Literatures

Primary Site >> Biliary tract Cancer

Gene >> PTEN

1.
Journal:	Anticancer Res. 2002 May-Jun;22(3):1529-36.
Title:	Allelotype analysis of the PTEN, Smad4 and DCC genes in biliary tract cancer.
Author:	Suto, Takayuki\|Sugai, Tamotsu\|Habano, Wataru\|Uesugi, Noriyuki\|Kanno, Senji\|Saito, Kazuyoshi\|Nakamura, Shin-ichi
PMID:	12168833

2.
Journal:	Hepatology. 2003 Apr;37(4):852-61.
Title:	Homozygous deletion scanning in hepatobiliary tumor cell lines reveals alternative pathways for liver carcinogenesis.
Author:	Pineau, Pascal\|Marchio, Agnes\|Nagamori, Seishi\|Seki, Shuichi\|Tiollais, Pierre\|Dejean, Anne
PMID:	12668978

3.
Journal:	Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2005 Feb;30(1):46-8.
Title:	[Expression and significance of PTEN and nm23 in the metastasis of gallbladder cancer].
Author:	Zheng, Chang-Li\|Wen, Ji-Fang\|Huang, Ying
PMID:	15875318

4.
Journal:	J Clin Invest. 2006 Jul;116(7):1843-52. Epub 2006 Jun 8.
Title:	Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption of Smad4 and Pten in mice.
Author:	Xu, Xiaoling\|Kobayashi, Shogo\|Qiao, Wenhui\|Li, Cuiling\|Xiao, Cuiying\|Radaeva, Svetlana\|Stiles, Bangyan\|Wang, Rui-Hong\|Ohara, Nobuya\|Yoshino, Tadashi\|LeRoith, Derek\|Torbenson, Michael S\|Gores, Gregory J\|Wu, Hong\|Gao, Bin\|Deng, Chu-Xia
PMID:	16767220

5.
Journal:	Pathol Oncol Res. 2007;13(4):326-35. Epub 2007 Dec 25.
Title:	Significance of PML and p53 protein as molecular prognostic markers of gallbladder carcinomas.
Author:	Chang, Hee Jin\|Yoo, Byong Chul\|Kim, Sun Whe\|Lee, Byung Lan\|Kim, Woo Ho
PMID:	18158568

6.
Journal:	J Gastrointest Surg. 2008 Oct;12(10):1664-72; discussion 1672-3.
Title:	Loss of heterozygosity predicts poor survival after resection of pancreatic adenocarcinoma.
Author:	Franko, Jan\|Krasinskas, Alyssa M\|Nikiforova, Marina N\|Zarnescu, Narcis O\|Lee, Kenneth K W\|Hughes, Steven J\|Bartlett, David L\|Zeh, Herbert J 3rd\|Moser, A James
PMID:	18677542

7.
Journal:	Clin Cancer Res. 2009 Jan 15;15(2):660-7.
Title:	The expression of phospho-AKT, phospho-mTOR, and PTEN in extrahepatic cholangiocarcinoma.
Author:	Chung, Joon-Yong\|Hong, Seung-Mo\|Choi, Byeong Yeob\|Cho, Hyungjun\|Yu, Eunsil\|Hewitt, Stephen M
PMID:	19147772

8.
Journal:	Gastroenterology. 2011 Jun;140(7):2084-94.
Title:	Microsomal prostaglandin E synthase-1 inhibits PTEN and promotes experimental cholangiocarcinogenesis and tumor progression.
Author:	Lu, Dongdong\|Han, Chang\|Wu, Tong
PMID:	21354147

9.
Journal:	Br J Cancer. 2011 Apr 12;104(8):1313-8.
Title:	CpG-island methylation study of liver fluke-related cholangiocarcinoma.
Author:	Sriraksa, R\|Zeller, C\|El-Bahrawy, M A\|Dai, W\|Daduang, J\|Jearanaikoon, P\|Chau-In, S\|Brown, R\|Limpaiboon, T
PMID:	21448164

