Primary Site >> Stomach Cancer

Gene >> PTCH1

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Ref: A novel sensitive method to detect frameshift mutations in exonic repeat sequences of cancer-related genes.
PMID: 10545425
Ref: Molecular dimensions of gastrointestinal tumors: some thoughts for digestion.
PMID: 14518068
Ref: KIF27 is one of orthologs for Drosophila Costal-2.
PMID: 15547729
Ref: Identification and characterization of rat Desert hedgehog and Indian hedgehog genes in silico.
PMID: 15645142
Ref: Hedgehog signaling pathway and gastric cancer.
PMID: 16258256
Ref: Hedgehog signal activation in gastric pit cell and in diffuse-type gastric cancer.
PMID: 16831586
Ref: Hedgehog signaling pathway and gastrointestinal stem cell signaling network (review).
PMID: 17089004
Ref: De-regulation of the sonic hedgehog pathway in the InsGas mouse model of gastric carcinogenesis.
PMID: 17505514
Ref: Dysregulation of stem cell signaling network due to germline mutation, SNP, Helicobacter pylori infection, epigenetic change and genetic alteration in gastric cancer.
PMID: 17568183
Ref: Regulation of the hedgehog signaling by the mitogen-activated protein kinase cascade in gastric cancer.
PMID: 19142899
Ref: Methylation of PTCH1a gene in a subset of gastric cancers.
PMID: 19673023
Ref: Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation.
PMID: 19860666
Ref: [Hedgehog signaling pathway activates in gastric carcinoma and promotes the proliferation through GLI1 in MKN28 cell].
PMID: 19921574
Ref: Identification of novel gastric cancer-associated CNVs by integrated analysis of microarray.
PMID: 20872948
Ref: Sonic hedgehog pathway is essential for maintenance of cancer stem-like cells in human gastric cancer.
PMID: 21394208
Ref: Identification of CD44+CD24+ gastric cancer stem cells.
PMID: 21882047
Ref: The Hedgehog signalling pathway and its prognostic impact in human gliomas.
PMID: 22295347
Ref: HSulf-1 suppresses cell growth and down-regulates Hedgehog signaling in human gastric cancer cells.
PMID: 22848304
Ref: Activation of the sonic hedgehog pathway and its prognostic impact in patients with gastric cancer.
PMID: 22456124
Ref: Mutations in the hedgehog pathway genes SMO and PTCH1 in human gastric tumors.
PMID: 23349881
Ref: Gastric cancer (GC) patients with hedgehog pathway activation: PTCH1 and GLI2 as independent prognostic factors.
PMID: 23371028
Ref: Detection and analysis of the methylation status of PTCH1 gene involved in the hedgehog signaling pathway in a human gastric cancer cell line.
PMID: 24255663
Ref: Cancers of the upper gastro-intestinal tract: a review of somatic mutation distributions.
PMID: 24724606
Ref: Mesenchymal stem cells induce epithelial proliferation within the inflamed stomach.
PMID: 24789207
Ref: Role of PTCH1 gene methylation in gastric carcinogenesis.
PMID: 25013484
Ref: Effect of resveratrol on proliferation and apoptosis of human pancreatic cancer MIA PaCa-2 cells may involve inhibition of the Hedgehog signaling pathway.
PMID: 25190613
Ref: Genomic Landscape of Somatic Alterations in Esophageal Squamous Cell Carcinoma and Gastric Cancer.
PMID: 26857264
Ref: Gene expression and pathway analysis of CTNNB1 in cancer and stem cells.
PMID: 27928465
Ref: GLI1-mediated regulation of side population is responsible for drug resistance in gastric cancer.
PMID: 28404967
Ref: Distinct Involvement of the Sonic Hedgehog Signaling Pathway in Gastric Adenocarcinoma of Fundic Gland Type and Conventional Gastric Adenocarcinoma.
PMID: 28738329
Ref: Exosomes Derived from Human Bone Marrow Mesenchymal Stem Cells Promote Tumor Growth Through Hedgehog Signaling Pathway.
PMID: 28817816
Ref: A Distinct Malignant Epithelioid Neoplasm With GLI1 Gene Rearrangements, Frequent S100 Protein Expression, and Metastatic Potential: Expanding the Spectrum of Pathologic Entities With ACTB/MALAT1/PTCH1-GLI1 Fusions.
PMID: 29309307