Primary Site >> Colorectal Cancer
Gene >> PRKDC
| 1. | |||||||||||
| Journal: | Oncol Res. 1997;9(6-7):295-302. | ||||||||||
| Title: | Importance of glutathione and associated enzymes in drug response. | ||||||||||
| Author: | Shen, H|Kauvar, L|Tew, K D | ||||||||||
| PMID: | 9406235 | ||||||||||
| 2. | |||||||||||
| Journal: | Carcinogenesis. 2001 Sep;22(9):1551-5. | ||||||||||
| Title: | High susceptibility of Scid mice to colon carcinogenesis induced by azoxymethane indicates a possible caretaker role for DNA-dependent protein kinase. | ||||||||||
| Author: | Ochiai, M|Ubagai, T|Kawamori, T|Imai, H|Sugimura, T|Nakagama, H | ||||||||||
| PMID: | 11532879 | ||||||||||
| 3. | |||||||||||
| Journal: | Cancer Res. 2001 Dec 1;61(23):8381-4. | ||||||||||
| Title: | Decreased expression of DNA-dependent protein kinase, a DNA repair protein, during human colon carcinogenesis. | ||||||||||
| Author: | Rigas, B|Borgo, S|Elhosseiny, A|Balatsos, V|Manika, Z|Shinya, H|Kurihara, N|Go, M|Lipkin, M | ||||||||||
| PMID: | 11731412 | ||||||||||
| 4. | |||||||||||
| Journal: | Int J Radiat Biol. 2003 Jan;79(1):53-60. | ||||||||||
| Title: | Expression of the DNA-PK binding protein E4-34K fails to confer radiation sensitivity to mammalian cells. | ||||||||||
| Author: | Collis, S J|Ketner, G W|Hicks, J L|Nelson, W G|Demarzo, A M|Deweese, T L | ||||||||||
| PMID: | 12556331 | ||||||||||
| 5. | |||||||||||
| Journal: | Int J Oncol. 2004 Aug;25(2):461-8. | ||||||||||
| Title: | Up-regulation of DNA-dependent protein kinase activity and Sp1 in colorectal cancer. | ||||||||||
| Author: | Hosoi, Yoshio|Watanabe, Toshiaki|Nakagawa, Keiichi|Matsumoto, Yoshihisa|Enomoto, Atsushi|Morita, Akinori|Nagawa, Hirokazu|Suzuki, Norio | ||||||||||
| PMID: | 15254745 | ||||||||||
| 6. | |||||||||||
| Journal: | Cancer Res. 2007 Jan 15;67(2):634-42. | ||||||||||
| Title: | Adenovirus-mediated expression of a dominant negative Ku70 fragment radiosensitizes human tumor cells under aerobic and hypoxic conditions. | ||||||||||
| Author: | He, Fuqiu|Li, Ligeng|Kim, Dooha|Wen, Bixiu|Deng, Xuelong|Gutin, Philip H|Ling, Clifton C|Li, Gloria C | ||||||||||
| PMID: | 17234773 | ||||||||||
| 7. | |||||||||||
| Journal: | Oncogene. 2008 Aug 21;27(36):4888-99. | ||||||||||
| Title: | Truncation mutations abolish chromatin-associated activities of adenomatous polyposis coli. | ||||||||||
| Author: | Kouzmenko, A P|Takeyama, K|Kawasaki, Y|Akiyama, T|Kato, S | ||||||||||
| PMID: | 18454178 | ||||||||||
| 8. | |||||||||||
| Journal: | Zhonghua Yi Xue Za Zhi. 2008 Jul 29;88(29):2025-9. | ||||||||||
| Title: | [Clinicopathological significance of expressions of DNA dependent protein kinase catalytic subunit and P16 in colorectal carcinoma]. | ||||||||||
| Author: | Lu, Yang|Zhang, Hong-lin|Li, Ya-zhuo|Zhao, Po | ||||||||||
| PMID: | 19080428 | ||||||||||
| 9. | |||||||||||
| Journal: | PLoS One. 2009;4(2):e4388. | ||||||||||
| Title: | Five quantitative trait loci control radiation-induced adenoma multiplicity in Mom1R Apc Min/+ mice. | ||||||||||
| Author: | Elahi, Eiram|Suraweera, Nirosha|Volikos, Emmanouil|Haines, Jackie|Brown, Natalie|Davidson, Gerovie|Churchman, Mike|Ilyas, Mohammed|Tomlinson, Ian|Silver, Andrew | ||||||||||
| PMID: | 19194513 | ||||||||||
| 10. | |||||||||||
| Journal: | Int J Mol Med. 2010 Mar;25(3):321-9. | ||||||||||
| Title: | Expression profile of significant immortalization genes in colon cancer. | ||||||||||