10.
Journal:	Pathol Res Pract. 2011 Aug 15;207(8):472-8.
Title:	Overexpression of EZH2 and loss of expression of PTEN is associated with invasion, metastasis, and poor progression of gallbladder adenocarcinoma.
Author:	Liu, Dong-Cai\|Yang, Zhu-Lin
PMID:	21719208

11.
Journal:	Genome Med. 2012 Jul 4;4(7):56.
Title:	Cancer of the ampulla of Vater: analysis of the whole genome sequence exposes a potential therapeutic vulnerability.
Author:	Demeure, Michael J\|Craig, David W\|Sinari, Shripad\|Moses, Tracy M\|Christoforides, Alexis\|Dinh, Jennifer\|Izatt, Tyler\|Aldrich, Jessica\|Decker, Ardis\|Baker, Angela\|Cherni, Irene\|Watanabe, April\|Koep, Lawrence\|Lake, Douglas\|Hostetter, Galen\|Trent, Jeffrey M\|V
PMID:	22762308

12.
Journal:	Chin Med Sci J. 2012 Jun;27(2):65-72.
Title:	PTEN and PDCD4 are bona fide targets of microRNA-21 in human cholangiocarcinoma.
Author:	Liu, Chang-zheng\|Liu, Wei\|Zheng, Yi\|Su, Jin-mei\|Li, Jing-jing\|Yu, Lan\|He, Xiao-dong\|Chen, Song-sen
PMID:	22770403

13.
Journal:	Oncologist. 2012;17(1):72-9.
Title:	Frequent mutation of isocitrate dehydrogenase (IDH)1 and IDH2 in cholangiocarcinoma identified through broad-based tumor genotyping.
Author:	Borger, Darrell R\|Tanabe, Kenneth K\|Fan, Kenneth C\|Lopez, Hector U\|Fantin, Valeria R\|Straley, Kimberly S\|Schenkein, David P\|Hezel, Aram F\|Ancukiewicz, Marek\|Liebman, Hannah M\|Kwak, Eunice L\|Clark, Jeffrey W\|Ryan, David P\|Deshpande, Vikram\|Dias-Santagata,
PMID:	22180306

14.
Journal:	Mod Pathol. 2012 Jan;25(1):131-9.
Title:	The expression of phospho-AKT1 and phospho-MTOR is associated with a favorable prognosis independent of PTEN expression in intrahepatic cholangiocarcinomas.
Author:	Lee, Dakeun\|Do, In-Gu\|Choi, Kyusam\|Sung, Chang Ohk\|Jang, Kee-Taek\|Choi, Dongwook\|Heo, Jin Seok\|Choi, Seoung Ho\|Kim, Jongmin\|Park, Jin Young\|Cha, Hyung Jin\|Joh, Jae-Won\|Choi, Kwan Yong\|Kim, Dae Shick
PMID:	21874010

15.
Journal:	Mol Carcinog. 2013 Apr;52(4):286-96.
Title:	Ars2 is overexpressed in human cholangiocarcinomas and its depletion increases PTEN and PDCD4 by decreasing microRNA-21.
Author:	He, Qian\|Cai, Lei\|Shuai, Ling\|Li, Dajiang\|Wang, Cheng\|Liu, Yongkang\|Li, Xiaowu\|Li, Zhihua\|Wang, Shuguang
PMID:	22213145

16.
Journal:	Gastroenterology. 2013 May;144(5):1055-65.
Title:	Akt and mTORC1 have different roles during liver tumorigenesis in mice.
Author:	Kenerson, Heidi L\|Yeh, Matthew M\|Kazami, Machiko\|Jiang, Xiuyun\|Riehle, Kimberly J\|McIntyre, Rebecca L\|Park, James O\|Kwon, Steve\|Campbell, Jean S\|Yeung, Raymond S
PMID:	23376645

