	Okada, Yasuyuki\|Miyamoto, Hiroshi\|Goji, Takahiro\|Takayama, Tetsuji
PMID:	24458108

304.
Journal:	Hum Immunol. 2014 Apr;75(4):348-53.
Title:	MiR-20b, -21, and -130b inhibit PTEN expression resulting in B7-H1 over-expression in advanced colorectal cancer.
Author:	Zhu, Jianjie\|Chen, Lanxin\|Zou, Lingting\|Yang, Panpan\|Wu, Ruirong\|Mao, Yong\|Zhou, Huan\|Li, Rui\|Wang, Kaicai\|Wang, Weipeng\|Hua, Dong\|Zhang, Xueguang
PMID:	24468585

305.
Journal:	Cancer Chemother Pharmacol. 2014 Apr;73(4):749-57.
Title:	Overexpression of MET is a new predictive marker for anti-EGFR therapy in metastatic colorectal cancer with wild-type KRAS.
Author:	Kishiki, Tomokazu\|Ohnishi, Hiroaki\|Masaki, Tadahiko\|Ohtsuka, Kouki\|Ohkura, Yasuo\|Furuse, Jyunji\|Watanabe, Takashi\|Sugiyama, Masanori
PMID:	24500024

306.
Journal:	BMC Cancer. 2014 Feb 25;14:128.
Title:	Can we accurately report PTEN status in advanced colorectal cancer?
Author:	Hocking, Christopher\|Hardingham, Jennifer E\|Broadbridge, Vy\|Wrin, Joe\|Townsend, Amanda R\|Tebbutt, Niall\|Cooper, John\|Ruszkiewicz, Andrew\|Lee, Chee\|Price, Timothy J
PMID:	24564252

307.
Journal:	World J Gastroenterol. 2014 Feb 21;20(7):1833-8.
Title:	Colonic manifestations of PTEN hamartoma tumor syndrome: case series and systematic review.
Author:	Stanich, Peter P\|Pilarski, Robert\|Rock, Jonathan\|Frankel, Wendy L\|El-Dika, Samer\|Meyer, Marty M
PMID:	24587660

308.
Journal:	J Cancer Res Clin Oncol. 2014 May;140(5):737-48.
Title:	EGFR gene gain and PTEN protein expression are favorable prognostic factors in patients with KRAS wild-type metastatic colorectal cancer treated with cetuximab.
Author:	Razis, Evangelia\|Pentheroudakis, George\|Rigakos, George\|Bobos, Mattheos\|Kouvatseas, George\|Tzaida, Olympia\|Makatsoris, Thomas\|Papakostas, Pavlos\|Bai, Maria\|Goussia, Anna\|Samantas, Epaminontas\|Papamichael, Demetrios\|Romanidou, Ourania\|Efstratiou, Ioannis\|T
PMID:	24595598

309.
Journal:	PLoS One. 2014 Mar 18;9(3):e91811.
Title:	The clinical implication of cancer-associated microvasculature and fibroblast in advanced colorectal cancer patients with synchronous or metachronous metastases.
Author:	Kwak, Yoonjin\|Lee, Hee Eun\|Kim, Woo Ho\|Kim, Duck-Woo\|Kang, Sung-Bum\|Lee, Hye Seung
PMID:	24642707

310.
Journal:	Oncol Rep. 2014 May;31(5):2236-44.
Title:	PTEN mutation, loss of heterozygosity, promoter methylation and expression in colorectal carcinoma: two hits on the gene?
Author:	Huhns, Maja\|Salem, Tareq\|Schneider, Bjorn\|Krohn, Mathias\|Linnebacher, Michael\|Prall, Friedrich
PMID:	24647592

311.
Journal:	Biomed Rep. 2014 Mar;2(2):250-254.
Title:	Aged black garlic extract inhibits HT29 colon cancer cell growth via the PI3K/Akt signaling pathway.
Author:	Dong, Menghua\|Yang, Guiqing\|Liu, Hanchen\|Liu, Xiaoxu\|Lin, Sixiang\|Sun, Dongning\|Wang, Yishan
PMID:	24649105

312.
Journal:	Am J Pathol. 2014 May;184(5):1355-68.
Title:	Quantitatively controlling expression of miR-17~92 determines colon tumor progression in a mouse tumor model.
Author:	Jiang, Hong\|Wang, Ping\|Wang, Qilong\|Wang, Baomei\|Mu, Jingyao\|Zhuang, Xiaoying\|Zhang, Lifeng\|Yan, Jun\|Miller, Donald\|Zhang, Huang-Ge
PMID:	24681249

313.
Journal:	Tumour Biol. 2014 Jul;35(7):6475-83.
Title:	The roles of miR-200c in colon cancer and associated molecular mechanisms.
Author:	Chen, Jianmei\|Wang, Weining\|Zhang, Yangde\|Hu, Tiehui\|Chen, Yuxiang
PMID:	24682933

314.
Journal:	FEBS Lett. 2014 May 2;588(9):1773-9.
Title:	miR-181a mediates metabolic shift in colon cancer cells via the PTEN/AKT pathway.
Author:	Wei, Zhonghua\|Cui, Long\|Mei, Zubing\|Liu, Min\|Zhang, Daoxiang
PMID:	24685694

315.
Journal:	Cancer Lett. 2014 Jul 10;349(1):35-44.
Title:	EGR1-dependent PTEN upregulation by 2-benzoyloxycinnamaldehyde attenuates cell invasion and EMT in colon cancer.
Author:	Kim, Jinkyung\|Kang, Hye Suk\|Lee, Yu-Jin\|Lee, Heon-Jin\|Yun, Jieun\|Shin, Jung Hyu\|Lee, Chang Woo\|Kwon, Byoung-Mog\|Hong, Su-Hyung
PMID:	24704156

316.
Journal:	Cancer Cell. 2014 Apr 14;25(4):469-83.
Title:	MicroRNA-135b promotes cancer progression by acting as a downstream effector of oncogenic pathways in colon cancer.
Author:	Valeri, Nicola\|Braconi, Chiara\|Gasparini, Pierluigi\|Murgia, Claudio\|Lampis, Andrea\|Paulus-Hock, Viola\|Hart, Jonathan R\|Ueno, Lynn\|Grivennikov, Sergei I\|Lovat, Francesca\|Paone, Alessio\|Cascione, Luciano\|Sumani, Khlea M\|Veronese, Angelo\|Fabbri, Muller\|Caras
PMID:	24735923

317.
Journal:	Int J Oncol. 2014 Jul;45(1):104-12.
Title:	The PTEN/PI3K/Akt and Wnt/beta-catenin signaling pathways are involved in the inhibitory effect of resveratrol on human colon cancer cell proliferation.
Author:	Liu, Ying-Zi\|Wu, Ke\|Huang, Jun\|Liu, Yang\|Wang, Xin\|Meng, Zi-Jun\|Yuan, Shuang-Xue\|Wang, Dong-Xu\|Luo, Jin-Yong\|Zuo, Guo-Wei\|Yin, Liang-Jun\|Chen, Liang\|Deng, Zhong-Liang\|Yang, Jun-Qin\|Sun, Wen-Juan\|He, Bai-Cheng
PMID:	24756222

318.
Journal:	Rev Recent Clin Trials. 2014;9(1):8-12.
Title:	The Emerging Role of NRAS Mutations in Colorectal Cancer Patients Selected for Anti-EGFR Therapies.
Author:	Meriggi, Fausto\|Vermi, William\|Bertocchi, Paola\|Zaniboni, Alberto
PMID:	24758538

319.
Journal:	Life Sci. 2014 Jun 13;106(1-2):19-24.
Title:	Correlation of over-expressions of miR-21 and Notch-1 in human colorectal cancer with clinical stages.
Author:	Xiong, Yao\|Zhang, Yuan-Yuan\|Wu, Yi-Ying\|Wang, Xiao-Dong\|Wan, Li-Hong\|Li, Li-\|Zhou, Li-Ming
PMID:	24780321

320.
Journal:	Int J Mol Sci. 2014 May 13;15(5):8458-72.
Title:	MicroRNA-103 promotes colorectal cancer by targeting tumor suppressor DICER and PTEN.
Author:	Geng, Li\|Sun, Bing\|Gao, Bo\|Wang, Zheng\|Quan, Cheng\|Wei, Feng\|Fang, Xue-Dong
PMID:	24828205

321.
Journal:	Carcinogenesis. 2014 Oct;35(10):2175-82.
Title:	MicroRNA-21 promotes tumour malignancy via increased nuclear translocation of beta-catenin and predicts poor outcome in APC-mutated but not in APC-wild-type colorectal cancer.
Author:	Lin, Po-Lin\|Wu, De-Wei\|Huang, Chi-Chou\|He, Tsung-Ying\|Chou, Ming-Chih\|Sheu, Gwo-Tarng\|Lee, Huei
PMID:	24832083

322.
Journal:	Oncol Rep. 2014 Jul;32(1):57-64.
Title:	Impact of genetic profiles on the efficacy of anti-EGFR antibodies in metastatic colorectal cancer with KRAS mutation.
Author:	Kishiki, Tomokazu\|Ohnishi, Hiroaki\|Masaki, Tadahiko\|Ohtsuka, Kouki\|Ohkura, Yasuo\|Furuse, Jyunji\|Sugiyama, Masanori\|Watanabe, Takashi
PMID:	24839940

323.
Journal:	Neoplasia. 2014 Apr;16(4):365-74.e1-2.
Title:	NHERF1/EBP50 controls morphogenesis of 3D colonic glands by stabilizing PTEN and ezrin-radixin-moesin proteins at the apical membrane.
Author:	Georgescu, Maria-Magdalena\|Cote, Gilbert\|Agarwal, Nitin Kumar\|White, Charles L 3rd
PMID:	24862762

324.
Journal:	Cancer Biomark. 2014;14(2-3):177-84.
Title:	The prognostic value of the Na(+)/ H(+) exchanger regulatory factor 1 (NHERF1) protein in cancer.
Author:	Saponaro, Concetta\|Malfettone, Andrea\|Dell'Endice, Teresa Stefania\|Brunetti, Anna Elisabetta\|Achimas-Cadariu, Patriciu\|Paradiso, Angelo\|Mangia, Anita
PMID:	24878819

325.
Journal:	Oncotarget. 2014 May 30;5(10):2974-87.
Title:	MicroRNA-17-5p promotes chemotherapeutic drug resistance and tumour metastasis of colorectal cancer by repressing PTEN expression.
Author:	Fang, Lekun\|Li, Haoran\|Wang, Lei\|Hu, Jun\|Jin, Tianru\|Wang, Jianping\|Yang, Burton B
PMID:	24912422

326.
Journal:	Oncotarget. 2014 May 30;5(10):2999-3011.
Title:	WNT signaling and distant metastasis in colon cancer through transcriptional activity of nuclear beta-Catenin depend on active PI3K signaling.
Author:	Ormanns, Steffen\|Neumann, Jens\|Horst, David\|Kirchner, Thomas\|Jung, Andreas
PMID:	24930890

327.
Journal:	Tumour Biol. 2014 Sep;35(9):9233-40.
Title:	The association of phosphatase and tensin homolog deleted on chromosome 10 polymorphisms and lifestyle habits with colorectal cancer risk in a Chinese population.
Author:	Jing, Fangyuan\|Mao, Yingying\|Zhang, Zhenyu\|Li, Yingjun\|Cai, Shaofang\|Li, Qilong\|Ma, Xinyuan\|Jin, Mingjuan\|Chen, Kun
PMID:	24935469

328.
Journal:	Int J Mol Epidemiol Genet. 2014 May 29;5(2):100-11. eCollection 2014.
Title:	Influence of CHIEF pathway genes on gene expression: a pathway approach to functionality.
Author:	Slattery, Martha L\|Lundgreen, Abbie\|Mullany, Lila E\|Penney, Rosalind B\|Wolff, Roger K
PMID:	24959314

329.
Journal:	Biomed Res Int. 2014;2014:591867.
Title:	Current approaches for predicting a lack of response to anti-EGFR therapy in KRAS wild-type patients.
Author:	Er, Tze-Kiong\|Chen, Chih-Chieh\|Bujanda, Luis\|Herreros-Villanueva, Marta
PMID:	25032217

330.
Journal:	Genes Cancer. 2014 Mar;5(3-4):113-26.
Title:	Amphiregulin and PTEN evoke a multimodal mechanism of acquired resistance to PI3K inhibition.
Author:	Edgar, Kyle A\|Crocker, Lisa\|Cheng, Eric\|Wagle, Marie-Claire\|Wongchenko, Matthew\|Yan, Yibing\|Wilson, Timothy R\|Dompe, Nicholas\|Neve, Richard M\|Belvin, Marcia\|Sampath, Deepak\|Friedman, Lori S\|Wallin, Jeffrey J
PMID:	25053989

331.
Journal:	CMAJ Open. 2014 Feb 4;2(1):E11-7.
Title:	Utilization and costs of home care for patients with colorectal cancer: a population-based study.
Author:	Mittmann, Nicole\|Liu, Ning\|Porter, Joan\|Seung, Soo Jin\|Isogai, Pierre K\|Saskin, Refik\|Cheung, Matthew C\|Leighl, Natasha B\|Hoch, Jeffrey S\|Trudeau, Maureen\|Evans, William K\|Dainty, Katie N\|Earle, Craig C
PMID:	25077120

332.
Journal:	Biomed Pharmacother. 2014 Jul;68(6):721-7.
Title:	The PI3K/Akt pathway in colitis associated colon cancer and its chemoprevention with celecoxib, a Cox-2 selective inhibitor.
Author:	Setia, Shruti\|Nehru, Bimla\|Sanyal, Sankar Nath
PMID:	25107843

333.
Journal:	World J Gastroenterol. 2014 Aug 7;20(29):9732-43.
Title:	Beyond KRAS: Predictive factors of the efficacy of anti-EGFR monoclonal antibodies in the treatment of metastatic colorectal cancer.
Author:	De Stefano, Alfonso\|Carlomagno, Chiara
PMID:	25110411

334.
Journal:	Oncol Nurs Forum. 2014 Sep;41(5):555-7.
Title:	Cowden syndrome: what oncology nurses need to know about increased risk of developing certain cancers.
Author:	Beamer, Laura Curr
PMID:	25158662

335.
Journal:	Cancer Prev Res (Phila). 2014 Nov;7(11):1138-48.
Title:	Omega-3 fatty acid is a potential preventive agent for recurrent colon cancer.
Author:	Vasudevan, Anita\|Yu, Yingjie\|Banerjee, Sanjeev\|Woods, James\|Farhana, Lulu\|Rajendra, Sindhu G\|Patel, Aamil\|Dyson, Gregory\|Levi, Edi\|Maddipati, Krishna Rao\|Majumdar, Adhip P N\|Nangia-Makker, Pratima
PMID:	25193342

336.
Journal:	Oncol Lett. 2014 Oct;8(4):1543-1550.
Title:	Concomitant depletion of PTEN and p27 and overexpression of cyclin D1 may predict a worse prognosis for patients with post-operative stage II and III colorectal cancer.
Author:	Li, Jing\|Yin, Lin-Lin\|Su, Ke-Li\|Zhang, Gang-Feng\|Wang, Jing
PMID:	25202365

