Literatures

Primary Site >> Colorectal Cancer

Gene >> PPARD

1.
Journal:	Cell. 1999 Oct 29;99(3):335-45.
Title:	PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs.
Author:	He, T C\|Chan, T A\|Vogelstein, B\|Kinzler, K W
PMID:	10555149

2.
Journal:	Immunol Cell Biol. 2000 Aug;78(4):436-41.
Title:	Peroxisome proliferator-activated receptors in tumorigenesis: targets of tumour promotion and treatment.
Author:	Roberts-Thomson, S J
PMID:	10947870

3.
Journal:	Proc Natl Acad Sci U S A. 2000 Nov 21;97(24):13275-80.
Title:	Prostacyclin-mediated activation of peroxisome proliferator-activated receptor delta in colorectal cancer.
Author:	Gupta, R A\|Tan, J\|Krause, W F\|Geraci, M W\|Willson, T M\|Dey, S K\|DuBois, R N
PMID:	11087869

4.
Journal:	Neoplasia. 2000 Nov-Dec;2(6):483-90.
Title:	Heightened expression of cyclooxygenase-2 and peroxisome proliferator-activated receptor-delta in human endometrial adenocarcinoma.
Author:	Tong, B J\|Tan, J\|Tajeda, L\|Das, S K\|Chapman, J A\|DuBois, R N\|Dey, S K
PMID:	11228540

5.
Journal:	Int J Cancer. 2001 May 15;92(4):609-15.
Title:	Distal bowel selectivity in the chemoprevention of experimental colon carcinogenesis by the non-steroidal anti-inflammatory drug nabumetone.
Author:	Roy, H K\|Karolski, W J\|Ratashak, A
PMID:	11304699

6.
Journal:	J Cell Biol. 2001 Jul 23;154(2):369-87.
Title:	Vitamin D(3) promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of beta-catenin signaling.
Author:	Palmer, H G\|Gonzalez-Sancho, J M\|Espada, J\|Berciano, M T\|Puig, I\|Baulida, J\|Quintanilla, M\|Cano, A\|de Herreros, A G\|Lafarga, M\|Munoz, A
PMID:	11470825

7.
Journal:	Clin Colorectal Cancer. 2001 May;1(1):47-54.
Title:	The molecular basis for prevention of colorectal cancer.
Author:	Krause, W F\|DuBois, R N
PMID:	12445379

8.
Journal:	Proc Natl Acad Sci U S A. 2002 Jan 8;99(1):303-8. Epub 2001 Dec 26.
Title:	Effects of peroxisome proliferator-activated receptor delta on placentation, adiposity, and colorectal cancer.
Author:	Barak, Yaacov\|Liao, Debbie\|He, Weimin\|Ong, Estelita S\|Nelson, Michael C\|Olefsky, Jerrold M\|Boland, Richard\|Evans, Ronald M
PMID:	11756685

9.
Journal:	Cancer Res. 2003 Apr 15;63(8):1748-51.
Title:	Stromal production of prostacyclin confers an antiapoptotic effect to colonic epithelial cells.
Author:	Cutler, N Shane\|Graves-Deal, Ramona\|LaFleur, Bonnie J\|Gao, Zhenqiang\|Boman, Bruce M\|Whitehead, Robert H\|Terry, Erin\|Morrow, Jason D\|Coffey, Robert J
PMID:	12702555

10.
Journal:
Title:	3-{4-[2-[Benzoxazol-2-yl-methylamino]ethoxy]phenyl}-2-(2-[(18)F]fluoroethoxy)prop ionic acid
Author:
PMID:	20641433

11.
Journal:	Cell Cycle. 2004 Dec;3(12):1512-5. Epub 2004 Dec 6.
Title:	WNT and cyclooxygenase-2 cross-talk accelerates adenoma growth.
Author:	Wang, Dingzhi\|Mann, Jason R\|DuBois, Raymond N
PMID:	15539957