17.
Journal:	J Pathol. 2013 Jun;230(2):165-73.
Title:	PTEN loss and KRAS activation cooperate in murine biliary tract malignancies.
Author:	Marsh, Victoria\|Davies, Emma J\|Williams, Geraint T\|Clarke, Alan R
PMID:	23483557

18.
Journal:	Tumour Biol. 2013 Dec;34(6):3637-48.
Title:	Increased activation of PI3K/AKT signaling pathway is associated with cholangiocarcinoma metastasis and PI3K/mTOR inhibition presents a possible therapeutic strategy.
Author:	Yothaisong, Supak\|Dokduang, Hasaya\|Techasen, Anchalee\|Namwat, Nisana\|Yongvanit, Puangrat\|Bhudhisawasdi, Vajarabhongsa\|Puapairoj, Anucha\|Riggins, Gregory J\|Loilome, Watcharin
PMID:	23832540

19.
Journal:	Nat Rev Gastroenterol Hepatol. 2013 Nov;10(11):656-65.
Title:	NAFLD, NASH and liver cancer.
Author:	Michelotti, Gregory A\|Machado, Mariana V\|Diehl, Anna Mae
PMID:	24080776

20.
Journal:	Eur Surg Res. 2013;51(3-4):108-17.
Title:	Role of aquaporin-5 in gallbladder carcinoma.
Author:	Sekine, S\|Shimada, Y\|Nagata, T\|Sawada, S\|Yoshioka, I\|Matsui, K\|Moriyama, M\|Omura, T\|Osawa, S\|Shibuya, K\|Hashimoto, I\|Watanabe, T\|Hojo, S\|Hori, R\|Okumura, T\|Yoshida, T\|Tsukada, K
PMID:	24217644

21.
Journal:	Ann Surg Oncol. 2014 Nov;21(12):3827-34.
Title:	Genomic profiling of intrahepatic cholangiocarcinoma: refining prognosis and identifying therapeutic targets.
Author:	Zhu, Andrew X\|Borger, Darrell R\|Kim, Yuhree\|Cosgrove, David\|Ejaz, Aslam\|Alexandrescu, Sorin\|Groeschl, Ryan Thomas\|Deshpande, Vikram\|Lindberg, James M\|Ferrone, Cristina\|Sempoux, Christine\|Yau, Thomas\|Poon, Ronnie\|Popescu, Irinel\|Bauer, Todd W\|Gamblin, T Cl
PMID:	24889489

22.
Journal:	Nat Commun. 2014 Dec 15;5:5696.
Title:	Mutational landscape of intrahepatic cholangiocarcinoma.
Author:	Zou, Shanshan\|Li, Jiarui\|Zhou, Huabang\|Frech, Christian\|Jiang, Xiaolan\|Chu, Jeffrey S C\|Zhao, Xinyin\|Li, Yuqiong\|Li, Qiaomei\|Wang, Hui\|Hu, Jingyi\|Kong, Guanyi\|Wu, Mengchao\|Ding, Chuanfan\|Chen, Nansheng\|Hu, Heping
PMID:	25526346

23.
Journal:	Am J Pathol. 2014 Oct;184(10):2828-39.
Title:	miR-17-92 cluster promotes cholangiocarcinoma growth: evidence for PTEN as downstream target and IL-6/Stat3 as upstream activator.
Author:	Zhu, Hanqing\|Han, Chang\|Lu, Dongdong\|Wu, Tong
PMID:	25239565

24.
Journal:	Oncotarget. 2014 May 15;5(9):2372-89.
Title:	Antitumor activity of the combination of an HSP90 inhibitor and a PI3K/mTOR dual inhibitor against cholangiocarcinoma.
Author:	Chen, Ming-Huang\|Chiang, Kun-Chun\|Cheng, Chi-Tung\|Huang, Shih-Chiang\|Chen, Yeng-Yang\|Chen, Tsung-Wen\|Yeh, Ta-Sen\|Jan, Yi-Yin\|Wang, Hsi-Ming\|Weng, Jiang-Jie\|Chang, Peter Mu-Hsin\|Liu, Chun-Yu\|Li, Chung-Pin\|Chao, Yee\|Chen, Ming-Han\|Huang, Chi-Ying F\|Yeh, Chu
PMID:	24796583

