Primary Site >> Stomach Cancer

Gene >> PTCH1

Journal: Carcinogenesis. 1999 Nov;20(11):2189-92.
Title: A novel sensitive method to detect frameshift mutations in exonic repeat sequences of cancer-related genes.
Author: Mironov, N|Jansen, L A|Zhu, W B|Aguelon, A M|Reguer, G|Yamasaki, H
PMID: 10545425
Journal: Am J Med Genet A. 2003 Nov 1;122A(4):303-14.
Title: Molecular dimensions of gastrointestinal tumors: some thoughts for digestion.
Author: Cohen, M Michael Jr
PMID: 14518068
Journal: Int J Oncol. 2004 Dec;25(6):1875-80.
Title: KIF27 is one of orthologs for Drosophila Costal-2.
Author: Katoh, Yuriko|Katoh, Masaru
PMID: 15547729
Journal: Int J Oncol. 2005 Feb;26(2):545-9.
Title: Identification and characterization of rat Desert hedgehog and Indian hedgehog genes in silico.
Author: Katoh, Yuriko|Katoh, Masaru
PMID: 15645142
Journal: Cancer Biol Ther. 2005 Oct;4(10):1050-4. Epub 2005 Oct 18.
Title: Hedgehog signaling pathway and gastric cancer.
Author: Katoh, Yuriko|Katoh, Masaru
PMID: 16258256
Journal: Gastroenterology. 2006 Jul;131(1):14-29.
Title: Hedgehog signal activation in gastric pit cell and in diffuse-type gastric cancer.
Author: Fukaya, Masahide|Isohata, Noriyuki|Ohta, Hiroyuki|Aoyagi, Kazuhiko|Ochiya, Takahiro|Saeki, Norihisa|Yanagihara, Kazuyoshi|Nakanishi, Yukihiro|Taniguchi, Hirokazu|Sakamoto, Hiromi|Shimoda, Tadakazu|Nimura, Yuji|Yoshida, Teruhiko|Sasaki, Hiroki
PMID: 16831586
Journal: Int J Mol Med. 2006 Dec;18(6):1019-23.
Title: Hedgehog signaling pathway and gastrointestinal stem cell signaling network (review).
Author: Katoh, Yuriko|Katoh, Masaru
PMID: 17089004
Journal: Br J Cancer. 2007 Jun 18;96(12):1855-61.
Title: De-regulation of the sonic hedgehog pathway in the InsGas mouse model of gastric carcinogenesis.
Author: El-Zaatari, M|Tobias, A|Grabowska, A M|Kumari, R|Scotting, P J|Kaye, P|Atherton, J|Clarke, P A|Powe, D G|Watson, S A
PMID: 17505514
Journal: Cancer Biol Ther. 2007 Jun;6(6):832-9. Epub 2007 Mar 26.
Title: Dysregulation of stem cell signaling network due to germline mutation, SNP, Helicobacter pylori infection, epigenetic change and genetic alteration in gastric cancer.
Author: Katoh, Masaru
PMID: 17568183
Journal: Mol Carcinog. 2009 Aug;48(8):703-12.
Title: Regulation of the hedgehog signaling by the mitogen-activated protein kinase cascade in gastric cancer.
Author: Seto, Motoko|Ohta, Miki|Asaoka, Yoshinari|Ikenoue, Tsuneo|Tada, Motohisa|Miyabayashi, Koji|Mohri, Dai|Tanaka, Yasuo|Ijichi, Hideaki|Tateishi, Keisuke|Kanai, Fumihiko|Kawabe, Takao|Omata, Masao
PMID: 19142899
Journal: World J Gastroenterol. 2009 Aug 14;15(30):3799-806.
Title: Methylation of PTCH1a gene in a subset of gastric cancers.
Author: Du, Peng|Ye, Hai-Rong|Gao, Jun|Chen, Wei|Wang, Zhong-Chuan|Jiang, Hong-Hua|Xu, Ji|Zhang, Ji-We|Zhang, Jian-Cheng|Cui, Long
PMID: 19673023
Journal: Curr Mol Med. 2009 Sep;9(7):873-86.
Title: Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation.
