Primary Site >> Colorectal Cancer
Gene >> PPARG
| 1. | |||||||||||
| Journal: | Carcinogenesis. 1998 Jan;19(1):49-53. | ||||||||||
| Title: | The nuclear eicosanoid receptor, PPARgamma, is aberrantly expressed in colonic cancers. | ||||||||||
| Author: | DuBois, R N|Gupta, R|Brockman, J|Reddy, B S|Krakow, S L|Lazar, M A | ||||||||||
| PMID: | 9472692 | ||||||||||
| 2. | |||||||||||
| Journal: | Nat Med. 1998 Sep;4(9):1004-5. | ||||||||||
| Title: | PPARgamma and colorectal carcinoma: conflicts in a nuclear family. | ||||||||||
| Author: | Seed, B | ||||||||||
| PMID: | 9734386 | ||||||||||
| 3. | |||||||||||
| Journal: | Nat Med. 1998 Sep;4(9):1046-52. | ||||||||||
| Title: | Differentiation and reversal of malignant changes in colon cancer through PPARgamma. | ||||||||||
| Author: | Sarraf, P|Mueller, E|Jones, D|King, F J|DeAngelo, D J|Partridge, J B|Holden, S A|Chen, L B|Singer, S|Fletcher, C|Spiegelman, B M | ||||||||||
| PMID: | 9734398 | ||||||||||
| 4. | |||||||||||
| Journal: | Nat Med. 1998 Sep;4(9):1053-7. | ||||||||||
| Title: | Activation of the peroxisome proliferator-activated receptor gamma promotes the development of colon tumors in C57BL/6J-APCMin/+ mice. | ||||||||||
| Author: | Lefebvre, A M|Chen, I|Desreumaux, P|Najib, J|Fruchart, J C|Geboes, K|Briggs, M|Heyman, R|Auwerx, J | ||||||||||
| PMID: | 9734399 | ||||||||||
| 5. | |||||||||||
| Journal: | Gastroenterology. 1998 Nov;115(5):1049-55. | ||||||||||
| Title: | Activation of PPARgamma leads to inhibition of anchorage-independent growth of human colorectal cancer cells. | ||||||||||
| Author: | Brockman, J A|Gupta, R A|Dubois, R N | ||||||||||
| PMID: | 9797355 | ||||||||||
| 6. | |||||||||||
| Journal: | Cancer Res. 2000 Feb 15;60(4):1129-38. | ||||||||||
| Title: | Induction of differentiation and apoptosis by ligands of peroxisome proliferator-activated receptor gamma in non-small cell lung cancer. | ||||||||||
| Author: | Chang, T H|Szabo, E | ||||||||||
| PMID: | 10706135 | ||||||||||
| 7. | |||||||||||
| Journal: | Immunol Cell Biol. 2000 Aug;78(4):436-41. | ||||||||||
| Title: | Peroxisome proliferator-activated receptors in tumorigenesis: targets of tumour promotion and treatment. | ||||||||||
| Author: | Roberts-Thomson, S J | ||||||||||
| PMID: | 10947870 | ||||||||||
| 8. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 2000 Sep 26;97(20):10990-5. | ||||||||||
| Title: | Effects of ligand activation of peroxisome proliferator-activated receptor gamma in human prostate cancer. | ||||||||||
| Author: | Mueller, E|Smith, M|Sarraf, P|Kroll, T|Aiyer, A|Kaufman, D S|Oh, W|Demetri, G|Figg, W D|Zhou, X P|Eng, C|Spiegelman, B M|Kantoff, P W | ||||||||||
| PMID: | 10984506 | ||||||||||
| 9. | |||||||||||
| Journal: | Br J Cancer. 2000 Nov;83(10):1394-400. | ||||||||||
| Title: | Expression of peroxisome proliferator-activated receptor (PPAR)gamma in gastric cancer and inhibitory effects of PPARgamma agonists. | ||||||||||
| Author: | Sato, H|Ishihara, S|Kawashima, K|Moriyama, N|Suetsugu, H|Kazumori, H|Okuyama, T|Rumi, M A|Fukuda, R|Nagasue, N|Kinoshita, Y | ||||||||||
| PMID: | 11044367 | ||||||||||
| 10. | |||||||||||
| Journal: | Adv Drug Deliv Rev. 2000 Dec 6;45(1):65-75. | ||||||||||
| Title: | Preparation and evaluation of o/w type emulsions containing antitumor prostaglandin. | ||||||||||
| Author: | Fukushima, S|Kishimoto, S|Takeuchi, Y|Fukushima, M | ||||||||||
| PMID: | 11104898 | ||||||||||
| 11. | |||||||||||
| Journal: | Cancer Res. 2001 Mar 15;61(6):2424-8. | ||||||||||
| Title: | Ligands for peroxisome proliferator-activated receptors alpha and gamma inhibit chemically induced colitis and formation of aberrant crypt foci in rats. | ||||||||||
| Author: | Tanaka, T|Kohno, H|Yoshitani, S|Takashima, S|Okumura, A|Murakami, A|Hosokawa, M | ||||||||||
| PMID: | 11289109 | ||||||||||
| 12. | |||||||||||