337.
Journal:	Int J Oncol. 2014 Dec;45(6):2486-94.
Title:	miR494 is an independent prognostic factor and promotes cell migration and invasion in colorectal cancer by directly targeting PTEN.
Author:	Sun, Hai-Bing\|Chen, Xi\|Ji, Hong\|Wu, Tao\|Lu, Hong-Wei\|Zhang, Yan\|Li, Hua\|Li, Yi-Ming
PMID:	25270723

338.
Journal:	J Environ Pathol Toxicol Oncol. 2014;33(3):233-7.
Title:	Silence of PTEN in colorectal cancer cells via siRNA inhibits cell growth.
Author:	Chen, Zhan-xin\|Sang, Qiu-tang\|Du, Yu-ga\|Xin, Yian-yan
PMID:	25272061

339.
Journal:	Genes Dev. 2014 Dec 1;28(23):2585-90.
Title:	Tumor suppression by miR-26 overrides potential oncogenic activity in intestinal tumorigenesis.
Author:	Zeitels, Lauren R\|Acharya, Asha\|Shi, Guanglu\|Chivukula, Divya\|Chivukula, Raghu R\|Anandam, Joselin L\|Abdelnaby, Abier A\|Balch, Glen C\|Mansour, John C\|Yopp, Adam C\|Richardson, James A\|Mendell, Joshua T
PMID:	25395662

340.
Journal:	Int Surg. 2014 Nov-Dec;99(6):795-801.
Title:	Conversion Therapy Using mFOLFOX6 With Panitumumab for Unresectable Liver Metastases From Multiple Colorectal Cancers With Familial Adenomatous Polyposis.
Author:	Toiyama, Yuji\|Inoue, Yasuhiro\|Kitajima, Takahito\|Okigami, Masato\|Kawamura, Mikio\|Kawamoto, Aya\|Okugawa, Yoshinaga\|Hiro, Jyunichiro\|Tanaka, Koji\|Mohri, Yasuhiko\|Kusunoki, Masato
PMID:	25437589

341.
Journal:	Biomed Pharmacother. 2014 Oct;68(8):1023-9.
Title:	Upregulation of MAPK/Erk and PI3K/Akt pathways in ulcerative colitis-associated colon cancer.
Author:	Setia, Shruti\|Nehru, Bimla\|Sanyal, Sankar Nath
PMID:	25443414

342.
Journal:	MAbs. 2014;6(6):1571-84.
Title:	CEA/CD3 bispecific antibody MEDI-565/AMG 211 activation of T cells and subsequent killing of human tumors is independent of mutations commonly found in colorectal adenocarcinomas.
Author:	Oberst, Michael D\|Fuhrmann, Stacy\|Mulgrew, Kathy\|Amann, Maria\|Cheng, Lily\|Lutterbuese, Petra\|Richman, Laura\|Coats, Steve\|Baeuerle, Patrick A\|Hammond, Scott A
PMID:	25484061

343.
Journal:	Int J Biol Markers. 2015 Feb 24;30(1):e73-80.
Title:	An exploratory biomarker study in metastatic tumors from colorectal cancer patients treated with bevacizumab.
Author:	Sclafani, Francesco\|Rimassa, Lorenza\|Colombo, Piergiuseppe\|Destro, Annarita\|Stinco, Sergio\|Lutman, Fabio R\|Carnaghi, Carlo\|Beretta, Giordano\|Zanello, Alessandro\|Roncalli, Massimo\|Giordano, Laura\|Santoro, Armando
PMID:	24980447

344.
Journal:	Gynecol Oncol. 2015 Jan;136(1):3-7.
Title:	Society of Gynecologic Oncology statement on risk assessment for inherited gynecologic cancer predispositions.
Author:	Lancaster, Johnathan M\|Powell, C Bethan\|Chen, Lee-May\|Richardson, Debra L
PMID:	25238946

345.
Journal:	Clin Transl Oncol. 2015 Apr;17(4):306-13.
Title:	Overexpression of ribonuclease inhibitor defines good prognosis and suppresses proliferation and metastasis in human colorectal cancer cells via PI3K/AKT pathway.
Author:	Tang, Y\|Liu, P\|Tian, Y\|Xu, Y\|Ren, F\|Cui, X\|Fan, J
PMID:	25257839

346.
Journal:	Clin Transl Oncol. 2015 Apr;17(4):264-73.
Title:	Updated guidelines for biomarker testing in colorectal carcinoma: a national consensus of the Spanish Society of Pathology and the Spanish Society of Medical Oncology.
Author:	Garcia-Alfonso, P\|Garcia-Foncillas, J\|Salazar, R\|Perez-Segura, P\|Garcia-Carbonero, R\|Musulen-Palet, E\|Cuatrecasas, M\|Landolfi, S\|Ramon Y Cajal, S\|Navarro, S
PMID:	25373533

347.
Journal:	Int J Cancer. 2015 Jun 15;136(12):2961-6.
Title:	Suppression of homologous recombination sensitizes human tumor cells to IGF-1R inhibition.
Author:	Lodhia, Kunal A\|Gao, Shan\|Aleksic, Tamara\|Esashi, Fumiko\|Macaulay, Valentine M
PMID:	25388513

348.
Journal:	Biochim Biophys Acta. 2015 Jan;1855(1):104-21.
Title:	Portrait of the PI3K/AKT pathway in colorectal cancer.
Author:	Danielsen, Stine Aske\|Eide, Peter Wold\|Nesbakken, Arild\|Guren, Tormod\|Leithe, Edward\|Lothe, Ragnhild A
PMID:	25450577

349.
Journal:	Ann Surg Oncol. 2015 Aug;22(8):2649-55.
Title:	MiR-92a Promotes Cell Metastasis of Colorectal Cancer Through PTEN-Mediated PI3K/AKT Pathway.
Author:	Ke, Tao-Wei\|Wei, Po-Li\|Yeh, Ken-Tu\|Chen, William Tzu-Liang\|Cheng, Ya-Wen
PMID:	25515201

350.
Journal:	Arch Med Res. 2015 Jan;46(1):17-23.
Title:	Catechol-O-methyltransferase inhibits colorectal cancer cell proliferation and invasion.
Author:	Wu, Wenming\|Wu, Qiao\|Hong, Xiafei\|Xiong, Guangbing\|Xiao, Yi\|Zhou, Jiaolin\|Wang, Wenze\|Wu, Huanwen\|Zhou, Li\|Song, Wei\|Dai, Hongmei\|Qiu, Huizhong\|Zhao, Yupei
PMID:	25532943

351.
Journal:	Genes Dev. 2015 Jan 15;29(2):157-70.
Title:	Poly-ADP ribosylation of PTEN by tankyrases promotes PTEN degradation and tumor growth.
Author:	Li, Nan\|Zhang, Yajie\|Han, Xin\|Liang, Ke\|Wang, Jiadong\|Feng, Lin\|Wang, Wenqi\|Songyang, Zhou\|Lin, Chunru\|Yang, Liuqing\|Yu, Yonghao\|Chen, Junjie
PMID:	25547115

352.
Journal:	Oncotarget. 2015 Feb 20;6(5):2939-50.
Title:	Cathelicidin, an antimicrobial peptide produced by macrophages, promotes colon cancer by activating the Wnt/beta-catenin pathway.
Author:	Li, Dong\|Liu, Wenfang\|Wang, Xuan\|Wu, Junlu\|Quan, Wenqiang\|Yao, Yiwen\|Bals, Robert\|Ji, Shurong\|Wu, Kaiyin\|Guo, Jia\|Wan, Haiying
PMID:	25596747

353.
Journal:	J Physiol Biochem. 2015 Mar;71(1):59-68.
Title:	MicroRNA-21 controls hTERT via PTEN in human colorectal cancer cell proliferation.
Author:	Yang, Yang\|Yang, Jing-Jing\|Tao, Hui\|Jin, Wei-Sen
PMID:	25603978

354.
Journal:	PLoS One. 2015 Jan 24;10(1):e0116753.
Title:	A pathway-centric survey of somatic mutations in Chinese patients with colorectal carcinomas.
Author:	Ling, Chao\|Wang, Lin\|Wang, Zheng\|Xu, Luming\|Sun, Lifang\|Yang, Hui\|Li, Wei-Dong\|Wang, Kai
PMID:	25617745

355.
Journal:	Integr Biol (Camb). 2015 Mar;7(3):324-34.
Title:	PTEN deletion potentiates invasion of colorectal cancer spheroidal cells through 3D Matrigel.
Author:	Chandrasekaran, Siddarth\|Deng, Huanyun\|Fang, Ye
PMID:	25625883

356.
Journal:	Tumour Biol. 2015 Jun;36(6):4833-42.
Title:	Non-enzymatic action of RRM1 protein upregulates PTEN leading to inhibition of colorectal cancer metastasis.
Author:	Qi, Hongyan\|Lou, Meng\|Chen, Yuexia\|Liu, Xiyong\|Chen, Naiming\|Shan, Jianzhen\|Ling, Zhiqiang\|Shen, Jing\|Zhu, Lijun\|Yen, Yun\|Zheng, Shu\|Shao, Jimin
PMID:	25638032

357.
Journal:	Sci Rep. 2015 Feb 2;5:8065.
Title:	Concordant analysis of KRAS, BRAF, PIK3CA mutations, and PTEN expression between primary colorectal cancer and matched metastases.
Author:	Mao, Chen\|Wu, Xin-Yin\|Yang, Zu-Yao\|Threapleton, Diane Erin\|Yuan, Jin-Qiu\|Yu, Yuan-Yuan\|Tang, Jin-Ling
PMID:	25639985

358.
Journal:	Mol Cell Biochem. 2015 Apr;402(1-2):225-41.
Title:	Downregulation of PI3-K/Akt/PTEN pathway and activation of mitochondrial intrinsic apoptosis by Diclofenac and Curcumin in colon cancer.
Author:	Rana, Chandan\|Piplani, Honit\|Vaish, Vivek\|Nehru, Bimla\|Sanyal, S N
PMID:	25644785

359.
Journal:	Tumour Biol. 2015 Jun;36(6):4747-55.
Title:	MiR-32 induces cell proliferation, migration, and invasion in hepatocellular carcinoma by targeting PTEN.
Author:	Yan, Shi-Yan\|Chen, Mei-Mei\|Li, Guang-Ming\|Wang, Yu-Qin\|Fan, Jian-Gao
PMID:	25647261

360.
Journal:	Oncol Rep. 2015 Apr;33(4):1828-36.
Title:	Effects of PTEN on the proliferation and apoptosis of colorectal cancer cells via the phosphoinositol-3-kinase/Akt pathway.
Author:	Sun, Yan\|Tian, Hua\|Wang, Lin
PMID:	25683168

361.
Journal:	Hum Pathol. 2015 Apr;46(4):507-13.
Title:	Novel molecular insights from routine genotyping of colorectal carcinomas.
Author:	Stachler, Matthew D\|Rinehart, Elizabeth\|Lindeman, Neal\|Odze, Robert\|Srivastava, Amitabh
PMID:	25683705

362.
Journal:	Cell Cycle. 2015;14(8):1252-9.
Title:	Cyclin-dependent kinase pathway aberrations in diverse malignancies: clinical and molecular characteristics.
Author:	Kato, Shumei\|Schwaederle, Maria\|Daniels, Gregory A\|Piccioni, David\|Kesari, Santosh\|Bazhenova, Lyudmila\|Shimabukuro, Kelly\|Parker, Barbara A\|Fanta, Paul\|Kurzrock, Razelle
PMID:	25695927

363.
Journal:	Cancer Res. 2015 Apr 15;75(8):1560-6.
Title:	Evaluating patient-derived colorectal cancer xenografts as preclinical models by comparison with patient clinical data.
Author:	Nunes, Manoel\|Vrignaud, Patricia\|Vacher, Sophie\|Richon, Sophie\|Lievre, Astrid\|Cacheux, Wulfran\|Weiswald, Louis-Bastien\|Massonnet, Gerald\|Chateau-Joubert, Sophie\|Nicolas, Andre\|Dib, Colette\|Zhang, Weidong\|Watters, James\|Bergstrom, Donald\|Roman-Roman, Sergi
PMID:	25712343

364.
Journal:	Mol Cancer Res. 2015 Jun;13(6):1003-8.
Title:	AKT1 E17K in Colorectal Carcinoma Is Associated with BRAF V600E but Not MSI-H Status: A Clinicopathologic Comparison to PIK3CA Helical and Kinase Domain Mutants.
Author:	Hechtman, Jaclyn F\|Sadowska, Justyna\|Huse, Jason T\|Borsu, Laetitia\|Yaeger, Rona\|Shia, Jinru\|Vakiani, Efsevia\|Ladanyi, Marc\|Arcila, Maria E
PMID:	25714871

365.
Journal:	J Cell Biochem. 2015 Sep;116(9):1837-47.
Title:	Oncogenic and Therapeutic Targeting of PTEN Loss in Bone Malignancies.
Author:	Xi, Yongming\|Chen, Yan
PMID:	25773992

366.
Journal:	Am J Surg Pathol. 2015 Aug;39(8):1140-7.
Title:	Distinctive Spatiotemporal Stability of Somatic Mutations in Metastasized Microsatellite-stable Colorectal Cancer.
Author:	Jesinghaus, Moritz\|Wolf, Thomas\|Pfarr, Nicole\|Muckenhuber, Alexander\|Ahadova, Aysel\|Warth, Arne\|Goeppert, Benjamin\|Sers, Christine\|Kloor, Matthias\|Endris, Volker\|Stenzinger, Albrecht\|Weichert, Wilko
PMID:	25786087

367.
Journal:	Rom J Morphol Embryol. 2015;56(1):175-81.
Title:	Histochemical and immunohistochemical evidence of tumor heterogeneity in colorectal cancer.
Author:	Zlatian, Ovidiu Mircea\|Comanescu, Maria Victoria\|Rosu, Alexandra Floriana\|Rosu, Lucica\|Cruce, Mihai\|Gaman, Alice Elena\|Calina, Cornelia Daniela\|Sfredel, Veronica
PMID:	25826503

368.
Journal:	World J Gastrointest Surg. 2015 Mar 27;7(3):25-32.
Title:	Colorectal cancer risk in hamartomatous polyposis syndromes.
Author:	Campos, Fabio Guilherme\|Figueiredo, Marleny Novaes\|Martinez, Carlos Augusto Real
PMID:	25848489

369.
Journal:	J Biol Chem. 2015 Jun 12;290(24):15018-29.
Title:	Phosphatase and Tensin Homolog (PTEN) Represses Colon Cancer Progression through Inhibiting Paxillin Transcription via PI3K/AKT/NF-kappaB Pathway.
Author:	Zhang, Ling-Li\|Mu, Gang-Gang\|Ding, Qian-Shan\|Li, Yan-Xia\|Shi, Yun-bo\|Dai, Jin-Fen\|Yu, Hong-Gang
PMID:	25873394