12.
Journal:	Cancer Cell. 2004 Sep;6(3):285-95.
Title:	Prostaglandin E(2) promotes colorectal adenoma growth via transactivation of the nuclear peroxisome proliferator-activated receptor delta.
Author:	Wang, Dingzhi\|Wang, Haibin\|Shi, Qiong\|Katkuri, Sharada\|Walhi, Walter\|Desvergne, Beatrice\|Das, Sanjoy K\|Dey, Sudhansu K\|DuBois, Raymond N
PMID:	15380519

13.
Journal:	Nat Med. 2004 May;10(5):481-3. Epub 2004 Mar 28.
Title:	Peroxisome proliferator-activated receptor-delta attenuates colon carcinogenesis.
Author:	Harman, Fred S\|Nicol, Christopher J\|Marin, Holly E\|Ward, Jerrold M\|Gonzalez, Frank J\|Peters, Jeffrey M
PMID:	15048110

14.
Journal:	J Biol Chem. 2004 Apr 30;279(18):18694-700. Epub 2004 Feb 19.
Title:	Polyoma enhancer activator 3, an ets transcription factor, mediates the induction of cyclooxygenase-2 by nitric oxide in colorectal cancer cells.
Author:	Liu, Yongmin\|Borchert, Gregory L\|Phang, James M
PMID:	14976201

15.
Journal:	Scand J Gastroenterol. 2005 Feb;40(2):198-205.
Title:	Peroxisome proliferator-activated receptor expression and activation in normal human colonic epithelial cells and tubular adenomas.
Author:	Matthiessen, Mads Wichmann\|Pedersen, Gitte\|Albrektsen, Tatjana\|Adamsen, Sven\|Fleckner, Jan\|Brynskov, Jorn
PMID:	15764152

16.
Journal:	Oncogene. 2006 Feb 23;25(8):1225-41.
Title:	Oxidative metabolism of linoleic acid modulates PPAR-beta/delta suppression of PPAR-gamma activity.
Author:	Zuo, X\|Wu, Y\|Morris, J S\|Stimmel, J B\|Leesnitzer, L M\|Fischer, S M\|Lippman, S M\|Shureiqi, I
PMID:	16288226

17.
Journal:	J Biol Chem. 2006 Feb 3;281(5):2676-82. Epub 2005 Nov 17.
Title:	Prostaglandin E2 regulates the nuclear receptor NR4A2 in colorectal cancer.
Author:	Holla, Vijaykumar R\|Mann, Jason R\|Shi, Qiong\|DuBois, Raymond N
PMID:	16293616

18.
Journal:	Biochem Biophys Res Commun. 2006 Feb 10;340(2):656-60.
Title:	Isoform specific changes in PPAR alpha and beta in colon and breast cancer with differentiation.
Author:	Aung, Cho S\|Faddy, Helen M\|Lister, Erin J\|Monteith, Gregory R\|Roberts-Thomson, Sarah J
PMID:	16378595

19.
Journal:	Cancer Res. 2006 Apr 15;66(8):4394-401.
Title:	Ligand activation of peroxisome proliferator-activated receptor beta inhibits colon carcinogenesis.
Author:	Marin, Holly E\|Peraza, Marjorie A\|Billin, Andrew N\|Willson, Timothy M\|Ward, Jerrold M\|Kennett, Mary J\|Gonzalez, Frank J\|Peters, Jeffrey M
PMID:	16618765

20.
Journal:	Br J Cancer. 2006 Oct 9;95(7):889-95. Epub 2006 Sep 12.
Title:	Expression of PPARdelta in multistage carcinogenesis of the colorectum: implications of malignant cancer morphology.
Author:	Takayama, O\|Yamamoto, H\|Damdinsuren, B\|Sugita, Y\|Ngan, C Y\|Xu, X\|Tsujino, T\|Takemasa, I\|Ikeda, M\|Sekimoto, M\|Matsuura, N\|Monden, M
PMID:	16969348

