Primary Site >> Colorectal Cancer
Gene >> PRRT2
| 1. | |||||||||||
| Journal: | Arch Surg. 1987 Dec;122(12):1475-8. | ||||||||||
| Title: | Studies on protein kinase C and colon carcinogenesis. | ||||||||||
| Author: | Guillem, J G|O'Brian, C A|Fitzer, C J|Johnson, M D|Forde, K A|LoGerfo, P|Weinstein, I B | ||||||||||
| PMID: | 3689124 | ||||||||||
| 2. | |||||||||||
| Journal: | Experientia. 1989 Jun 15;45(6):588-91. | ||||||||||
| Title: | Changes in glycosaminoglycan sulfation and protein kinase C subcellular distribution during differentiation of the human colon tumor cell line Caco-2. | ||||||||||
| Author: | Levy, P|Cherqui, G|Robert, A|Wicek, D|Picard, J | ||||||||||
| PMID: | 2737267 | ||||||||||
| 3. | |||||||||||
| Journal: | Mol Cell Biol. 1990 Sep;10(9):4650-7. | ||||||||||
| Title: | Overexpression of protein kinase C in HT29 colon cancer cells causes growth inhibition and tumor suppression. | ||||||||||
| Author: | Choi, P M|Tchou-Wong, K M|Weinstein, I B | ||||||||||
| PMID: | 2388620 | ||||||||||
| 4. | |||||||||||
| Journal: | Dis Colon Rectum. 1993 Oct;36(10):913-21. | ||||||||||
| Title: | Decreased levels of protein kinase C enzyme activity and protein kinase C mRNA in primary colon tumors. | ||||||||||
| Author: | Levy, M F|Pocsidio, J|Guillem, J G|Forde, K|LoGerfo, P|Weinstein, I B | ||||||||||
| PMID: | 8404381 | ||||||||||
| 5. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 1993 Jun 15;193(2):759-63. | ||||||||||
| Title: | Effect of staurosporine on suppression of heat shock gene expression and thermotolerance development in HT-29 cells. | ||||||||||
| Author: | Kim, S H|Kim, J H|Erdos, G|Lee, Y J | ||||||||||
| PMID: | 8512574 | ||||||||||
| 6. | |||||||||||
| Journal: | Dig Dis Sci. 1994 Mar;39(3):458-63. | ||||||||||
| Title: | Protein kinase C activity as a potential marker for colorectal neoplasia. | ||||||||||
| Author: | McGarrity, T J|Peiffer, L P | ||||||||||
| PMID: | 8131680 | ||||||||||
| 7. | |||||||||||
| Journal: | FEBS Lett. 1994 May 16;344(2-3):161-5. | ||||||||||
| Title: | Antipeptide antibodies directed against the C-terminus of protein kinase C zeta (PKC zeta) react with a Ca(2+)- and TPA-sensitive PKC in HT-29 human intestinal epithelial cells. | ||||||||||
| Author: | Batlle, E|Fabre, M|Garcia de Herreros, A | ||||||||||
| PMID: | 8187876 | ||||||||||
| 8. | |||||||||||
| Journal: | Biochem Pharmacol. 1994 Jul 19;48(2):375-81. | ||||||||||
| Title: | Evidence that protein kinase C-alpha activation is a critical event in phorbol ester-induced multiple drug resistance in human colon cancer cells. | ||||||||||
| Author: | Gravitt, K R|Ward, N E|Fan, D|Skibber, J M|Levin, B|O'Brian, C A | ||||||||||
| PMID: | 8053934 | ||||||||||
| 9. | |||||||||||
| Journal: | Mol Carcinog. 1994 Dec;11(4):197-203. | ||||||||||
| Title: | Expression of multiple isoforms of protein kinase C in normal human colon mucosa and colon tumors and decreased levels of protein kinase C beta and eta mRNAs in the tumors. | ||||||||||
| Author: | Doi, S|Goldstein, D|Hug, H|Weinstein, I B | ||||||||||
| PMID: | 7999261 | ||||||||||
| 10. | |||||||||||
| Journal: | Cell Growth Differ. 1994 Sep;5(9):967-73. | ||||||||||
| Title: | The enterocyte-like differentiation of the Caco-2 tumor cell line strongly correlates with responsiveness to cAMP and activation of kinase A pathway. | ||||||||||
| Author: | Pignata, S|Maggini, L|Zarrilli, R|Rea, A|Acquaviva, A M | ||||||||||
| PMID: | 7819134 | ||||||||||
| 11. | |||||||||||
| Journal: | Biochem Pharmacol. 1994 Nov 29;48(11):2057-63. | ||||||||||
