Primary Site >> Colorectal Cancer

Gene >> PPM1D

Journal: J Cancer Res Clin Oncol. 2001 Dec;127(12):697-706.
Title: MRNA expression of genes altered by 5-azacytidine treatment in cancer cell lines is associated with clinicopathological parameters of human cancers.
Author: Kanai, Y|Ushijima, S|Saito, Y|Nakanishi, Y|Sakamoto, M|Hirohashi, S
PMID: 11768609
Journal: Oncogene. 2007 Mar 1;26(10):1449-58. Epub 2006 Aug 28.
Title: The Wip1 phosphatase (PPM1D) antagonizes activation of the Chk2 tumour suppressor kinase.
Author: Oliva-Trastoy, M|Berthonaud, V|Chevalier, A|Ducrot, C|Marsolier-Kergoat, M-C|Mann, C|Leteurtre, F
PMID: 16936775
Journal: Cell Stem Cell. 2007 Aug 16;1(2):180-90.
Title: Wip1 phosphatase regulates p53-dependent apoptosis of stem cells and tumorigenesis in the mouse intestine.
Author: Demidov, Oleg N|Timofeev, Oleg|Lwin, Hnin N Y|Kek, Calvina|Appella, Ettore|Bulavin, Dmitry V
PMID: 18371349
Journal: J Neurooncol. 2010 May;97(3):373-82.
Title: p53 Regulates LIF expression in human medulloblastoma cells.
Author: Baxter, Euan W|Milner, Jo
PMID: 19907922
Journal: Int J Biochem Cell Biol. 2012 Jun;44(6):896-904.
Title: p53-Independent expression of wild-type p53-induced phosphatase 1 (Wip1) in methylmethane sulfonate-treated cancer cell lines and human tumors.
Author: Park, Ji-Young|Song, Ji-Young|Kim, Hyun Mi|Han, Hye-Sook|Seol, Hyang Sook|Jang, Se Jin|Choi, Jene
PMID: 22405851
Journal: J Cell Biol. 2013 May 13;201(4):511-21.
Title: Gain-of-function mutations of PPM1D/Wip1 impair the p53-dependent G1 checkpoint.
Author: Kleiblova, Petra|Shaltiel, Indra A|Benada, Jan|Sevcik, Jan|Pechackova, Sona|Pohlreich, Petr|Voest, Emile E|Dundr, Pavel|Bartek, Jiri|Kleibl, Zdenek|Medema, Rene H|Macurek, Libor
PMID: 23649806
Journal: Asian Pac J Cancer Prev. 2013;14(3):1975-9.
Title: Expression and significance of the Wip1 proto-oncogene in colorectal cancer.
Author: Li, Zong-Tao|Zhang, Liu|Gao, Xiao-Zeng|Jiang, Xiao-Hua|Sun, Li-Qian
PMID: 23679302
Journal: Technol Cancer Res Treat. 2013 Dec;12(6):537-43.
Title: Knockdown of protein phosphatase magnesium-dependent 1 (PPM1D) through lentivirus-mediated RNA silencing inhibits colorectal carcinoma cell proliferation.
Author: Yin, Hongzhuan|Yan, Zhaopeng|Liang, Yichao|Liu, Baolin|Su, Qi
PMID: 23745790
Journal: Exp Ther Med. 2014 Aug;8(2):430-434.
Title: PPM1D is a prognostic marker and therapeutic target in colorectal cancer.
Author: Peng, Tian-Shu|He, Yong-Heng|Nie, Tian|Hu, Xiang-Dang|Lu, Hai-Yan|Yi, Jian|Shuai, Yun-Fei|Luo, Min
PMID: 25009596
Journal: Radiat Res. 2014 Sep;182(3):345-9.
Title: Wip1 abrogation decreases intestinal tumor frequency in APC(Min/+) mice irrespective of radiation quality.
Author: Suman, Shubhankar|Moon, Bo-Hyun|Thakor, Hemang|Fornace, Albert J Jr|Datta, Kamal
PMID: 25117622
Journal: Bioorg Med Chem Lett. 2014 Dec 15;24(24):5593-5596.
Title: Inhibition of C-terminal truncated PPM1D enhances the effect of doxorubicin on cell viability in human colorectal carcinoma cell line.
Author: Kozakai, Yuuki|Kamada, Rui|Kiyota, Yuhei|Yoshimura, Fumihiko|Tanino, Keiji|Sakaguchi, Kazuyasu
PMID: 25466181
Journal: Br J Cancer. 2015 Mar 17;112(6):1114-20.
Title: Truncating mutations of PPM1D are found in blood DNA samples of lung cancer patients.
Author: Zajkowicz, A|Butkiewicz, D|Drosik, A|Giglok, M|Suwinski, R|Rusin, M
PMID: 25742468
Journal: Oncol Lett. 2017 Aug;14(2):1875-1883.
Title: Wip1 gene silencing enhances the chemosensitivity of human colon cancer cells.
Author: Xia, Zhong-Sheng|Wu, Di|Zhong, Wa|Lu, Xi-Ji|Yu, Tao|Chen, Qi-Kui
PMID: 28781635
Journal: Biomed Pharmacother. 2018 Mar;99:402-410.
Title: NF-kappaB-induced WIP1 expression promotes colorectal cancer cell proliferation through mTOR signaling.
Author: Bai, Fei|Zhou, Huijun|Fu, Zhongping|Xie, Jiangbo|Hu, Yingbin|Nie, Shaolin
PMID: 29367109