| Journal: | Jpn J Cancer Res. 2001 Apr;92(4):396-403. | ||||||||||
| Title: | Troglitazone, a ligand for peroxisome proliferator-activated receptor gamma, inhibits chemically-induced aberrant crypt foci in rats. | ||||||||||
| Author: | Kohno, H|Yoshitani , S|Takashima, S|Okumura, A|Hosokawa, M|Yamaguchi, N|Tanaka, T | ||||||||||
| PMID: | 11346461 | ||||||||||
| 13. | |||||||||||
| Journal: | Curr Biol. 2001 May 15;11(10):764-8. | ||||||||||
| Title: | Tumor suppressor and anti-inflammatory actions of PPARgamma agonists are mediated via upregulation of PTEN. | ||||||||||
| Author: | Patel, L|Pass, I|Coxon, P|Downes, C P|Smith, S A|Macphee, C H | ||||||||||
| PMID: | 11378386 | ||||||||||
| 14. | |||||||||||
| Journal: | J Biol Chem. 2001 Aug 10;276(32):29681-7. | ||||||||||
| Title: | Target genes of peroxisome proliferator-activated receptor gamma in colorectal cancer cells. | ||||||||||
| Author: | Gupta, R A|Brockman, J A|Sarraf, P|Willson, T M|DuBois, R N | ||||||||||
| PMID: | 11397807 | ||||||||||
| 15. | |||||||||||
| Journal: | Exp Cell Res. 2001 Jul 1;267(1):73-80. | ||||||||||
| Title: | Effect of PPAR activators on cytokine-stimulated cyclooxygenase-2 expression in human colorectal carcinoma cells. | ||||||||||
| Author: | Ikawa, H|Kameda, H|Kamitani, H|Baek, S J|Nixon, J B|Hsi, L C|Eling, T E | ||||||||||
| PMID: | 11412039 | ||||||||||
| 16. | |||||||||||
| Journal: | Cancer Res. 2001 Jul 1;61(13):5307-10. | ||||||||||
| Title: | Mutational analysis of the peroxisome proliferator-activated receptor gamma gene in human malignancies. | ||||||||||
| Author: | Ikezoe, T|Miller, C W|Kawano, S|Heaney, A|Williamson, E A|Hisatake, J|Green, E|Hofmann, W|Taguchi, H|Koeffler, H P | ||||||||||
| PMID: | 11431375 | ||||||||||
| 17. | |||||||||||
| Journal: | J Biol Chem. 2001 Sep 14;276(37):34545-52. | ||||||||||
| Title: | 15-lipoxygenase-1 metabolites down-regulate peroxisome proliferator-activated receptor gamma via the MAPK signaling pathway. | ||||||||||
| Author: | Hsi, L C|Wilson, L|Nixon, J|Eling, T E | ||||||||||
| PMID: | 11447213 | ||||||||||
| 18. | |||||||||||
| Journal: | Hum Genet. 2001 Aug;109(2):146-51. | ||||||||||
| Title: | Opposite association of two PPARG variants with cancer: overrepresentation of H449H in endometrial carcinoma cases and underrepresentation of P12A in renal cell carcinoma cases. | ||||||||||
| Author: | Smith, W M|Zhou, X P|Kurose, K|Gao, X|Latif, F|Kroll, T|Sugano, K|Cannistra, S A|Clinton, S K|Maher, E R|Prior, T W|Eng, C | ||||||||||
| PMID: | 11511919 | ||||||||||
| 19. | |||||||||||
| Journal: | Carcinogenesis. 2001 Sep;22(9):1379-83. | ||||||||||
| Title: | Activation of the PPAR pathway induces apoptosis and COX-2 inhibition in HT-29 human colon cancer cells. | ||||||||||
| Author: | Yang, W L|Frucht, H | ||||||||||
| PMID: | 11532858 | ||||||||||
| 20. | |||||||||||
| Journal: | Int J Oncol. 2001 Dec;19(6):1179-86. | ||||||||||
| Title: | Expression of putative anticancer targets in familial adenomatous polyposis and its association with the APC mutation status. | ||||||||||
| Author: | Humar, B|D'Orazio, D|Albrecht, C|Bauerfeind, P|Muller, H|Dobbie, Z|Bendik, I | ||||||||||
| PMID: | 11713587 | ||||||||||
| 21. | |||||||||||
| Journal: | Am J Pathol. 2002 Feb;160(2):389-401. | ||||||||||
| Title: | Beta-catenin--a linchpin in colorectal carcinogenesis? | ||||||||||
| Author: | Wong, Newton Alexander Chiang Shuek|Pignatelli, Massimo | ||||||||||
| PMID: | 11839557 | ||||||||||
| 22. | |||||||||||
| Journal: | Gut. 2002 May;50(5):658-64. | ||||||||||
| Title: | Characteristics of the peroxisome proliferator activated receptor gamma (PPARgamma) ligand induced apoptosis in colon cancer cells. | ||||||||||
| Author: | Shimada, T|Kojima, K|Yoshiura, K|Hiraishi, H|Terano, A | ||||||||||
| PMID: | 11950812 | ||||||||||
| 23. | |||||||||||
| Journal: | Int J Mol Med. 2002 May;9(5):485-8. | ||||||||||