| Title: | Effect of 1-(5-isoquinolinesulfonyl)-2-methylpiperazine (H-7) on HSP70 and HSP28 gene expression and thermotolerance development in human colon carcinoma cells. | ||||||||||
| Author: | Lee, Y J|Berns, C M|Erdos, G|Borrelli, M J|Ahn, C H|Corry, P M | ||||||||||
| PMID: | 7802695 | ||||||||||
| 12. | |||||||||||
| Journal: | Cancer Metastasis Rev. 1994 Dec;13(3-4):411-31. | ||||||||||
| Title: | Regulation of protein kinase C and role in cancer biology. | ||||||||||
| Author: | Blobe, G C|Obeid, L M|Hannun, Y A | ||||||||||
| PMID: | 7712599 | ||||||||||
| 13. | |||||||||||
| Journal: | J Surg Res. 1995 Feb;58(2):233-9. | ||||||||||
| Title: | Differential expression of protein kinase C isoforms in human colorectal cancers. | ||||||||||
| Author: | Kuranami, M|Powell, C T|Hug, H|Zeng, Z|Cohen, A M|Guillem, J G | ||||||||||
| PMID: | 7861778 | ||||||||||
| 14. | |||||||||||
| Journal: | Prog Clin Biol Res. 1995;391:117-20. | ||||||||||
| Title: | The tumor promoter receptor protein kinase C: a novel target for chemoprevention and therapy of human colon cancer. | ||||||||||
| Author: | O'Brian, C A|Ward, N E|Gravitt, K R|Gupta, K P | ||||||||||
| PMID: | 8532710 | ||||||||||
| 15. | |||||||||||
| Journal: | Anticancer Res. 1996 Jan-Feb;16(1):395-9. | ||||||||||
| Title: | MAPK activity is down-regulated in human colon adenocarcinoma: correlation with PKC activity. | ||||||||||
| Author: | Attar, B M|Atten, M J|Holian, O | ||||||||||
| PMID: | 8615643 | ||||||||||
| 16. | |||||||||||
| Journal: | Prog Clin Biol Res. 1996;395:223-34. | ||||||||||
| Title: | Diet intervention for modifying cancer risk. | ||||||||||
| Author: | Birt, D F|Pelling, J C|Nair, S|Lepley, D | ||||||||||
| PMID: | 8895992 | ||||||||||
| 17. | |||||||||||
| Journal: | Cancer Lett. 1996 Oct 1;107(1):83-9. | ||||||||||
| Title: | Staurosporine inhibits the proliferation, alters the cell cycle distribution and induces apoptosis in HT-29 human colon adenocarcinoma cells. | ||||||||||
| Author: | Qiao, L|Koutsos, M|Tsai, L L|Kozoni, V|Guzman, J|Shiff, S J|Rigas, B | ||||||||||
| PMID: | 8913270 | ||||||||||
| 18. | |||||||||||
| Journal: | Gastroenterology. 1996 Jun;110(6):1753-9. | ||||||||||
| Title: | Protein kinase C tissue localization in human colonic tumors suggests a role for adenoma growth control. | ||||||||||
| Author: | Kahl-Rainer, P|Sedivy, R|Marian, B | ||||||||||
| PMID: | 8964400 | ||||||||||
| 19. | |||||||||||
| Journal: | Jpn J Hum Genet. 1997 Sep;42(3):409-16. | ||||||||||
| Title: | Suppression of serum-induced c-jun expression by activated Ki-ras in human colon cancer cells. | ||||||||||
| Author: | Furuse, M|Shirasawa, S|Okumura, K|Ohmori, M|Sasazuki, T | ||||||||||
| PMID: | 12503187 | ||||||||||
| 20. | |||||||||||
| Journal: | Invest New Drugs. 1997;15(4):311-8. | ||||||||||
| Title: | Potent induction of human colon cancer cell uptake of chemotherapeutic drugs by N-myristoylated protein kinase C-alpha (PKC-alpha) pseudosubstrate peptides through a P-glycoprotein-independent mechanism. | ||||||||||
| Author: | Bergman, P J|Gravitt, K R|Ward, N E|Beltran, P|Gupta, K P|O'Brian, C A | ||||||||||
| PMID: | 9547673 | ||||||||||
| 21. | |||||||||||
| Journal: | Cancer Res. 2001 Feb 15;61(4):1375-81. | ||||||||||
| Title: | Elevated protein kinase C betaII is an early promotive event in colon carcinogenesis. | ||||||||||
| Author: | Gokmen-Polar, Y|Murray, N R|Velasco, M A|Gatalica, Z|Fields, A P | ||||||||||
| PMID: | 11245437 | ||||||||||
| 22. | |||||||||||
| Journal: | Int J Cancer. 2001 Jul 15;93(2):179-84. | ||||||||||
