Primary Site >> Colorectal Cancer
Gene >> PRKAA2
| 1. | |||||||||||
| Journal: | J Exp Clin Cancer Res. 2004 Jun;23(2):263-8. | ||||||||||
| Title: | Strong association of ARK5 with tumor invasion and metastasis. | ||||||||||
| Author: | Kusakai, G|Suzuki, A|Ogura, T|Kaminishi, M|Esumi, H | ||||||||||
| PMID: | 15354411 | ||||||||||
| 2. | |||||||||||
| Journal: | Cancer Res. 2006 Oct 15;66(20):10057-63. | ||||||||||
| Title: | Selenium regulates cyclooxygenase-2 and extracellular signal-regulated kinase signaling pathways by activating AMP-activated protein kinase in colon cancer cells. | ||||||||||
| Author: | Hwang, Jin-Taek|Kim, Young Min|Surh, Young-Joon|Baik, Haing Woon|Lee, Seong-Kyu|Ha, Joohun|Park, Ock Jin | ||||||||||
| PMID: | 17047069 | ||||||||||
| 3. | |||||||||||
| Journal: | Ann N Y Acad Sci. 2006 Dec;1091:102-9. | ||||||||||
| Title: | Differential modulation of AMPK signaling pathways by low or high levels of exogenous reactive oxygen species in colon cancer cells. | ||||||||||
| Author: | Park, In-Ja|Hwang, Jin-Taek|Kim, Young Min|Ha, Joohun|Park, Ock Jin | ||||||||||
| PMID: | 17341607 | ||||||||||
| 4. | |||||||||||
| Journal: | Cancer Lett. 2007 Mar 8;247(1):115-21. | ||||||||||
| Title: | Apoptotic effect of EGCG in HT-29 colon cancer cells via AMPK signal pathway. | ||||||||||
| Author: | Hwang, Jin-Taek|Ha, Joohun|Park, In-Ja|Lee, Seong-Kyu|Baik, Haing Woon|Kim, Young Min|Park, Ock Jin | ||||||||||
| PMID: | 16797120 | ||||||||||
| 5. | |||||||||||
| Journal: | Ann N Y Acad Sci. 2007 Jan;1095:441-8. | ||||||||||
| Title: | Resveratrol induces apoptosis in chemoresistant cancer cells via modulation of AMPK signaling pathway. | ||||||||||
| Author: | Hwang, Jin-Taek|Kwak, Dong Wook|Lin, Sun Kyo|Kim, Hye Min|Kim, Young Min|Park, Ock Jin | ||||||||||
| PMID: | 17404056 | ||||||||||
| 6. | |||||||||||
| Journal: | Ann N Y Acad Sci. 2007 Jan;1095:496-503. | ||||||||||
| Title: | Involvement of AMPK signaling cascade in capsaicin-induced apoptosis of HT-29 colon cancer cells. | ||||||||||
| Author: | Kim, Young Min|Hwang, Jin-Taek|Kwak, Dong Wook|Lee, Yun Kyung|Park, Ock Jin | ||||||||||
| PMID: | 17404062 | ||||||||||
| 7. | |||||||||||
| Journal: | Cancer Prev Res (Phila). 2008 Oct;1(5):369-75. | ||||||||||
| Title: | The effects of adiponectin and metformin on prostate and colon neoplasia involve activation of AMP-activated protein kinase. | ||||||||||
| Author: | Zakikhani, Mahvash|Dowling, Ryan J O|Sonenberg, Nahum|Pollak, Michael N | ||||||||||
| PMID: | 19138981 | ||||||||||
| 8. | |||||||||||
| Journal: | Exp Mol Med. 2009 Mar 31;41(3):201-7. | ||||||||||
| Title: | AMP kinase/cyclooxygenase-2 pathway regulates proliferation and apoptosis of cancer cells treated with quercetin. | ||||||||||
| Author: | Lee, Yun Kyoung|Park, Song Yi|Kim, Young Min|Lee, Won Sup|Park, Ock Jin | ||||||||||
| PMID: | 19293639 | ||||||||||
| 9. | |||||||||||
| Journal: | Ann N Y Acad Sci. 2009 Aug;1171:489-94. | ||||||||||
| Title: | Regulatory effect of the AMPK-COX-2 signaling pathway in curcumin-induced apoptosis in HT-29 colon cancer cells. | ||||||||||
| Author: | Lee, Yun-Kyoung|Park, Song Yi|Kim, Young-Min|Park, Ock Jin | ||||||||||
| PMID: | 19723094 | ||||||||||