21.
Journal:	Ginekol Pol. 2006 Aug;77(8):643-51.
Title:	[The role of peroxisome proliferator-activated receptors (PPAR) in carcinogenesis].
Author:	Knapp, Pawel\|Jarzabek, Katarzyna\|Blachnio, Agnieszka\|Zbroch, Tomasz
PMID:	17076197

22.
Journal:	Proc Natl Acad Sci U S A. 2006 Dec 12;103(50):19069-74. Epub 2006 Dec 5.
Title:	Crosstalk between peroxisome proliferator-activated receptor delta and VEGF stimulates cancer progression.
Author:	Wang, Dingzhi\|Wang, Haibin\|Guo, Yong\|Ning, Wei\|Katkuri, Sharada\|Wahli, Walter\|Desvergne, Beatrice\|Dey, Sudhansu K\|DuBois, Raymond N
PMID:	17148604

23.
Journal:	Carcinogenesis. 2007 Jun;28(6):1202-9. Epub 2006 Dec 20.
Title:	Docosahexaenoic acid induces proteasome-dependent degradation of beta-catenin, down-regulation of survivin and apoptosis in human colorectal cancer cells not expressing COX-2.
Author:	Calviello, Gabriella\|Resci, Federica\|Serini, Simona\|Piccioni, Elisabetta\|Toesca, Amelia\|Boninsegna, Alma\|Monego, Giovanni\|Ranelletti, Franco O\|Palozza, Paola
PMID:	17183061

24.
Journal:	Cell Cycle. 2007 Mar 15;6(6):682-5.
Title:	Inflammatory mediators and nuclear receptor signaling in colorectal cancer.
Author:	Wang, Dingzhi\|DuBois, Raymond N
PMID:	17374999

25.
Journal:	J Intern Med. 2008 Jun;263(6):613-9.
Title:	A gut feeling of the PXR, PPAR and NF-kappaB connection.
Author:	Wahli, W
PMID:	18479261

26.
Journal:	Clin Sci (Lond). 2008 Aug;115(4):107-27.
Title:	Role of peroxisome-proliferator-activated receptor beta/delta (PPARbeta/delta) in gastrointestinal tract function and disease.
Author:	Peters, Jeffrey M\|Hollingshead, Holly E\|Gonzalez, Frank J
PMID:	18616431

27.
Journal:	Dis Colon Rectum. 2008 Mar;51(3):318-26; discussion 326-8.
Title:	RNA interference against peroxisome proliferator-activated receptor delta gene promotes proliferation of human colorectal cancer cells.
Author:	Yang, L\|Zhou, Z-G\|Zheng, X-L\|Wang, L\|Yu, Y-Y\|Zhou, B\|Gu, J\|Li, Y
PMID:	18214615

28.
Journal:	Carcinogenesis. 2008 Jan;29(1):169-76. Epub 2007 Sep 24.
Title:	Ligand activation of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) and inhibition of cyclooxygenase 2 (COX2) attenuate colon carcinogenesis through independent signaling mechanisms.
Author:	Hollingshead, Holly E\|Borland, Michael G\|Billin, Andrew N\|Willson, Timothy M\|Gonzalez, Frank J\|Peters, Jeffrey M
PMID:	17893232

29.
Journal:	J Invest Dermatol. 2008 Jan;128(1):110-24. Epub 2007 Jul 19.
Title:	PPARdelta enhances keratinocyte proliferation in psoriasis and induces heparin-binding EGF-like growth factor.
Author:	Romanowska, Malgorzata\|al Yacoub, Nadya\|Seidel, Henrik\|Donandt, Susanne\|Gerken, Hannah\|Phillip, Sandra\|Haritonova, Nathalie\|Artuc, Metin\|Schweiger, Susann\|Sterry, Wolfram\|Foerster, John
PMID:	17637826