| Title: | Expression of protein kinase C beta1 confers resistance to TNFalpha- and paclitaxel-induced apoptosis in HT-29 colon carcinoma cells. | ||||||||||
| Author: | Cesaro, P|Raiteri, E|Demoz, M|Castino, R|Baccino, F M|Bonelli, G|Isidoro, C | ||||||||||
| PMID: | 11410863 | ||||||||||
| 23. | |||||||||||
| Journal: | Mol Carcinog. 2002 Sep;35(1):21-8. | ||||||||||
| Title: | Involvement of both extracellular signal-regulated kinase and c-jun N-terminal kinase pathways in the 12-O-tetradecanoylphorbol-13-acetate-induced upregulation of p21(Cip1) in colon cancer cells. | ||||||||||
| Author: | Lin, Shyr-Yi|Liang, Yu-Chih|Ho, Yuan-Soon|Tsai, Shu-Huei|Pan, Shiann|Lee, Wen-Sen | ||||||||||
| PMID: | 12203364 | ||||||||||
| 24. | |||||||||||
| Journal: | J Biol Chem. 2003 Nov 28;278(48):47937-45. Epub 2003 Sep 9. | ||||||||||
| Title: | Defective human MutY phosphorylation exists in colorectal cancer cell lines with wild-type MutY alleles. | ||||||||||
| Author: | Parker, Antony R|O'Meally, Robert N|Sahin, Fikret|Su, Gloria H|Racke, Frederick K|Nelson, William G|DeWeese, Theodore L|Eshleman, James R | ||||||||||
| PMID: | 12966098 | ||||||||||
| 25. | |||||||||||
| Journal: | J Biol Chem. 2004 Nov 5;279(45):47379-90. Epub 2004 Aug 10. | ||||||||||
| Title: | Autocrine transforming growth factor alpha regulates cell adhesion by multiple signaling via specific phosphorylation sites of p70S6 kinase in colon cancer cells. | ||||||||||
| Author: | Sawhney, Rajinder S|Cookson, Michelle M|Sharma, Bhavya|Hauser, Jennie|Brattain, Michael G | ||||||||||
| PMID: | 15304500 | ||||||||||
| 26. | |||||||||||
| Journal: | J Biol Chem. 2004 Dec 24;279(52):54185-92. Epub 2004 Oct 15. | ||||||||||
| Title: | Protein kinase C activation promotes the internalization of the human cationic amino acid transporter hCAT-1. A new regulatory mechanism for hCAT-1 activity. | ||||||||||
| Author: | Rotmann, Alexander|Strand, Dennis|Martine, Ursula|Closs, Ellen I | ||||||||||
| PMID: | 15491978 | ||||||||||
| 27. | |||||||||||
| Journal: | Cell Prolif. 2004 Dec;37(6):427-41. | ||||||||||
| Title: | Extracellular pressure stimulates colon cancer cell proliferation via a mechanism requiring PKC and tyrosine kinase signals. | ||||||||||
| Author: | Walsh, M F|Woo, R K-Y|Gomez, R|Basson, M D | ||||||||||
| PMID: | 15548175 | ||||||||||
| 28. | |||||||||||
| Journal: | Zhonghua Wei Chang Wai Ke Za Zhi. 2006 Jul;9(4):331-4. | ||||||||||
| Title: | [Target lethal effect of recombinant soluble Fas coupled with protein kinase C inhibitor on colorectal carcinoma cells]. | ||||||||||
| Author: | Chen, Guang|Li, Shi-yong|Yu, Bo|An, Ping | ||||||||||
| PMID: | 16886117 | ||||||||||
| 29. | |||||||||||
| Journal: | Br J Cancer. 2008 Dec 2;99(11):1808-15. | ||||||||||
| Title: | Antiproliferative activity of PEP005, a novel ingenol angelate that modulates PKC functions, alone and in combination with cytotoxic agents in human colon cancer cells. | ||||||||||
| Author: | Benhadji, K A|Serova, M|Ghoul, A|Cvitkovic, E|Le Tourneau, C|Ogbourne, S M|Lokiec, F|Calvo, F|Hammel, P|Faivre, S|Raymond, E | ||||||||||
| PMID: | 19034280 | ||||||||||
| 30. | |||||||||||
| Journal: | Int J Colorectal Dis. 2009 Jun;24(6):641-5. | ||||||||||
| Title: | Protein kinase C-beta II (PKC-beta II) expression in patients with colorectal cancer. | ||||||||||
| Author: | Spindler, Karen-Lise Garm|Lindebjerg, Jan|Lahn, Michael|Kjaer-Frifeldt, Sanne|Jakobsen, Anders | ||||||||||
| PMID: | 19277684 | ||||||||||
| 31. | |||||||||||
