Primary Site >> Colorectal Cancer

Gene >> PPARA

1.
Journal: Z Gastroenterol. 1999 Mar;37(3):257-61.
Title: [Nonsteroidal anti-rheumatic drugs and colon carcinoma: COX versus PPAR].
Author: Wachtershauser, A|Stein, J
PMID: 10234800
2.
Journal: Carcinogenesis. 1999 Jun;20(6):985-9.
Title: Impairment of peroxisomal biogenesis in human colon carcinoma.
Author: Lauer, C|Volkl, A|Riedl, S|Fahimi, H D|Beier, K
PMID: 10357777
3.
Journal: Biochem Biophys Res Commun. 2000 Jun 7;272(2):380-5.
Title: PPAR-gamma is selectively upregulated in Caco-2 cells by butyrate.
Author: Wachtershauser, A|Loitsch, S M|Stein, J
PMID: 10833422
4.
Journal: Immunol Cell Biol. 2000 Aug;78(4):436-41.
Title: Peroxisome proliferator-activated receptors in tumorigenesis: targets of tumour promotion and treatment.
Author: Roberts-Thomson, S J
PMID: 10947870
5.
Journal: Br J Cancer. 2000 Nov;83(10):1394-400.
Title: Expression of peroxisome proliferator-activated receptor (PPAR)gamma in gastric cancer and inhibitory effects of PPARgamma agonists.
Author: Sato, H|Ishihara, S|Kawashima, K|Moriyama, N|Suetsugu, H|Kazumori, H|Okuyama, T|Rumi, M A|Fukuda, R|Nagasue, N|Kinoshita, Y
PMID: 11044367
6.
Journal: Cancer Res. 2001 Mar 15;61(6):2424-8.
Title: Ligands for peroxisome proliferator-activated receptors alpha and gamma inhibit chemically induced colitis and formation of aberrant crypt foci in rats.
Author: Tanaka, T|Kohno, H|Yoshitani, S|Takashima, S|Okumura, A|Murakami, A|Hosokawa, M
PMID: 11289109
7.
Journal: J Biol Chem. 2001 Aug 10;276(32):29681-7.
Title: Target genes of peroxisome proliferator-activated receptor gamma in colorectal cancer cells.
Author: Gupta, R A|Brockman, J A|Sarraf, P|Willson, T M|DuBois, R N
PMID: 11397807
8.
Journal: Exp Cell Res. 2001 Jul 1;267(1):73-80.
Title: Effect of PPAR activators on cytokine-stimulated cyclooxygenase-2 expression in human colorectal carcinoma cells.
Author: Ikawa, H|Kameda, H|Kamitani, H|Baek, S J|Nixon, J B|Hsi, L C|Eling, T E
PMID: 11412039
9.
Journal: Carcinogenesis. 2001 Sep;22(9):1379-83.
Title: Activation of the PPAR pathway induces apoptosis and COX-2 inhibition in HT-29 human colon cancer cells.
Author: Yang, W L|Frucht, H
PMID: 11532858
10.
Journal: Int J Oncol. 2001 Dec;19(6):1255-62.
Title: Docosahexaenoic acid regulated genes and transcription factors inducing apoptosis in human colon cancer cells.
Author: Narayanan, B A|Narayanan, N K|Reddy, B S
PMID: 11713597
11.
Journal: J Cell Physiol. 2002 Mar;190(3):279-86.
Title: Many actions of cyclooxygenase-2 in cellular dynamics and in cancer.
Author: Cao, Yang|Prescott, Stephen M
PMID: 11857443
12.
Journal: Gut. 2002 May;50(5):658-64.
Title: Characteristics of the peroxisome proliferator activated receptor gamma (PPARgamma) ligand induced apoptosis in colon cancer cells.
Author: Shimada, T|Kojima, K|Yoshiura, K|Hiraishi, H|Terano, A
PMID: 11950812
13.
Journal: Aliment Pharmacol Ther. 2002 Apr;16 Suppl 2:102-6.
Title: Review article: COX-2, prostanoids and colon cancer.
Author: Ota, S|Bamba, H|Kato, A|Kawamoto, C|Yoshida, Y|Fujiwara, K
PMID: 11966530
14.
Journal: Biol Cell. 2002 Feb;94(1):15-27.