25.
Journal:	Oncologist. 2014 Mar;19(3):235-42.
Title:	New routes to targeted therapy of intrahepatic cholangiocarcinomas revealed by next-generation sequencing.
Author:	Ross, Jeffrey S\|Wang, Kai\|Gay, Laurie\|Al-Rohil, Rami\|Rand, Janne V\|Jones, David M\|Lee, Hwa J\|Sheehan, Christine E\|Otto, Geoff A\|Palmer, Gary\|Yelensky, Roman\|Lipson, Doron\|Morosini, Deborah\|Hawryluk, Matthew\|Catenacci, Daniel V T\|Miller, Vincent A\|Churi, C
PMID:	24563076

26.
Journal:	Mod Pathol. 2014 May;27(5):665-74.
Title:	Epidermal growth factor receptor signaling pathway is frequently altered in ampullary carcinoma at protein and genetic levels.
Author:	Mikhitarian, Kaidi\|Pollen, Maressa\|Zhao, Zhiguo\|Shyr, Yu\|Merchant, Nipun B\|Parikh, Alexander\|Revetta, Frank\|Washington, M Kay\|Vnencak-Jones, Cindy\|Shi, Chanjuan
PMID:	24186143

27.
Journal:	Mod Pathol. 2014 May;27(5):731-9.
Title:	High throughput molecular profiling reveals differential mutation patterns in intrahepatic cholangiocarcinomas arising in chronic advanced liver diseases.
Author:	Jang, Sejin\|Chun, Sung-Min\|Hong, Seoung-Mo\|Sung, Chang Ohk\|Park, Hosub\|Kang, Hyo Jeong\|Kim, Kyu-pyo\|Lee, Young Joo\|Yu, Eunsil
PMID:	24186137

28.
Journal:	Oncogene. 2014 Oct 16;33(42):4997-5005.
Title:	GRP78 as a regulator of liver steatosis and cancer progression mediated by loss of the tumor suppressor PTEN.
Author:	Chen, W-T\|Zhu, G\|Pfaffenbach, K\|Kanel, G\|Stiles, B\|Lee, A S
PMID:	24141775

29.
Journal:	Oncotarget. 2014 Feb 28;5(4):894-900.
Title:	Role of aberrant PI3K pathway activation in gallbladder tumorigenesis.
Author:	Lunardi, Andrea\|Webster, Kaitlyn A\|Papa, Antonella\|Padmani, Bhavik\|Clohessy, John G\|Bronson, Roderick T\|Pandolfi, Pier Paolo
PMID:	24658595

30.
Journal:	Chem Biol Drug Des. 2015 Oct;86(4):656-62.
Title:	Downregulation of TPTE2P1 Inhibits Migration and Invasion of Gallbladder Cancer Cells.
Author:	Lv, Wenjie\|Wang, Lei\|Lu, Jianhua\|Mu, Jiasheng\|Liu, Yingbin\|Dong, Ping
PMID:	25676706

31.
Journal:	Cancer Res. 2015 May 1;75(9):1859-67.
Title:	miR-21 Inhibition Reduces Liver Fibrosis and Prevents Tumor Development by Inducing Apoptosis of CD24+ Progenitor Cells.
Author:	Zhang, Jing\|Jiao, Jingjing\|Cermelli, Silvia\|Muir, Kyle\|Jung, Kwang Hwa\|Zou, Ruhai\|Rashid, Asif\|Gagea, Mihai\|Zabludoff, Sonya\|Kalluri, Raghu\|Beretta, Laura
PMID:	25769721