370.
Journal:	J Hematol Oncol. 2015 Mar 15;8:26.
Title:	Aloperine executes antitumor effects against multiple myeloma through dual apoptotic mechanisms.
Author:	Wang, He\|Yang, Shu\|Zhou, Hong\|Sun, Mingna\|Du, Lingran\|Wei, Minyan\|Luo, Meixia\|Huang, Jingzhu\|Deng, Hongzhu\|Feng, Yinghong\|Huang, Jun\|Zhou, Yi
PMID:	25886453

371.
Journal:	J Surg Oncol. 2015 Jun;111(7):905-10.
Title:	Mutations in the RAS and PI3K pathways are associated with metastatic location in colorectal cancers.
Author:	Lan, Yuan-Tzu\|Jen-Kou, Lin\|Lin, Chien-Hsing\|Yang, Shung-Haur\|Lin, Chun-Chi\|Wang, Huann-Sheng\|Chen, Wei-Shone\|Lin, Tzu-Chen\|Jiang, Jeng-Kai\|Chang, Shih-Ching
PMID:	25920435

372.
Journal:	Am J Cancer Res. 2015 Jan 15;5(2):674-88. eCollection 2015.
Title:	A specific KRAS codon 13 mutation is an independent predictor for colorectal cancer metachronous distant metastases.
Author:	Feng, Qingyang\|Liang, Li\|Ren, Li\|Chen, Jingwen\|Wei, Ye\|Chang, Wenju\|Zhu, Dexiang\|Lin, Qi\|Zheng, Peng\|Xu, Jianmin
PMID:	25973306

373.
Journal:	World J Surg Oncol. 2015 May 20;13:186.
Title:	A comprehensive analysis of phosphatase and tensin homolog deleted on chromosome 10 (PTEN) loss in colorectal cancer.
Author:	Lin, Pei-Ching\|Lin, Jen-Kou\|Lin, Hung-Hsin\|Lan, Yuan-Tzu\|Lin, Chun-Chi\|Yang, Shung-Haur\|Chen, Wei-Shone\|Liang, Wen-Yi\|Jiang, Jeng-Kai\|Chang, Shih-Ching
PMID:	25986931

374.
Journal:	Drug Resist Updat. 2015 May;20:39-70.
Title:	Pharmacogenomics of intrinsic and acquired pharmacoresistance in colorectal cancer: Toward targeted personalized therapy.
Author:	De Mattia, Elena\|Cecchin, Erika\|Toffoli, Giuseppe
PMID:	26027741

375.
Journal:	Am J Cancer Res. 2015 Feb 15;5(3):1047-61. eCollection 2015.
Title:	Hispidulin prevents hypoxia-induced epithelial-mesenchymal transition in human colon carcinoma cells.
Author:	Xie, Jing\|Gao, Hui\|Peng, Jianjun\|Han, Yantao\|Chen, Xuehong\|Jiang, Qixiao\|Wang, Chunbo
PMID:	26045985

376.
Journal:	Gastroenterology. 2015 Oct;149(4):981-92.e11.
Title:	MicroRNA214 Is Associated With Progression of Ulcerative Colitis, and Inhibition Reduces Development of Colitis and Colitis-Associated Cancer in Mice.
Author:	Polytarchou, Christos\|Hommes, Daniel W\|Palumbo, Tiziana\|Hatziapostolou, Maria\|Koutsioumpa, Marina\|Koukos, Georgios\|van der Meulen-de Jong, Andrea E\|Oikonomopoulos, Angelos\|van Deen, Welmoed K\|Vorvis, Christina\|Serebrennikova, Oksana B\|Birli, Eleni\|Choi, J
PMID:	26055138

377.
Journal:	Biomed Res Int. 2015;2015:823620.
Title:	MicroRNAs as Regulator of Signaling Networks in Metastatic Colon Cancer.
Author:	Wang, Jian\|Du, Yong\|Liu, Xiaoming\|Cho, William C\|Yang, Yinxue
PMID:	26064956

378.
Journal:	PLoS One. 2015 Jun 22;10(6):e0131108.
Title:	A Transition Zone Showing Highly Discontinuous or Alternating Levels of Stem Cell and Proliferation Markers Characterizes the Development of PTEN-Haploinsufficient Colorectal Cancer.
Author:	Arvai, Kevin J\|Hsu, Ya-Hsuan\|Lee, Lobin A\|Jones, Dan
PMID:	26098881

379.
Journal:	Mol Cancer Ther. 2015 Oct;14(10):2175-86.
Title:	Assessment of the In Vivo Activity of PI3K and MEK Inhibitors in Genetically Defined Models of Colorectal Cancer.
Author:	Raja, Meera\|Zverev, Matt\|Seipel, Katja\|Williams, Geraint T\|Clarke, Alan R\|Shaw, Paul H S
PMID:	26206338

380.
Journal:	Food Funct. 2015 Sep;6(9):3091-7.
Title:	Calycosin induces apoptosis by the regulation of ERbeta/miR-17 signaling pathway in human colorectal cancer cells.
Author:	Chen, Jian\|Zhao, Xinge\|Li, Xin\|Wu, Yiying
PMID:	26215320

381.
Journal:	Cancer Genet. 2015 Sep;208(9):441-7.
Title:	Diagnostic yield of targeted next generation sequencing in various cancer types: an information-theoretic approach.
Author:	Hagemann, Ian S\|O'Neill, Patrick K\|Erill, Ivan\|Pfeifer, John D
PMID:	26227479

382.
Journal:	Cancer Cell Int. 2015 Aug 1;15:77.
Title:	Antisense oligonucleotides against microRNA-21 reduced the proliferation and migration of human colon carcinoma cells.
Author:	Tao, Yi-Jing\|Li, Yong-Ju\|Zheng, Wen\|Zhao, Juan-Juan\|Guo, Meng-Meng\|Zhou, Ya\|Qin, Na-Lin\|Zheng, Jing\|Xu, Lin
PMID:	26236156

383.
Journal:	Pharmacogenomics. 2015;16(10):1189-222.
Title:	Molecular biomarkers in colorectal carcinoma.
Author:	Puerta-Garcia, Elena\|Canadas-Garre, Marisa\|Calleja-Hernandez, Miguel Angel
PMID:	26237292

384.
Journal:	J Transl Med. 2015 Aug 4;13:252.
Title:	MiR-106b induces cell radioresistance via the PTEN/PI3K/AKT pathways and p21 in colorectal cancer.
Author:	Zheng, Lin\|Zhang, Yuqin\|Liu, Yan\|Zhou, Min\|Lu, Yanxia\|Yuan, Li\|Zhang, Chao\|Hong, Min\|Wang, Shuang\|Li, Xuenong
PMID:	26238857

385.
Journal:	Int J Clin Exp Pathol. 2015 Jun 1;8(6):7112-21. eCollection 2015.
Title:	High expression of COUP-TF II cooperated with negative Smad4 expression predicts poor prognosis in patients with colorectal cancer.
Author:	Wang, Chaoqun\|Zhou, Yun\|Ruan, Ruoyun\|Zheng, Maojin\|Han, Wencan\|Liao, Linchuan
PMID:	26261604

386.
Journal:	Redox Biol. 2015 Dec;6:218-25.
Title:	Influence of myeloperoxidase on colon tumor occurrence in inflamed versus non-inflamed colons of Apc(Min/+) mice.
Author:	Al-Salihi, Mazin\|Reichert, Ethan\|Fitzpatrick, F A
PMID:	26262998

387.
Journal:	Clin Cancer Res. 2015 Dec 15;21(24):5499-5510.
Title:	MEK plus PI3K/mTORC1/2 Therapeutic Efficacy Is Impacted by TP53 Mutation in Preclinical Models of Colorectal Cancer.
Author:	Garcia-Garcia, Celina\|Rivas, Martin A\|Ibrahim, Yasir H\|Calvo, Maria Teresa\|Gris-Oliver, Albert\|Rodriguez, Olga\|Grueso, Judit\|Anton, Pilar\|Guzman, Marta\|Aura, Claudia\|Nuciforo, Paolo\|Jessen, Katti\|Argiles, Guillem\|Dienstmann, Rodrigo\|Bertotti, Andrea\|Truso
PMID:	26272063

388.
Journal:	J Clin Oncol. 2015 Dec 1;33(34):4023-31.
Title:	Combined BRAF and MEK Inhibition With Dabrafenib and Trametinib in BRAF V600-Mutant Colorectal Cancer.
Author:	Corcoran, Ryan B\|Atreya, Chloe E\|Falchook, Gerald S\|Kwak, Eunice L\|Ryan, David P\|Bendell, Johanna C\|Hamid, Omid\|Messersmith, Wells A\|Daud, Adil\|Kurzrock, Razelle\|Pierobon, Mariaelena\|Sun, Peng\|Cunningham, Elizabeth\|Little, Shonda\|Orford, Keith\|Motwani, Mo
PMID:	26392102

389.
Journal:	Cell Res. 2015 Nov;25(11):1189-204.
Title:	PTEN regulates RPA1 and protects DNA replication forks.
Author:	Wang, Guangxi\|Li, Yang\|Wang, Pan\|Liang, Hui\|Cui, Ming\|Zhu, Minglu\|Guo, Limei\|Su, Qian\|Sun, Yujie\|McNutt, Michael A\|Yin, Yuxin
PMID:	26403191

390.
Journal:	Oncotarget. 2015 Nov 17;6(36):38667-80.
Title:	Hes1 promotes cell proliferation and migration by activating Bmi-1 and PTEN/Akt/GSK3beta pathway in human colon cancer.
Author:	Gao, Fei\|Huang, Wei\|Zhang, YuQin\|Tang, ShaoHui\|Zheng, Lin\|Ma, Feng\|Wang, YiMing\|Tang, Hui\|Li, Xin
PMID:	26452029

391.
Journal:	PLoS One. 2015 Oct 15;10(10):e0140479.
Title:	Targeting AKT1-E17K and the PI3K/AKT Pathway with an Allosteric AKT Inhibitor, ARQ 092.
Author:	Yu, Yi\|Savage, Ronald E\|Eathiraj, Sudharshan\|Meade, Justin\|Wick, Michael J\|Hall, Terence\|Abbadessa, Giovanni\|Schwartz, Brian
PMID:	26469692

392.
Journal:	PLoS One. 2015 Oct 22;10(10):e0141020.
Title:	Loss of PTEN Facilitates Rosiglitazone-Mediated Enhancement of Platinum(IV) Complex LA-12-Induced Apoptosis in Colon Cancer Cells.
Author:	Laukova, Jarmila\|Kozubik, Alois\|Hofmanova, Jirina\|Nekvindova, Jana\|Sova, Petr\|Moyer, Mary Pat\|Ehrmann, Jiri\|Hyrslova Vaculova, Alena
PMID:	26492315

393.
Journal:	Genes Nutr. 2015 Nov;10(6):49.
Title:	Metformin and soybean-derived bioactive molecules attenuate the expansion of stem cell-like epithelial subpopulation and confer apoptotic sensitivity in human colon cancer cells.
Author:	Montales, Maria Theresa E\|Simmen, Rosalia C M\|Ferreira, Ederlan S\|Neves, Valdir A\|Simmen, Frank A
PMID:	26506839

394.
Journal:	BMC Cancer. 2015 Oct 27;15:808.
Title:	Prediction of response to anti-EGFR antibody-based therapies by multigene sequencing in colorectal cancer patients.
Author:	Lupini, Laura\|Bassi, Cristian\|Mlcochova, Jitka\|Musa, Gentian\|Russo, Marta\|Vychytilova-Faltejskova, Petra\|Svoboda, Marek\|Sabbioni, Silvia\|Nemecek, Radim\|Slaby, Ondrej\|Negrini, Massimo
PMID:	26508446

395.
Journal:	Oncotarget. 2015 Dec 8;6(39):42334-44.
Title:	Mutational profiling of colorectal cancers with microsatellite instability.
Author:	Lin, Elaine I\|Tseng, Li-Hui\|Gocke, Christopher D\|Reil, Stacy\|Le, Dung T\|Azad, Nilofer S\|Eshleman, James R
PMID:	26517354

396.
Journal:	PLoS Genet. 2015 Nov 3;11(11):e1005638.
Title:	Tissue-Specific Effects of Reduced beta-catenin Expression on Adenomatous Polyposis Coli Mutation-Instigated Tumorigenesis in Mouse Colon and Ovarian Epithelium.
Author:	Feng, Ying\|Sakamoto, Naoya\|Wu, Rong\|Liu, Jie-Yu\|Wiese, Alexandra\|Green, Maranne E\|Green, Megan\|Akyol, Aytekin\|Roy, Badal C\|Zhai, Yali\|Cho, Kathleen R\|Fearon, Eric R
PMID:	26528816

397.
Journal:	Int J Clin Exp Pathol. 2015 Oct 1;8(10):13314-22. eCollection 2015.
Title:	Roles of genetic variants in the PI3K/PTEN pathways in susceptibility to colorectal carcinoma and clinical outcomes treated with FOLFOX regimen.
Author:	Lin, Lin\|Zhang, Zhaoxu\|Zhang, Wen\|Wang, Lin\|Wang, Jinwan
PMID:	26722535

398.
Journal:	Rom J Morphol Embryol. 2015;56(4):1389-96.
Title:	Changes in immunoexpression of p53, Ki-67, Ets-1, APAF-1 and PTEN in serrated and conventional colon adenomas.
Author:	Pap, Zsuzsanna\|Ilyes, Izabella Agota\|Mocan, Simona Liliana\|Denes, Lorand\|Muica Nagy-Bota, Monica Cristina\|Pavai, Zoltan\|Szanto, Annamaria
PMID:	26743285

399.
Journal:	Gastroenterol Res Pract. 2015;2015:457193.
Title:	Bufalin Inhibits HCT116 Colon Cancer Cells and Its Orthotopic Xenograft Tumor in Mice Model through Genes Related to Apoptotic and PTEN/AKT Pathways.
Author:	Wang, Jie\|Chen, Chao\|Wang, Shiying\|Zhang, Yong\|Yin, Peihao\|Gao, Zhongxiang\|Xu, Jie\|Feng, Dianxu\|Zuo, Qinsong\|Zhao, Ronghua\|Chen, Teng
PMID:	26770191

400.
Journal:	CMAJ Open. 2015 Oct 29;3(4):E373-81.
Title:	Small-area variation in screening for cancer, glucose and cholesterol in Ontario: a cross-sectional study.
Author:	Fernandes, Kimberly A\|Sutradhar, Rinku\|Borkhoff, Cornelia M\|Baxter, Nancy\|Lofters, Aisha\|Rabeneck, Linda\|Tinmouth, Jill\|Paszat, Lawrence
PMID:	26835437

401.
Journal:	Int J Clin Exp Med. 2015 Nov 15;8(11):21629-34. eCollection 2015.
Title:	Association of genetic polymorphisms in PTEN and additional interaction with alcohol consumption and smoking on colorectal cancer in Chinese population.
Author:	Han, Mingyang\|Wu, Gang\|Sun, Peichun\|Nie, Jiewei\|Zhang, Jiancheng\|Li, Yuanyuan
PMID:	26885116