Title: Expression of peroxisome proliferator-activated receptors alpha and gamma in differentiating human colon carcinoma Caco-2 cells.
Author: Huin, Cecile|Schohn, Herve|Hatier, Renee|Bentejac, Marc|Antunes, Laurent|Plenat, Francois|Bugaut, Maurice|Dauca, Michel
PMID: 12000143
15.
Journal: Biochem Biophys Res Commun. 2002 Nov 15;298(5):667-74.
Title: Docosahexaenoic acid suppresses the activity of peroxisome proliferator-activated receptors in a colon tumor cell line.
Author: Lee, Joo Y|Hwang, Daniel H
PMID: 12419306
16.
Journal: Mol Cancer Ther. 2002 Mar;1(5):357-63.
Title: Peroxisome proliferator-activated receptor modulators as potential chemopreventive agents.
Author: Kopelovich, Levy|Fay, Judith R|Glazer, Robert I|Crowell, James A
PMID: 12489852
17.
Journal: J Pharmacol Exp Ther. 2003 May;305(2):632-7.
Title: Activation of peroxisome proliferator-activated receptor gamma does not explain the antiproliferative activity of the nonsteroidal anti-inflammatory drug indomethacin on human colorectal cancer cells.
Author: Hawcroft, G|Gardner, S H|Hull, M A
PMID: 12606626
18.
Journal: Comp Hepatol. 2003 Jan 31;2(1):3.
Title: Advances in understanding the regulation of apoptosis and mitosis by peroxisome-proliferator activated receptors in pre-clinical models: relevance for human health and disease.
Author: Boitier, Eric|Gautier, Jean-Charles|Roberts, Ruth
PMID: 12622871
19.
Journal: Biochem Soc Trans. 2003 Apr;31(2):388-92.
Title: Polyamines as modifiers of genetic risk factors in human intestinal cancers.
Author: Babbar, N|Gerner, E W
PMID: 12653645
20.
Journal: Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9968-73. Epub 2003 Aug 8.
Title: The 15-lipoxygenase-1 product 13-S-hydroxyoctadecadienoic acid down-regulates PPAR-delta to induce apoptosis in colorectal cancer cells.
Author: Shureiqi, Imad|Jiang, Wei|Zuo, Xiangsheng|Wu, Yuanqing|Stimmel, Julie B|Leesnitzer, Lisa M|Morris, Jeffrey S|Fan, Hui-Zhen|Fischer, Susan M|Lippman, Scott M
PMID: 12909723
21.
Journal: Gut. 2003 Sep;52(9):1317-22.
Title: Potential role for peroxisome proliferator activated receptor (PPAR) in preventing colon cancer.
Author: Jackson, L|Wahli, W|Michalik, L|Watson, S A|Morris, T|Anderton, K|Bell, D R|Smith, J A|Hawkey, C J|Bennett, A J
PMID: 12912864
22.
Journal: Arch Pathol Lab Med. 2003 Sep;127(9):1121-3.
Title: The role of peroxisome proliferator-activated receptor gamma in colon cancer and inflammatory bowel disease.
Author: Bull, Arthur W
PMID: 12946234
23.
Journal: Carcinogenesis. 2003 Nov;24(11):1717-22.
Title: Activation of PPAR gamma in colon tumor cell lines by oxidized metabolites of linoleic acid, endogenous ligands for PPAR gamma.
Author: Bull, Arthur W|Steffensen, Knut R|Leers, Jorg|Rafter, Joseph J
PMID: 12949056
24.
Journal: J Biol Chem. 2003 Nov 28;278(48):47762-75.
Title: Cyclooxygenase-independent induction of apoptosis by sulindac sulfone is mediated by polyamines in colon cancer.
Author: Babbar, Naveen|Ignatenko, Natalia A|Casero, Robert A Jr|Gerner, Eugene W
PMID: 14506281
25.
Journal: BMC Cancer. 2003 Oct 1;3:25.
Title: Gamma (gamma) tocopherol upregulates peroxisome proliferator activated receptor (PPAR) gamma (gamma) expression in SW 480 human colon cancer cell lines.
Author: Campbell, Sharon E|Stone, William L|Whaley, Sarah G|Qui, Min|Krishnan, Koyamangalath
PMID: 14521714
26.