Author: Katoh, Y|Katoh, M
PMID: 19860666
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2009 Nov;12(6):603-6.
Title: [Hedgehog signaling pathway activates in gastric carcinoma and promotes the proliferation through GLI1 in MKN28 cell].
Author: Li, Xiao-wei|Li, Jian-fang|Qu, Ying|Cai, Qu|Ji, Jun|Nie, Hui|Chen, Xue-hua|Zhu, Zheng-gang|Liu, Bing-ya
PMID: 19921574
Journal: J Surg Oncol. 2010 Oct 1;102(5):454-61.
Title: Identification of novel gastric cancer-associated CNVs by integrated analysis of microarray.
Author: Park, Chan-Hee|Rha, Sun-Young|Jeung, Hei-Cheul|Kang, Seung-Hui|Ki, Dong-Hyuk|Lee, Won-Suk|Noh, Sung-Hoon|Chung, Hyun-Cheol
PMID: 20872948
Journal: ANZ J Surg. 2011 Jun;81(6):440-5.
Title: The Hedgehog signalling pathway and its prognostic impact in human gliomas.
Author: Li, Qiaoyu|Zhang, Yan|Zhan, Hongfeng|Yuan, Zhicheng|Lu, Peisong|Zhan, Liping|Xu, Wenlin
PMID: 22295347
Journal: Oncol Lett. 2011 Nov;2(6):1291-1295.
Title: HSulf-1 suppresses cell growth and down-regulates Hedgehog signaling in human gastric cancer cells.
Author: Ma, Hui-Yan|Zhang, Fang|Li, Jie|Mo, Min-Li|Chen, Zhao|Liu, Lili|Zhou, Hai-Meng|Sheng, Qing
PMID: 22848304
Journal: J Cancer Res Clin Oncol. 2011 Nov;137(11):1679-86.
Title: Identification of CD44+CD24+ gastric cancer stem cells.
Author: Zhang, Chaojun|Li, Chenwei|He, Fengtian|Cai, Yujiao|Yang, Hua
PMID: 21882047
Journal: PLoS One. 2011 Mar 4;6(3):e17687.
Title: Sonic hedgehog pathway is essential for maintenance of cancer stem-like cells in human gastric cancer.
Author: Song, Zhou|Yue, Wen|Wei, Bo|Wang, Ning|Li, Tao|Guan, Lidong|Shi, Shuangshuang|Zeng, Quan|Pei, Xuetao|Chen, Lin
PMID: 21394208
Journal: Dig Surg. 2012;29(2):115-23.
Title: Activation of the sonic hedgehog pathway and its prognostic impact in patients with gastric cancer.
Author: Saze, Zenichiro|Terashima, Masanori|Kogure, Michihiko|Ohsuka, Fumihiko|Suzuki, Hiroyuki|Gotoh, Mitsukazu
PMID: 22456124
Journal: PLoS One. 2013;8(1):e54415.
Title: Mutations in the hedgehog pathway genes SMO and PTCH1 in human gastric tumors.
Author: Wang, Xi-De|Inzunza, Hector|Chang, Han|Qi, Zhenhao|Hu, Beihong|Malone, Daniel|Cogswell, John
PMID: 23349881
Journal: Target Oncol. 2013 Dec;8(4):271-80.
Title: Gastric cancer (GC) patients with hedgehog pathway activation: PTCH1 and GLI2 as independent prognostic factors.
Author: Lee, Su Jin|Do, In-Gu|Lee, Jeeyun|Kim, Kyoung-Mee|Jang, Jiryeon|Sohn, Insuk|Kang, Won Ki
PMID: 23371028
Journal: Exp Ther Med. 2013 Dec;6(6):1365-1368.
Title: Detection and analysis of the methylation status of PTCH1 gene involved in the hedgehog signaling pathway in a human gastric cancer cell line.
Author: Zuo, Yun|Song, Yu
PMID: 24255663
Journal: Arch Iran Med. 2014 Apr;17(4):286-92.
Title: Cancers of the upper gastro-intestinal tract: a review of somatic mutation distributions.