30.
Journal:	Carcinogenesis. 2008 Apr;29(4):790-6.
Title:	Dietary fish oil and pectin enhance colonocyte apoptosis in part through suppression of PPARdelta/PGE2 and elevation of PGE3.
Author:	Vanamala, J\|Glagolenko, A\|Yang, P\|Carroll, R J\|Murphy, M E\|Newman, R A\|Ford, J R\|Braby, L A\|Chapkin, R S\|Turner, N D\|Lupton, J R
PMID:	18024478

31.
Journal:	Dig Dis Sci. 2009 May;54(5):1108-14.
Title:	The simultaneous expression of peroxisome proliferator-activated receptor delta and cyclooxygenase-2 may enhance angiogenesis and tumor venous invasion in tissues of colorectal cancers.
Author:	Yoshinaga, Masahiro\|Kitamura, Yosuke\|Chaen, Tomohito\|Yamashita, Shinsaku\|Tsuruta, Satoru\|Hisano, Teruaki\|Ikeda, Yoichi\|Sakai, Hironori\|Nakamura, Kazuhiko\|Takayanagi, Ryoichi\|Muto, Yoichi
PMID:	18720000

32.
Journal:	Methods Mol Biol. 2009;512:295-307.
Title:	Cyclooxygenase inhibitors induce colon cancer cell apoptosis Via PPARdelta --> 14-3-3epsilon pathway.
Author:	Wu, Kenneth K\|Liou, Jun-Yang
PMID:	19347284

33.
Journal:	Mol Carcinog. 2009 Oct;48(10):942-52.
Title:	Regulation of peroxisome proliferator-activated receptor-beta/delta by the APC/beta-CATENIN pathway and nonsteroidal antiinflammatory drugs.
Author:	Foreman, Jennifer E\|Sorg, Joseph M\|McGinnis, Kathleen S\|Rigas, Basil\|Williams, Jennie L\|Clapper, Margie L\|Gonzalez, Frank J\|Peters, Jeffrey M
PMID:	19415698

34.
Journal:	J Natl Cancer Inst. 2009 May 20;101(10):762-7.
Title:	Targeted genetic disruption of peroxisome proliferator-activated receptor-delta and colonic tumorigenesis.
Author:	Zuo, Xiangsheng\|Peng, Zhanglong\|Moussalli, Micheline J\|Morris, Jeffrey S\|Broaddus, Russell R\|Fischer, Susan M\|Shureiqi, Imad
PMID:	19436036

35.
Journal:	Mol Cancer Ther. 2009 Sep;8(9):2664-73.
Title:	Modulation of transcription by the peroxisome proliferator-activated receptor delta--binding RNA aptamer in colon cancer cells.
Author:	Kwak, Hoyun\|Hwang, Injoo\|Kim, Jee Ho\|Kim, Mee Young\|Yang, Ji Sun\|Jeong, Sunjoo
PMID:	19723884

36.
Journal:	Oncogene. 2010 Jan 28;29(4):516-26.
Title:	Knockdown of peroxisome proliferator-activated receptor-beta induces less differentiation and enhances cell-fibronectin adhesion of colon cancer cells.
Author:	Yang, L\|Olsson, B\|Pfeifer, D\|Jonsson, J-I\|Zhou, Z-G\|Jiang, X\|Fredriksson, B-A\|Zhang, H\|Sun, X-F
PMID:	19935699

37.
Journal:	Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2010 Apr;27(2):400-6.
Title:	[Construction of a lentiviral vector of RNA interference against PPARS gene and the establishment of colon cancer cell line KM12C with stable knockdown of PPARdelta expression].
Author:	Jiang, Xiao\|Yang, Lie\|Zhou, Zongguang\|Li, Yuan\|Wang, Ling\|Yu, Yongyang\|Wang, Cun
PMID:	20481327

38.
Journal:	World J Gastroenterol. 2011 Nov 14;17(42):4711-7.
Title:	miR-93 suppresses proliferation and colony formation of human colon cancer stem cells.
Author:	Yu, Xiao-Feng\|Zou, Jian\|Bao, Zhi-Jun\|Dong, Jie
PMID:	22180714