| Journal: | Lab Invest. 2009 Aug;89(8):948-59. | ||||||||||
| Title: | Non-histone nuclear factor HMGB1 is phosphorylated and secreted in colon cancers. | ||||||||||
| Author: | Kang, Hyun Ju|Lee, Hanna|Choi, Hee-Jung|Youn, Ju Ho|Shin, Jeon-Soo|Ahn, Yeong Hee|Yoo, Jong Shin|Paik, Young-Ki|Kim, Hoguen | ||||||||||
| PMID: | 19506549 | ||||||||||
| 32. | |||||||||||
| Journal: | BMC Cancer. 2011 Oct 2;11:421. | ||||||||||
| Title: | Role of protein kinase C and epidermal growth factor receptor signalling in growth stimulation by neurotensin in colon carcinoma cells. | ||||||||||
| Author: | Muller, Kristin M|Tveteraas, Ingun H|Aasrum, Monica|Odegard, John|Dawood, Mona|Dajani, Olav|Christoffersen, Thoralf|Sandnes, Dagny L | ||||||||||
| PMID: | 21961726 | ||||||||||
| 33. | |||||||||||
| Journal: | Biol Open. 2013 Oct 8;2(11):1264-9. | ||||||||||
| Title: | Par-complex aPKC and Par3 cross-talk with innate immunity NF-kappaB pathway in epithelial cells. | ||||||||||
| Author: | Forteza, Radia|Wald, Flavia A|Mashukova, Anastasia|Kozhekbaeva, Zhanna|Salas, Pedro J | ||||||||||
| PMID: | 24244864 | ||||||||||
| 34. | |||||||||||
| Journal: | Cell. 2015 Jan 29;160(3):489-502. | ||||||||||
| Title: | Cancer-associated protein kinase C mutations reveal kinase's role as tumor suppressor. | ||||||||||
| Author: | Antal, Corina E|Hudson, Andrew M|Kang, Emily|Zanca, Ciro|Wirth, Christopher|Stephenson, Natalie L|Trotter, Eleanor W|Gallegos, Lisa L|Miller, Crispin J|Furnari, Frank B|Hunter, Tony|Brognard, John|Newton, Alexandra C | ||||||||||
| PMID: | 25619690 | ||||||||||
| 35. | |||||||||||
| Journal: | Biochimie. 2016 Feb;121:131-9. | ||||||||||
| Title: | Regulation of protein kinase CK2 catalytic activity by protein kinase C and phospholipase D2. | ||||||||||
| Author: | Lee, Young-Hoon|Park, Jeong-Woo|Bae, Young-Seuk | ||||||||||
| PMID: | 26703243 | ||||||||||
| 36. | |||||||||||
| Journal: | Oncotarget. 2017 Jan 24;8(4):6043-6056. | ||||||||||
| Title: | A mononucleotide repeat in PRRT2 is an important, frequent target of mismatch repair deficiency in cancer. | ||||||||||
| Author: | Alves, Ines Teles|Cano, David|Bottcher, Rene|van der Korput, Hetty|Dinjens, Winand|Jenster, Guido|Trapman, Jan | ||||||||||
| PMID: | 27907910 | ||||||||||
| 37. | |||||||||||
| Journal: | Histopathology. 2017 Oct;71(4):529-542. | ||||||||||
| Title: | Clinicopathological characteristics of KIT and protein kinase C-delta expression in adenoid cystic carcinoma: comparison with chromophobe renal cell carcinoma and gastrointestinal stromal tumour. | ||||||||||
| Author: | Park, Cheol Keun|Kim, Won Kyu|Kim, Hoguen | ||||||||||
| PMID: | 28561935 | ||||||||||
| 38. | |||||||||||
| Journal: | Cell Death Dis. 2018 Jan 18;9(2):23. | ||||||||||
| Title: | Discovery of a small-molecule protein kinase Cdelta-selective activator with promising application in colon cancer therapy. | ||||||||||
| Author: | Bessa, Claudia|Soares, Joana|Raimundo, Liliana|Loureiro, Joana B|Gomes, Celia|Reis, Flavio|Soares, Miguel L|Santos, Daniel|Dureja, Chetna|Chaudhuri, Saumya R|Lopez-Haber, Cynthia|Kazanietz, Marcelo G|Goncalves, Jorge|Simoes, Maria F|Rijo, Patricia|Saraiva | ||||||||||
| PMID: | 29348560 | ||||||||||
| 39. | |||||||||||
| Journal: | Biochim Biophys Acta Mol Cell Res. 2018 Apr;1865(4):650-664. | ||||||||||
| Title: | Protein Kinase C-zeta stimulates colorectal cancer cell carcinogenesis via PKC-zeta/Rac1/Pak1/beta-Catenin signaling cascade. | ||||||||||
| Author: | Islam, S M Anisul|Patel, Rekha|Acevedo-Duncan, Mildred | ||||||||||
| PMID: | 29408512 | ||||||||||