Journal: Cancer Res. 2003 Sep 15;63(18):6090-5.
Title: Concomitant suppression of hyperlipidemia and intestinal polyp formation in Apc-deficient mice by peroxisome proliferator-activated receptor ligands.
Author: Niho, Naoko|Takahashi, Mami|Kitamura, Tomohiro|Shoji, Yutaka|Itoh, Masaki|Noda, Tetsuo|Sugimura, Takashi|Wakabayashi, Keiji
PMID: 14522940
27.
Journal: Z Gastroenterol. 2003 Oct;41(10):1035-8.
Title: [PPAR-ligands: a clinically important regulatory system with multiple options in the treatment of diabetes mellitus, inflammatory bowel disease and in the chemoprevention of colon cancer?].
Author: Allgayer, H|Kruis, W
PMID: 14562202
28.
Journal: Endocr Regul. 2003 Sep;37(3):137-44.
Title: Hyperlipidic diets induce early alterations of the vitamin A signalling pathway in rat colonic mucosa.
Author: Groubet, R|Pallet, V|Delage, B|Redonnet, A|Higueret, P|Cassand, P
PMID: 14986719
29.
Journal: J Endocrinol Invest. 2003 Nov;26(11):1054-8.
Title: Colonic polyps of acromegalic patients are not associated with mutations of the peroxisome proliferator activated receptor gamma gene.
Author: Bogazzi, F|Ultimieri, F|Raggi, F|Russo, D|Brogioni, S|Cosci, C|Gasperi, M|Costa, A|Viacava, P|Mosca, F|Bartalena, L|Martino, E
PMID: 15008240
30.
Journal: J Cancer Res Clin Oncol. 2004 Feb;130(2):73-9. Epub 2003 Nov 21.
Title: Induction of differentiation and peroxisome proliferator-activated receptor gamma expression in colon cancer cell lines by troglitazone.
Author: Kato, Masashi|Kusumi, Tomomi|Tsuchida, Shigeki|Tanaka, Masanori|Sasaki, Mutsuo|Kudo, Hajime
PMID: 14634802
31.
Journal: Cancer Lett. 2004 Jan 8;203(1):25-33.
Title: Peroxisome proliferator-activated receptors (PPARs) and associated transcription factors in colon cancer: reduced expression of PPARgamma-coactivator 1 (PGC-1).
Author: Feilchenfeldt, Jonas|Brundler, Marie Anne|Soravia, Claudio|Totsch, Martin|Meier, Christoph A
PMID: 14670614
32.
Journal: Regul Pept. 2004 Aug 15;120(1-3):243-51.
Title: PPARalpha agonists stimulate progastrin production in human colorectal carcinoma cells.
Author: Lachal, Shamilah|Ford, Joanne|Shulkes, Arthur|Baldwin, Graham S
PMID: 15177943
33.
Journal: Cancer Sci. 2004 Jun;95(6):481-6.
Title: Pomegranate seed oil rich in conjugated linolenic acid suppresses chemically induced colon carcinogenesis in rats.
Author: Kohno, Hiroyuki|Suzuki, Rikako|Yasui, Yumiko|Hosokawa, Masashi|Miyashita, Kazuo|Tanaka, Takuji
PMID: 15182427
34.
Journal: Biochim Biophys Acta. 2004 Nov 18;1675(1-3):113-9.
Title: Fucoxanthin induces apoptosis and enhances the antiproliferative effect of the PPARgamma ligand, troglitazone, on colon cancer cells.
Author: Hosokawa, Masashi|Kudo, Masahiro|Maeda, Hayato|Kohno, Hiroyuki|Tanaka, Takuji|Miyashita, Kazuo
PMID: 15535974
35.
Journal:
Title: 3-{4-[2-[Benzoxazol-2-yl-methylamino]ethoxy]phenyl}-2-(2-[(18)F]fluoroethoxy)prop ionic acid
Author:
PMID: 20641433
36.
Journal: Int J Biochem Cell Biol. 2005 Mar;37(3):645-54.
Title: Ciglitazone induces early cellular proliferation and NF-kappaB transcriptional activity in colon cancer cells through p65 phosphorylation.
Author: Chen, Fei|Harrison, Lawrence E
PMID: 15618021
37.
Journal: Proc Natl Acad Sci U S A. 2005 Feb 22;102(8):2970-4.