| 10. | |||||||||||
| Journal: | Ann N Y Acad Sci. 2009 Aug;1171:564-9. | ||||||||||
| Title: | Effects of cotreatment of 12-O-tetradecanoylphorbol-13-acetate and H2O2 on apoptotic regulation via AMP-activated protein kinase-cyclooxygenase-2 signals. | ||||||||||
| Author: | Lee, Yun-Kyoung|Lee, Mee-Sook|Kim, Young-Min|Park, Ock Jin | ||||||||||
| PMID: | 19723105 | ||||||||||
| 11. | |||||||||||
| Journal: | J Agric Food Chem. 2009 Nov 25;57(22):10573-8. | ||||||||||
| Title: | Compound K induces apoptosis via CAMK-IV/AMPK pathways in HT-29 colon cancer cells. | ||||||||||
| Author: | Kim, Do Yeon|Park, Min Woo|Yuan, Hai Dan|Lee, Hyo Jung|Kim, Sung Hoon|Chung, Sung Hyun | ||||||||||
| PMID: | 19845353 | ||||||||||
| 12. | |||||||||||
| Journal: | J Biol Chem. 2010 May 7;285(19):14617-27. | ||||||||||
| Title: | AMP-activated protein kinase antagonizes pro-apoptotic extracellular signal-regulated kinase activation by inducing dual-specificity protein phosphatases in response to glucose deprivation in HCT116 carcinoma. | ||||||||||
| Author: | Kim, Min-Jung|Park, In-Ja|Yun, Hee|Kang, Insug|Choe, Wonchae|Kim, Sung-Soo|Ha, Joohun | ||||||||||
| PMID: | 20220132 | ||||||||||
| 13. | |||||||||||
| Journal: | Am J Physiol Gastrointest Liver Physiol. 2010 Jul;299(1):G136-43. | ||||||||||
| Title: | The apical (hPepT1) and basolateral peptide transport systems of Caco-2 cells are regulated by AMP-activated protein kinase. | ||||||||||
| Author: | Pieri, Myrtani|Christian, Helen C|Wilkins, Robert J|Boyd, C A R|Meredith, David | ||||||||||
| PMID: | 20430871 | ||||||||||
| 14. | |||||||||||
| Journal: | Carcinogenesis. 2011 Apr;32(4):545-53. | ||||||||||
| Title: | p-HPEA-EDA, a phenolic compound of virgin olive oil, activates AMP-activated protein kinase to inhibit carcinogenesis. | ||||||||||
| Author: | Khanal, Prem|Oh, Won-Keun|Yun, Hyo Jeong|Namgoong, Gwang Mo|Ahn, Sang-Gun|Kwon, Seong-Min|Choi, Hoo-Kyun|Choi, Hong Seok | ||||||||||
| PMID: | 21216846 | ||||||||||
| 15. | |||||||||||
| Journal: | Anticancer Res. 2011 Feb;31(2):421-6. | ||||||||||
| Title: | Addition of 2-deoxyglucose enhances growth inhibition but reverses acidification in colon cancer cells treated with phenformin. | ||||||||||
| Author: | Lea, Michael A|Chacko, Jerel|Bolikal, Sandhya|Hong, Ji Y|Chung, Ryan|Ortega, Andres|desbordes, Charles | ||||||||||
| PMID: | 21378320 | ||||||||||
| 16. | |||||||||||
| Journal: | Oncol Rep. 2012 May;27(5):1407-12. | ||||||||||
| Title: | Widdrol induces apoptosis via activation of AMP-activated protein kinase in colon cancer cells. | ||||||||||
| Author: | Kang, Moo Rim|Park, Song-Kyu|Lee, Chang Woo|Cho, Ig Jun|Jo, Yeong Nang|Yang, Jeong Wook|Kim, Jin-Ah|Yun, Jieun|Lee, Ki Hoon|Kwon, Hyun Ju|Kim, Byung Woo|Lee, Kiho|Kang, Jong Soon|Kim, Hwan Mook | ||||||||||
| PMID: | 22266984 | ||||||||||
| 17. | |||||||||||
| Journal: | Gastroenterology. 2012 Jun;142(7):1504-15.e3. | ||||||||||
| Title: | Aspirin inhibits mTOR signaling, activates AMP-activated protein kinase, and induces autophagy in colorectal cancer cells. | ||||||||||
| Author: | Din, Farhat V N|Valanciute, Asta|Houde, Vanessa P|Zibrova, Daria|Green, Kevin A|Sakamoto, Kei|Alessi, Dario R|Dunlop, Malcolm G | ||||||||||