402.
Journal:	J Cell Biochem. 2016 Feb;117(2):458-69.
Title:	PTEN Overexpression Cooperates With Lithium to Reduce the Malignancy and to Increase Cell Death by Apoptosis via PI3K/Akt Suppression in Colorectal Cancer Cells.
Author:	de Araujo, Wallace Martins\|Robbs, Bruno Kaufmann\|Bastos, Lilian G\|de Souza, Waldemir F\|Vidal, Flavia C B\|Viola, Joao P B\|Morgado-Diaz, Jose A
PMID:	26224641

403.
Journal:	J Clin Pathol. 2016 Jan;69(1):35-41.
Title:	Pre-trial inter-laboratory analytical validation of the FOCUS4 personalised therapy trial.
Author:	Richman, Susan D\|Adams, Richard\|Quirke, Phil\|Butler, Rachel\|Hemmings, Gemma\|Chambers, Phil\|Roberts, Helen\|James, Michelle D\|Wozniak, Sue\|Bathia, Riya\|Pugh, Cheryl\|Maughan, Timothy\|Jasani, Bharat
PMID:	26350752

404.
Journal:	Ann Surg Oncol. 2016 Mar;23(3):849-55.
Title:	Mutation Spectra of Common Cancer-Associated Genes in Different Phenotypes of Colorectal Carcinoma Without Distant Metastasis.
Author:	Chang, Shih-Ching\|Lin, Pei-Ching\|Lin, Jen-Kou\|Lin, Chien-Hsing\|Yang, Shung-Haur\|Liang, Wen-Yi\|Chen, Wei-Shone\|Jiang, Jeng-Kai
PMID:	26471487

405.
Journal:	Cancer Med. 2016 Feb;5(2):256-64.
Title:	KRAS mutation in lung metastases from colorectal cancer: prognostic implications.
Author:	Ghidini, Michele\|Personeni, Nicola\|Bozzarelli, Silvia\|Baretti, Marina\|Basso, Gianluca\|Bianchi, Paolo\|Tronconi, Maria Chiara\|Pressiani, Tiziana\|Grizzi, Fabio\|Giordano, Laura\|Malesci, Alberto\|Alloisio, Marco\|Laghi, Luigi\|Santoro, Armando\|Rimassa, Lorenza
PMID:	26715198

406.
Journal:	Oncol Rep. 2016 Mar;35(3):1403-8.
Title:	Expression and mechanism of microRNA-181A on incidence and survival in late liver metastases of colorectal cancer.
Author:	Li, Zengjun\|Wang, Haipeng\|Xu, Zhongfa\|Sun, Yanlai\|Han, Jianjun
PMID:	26750720

407.
Journal:	J Biomed Sci. 2016 Jan 19;23:9.
Title:	The prognostic effect of PTEN expression status in colorectal cancer development and evaluation of factors affecting it: miR-21 and promoter methylation.
Author:	Yazdani, Yaghoub\|Farazmandfar, Touraj\|Azadeh, Hossein\|Zekavatian, Zeinab
PMID:	26787105

408.
Journal:	J Clin Pathol. 2016 Sep;69(9):767-71.
Title:	Less frequently mutated genes in colorectal cancer: evidences from next-generation sequencing of 653 routine cases.
Author:	Malapelle, Umberto\|Pisapia, Pasquale\|Sgariglia, Roberta\|Vigliar, Elena\|Biglietto, Maria\|Carlomagno, Chiara\|Giuffre, Giuseppe\|Bellevicine, Claudio\|Troncone, Giancarlo
PMID:	26797410

409.
Journal:	Onco Targets Ther. 2016 Jan 27;9:557-65.
Title:	Biomarkers predicting resistance to epidermal growth factor receptor-targeted therapy in metastatic colorectal cancer with wild-type KRAS.
Author:	Liu, Jiang\|Hu, Jing\|Cheng, Lei\|Ren, Wei\|Yang, Mi\|Liu, Baorui\|Xie, Li\|Qian, Xiaoping
PMID:	26869800

410.
Journal:	Oncotarget. 2016 Apr 12;7(15):19610-9.
Title:	Molecular characterization of colorectal cancer patients and concomitant patient-derived tumor cell establishment.
Author:	Song, Haa-Na\|Lee, Chung\|Kim, Seung Tae\|Kim, Sun Young\|Kim, Nayoung K D\|Jang, Jiryeon\|Kang, Mihyun\|Jang, Hyojin\|Ahn, Soomin\|Kim, Seok Hyeong\|Park, Yoona\|Cho, Yong Beom\|Heo, Jeong Wook\|Lee, Woo Yong\|Park, Joon Oh\|Lim, Ho Yeong\|Kang, Won Ki\|Park, Young Suk\|P
PMID:	26909603

411.
Journal:	Neoplasma. 2016;63(3):351-61.
Title:	Physcion 8-O-beta-glucopyranoside prevents hypoxia-induced epithelial-mesenchymal transition in colorectal cancer HCT116 cells by modulating EMMPRIN.
Author:	Ding, Z\|Xu, F\|Tang, J\|Li, G\|Jiang, P\|Tang, Z\|Wu, H
PMID:	26925795

412.
Journal:	Mol Cancer Ther. 2016 Jun;15(6):1217-26.
Title:	Dual Targeting of Bromodomain and Extraterminal Domain Proteins, and WNT or MAPK Signaling, Inhibits c-MYC Expression and Proliferation of Colorectal Cancer Cells.
Author:	Togel, Lars\|Nightingale, Rebecca\|Chueh, Anderly C\|Jayachandran, Aparna\|Tran, Hoanh\|Phesse, Toby\|Wu, Rui\|Sieber, Oliver M\|Arango, Diego\|Dhillon, Amardeep S\|Dawson, Mark A\|Diez-Dacal, Beatriz\|Gahman, Timothy C\|Filippakopoulos, Panagis\|Shiau, Andrew K\|Mariad
PMID:	26983878

413.
Journal:	Oncotarget. 2016 Apr 19;7(16):22687-99.
Title:	DDX3 enhances oncogenic KRASinduced tumor invasion in colorectal cancer via the betacatenin/ZEB1 axis.
Author:	Wu, De-Wei\|Lin, Po-Lin\|Cheng, Ya-Wen\|Huang, Chi-Chou\|Wang, Lee\|Lee, Huei
PMID:	27007150

414.
Journal:	J Biol Regul Homeost Agents. 2016 Jan-Mar;30(1):79-90.
Title:	A novel quantitative method of pten expression assessment in tumor tissue.
Author:	Waniczek, D\|Snietura, M\|Kopec, A\|Scieglinska, D\|Piglowski, W\|Lorenc, Z\|Muc-Wierzgon, M\|Nowakowska-Zajdel, E
PMID:	27049078

415.
Journal:	Sci Rep. 2016 Apr 18;6:24671.
Title:	Establishment and characterization of HROC69 - a Crohn s related colonic carcinoma cell line and its matched patient-derived xenograft.
Author:	Kuehn, Florian\|Mullins, Christina S\|Krohn, Mathias\|Harnack, Christine\|Ramer, Robert\|Kramer, Oliver H\|Klar, Ernst\|Huehns, Maja\|Linnebacher, Michael
PMID:	27087592

416.
Journal:	Biomarkers. 2016 Apr 21:1-5.
Title:	Allelic loss at PTEN locus leads to progression of colorectal carcinoma among North Indian patients.
Author:	Ali, Asgar\|Mehdi, Syed Jafar\|Hajela, Krishnan\|Saluja, Sundeep Singh\|Mishra, Pramod Kumar\|Sameer, Aga Syed\|Rizvi, M Moshahid Alam
PMID:	27098297

417.
Journal:	Oncol Rep. 2016 Jun;35(6):3341-8.
Title:	Oridonin upregulates PTEN through activating p38 MAPK and inhibits proliferation in human colon cancer cells.
Author:	Wu, Qiu-Xiang\|Yuan, Shuang-Xue\|Ren, Chun-Mei\|Yu, Yu\|Sun, Wen-Juan\|He, Bai-Cheng\|Wu, Ke
PMID:	27108927

418.
Journal:	Oncotarget. 2016 Aug 2;7(31):49042-49064.
Title:	Vitamin D3 suppresses morphological evolution of the cribriform cancerous phenotype.
Author:	Deevi, Ravi K\|McClements, Jane\|McCloskey, Karen D\|Fatehullah, Aliya\|Tkocz, Dorota\|Javadi, Arman\|Higginson, Robyn\|Marsh Durban, Victoria\|Jansen, Marnix\|Clarke, Alan\|Loughrey, Maurice B\|Campbell, Frederick C
PMID:	27119498

419.
Journal:	J Transl Med. 2016 May 4;14(1):118.
Title:	Clinical significance of frequent somatic mutations detected by high-throughput targeted sequencing in archived colorectal cancer samples.
Author:	Dallol, Ashraf\|Buhmeida, Abdelbaset\|Al-Ahwal, Mahmoud Shaheen\|Al-Maghrabi, Jaudah\|Bajouh, Osama\|Al-Khayyat, Shadi\|Alam, Rania\|Abusanad, Atlal\|Turki, Rola\|Elaimi, Aisha\|Alhadrami, Hani A\|Abuzenadah, Mohammed\|Banni, Huda\|Al-Qahtani, Mohammed H\|Abuzenadah, A
PMID:	27146902

420.
Journal:	Hered Cancer Clin Pract. 2016 May 10;14:11.
Title:	An unusual case of Cowden syndrome associated with ganglioneuromatous polyposis.
Author:	Pistorius, Steffen\|Klink, Barbara\|Pablik, Jessica\|Rump, Andreas\|Aust, Daniela\|Garzarolli, Marlene\|Schrock, Evelin\|Schackert, Hans K
PMID:	27168869

421.
Journal:	Proc Natl Acad Sci U S A. 2016 Jun 7;113(23):E3250-9.
Title:	Growth hormone is permissive for neoplastic colon growth.
Author:	Chesnokova, Vera\|Zonis, Svetlana\|Zhou, Cuiqi\|Recouvreux, Maria Victoria\|Ben-Shlomo, Anat\|Araki, Takako\|Barrett, Robert\|Workman, Michael\|Wawrowsky, Kolja\|Ljubimov, Vladimir A\|Uhart, Magdalena\|Melmed, Shlomo
PMID:	27226307

422.
Journal:	Front Physiol. 2016 May 9;7:168.
Title:	The Inositide Signaling Pathway As a Target for Treating Gastric Cancer and Colorectal Cancer.
Author:	Kim, Hong Jun\|Lee, Suk-Young\|Oh, Sang Cheul
PMID:	27242542

423.
Journal:	Arch Biochem Biophys. 2016 Aug 15;604:20-6.
Title:	IL-1beta/NF-kb signaling promotes colorectal cancer cell growth through miR-181a/PTEN axis.
Author:	Hai Ping, Pei\|Feng Bo, Tan\|Li, Liu\|Nan Hui, Yu\|Hong, Zhu
PMID:	27264420

424.
Journal:	BMC Cancer. 2016 Jun 13;16:366.
Title:	PTEN mRNA expression is less pronounced in left- than right-sided colon cancer: a retrospective observational study.
Author:	Kuramochi, Hidekazu\|Nakamura, Ayako\|Nakajima, Go\|Kaneko, Yuka\|Araida, Tatsuo\|Yamamoto, Masakazu\|Hayashi, Kazuhiko
PMID:	27296289

425.
Journal:	Gastroenterology. 2016 Sep;151(3):440-447.e1.
Title:	Frequent PIK3CA Mutations in Colorectal and Endometrial Tumors With 2 or More Somatic Mutations in Mismatch Repair Genes.
Author:	Cohen, Stacey A\|Turner, Emily H\|Beightol, Mallory B\|Jacobson, Angela\|Gooley, Ted A\|Salipante, Stephen J\|Haraldsdottir, Sigurdis\|Smith, Christina\|Scroggins, Sheena\|Tait, Jonathan F\|Grady, William M\|Lin, Edward H\|Cohn, David E\|Goodfellow, Paul J\|Arnold, Mar
PMID:	27302833

426.
Journal:	World J Gastroenterol. 2016 Jun 28;22(24):5532-9.
Title:	MicroRNA-21 promotes phosphatase gene and protein kinase B/phosphatidylinositol 3-kinase expression in colorectal cancer.
Author:	Sheng, Wei-Zhong\|Chen, Yu-Sheng\|Tu, Chuan-Tao\|He, Juan\|Zhang, Bo\|Gao, Wei-Dong
PMID:	27350731

427.
Journal:	Biochim Biophys Acta. 2016 Aug;1866(1):106-20.
Title:	DNA methylation based biomarkers in colorectal cancer: A systematic review.
Author:	Lam, Kevin\|Pan, Kathy\|Linnekamp, Janneke Fiona\|Medema, Jan Paul\|Kandimalla, Raju
PMID:	27385266

428.
Journal:	Diagn Pathol. 2016 Jul 8;11(1):61.
Title:	In depth evaluation of the prognostic and predictive utility of PTEN immunohistochemistry in colorectal carcinomas: performance of three antibodies with emphasis on intracellular and intratumoral heterogeneity.
Author:	Agoston, Emese Irma\|Micsik, Tamas\|Acs, Balazs\|Fekete, Krisztina\|Hahn, Oszkar\|Baranyai, Zsolt\|Dede, Kristof\|Bodoky, Gyorgy\|Bursics, Attila\|Kulka, Janina\|Krenacs, Tibor\|Gyorffy, Balazs\|Harsanyi, Laszlo\|Szasz, A Marcell
PMID:	27392434

429.
Journal:	Oncol Rep. 2016 Sep;36(3):1457-66.
Title:	Crocodile blood extract induces the apoptosis of lung cancer cells through PTEN activity.
Author:	Ou, Yuqian\|Ho, Wing Shing
PMID:	27431918

430.
Journal:	Tumour Biol. 2016 Oct;37(10):13355-13368.
Title:	Neutral endopeptidase (NEP) is differentially involved in biological activities and cell signaling of colon cancer cell lines derived from various stages of tumor development.
Author:	Mizerska-Kowalska, Magdalena\|Bojarska-Junak, Agnieszka\|Jakubowicz-Gil, Joanna\|Kandefer-Szerszen, Martyna
PMID:	27460083

431.
Journal:	Cancer Med. 2016 Sep;5(9):2417-26.
Title:	Lentivirus-mediated shRNA interference of ghrelin receptor blocks proliferation in the colorectal cancer cells.
Author:	Liu, An\|Huang, Chenggang\|Xu, Jia\|Cai, Xuehong
PMID:	27464938

432.
Journal:	J Pathol Clin Res. 2016 Apr 15;2(3):166-74.
Title:	Somatic mutation profiles in primary colorectal cancers and matching ovarian metastases: Identification of driver and passenger mutations.
Author:	Crobach, Stijn\|Ruano, Dina\|van Eijk, Ronald\|Schrumpf, Melanie\|Fleuren, Gertjan\|van Wezel, Tom\|Morreau, Hans
PMID:	27499925