39.
Journal:	Drug Discov Today Dis Mech. 2011 Winter;8(3-4):e85-e93.
Title:	Modulation of gastrointestinal inflammation and colorectal tumorigenesis by peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta).
Author:	Peters, Jeffrey M\|Morales, Jose L\|Gonzalez, Frank J
PMID:	22611424

40.
Journal:	Clin Cancer Res. 2011 Jun 1;17(11):3760-70.
Title:	Biological function and prognostic significance of peroxisome proliferator-activated receptor delta in rectal cancer.
Author:	Yang, Lie\|Zhang, Hong\|Zhou, Zong-Guang\|Yan, Hui\|Adell, G\|Sun, Xiao-Feng
PMID:	21531809

41.
Journal:	Mol Carcinog. 2011 Nov;50(11):884-900.
Title:	Functional characterization of peroxisome proliferator-activated receptor-beta/delta expression in colon cancer.
Author:	Foreman, Jennifer E\|Chang, Wen-Chi L\|Palkar, Prajakta S\|Zhu, Bokai\|Borland, Michael G\|Williams, Jennie L\|Kramer, Lance R\|Clapper, Margie L\|Gonzalez, Frank J\|Peters, Jeffrey M
PMID:	21400612

42.
Journal:	Dig Dis Sci. 2011 Apr;56(4):1194-200.
Title:	The expression of both peroxisome proliferator-activated receptor delta and cyclooxygenase-2 in tissues is associated with poor prognosis in colorectal cancer patients.
Author:	Yoshinaga, Masahiro\|Taki, Kentaro\|Somada, Shinichi\|Sakiyama, Yumiko\|Kubo, Norihiko\|Kaku, Toyoma\|Tsuruta, Satoru\|Kusumoto, Tetsuya\|Sakai, Hironori\|Nakamura, Kazuhiko\|Takayanagi, Ryoichi\|Muto, Yoichi
PMID:	20824502

43.
Journal:	J Cancer Res Clin Oncol. 2011 Jan;137(1):29-39.
Title:	Peroxisome-proliferator-activated receptors gamma and beta/delta mediate vascular endothelial growth factor production in colorectal tumor cells.
Author:	Rohrl, Clemens\|Kaindl, Ulrike\|Koneczny, Inga\|Hudec, Xenia\|Baron, David M\|Konig, Jurgen S\|Marian, Brigitte
PMID:	20221637

44.
Journal:	PPAR Res. 2012;2012:876418.
Title:	The role of peroxisome proliferator-activated receptors in colorectal cancer.
Author:	Park, Joo-In\|Kwak, Jong-Young
PMID:	23024650

45.
Journal:	J Biol Chem. 2012 Nov 30;287(49):41364-73.
Title:	beta-Catenin and peroxisome proliferator-activated receptor-delta coordinate dynamic chromatin loops for the transcription of vascular endothelial growth factor A gene in colon cancer cells.
Author:	Hwang, Injoo\|Kim, Jeeho\|Jeong, Sunjoo
PMID:	23086933

46.
Journal:	Biochem Pharmacol. 2013 Mar 1;85(5):607-11.
Title:	Targeting peroxisome proliferator-activated receptor-beta/delta in colon cancer: how to aim?
Author:	Xu, Min\|Zuo, Xiangsheng\|Shureiqi, Imad
PMID:	23041232

47.
Journal:	Tumour Biol. 2013 Dec;34(6):3619-25.
Title:	Transcription factor AP1 binds the functional region of the promoter and regulates gene expression of human PPARdelta in LoVo cell.
Author:	Jiang, Xiaogang\|Yang, Xudong\|Han, Yan\|Lu, Shemin
PMID:	23832539

