Primary Site >> Stomach Cancer
Gene >> PRKCA
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Ref: Protein kinase C alpha is the isoform responsible for inhibition of histamine H2 receptor mediated stimulation of adenylate cyclase in the human gastric cancer cell line HGT-1. PMID: 8359445 |
Ref: The alpha isoform of protein kinase C inhibits histamine-stimulated adenylate cyclase activity in a particulate fraction of the human gastric cancer cell line HGT-1. PMID: 7544678 |
Ref: [Co-regulative effect of PKA-RII and PKC-alpha kinase subspecies on expression of c-myc and c-H-ras in human gastric cancer cells (MGC 80-3)]. PMID: 9639807 |
Ref: Protein kinase Calpha promotes apoptotic cell death in gastric cancer cells depending upon loss of anchorage. PMID: 10523838 |
Ref: Selective inhibition of cyclooxygenase-2 enhances mitomycin-C-induced apoptosis. PMID: 10803922 |
Ref: Resveratrol-induced inactivation of human gastric adenocarcinoma cells through a protein kinase C-mediated mechanism. PMID: 11709203 Ref: [Expression and function of protein kinase C-alpha and beta I isoenzymes in drug-resistant gastric cancer cells]. PMID: 11783010 Ref: [Alteration of subcellular distribution of protein kinase C isoforms in swelling-activated multi-drug-resistant gastric cancer cells and its significance]. PMID: 11798893 |
Ref: PKCalpha translocation from mitochondria to nucleus is closely related to induction of apoptosis in gastric cancer cells. PMID: 18759046 |
Ref: Roles of PLC-gamma2 and PKCalpha in TPA-induced apoptosis of gastric cancer cells. PMID: 14606067 |
Ref: [Effect of PKC inhibitor on P-gp expression and drug-resistance in MGC803 cells]. PMID: 15087026 Ref: Antisense targeting protein kinase C alpha and beta1 inhibits gastric carcinogenesis. PMID: 15313921 Ref: Induction of cyclooxygenase-2 overexpression in human gastric epithelial cells by Helicobacter pylori involves TLR2/TLR9 and c-Src-dependent nuclear factor-kappaB activation. PMID: 15456896 |
Ref: Overexpression of protein kinase Calpha mRNA may be an independent prognostic marker for gastric carcinoma. PMID: 18314869 |
Ref: Antisense expression of PKCalpha improved sensitivity of SGC7901/VCR cells to doxorubicin. PMID: 19291828 |
Ref: 12-O-tetradecanoylphorbol-1, 3-acetate induces the negative regulation of protein kinase B by protein kinase Calpha during gastric cancer cell apoptosis. PMID: 20428959 |
Ref: Transcriptional regulation of claudin-18 via specific protein kinase C signaling pathways and modification of DNA methylation in human pancreatic cancer cells. PMID: 21381080 |
Ref: Clinicopathological correlation and prognostic significance of protein kinase calpha overexpression in human gastric carcinoma. PMID: 23468872 Ref: [Expressions of COX-2, PKC-alpha and miR-101 in gastric cancer and their correlations]. PMID: 23644120 Ref: Mycophenolic acid inhibits migration and invasion of gastric cancer cells via multiple molecular pathways. PMID: 24260584 |
Ref: Effect of resveratrol on proliferation and apoptosis of human pancreatic cancer MIA PaCa-2 cells may involve inhibition of the Hedgehog signaling pathway. PMID: 25190613 Ref: The inhibitory effect of pseudolaric acid B on gastric cancer and multidrug resistance via Cox-2/PKC-alpha/P-gp pathway. PMID: 25250794 |
Ref: Role of annexin A6 in cancer. PMID: 26622779 |
Ref: The Transcription Factor p8 Regulates Autophagy in Response to Palmitic Acid Stress via a Mammalian Target of Rapamycin (mTOR)-independent Signaling Pathway. PMID: 26733200 Ref: Cobalt chloride-mediated protein kinase Calpha (PKCalpha) phosphorylation induces hypoxia-inducible factor 1alpha (HIF1alpha) in the nucleus of gastric cancer cell. PMID: 26826385 |
Ref: Identifying key stage-specific genes and transcription factors for gastric cancer based on RNA-sequencing data. PMID: 28121923 Ref: Tumor and serum gamma-glutamyl transpeptidase, new prognostic and molecular interpretation of an old biomarker in gastric cancer. PMID: 28404903 |
Ref: 18beta-glycyrrhetinic acid inhibits migration and invasion of human gastric cancer cells via the ROS/PKC-alpha/ERK pathway. PMID: 29098529 |