| PMID: | 22406476 | ||||||||||
| 18. | |||||||||||
| Journal: | Biochem J. 2012 Jun 1;444(2):249-59. | ||||||||||
| Title: | AMPK and GCN2-ATF4 signal the repression of mitochondria in colon cancer cells. | ||||||||||
| Author: | Martinez-Reyes, Inmaculada|Sanchez-Arago, Maria|Cuezva, Jose M | ||||||||||
| PMID: | 22435535 | ||||||||||
| 19. | |||||||||||
| Journal: | Biol Pharm Bull. 2012;35(9):1614-20. | ||||||||||
| Title: | Magnolol-induced apoptosis in HCT-116 colon cancer cells is associated with the AMP-activated protein kinase signaling pathway. | ||||||||||
| Author: | Park, Jun Beom|Lee, Myung Sun|Cha, Eun Young|Lee, Jin Sun|Sul, Ji Young|Song, In Sang|Kim, Ji Yeon | ||||||||||
| PMID: | 22975518 | ||||||||||
| 20. | |||||||||||
| Journal: | Oncol Lett. 2013 Nov;6(5):1346-1350. | ||||||||||
| Title: | Pro-apoptotic and migration-suppressing potential of EGCG, and the involvement of AMPK in the p53-mediated modulation of VEGF and MMP-9 expression. | ||||||||||
| Author: | Park, Song Yi|Jung, Chang Hee|Song, Bokyung|Park, Ock Jin|Kim, Young-Min | ||||||||||
| PMID: | 24179522 | ||||||||||
| 21. | |||||||||||
| Journal: | Cell Signal. 2013 Oct;25(10):1993-2002. | ||||||||||
| Title: | Activation of AMP-activated protein kinase (AMPK) mediates plumbagin-induced apoptosis and growth inhibition in cultured human colon cancer cells. | ||||||||||
| Author: | Chen, Min-Bin|Zhang, Yan|Wei, Mu-Xin|Shen, Wei|Wu, Xiao-Yang|Yao, Chen|Lu, Pei-Hua | ||||||||||
| PMID: | 23712032 | ||||||||||
| 22. | |||||||||||
| Journal: | J Nucl Med. 2013 Feb;54(2):252-8. | ||||||||||
| Title: | Metformin--an adjunct antineoplastic therapy--divergently modulates tumor metabolism and proliferation, interfering with early response prediction by 18F-FDG PET imaging. | ||||||||||
| Author: | Habibollahi, Peiman|van den Berg, Nynke S|Kuruppu, Darshini|Loda, Massimo|Mahmood, Umar | ||||||||||
| PMID: | 23376854 | ||||||||||
| 23. | |||||||||||
| Journal: | Am J Pathol. 2013 May;182(5):1800-10. | ||||||||||
| Title: | Inhibition of ATP citrate lyase induces an anticancer effect via reactive oxygen species: AMPK as a predictive biomarker for therapeutic impact. | ||||||||||
| Author: | Migita, Toshiro|Okabe, Sachiko|Ikeda, Kazutaka|Igarashi, Saori|Sugawara, Shoko|Tomida, Akihiro|Taguchi, Ryo|Soga, Tomoyoshi|Seimiya, Hiroyuki | ||||||||||
| PMID: | 23506848 | ||||||||||
| 24. | |||||||||||
| Journal: | Metabolism. 2014 May;63(5):672-81. | ||||||||||
| Title: | Globular adiponectin and its downstream target genes are up-regulated locally in human colorectal tumors: ex vivo and in vitro studies. | ||||||||||
| Author: | Vetvik, Katja Kannisto|Sonerud, Tonje|Lindeberg, Mona|Luders, Torben|Storkson, Ragnhild H|Jonsdottir, Kristin|Frengen, Eirik|Pietilainen, Kirsi H|Bukholm, Ida | ||||||||||
| PMID: | 24636346 | ||||||||||
| 25. | |||||||||||
| Journal: | Biochem Pharmacol. 2014 Aug 1;90(3):265-75. | ||||||||||
| Title: | Autophagy inhibition switches low-dose camptothecin-induced premature senescence to apoptosis in human colorectal cancer cells. | ||||||||||
| Author: | Zhang, Jian-wei|Zhang, Shan-shan|Song, Jian-rui|Sun, Kai|Zong, Chen|Zhao, Qiu-dong|Liu, Wen-ting|Li, Rong|Wu, Meng-chao|Wei, Li-xin | ||||||||||