| Title: | Frequent polymorphism of peroxisome proliferator activated receptor gamma gene in colorectal cancer containing wild-type K-ras gene. | ||||||||||
| Author: | Tomita, Shigeki|Kawamata, Hitoshi|Imura, Johji|Omotehara, Fumie|Ueda, Yoshihiko|Fujimori, Takahiro | ||||||||||
| PMID: | 11956653 | ||||||||||
| 24. | |||||||||||
| Journal: | Biol Cell. 2002 Feb;94(1):15-27. | ||||||||||
| Title: | Expression of peroxisome proliferator-activated receptors alpha and gamma in differentiating human colon carcinoma Caco-2 cells. | ||||||||||
| Author: | Huin, Cecile|Schohn, Herve|Hatier, Renee|Bentejac, Marc|Antunes, Laurent|Plenat, Francois|Bugaut, Maurice|Dauca, Michel | ||||||||||
| PMID: | 12000143 | ||||||||||
| 25. | |||||||||||
| Journal: | Surg Today. 2002;32(4):343-50. | ||||||||||
| Title: | Decreased synthesis of matrix metalloproteinase-7 and adhesion to the extracellular matrix proteins of human colon cancer cells treated with troglitazone. | ||||||||||
| Author: | Sunami, Eiji|Tsuno, Nelson Hirokazu|Kitayama, Joji|Saito, Shinsuke|Osada, Takuya|Yamaguchi, Hironori|Tomozawa, Shigeru|Tsuruo, Takashi|Shibata, Yoichi|Nagawa, Hirokazu | ||||||||||
| PMID: | 12027200 | ||||||||||
| 26. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2002 May 3;293(2):827-31. | ||||||||||
| Title: | Butyrate reduces colonic paracellular permeability by enhancing PPARgamma activation. | ||||||||||
| Author: | Kinoshita, Mako|Suzuki, Yasuo|Saito, Yasushi | ||||||||||
| PMID: | 12054544 | ||||||||||
| 27. | |||||||||||
| Journal: | Am J Physiol Gastrointest Liver Physiol. 2002 Aug;283(2):G266-9. | ||||||||||
| Title: | Controversy: PPARgamma as a target for treatment of colorectal cancer. | ||||||||||
| Author: | Gupta, Rajnish A|Dubois, Raymond N | ||||||||||
| PMID: | 12121872 | ||||||||||
| 28. | |||||||||||
| Journal: | J Biol Chem. 2002 Oct 25;277(43):40549-56. Epub 2002 Aug 19. | ||||||||||
| Title: | Opposing effects of 15-lipoxygenase-1 and -2 metabolites on MAPK signaling in prostate. Alteration in peroxisome proliferator-activated receptor gamma. | ||||||||||
| Author: | Hsi, Linda C|Wilson, Leigh C|Eling, Thomas E | ||||||||||
| PMID: | 12189136 | ||||||||||
| 29. | |||||||||||
| Journal: | Life Sci. 2002 Apr 19;70(22):2631-46. | ||||||||||
| Title: | Apoptosis induced by activation of peroxisome-proliferator activated receptor-gamma is associated with Bcl-2 and NF-kappaB in human colon cancer. | ||||||||||
| Author: | Chen, George G|Lee, Janet F Y|Wang, Su H|Chan, Ursula P F|Ip, Ping C|Lau, Wan Y | ||||||||||
| PMID: | 12269390 | ||||||||||
| 30. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13771-6. Epub 2002 Oct 7. | ||||||||||
| Title: | APC-dependent suppression of colon carcinogenesis by PPARgamma. | ||||||||||
| Author: | Girnun, Geoffrey D|Smith, Wendy M|Drori, Stavit|Sarraf, Pasha|Mueller, Elisabetta|Eng, Charis|Nambiar, Prashant|Rosenberg, Daniel W|Bronson, Roderick T|Edelmann, Winfried|Kucherlapati, Raju|Gonzalez, Frank J|Spiegelman, Bruce M | ||||||||||
| PMID: | 12370429 | ||||||||||
| 31. | |||||||||||
| Journal: | Cancer J. 2002 Sep-Oct;8(5):395-9. | ||||||||||
| Title: | A phase II study of troglitazone, an activator of the PPARgamma receptor, in patients with chemotherapy-resistant metastatic colorectal cancer. | ||||||||||
| Author: | Kulke, Matthew H|Demetri, George D|Sharpless, Norman E|Ryan, David P|Shivdasani, Ramesh|Clark, Jeffrey S|Spiegelman, Bruce M|Kim, Haesook|Mayer, Robert J|Fuchs, Charles S | ||||||||||
| PMID: | 12416897 | ||||||||||
| 32. | |||||||||||
| Journal: | Ann N Y Acad Sci. 2002 Nov;973:241-5. | ||||||||||
| Title: | The role of mitogen-activated protein kinases and their relationship with NF-kappaB and PPARgamma in indomethacin-Induced apoptosis of colon cancer cells. | ||||||||||
| Author: | Kim, Tae Il|Jin, Soo Hyun|Kang, Eun Hye|Shin, Sung Kwan|Choi, Kang Yell|Kim, Won Ho | ||||||||||