433.
Journal:	Carcinogenesis. 2016 Nov 1;37(11):1079-1088.
Title:	Downregulation of AIF by HIF-1 contributes to hypoxia-induced epithelial-mesenchymal transition of colon cancer.
Author:	Xiong, Zhong\|Guo, Meng\|Yu, Yun\|Zhang, Fei-Fei\|Ge, Meng-Kai\|Chen, Guo-Qiang\|Shen, Shao-Ming
PMID:	27543779

434.
Journal:	Radiat Res. 2016 Sep;186(3):292-301.
Title:	MiR-29a Regulates Radiosensitivity in Human Intestinal Cells by Targeting PTEN Gene.
Author:	Wang, Juan\|Xu, Jinping\|Fu, Jiamei\|Yuan, Dexiao\|Guo, Fei\|Zhou, Cuiping\|Shao, Chunlin
PMID:	27548517

435.
Journal:	Neoplasia. 2016 Aug;18(8):512-23.
Title:	NHERF1/EBP50 Suppresses Wnt-beta-Catenin Pathway-Driven Intestinal Neoplasia.
Author:	Georgescu, Maria-Magdalena\|Gagea, Mihai\|Cote, Gilbert
PMID:	27566107

436.
Journal:	Med Oncol. 2016 Oct;33(10):106.
Title:	Targeted molecular profiling of rare genetic alterations in colorectal cancer using next-generation sequencing.
Author:	Jauhri, Mayank\|Bhatnagar, Akanksha\|Gupta, Satish\|Shokeen, Yogender\|Minhas, Sachin\|Aggarwal, Shyam
PMID:	27568332

437.
Journal:	World J Gastroenterol. 2016 Aug 14;22(30):6944-54.
Title:	Prognostic and predictive biomarkers in metastatic colorectal cancer anti-EGFR therapy.
Author:	Lo Nigro, Cristiana\|Ricci, Vincenzo\|Vivenza, Daniela\|Granetto, Cristina\|Fabozzi, Teresa\|Miraglio, Emanuela\|Merlano, Marco C
PMID:	27570430

438.
Journal:	Oncoimmunology. 2016 Mar 28;5(7):e1164918.
Title:	Myeloid PTEN deficiency impairs tumor-immune surveillance via immune-checkpoint inhibition.
Author:	Kuttke, M\|Sahin, E\|Pisoni, J\|Percig, S\|Vogel, A\|Kraemmer, D\|Hanzl, L\|Brunner, J S\|Paar, H\|Soukup, K\|Halfmann, A\|Dohnal, A M\|Steiner, C W\|Bluml, S\|Basilio, J\|Hochreiter, B\|Salzmann, M\|Hoesel, B\|Lametschwandtner, G\|Eferl, R\|Schmid, J A\|Schabbauer, G
PMID:	27622019

439.
Journal:	PLoS One. 2016 Sep 14;11(9):e0162077.
Title:	Telomere Length, TERT, and miRNA Expression.
Author:	Slattery, Martha L\|Herrick, Jennifer S\|Pellatt, Andrew J\|Wolff, Roger K\|Mullany, Lila E
PMID:	27627813

440.
Journal:	Anticancer Res. 2016 Sep;36(9):4537-43.
Title:	MEK Inhibitor Suppresses Expression of the miR-17-92 Cluster with G1-Phase Arrest in HT-29 Human Colon Cancer Cells and MIA PaCa-2 Pancreatic Cancer Cells.
Author:	Tanaka, Ryoichi\|Tomosugi, Mitsuhiro\|Sakai, Toshiyuki\|Sowa, Yoshihiro
PMID:	27630293

441.
Journal:	Oncotarget. 2016 Oct 25;7(43):70601-70612.
Title:	Relationship between tumour PTEN/Akt/COX-2 expression, inflammatory response and survival in patients with colorectal cancer.
Author:	Roseweir, Antonia K\|Powell, Arfon G M T\|Bennett, Lindsay\|Van Wyk, Hester C\|Park, James\|McMillan, Donald C\|Horgan, Paul G\|Edwards, Joanne
PMID:	27661110

442.
Journal:	Oncotarget. 2016 Nov 8;7(45):72908-72922.
Title:	Genomic characterization of liver metastases from colorectal cancer patients.
Author:	Sayagues, Jose Maria\|Corchete, Luis Antonio\|Gutierrez, Maria Laura\|Sarasquete, Maria Eugenia\|Del Mar Abad, Maria\|Bengoechea, Oscar\|Ferminan, Encarna\|Anduaga, Maria Fernanda\|Del Carmen, Sofia\|Iglesias, Manuel\|Esteban, Carmen\|Angoso, Maria\|Alcazar, Jose Ant
PMID:	27662660

443.
Journal:	Oncologist. 2016 Nov;21(11):1306-1314.
Title:	Broad Detection of Alterations Predicted to Confer Lack of Benefit From EGFR Antibodies or Sensitivity to Targeted Therapy in Advanced Colorectal Cancer.
Author:	Rankin, Andrew\|Klempner, Samuel J\|Erlich, Rachel\|Sun, James X\|Grothey, Axel\|Fakih, Marwan\|George, Thomas J Jr\|Lee, Jeeyun\|Ross, Jeffrey S\|Stephens, Philip J\|Miller, Vincent A\|Ali, Siraj M\|Schrock, Alexa B
PMID:	27682134

444.
Journal:	Biomed Pharmacother. 2016 Dec;84:601-607.
Title:	Odontogenic ameloblast-associated protein (ODAM) inhibits human colorectal cancer growth by promoting PTEN elevation and inactivating PI3K/AKT signaling.
Author:	Yu, Minhao\|Mu, Yifei\|Qi, Yang\|Qin, Shaolan\|Qiu, Yier\|Cui, Ran\|Zhong, Ming
PMID:	27694004

445.
Journal:	Oncotarget. 2016 Nov 8;7(45):73525-73540.
Title:	Lipid phosphatase SHIP2 functions as oncogene in colorectal cancer by regulating PKB activation.
Author:	Hoekstra, Elmer\|Das, Asha M\|Willemsen, Marcella\|Swets, Marloes\|Kuppen, Peter J K\|van der Woude, Christien J\|Bruno, Marco J\|Shah, Jigisha P\|Ten Hagen, Timo L M\|Chisholm, John D\|Kerr, William G\|Peppelenbosch, Maikel P\|Fuhler, Gwenny M
PMID:	27716613

446.
Journal:	Mol Cancer. 2016 Oct 18;15(1):63.
Title:	Spatio-temporal mutation profiles of case-matched colorectal carcinomas and their metastases reveal unique de novo mutations in metachronous lung metastases by targeted next generation sequencing.
Author:	Kovaleva, Valentina\|Geissler, Anna-Lena\|Lutz, Lisa\|Fritsch, Ralph\|Makowiec, Frank\|Wiesemann, Sebastian\|Hopt, Ulrich T\|Passlick, Bernward\|Werner, Martin\|Lassmann, Silke
PMID:	27756406

447.
Journal:	BMC Bioinformatics. 2016 Oct 22;17(1):430.
Title:	Subcellular protein expression models for microsatellite instability in colorectal adenocarcinoma tissue images.
Author:	Kovacheva, Violeta N\|Rajpoot, Nasir M
PMID:	27770786

448.
Journal:	World J Clin Oncol. 2016 Oct 10;7(5):340-351.
Title:	Oncogenic fingerprint of epidermal growth factor receptor pathway and emerging epidermal growth factor receptor blockade resistance in colorectal cancer.
Author:	Sobani, Zain A\|Sawant, Ashwin\|Jafri, Mikram\|Correa, Amit Keith\|Sahin, Ibrahim Halil
PMID:	27777877

449.
Journal:	Nat Commun. 2016 Nov 29;7:13615.
Title:	Functional exploration of colorectal cancer genomes using Drosophila.
Author:	Bangi, Erdem\|Murgia, Claudio\|Teague, Alexander G S\|Sansom, Owen J\|Cagan, Ross L
PMID:	27897178

450.
Journal:	Exp Mol Pathol. 2016 Dec;101(3):308-313.
Title:	MiR-200a acts as an oncogene in colorectal carcinoma by targeting PTEN.
Author:	Li, Yijun\|Sun, Jinglu\|Cai, Yongping\|Jiang, Yan\|Wang, Xiaoqing\|Huang, Xiaojuan\|Yin, Yu\|Li, Hao
PMID:	27983967

451.
Journal:	Gan To Kagaku Ryoho. 2016 Nov;43(12):1800-1802.
Title:	[A Case of Metastatic Colon Cancer Dramatically Affected by Anti-EGFR Antibody Therapy].
Author:	Yagi, Ryoma\|Shimada, Yoshifumi\|Miura, Kohei\|Tajima, Yosuke\|Okamura, Takuma\|Nakano, Masato\|Ichikawa, Hiroshi\|Nagahashi, Masayuki\|Sakata, Jun\|Kobayashi, Takashi\|Kameyama, Hitoshi\|Wakai, Toshifumi\|Nogami, Hitoshi\|Maruyama, Satoshi\|Takii, Yasumasa
PMID:	28133136

452.
Journal:	Breast Cancer Res Treat. 2017 Aug;165(1):1-8.
Title:	Breast cancer risk and clinical implications for germline PTEN mutation carriers.
Author:	Ngeow, Joanne\|Sesock, Kaitlin\|Eng, Charis
PMID:	26700035

453.
Journal:	Mol Carcinog. 2017 Jan;56(1):250-257.
Title:	Dysregulation of MicroRNA-543 expression in colorectal cancer promotes tumor migration and invasion.
Author:	Sun, Jian\|Zhou, Jianping\|Dong, Ming\|Sheng, Weiwei
PMID:	27148794

454.
Journal:	Oncogene. 2017 Feb 2;36(5):687-699.
Title:	Interleukin-17 promotes prostate cancer via MMP7-induced epithelial-to-mesenchymal transition.
Author:	Zhang, Q\|Liu, S\|Parajuli, K R\|Zhang, W\|Zhang, K\|Mo, Z\|Liu, J\|Chen, Z\|Yang, S\|Wang, A R\|Myers, L\|You, Z
PMID:	27375020

455.
Journal:	J Clin Gastroenterol. 2017 Aug;51(7):e60-e67.
Title:	Gastrointestinal Polyposis in Cowden Syndrome.
Author:	Shaco-Levy, Ruthy\|Jasperson, Kory W\|Martin, Katie\|Samadder, N J\|Burt, Randall W\|Ying, Jian\|Bronner, Mary P
PMID:	27661969

456.
Journal:	Oncotarget. 2017 Mar 21;8(12):18832-18847.
Title:	Selenite inhibits glutamine metabolism and induces apoptosis by regulating GLS1 protein degradation via APC/C-CDH1 pathway in colorectal cancer cells.
Author:	Zhao, Junzhang\|Zhou, Rui\|Hui, Kaiyuan\|Yang, Yang\|Zhang, QiuYue\|Ci, Yali\|Shi, Lei\|Xu, Caimin\|Huang, Fang\|Hu, Yu
PMID:	27902968

457.
Journal:	Oncotarget. 2017 Mar 7;8(10):16765-16783.
Title:	Genetic variants in the TGFbeta-signaling pathway influence expression of miRNAs in colon and rectal normal mucosa and tumor tissue.
Author:	Slattery, Martha L\|Trivellas, Andromahi\|Pellatt, Andrew J\|Mullany, Lila E\|Stevens, John R\|Wolff, Roger K\|Herrick, Jennifer S
PMID:	28061442

458.
Journal:	Biosci Rep. 2017 Feb 10;37(1). pii: BSR20160432.
Title:	Regulation of PI3K effector signalling in cancer by the phosphoinositide phosphatases.
Author:	Rodgers, Samuel J\|Ferguson, Daniel T\|Mitchell, Christina A\|Ooms, Lisa M
PMID:	28082369

459.
Journal:	Int J Mol Sci. 2017 Jan 19;18(1). pii: ijms18010197.
Title:	Colorectal Carcinoma: A General Overview and Future Perspectives in Colorectal Cancer.
Author:	Marmol, Ines\|Sanchez-de-Diego, Cristina\|Pradilla Dieste, Alberto\|Cerrada, Elena\|Rodriguez Yoldi, Maria Jesus
PMID:	28106826

460.
Journal:	J Clin Pathol. 2017 Aug;70(8):702-711.
Title:	QMC-PCRx: a novel method for rapid mutation detection.
Author:	Ebili, Henry O\|Hassall, James\|Asiri, Abutaleb\|Ham-Karim, Hersh\|Fadhil, Wakkas\|Agboola, Ayodeji Johnson\|Ilyas, Mohammad
PMID:	28153952

461.
Journal:	Cancer Sci. 2017 Apr;108(4):744-752.
Title:	Amino-terminal enhancer of split gene AES encodes a tumor and metastasis suppressor of prostate cancer.
Author:	Okada, Yoshiyuki\|Sonoshita, Masahiro\|Kakizaki, Fumihiko\|Aoyama, Naoki\|Itatani, Yoshiro\|Uegaki, Masayuki\|Sakamoto, Hiromasa\|Kobayashi, Takashi\|Inoue, Takahiro\|Kamba, Tomomi\|Suzuki, Akira\|Ogawa, Osamu\|Taketo, M Mark
PMID:	28178391

462.
Journal:	Int J Oncol. 2017 Mar;50(3):1011-1021.
Title:	TGF-beta1/PTEN/PI3K signaling plays a critical role in the anti-proliferation effect of tetrandrine in human colon cancer cells.
Author:	Chen, Qian-Zhao\|Li, Yang\|Shao, Ying\|Zeng, Yu-Hua\|Ren, Wen-Yan\|Liu, Rong-Xing\|Zhou, Lin-Yun\|Hu, Xue-Lian\|Huang, Ming\|He, Fang\|Sun, Wen-Juan\|Wu, Ke\|He, Bai-Cheng
PMID:	28197642

463.
Journal:	J Gastrointest Oncol. 2017 Feb;8(1):164-172.
Title:	Potential actionable targets in appendiceal cancer detected by immunohistochemistry, fluorescent in situ hybridization, and mutational analysis.
Author:	Borazanci, Erkut\|Millis, Sherri Z\|Kimbrough, Jeffery\|Doll, Nancy\|Von Hoff, Daniel\|Ramanathan, Ramesh K
PMID:	28280620

464.
Journal:	J Cell Biochem. 2017 Oct;118(10):3435-3443.
Title:	STAT1 Inhibits MiR-181a Expression to Suppress Colorectal Cancer Cell Proliferation Through PTEN/Akt.
Author:	Zhang, Xingwen\|Li, Xiang\|Tan, Fengbo\|Yu, Nanhui\|Pei, Haiping
PMID:	28322462

465.
Journal:	Mol Med Rep. 2017 May;15(5):3099-3104.
Title:	Increased phosphorylation of 4Ebinding protein 1 predicts poor prognosis for patients with colorectal cancer.
Author:	Miao, Yufeng\|Chen, Lige\|Shi, Cuifen\|Fan, Rengen\|Chen, Ping\|Liu, Hongqi\|Xia, Aihua\|Qian, Haixin
PMID:	28339030