Author: Abedi-Ardekani, Behnoush|Hainaut, Pierre
PMID: 24724606
Journal: Am J Physiol Gastrointest Liver Physiol. 2014 Jun 15;306(12):G1075-88.
Title: Mesenchymal stem cells induce epithelial proliferation within the inflamed stomach.
Author: Donnelly, Jessica M|Engevik, Amy|Feng, Rui|Xiao, Chang|Boivin, Gregory P|Li, Jing|Houghton, JeanMarie|Zavros, Yana
PMID: 24789207
Journal: Oncol Lett. 2014 Aug;8(2):679-682.
Title: Role of PTCH1 gene methylation in gastric carcinogenesis.
Author: Zuo, Yun|Song, Yu|Zhang, Min|Xu, Zhen|Qian, Xiaolan
PMID: 25013484
Journal: Mol Med Rep. 2014 Nov;10(5):2563-7.
Title: Effect of resveratrol on proliferation and apoptosis of human pancreatic cancer MIA PaCa-2 cells may involve inhibition of the Hedgehog signaling pathway.
Author: Qin, Yong|Ma, Zhenhua|Dang, Xiaoyan|Li, Wei|Ma, Qingyong
PMID: 25190613
Journal: Cancer Res. 2016 Apr 1;76(7):1714-23.
Title: Genomic Landscape of Somatic Alterations in Esophageal Squamous Cell Carcinoma and Gastric Cancer.
Author: Hu, Nan|Kadota, Mitsutaka|Liu, Huaitian|Abnet, Christian C|Su, Hua|Wu, Hailong|Freedman, Neal D|Yang, Howard H|Wang, Chaoyu|Yan, Chunhua|Wang, Lemin|Gere, Sheryl|Hutchinson, Amy|Song, Guohong|Wang, Yuan|Ding, Ti|Qiao, You-Lin|Koshiol, Jill|Dawsey, Sanford
PMID: 26857264
Journal: World J Stem Cells. 2016 Nov 26;8(11):384-395.
Title: Gene expression and pathway analysis of CTNNB1 in cancer and stem cells.
Author: Tanabe, Shihori|Kawabata, Takeshi|Aoyagi, Kazuhiko|Yokozaki, Hiroshi|Sasaki, Hiroki
PMID: 27928465
Journal: Oncotarget. 2017 Apr 18;8(16):27412-27427.
Title: GLI1-mediated regulation of side population is responsible for drug resistance in gastric cancer.
Author: Yu, Beiqin|Gu, Dongsheng|Zhang, Xiaoli|Li, Jianfang|Liu, Bingya|Xie, Jingwu
PMID: 28404967
Journal: Digestion. 2017;96(2):81-91.
Title: Distinct Involvement of the Sonic Hedgehog Signaling Pathway in Gastric Adenocarcinoma of Fundic Gland Type and Conventional Gastric Adenocarcinoma.
Author: Tajima, Yuzuru|Murakami, Takashi|Saito, Tsuyoshi|Hiromoto, Takafumi|Akazawa, Yoichi|Sasahara, Noriko|Mitomi, Hiroyuki|Yao, Takashi|Watanabe, Sumio
PMID: 28738329
Journal: Cell Physiol Biochem. 2017;42(6):2242-2254.
Title: Exosomes Derived from Human Bone Marrow Mesenchymal Stem Cells Promote Tumor Growth Through Hedgehog Signaling Pathway.
Author: Qi, Jin|Zhou, Yali|Jiao, Zuoyi|Wang, Xu|Zhao, Yang|Li, Yangbin|Chen, Huijuan|Yang, Luxi|Zhu, Hongwen|Li, Yumin
PMID: 28817816
Journal: Am J Surg Pathol. 2018 Apr;42(4):553-560.
Title: A Distinct Malignant Epithelioid Neoplasm With GLI1 Gene Rearrangements, Frequent S100 Protein Expression, and Metastatic Potential: Expanding the Spectrum of Pathologic Entities With ACTB/MALAT1/PTCH1-GLI1 Fusions.
Author: Antonescu, Cristina R|Agaram, Narasimhan P|Sung, Yun-Shao|Zhang, Lei|Swanson, David|Dickson, Brendan C
PMID: 29309307