| PMID: | 12485869 | ||||||||||
| 33. | |||||||||||
| Journal: | Mol Cancer Ther. 2002 Mar;1(5):357-63. | ||||||||||
| Title: | Peroxisome proliferator-activated receptor modulators as potential chemopreventive agents. | ||||||||||
| Author: | Kopelovich, Levy|Fay, Judith R|Glazer, Robert I|Crowell, James A | ||||||||||
| PMID: | 12489852 | ||||||||||
| 34. | |||||||||||
| Journal: | Gastroenterology. 2003 Feb;124(2):361-7. | ||||||||||
| Title: | Peroxisome proliferator-activated receptor gamma ligands suppress colon carcinogenesis induced by azoxymethane in mice. | ||||||||||
| Author: | Osawa, Emi|Nakajima, Atsushi|Wada, Koichiro|Ishimine, Satoko|Fujisawa, Nobutaka|Kawamori, Toshihiko|Matsuhashi, Nobuyuki|Kadowaki, Takashi|Ochiai, Masako|Sekihara, Hisahiko|Nakagama, Hitoshi | ||||||||||
| PMID: | 12557142 | ||||||||||
| 35. | |||||||||||
| Journal: | Am J Prev Med. 2003 Feb;24(2):170-6. | ||||||||||
| Title: | Family history of colon cancer: what does it mean and how is it useful? | ||||||||||
| Author: | Keku, Temitope O|Millikan, Robert C|Martin, Chris|Rahkra-Burris, Tejinder K|Sandler, Robert S | ||||||||||
| PMID: | 12568823 | ||||||||||
| 36. | |||||||||||
| Journal: | J Biol Chem. 2003 Jun 20;278(25):22669-77. | ||||||||||
| Title: | Peroxisome proliferator-activated receptor gamma-mediated differentiation: a mutation in colon cancer cells reveals divergent and cell type-specific mechanisms. | ||||||||||
| Author: | Gupta, Rajnish A|Sarraf, Pasha|Mueller, Elisabetta|Brockman, Jeffrey A|Prusakiewicz, Jeffery J|Eng, Charis|Willson, Timothy M|DuBois, Raymond N | ||||||||||
| PMID: | 12591919 | ||||||||||
| 37. | |||||||||||
| Journal: | J Pharmacol Exp Ther. 2003 May;305(2):632-7. | ||||||||||
| Title: | Activation of peroxisome proliferator-activated receptor gamma does not explain the antiproliferative activity of the nonsteroidal anti-inflammatory drug indomethacin on human colorectal cancer cells. | ||||||||||
| Author: | Hawcroft, G|Gardner, S H|Hull, M A | ||||||||||
| PMID: | 12606626 | ||||||||||
| 38. | |||||||||||
| Journal: | Comp Hepatol. 2003 Jan 31;2(1):3. | ||||||||||
| Title: | Advances in understanding the regulation of apoptosis and mitosis by peroxisome-proliferator activated receptors in pre-clinical models: relevance for human health and disease. | ||||||||||
| Author: | Boitier, Eric|Gautier, Jean-Charles|Roberts, Ruth | ||||||||||
| PMID: | 12622871 | ||||||||||
| 39. | |||||||||||
| Journal: | Biochem Soc Trans. 2003 Apr;31(2):388-92. | ||||||||||
| Title: | Polyamines as modifiers of genetic risk factors in human intestinal cancers. | ||||||||||
| Author: | Babbar, N|Gerner, E W | ||||||||||
| PMID: | 12653645 | ||||||||||
| 40. | |||||||||||
| Journal: | Prostaglandins Leukot Essent Fatty Acids. 2003 May;68(5):323-30. | ||||||||||
| Title: | Evaluation of eicosanoids and NSAIDs as PPARgamma ligands in colorectal carcinoma cells. | ||||||||||
| Author: | Nixon, J B|Kamitani, H|Baek, S J|Eling, T E | ||||||||||
| PMID: | 12711249 | ||||||||||
| 41. | |||||||||||
| Journal: | Breast Cancer Res Treat. 2003 Mar;78(2):179-92. | ||||||||||
| Title: | The antiproliferative effects of PPARgamma ligands in normal human mammary epithelial cells. | ||||||||||
| Author: | Yee, Lisa D|Guo, Yan|Bradbury, Jamie|Suster, Saul|Clinton, Steven K|Seewaldt, Victoria L | ||||||||||
| PMID: | 12725418 | ||||||||||
| 42. | |||||||||||
| Journal: | Oncogene. 2003 Jun 19;22(25):3888-900. | ||||||||||
| Title: | Peroxisome proliferator-activated receptor-gamma upregulates caveolin-1 and caveolin-2 expression in human carcinoma cells. | ||||||||||
| Author: | Burgermeister, Elke|Tencer, Lilach|Liscovitch, Mordechai | ||||||||||
| PMID: | 12813462 | ||||||||||
| 43. | |||||||||||
| Journal: | Cancer Res. 2003 Jul 1;63(13):3560-6. | ||||||||||