32.
Journal:	Oncotarget. 2015 Mar 20;6(8):5932-46.
Title:	MiR-21 promotes intrahepatic cholangiocarcinoma proliferation and growth in vitro and in vivo by targeting PTPN14 and PTEN.
Author:	Wang, Li-Juan\|He, Chen-Chen\|Sui, Xin\|Cai, Meng-Jiao\|Zhou, Cong-Ya\|Ma, Jin-Lu\|Wu, Lei\|Wang, Hao\|Han, Su-Xia\|Zhu, Qing
PMID:	25803229

33.
Journal:	Diagn Pathol. 2015 Aug 21;10:148.
Title:	Inactivation of tumor suppressor gene pten in early and advanced gallbladder cancer.
Author:	Roa, Ivan\|de Toro, Gonzalo\|Fernandez, Fernanda\|Game, Anakaren\|Munoz, Sergio\|de Aretxabala, Xabier\|Javle, Milind
PMID:	26294099

34.
Journal:	PLoS One. 2015 Oct 26;10(10):e0141168.
Title:	miR-221 Promotes Epithelial-Mesenchymal Transition through Targeting PTEN and Forms a Positive Feedback Loop with beta-catenin/c-Jun Signaling Pathway in Extra-Hepatic Cholangiocarcinoma.
Author:	Li, Jianguo\|Yao, Lei\|Li, Guodong\|Ma, Donglai\|Sun, Chen\|Gao, Shuang\|Zhang, Ping\|Gao, Feng
PMID:	26501139

35.
Journal:	Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):13982-7.
Title:	CRISPR/Cas9 somatic multiplex-mutagenesis for high-throughput functional cancer genomics in mice.
Author:	Weber, Julia\|Ollinger, Rupert\|Friedrich, Mathias\|Ehmer, Ursula\|Barenboim, Maxim\|Steiger, Katja\|Heid, Irina\|Mueller, Sebastian\|Maresch, Roman\|Engleitner, Thomas\|Gross, Nina\|Geumann, Ulf\|Fu, Beiyuan\|Segler, Angela\|Yuan, Detian\|Lange, Sebastian\|Strong, Alexa
PMID:	26508638

36.
Journal:	Cancer Genet. 2015 Dec;208(12):587-94.
Title:	Effects of PTEN gene alteration in patients with gallbladder cancer.
Author:	Ali, Asgar\|Mishra, Pramod Kumar\|Sharma, Sadhana\|Arora, Asit\|Saluja, Sundeep Singh
PMID:	26586294

37.
Journal:	Oncotarget. 2016 Apr 5;7(14):17751-9.
Title:	CD133 promotes gallbladder carcinoma cell migration through activating Akt phosphorylation.
Author:	Li, Chen\|Wang, Cong\|Xing, Yang\|Zhen, Jiaojiao\|Ai, Zhilong
PMID:	26910892

38.
Journal:	Onco Targets Ther. 2016 Aug 24;9:5297-305.
Title:	Knockdown of Sall4 inhibits intrahepatic cholangiocarcinoma cell migration and invasion in ICC-9810 cells.
Author:	Zhu, Lei\|Huang, Feizhou\|Deng, Gang\|Nie, Wanpin\|Huang, Wei\|Xu, Hongbo\|Zheng, Shaopeng\|Yi, Zhongjie\|Wan, Tao
PMID:	27601921

39.
Journal:	Sci Rep. 2016 Apr 1;6:23899.
Title:	A novel mouse model of intrahepatic cholangiocarcinoma induced by liver-specific Kras activation and Pten deletion.
Author:	Ikenoue, Tsuneo\|Terakado, Yumi\|Nakagawa, Hayato\|Hikiba, Yohko\|Fujii, Tomoaki\|Matsubara, Daisuke\|Noguchi, Rei\|Zhu, Chi\|Yamamoto, Keisuke\|Kudo, Yotaro\|Asaoka, Yoshinari\|Yamaguchi, Kiyoshi\|Ijichi, Hideaki\|Tateishi, Keisuke\|Fukushima, Noriyoshi\|Maeda, Shin\|Ko
PMID:	27032374

