Primary Site >> Liver Cancer

Gene >> PRDM2

Journal: Int J Cancer. 1999 Nov 12;83(4):541-6.
Title: Decreased RIZ1 expression but not RIZ2 in hepatoma and suppression of hepatoma tumorigenicity by RIZ1.
Author: Jiang, G l|Liu, L|Buyse, I M|Simon, D|Huang, S
PMID: 10508492
Journal: Genes Chromosomes Cancer. 2000 Jul;28(3):269-75.
Title: Mapping of a minimal deleted region in human hepatocellular carcinoma to 1p36.13-p36.23 and mutational analysis of the RIZ (PRDM2) gene localized to the region.
Author: Fang, W|Piao, Z|Simon, D|Sheu, J C|Huang, S
PMID: 10862032
Journal: Br J Cancer. 2001 Mar 23;84(6):743-7.
Title: Preferential loss of a polymorphic RIZ allele in human hepatocellular carcinoma.
Author: Fang, W|Piao, Z|Buyse, I M|Simon, D|Sheu, J C|Perucho, M|Huang, S
PMID: 11259086
Journal: Cancer Res. 2001 Nov 15;61(22):8094-9.
Title: Hypermethylation in human cancers of the RIZ1 tumor suppressor gene, a member of a histone/protein methyltransferase superfamily.
Author: Du, Y|Carling, T|Fang, W|Piao, Z|Sheu, J C|Huang, S
PMID: 11719434
Journal: Mol Carcinog. 2003 Feb;36(2):90-9.
Title: Identification of three 11p11.2 candidate liver tumor suppressors through analysis of known human genes.
Author: Ricketts, Sharon L|Carter, Jennifer C|Coleman, William B
PMID: 12557265
Journal: Oncogene. 2004 Jun 17;23(28):4903-10.
Title: PRDM5 is silenced in human cancers and has growth suppressive activities.
Author: Deng, Qingdong|Huang, Shi
PMID: 15077163
Journal: Genes Chromosomes Cancer. 2005 Jan;42(1):34-43.
Title: Discrete breakpoint mapping and shortest region of overlap of chromosome arm 1q gain and 1p loss in human hepatocellular carcinoma detected by semiquantitative microsatellite analysis.
Author: Nishimura, Takafumi|Nishida, Naoshi|Itoh, Teruaki|Komeda, Toshiki|Fukuda, Yoshihiro|Ikai, Iwao|Yamaoka, Yoshio|Nakao, Kazuwa
PMID: 15495198
Journal: Clin Cancer Res. 2005 May 15;11(10):3654-60.
Title: Distinct methylation patterns of benign and malignant liver tumors revealed by quantitative methylation profiling.
Author: Lehmann, Ulrich|Berg-Ribbe, Ina|Wingen, Luzie U|Brakensiek, Kai|Becker, Thomas|Klempnauer, Jurgen|Schlegelberger, Brigitte|Kreipe, Hans|Flemming, Peer
PMID: 15897561
Journal: J Gastroenterol Hepatol. 2006 Jan;21(1 Pt 1):15-21.
Title: Review of genetic and epigenetic alterations in hepatocarcinogenesis.
Author: Herath, Nirmitha I|Leggett, Barbara A|MacDonald, Graeme A
PMID: 16706806
Journal: J Nutr. 2007 Jan;137(1 Suppl):216S-222S.
Title: Methyl deficiency, alterations in global histone modifications, and carcinogenesis.
Author: Pogribny, Igor P|Tryndyak, Volodymyr P|Muskhelishvili, Levan|Rusyn, Ivan|Ross, Sharon A
PMID: 17182829
Journal: World J Gastroenterol. 2007 Nov 21;13(43):5718-24.
Title: Silencing SMYD3 in hepatoma demethylates RIZI promoter induces apoptosis and inhibits cell proliferation and migration.
Author: Chen, Li-Bo|Xu, Jun-Yao|Yang, Zhen|Wang, Guo-Bin
PMID: 17963297
Journal: Br J Cancer. 2007 Nov 5;97(9):1260-5.
Title: Hypermethylation of multiple genes as clonal markers in multicentric hepatocellular carcinoma.
Author: Nomoto, S|Kinoshita, T|Kato, K|Otani, S|Kasuya, H|Takeda, S|Kanazumi, N|Sugimoto, H|Nakao, A
PMID: 17968429
Journal: PLoS One. 2008;3(10):e3390.
Title: Requirement of RIZ1 for cancer prevention by methyl-balanced diet.
Author: Zhou, Wenyun|Alonso, Sergio|Takai, Daisaku|Lu, Shelly C|Yamamoto, Fumiichiro|Perucho, Manuel|Huang, Shi
PMID: 18852888
Journal: Zhonghua Zhong Liu Za Zhi. 2008 Nov;30(11):831-6.
Title: [Aberrant methylation of multiple genes and its clinical implication in hepatocellular carcinoma].
Author: Lou, Cheng|Yang, Bin|Gao, Ying-tang|Wang, Yi-jun|Nie, Fu-hua|Yuan, Qiang|Zhang, Chun-li|Du, Zhi
PMID: 19173828
Journal: Histol Histopathol. 2008 Oct;23(10):1171-5.
Title: Hyper-methylation of RIZ1 tumor suppressor gene is involved in the early tumorigenesis of hepatocellular carcinoma.
Author: Piao, G H|Piao, W H|He, Y|Zhang, H H|Wang, G Q|Piao, Z
PMID: 18712668
Journal: Hepatology. 2008 Mar;47(3):908-18.
Title: Aberrant methylation of multiple tumor suppressor genes in aging liver, chronic hepatitis, and hepatocellular carcinoma.