| Title: | Association of common polymorphisms in inflammatory genes interleukin (IL)6, IL8, tumor necrosis factor alpha, NFKB1, and peroxisome proliferator-activated receptor gamma with colorectal cancer. | ||||||||||
| Author: | Landi, Stefano|Moreno, Victor|Gioia-Patricola, Lydie|Guino, Elisabeth|Navarro, Matilde|de Oca, Javier|Capella, Gabriel|Canzian, Federico | ||||||||||
| PMID: | 12839942 | ||||||||||
| 44. | |||||||||||
| Journal: | Gastroenterology. 2003 Aug;125(2):619-21. | ||||||||||
| Title: | The role of PPARgamma in colon cancer: is it as simple as APC? | ||||||||||
| Author: | Peek, Richard M Jr | ||||||||||
| PMID: | 12891569 | ||||||||||
| 45. | |||||||||||
| Journal: | BMC Cancer. 2003 Oct 1;3:25. | ||||||||||
| Title: | Gamma (gamma) tocopherol upregulates peroxisome proliferator activated receptor (PPAR) gamma (gamma) expression in SW 480 human colon cancer cell lines. | ||||||||||
| Author: | Campbell, Sharon E|Stone, William L|Whaley, Sarah G|Qui, Min|Krishnan, Koyamangalath | ||||||||||
| PMID: | 14521714 | ||||||||||
| 46. | |||||||||||
| Journal: | Cancer Res. 2003 Sep 15;63(18):6090-5. | ||||||||||
| Title: | Concomitant suppression of hyperlipidemia and intestinal polyp formation in Apc-deficient mice by peroxisome proliferator-activated receptor ligands. | ||||||||||
| Author: | Niho, Naoko|Takahashi, Mami|Kitamura, Tomohiro|Shoji, Yutaka|Itoh, Masaki|Noda, Tetsuo|Sugimura, Takashi|Wakabayashi, Keiji | ||||||||||
| PMID: | 14522940 | ||||||||||
| 47. | |||||||||||
| Journal: | Int J Cancer. 2003 Dec 10;107(5):837-43. | ||||||||||
| Title: | 15-hydroxy-eicosatetraenoic acid arrests growth of colorectal cancer cells via a peroxisome proliferator-activated receptor gamma-dependent pathway. | ||||||||||
| Author: | Chen, George G|Xu, Hu|Lee, Janet F Y|Subramaniam, Malayannan|Leung, Ka L|Wang, Su H|Chan, Ursula P F|Spelsberg, Thomas C | ||||||||||
| PMID: | 14566836 | ||||||||||
| 48. | |||||||||||
| Journal: | J Cell Biochem. 2003 Nov 1;90(4):732-44. | ||||||||||
| Title: | Phosphorylation of PPARgamma via active ERK1/2 leads to its physical association with p65 and inhibition of NF-kappabeta. | ||||||||||
| Author: | Chen, Fei|Wang, Muchun|O'Connor, J Patrick|He, Mai|Tripathi, Tushar|Harrison, Lawrence E | ||||||||||
| PMID: | 14587029 | ||||||||||
| 49. | |||||||||||
| Journal: | Endocr Regul. 2003 Sep;37(3):137-44. | ||||||||||
| Title: | Hyperlipidic diets induce early alterations of the vitamin A signalling pathway in rat colonic mucosa. | ||||||||||
| Author: | Groubet, R|Pallet, V|Delage, B|Redonnet, A|Higueret, P|Cassand, P | ||||||||||
| PMID: | 14986719 | ||||||||||
| 50. | |||||||||||
| Journal: | J Endocrinol Invest. 2003 Nov;26(11):1054-8. | ||||||||||
| Title: | Colonic polyps of acromegalic patients are not associated with mutations of the peroxisome proliferator activated receptor gamma gene. | ||||||||||
| Author: | Bogazzi, F|Ultimieri, F|Raggi, F|Russo, D|Brogioni, S|Cosci, C|Gasperi, M|Costa, A|Viacava, P|Mosca, F|Bartalena, L|Martino, E | ||||||||||
| PMID: | 15008240 | ||||||||||
| 51. | |||||||||||
| Journal: | J Cancer Res Clin Oncol. 2004 Feb;130(2):73-9. Epub 2003 Nov 21. | ||||||||||
| Title: | Induction of differentiation and peroxisome proliferator-activated receptor gamma expression in colon cancer cell lines by troglitazone. | ||||||||||
| Author: | Kato, Masashi|Kusumi, Tomomi|Tsuchida, Shigeki|Tanaka, Masanori|Sasaki, Mutsuo|Kudo, Hajime | ||||||||||
| PMID: | 14634802 | ||||||||||
| 52. | |||||||||||
| Journal: | J Biol Chem. 2004 Feb 20;279(8):6883-92. Epub 2003 Dec 8. | ||||||||||
| Title: | Expression of NAG-1, a transforming growth factor-beta superfamily member, by troglitazone requires the early growth response gene EGR-1. | ||||||||||
| Author: | Baek, Seung Joon|Kim, Jong-Sik|Nixon, Jennifer B|DiAugustine, Richard P|Eling, Thomas E | ||||||||||