466.
Journal:	Endocr Relat Cancer. 2017 Jun;24(6):253-265.
Title:	Apc inactivation, but not obesity, synergizes with Pten deficiency to drive intestinal stem cell-derived tumorigenesis.
Author:	Tabrizian, Tahmineh\|Wang, Donghai\|Guan, Fangxia\|Hu, Zunju\|Beck, Amanda P\|Delahaye, Fabien\|Huffman, Derek M
PMID:	28351943

467.
Journal:	Zhonghua Bing Li Xue Za Zhi. 2017 Apr 8;46(4):240-244.
Title:	[Expression characteristics of PTEN and NDRG1 in colorectal carcinoma and their prognostic value].
Author:	Zhang, G X\|Qian, Z Y\|Yang, L J\|Wang, F\|Shen, H
PMID:	28376589

468.
Journal:	Saudi J Biol Sci. 2017 Mar;24(3):466-476.
Title:	Establishment of apoptotic regulatory network for genetic markers of colorectal cancer.
Author:	Hao, Yibin\|Shan, Guoyong\|Nan, Kejun
PMID:	28386169

469.
Journal:	Saudi J Biol Sci. 2017 Mar;24(3):634-643.
Title:	Establishment of apoptotic regulatory network for genetic markers of colorectal cancer and optimal selection of traditional Chinese medicine target.
Author:	Tian, Tongde\|Chen, Chuanliang\|Yang, Feng\|Tang, Jingwen\|Pei, Junwen\|Shi, Bian\|Zhang, Ning\|Zhang, Jianhua
PMID:	28386190

470.
Journal:	Oncotarget. 2017 Jun 13;8(24):39101-39116.
Title:	A novel RON splice variant lacking exon 2 activates the PI3K/AKT pathway via PTEN phosphorylation in colorectal carcinoma cells.
Author:	Ling, Yu\|Kuang, Yeye\|Chen, Lin-Lin\|Lao, Wei-Feng\|Zhu, Yao-Ru\|Wang, Le-Qi\|Wang, Da
PMID:	28388571

471.
Journal:	Oncotarget. 2017 May 30;8(22):36266-36278.
Title:	MicroRNA-22 suppresses the growth, migration and invasion of colorectal cancer cells through a Sp1 negative feedback loop.
Author:	Xia, Shu-Sen\|Zhang, Guang-Jun\|Liu, Zuo-Liang\|Tian, Hong-Peng\|He, Yi\|Meng, Chang-Yuan\|Li, Li-Fa\|Wang, Zi-Wei\|Zhou, Tong
PMID:	28422727

472.
Journal:	Acta Oncol. 2017 May;56(5):639-645.
Title:	Risk factors for brain metastases in patients with metastatic colorectal cancer.
Author:	Christensen, Troels Dreier\|Palshof, Jesper Andreas\|Larsen, Finn Ole\|Hogdall, Estrid\|Poulsen, Tim Svenstrup\|Pfeiffer, Per\|Jensen, Benny Vittrup\|Yilmaz, Mette Karen\|Christensen, Ib Jarle\|Nielsen, Dorte
PMID:	28447565

473.
Journal:	BMC Complement Altern Med. 2017 Apr 28;17(1):236.
Title:	Apoptosis-induced effects of extract from Artemisia annua Linne by modulating PTEN/p53/PDK1/Akt/ signal pathways through PTEN/p53-independent manner in HCT116 colon cancer cells.
Author:	Kim, Eun Ji\|Kim, Guen Tae\|Kim, Bo Min\|Lim, Eun Gyeong\|Kim, Sang-Yong\|Kim, Young Min
PMID:	28454566

474.
Journal:	Clin Neurol Neurosurg. 2017 Jul;158:46-48.
Title:	A rare case of choroid plexus carcinoma that led to the diagnosis of Lynch syndrome (hereditary nonpolyposis colorectal cancer).
Author:	Zhu, Viola W\|Hinduja, Sanjay\|Knezevich, Stevan R\|Silveira, William R\|DeLozier, Celia D
PMID:	28460341

475.
Journal:	Pathologe. 2017 May;38(3):156-163.
Title:	[Hereditary colorectal cancer : An update on genetics and entities in terms of differential diagnosis].
Author:	Rau, T T\|Dawson, H\|Hartmann, A\|Ruschoff, J
PMID:	28474162

476.
Journal:	Endocrinol Metab Clin North Am. 2017 Jun;46(2):503-517.
Title:	Clinical Implications for Germline PTEN Spectrum Disorders.
Author:	Ngeow, Joanne\|Sesock, Kaitlin\|Eng, Charis
PMID:	28476234

477.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2017 May 25;20(5):566-570.
Title:	[MiR-145 inhibits drug resistance to Oxaliplatin in colorectal cancer cells through regulating G protein coupled receptor 98].
Author:	Fu, Qiang\|Cheng, Jing\|Zhang, Jindai\|Zhang, Yonglei\|Chen, Xiaobing\|Xie, Jianguo\|Luo, Suxia
PMID:	28534337

478.
Journal:	Oncol Rep. 2017 Jul;38(1):456-464.
Title:	Resveratrol inactivates PI3K/Akt signaling through upregulating BMP7 in human colon cancer cells.
Author:	Zeng, Yu-Hua\|Zhou, Lin-Yun\|Chen, Qian-Zhao\|Li, Yang\|Shao, Ying\|Ren, Wen-Yan\|Liao, Yun-Peng\|Wang, Han\|Zhu, Jia-Hui\|Huang, Ming\|He, Fang\|Wang, Jin\|Wu, Ke\|He, Bai-Cheng
PMID:	28534975

479.
Journal:	Cell Death Dis. 2017 Jun 1;8(6):e2843.
Title:	The novel hypoxia-inducible factor-1alpha inhibitor IDF-11774 regulates cancer metabolism, thereby suppressing tumor growth.
Author:	Ban, Hyun Seung\|Kim, Bo-Kyung\|Lee, Hongsub\|Kim, Hwan Mook\|Harmalkar, Dipesh\|Nam, Miso\|Park, Song-Kyu\|Lee, Kiho\|Park, Joon-Tae\|Kim, Inhyub\|Lee, Kyeong\|Hwang, Geum-Sook\|Won, Misun
PMID:	28569777

480.
Journal:	Int J Mol Sci. 2017 Jul 5;18(7). pii: ijms18071441.
Title:	Molecular and Clinicopathological Differences by Age at the Diagnosis of Colorectal Cancer.
Author:	Chang, Chu-Cheng\|Lin, Pei-Ching\|Lin, Chun-Chi\|Lan, Yuan-Tzu\|Lin, Hung-Hsin\|Lin, Chien-Hsing\|Yang, Shung-Haur\|Liang, Wen-Yi\|Chen, Wei-Shone\|Jiang, Jeng-Kai\|Lin, Jen-Kou\|Chang, Shih-Ching
PMID:	28678173

481.
Journal:	Adv Med Biol. 2017 1st Quarter;118:83-122.
Title:	Haploinsufficient tumor suppressor genes.
Author:	Inoue, Kazushi\|Fry, Elizabeth A
PMID:	28680740

482.
Journal:	Mol Clin Oncol. 2017 Jul;7(1):113-120.
Title:	Heterogeneity in the colorectal primary tumor and the synchronous resected liver metastases prior to and after treatment with an anti-EGFR monoclonal antibody.
Author:	Adua, Daniela\|Di Fabio, Francesca\|Ercolani, Giorgio\|Fiorentino, Michelangelo\|Gruppioni, Elisa\|Altimari, Annalisa\|Rojas Limpe, Fabiola Lorena\|Normanno, Nicola\|Pinna, Antonio Daniele\|Pinto, Carmine
PMID:	28685087

483.
Journal:	Int J Mol Med. 2017 Sep;40(3):867-874.
Title:	MicroRNA-582 promotes tumorigenesis by targeting phosphatase and tensin homologue in colorectal cancer.
Author:	Song, Bin\|Long, Yanbin\|Liu, Dong\|Zhang, Wen\|Liu, Chang
PMID:	28713947

484.
Journal:	Sci Rep. 2017 Jul 20;7(1):5952.
Title:	PTEN/FOXO3/AKT pathway regulates cell death and mediates morphogenetic differentiation of Colorectal Cancer Cells under Simulated Microgravity.
Author:	Arun, Raj Pranap\|Sivanesan, Divya\|Vidyasekar, Prasanna\|Verma, Rama Shanker
PMID:	28729699

485.
Journal:	Life Sci. 2017 Sep 15;185:63-72.
Title:	M4IDP, a zoledronic acid derivative, induces G1 arrest, apoptosis and autophagy in HCT116 colon carcinoma cells via blocking PI3K/Akt/mTOR pathway.
Author:	Peng, Ying\|Qiu, Ling\|Xu, Dong\|Zhang, Li\|Yu, Huixin\|Ding, Yuedi\|Deng, Lili\|Lin, Jianguo
PMID:	28751160

486.
Journal:	Mol Cancer Ther. 2017 Nov;16(11):2340-2350.
Title:	A Bifunctional MAPK/PI3K Antagonist for Inhibition of Tumor Growth and Metastasis.
Author:	Galban, Stefanie\|Apfelbaum, April A\|Espinoza, Carlos\|Heist, Kevin\|Haley, Henry\|Bedi, Karan\|Ljungman, Mats\|Galban, Craig J\|Luker, Gary D\|Dort, Marcian Van\|Ross, Brian D
PMID:	28775144

487.
Journal:	Sci Rep. 2017 Aug 4;7(1):7312.
Title:	The pseudogene derived from long non-coding RNA DUXAP10 promotes colorectal cancer cell growth through epigenetically silencing of p21 and PTEN.
Author:	Lian, Yifan\|Xu, Yetao\|Xiao, Chuanxing\|Xia, Rui\|Gong, Huangbo\|Yang, Peng\|Chen, Tao\|Wu, Dongdong\|Cai, Zeling\|Zhang, Jianping\|Wang, Keming
PMID:	28779166

488.
Journal:	Biomed Pharmacother. 2017 Oct;94:1094-1100.
Title:	Leuconostoc mesenteroides-derived anticancer pharmaceuticals hinder inflammation and cell survival in colon cancer cells by modulating NF-kappaB/AKT/PTEN/MAPK pathways.
Author:	Zununi Vahed, Sepideh\|Barzegari, Abolfazl\|Rahbar Saadat, Yalda\|Goreyshi, Ali\|Omidi, Yadollah
PMID:	28821160

489.
Journal:	Jpn J Radiol. 2017 Nov;35(11):664-672.
Title:	Involvement of miR-155/FOXO3a and miR-222/PTEN in acquired radioresistance of colorectal cancer cell line.
Author:	Khoshinani, Hamed Manoochehri\|Afshar, Saeid\|Pashaki, Abdolazim Sedighi\|Mahdavinezhad, Ali\|Nikzad, Safora\|Najafi, Rezvan\|Amini, Razieh\|Gholami, Mohammad Hadi\|Khoshghadam, Alireza\|Saidijam, Massoud
PMID:	28879560

490.
Journal:	Neoplasia. 2017 Oct;19(10):830-841.
Title:	Chk1 Inhibitor SCH900776 Effectively Potentiates the Cytotoxic Effects of Platinum-Based Chemotherapeutic Drugs in Human Colon Cancer Cells.
Author:	Herudkova, Jarmila\|Paruch, Kamil\|Khirsariya, Prashant\|Soucek, Karel\|Krkoska, Martin\|Vondalova Blanarova, Olga\|Sova, Petr\|Kozubik, Alois\|Hyrslova Vaculova, Alena
PMID:	28888100

491.
Journal:	Tumour Biol. 2017 Sep;39(9):1010428317724517.
Title:	EGFR pathway subgroups in Chilean colorectal cancer patients, detected by mutational and expression profiles, associated to different clinicopathological features.
Author:	Alvarez, Karin\|Orellana, Paulina\|Villarroel, Cynthia\|Contreras, Luis\|Kawachi, Hiroshi\|Kobayashi, Maki\|Wielandt, Ana Maria\|De la Fuente, Marjorie\|Trivino, Juan Carlos\|Kronberg, Udo\|Carvallo, Pilar\|Lopez-Kostner, Francisco
PMID:	28936923

492.
Journal:	PLoS One. 2017 Sep 28;12(9):e0185607.
Title:	High mRNA expression of splice variant SYK short correlates with hepatic disease progression in chemonaive lymph node negative colon cancer patients.
Author:	Coebergh van den Braak, Robert R J\|Sieuwerts, Anieta M\|Kandimalla, Raju\|Lalmahomed, Zarina S\|Bril, Sandra I\|van Galen, Anne\|Smid, Marcel\|Biermann, Katharina\|van Krieken, J Han J M\|Kloosterman, Wigard P\|Foekens, John A\|Goel, Ajay\|Martens, John W M\|IJzerman
PMID:	28957395

493.
Journal:	Cell Physiol Biochem. 2017;43(3):945-958.
Title:	MicroRNA-21 (Mir-21) Promotes Cell Growth and Invasion by Repressing Tumor Suppressor PTEN in Colorectal Cancer.
Author:	Wu, Yiying\|Song, Yi\|Xiong, Yao\|Wang, Xiaodong\|Xu, Ke\|Han, Bin\|Bai, Yang\|Li, Li\|Zhang, Yuanyuan\|Zhou, Liming
PMID:	28957811

494.
Journal:	Am J Transl Res. 2017 Sep 15;9(9):4026-4035. eCollection 2017.
Title:	TUSC7 acts as a tumor suppressor in colorectal cancer.
Author:	Ren, Weidan\|Chen, Shuo\|Liu, Guiwei\|Wang, Xuesong\|Ye, Haopeng\|Xi, Yanguo
PMID:	28979678

495.
Journal:	Cancer Biomark. 2017 Dec 12;21(1):123-133.
Title:	Knockdown of lncRNA CCAT2 inhibits endometrial cancer cells growth and metastasis via sponging miR-216b.
Author:	Xie, Pengmu\|Cao, Hongying\|Li, Ying\|Wang, Jianhua\|Cui, Zhumei
PMID:	29036788

496.
Journal:	Mol Med Rep. 2017 Dec;16(6):9692-9700.
Title:	MicroRNA760 inhibits cell proliferation and invasion of colorectal cancer by targeting the SP1mediated PTEN/AKT signalling pathway.
Author:	Li, Xiaoyan\|Ding, Yuansheng\|Liu, Naiqing\|Sun, Qinli\|Zhang, Jie
PMID:	29039575

497.
Journal:	Zhongguo Zhong Yao Za Zhi. 2017 May;42(9):1730-1735.
Title:	[Effect of resveratrol in regulating proliferation and apoptosis of rectal cancer cells via up-regulating PTEN].
Author:	Lao, Ling-Juan\|Song, Xin-Jiang\|Xu, Jia
PMID:	29082697

498.
Journal:	Oncotarget. 2017 Sep 28;8(48):84426-84433.
Title:	Tumor-biopsy stratification based on mTOR-pathway activity and functional mutations in the upstream genes PIK3CA and PTEN.
Author:	Laes, Jean-Francois\|Sauvage, Sebastien\|Ghitti, Gregori
PMID:	29137436

