Primary Site >> Colorectal Cancer
Gene >> PTCH1
| 1. | |||||||||||
| Journal: | Cancer Res. 1997 Jun 15;57(12):2369-72. | ||||||||||
| Title: | Mutations of the PATCHED gene in several types of sporadic extracutaneous tumors. | ||||||||||
| Author: | Xie, J|Johnson, R L|Zhang, X|Bare, J W|Waldman, F M|Cogen, P H|Menon, A G|Warren, R S|Chen, L C|Scott, M P|Epstein, E H Jr | ||||||||||
| PMID: | 9192811 | ||||||||||
| 2. | |||||||||||
| Journal: | Eur J Cancer. 1999 May;35(5):711-3. | ||||||||||
| Title: | The patched/hedgehog/smoothened signalling pathway in human breast cancer: no evidence for H133Y SHH, PTCH and SMO mutations. | ||||||||||
| Author: | Vorechovsky, I|Benediktsson, K P|Toftgard, R | ||||||||||
| PMID: | 10505029 | ||||||||||
| 3. | |||||||||||
| Journal: | Carcinogenesis. 1999 Nov;20(11):2189-92. | ||||||||||
| Title: | A novel sensitive method to detect frameshift mutations in exonic repeat sequences of cancer-related genes. | ||||||||||
| Author: | Mironov, N|Jansen, L A|Zhu, W B|Aguelon, A M|Reguer, G|Yamasaki, H | ||||||||||
| PMID: | 10545425 | ||||||||||
| 4. | |||||||||||
| Journal: | Am J Med Genet A. 2003 Nov 1;122A(4):303-14. | ||||||||||
| Title: | Molecular dimensions of gastrointestinal tumors: some thoughts for digestion. | ||||||||||
| Author: | Cohen, M Michael Jr | ||||||||||
| PMID: | 14518068 | ||||||||||
| 5. | |||||||||||
| Journal: | J Pathol. 2004 Aug;203(4):909-17. | ||||||||||
| Title: | Expression of Sonic hedgehog pathway genes is altered in colonic neoplasia. | ||||||||||
| Author: | Oniscu, Anca|James, Roberta M|Morris, Robert G|Bader, Scott|Malcomson, Roger D G|Harrison, David J | ||||||||||
| PMID: | 15258993 | ||||||||||
| 6. | |||||||||||
| Journal: | Int J Oncol. 2005 Feb;26(2):545-9. | ||||||||||
| Title: | Identification and characterization of rat Desert hedgehog and Indian hedgehog genes in silico. | ||||||||||
| Author: | Katoh, Yuriko|Katoh, Masaru | ||||||||||
| PMID: | 15645142 | ||||||||||
| 7. | |||||||||||
| Journal: | Int J Mol Med. 2006 Dec;18(6):1019-23. | ||||||||||
| Title: | Hedgehog signaling pathway and gastrointestinal stem cell signaling network (review). | ||||||||||
| Author: | Katoh, Yuriko|Katoh, Masaru | ||||||||||
| PMID: | 17089004 | ||||||||||
| 8. | |||||||||||
| Journal: | World J Gastroenterol. 2007 Mar 21;13(11):1659-65. | ||||||||||
| Title: | Sonic hedgehog-Gli1 pathway in colorectal adenocarcinomas. | ||||||||||
| Author: | Bian, Yue-Hong|Huang, Shu-Hong|Yang, Ling|Ma, Xiao-Li|Xie, Jing-Wu|Zhang, Hong-Wei | ||||||||||
| PMID: | 17461467 | ||||||||||
| 9. | |||||||||||
| Journal: | Int J Cancer. 2007 Dec 15;121(12):2622-7. | ||||||||||
| Title: | Hedgehog signaling pathway is inactive in colorectal cancer cell lines. | ||||||||||
| Author: | Chatel, Guillaume|Ganeff, Corine|Boussif, Naima|Delacroix, Laurence|Briquet, Alexandra|Nolens, Gregory|Winkler, Rosita | ||||||||||
| PMID: | 17683069 | ||||||||||
| 10. | |||||||||||
| Journal: | Virchows Arch. 2009 Apr;454(4):369-79. | ||||||||||
| Title: | Hedgehog signaling is involved in differentiation of normal colonic tissue rather than in tumor proliferation. | ||||||||||