| PMID: | 14662774 | ||||||||||
| 53. | |||||||||||
| Journal: | Cancer Lett. 2004 Jan 8;203(1):25-33. | ||||||||||
| Title: | Peroxisome proliferator-activated receptors (PPARs) and associated transcription factors in colon cancer: reduced expression of PPARgamma-coactivator 1 (PGC-1). | ||||||||||
| Author: | Feilchenfeldt, Jonas|Brundler, Marie Anne|Soravia, Claudio|Totsch, Martin|Meier, Christoph A | ||||||||||
| PMID: | 14670614 | ||||||||||
| 54. | |||||||||||
| Journal: | Toxicol Pathol. 2004 Jan-Feb;32(1):58-63. | ||||||||||
| Title: | Promotion of colon tumors in C57BL/6J-APC(min)/+ mice by thiazolidinedione PPARgamma agonists and a structurally unrelated PPARgamma agonist. | ||||||||||
| Author: | Pino, Michael V|Kelley, Michael F|Jayyosi, Zaid | ||||||||||
| PMID: | 14713549 | ||||||||||
| 55. | |||||||||||
| Journal: | Mol Carcinog. 2004 Feb;39(2):91-102. | ||||||||||
| Title: | Suppression of polyamine catabolism by activated Ki-ras in human colon cancer cells. | ||||||||||
| Author: | Ignatenko, Natalia A|Babbar, Naveen|Mehta, Dipti|Casero, Robert A Jr|Gerner, Eugene W | ||||||||||
| PMID: | 14750214 | ||||||||||
| 56. | |||||||||||
| Journal: | Carcinogenesis. 2004 Sep;25(9):1747-55. Epub 2004 Apr 8. | ||||||||||
| Title: | PPARgamma influences susceptibility to DMBA-induced mammary, ovarian and skin carcinogenesis. | ||||||||||
| Author: | Nicol, Christopher J|Yoon, Michung|Ward, Jerrold M|Yamashita, Masamichi|Fukamachi, Katsumi|Peters, Jeffrey M|Gonzalez, Frank J | ||||||||||
| PMID: | 15073042 | ||||||||||
| 57. | |||||||||||
| Journal: | Cancer Lett. 2004 Jul 8;210(1):7-15. | ||||||||||
| Title: | Limited tumor growth (HT29) in vivo under RO205-2349 is due to increased apoptosis and reduced cell volume but not to decreased proliferation rate. | ||||||||||
| Author: | Katoh, Marcus|Feldhaus, Susanne|Schnitzer, Tobias|Bauer, Sabine|Schumacher, Udo | ||||||||||
| PMID: | 15172115 | ||||||||||
| 58. | |||||||||||
| Journal: | Regul Pept. 2004 Aug 15;120(1-3):243-51. | ||||||||||
| Title: | PPARalpha agonists stimulate progastrin production in human colorectal carcinoma cells. | ||||||||||
| Author: | Lachal, Shamilah|Ford, Joanne|Shulkes, Arthur|Baldwin, Graham S | ||||||||||
| PMID: | 15177943 | ||||||||||
| 59. | |||||||||||
| Journal: | Cancer Sci. 2004 Jun;95(6):481-6. | ||||||||||
| Title: | Pomegranate seed oil rich in conjugated linolenic acid suppresses chemically induced colon carcinogenesis in rats. | ||||||||||
| Author: | Kohno, Hiroyuki|Suzuki, Rikako|Yasui, Yumiko|Hosokawa, Masashi|Miyashita, Kazuo|Tanaka, Takuji | ||||||||||
| PMID: | 15182427 | ||||||||||
| 60. | |||||||||||
| Journal: | Biol Chem. 2004 Jun;385(6):449-64. | ||||||||||
| Title: | Colon cancer: genomics and apoptotic events. | ||||||||||
| Author: | Rupnarain, Charleen|Dlamini, Zodwa|Naicker, Sarala|Bhoola, Kanti | ||||||||||
| PMID: | 15255176 | ||||||||||
| 61. | |||||||||||
| Journal: | Cancer Res. 2004 Aug 1;64(15):5162-71. | ||||||||||
| Title: | Inhibition of activator protein 1 activation, vascular endothelial growth factor, and cyclooxygenase-2 expression by 15-deoxy-Delta12,14-prostaglandin J2 in colon carcinoma cells: evidence for a redox-sensitive peroxisome proliferator-activated receptor-g | ||||||||||
| Author: | Grau, Raquel|Iniguez, Miguel A|Fresno, Manuel | ||||||||||
| PMID: | 15289320 | ||||||||||
| 62. | |||||||||||
| Journal: | Int J Oncol. 2004 Sep;25(3):631-9. | ||||||||||
| Title: | Thiazolidinedione, a peroxisome proliferator-activated receptor-gamma ligand, inhibits growth and metastasis of HT-29 human colon cancer cells through differentiation-promoting effects. | ||||||||||
| Author: | Yoshizumi, Tetsuya|Ohta, Tetsuo|Ninomiya, Itasu|Terada, Itsuro|Fushida, Sachio|Fujimura, Takashi|Nishimura, Gen-Ichi|Shimizu, Koichi|Yi, Shuangqin|Miwa, Koichi | ||||||||||
| PMID: | 15289864 | ||||||||||
