Primary Site >> Colorectal Cancer
Gene >> PRKAA2
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Ref: Strong association of ARK5 with tumor invasion and metastasis. PMID: 15354411 |
Ref: Selenium regulates cyclooxygenase-2 and extracellular signal-regulated kinase signaling pathways by activating AMP-activated protein kinase in colon cancer cells. PMID: 17047069 Ref: Differential modulation of AMPK signaling pathways by low or high levels of exogenous reactive oxygen species in colon cancer cells. PMID: 17341607 |
Ref: Apoptotic effect of EGCG in HT-29 colon cancer cells via AMPK signal pathway. PMID: 16797120 Ref: Resveratrol induces apoptosis in chemoresistant cancer cells via modulation of AMPK signaling pathway. PMID: 17404056 Ref: Involvement of AMPK signaling cascade in capsaicin-induced apoptosis of HT-29 colon cancer cells. PMID: 17404062 |
Ref: The effects of adiponectin and metformin on prostate and colon neoplasia involve activation of AMP-activated protein kinase. PMID: 19138981 |
Ref: AMP kinase/cyclooxygenase-2 pathway regulates proliferation and apoptosis of cancer cells treated with quercetin. PMID: 19293639 Ref: Regulatory effect of the AMPK-COX-2 signaling pathway in curcumin-induced apoptosis in HT-29 colon cancer cells. PMID: 19723094 Ref: Effects of cotreatment of 12-O-tetradecanoylphorbol-13-acetate and H2O2 on apoptotic regulation via AMP-activated protein kinase-cyclooxygenase-2 signals. PMID: 19723105 Ref: Compound K induces apoptosis via CAMK-IV/AMPK pathways in HT-29 colon cancer cells. PMID: 19845353 |
Ref: AMP-activated protein kinase antagonizes pro-apoptotic extracellular signal-regulated kinase activation by inducing dual-specificity protein phosphatases in response to glucose deprivation in HCT116 carcinoma. PMID: 20220132 Ref: The apical (hPepT1) and basolateral peptide transport systems of Caco-2 cells are regulated by AMP-activated protein kinase. PMID: 20430871 |
Ref: p-HPEA-EDA, a phenolic compound of virgin olive oil, activates AMP-activated protein kinase to inhibit carcinogenesis. PMID: 21216846 Ref: Addition of 2-deoxyglucose enhances growth inhibition but reverses acidification in colon cancer cells treated with phenformin. PMID: 21378320 |
Ref: Widdrol induces apoptosis via activation of AMP-activated protein kinase in colon cancer cells. PMID: 22266984 Ref: Aspirin inhibits mTOR signaling, activates AMP-activated protein kinase, and induces autophagy in colorectal cancer cells. PMID: 22406476 Ref: AMPK and GCN2-ATF4 signal the repression of mitochondria in colon cancer cells. PMID: 22435535 Ref: Magnolol-induced apoptosis in HCT-116 colon cancer cells is associated with the AMP-activated protein kinase signaling pathway. PMID: 22975518 |
Ref: Metformin--an adjunct antineoplastic therapy--divergently modulates tumor metabolism and proliferation, interfering with early response prediction by 18F-FDG PET imaging. PMID: 23376854 Ref: Inhibition of ATP citrate lyase induces an anticancer effect via reactive oxygen species: AMPK as a predictive biomarker for therapeutic impact. PMID: 23506848 Ref: Activation of AMP-activated protein kinase (AMPK) mediates plumbagin-induced apoptosis and growth inhibition in cultured human colon cancer cells. PMID: 23712032 Ref: Pro-apoptotic and migration-suppressing potential of EGCG, and the involvement of AMPK in the p53-mediated modulation of VEGF and MMP-9 expression. PMID: 24179522 |
Ref: Globular adiponectin and its downstream target genes are up-regulated locally in human colorectal tumors: ex vivo and in vitro studies. PMID: 24636346 Ref: Autophagy inhibition switches low-dose camptothecin-induced premature senescence to apoptosis in human colorectal cancer cells. PMID: 24858802 Ref: Caffeic acid derivatives inhibit the growth of colon cancer: involvement of the PI3-K/Akt and AMPK signaling pathways. PMID: 24960186 |
Ref: Kazinol C from Broussonetia kazinoki activates AMP-activated protein kinase to induce antitumorigenic effects in HT-29 colon cancer cells. PMID: 25394483 Ref: Frameshift mutations in mammalian target of rapamycin pathway genes and their regional heterogeneity in sporadic colorectal cancers. PMID: 25776026 |
Ref: AMPK-mediated up-regulation of mTORC2 and MCL-1 compromises the anti-cancer effects of aspirin. PMID: 26918349 Ref: Apoptotic effects of extract from Cnidium monnieri (L.) Cusson by adenosine monosphosphate-activated protein kinase-independent pathway in HCT116 colon cancer cells. PMID: 27082059 Ref: Re-sensitization of radiation resistant colorectal cancer cells to radiation through inhibition of AMPK pathway. PMID: 27123089 Ref: Nesfatin-1/Nucleobindin-2 enhances cell migration, invasion, and epithelial-mesenchymal transition via LKB1/AMPK/TORC1/ZEB1 pathways in colon cancer. PMID: 27150059 Ref: Sestrin2 inhibits hypoxia-inducible factor-1alpha accumulation via AMPK-mediated prolyl hydroxylase regulation. PMID: 27840318 |
Ref: Metabolic reprogramming and AMPKalpha1 pathway activation by caulerpin in colorectal cancer cells. PMID: 27922662 Ref: Licoricidin inhibits the growth of SW480 human colorectal adenocarcinoma cells in vitro and in vivo by inducing cycle arrest, apoptosis and autophagy. PMID: 28416456 Ref: Ginkgolic acid inhibits the invasiveness of colon cancer cells through AMPK activation. PMID: 29113214 |
Ref: SDHB downregulation facilitates the proliferation and invasion of colorectal cancer through AMPK functions excluding those involved in the modulation of aerobic glycolysis. PMID: 29399091 Ref: Rosmarinic Acid Activates AMPK to Inhibit Metastasis of Colorectal Cancer. PMID: 29459827 Ref: A Functional Signature Ontology (FUSION) screen detects an AMPK inhibitor with selective toxicity toward human colon tumor cells. PMID: 29491475 Ref: Tanshinone IIA regulates colorectal cancer apoptosis via attenuation of Parkinmediated mitophagy by suppressing AMPK/Skp2 pathways. PMID: 29845197 Ref: Liver kinase B1/adenosine monophosphate-activated protein kinase signaling axis induces p21/WAF1 expression in a p53-dependent manner. PMID: 29963200 Ref: Cordycepin inhibits lipopolysaccharide-induced cell migration and invasion in human colorectal carcinoma HCT-116 cells through down-regulation of prostaglandin E2 receptor EP4. PMID: 30269738 |