Title: Concurrent suppression of hyperlipidemia and intestinal polyp formation by NO-1886, increasing lipoprotein lipase activity in Min mice.
Author: Niho, Naoko|Mutoh, Michihiro|Takahashi, Mami|Tsutsumi, Kazuhiko|Sugimura, Takashi|Wakabayashi, Keiji
PMID: 15710887
38.
Journal: Scand J Gastroenterol. 2005 Feb;40(2):198-205.
Title: Peroxisome proliferator-activated receptor expression and activation in normal human colonic epithelial cells and tubular adenomas.
Author: Matthiessen, Mads Wichmann|Pedersen, Gitte|Albrektsen, Tatjana|Adamsen, Sven|Fleckner, Jan|Brynskov, Jorn
PMID: 15764152
39.
Journal: Mol Cell Endocrinol. 2005 May 12;235(1-2):21-9. Epub 2005 Mar 16.
Title: Selective activation of PPARgamma in breast, colon, and lung cancer cell lines.
Author: Allred, Clinton D|Kilgore, Michael W
PMID: 15866424
40.
Journal: BMC Cancer. 2005 May 16;5:46.
Title: Suppression of colitis-related mouse colon carcinogenesis by a COX-2 inhibitor and PPAR ligands.
Author: Kohno, Hiroyuki|Suzuki, Rikako|Sugie, Shigeyuki|Tanaka, Takuji
PMID: 15892897
41.
Journal: Mol Pharmacol. 2005 Nov;68(5):1203-13. Epub 2005 Aug 2.
Title: 15-deoxy-Delta12,14 prostaglandin J2 up-regulates Kruppel-like factor 4 expression independently of peroxisome proliferator-activated receptor gamma by activating the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase signal tra
Author: Chen, Zhi Yi|Tseng, Chi-Chuan
PMID: 16077033
42.
Journal: Endocr Rev. 2005 Dec;26(7):898-915. Epub 2005 Aug 26.
Title: Interaction of nuclear receptors with the Wnt/beta-catenin/Tcf signaling axis: Wnt you like to know?
Author: Mulholland, David J|Dedhar, Shoukat|Coetzee, Gerhard A|Nelson, Colleen C
PMID: 16126938
43.
Journal: Int J Cancer. 2006 Feb 1;118(3):571-6.
Title: Conjugated linoleic acid inhibits peritoneal metastasis in human gastrointestinal cancer cells.
Author: Kuniyasu, Hiroki|Yoshida, Kazuhiro|Sasaki, Takamitsu|Sasahira, Tomonori|Fujii, Kiyomu|Ohmori, Hitoshi
PMID: 16106401
44.
Journal: Oncogene. 2006 Feb 23;25(8):1225-41.
Title: Oxidative metabolism of linoleic acid modulates PPAR-beta/delta suppression of PPAR-gamma activity.
Author: Zuo, X|Wu, Y|Morris, J S|Stimmel, J B|Leesnitzer, L M|Fischer, S M|Lippman, S M|Shureiqi, I
PMID: 16288226
45.
Journal: J Biol Chem. 2006 Jan 27;281(4):2044-52.
Title: Proline oxidase, a proapoptotic gene, is induced by troglitazone: evidence for both peroxisome proliferator-activated receptor gamma-dependent and -independent mechanisms.
Author: Pandhare, Jui|Cooper, Sandra K|Phang, James M
PMID: 16303758
46.
Journal: Biochem J. 2006 Apr 1;395(1):81-8.
Title: Peroxisome-proliferator-activated receptor alpha agonists inhibit cyclo-oxygenase 2 and vascular endothelial growth factor transcriptional activation in human colorectal carcinoma cells via inhibition of activator protein-1.
Author: Grau, Raquel|Punzon, Carmen|Fresno, Manuel|Iniguez, Miguel A
PMID: 16343055
47.
Journal: Biochem Biophys Res Commun. 2006 Feb 10;340(2):656-60.
Title: Isoform specific changes in PPAR alpha and beta in colon and breast cancer with differentiation.
Author: Aung, Cho S|Faddy, Helen M|Lister, Erin J|Monteith, Gregory R|Roberts-Thomson, Sarah J
PMID: 16378595
48.
Journal: Carcinogenesis. 2006 Sep;27(9):1797-802.