| 63. | |||||||||||
| Journal: | Curr Pharm Des. 2004;10(22):2779-86. | ||||||||||
| Title: | Pleiotropic actions of PPAR gamma activators thiazolidinediones in cardiovascular diseases. | ||||||||||
| Author: | Takano, Hiroyuki|Hasegawa, Hiroshi|Zou, Yunzeng|Komuro, Issei | ||||||||||
| PMID: | 15320743 | ||||||||||
| 64. | |||||||||||
| Journal: | Cancer Res. 2004 Sep 1;64(17):5994-6001. | ||||||||||
| Title: | 1,1-Bis(3'-indolyl)-1-(p-substitutedphenyl)methanes induce peroxisome proliferator-activated receptor gamma-mediated growth inhibition, transactivation, and differentiation markers in colon cancer cells. | ||||||||||
| Author: | Chintharlapalli, Sudhakar|Smith, Roger 3rd|Samudio, Ismael|Zhang, Wei|Safe, Stephen | ||||||||||
| PMID: | 15342379 | ||||||||||
| 65. | |||||||||||
| Journal: | J Med Food. 2004 Fall;7(3):267-73. | ||||||||||
| Title: | Capsaicin, a spicy component of hot pepper, induces apoptosis by activation of the peroxisome proliferator-activated receptor gamma in HT-29 human colon cancer cells. | ||||||||||
| Author: | Kim, Chu-Sook|Park, Won-Hyung|Park, Jun-Young|Kang, Ji-Hye|Kim, Mi-Ock|Kawada, Teruo|Yoo, Hoon|Han, In-Seob|Yu, Rina | ||||||||||
| PMID: | 15383218 | ||||||||||
| 66. | |||||||||||
| Journal: | Biochim Biophys Acta. 2004 Nov 18;1675(1-3):113-9. | ||||||||||
| Title: | Fucoxanthin induces apoptosis and enhances the antiproliferative effect of the PPARgamma ligand, troglitazone, on colon cancer cells. | ||||||||||
| Author: | Hosokawa, Masashi|Kudo, Masahiro|Maeda, Hayato|Kohno, Hiroyuki|Tanaka, Takuji|Miyashita, Kazuo | ||||||||||
| PMID: | 15535974 | ||||||||||
| 67. | |||||||||||
| Journal: | Ann N Y Acad Sci. 2004 Dec;1031:223-33. | ||||||||||
| Title: | Tocopherols and the treatment of colon cancer. | ||||||||||
| Author: | Stone, William L|Krishnan, Koyamangalath|Campbell, Sharon E|Qui, Min|Whaley, Sarah G|Yang, Hongsong | ||||||||||
| PMID: | 15753148 | ||||||||||
| 68. | |||||||||||
| Journal: | Am J Physiol Gastrointest Liver Physiol. 2005 Mar;288(3):G447-56. Epub 2004 Oct | ||||||||||
| Title: | Activation of PPAR{gamma} by curcumin inhibits Moser cell growth and mediates suppression of gene expression of cyclin D1 and EGFR. | ||||||||||
| Author: | Chen, Anping|Xu, Jianye | ||||||||||
| PMID: | 15486348 | ||||||||||
| 69. | |||||||||||
| Journal: | Carcinogenesis. 2005 Mar;26(3):579-85. | ||||||||||
| Title: | The PPAR{gamma} Pro12Ala polymorphism and risk for incident sporadic colorectal adenomas. | ||||||||||
| Author: | Gong, Zhihong|Xie, Dawen|Deng, Zonglin|Bostick, Roberd M|Muga, Stephanie J|Hurley, Thomas G|Hebert, James R | ||||||||||
| PMID: | 15564289 | ||||||||||
| 70. | |||||||||||
| Journal: | Int J Biochem Cell Biol. 2005 Mar;37(3):645-54. | ||||||||||
| Title: | Ciglitazone induces early cellular proliferation and NF-kappaB transcriptional activity in colon cancer cells through p65 phosphorylation. | ||||||||||
| Author: | Chen, Fei|Harrison, Lawrence E | ||||||||||
| PMID: | 15618021 | ||||||||||
| 71. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1460-5. Epub 2005 Jan 21. | ||||||||||
| Title: | The Wnt/beta-catenin signaling pathway targets PPARgamma activity in colon cancer cells. | ||||||||||
| Author: | Jansson, Emmelie A|Are, Alexandra|Greicius, Gediminas|Kuo, I-Chun|Kelly, Denise|Arulampalam, Velmurugesan|Pettersson, Sven | ||||||||||
| PMID: | 15665104 | ||||||||||
| 72. | |||||||||||
| Journal: | Genes Dev. 2005 Feb 1;19(3):362-75. | ||||||||||
| Title: | Hic-5 regulates an epithelial program mediated by PPARgamma. | ||||||||||
| Author: | Drori, Stavit|Girnun, Geoffrey D|Tou, Liqiang|Szwaya, Jeffrey D|Mueller, Elisabetta|Xia, Kai|Shivdasani, Ramesh A|Spiegelman, Bruce M | ||||||||||
| PMID: | 15687259 | ||||||||||
| 73. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 2005 Feb 22;102(8):2970-4. | ||||||||||