| Author: | Witkowska, Agnieszka|Gumprecht, Janusz|Glogowska-Ligus, Joanna|Wystrychowski, Grzegorz|Owczarek, Aleksander|Stachowicz, Malgorzata|Bocianowska, Alina|Nowakowska-Zajdel, Ewa|Mazurek, Urszula | ||||||||||
| PMID: | 20127035 | ||||||||||
| 11. | |||||||||||
| Journal: | Int J Radiat Oncol Biol Phys. 2010 May 1;77(1):226-34. | ||||||||||
| Title: | Radiation-induced survivin nuclear accumulation is linked to DNA damage repair. | ||||||||||
| Author: | Capalbo, Gianni|Dittmann, Klaus|Weiss, Christian|Reichert, Sebastian|Hausmann, Eva|Rodel, Claus|Rodel, Franz | ||||||||||
| PMID: | 20394854 | ||||||||||
| 12. | |||||||||||
| Journal: | Int J Oncol. 2011 Aug;39(2):393-400. | ||||||||||
| Title: | Priming and potentiation of DNA damage response by fibronectin in human colon cancer cells and tumor-derived myofibroblasts. | ||||||||||
| Author: | De Wever, Olivier|Sobczak-Thepot, Joelle|Vercoutter-Edouart, Anne-Sophie|Michalski, Jean-Claude|Ouelaa-Benslama, Radia|Stupack, Dwayne G|Bracke, Marc|Wang, Jean Y J|Gespach, Christian|Emami, Shahin | ||||||||||
| PMID: | 21567080 | ||||||||||
| 13. | |||||||||||
| Journal: | Nucleic Acids Res. 2012 Apr;40(8):3456-69. | ||||||||||
| Title: | Cdx2 homeoprotein inhibits non-homologous end joining in colon cancer but not in leukemia cells. | ||||||||||
| Author: | Renouf, Benjamin|Soret, Christine|Saandi, Thoueiba|Delalande, Francois|Martin, Elisabeth|Vanier, Marie|Duluc, Isabelle|Gross, Isabelle|Freund, Jean-Noel|Domon-Dell, Claire | ||||||||||
| PMID: | 22189105 | ||||||||||
| 14. | |||||||||||
| Journal: | Transl Cancer Res. 2012 Jun;1(2):4-14. | ||||||||||
| Title: | Oncolytic virus-mediated tumor radiosensitization in mice through DNA-PKcs-specific shRNA. | ||||||||||
| Author: | Kon, Takashi|Zhang, Xiuwu|Huang, Qian|Yang, Zhonghui|Liu, Shanling|Yan, Bin|Li, Fang|Wang, He|Li, Chuan-Yuan | ||||||||||
| PMID: | 22924158 | ||||||||||
| 15. | |||||||||||
| Journal: | Mol Cancer Ther. 2012 Aug;11(8):1789-98. | ||||||||||
| Title: | Chemosensitization of cancer cells by KU-0060648, a dual inhibitor of DNA-PK and PI-3K. | ||||||||||
| Author: | Munck, Joanne M|Batey, Michael A|Zhao, Yan|Jenkins, Helen|Richardson, Caroline J|Cano, Celine|Tavecchio, Michele|Barbeau, Jody|Bardos, Julia|Cornell, Liam|Griffin, Roger J|Menear, Keith|Slade, Andrew|Thommes, Pia|Martin, Niall M B|Newell, David R|Smith, G | ||||||||||
| PMID: | 22576130 | ||||||||||
| 16. | |||||||||||
| Journal: | Invest New Drugs. 2012 Jun;30(3):1248-56. | ||||||||||
| Title: | Irinotecan and DNA-PKcs inhibitors synergize in killing of colon cancer cells. | ||||||||||
| Author: | Davidson, David|Coulombe, Yannick|Martinez-Marignac, Veronica L|Amrein, Lilian|Grenier, Jeremy|Hodkinson, Keira|Masson, Jean-Yves|Aloyz, Raquel|Panasci, Lawrence | ||||||||||
| PMID: | 21221710 | ||||||||||
| 17. | |||||||||||
| Journal: | Med Mol Morphol. 2013 Mar;46(1):14-9. | ||||||||||
| Title: | Identification of DNA-dependent protein kinase catalytic subunit as a novel interaction partner of lymphocyte enhancer factor 1. | ||||||||||
| Author: | Shimomura, Atsushi|Takasaki, Akihiko|Nomura, Ryuji|Hayashi, Nobuhiro|Senda, Takao | ||||||||||
| PMID: | 23325550 | ||||||||||
| 18. | |||||||||||
| Journal: | Cancer Lett. 2013 Aug 9;336(1):85-95. | ||||||||||
| Title: | Instability at the FRA8I common fragile site disrupts the genomic integrity of the KIAA0146, CEBPD and PRKDC genes in colorectal cancer. | ||||||||||
| Author: | Brueckner, Lena M|Hess, Elisa M|Schwab, Manfred|Savelyeva, Larissa | ||||||||||
| PMID: | 23603433 | ||||||||||