40.
Journal:	Gastroenterology. 2016 Mar;150(3):720-33.
Title:	Epithelial Transforming Growth Factor-beta Signaling Does Not Contribute to Liver Fibrosis but Protects Mice From Cholangiocarcinoma.
Author:	Mu, Xueru\|Pradere, Jean-Philippe\|Affo, Silvia\|Dapito, Dianne H\|Friedman, Richard\|Lefkovitch, Jay H\|Schwabe, Robert F
PMID:	26627606

41.
Journal:	J Clin Pathol. 2016 May;69(5):403-8.
Title:	Comprehensive genomic profiling of extrahepatic cholangiocarcinoma reveals a long tail of therapeutic targets.
Author:	Lee, Hwajeong\|Wang, Kai\|Johnson, Adrienne\|Jones, David M\|Ali, Siraj M\|Elvin, Julia A\|Yelensky, Roman\|Lipson, Doron\|Miller, Vincent A\|Stephens, Philip J\|Javle, Milind\|Ross, Jeffrey S
PMID:	26500333

42.
Journal:	Sci Rep. 2017 Jan 3;7:39567.
Title:	Corrigendum: A novel mouse model of intrahepatic cholangiocarcinoma induced by liver-specific Kras activation and Pten deletion.
Author:	Ikenoue, Tsuneo\|Terakado, Yumi\|Nakagawa, Hayato\|Hikiba, Yohko\|Fujii, Tomoaki\|Matsubara, Daisuke\|Noguchi, Rei\|Zhu, Chi\|Yamamoto, Keisuke\|Kudo, Yotaro\|Asaoka, Yoshinari\|Yamaguchi, Kiyoshi\|Ijichi, Hideaki\|Tateishi, Keisuke\|Fukushima, Noriyoshi\|Maeda, Shin\|Ko
PMID:	28045050

43.
Journal:	J Gastrointest Cancer. 2017 Mar;48(1):110-116.
Title:	Epigenetic Downregulation of PTEN in Gallbladder Cancer.
Author:	Tekcham, Dinesh Singh\|Gupta, Sanjeev\|Shrivastav, Braj Raj\|Tiwari, Pramod Kumar
PMID:	28124240

44.
Journal:	Oncotarget. 2017 Jul 18;8(29):47052-47063.
Title:	TROP2 promotes proliferation, migration and metastasis of gallbladder cancer cells by regulating PI3K/AKT pathway and inducing EMT.
Author:	Li, Xinxing\|Teng, Shifeng\|Zhang, Yanyan\|Zhang, Weigang\|Zhang, Xianwen\|Xu, Kai\|Yao, Houshan\|Yao, Jun\|Wang, Haolu\|Liang, Xiaowen\|Hu, Zhiqian
PMID:	28423362

45.
Journal:	Mol Oncol. 2017 Sep;11(9):1130-1142.
Title:	K-Ras mutation and amplification status is predictive of resistance and high basal pAKT is predictive of sensitivity to everolimus in biliary tract cancer cell lines.
Author:	Yeung, Yvonne\|Lau, David K\|Chionh, Fiona\|Tran, Hoanh\|Tse, Janson W T\|Weickhardt, Andrew J\|Nikfarjam, Mehrdad\|Scott, Andrew M\|Tebbutt, Niall C\|Mariadason, John M
PMID:	28544747

46.
Journal:	Pathol Res Pract. 2017 Aug;213(8):1010-1013.
Title:	Adenosquamous gallbladder carcinoma: Multigene hotspot mutational profiling reveals a monoclonal origin of the two components.
Author:	Galuppini, Francesca\|Salmaso, Roberta\|Valentini, Elisa\|Lanza, Cristiano\|Maretto, Isacco\|Nitti, Donato\|Rugge, Massimo\|Fassan, Matteo
PMID:	28698100