48.
Journal:	PLoS One. 2013 Dec 31;8(12):e83952.
Title:	Variants of the PPARD gene and their clinicopathological significance in colorectal cancer.
Author:	Ticha, Ivana\|Gnosa, Sebastian\|Lindblom, Annika\|Liu, Tao\|Sun, Xiao-Feng
PMID:	24391853

49.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2014 Jan;17(1):26-30.
Title:	[Detection of fecal peroxisome proliferator-activated receptor delta and cyclooxygenase 2 mRNA in screening of colorectal cancer].
Author:	Yu, Huangdao\|Yang, Lie\|Yan, Fangfang\|Li, Yuan\|Sun, Xiaofeng\|Zhou, Zongguang
PMID:	24519045

50.
Journal:	J Natl Cancer Inst. 2014 Apr;106(4):dju052.
Title:	Potentiation of colon cancer susceptibility in mice by colonic epithelial PPAR-delta/beta overexpression.
Author:	Zuo, Xiangsheng\|Xu, Min\|Yu, Jiang\|Wu, Yuanqing\|Moussalli, Micheline J\|Manyam, Ganiraju C\|Lee, Sun Il\|Liang, Shoudan\|Gagea, Mihai\|Morris, Jeffrey S\|Broaddus, Russell R\|Shureiqi, Imad
PMID:	24681603

51.
Journal:	FASEB J. 2015 Jun;29(6):2359-70.
Title:	15-Lipoxygenase-1 suppression of colitis-associated colon cancer through inhibition of the IL-6/STAT3 signaling pathway.
Author:	Mao, Fei\|Xu, Min\|Zuo, Xiangsheng\|Yu, Jiang\|Xu, Weiguo\|Moussalli, Micheline J\|Elias, Elias\|Li, Haiyan S\|Watowich, Stephanie S\|Shureiqi, Imad
PMID:	25713055

52.
Journal:	Clin Cancer Res. 2016 Dec 1;22(23):5636-5641.
Title:	Molecular Pathways: Dietary Regulation of Stemness and Tumor Initiation by the PPAR-delta Pathway.
Author:	Beyaz, Semir\|Yilmaz, Omer H
PMID:	27702819

53.
Journal:	JCI Insight. 2017 Jan 12;2(1):e91419.
Title:	Metastasis regulation by PPARD expression in cancer cells.
Author:	Zuo, Xiangsheng\|Xu, Weiguo\|Xu, Min\|Tian, Rui\|Moussalli, Micheline J\|Mao, Fei\|Zheng, Xiaofeng\|Wang, Jing\|Morris, Jeffrey S\|Gagea, Mihai\|Eng, Cathy\|Kopetz, Scott\|Maru, Dipen M\|Rashid, Asif\|Broaddus, Russell\|Wei, Daoyan\|Hung, Mien-Chie\|Sood, Anil K\|Shureiqi,
PMID:	28097239

54.
Journal:	Genet Mol Res. 2017 Jan 23;16(1). pii: gmr-16-01-gmr.16019324.
Title:	Protective role of +294 T/C (rs2016520) polymorphism of PPARD in Mexican patients with colorectal cancer.
Author:	Rosales-Reynoso, M A\|Wence-Chavez, L I\|Arredondo-Valdez, A R\|Dumois-Petersen, S\|Barros-Nunez, P\|Gallegos-Arreola, M P\|Flores-Martinez, S E\|Sanchez-Corona, J
PMID:	28128413

55.
Journal:	Oncogene. 2018 Apr;37(15):2067-2078.
Title:	ROS release by PPARbeta/delta-null fibroblasts reduces tumor load through epithelial antioxidant response.
Author:	Tan, Eddie Han Pin\|Sng, Ming Keat\|How, Ivan Shun Bo\|Chan, Jeremy Soon Kiat\|Chen, Jiapeng\|Tan, Chek Kun\|Wahli, Walter\|Tan, Nguan Soon
PMID:	29367760

56.
Journal:	Int J Mol Med. 2018 Aug;42(2):713-725.
Title:	Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review).
Author:	Katoh, Masaru
PMID:	29786110