| 19. | |||||||||||
| Journal: | Tumour Biol. 2014 Apr;35(4):3525-34. | ||||||||||
| Title: | The influence of AKT isoforms on radiation sensitivity and DNA repair in colon cancer cell lines. | ||||||||||
| Author: | Sahlberg, Sara Haggblad|Gustafsson, Ann-Sofie|Pendekanti, Prathyusha N|Glimelius, Bengt|Stenerlow, Bo | ||||||||||
| PMID: | 24338765 | ||||||||||
| 20. | |||||||||||
| Journal: | Exp Anim. 2014;63(3):289-96. | ||||||||||
| Title: | Characterization of EBV-related lymphoproliferative lesions arising in donor lymphocytes of transplanted human tumor tissues in the NOG mouse. | ||||||||||
| Author: | Fujii, Etsuko|Kato, Atsuhiko|Chen, Yu Jau|Matsubara, Koichi|Ohnishi, Yasuyuki|Suzuki, Masami | ||||||||||
| PMID: | 25077758 | ||||||||||
| 21. | |||||||||||
| Journal: | Exp Anim. 2015;64(2):181-90. | ||||||||||
| Title: | The status of donor cancer tissues affects the fate of patient-derived colorectal cancer xenografts in NOG mice. | ||||||||||
| Author: | Fujii, Etsuko|Kato, Atsuhiko|Chen, Yu Jau|Matsubara, Koichi|Ohnishi, Yasuyuki|Suzuki, Masami | ||||||||||
| PMID: | 25740629 | ||||||||||
| 22. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2015 Oct 23;466(3):547-53. | ||||||||||
| Title: | DNA-PKcs interference sensitizes colorectal cancer cells to a mTOR kinase inhibitor WAY-600. | ||||||||||
| Author: | Wu, Ling|Zhang, Jiansheng|Wu, Huiguo|Han, Enkun | ||||||||||
| PMID: | 26381179 | ||||||||||
| 23. | |||||||||||
| Journal: | Gene. 2016 Jun 10;584(1):90-6. | ||||||||||
| Title: | Identification of PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide) as an essential gene for colorectal cancer (CRCs) cells. | ||||||||||
| Author: | Sun, Shangfeng|Cheng, Shuguang|Zhu, Yunxiao|Zhang, Peng|Liu, Ning|Xu, Tong|Sun, Chao|Lv, Yanfeng | ||||||||||
| PMID: | 26992638 | ||||||||||
| 24. | |||||||||||
| Journal: | Mol Biol Cell. 2017 Jan 1;28(1):192-200. | ||||||||||
| Title: | Chromatin association of XRCC5/6 in the absence of DNA damage depends on the XPE gene product DDB2. | ||||||||||
| Author: | Fantini, Damiano|Huang, Shuo|Asara, John M|Bagchi, Srilata|Raychaudhuri, Pradip | ||||||||||
| PMID: | 28035050 | ||||||||||
| 25. | |||||||||||
| Journal: | J Surg Res. 2018 Jul;227:158-167. | ||||||||||
| Title: | Using patient-derived xenograft models of colorectal liver metastases to predict chemosensitivity. | ||||||||||
| Author: | Brown, Kai M|Xue, Aiqun|Julovi, Sohel M|Gill, Anthony J|Pavlakis, Nick|Samra, Jaswinder S|Smith, Ross C|Hugh, Thomas J | ||||||||||
| PMID: | 29804848 | ||||||||||
| 26. | |||||||||||
| Journal: | Int J Cancer. 2018 Jul 10. | ||||||||||
| Title: | Copy number variation analysis and targeted NGS in 77 families with suspected Lynch syndrome reveals novel potential causative genes. | ||||||||||
| Author: | Kayser, Katrin|Degenhardt, Franziska|Holzapfel, Stefanie|Horpaopan, Sukanya|Peters, Sophia|Spier, Isabel|Morak, Monika|Vangala, Deepak|Rahner, Nils|von Knebel-Doeberitz, Magnus|Schackert, Hans K|Engel, Christoph|Buttner, Reinhard|Wijnen, Juul|Doerks, Tobi | ||||||||||
| PMID: | 29987844 | ||||||||||
| 27. | |||||||||||
| Journal: | Cell Death Dis. 2018 Sep 27;9(10):1009. | ||||||||||
| Title: | Keratin 80 promotes migration and invasion of colorectal carcinoma by interacting with PRKDC via activating the AKT pathway. | ||||||||||
| Author: | Li, Changcan|Liu, Xisheng|Liu, Yuan|Liu, Xueni|Wang, Rangrang|Liao, Jianhua|Wu, Shaohan|Fan, Junwei|Peng, Zhihai|Li, Bin|Wang, Zhaowen | ||||||||||
| PMID: | 30262880 | ||||||||||