Primary Site >> Stomach Cancer

Gene >> PRKCA

Journal: Biochem Soc Trans. 1993 May;21(2):192S.
Title: Protein kinase C alpha is the isoform responsible for inhibition of histamine H2 receptor mediated stimulation of adenylate cyclase in the human gastric cancer cell line HGT-1.
Author: McKenna, P|Williams, J M|Hanson, P J
PMID: 8359445
Journal: Inflamm Res. 1995 Feb;44(2):66-9.
Title: The alpha isoform of protein kinase C inhibits histamine-stimulated adenylate cyclase activity in a particulate fraction of the human gastric cancer cell line HGT-1.
Author: McKenna, J P|Williams, J M|Hanson, P J
PMID: 7544678
Journal: Shi Yan Sheng Wu Xue Bao. 1996 Sep;29(3):197-205.
Title: [Co-regulative effect of PKA-RII and PKC-alpha kinase subspecies on expression of c-myc and c-H-ras in human gastric cancer cells (MGC 80-3)].
Author: Wang, D S|Liang, Y Y|Peng, J
PMID: 9639807
Journal: Oncogene. 1999 Sep 30;18(40):5604-9.
Title: Protein kinase Calpha promotes apoptotic cell death in gastric cancer cells depending upon loss of anchorage.
Author: Okuda, H|Adachi, M|Miyazawa, M|Hinoda, Y|Imai, K
PMID: 10523838
Journal: Cancer Chemother Pharmacol. 2000;45(5):389-96.
Title: Selective inhibition of cyclooxygenase-2 enhances mitomycin-C-induced apoptosis.
Author: Hsueh, C T|Chiu, C F|Kelsen, D P|Schwartz, G K
PMID: 10803922
Journal: Biochem Pharmacol. 2001 Nov 15;62(10):1423-32.
Title: Resveratrol-induced inactivation of human gastric adenocarcinoma cells through a protein kinase C-mediated mechanism.
Author: Atten, M J|Attar, B M|Milson, T|Holian, O
PMID: 11709203
Journal: Zhonghua Zhong Liu Za Zhi. 2001 Mar;23(2):103-6.
Title: [Expression and function of protein kinase C-alpha and beta I isoenzymes in drug-resistant gastric cancer cells].
Author: Han, Y|Shi, Y|Li, L
PMID: 11783010
Journal: Zhonghua Yi Xue Za Zhi. 2001 Mar 25;81(6):328-31.
Title: [Alteration of subcellular distribution of protein kinase C isoforms in swelling-activated multi-drug-resistant gastric cancer cells and its significance].
Author: Han, Y|Shi, Y|Zhang, H
PMID: 11798893
Journal: Sci China C Life Sci. 2002 Jun;45(3):237-44.
Title: PKCalpha translocation from mitochondria to nucleus is closely related to induction of apoptosis in gastric cancer cells.
Author: Wu, Qiao|Liu, Su|Ding, Liang|Ye, Xiaofeng|Su, Wenjin
PMID: 18759046
Journal: World J Gastroenterol. 2003 Nov;9(11):2413-8.
Title: Roles of PLC-gamma2 and PKCalpha in TPA-induced apoptosis of gastric cancer cells.
Author: Zhang, Bing|Wu, Qiao|Ye, Xiao-Feng|Liu, Su|Lin, Xiao-Feng|Chen, Mu-Chuan
PMID: 14606067
Journal: Ai Zheng. 2004 Apr;23(4):396-400.
Title: [Effect of PKC inhibitor on P-gp expression and drug-resistance in MGC803 cells].
Author: Chen, Bo|Jin, Feng|Lu, Xiang-Lan|Wang, Ping-Ping|Liu, Yun-Peng|Wang, Shu-Bao
PMID: 15087026
Journal: Cancer Res. 2004 Aug 15;64(16):5787-94.
Title: Antisense targeting protein kinase C alpha and beta1 inhibits gastric carcinogenesis.
Author: Jiang, Xiao-Hua|Tu, Shui-Ping|Cui, Jian-Tao|Lin, Marie C M|Xia, Harry H X|Wong, Wai Man|Chan, Annie On-On|Yuen, Man Fung|Jiang, Shi-Hu|Lam, Shiu-Kum|Kung, Hsiang-Fu|Soh, Jae Won|Weinstein, I Bernard|Wong, Benjamin Chun-Yu
PMID: 15313921
Journal: Mol Pharmacol. 2004 Dec;66(6):1465-77.
Title: Induction of cyclooxygenase-2 overexpression in human gastric epithelial cells by Helicobacter pylori involves TLR2/TLR9 and c-Src-dependent nuclear factor-kappaB activation.
Author: Chang, Ya Jen|Wu, Ming Shiang|Lin, Jaw Town|Sheu, Bor Shyang|Muta, Tatsushi|Inoue, Hiroyasu|Chen, Ching-Chow
PMID: 15456896
Journal: J Surg Oncol. 2008 May 1;97(6):538-43.
Title: Overexpression of protein kinase Calpha mRNA may be an independent prognostic marker for gastric carcinoma.
Author: Lin, Kai-Yuan|Fang, Chia-Lang|Uen, Yih-Huei|Chang, Chun-Chao|Lou, Horng-Yuan|Hsieh, Ching-Ruey|Tiong, Cheng|Pan, Shiann|Chen, Sheng-Hsuan
PMID: 18314869
Journal: World J Gastroenterol. 2009 Mar 14;15(10):1259-63.
Title: Antisense expression of PKCalpha improved sensitivity of SGC7901/VCR cells to doxorubicin.