| Author: | Alinger, Beate|Kiesslich, Tobias|Datz, Christian|Aberger, Fritz|Strasser, Felix|Berr, Frieder|Dietze, Otto|Kaserer, Klaus|Hauser-Kronberger, Cornelia | ||||||||||
| PMID: | 19280222 | ||||||||||
| 11. | |||||||||||
| Journal: | J Gastroenterol. 2009;44(11):1113-7. | ||||||||||
| Title: | Sonic hedgehog relates to colorectal carcinogenesis. | ||||||||||
| Author: | Yoshikawa, Kozo|Shimada, Mitsuo|Miyamoto, Hidenori|Higashijima, Jun|Miyatani, Tomohiko|Nishioka, Masanori|Kurita, Nobuhiro|Iwata, Takashi|Uehara, Hisanori | ||||||||||
| PMID: | 19662327 | ||||||||||
| 12. | |||||||||||
| Journal: | Ups J Med Sci. 2010 Aug;115(3):169-75. | ||||||||||
| Title: | PTCH1, a receptor of Hedgehog signaling pathway, is correlated with metastatic potential of colorectal cancer. | ||||||||||
| Author: | You, Sihong|Zhou, Jiannong|Chen, Senqing|Zhou, Ping|Lv, Jinghuan|Han, Xiao|Sun, Yujie | ||||||||||
| PMID: | 20230186 | ||||||||||
| 13. | |||||||||||
| Journal: | Hepatogastroenterology. 2011 Sep-Oct;58(110-111):1511-8. | ||||||||||
| Title: | Cyclopamine blocked the growth of colorectal cancer SW116 cells by modulating some target genes of Gli1 in vitro. | ||||||||||
| Author: | Wu, Jian-Ye|Xu, Xuan-Fu|Xu, Ling|Niu, Pei-Qin|Wang, Feng|Hu, Guo-Yong|Wang, Xing-Peng|Guo, Chuan-Yong | ||||||||||
| PMID: | 21940310 | ||||||||||
| 14. | |||||||||||
| Journal: | Oncotarget. 2011 Aug;2(8):638-45. | ||||||||||
| Title: | The GLI genes as the molecular switch in disrupting Hedgehog signaling in colon cancer. | ||||||||||
| Author: | Mazumdar, Tapati|DeVecchio, Jennifer|Agyeman, Akwasi|Shi, Ting|Houghton, Janet A | ||||||||||
| PMID: | 21860067 | ||||||||||
| 15. | |||||||||||
| Journal: | Mol Med Rep. 2011 Sep-Oct;4(5):873-7. | ||||||||||
| Title: | Differential expression profiles of the Hedgehog signaling pathway between microsatellite-stable and microsatellite-unstable colorectal cancers. | ||||||||||
| Author: | Hu, Xuguang|Lai, Daili|Chen, Wei|Zi, Shuming|Li, Jinming|Du, Peng|Wang, Zhongchuan|Huang, Shiyong|Long, Cui | ||||||||||
| PMID: | 21725600 | ||||||||||
| 16. | |||||||||||
| Journal: | Virchows Arch. 2011 Feb;458(2):213-9. | ||||||||||
| Title: | Downregulation of the hedgehog receptor PTCH1 in colorectal serrated adenocarcinomas is not caused by PTCH1 mutations. | ||||||||||
| Author: | Stefanius, Karoliina|Kantola, Tiina|Tuomisto, Anne|Vahteristo, Pia|Karttunen, Tuomo J|Aaltonen, Lauri A|Makinen, Markus J|Karhu, Auli | ||||||||||
| PMID: | 21234763 | ||||||||||
| 17. | |||||||||||
| Journal: | Br J Cancer. 2011 Sep 6;105(6):870-5. | ||||||||||
| Title: | A two-phase case-control study for colorectal cancer genetic susceptibility: candidate genes from chromosomal regions 9q22 and 3q22. | ||||||||||
| Author: | Abuli, A|Fernandez-Rozadilla, C|Giraldez, M D|Munoz, J|Gonzalo, V|Bessa, X|Bujanda, L|Rene, J M|Lanas, A|Garcia, A M|Salo, J|Arguello, L|Vilella, A|Carreno, R|Jover, R|Xicola, R M|Llor, X|Carvajal-Carmona, L|Tomlinson, I P M|Kerr, D J|Houlston, R S|Pique, | ||||||||||
| PMID: | 21811255 | ||||||||||
| 18. | |||||||||||
| Journal: | Anticancer Res. 2012 Mar;32(3):907-13. | ||||||||||
| Title: | Silencing of CCDC6 reduces the expression of 14-3-3sigma in colorectal carcinoma cells. | ||||||||||