| PMID: | 24858802 | ||||||||||
| 26. | |||||||||||
| Journal: | PLoS One. 2014 Jun 24;9(6):e99631. | ||||||||||
| Title: | Caffeic acid derivatives inhibit the growth of colon cancer: involvement of the PI3-K/Akt and AMPK signaling pathways. | ||||||||||
| Author: | Chiang, En-Pei Isabel|Tsai, Shu-Yao|Kuo, Yueh-Hsiung|Pai, Man-Hui|Chiu, Hsi-Lin|Rodriguez, Raymond L|Tang, Feng-Yao | ||||||||||
| PMID: | 24960186 | ||||||||||
| 27. | |||||||||||
| Journal: | Oncol Rep. 2015 Jan;33(1):223-9. | ||||||||||
| Title: | Kazinol C from Broussonetia kazinoki activates AMP-activated protein kinase to induce antitumorigenic effects in HT-29 colon cancer cells. | ||||||||||
| Author: | Kim, Hak-Su|Lim, Jihyun|Lee, Da Yeon|Ryu, Jae-Ha|Lim, Jong-Seok | ||||||||||
| PMID: | 25394483 | ||||||||||
| 28. | |||||||||||
| Journal: | Hum Pathol. 2015 May;46(5):753-60. | ||||||||||
| Title: | Frameshift mutations in mammalian target of rapamycin pathway genes and their regional heterogeneity in sporadic colorectal cancers. | ||||||||||
| Author: | Choi, Mi Ryoung|Yoo, Nam Jin|An, Chang Hyeok|Lee, Sug Hyung | ||||||||||
| PMID: | 25776026 | ||||||||||
| 29. | |||||||||||
| Journal: | Oncotarget. 2016 May 24;7(21):31336-49. | ||||||||||
| Title: | Nesfatin-1/Nucleobindin-2 enhances cell migration, invasion, and epithelial-mesenchymal transition via LKB1/AMPK/TORC1/ZEB1 pathways in colon cancer. | ||||||||||
| Author: | Kan, Jung-Yu|Yen, Meng-Chi|Wang, Jaw-Yuan|Wu, Deng-Chyang|Chiu, Yen-Jung|Ho, Ya-Wen|Kuo, Po-Lin | ||||||||||
| PMID: | 27150059 | ||||||||||
| 30. | |||||||||||
| Journal: | Free Radic Biol Med. 2016 Dec;101:511-523. | ||||||||||
| Title: | Sestrin2 inhibits hypoxia-inducible factor-1alpha accumulation via AMPK-mediated prolyl hydroxylase regulation. | ||||||||||
| Author: | Seo, Kyuhwa|Seo, Suho|Ki, Sung Hwan|Shin, Sang Mi | ||||||||||
| PMID: | 27840318 | ||||||||||
| 31. | |||||||||||
| Journal: | Oncol Lett. 2016 May;11(5):3197-3201. | ||||||||||
| Title: | Re-sensitization of radiation resistant colorectal cancer cells to radiation through inhibition of AMPK pathway. | ||||||||||
| Author: | Jin, Hongyong|Gao, Sujie|Guo, Huiling|Ren, Shengnan|Ji, Fujian|Liu, Zhuo|Chen, Xuebo | ||||||||||
| PMID: | 27123089 | ||||||||||
| 32. | |||||||||||
| Journal: | Mol Med Rep. 2016 Jun;13(6):4681-8. | ||||||||||
| Title: | Apoptotic effects of extract from Cnidium monnieri (L.) Cusson by adenosine monosphosphate-activated protein kinase-independent pathway in HCT116 colon cancer cells. | ||||||||||
| Author: | Lim, Eun Gyeong|Kim, Guen Tae|Lee, Se Hee|Kim, Sang-Yong|Kim, Young Min | ||||||||||
| PMID: | 27082059 | ||||||||||
| 33. | |||||||||||
| Journal: | Oncotarget. 2016 Mar 29;7(13):16349-61. | ||||||||||
| Title: | AMPK-mediated up-regulation of mTORC2 and MCL-1 compromises the anti-cancer effects of aspirin. | ||||||||||
| Author: | Gao, Mei|Kong, Qingbin|Hua, Hui|Yin, Yancun|Wang, Jiao|Luo, Ting|Jiang, Yangfu | ||||||||||
| PMID: | 26918349 | ||||||||||
| 34. | |||||||||||
| Journal: | Int J Oncol. 2017 Jan;50(1):161-172. | ||||||||||
| Title: | Metabolic reprogramming and AMPKalpha1 pathway activation by caulerpin in colorectal cancer cells. | ||||||||||