Author: Wu, Da-Long|Sui, Feng-Ying|Du, Cheng|Zhang, Cheng-Wen|Hui, Bin|Xu, Shui-Ling|Lu, Huan-Zhang|Song, Guo-Jie
PMID: 19291828
Journal: Cell Mol Biol Lett. 2010 Sep;15(3):377-94.
Title: 12-O-tetradecanoylphorbol-1, 3-acetate induces the negative regulation of protein kinase B by protein kinase Calpha during gastric cancer cell apoptosis.
Author: Zhang, Bing|Xia, Chun
PMID: 20428959
Journal: J Cell Biochem. 2011 Jul;112(7):1761-72.
Title: Transcriptional regulation of claudin-18 via specific protein kinase C signaling pathways and modification of DNA methylation in human pancreatic cancer cells.
Author: Ito, Tatsuya|Kojima, Takashi|Yamaguchi, Hiroshi|Kyuno, Daisuke|Kimura, Yasutoshi|Imamura, Masafumi|Takasawa, Akira|Murata, Masaki|Tanaka, Satoshi|Hirata, Koichi|Sawada, Norimasa
PMID: 21381080
Journal: PLoS One. 2013;8(2):e56675.
Title: Clinicopathological correlation and prognostic significance of protein kinase calpha overexpression in human gastric carcinoma.
Author: Lin, Shee-Chan|Chen, Wei-Yu|Lin, Kai-Yuan|Chen, Sheng-Hsuan|Chang, Chun-Chao|Lin, Sey-En|Fang, Chia-Lang
PMID: 23468872
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2013 Apr;33(4):559-62.
Title: [Expressions of COX-2, PKC-alpha and miR-101 in gastric cancer and their correlations].
Author: Sun, Haibing|Wei, Yongchang|Tu, Honglei|DU, Ning|Zhao, Yang|Hu, Lijuan|Ren, Hong
PMID: 23644120
Journal: PLoS One. 2013 Nov 15;8(11):e81702.
Title: Mycophenolic acid inhibits migration and invasion of gastric cancer cells via multiple molecular pathways.
Author: Dun, Boying|Sharma, Ashok|Teng, Yong|Liu, Haitao|Purohit, Sharad|Xu, Heng|Zeng, Lingwen|She, Jin-Xiong
PMID: 24260584
Journal: Mol Med Rep. 2014 Nov;10(5):2563-7.
Title: Effect of resveratrol on proliferation and apoptosis of human pancreatic cancer MIA PaCa-2 cells may involve inhibition of the Hedgehog signaling pathway.
Author: Qin, Yong|Ma, Zhenhua|Dang, Xiaoyan|Li, Wei|Ma, Qingyong
PMID: 25190613
Journal: PLoS One. 2014 Sep 24;9(9):e107830.
Title: The inhibitory effect of pseudolaric acid B on gastric cancer and multidrug resistance via Cox-2/PKC-alpha/P-gp pathway.
Author: Sun, Qian|Li, Yan
PMID: 25250794
Journal: Oncol Lett. 2015 Oct;10(4):1947-1952.
Title: Role of annexin A6 in cancer.
Author: Qi, Houbao|Liu, Shuqing|Guo, Chunmei|Wang, Jiasheng|Greenaway, Frederick T|Sun, Ming-Zhong
PMID: 26622779
Journal: J Biol Chem. 2016 Feb 26;291(9):4462-72.
Title: The Transcription Factor p8 Regulates Autophagy in Response to Palmitic Acid Stress via a Mammalian Target of Rapamycin (mTOR)-independent Signaling Pathway.
Author: Jia, Sheng-Nan|Lin, Cheng|Chen, Dian-Fu|Li, An-Qi|Dai, Li|Zhang, Li|Zhao, Ling-Ling|Yang, Jin-Shu|Yang, Fan|Yang, Wei-Jun
PMID: 26733200
Journal: Biochem Biophys Res Commun. 2016 Feb 26;471(1):205-12.
Title: Cobalt chloride-mediated protein kinase Calpha (PKCalpha) phosphorylation induces hypoxia-inducible factor 1alpha (HIF1alpha) in the nucleus of gastric cancer cell.
Author: Rath, Suvasmita|Anand, Aditya|Ghosh, Nilabh|Das, Lopamudra|Kokate, Shrikant B|Dixit, Pragyesh|Majhi, Swetapadma|Rout, Niranjan|Singh, Shivaram P|Bhattacharyya, Asima
PMID: 26826385
Journal: Medicine (Baltimore). 2017 Jan;96(4):e5691.
Title: Identifying key stage-specific genes and transcription factors for gastric cancer based on RNA-sequencing data.
Author: Wang, Yan
PMID: 28121923
Journal: Oncotarget. 2017 May 30;8(22):36171-36184.
Title: Tumor and serum gamma-glutamyl transpeptidase, new prognostic and molecular interpretation of an old biomarker in gastric cancer.
Author: Wang, Qinchuan|Shu, Xiang|Dong, Yong|Zhou, Jichun|Teng, Rongyue|Shen, Jianguo|Chen, Yongxia|Dong, Mingjun|Zhang, Wenjun|Huang, Yasheng|Xie, Shuduo|Wei, Qun|Zhao, Wenhe|Chen, Wenjun|Yuan, Xiaoming|Qi, Xu|Wang, Linbo
PMID: 28404903
Journal: J Nat Med. 2018 Jan;72(1):252-259.
Title: 18beta-glycyrrhetinic acid inhibits migration and invasion of human gastric cancer cells via the ROS/PKC-alpha/ERK pathway.
Author: Cai, Hongke|Chen, Xi|Zhang, Jianbo|Wang, Jijian
PMID: 29098529