Title: Peroxisome proliferator-activated receptor (PPAR) gamma gene polymorphisms and colorectal cancer risk among Chinese in Singapore.
Author: Koh, Woon-Puay|Yuan, Jian-Min|Van Den Berg, David|Ingles, Sue A|Yu, Mimi C
PMID: 16513680
49.
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2006 Mar;9(2):157-60.
Title: [Refined deletion mapping of loss of heterozygosity on 22q13 in sporadic colorectal carcinoma].
Author: Zheng, Hai-tao|Tang, Hua-mei|Peng, Zhi-hai|Zhou, Chong-zhi|He, Lin
PMID: 16555160
50.
Journal: Biol Chem. 2006 Apr;387(4):381-5.
Title: Concomitant suppression of hyperlipidemia and intestinal polyp formation by increasing lipoprotein lipase activity in Apc-deficient mice.
Author: Mutoh, Michihiro|Niho, Naoko|Wakabayashi, Keiji
PMID: 16606335
51.
Journal: Ginekol Pol. 2006 Aug;77(8):643-51.
Title: [The role of peroxisome proliferator-activated receptors (PPAR) in carcinogenesis].
Author: Knapp, Pawel|Jarzabek, Katarzyna|Blachnio, Agnieszka|Zbroch, Tomasz
PMID: 17076197
52.
Journal: PPAR Res. 2007;2007:93416.
Title: Involvement of PPARs in Cell Proliferation and Apoptosis in Human Colon Cancer Specimens and in Normal and Cancer Cell Lines.
Author: Martinasso, G|Oraldi, M|Trombetta, A|Maggiora, M|Bertetto, O|Canuto, R A|Muzio, G
PMID: 17389773
53.
Journal: Int J Oncol. 2007 May;30(5):1215-22.
Title: Thiazolidinedione drugs down-regulate CXCR4 expression on human colorectal cancer cells in a peroxisome proliferator activated receptor gamma-dependent manner.
Author: Richard, Cynthia Lee|Blay, Jonathan
PMID: 17390024
54.
Journal: J Clin Oncol. 2007 Apr 20;25(12):1476-81.
Title: Thiazolidinediones and the risk of lung, prostate, and colon cancer in patients with diabetes.
Author: Govindarajan, Rangaswamy|Ratnasinghe, Luke|Simmons, Debra L|Siegel, Eric R|Midathada, Madhu V|Kim, Lawrence|Kim, Peter J|Owens, Randall J|Lang, Nicholas P
PMID: 17442990
55.
Journal: Gastroenterology. 2007 Jul;133(1):108-23.
Title: Fenofibrate represses interleukin-17 and interferon-gamma expression and improves colitis in interleukin-10-deficient mice.
Author: Lee, Jimmy W|Bajwa, Poonam J|Carson, Monica J|Jeske, Daniel R|Cong, Yingzi|Elson, Charles O|Lytle, Christian|Straus, Daniel S
PMID: 17631136
56.
Journal: Chem Biol Interact. 2007 Aug 30;169(2):110-21. Epub 2007 Jun 14.
Title: Antiproliferative effect of conjugated linoleic acid in caco-2 cells: involvement of PPARgamma and APC/beta-catenin pathways.
Author: Bozzo, Francesca|Bocca, Claudia|Colombatto, Sebastiano|Miglietta, Antonella
PMID: 17632092
57.
Journal: Histopathology. 2007 Oct;51(4):520-7. Epub 2007 Aug 17.
Title: Reversal of expression of 15-lipoxygenase-1 to cyclooxygenase-2 is associated with development of colonic cancer.
Author: Yuri, M|Sasahira, T|Nakai, K|Ishimaru, S|Ohmori, H|Kuniyasu, H
PMID: 17711445
58.
Journal: Nucleic Acids Symp Ser (Oxf). 2007;(51):441-2.
Title: Antisense activity of 2',4'-BNA targeted to PPAR gamma in THP-1 and HCT116 cells.
Author: Tachibana, Keisuke|Katayama, Tatsuya|Ueda, Chihiro|Sumitomo, Mikako|Tagami, Masayuki|Ishimoto, Kenji|Yamasaki, Daisuke|Tanaka, Toshiya|Hamakubo, Takao|Sakai, Juro|Kodama, Tatsuhiko|Obika, Satoshi|Imanishi, Takeshi|Doi, Takefumi
PMID: 18029776
59.