499.
Journal:	Braz J Med Biol Res. 2017 Nov 13;51(1):e6472.
Title:	Exosomes promote cetuximab resistance via the PTEN/Akt pathway in colon cancer cells.
Author:	Zhang, S\|Zhang, Y\|Qu, J\|Che, X\|Fan, Y\|Hou, K\|Guo, T\|Deng, G\|Song, N\|Li, C\|Wan, X\|Qu, X\|Liu, Y
PMID:	29160412

500.
Journal:	Oncotarget. 2017 Aug 24;8(55):93567-93579.
Title:	Comprehensive genomic sequencing detects important genetic differences between right-sided and left-sided colorectal cancer.
Author:	Shimada, Yoshifumi\|Kameyama, Hitoshi\|Nagahashi, Masayuki\|Ichikawa, Hiroshi\|Muneoka, Yusuke\|Yagi, Ryoma\|Tajima, Yosuke\|Okamura, Takuma\|Nakano, Masato\|Sakata, Jun\|Kobayashi, Takashi\|Nogami, Hitoshi\|Maruyama, Satoshi\|Takii, Yasumasa\|Hayashida, Tetsu\|Takaishi
PMID:	29212173

501.
Journal:	Biomed Pharmacother. 2017 Dec;96:974-981.
Title:	miRNA-495 suppresses proliferation and migration of colorectal cancer cells by targeting FAM83D.
Author:	Yan, Likun\|Yao, Jianfeng\|Qiu, Jian
PMID:	29221726

502.
Journal:	Oncotarget. 2017 Sep 27;8(62):105072-105080.
Title:	Targeted next generation sequencing in Chinese colorectal cancer patients guided anti-EGFR treatment and facilitated precision cancer medicine.
Author:	Hou, Helei\|Liu, Dong\|Zhang, Chuantao\|Jiang, Yanxia\|Lu, Guifang\|Zhou, Na\|Yang, Xiaonan\|Zhang, Xiaoping\|Li, Zhuokun\|Zhu, Hongmei\|Qian, Zhaoyang\|Zhang, Xiaochun
PMID:	29285234

503.
Journal:	Saudi J Biol Sci. 2017 Dec;24(8):1781-1786.
Title:	Establishment of optimal regulatory network of colorectal cancer based on p42.3 protein.
Author:	Hao, Yibin\|Zhang, Jianhua\|Shan, Guoyong\|Zhang, Ning\|Jin, Wenwen\|Nan, Kejun
PMID:	29551923

504.
Journal:	Pathol Oncol Res. 2018 Jan;24(1):145-151.
Title:	The Effect of miR-200c Inhibition on Chemosensitivity (5- FluoroUracil) in Colorectal Cancer.
Author:	Heydari, Korosh\|Saidijam, Massoud\|Sharifi, Mohammad Reza\|Dermani, Fatemeh Karimi\|Soleimani Asl, Sara\|Shabab, Nooshin\|Najafi, Rezvan
PMID:	28411308

505.
Journal:	J Cell Biochem. 2018 Feb;119(2):2356-2367.
Title:	Effects of Glut1 gene silencing on proliferation, differentiation, and apoptosis of colorectal cancer cells by targeting the TGF-beta/PI3K-AKT-mTOR signaling pathway.
Author:	Wu, Xue-Liang\|Wang, Li-Kun\|Yang, Dong-Dong\|Qu, Ming\|Yang, Yong-Jiang\|Guo, Fei\|Han, Lei\|Xue, Jun
PMID:	28884839

506.
Journal:	Oncogene. 2018 Jan 25;37(4):427-438.
Title:	AKT overactivation can suppress DNA repair via p70S6 kinase-dependent downregulation of MRE11.
Author:	Piscitello, D\|Varshney, D\|Lilla, S\|Vizioli, M G\|Reid, C\|Gorbunova, V\|Seluanov, A\|Gillespie, D A\|Adams, P D
PMID:	28967905

507.
Journal:	Mol Med Rep. 2018 Jan;17(1):358-365.
Title:	Hedyotis diffusa Willd inhibits proliferation and induces apoptosis of 5FU resistant colorectal cancer cells by regulating the PI3K/AKT signaling pathway.
Author:	Li, Qiongyu\|Lai, Zijun\|Yan, Zhaokun\|Peng, Jun\|Jin, Yiyi\|Wei, Lihui\|Lin, Jiumao
PMID:	29115462

508.
Journal:	Clin Colorectal Cancer. 2018 Mar;17(1):73-79.
Title:	Molecular Profiling of Patients With Advanced Colorectal Cancer: Princess Margaret Cancer Centre Experience.
Author:	Chiu, Joanne W\|Krzyzanowska, Monika K\|Serra, Stefano\|Knox, Jennifer J\|Dhani, Neesha C\|Mackay, Helen\|Hedley, David\|Moore, Malcolm\|Liu, Geoffrey\|Burkes, Ronald L\|Brezden-Masley, Christine\|Roehrl, Michael H\|Craddock, Kenneth J\|Tsao, Ming-Sound\|Zhang, Tong\|Yu
PMID:	29128266

509.
Journal:	Cancer Sci. 2018 Feb;109(2):354-362.
Title:	MicroRNA 26b promotes colorectal cancer metastasis by downregulating phosphatase and tensin homolog and wingless-type MMTV integration site family member 5A.
Author:	Fan, Dejun\|Lin, Xutao\|Zhang, Feng\|Zhong, Weijie\|Hu, Jiancong\|Chen, Yufeng\|Cai, Zerong\|Zou, Yifeng\|He, Xiaowen\|Chen, Xiuting\|Lan, Ping\|Wu, Xiaojian
PMID:	29160937

510.
Journal:	Clin Cancer Res. 2018 Mar 1;24(5):1062-1072.
Title:	Classifying Colorectal Cancer by Tumor Location Rather than Sidedness Highlights a Continuum in Mutation Profiles and Consensus Molecular Subtypes.
Author:	Loree, Jonathan M\|Pereira, Allan A L\|Lam, Michael\|Willauer, Alexandra N\|Raghav, Kanwal\|Dasari, Arvind\|Morris, Van K\|Advani, Shailesh\|Menter, David G\|Eng, Cathy\|Shaw, Kenna\|Broaddus, Russell\|Routbort, Mark J\|Liu, Yusha\|Morris, Jeffrey S\|Luthra, Rajyalakshm
PMID:	29180604

511.
Journal:	Cancer. 2018 Mar 1;124(5):1070-1082.
Title:	A mutational comparison of adult and adolescent and young adult (AYA) colon cancer.
Author:	Tricoli, James V\|Boardman, Lisa A\|Patidar, Rajesh\|Sindiri, Sivasish\|Jang, Jin S\|Walsh, William D\|McGregor, Paul M 3rd\|Camalier, Corinne E\|Mehaffey, Michele G\|Furman, Wayne L\|Bahrami, Armita\|Williams, P Mickey\|Lih, Chih-Jian\|Conley, Barbara A\|Khan, Javed
PMID:	29194591

512.
Journal:	Oncol Rep. 2018 Mar;39(3):1516-1522.
Title:	Fucoidan downregulates insulin-like growth factor-I receptor levels in HT-29 human colon cancer cells.
Author:	Kim, In-Hye\|Nam, Taek-Jeong
PMID:	29328495

513.
Journal:	BMC Biol. 2018 Jan 10;16(1):3.
Title:	A role for endothelial nitric oxide synthase in intestinal stem cell proliferation and mesenchymal colorectal cancer.
Author:	Penarando, Jon\|Lopez-Sanchez, Laura M\|Mena, Rafael\|Guil-Luna, Silvia\|Conde, Francisco\|Hernandez, Vanessa\|Toledano, Marta\|Gudino, Victoria\|Raponi, Michela\|Billard, Caroline\|Villar, Carlos\|Diaz, Cesar\|Gomez-Barbadillo, Jose\|De la Haba-Rodriguez, Juan\|Myant,
PMID:	29329541

514.
Journal:	Biochem Biophys Res Commun. 2018 Jan 13. pii: S0006-291X(18)30067-6.
Title:	TEMPORARY REMOVAL: Inhibition of COX-2 and 5-LOX regulates the progression of colorectal cancer by promoting PTEN and suppressing PI3K/AKT pathway.
Author:	Chang, Jian\|Tang, Nan\|Fang, Qi\|Zhu, Kongfan\|Liu, Lei\|Xiong, Xingcheng\|Zhu, Zhongchao\|Zhang, Bixiang\|Zhang, Mingzhi\|Tao, Jing
PMID:	29339153

515.
Journal:	Oncol Lett. 2018 Jan;15(1):1236-1240.
Title:	Assessment of PI3K/AKT/PTEN signaling pathway activity in colorectal cancer using quantum dot-conjugated antibodies.
Author:	Waniczek, Dariusz\|Snietura, Miroslaw\|Lorenc, Zbigniew\|Nowakowska-Zajdel, Ewa\|Muc-Wierzgon, Malgorzata
PMID:	29422975

516.
Journal:	Nat Med. 2018 Mar;24(3):262-270.
Title:	DKK2 imparts tumor immunity evasion through beta-catenin-independent suppression of cytotoxic immune-cell activation.
Author:	Xiao, Qian\|Wu, Jibo\|Wang, Wei-Jia\|Chen, Shiyang\|Zheng, Yingxia\|Yu, Xiaoqing\|Meeth, Katrina\|Sahraei, Mahnaz\|Bothwell, Alfred L M\|Chen, Lieping\|Bosenberg, Marcus\|Chen, Jianfeng\|Sexl, Veronika\|Sun, Le\|Li, Lin\|Tang, Wenwen\|Wu, Dianqing
PMID:	29431745

517.
Journal:	Oncol Lett. 2018 Mar;15(3):3197-3201.
Title:	mir-106a regulates cell proliferation and apoptosis of colon cancer cells through targeting the PTEN/PI3K/AKT signaling pathway.
Author:	Qin, Yan\|Huo, Zhibin\|Song, Xiang\|Chen, Xiao\|Tian, Xiaopeng\|Wang, Xinjie
PMID:	29435057

518.
Journal:	Cold Spring Harb Mol Case Stud. 2018 Apr 2;4(2). pii: mcs.a002535.
Title:	Molecular characterization of ERBB2-amplified colorectal cancer identifies potential mechanisms of resistance to targeted therapies: a report of two instructive cases.
Author:	Owen, Daniel R\|Wong, Hui-Li\|Bonakdar, Melika\|Jones, Martin\|Hughes, Christopher S\|Morin, Gregg B\|Jones, Steven J M\|Renouf, Daniel J\|Lim, Howard\|Laskin, Janessa\|Marra, Marco\|Yip, Stephen\|Schaeffer, David F
PMID:	29438965

519.
Journal:	Cancer Med. 2018 Mar;7(3):809-819.
Title:	High expression of DJ-1 promotes growth and invasion via the PTEN-AKT pathway and predicts a poor prognosis in colorectal cancer.
Author:	Lin, Yong\|Chen, Qian\|Liu, Quan-Xing\|Zhou, Dong\|Lu, Xiao\|Deng, Xu-Feng\|Yang, Hua\|Zheng, Hong\|Qiu, Yuan
PMID:	29441725

520.
Journal:	Cancer Lett. 2018 May 1;421:161-169.
Title:	Combination of Kras activation and PTEN deletion contributes to murine hepatopancreatic ductal malignancy.
Author:	Lin, Yun-Kai\|Fang, Zheng\|Jiang, Tian-Yi\|Wan, Zheng-Hua\|Pan, Yu-Fei\|Ma, Yun-Han\|Shi, Yuan-Yuan\|Tan, Ye-Xiong\|Dong, Li-Wei\|Zhang, Yong-Jie\|Wang, Hong-Yang
PMID:	29452147

521.
Journal:	Am J Cancer Res. 2018 Feb 1;8(2):256-265. eCollection 2018.
Title:	High expression of WWP1 predicts poor prognosis and associates with tumor progression in human colorectal cancer.
Author:	Chen, Jian-Jun\|Zhang, Wei
PMID:	29511596

522.
Journal:	J Exp Clin Cancer Res. 2018 Mar 12;37(1):54.
Title:	Stearoyl-CoA desaturase-1 promotes colorectal cancer metastasis in response to glucose by suppressing PTEN.
Author:	Ran, Hui\|Zhu, Yemin\|Deng, Ruyuan\|Zhang, Qi\|Liu, Xisheng\|Feng, Ming\|Zhong, Jie\|Lin, Shuhai\|Tong, Xuemei\|Su, Qing
PMID:	29530061

523.
Journal:	Acta Biochim Biophys Sin (Shanghai). 2018 Apr 1;50(4):355-361.
Title:	BRAF and EGFR inhibitors synergize to increase cytotoxic effects and decrease stem cell capacities in BRAF(V600E)-mutant colorectal cancer cells.
Author:	Wu, Zhenhua\|Huang, Mingzhu\|Gong, Yiwei\|Lin, Chen\|Guo, Weijian
PMID:	29534162

524.
Journal:	Int J Cancer. 2018 Aug 1;143(3):668-678.
Title:	A non-canonical tumor suppressive role for the long non-coding RNA MALAT1 in colon and breast cancers.
Author:	Kwok, Zhi Hao\|Roche, Veronique\|Chew, Xiao Hong\|Fadieieva, Anastasiia\|Tay, Yvonne
PMID:	29574704

525.
Journal:	Anticancer Res. 2018 Apr;38(4):2235-2240.
Title:	Racial Disparities in the Molecular Landscape of Cancer.
Author:	Heath, Elisabeth I\|Lynce, Filipa\|Xiu, Joanne\|Ellerbrock, Angela\|Reddy, Sandeep K\|Obeid, Elias\|Liu, Stephen V\|Bollig-Fischer, Aliccia\|Separovic, Duska\|Vanderwalde, Ari
PMID:	29599344

526.
Journal:	Cesk Patol. 2018 Spring;54(1):17-21.
Title:	[Prediction of EGFR blockade responses in metastatic colorectal carcinoma].
Author:	Fabian, Pavel\|Nemecek, Radim
PMID:	29631407

527.
Journal:	Mol Pharm. 2018 Jun 4;15(6):2316-2326.
Title:	Nanoencapsulation of Novel Inhibitors of PNKP for Selective Sensitization to Ionizing Radiation and Irinotecan and Induction of Synthetic Lethality.
Author:	Shire, Zahra\|Vakili, Mohammad Reza\|Morgan, Timothy D R\|Hall, Dennis G\|Lavasanifar, Afsaneh\|Weinfeld, Michael
PMID:	29688721

528.
Journal:	BMC Med Genomics. 2018 Apr 20;11(Suppl 2):29.
Title:	Population-based statistical inference for temporal sequence of somatic mutations in cancer genomes.
Author:	Rhee, Je-Keun\|Kim, Tae-Min
PMID:	29697365

529.
Journal:	Oncotarget. 2018 Apr 13;9(28):19911-19928.
Title:	Over-activation of AKT signaling leading to 5-Fluorouracil resistance in SNU-C5/5-FU cells.
Author:	Kim, Eun-Ji\|Kang, Gyeoung-Jin\|Kang, Jung-Il\|Boo, Hye-Jin\|Hyun, Jin Won\|Koh, Young Sang\|Chang, Weon-Young\|Kim, Young Ree\|Kwon, Jung-Mi\|Maeng, Young Hee\|Yoo, Eun-Sook\|Lee, Chang Hoon\|Kang, Hee-Kyoung
PMID:	29731993