| Title: | Concurrent suppression of hyperlipidemia and intestinal polyp formation by NO-1886, increasing lipoprotein lipase activity in Min mice. | ||||||||||
| Author: | Niho, Naoko|Mutoh, Michihiro|Takahashi, Mami|Tsutsumi, Kazuhiko|Sugimura, Takashi|Wakabayashi, Keiji | ||||||||||
| PMID: | 15710887 | ||||||||||
| 74. | |||||||||||
| Journal: | Clin Cancer Res. 2005 Feb 15;11(4):1400-7. | ||||||||||
| Title: | Alteration of gene expression in macroscopically normal colonic mucosa from individuals with a family history of sporadic colon cancer. | ||||||||||
| Author: | Hao, Chun-Yi|Moore, Dan H|Wong, Patrick|Bennington, James L|Lee, Nancy M|Chen, Ling-Chun | ||||||||||
| PMID: | 15746039 | ||||||||||
| 75. | |||||||||||
| Journal: | Cell Signal. 2005 Jul;17(7):809-16. Epub 2004 Nov 24. | ||||||||||
| Title: | Ciglitazone-induced cellular anti-proliferation increases p27kip1 protein levels through both increased transcriptional activity and inhibition of proteasome degradation. | ||||||||||
| Author: | Chen, Fei|Harrison, Lawrence E | ||||||||||
| PMID: | 15763423 | ||||||||||
| 76. | |||||||||||
| Journal: | Mol Pharmacol. 2005 Jul;68(1):119-28. | ||||||||||
| Title: | 2-Cyano-3,12-dioxoolean-1,9-dien-28-oic acid and related compounds inhibit growth of colon cancer cells through peroxisome proliferator-activated receptor gamma-dependent and -independent pathways. | ||||||||||
| Author: | Chintharlapalli, Sudhakar|Papineni, Sabitha|Konopleva, Marina|Andreef, Michael|Samudio, Ismael|Safe, Stephen | ||||||||||
| PMID: | 15798084 | ||||||||||
| 77. | |||||||||||
| Journal: | Nihon Rinsho. 2005 Apr;63(4):665-71. | ||||||||||
| Title: | [The roles of PPARs in digestive diseases]. | ||||||||||
| Author: | Nakajima, Atsushi|Yoneda, Masato|Takahashi, Hirokazu|Fujisawa, Nobutaka|Wada, Koichiro | ||||||||||
| PMID: | 15828235 | ||||||||||
| 78. | |||||||||||
| Journal: | J Biol Chem. 2005 Jul 15;280(28):26517-25. Epub 2005 Apr 27. | ||||||||||
| Title: | A novel peroxisome proliferator-activated receptor gamma isoform with dominant negative activity generated by alternative splicing. | ||||||||||
| Author: | Sabatino, Lina|Casamassimi, Amelia|Peluso, Gianfranco|Barone, Maria Vittoria|Capaccio, Daniela|Migliore, Chiara|Bonelli, Patrizia|Pedicini, Antonio|Febbraro, Antonio|Ciccodicola, Alfredo|Colantuoni, Vittorio | ||||||||||
| PMID: | 15857827 | ||||||||||
| 79. | |||||||||||
| Journal: | Nutr Cancer. 2005;51(2):155-61. | ||||||||||
| Title: | PPARgamma, energy balance, and associations with colon and rectal cancer. | ||||||||||
| Author: | Slattery, Martha L|Murtaugh, Maureen A|Sweeney, Carol|Ma, Khe-Ni|Potter, John D|Caan, Bette J|Samowitz, Wade | ||||||||||
| PMID: | 15860437 | ||||||||||
| 80. | |||||||||||
| Journal: | Mol Cell Endocrinol. 2005 May 12;235(1-2):21-9. Epub 2005 Mar 16. | ||||||||||
| Title: | Selective activation of PPARgamma in breast, colon, and lung cancer cell lines. | ||||||||||
| Author: | Allred, Clinton D|Kilgore, Michael W | ||||||||||
| PMID: | 15866424 | ||||||||||
| 81. | |||||||||||
| Journal: | BMC Cancer. 2005 May 16;5:46. | ||||||||||
| Title: | Suppression of colitis-related mouse colon carcinogenesis by a COX-2 inhibitor and PPAR ligands. | ||||||||||
| Author: | Kohno, Hiroyuki|Suzuki, Rikako|Sugie, Shigeyuki|Tanaka, Takuji | ||||||||||
| PMID: | 15892897 | ||||||||||
| 82. | |||||||||||
| Journal: | Cancer Epidemiol Biomarkers Prev. 2005 May;14(5):1224-9. | ||||||||||
| Title: | Interactions of peroxisome proliferator-activated receptor {gamma} and diet in etiology of colorectal cancer. | ||||||||||
| Author: | Murtaugh, Maureen A|Ma, Khe-Ni|Caan, Bette J|Sweeney, Carol|Wolff, Roger|Samowitz, Wade S|Potter, John D|Slattery, Martha L | ||||||||||
| PMID: | 15894676 | ||||||||||
| 83. | |||||||||||
| Journal: | Cancer Lett. 2005 Jun 16;224(1):111-6. | ||||||||||
| Title: | |||||||||||