Primary Site >> Liver Cancer
Gene >> PRDM2
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Ref: Decreased RIZ1 expression but not RIZ2 in hepatoma and suppression of hepatoma tumorigenicity by RIZ1. PMID: 10508492 |
Ref: Mapping of a minimal deleted region in human hepatocellular carcinoma to 1p36.13-p36.23 and mutational analysis of the RIZ (PRDM2) gene localized to the region. PMID: 10862032 |
Ref: Preferential loss of a polymorphic RIZ allele in human hepatocellular carcinoma. PMID: 11259086 Ref: Hypermethylation in human cancers of the RIZ1 tumor suppressor gene, a member of a histone/protein methyltransferase superfamily. PMID: 11719434 |
Ref: Identification of three 11p11.2 candidate liver tumor suppressors through analysis of known human genes. PMID: 12557265 |
Ref: PRDM5 is silenced in human cancers and has growth suppressive activities. PMID: 15077163 |
Ref: Discrete breakpoint mapping and shortest region of overlap of chromosome arm 1q gain and 1p loss in human hepatocellular carcinoma detected by semiquantitative microsatellite analysis. PMID: 15495198 Ref: Distinct methylation patterns of benign and malignant liver tumors revealed by quantitative methylation profiling. PMID: 15897561 |
Ref: Review of genetic and epigenetic alterations in hepatocarcinogenesis. PMID: 16706806 |
Ref: Methyl deficiency, alterations in global histone modifications, and carcinogenesis. PMID: 17182829 Ref: Silencing SMYD3 in hepatoma demethylates RIZI promoter induces apoptosis and inhibits cell proliferation and migration. PMID: 17963297 Ref: Hypermethylation of multiple genes as clonal markers in multicentric hepatocellular carcinoma. PMID: 17968429 |
Ref: Aberrant methylation of multiple tumor suppressor genes in aging liver, chronic hepatitis, and hepatocellular carcinoma. PMID: 18161048 Ref: Hyper-methylation of RIZ1 tumor suppressor gene is involved in the early tumorigenesis of hepatocellular carcinoma. PMID: 18712668 Ref: Requirement of RIZ1 for cancer prevention by methyl-balanced diet. PMID: 18852888 Ref: [Aberrant methylation of multiple genes and its clinical implication in hepatocellular carcinoma]. PMID: 19173828 |
Ref: Aberrant DNA methylation profile of hepatocellular carcinoma and surgically resected margin. PMID: 19385975 Ref: Varying etiologies lead to different molecular changes in Australian and South African hepatocellular carcinomas. PMID: 19787262 |
Ref: Epigenetic inactivation of the tumor suppressor gene RIZ1 in hepatocellular carcinoma involves both DNA methylation and histone modifications. PMID: 20675009 Ref: Comparative analysis of promoter methylation and gene expression endpoints between tumorous and non-tumorous tissues from HCV-positive patients with hepatocellular carcinoma. PMID: 20736025 |
Ref: Characteristic patterns of altered DNA methylation predict emergence of human hepatocellular carcinoma. PMID: 22407776 |
Ref: Selective poisoning of Ctnnb1-mutated hepatoma cells in mouse liver tumors by a single application of acetaminophen. PMID: 23479080 Ref: Mutations in TP53, CTNNB1 and PIK3CA genes in hepatocellular carcinoma associated with hepatitis B and hepatitis C virus infections. PMID: 23583669 Ref: High frequency of telomerase reverse-transcriptase promoter somatic mutations in hepatocellular carcinoma and preneoplastic lesions. PMID: 23887712 |
Ref: Genetic and epigenetic changes in fibrosis-associated hepatocarcinogenesis in mice. PMID: 24242335 |
Ref: Detecting abnormal methylation of tumor suppressor genes GSTP1, P16, RIZ1, and RASSF1A in hepatocellular carcinoma and its clinical significance. PMID: 26622888 |
Ref: Meta-analysis of DNA methylation biomarkers in hepatocellular carcinoma. PMID: 27835605 |
Ref: HBx represses RIZ1 expression by DNA methyltransferase 1 involvement in decreased miR-152 in hepatocellular carcinoma. PMID: 28339081 |
Ref: PRDM8 exhibits antitumor activities toward hepatocellular carcinoma by targeting NAP1L1. PMID: 29572888 |