| Author: | Thanasopoulou, Angeliki|Xanthopoulou, Alexandra G|Anagnostopoulos, Athanasios K|Konstantakou, Eumorphia G|Margaritis, Lukas H|Papassideri, Isidora S|Stravopodis, Dimitrios J|Tsangaris, George T|Anastasiadou, Ema | ||||||||||
| PMID: | 22399611 | ||||||||||
| 19. | |||||||||||
| Journal: | Asian Pac J Cancer Prev. 2012;13(8):4001-5. | ||||||||||
| Title: | Expression of smoothened protein in colon cancer and its prognostic value for postoperative liver metastasis. | ||||||||||
| Author: | Ding, Yin-Lu|Wang, Qi-San|Zhao, Wei-Min|Xiang, Lei | ||||||||||
| PMID: | 23098507 | ||||||||||
| 20. | |||||||||||
| Journal: | Int J Cancer. 2013 Jan 15;132(2):E18-25. | ||||||||||
| Title: | Aberrant methylation of the PTCH1 gene promoter region in aberrant crypt foci. | ||||||||||
| Author: | Peng, Liang|Hu, Jingjing|Li, Shujun|Wang, Zhongqiu|Xia, Bingqing|Jiang, Bo|Li, Bingsheng|Zhang, Yu|Wang, Jing|Wang, Xinying | ||||||||||
| PMID: | 22945423 | ||||||||||
| 21. | |||||||||||
| Journal: | J Dig Dis. 2013 Aug;14(8):417-24. | ||||||||||
| Title: | Aberrant expression of sonic hedgehog pathway in colon cancer and melanosis coli. | ||||||||||
| Author: | Wang, Zhong Chuan|Gao, Jun|Zi, Shu Ming|Yang, Ming|Du, Peng|Cui, Long | ||||||||||
| PMID: | 23551431 | ||||||||||
| 22. | |||||||||||
| Journal: | Oncotarget. 2013 Dec;4(12):2208-11. | ||||||||||
| Title: | A loss-of-function mutation in PTCH1 suggests a role for autocrine hedgehog signaling in colorectal tumorigenesis. | ||||||||||
| Author: | Chung, Jon H|Bunz, Fred | ||||||||||
| PMID: | 24368541 | ||||||||||
| 23. | |||||||||||
| Journal: | Oncol Lett. 2014 Nov;8(5):2203-2208. | ||||||||||
| Title: | Hedgehog-glioma-associated oncogene homolog-1 signaling in colon cancer cells and its role in the celecoxib-mediated anti-cancer effect. | ||||||||||
| Author: | Wang, Hongtao|Ke, Fei|Zheng, Jie | ||||||||||
| PMID: | 25295109 | ||||||||||
| 24. | |||||||||||
| Journal: | J Gastroenterol Hepatol. 2014 Jun;29(6):1192-9. | ||||||||||
| Title: | Distinct profile of HIF1alpha, PTCH, EphB2, or DNA repair protein expression and BRAF mutation in colorectal serrated adenoma. | ||||||||||
| Author: | Morimoto, Takashi|Mitomi, Hiroyuki|Saito, Tsuyoshi|Takahashi, Michiko|Murakami, Takashi|Sakamoto, Naoto|Yao, Takashi|Watanabe, Sumio | ||||||||||
| PMID: | 24612059 | ||||||||||
| 25. | |||||||||||
| Journal: | Cell Oncol (Dordr). 2016 Jun;39(3):243-52. | ||||||||||
| Title: | Biomarkers for the identification of precursor polyps of colorectal serrated adenocarcinomas. | ||||||||||
| Author: | Garcia-Solano, Jose|Garcia-Solano, Maria Eulalia|Torres-Moreno, Daniel|Carbonell, Pablo|Trujillo-Santos, Javier|Perez-Guillermo, Miguel|Conesa-Zamora, Pablo | ||||||||||
| PMID: | 26832730 | ||||||||||
| 26. | |||||||||||
| Journal: | Iran J Basic Med Sci. 2016 Nov;19(11):1171-1176. | ||||||||||
| Title: | The hedgehog/Gli-1 signaling pathways is involved in the inhibitory effect of resveratrol on human colorectal cancer HCT116 cells. | ||||||||||
| Author: | Du, Zhou|Zhou, Feng|Jia, Zengrong|Zheng, Beishi|Han, Shaoliang|Cheng, Jun|Zhu, Guanbao|Huang, Ping | ||||||||||
| PMID: | 27917272 | ||||||||||
| 27. | |||||||||||