47.
Journal:	Cytotechnology. 2018 Feb;70(1):83-94.
Title:	Oxymatrine induces apoptosis and inhibits invasion in Gallbladder carcinoma via PTEN/PI3K/AKT pathway.
Author:	Qian, Liqiang\|Li, Xiaqin\|Ye, Penghui\|Wang, Gang\|Dai, Wei\|Liu, Yan\|Gao, Quangen\|Shen, Genhai
PMID:	29170841

48.
Journal:	Am J Cancer Res. 2018 Jan 1;8(1):2-15. eCollection 2018.
Title:	Genotyping and mRNA profiling reveal actionable molecular targets in biliary tract cancers.
Author:	Papadopoulou, Kyriaki\|Murray, Samuel\|Manousou, Kyriaki\|Tikas, Ioannis\|Dervenis, Christos\|Sgouros, Joseph\|Rontogianni, Dimitra\|Lakis, Sotirios\|Bobos, Mattheos\|Poulios, Christos\|Pervana, Stavroula\|Lazaridis, Georgios\|Fountzilas, George\|Kotoula, Vassiliki
PMID:	29416916

49.
Journal:	Cancer Lett. 2018 May 1;421:161-169.
Title:	Combination of Kras activation and PTEN deletion contributes to murine hepatopancreatic ductal malignancy.
Author:	Lin, Yun-Kai\|Fang, Zheng\|Jiang, Tian-Yi\|Wan, Zheng-Hua\|Pan, Yu-Fei\|Ma, Yun-Han\|Shi, Yuan-Yuan\|Tan, Ye-Xiong\|Dong, Li-Wei\|Zhang, Yong-Jie\|Wang, Hong-Yang
PMID:	29452147

50.
Journal:	Sci Rep. 2018 May 8;8(1):7119.
Title:	Genetic alterations analysis in prognostic stratified groups identified TP53 and ARID1A as poor clinical performance markers in intrahepatic cholangiocarcinoma.
Author:	Simbolo, Michele\|Vicentini, Caterina\|Ruzzenente, Andrea\|Brunelli, Matteo\|Conci, Simone\|Fassan, Matteo\|Mafficini, Andrea\|Rusev, Borislav\|Corbo, Vincenzo\|Capelli, Paola\|Bria, Emilio\|Pedron, Serena\|Turri, Giona\|Lawlor, Rita T\|Tortora, Giampaolo\|Bassi, Claudi
PMID:	29740198

51.
Journal:	Invest New Drugs. 2018 May 22. pii: 10.1007/s10637-018-0600-2.
Title:	Phase 1b investigation of the MEK inhibitor binimetinib in patients with advanced or metastatic biliary tract cancer.
Author:	Finn, R S\|Ahn, D H\|Javle, M M\|Tan, B R Jr\|Weekes, C D\|Bendell, J C\|Patnaik, A\|Khan, G N\|Laheru, D\|Chavira, R\|Christy-Bittel, J\|Barrett, E\|Sawyer, M B\|Bekaii-Saab, Tanios S
PMID:	29785570

52.
Journal:	Cancer Res Treat. 2018 Oct 1. pii: crt.2018.375.
Title:	Jab1 Silencing Inhibits Proliferation and Sensitizes to Cisplatin in Biliary Tract Cancer.
Author:	Nam, Ah-Rong\|Kim, Ji-Won\|Park, Ji Eun\|Bang, Ju-Hee\|Jin, Mei Hua\|Oh, Do-Youn\|Bang, Yung-Jue
PMID:	30282449

53.
Journal:	Hepatology. 2018 Oct 9.
Title:	The chemosensory function of primary cilia regulates cholangiocyte migration, invasion and tumor growth.
Author:	Mansini, Adrian P\|Peixoto, Estanislao\|Jin, Sujeong\|Richard, Seth\|Gradilone, Sergio A
PMID:	30299561