Journal: Dig Dis Sci. 2008 Mar;53(3):614-21.
Title: Influence of peroxisome proliferator-activated receptor (PPAR)gamma Plo12Ala polymorphism as a shared risk marker for both gastric cancer and impaired fasting glucose (IFG) in Japanese.
Author: Tahara, Tomomitsu|Arisawa, Tomiyasu|Shibata, Tomoyuki|Nakamura, Masakatsu|Wang, Fangyu|Maruyama, Naoko|Kamiya, Yoshio|Nakamura, Masahiko|Fujita, Hiroshi|Nagasaka, Mitsuo|Iwata, Masami|Takahama, Kazuya|Watanabe, Makoto|Hirata, Ichiro|Nakano, Hiroshi
PMID: 17763950
60.
Journal: Proteomics. 2008 Jan;8(1):45-61.
Title: Transcriptome and proteome profiling of colon mucosa from quercetin fed F344 rats point to tumor preventive mechanisms, increased mitochondrial fatty acid degradation and decreased glycolysis.
Author: Dihal, Ashwin A|van der Woude, Hester|Hendriksen, Peter J M|Charif, Halima|Dekker, Lennard J|Ijsselstijn, Linda|de Boer, Vincent C J|Alink, Gerrit M|Burgers, Peter C|Rietjens, Ivonne M C M|Woutersen, Ruud A|Stierum, Rob H
PMID: 18095365
61.
Journal: J Nutr. 2008 Feb;138(2):250-6.
Title: PPARgamma1 as a molecular target of eicosapentaenoic acid in human colon cancer (HT-29) cells.
Author: Allred, Clinton D|Talbert, Dominique R|Southard, R Chase|Wang, Xin|Kilgore, Michael W
PMID: 18203887
62.
Journal: J Intern Med. 2008 Jun;263(6):613-9.
Title: A gut feeling of the PXR, PPAR and NF-kappaB connection.
Author: Wahli, W
PMID: 18479261
63.
Journal: PPAR Res. 2008;2008:785405.
Title: PPARgamma Inhibitors as Novel Tubulin-Targeting Agents.
Author: Schaefer, Katherine L
PMID: 18509498
64.
Journal: PPAR Res. 2008;2008:181047.
Title: Synergistic Effects of PPARgamma Ligands and Retinoids in Cancer Treatment.
Author: Shimizu, Masahito|Moriwaki, Hisataka
PMID: 18528526
65.
Journal: Cardiovasc Diabetol. 2008 Jun 19;7:18.
Title: Does the lipid-lowering peroxisome proliferator-activated receptors ligand bezafibrate prevent colon cancer in patients with coronary artery disease?
Author: Tenenbaum, Alexander|Boyko, Valentina|Fisman, Enrique Z|Goldenberg, Ilan|Adler, Yehuda|Feinberg, Micha S|Motro, Michael|Tanne, David|Shemesh, Joseph|Schwammenthal, Ehud|Behar, Solomon
PMID: 18565233
66.
Journal: J Gastroenterol. 2008;43(7):538-49.
Title: Peroxisome proliferator-activated receptor alpha activates cyclooxygenase-2 gene transcription through bile acid transport in human colorectal cancer cell lines.
Author: Oshio, Hiroshi|Abe, Takaaki|Onogawa, Tohru|Ohtsuka, Hideo|Sato, Takeaki|Ii, Takayuki|Fukase, Kouji|Muto, Mitsuhisa|Katayose, Yu|Oikawa, Masaya|Rikiyama, Toshiki|Egawa, Shinichi|Unno, Michiaki
PMID: 18648741
67.
Journal: J Nutr Sci Vitaminol (Tokyo). 2008 Aug;54(4):298-302.
Title: PPAR alpha and PPAR delta transactivity and p300 binding activity induced by arachidonic acid in colorectal cancer cell line Caco-2.
Author: Mochizuki, Kazuki|Suzuki, Takuji|Goda, Toshinao
PMID: 18797151
68.
Journal: Onco Targets Ther. 2008 Oct 1;1:41-8.
Title: Relationship between arachidonic acid pathway and human renal cell carcinoma.