| Author: | Yu, Hua|Zhang, Huiqin|Dong, Mingjun|Wu, Zhou|Shen, Zhonglei|Xie, Yangyang|Kong, Zhenfang|Dai, Xiaoyu|Xu, Binbin | ||||||||||
| PMID: | 27922662 | ||||||||||
| 35. | |||||||||||
| Journal: | Toxicol Appl Pharmacol. 2017 Jul 1;326:25-33. | ||||||||||
| Title: | Licoricidin inhibits the growth of SW480 human colorectal adenocarcinoma cells in vitro and in vivo by inducing cycle arrest, apoptosis and autophagy. | ||||||||||
| Author: | Ji, Shuai|Tang, Shunan|Li, Kai|Li, Ziwei|Liang, Wenfei|Qiao, Xue|Wang, Qi|Yu, Siwang|Ye, Min | ||||||||||
| PMID: | 28416456 | ||||||||||
| 36. | |||||||||||
| Journal: | Oncol Lett. 2017 Nov;14(5):5831-5838. | ||||||||||
| Title: | Ginkgolic acid inhibits the invasiveness of colon cancer cells through AMPK activation. | ||||||||||
| Author: | Qiao, Lina|Zheng, Jianbao|Jin, Xianzhen|Wei, Guangbing|Wang, Guanghui|Sun, Xuejun|Li, Xuqi | ||||||||||
| PMID: | 29113214 | ||||||||||
| 37. | |||||||||||
| Journal: | Exp Ther Med. 2018 Jan;15(1):864-872. | ||||||||||
| Title: | SDHB downregulation facilitates the proliferation and invasion of colorectal cancer through AMPK functions excluding those involved in the modulation of aerobic glycolysis. | ||||||||||
| Author: | Xiao, Zhiming|Liu, Shaojun|Ai, Feiyan|Chen, Xiong|Li, Xiayu|Liu, Rui|Ren, Weiguo|Zhang, Xuemei|Shu, Peng|Zhang, Decai | ||||||||||
| PMID: | 29399091 | ||||||||||
| 38. | |||||||||||
| Journal: | Front Pharmacol. 2018 Feb 5;9:68. | ||||||||||
| Title: | Rosmarinic Acid Activates AMPK to Inhibit Metastasis of Colorectal Cancer. | ||||||||||
| Author: | Han, Yo-Han|Kee, Ji-Ye|Hong, Seung-Heon | ||||||||||
| PMID: | 29459827 | ||||||||||
| 39. | |||||||||||
| Journal: | Sci Rep. 2018 Feb 28;8(1):3770. | ||||||||||
| Title: | A Functional Signature Ontology (FUSION) screen detects an AMPK inhibitor with selective toxicity toward human colon tumor cells. | ||||||||||
| Author: | Das, Binita|Neilsen, Beth K|Fisher, Kurt W|Gehring, Drew|Hu, Youcai|Volle, Deanna J|Kim, Hyun Seok|McCall, Jamie L|Kelly, David L|MacMillan, John B|White, Michael A|Lewis, Robert E | ||||||||||
| PMID: | 29491475 | ||||||||||
| 40. | |||||||||||
| Journal: | Mol Med Rep. 2018 Aug;18(2):1692-1703. | ||||||||||
| Title: | Tanshinone IIA regulates colorectal cancer apoptosis via attenuation of Parkinmediated mitophagy by suppressing AMPK/Skp2 pathways. | ||||||||||
| Author: | He, Lili|Gu, Kebo | ||||||||||
| PMID: | 29845197 | ||||||||||
| 41. | |||||||||||
| Journal: | Oncol Lett. 2018 Jul;16(1):1291-1297. | ||||||||||
| Title: | Liver kinase B1/adenosine monophosphate-activated protein kinase signaling axis induces p21/WAF1 expression in a p53-dependent manner. | ||||||||||
| Author: | Ma, Qing|Xiao, Ping|Sun, Linlin|Wang, Jing|Zhong, Diansheng | ||||||||||
| PMID: | 29963200 | ||||||||||
| 42. | |||||||||||
| Journal: | BMB Rep. 2018 Oct;51(10):532-537. | ||||||||||
| Title: | Cordycepin inhibits lipopolysaccharide-induced cell migration and invasion in human colorectal carcinoma HCT-116 cells through down-regulation of prostaglandin E2 receptor EP4. | ||||||||||
| Author: | Jeong, Jin-Woo|Park, Cheol|Cha, Hee-Jae|Hong, Su Hyun|Park, Shin-Hyung|Kim, Gi-Young|Kim, Woo Jean|Kim, Cheol Hong|Song, Kyoung Seob|Choi, Yung Hyun | ||||||||||
| PMID: | 30269738 | ||||||||||