Author: Nishida, Naoshi|Nagasaka, Takeshi|Nishimura, Takafumi|Ikai, Iwao|Boland, C Richard|Goel, Ajay
PMID: 18161048
Journal: Cancer Sci. 2009 Jun;100(6):996-1004.
Title: Aberrant DNA methylation profile of hepatocellular carcinoma and surgically resected margin.
Author: Lou, Cheng|Du, Zhi|Yang, Bin|Gao, YingTang|Wang, YiJun|Fang, ShuChang
PMID: 19385975
Journal: Int J Oncol. 2009 Nov;35(5):1081-9.
Title: Varying etiologies lead to different molecular changes in Australian and South African hepatocellular carcinomas.
Author: Herath, Nirmitha I|Purdie, David M|Kew, Michael C|Smith, Jeffery L|Young, Joanne|Leggett, Barbara A|MacDonald, Graeme A
PMID: 19787262
Journal: J Hepatol. 2010 Nov;53(5):889-95.
Title: Epigenetic inactivation of the tumor suppressor gene RIZ1 in hepatocellular carcinoma involves both DNA methylation and histone modifications.
Author: Zhang, Cuijuan|Li, Hiuming|Wang, Yan|Liu, Wenjun|Zhang, Qinghui|Zhang, Tingguo|Zhang, Xiaoying|Han, Bo|Zhou, Gengyin
PMID: 20675009
Journal: Mutat Res. 2010 Oct 13;692(1-2):26-33.
Title: Comparative analysis of promoter methylation and gene expression endpoints between tumorous and non-tumorous tissues from HCV-positive patients with hepatocellular carcinoma.
Author: Formeister, Eric J|Tsuchiya, Masato|Fujii, Hideki|Shpyleva, Svitlana|Pogribny, Igor P|Rusyn, Ivan
PMID: 20736025
Journal: Hepatology. 2012 Sep;56(3):994-1003.
Title: Characteristic patterns of altered DNA methylation predict emergence of human hepatocellular carcinoma.
Author: Nishida, Naoshi|Kudo, Masatoshi|Nagasaka, Takeshi|Ikai, Iwao|Goel, Ajay
PMID: 22407776
Journal: Arch Toxicol. 2013 Aug;87(8):1595-607.
Title: Selective poisoning of Ctnnb1-mutated hepatoma cells in mouse liver tumors by a single application of acetaminophen.
Author: Singh, Yasmin|Braeuning, Albert|Schmid, Andreas|Pichler, Bernd J|Schwarz, Michael
PMID: 23479080
Journal: Genomics. 2013 Aug;102(2):74-83.
Title: Mutations in TP53, CTNNB1 and PIK3CA genes in hepatocellular carcinoma associated with hepatitis B and hepatitis C virus infections.
Author: Tornesello, Maria Lina|Buonaguro, Luigi|Tatangelo, Fabiana|Botti, Gerardo|Izzo, Francesco|Buonaguro, Franco M
PMID: 23583669
Journal: Nat Commun. 2013;4:2218.
Title: High frequency of telomerase reverse-transcriptase promoter somatic mutations in hepatocellular carcinoma and preneoplastic lesions.
Author: Nault, Jean Charles|Mallet, Maxime|Pilati, Camilla|Calderaro, Julien|Bioulac-Sage, Paulette|Laurent, Christophe|Laurent, Alexis|Cherqui, Daniel|Balabaud, Charles|Zucman-Rossi, Jessica
PMID: 23887712
Journal: Int J Cancer. 2014 Jun 15;134(12):2778-88.
Title: Genetic and epigenetic changes in fibrosis-associated hepatocarcinogenesis in mice.
Author: Chappell, Grace|Kutanzi, Kristy|Uehara, Takeki|Tryndyak, Volodymyr|Hong, Hue-Hua|Hoenerhoff, Mark|Beland, Frederick A|Rusyn, Ivan|Pogribny, Igor P
PMID: 24242335
Journal: Oncol Lett. 2015 Oct;10(4):2553-2558.
Title: Detecting abnormal methylation of tumor suppressor genes GSTP1, P16, RIZ1, and RASSF1A in hepatocellular carcinoma and its clinical significance.
Author: Qu, Zhen|Jiang, Yong|Li, Huan|Yu, DE-Cai|Ding, Yi-Tao
PMID: 26622888
Journal: Oncotarget. 2016 Dec 6;7(49):81255-81267.
Title: Meta-analysis of DNA methylation biomarkers in hepatocellular carcinoma.
Author: Zhang, Cheng|Li, Jinyun|Huang, Tao|Duan, Shiwei|Dai, Dongjun|Jiang, Danjie|Sui, Xinbing|Li, Da|Chen, Yidan|Ding, Fei|Huang, Changxin|Chen, Gongying|Wang, Kaifeng
PMID: 27835605
Journal: Oncol Rep. 2017 May;37(5):2811-2818.
Title: HBx represses RIZ1 expression by DNA methyltransferase 1 involvement in decreased miR-152 in hepatocellular carcinoma.
Author: Zhao, Zhujiang|Hu, Ying|Shen, Xiaohui|Lao, Yingbin|Zhang, Lihua|Qiu, Xuemei|Hu, Jiaojiao|Gong, Pihai|Cui, He|Lu, Sen|Zheng, Ying|Zhou, Menghan|Fan, Hong
PMID: 28339081
Journal: Hepatology. 2018 Mar 23.
Title: PRDM8 exhibits antitumor activities toward hepatocellular carcinoma by targeting NAP1L1.
Author: Chen, Zhiqiang|Gao, Wen|Pu, Liyong|Zhang, Long|Han, Guoyong|Zuo, Xueliang|Zhang, Yao|Li, Xiangcheng|Shen, Hongbing|Wu, Jindao|Wang, Xuehao
PMID: 29572888