530.
Journal:	Immunology. 2018 Oct;155(2):263-272.
Title:	Tumour YAP1 and PTEN expression correlates with tumour-associated myeloid suppressor cell expansion and reduced survival in colorectal cancer.
Author:	Yang, Rong\|Cai, Ting-Ting\|Wu, Xiao-Jun\|Liu, Yi-Na\|He, Jia\|Zhang, Xiao-Shi\|Ma, Gang\|Li, Jiang
PMID:	29770434

531.
Journal:	Cancer Med. 2018 May 17.
Title:	Primary tumor sidedness is an independent prognostic marker for survival in metastatic colorectal cancer: Results from a large retrospective cohort with mutational analysis.
Author:	Kamran, Sophia C\|Clark, Jeffrey W\|Zheng, Hui\|Borger, Darrell R\|Blaszkowsky, Lawrence S\|Allen, Jill N\|Kwak, Eunice L\|Wo, Jennifer Y\|Parikh, Aparna R\|Nipp, Ryan D\|Murphy, Janet E\|Goyal, Lipika\|Zhu, Andrew X\|Iafrate, A John\|Corcoran, Ryan B\|Ryan, David P\|Hon
PMID:	29771009

532.
Journal:	Gynecol Oncol. 2018 Jul;150(1):127-135.
Title:	Massively parallel sequencing analysis of mucinous ovarian carcinomas: genomic profiling and differential diagnoses.
Author:	Mueller, Jennifer J\|Schlappe, Brooke A\|Kumar, Rahul\|Olvera, Narciso\|Dao, Fanny\|Abu-Rustum, Nadeem\|Aghajanian, Carol\|DeLair, Deborah\|Hussein, Yaser R\|Soslow, Robert A\|Levine, Douglas A\|Weigelt, Britta
PMID:	29793804

533.
Journal:	Cell Death Dis. 2018 Jun 4;9(6):673.
Title:	Decreased expression of ARHGAP15 promotes the development of colorectal cancer through PTEN/AKT/FOXO1 axis.
Author:	Pan, Shengli\|Deng, Yingying\|Fu, Jun\|Zhang, Yuhao\|Zhang, Zhijin\|Ru, Xiaokun\|Qin, Xianju
PMID:	29867200

534.
Journal:	Genet Test Mol Biomarkers. 2018 Jun;22(6):390-397.
Title:	Upregulation of HOXA10 Protein Expression Predicts Poor Prognosis for Colorectal Cancer.
Author:	Yuan, Yuan\|Sun, Sanyuan\|Jiao, Nanlin\|Shu, Yongqian\|Zhang, Youwei
PMID:	29870276

535.
Journal:	Bioorg Med Chem. 2018 Aug 7;26(14):3899-3908.
Title:	Facile construction of fused benzimidazole-isoquinolinones that induce cell-cycle arrest and apoptosis in colorectal cancer cells.
Author:	He, Liu-Jun\|Yang, Dong-Lin\|Li, Shi-Qiang\|Zhang, Ya-Jun\|Tang, Yan\|Lei, Jie\|Frett, Brendan\|Lin, Hui-Kuan\|Li, Hong-Yu\|Chen, Zhong-Zhu\|Xu, Zhi-Gang
PMID:	29921474

536.
Journal:	Biomed Pharmacother. 2018 Oct;106:109-116.
Title:	Sirtuin 6 inhibits colon cancer progression by modulating PTEN/AKT signaling.
Author:	Tian, Junhong\|Yuan, Leilei
PMID:	29957460

537.
Journal:	Eur J Hum Genet. 2018 Jul 2. pii: 10.1038/s41431-018-0207-2.
Title:	Optimization of the diagnosis of inherited colorectal cancer using NGS and capture of exonic and intronic sequences of panel genes.
Author:	Baert-Desurmont, Stephanie\|Coutant, Sophie\|Charbonnier, Francoise\|Macquere, Pierre\|Lecoquierre, Francois\|Schwartz, Mathias\|Blanluet, Maud\|Vezain, Myriam\|Lanos, Raphael\|Quenez, Olivier\|Bou, Jacqueline\|Bouvignies, Emilie\|Fourneaux, Steeve\|Manase, Sandrine\|V
PMID:	29967336

538.
Journal:	World J Surg Oncol. 2018 Jul 5;16(1):128.
Title:	Differences in gene mutations according to gender among patients with colorectal cancer.
Author:	Tsai, Yi-Jian\|Huang, Sheng-Chieh\|Lin, Hung-Hsin\|Lin, Chun-Chi\|Lan, Yuan-Tzu\|Wang, Huann-Sheng\|Yang, Shung-Haur\|Jiang, Jeng-Kai\|Chen, Wei-Shone\|Lin, Tzu-Chen\|Lin, Jen-Kou\|Chang, Shih-Ching
PMID:	29976257

539.
Journal:	Appl Immunohistochem Mol Morphol. 2018 Jul 5.
Title:	Colorectal Cancer Stratification in the Routine Clinical Pathway: A District General Hospital Experience.
Author:	Wedden, Sarah\|Miller, Keith\|Frayling, Ian M\|Thomas, Teresa\|Chefani, Alina\|Miller, Karolina\|Hamblin, Angela\|Taylor, Jenny C\|D'Arrigo, Corrado
PMID:	29985199

540.
Journal:	Oncol Lett. 2018 Aug;16(2):2638-2644.
Title:	miRNA-29a inhibits colon cancer growth by regulation of the PTEN/Akt/GSK3beta and Wnt/beta-catenin signaling pathways.
Author:	Han, Xiaofeng\|Zheng, Jianwei\|Wang, Yunlei\|Gao, Zhigang
PMID:	30013659

541.
Journal:	Biomed Pharmacother. 2018 Sep;105:1172-1182.
Title:	Sirt3-mediated mitochondrial fission regulates the colorectal cancer stress response by modulating the Akt/PTEN signalling pathway.
Author:	Wang, Yan\|Sun, Xiaohui\|Ji, Kaihua\|Du, Liqing\|Xu, Chang\|He, Ningning\|Wang, Jinhan\|Liu, Yang\|Liu, Qiang
PMID:	30021354

542.
Journal:	Biochim Biophys Acta Gen Subj. 2018 Jul 20;1862(10):2281-2292.
Title:	Metabolic reprogramming in colon cancer reversed by DHTS through regulating PTEN/AKT/HIF1alpha mediated signal pathway.
Author:	Wang, Lin\|Yu, Ziru\|Ren, Shuyue\|Song, Junke\|Wang, Jinhua\|Du, Guanhua
PMID:	30036603

543.
Journal:	Cell Physiol Biochem. 2018;48(3):1259-1273.
Title:	Upregulation of RASSF1A in Colon Cancer by Suppression of Angiogenesis Signaling and Akt Activation.
Author:	Blanchard, Thomas G\|Lapidus, Rena\|Banerjee, Vivekjyoti\|Bafford, Andrea C\|Czinn, Steven J\|Ahmed, Hafiz\|Banerjee, Aditi
PMID:	30045022

544.
Journal:	J Exp Clin Cancer Res. 2018 Jul 31;37(1):178.
Title:	High expression of Ras-related protein 1A promotes an aggressive phenotype in colorectal cancer via PTEN/FOXO3/CCND1 pathway.
Author:	Liu, Liguo\|Yan, Xuebing\|Wu, Dapeng\|Yang, Yi\|Li, Mengcheng\|Su, Yang\|Yang, Wenchao\|Shan, Zezhi\|Gao, Yuping\|Jin, Zhiming
PMID:	30064475

545.
Journal:	Ann Saudi Med. 2018 Jul-Aug;38(4):251-259.
Title:	Molecular characteristics of colorectal cancer in a Middle Eastern population in a single institution.
Author:	Ibrahim, Tony\|Saer-Ghorra, Claude\|Trak-Smayra, Vivane\|Nadiri, Samah\|Yazbeck, Charbel\|Baz, Maria\|Kattan, Joseph G
PMID:	30078023

546.
Journal:	Cancer Lett. 2018 Nov 1;436:28-37.
Title:	PTEN deficiency confers colorectal cancer cell resistance to dual inhibitors of FLT3 and aurora kinase A.
Author:	Liu, Yifan\|Yang, Eun Ju\|Zhang, Baoyuan\|Miao, Zhengqiang\|Wu, Changjie\|Lyu, Junfang\|Tan, Kaeling\|Poon, Terence Chuen Wai\|Shim, Joong Sup
PMID:	30118842

547.
Journal:	Biomed Pharmacother. 2018 Oct;106:1370-1377.
Title:	MiR-92a promotes tumorigenesis of colorectal cancer, a transcriptomic and functional based study.
Author:	Chen, Erfei\|Li, Qiqi\|Wang, Hua\|Yang, Fangfang\|Min, Lulu\|Yang, Jin
PMID:	30119209

548.
Journal:	J Cell Mol Med. 2018 Aug 22.
Title:	LINC00312 represses proliferation and metastasis of colorectal cancer cells by regulation of miR-21.
Author:	Li, Gang\|Wang, Changming\|Wang, Yongbing\|Xu, Bin\|Zhang, Wenzhong
PMID:	30134003

549.
Journal:	Exp Ther Med. 2018 Sep;16(3):1758-1765.
Title:	Gambogic acid regulates the migration and invasion of colorectal cancer via microRNA-21-mediated activation of phosphatase and tensin homolog.
Author:	Gao, Guangyi\|Bian, Yinzhu\|Qian, Hanqing\|Yang, Mi\|Hu, Jing\|Li, Li\|Yu, Lixia\|Liu, Baorui\|Qian, Xiaoping
PMID:	30186399

550.
Journal:	Mol Cancer Res. 2018 Sep 10. pii: 1541-7786.MCR-18-0650.
Title:	Repurposing of mTOR Complex inhibitors Attenuates MCL-1 and sensitizes to PARP inhibition.
Author:	Mattoo, Abid R\|Joun, Alex\|Jessup, J Milburn
PMID:	30201826

551.
Journal:	Cancer Cell Int. 2018 Sep 6;18:131.
Title:	Assessment of intratumor immune-microenvironment in colorectal cancers with extranodal extension of nodal metastases.
Author:	Fassan, Matteo\|Vianello, Luca\|Sacchi, Diana\|Fanelli, Giuseppe N\|Munari, Giada\|Scarpa, Marco\|Cappellesso, Rocco\|Loupakis, Fotios\|Lanza, Cristiano\|Salmaso, Roberta\|Mescoli, Claudia\|Valeri, Nicola\|Agostini, Marco\|D'Angelo, Edoardo\|Lonardi, Sara\|Pucciarelli,
PMID:	30202242

552.
Journal:	J Pathol. 2018 Sep 11.
Title:	Tumor suppressive function of E2F-1 on PTEN-induced serrated colorectal carcinogenesis.
Author:	Dosil, Maria Alba\|Navaridas, Raul\|Mirantes, Cristina\|Tarragona, Jordi\|Eritja, Nuria\|Felip, Isidre\|Urdanibia, Izaskun\|Megino, Cristina\|Domingo, Monica\|Santacana, Maria\|Gatius, Sonia\|Pinol, Carme\|Barcelo, Carla\|Maiques, Oscar\|Macia, Anna\|Velasco, Ana\|Vaquer
PMID:	30206933

553.
Journal:	Eur Rev Med Pharmacol Sci. 2018 Sep;22(17):5499-5507.
Title:	Down-regulation of miR-29a facilitates apoptosis of colorectal carcinoma cell SW480 and suppresses its Paclitaxel resistance.
Author:	Yuan, L-L\|Li, L\|Liu, J-N\|Mei, J\|Lei, C-J
PMID:	30229821

554.
Journal:	Biomed Pharmacother. 2018 Nov;107:1712-1719.
Title:	F-box and leucine-rich repeat protein 5 promotes colon cancer progression by modulating PTEN/PI3K/AKT signaling pathway.
Author:	Yao, Hui\|Su, Song\|Xia, Dong\|Wang, Mingming\|Li, Zonglin\|Chen, Wangsheng\|Ren, Lei\|Xu, Liang
PMID:	30257389

555.
Journal:	Biochim Biophys Acta Mol Basis Dis. 2018 Oct 4;1864(12):3746-3758.
Title:	Differential expression of tumor-associated genes and altered gut microbiome with decreased Akkermansia muciniphila confer a tumor-preventive microenvironment in intestinal epithelial Pten-deficient mice.
Author:	Howe, Cody\|Kim, Su Jin\|Mitchell, Jonathon\|Im, Eunok\|Kim, Yong Sung\|Kim, You Sun\|Rhee, Sang Hoon
PMID:	30292635

556.
Journal:	Fam Cancer. 2018 Oct 9. pii: 10.1007/s10689-018-0110-6.
Title:	Boosting care and knowledge about hereditary cancer: European Reference Network on Genetic Tumour Risk Syndromes.
Author:	Vos, Janet R\|Giepmans, Lisette\|Rohl, Claas\|Geverink, Nicoline\|Hoogerbrugge, Nicoline
PMID:	30302652

557.
Journal:	Probiotics Antimicrob Proteins. 2018 Oct 11. pii: 10.1007/s12602-018-9478-8.
Title:	Effects of Lactobacillus acidophilus and Bifidobacterium bifidum Probiotics on the Expression of MicroRNAs 135b, 26b, 18a and 155, and Their Involving Genes in Mice Colon Cancer.
Author:	Heydari, Zahra\|Rahaie, Mahdi\|Alizadeh, Ali Mohammad\|Agah, Shahram\|Khalighfard, Solmaz\|Bahmani, Sahar
PMID:	30311185

558.
Journal:	Ecotoxicol Environ Saf. 2018 Oct 9;167:107-113.
Title:	Microcystin-LR promotes migration via the cooperation between microRNA-221/PTEN and STAT3 signal pathway in colon cancer cell line DLD-1.
Author:	Ren, Yan\|Yang, Mengli\|Ma, Rong\|Gong, Ying\|Zou, Yuntao\|Wang, Ting\|Wu, Jianzhong
PMID:	30312888

559.
Journal:	J Cell Physiol. 2018 Oct 14.
Title:	Diagnostic, prognostic, and therapeutic potency of microRNA 21 in the pathogenesis of colon cancer, current status and prospective.
Author:	Bahreyni, Amirhossein\|Rezaei, Melika\|Bahrami, Afsane\|Khazaei, Majid\|Fiuji, Hamid\|Ryzhikov, Mikhail\|Ferns, Gordon A\|Avan, Amir\|Hassanian, Seyed Mahdi
PMID:	30317621

560.
Journal:	Oncol Lett. 2018 Nov;16(5):5923-5929.
Title:	Doxorubicin resistance induces IL6 activation in the colon cancer cell line LS180.
Author:	Li, Xiao-Yun\|Liao, Xiao-Feng\|Wang, Hong-Bo\|Zhang, Jian
PMID:	30344742