| Journal: | Genome Med. 2017 May 24;9(1):46. | ||||||||||
| Title: | Multilevel genomics of colorectal cancers with microsatellite instability-clinical impact of JAK1 mutations and consensus molecular subtype 1. | ||||||||||
| Author: | Sveen, Anita|Johannessen, Bjarne|Tengs, Torstein|Danielsen, Stine A|Eilertsen, Ina A|Lind, Guro E|Berg, Kaja C G|Leithe, Edward|Meza-Zepeda, Leonardo A|Domingo, Enric|Myklebost, Ola|Kerr, David|Tomlinson, Ian|Nesbakken, Arild|Skotheim, Rolf I|Lothe, Ragnh | ||||||||||
| PMID: | 28539123 | ||||||||||
| 28. | |||||||||||
| Journal: | Oncol Res. 2017 May 24;25(5):681-689. | ||||||||||
| Title: | FOXR2 Promotes the Proliferation, Invasion, and Epithelial-Mesenchymal Transition in Human Colorectal Cancer Cells. | ||||||||||
| Author: | Lu, Sheng-Qiang|Qiu, Yan|Dai, Wei-Jie|Zhang, Xiao-Yu | ||||||||||
| PMID: | 28548041 | ||||||||||
| 29. | |||||||||||
| Journal: | Genes Chromosomes Cancer. 2017 Nov;56(11):769-787. | ||||||||||
| Title: | The co-regulatory networks of tumor suppressor genes, oncogenes, and miRNAs in colorectal cancer. | ||||||||||
| Author: | Slattery, Martha L|Herrick, Jennifer S|Mullany, Lila E|Samowitz, Wade S|Sevens, John R|Sakoda, Lori|Wolff, Roger K | ||||||||||
| PMID: | 28675510 | ||||||||||
| 30. | |||||||||||
| Journal: | Cell Rep. 2017 Dec 5;21(10):2813-2828. | ||||||||||
| Title: | Non-Canonical Hedgehog Signaling Is a Positive Regulator of the WNT Pathway and Is Required for the Survival of Colon Cancer Stem Cells. | ||||||||||
| Author: | Regan, Joseph L|Schumacher, Dirk|Staudte, Stephanie|Steffen, Andreas|Haybaeck, Johannes|Keilholz, Ulrich|Schweiger, Caroline|Golob-Schwarzl, Nicole|Mumberg, Dominik|Henderson, David|Lehrach, Hans|Regenbrecht, Christian R A|Schafer, Reinhold|Lange, Martin | ||||||||||
| PMID: | 29212028 | ||||||||||
| 31. | |||||||||||
| Journal: | Front Pharmacol. 2018 Feb 2;8:956. | ||||||||||
| Title: | SMO Inhibition Modulates Cellular Plasticity and Invasiveness in Colorectal Cancer. | ||||||||||
| Author: | Magistri, Paolo|Battistelli, Cecilia|Strippoli, Raffaele|Petrucciani, Niccolo|Pellinen, Teijo|Rossi, Lucia|Mangogna, Livia|Aurello, Paolo|D'Angelo, Francesco|Tripodi, Marco|Ramacciato, Giovanni|Nigri, Giuseppe | ||||||||||
| PMID: | 29456503 | ||||||||||
| 32. | |||||||||||
| Journal: | Cancer. 2018 Mar 1;124(5):1070-1082. | ||||||||||
| Title: | A mutational comparison of adult and adolescent and young adult (AYA) colon cancer. | ||||||||||
| Author: | Tricoli, James V|Boardman, Lisa A|Patidar, Rajesh|Sindiri, Sivasish|Jang, Jin S|Walsh, William D|McGregor, Paul M 3rd|Camalier, Corinne E|Mehaffey, Michele G|Furman, Wayne L|Bahrami, Armita|Williams, P Mickey|Lih, Chih-Jian|Conley, Barbara A|Khan, Javed | ||||||||||
| PMID: | 29194591 | ||||||||||
| 33. | |||||||||||
| Journal: | Oncotarget. 2018 Jan 29;9(13):11170-11179. | ||||||||||
| Title: | Two novel colorectal cancer risk loci in the region on chromosome 9q22.32. | ||||||||||
| Author: | Thutkawkorapin, Jessada|Mahdessian, Hovsep|Barber, Tom|Picelli, Simone|von Holst, Susanna|Lundin, Johanna|Valle, Laura|Kontham, Vinaykumar|Liu, Tao|Nilsson, Daniel|Jiao, Xiang|Lindblom, Annika | ||||||||||
| PMID: | 29541405 | ||||||||||