Author: Matsuyama, Masahide|Yoshimura, Rikio
PMID: 21127751
69.
Journal: J Invest Surg. 2009 Mar-Apr;22(2):105-11.
Title: Influence of tumor peroxisome proliferator-activated receptor gamma and delta expression on postoperative mortality of patients undergoing colorectal cancer surgery.
Author: Ishizuka, Mitsuru|Sawada, Tokihiko|Okada, Toshie|Nagata, Hitoshi|Takagi, Kazutoshi|Horie, Toru|Kubota, Keiichi
PMID: 19283612
70.
Journal: Methods Mol Biol. 2009;512:295-307.
Title: Cyclooxygenase inhibitors induce colon cancer cell apoptosis Via PPARdelta --> 14-3-3epsilon pathway.
Author: Wu, Kenneth K|Liou, Jun-Yang
PMID: 19347284
71.
Journal: Mol Carcinog. 2009 Oct;48(10):942-52.
Title: Regulation of peroxisome proliferator-activated receptor-beta/delta by the APC/beta-CATENIN pathway and nonsteroidal antiinflammatory drugs.
Author: Foreman, Jennifer E|Sorg, Joseph M|McGinnis, Kathleen S|Rigas, Basil|Williams, Jennie L|Clapper, Margie L|Gonzalez, Frank J|Peters, Jeffrey M
PMID: 19415698
72.
Journal: Int J Cancer. 2009 Dec 15;125(12):2802-9.
Title: KLF4-dependent, PPARgamma-induced expression of GPA33 in colon cancer cell lines.
Author: Rageul, Julie|Mottier, Stephanie|Jarry, Anne|Shah, Yatrik|Theoleyre, Sandrine|Masson, Damien|Gonzalez, Frank J|Laboisse, Christian L|Denis, Marc G
PMID: 19551868
73.
Journal: Mol Cancer Ther. 2009 Sep;8(9):2664-73.
Title: Modulation of transcription by the peroxisome proliferator-activated receptor delta--binding RNA aptamer in colon cancer cells.
Author: Kwak, Hoyun|Hwang, Injoo|Kim, Jee Ho|Kim, Mee Young|Yang, Ji Sun|Jeong, Sunjoo
PMID: 19723884
74.
Journal: Tumour Biol. 2009;30(4):185-99.
Title: 15-lipoxygenase-1 in colorectal cancer: a review.
Author: Bhattacharya, S|Mathew, G|Jayne, D G|Pelengaris, S|Khan, M
PMID: 19752603
75.
Journal: J Oncol. 2009;2009:867915.
Title: Decreased polyunsaturated Fatty Acid content contributes to increased survival in human colon cancer.
Author: Oraldi, Manuela|Trombetta, Antonella|Biasi, Fiorella|Canuto, Rosa A|Maggiora, Marina|Muzio, Giuliana
PMID: 19841681
76.
Journal: Cancer Lett. 2010 Nov 1;297(1):65-74.
Title: RXRgamma and PPARgamma ligands in combination to inhibit proliferation and invasiveness in colon cancer cells.
Author: Papi, Alessio|Rocchi, Paola|Ferreri, Anna Maria|Orlandi, Marina
PMID: 20510503
77.
Journal: Chem Biol Interact. 2010 Oct 6;188(1):75-85.
Title: Suppression of NF-kappaB and GSK-3beta is involved in colon cancer cell growth inhibition by the PPAR agonist troglitazone.
Author: Ban, Jung Ok|Kwak, Dong Hoon|Oh, Ju Hoon|Park, Eun-Jung|Cho, Min-Chul|Song, Ho Seub|Song, Min Jong|Han, Sang Bae|Moon, Dong Cheul|Kang, Keon Wook|Hong, Jin Tae
PMID: 20540935
78.
Journal: J Cancer Res Clin Oncol. 2011 Jan;137(1):29-39.
Title: Peroxisome-proliferator-activated receptors gamma and beta/delta mediate vascular endothelial growth factor production in colorectal tumor cells.
Author: Rohrl, Clemens|Kaindl, Ulrike|Koneczny, Inga|Hudec, Xenia|Baron, David M|Konig, Jurgen S|Marian, Brigitte
PMID: 20221637
79.
Journal: Dig Dis Sci. 2011 Apr;56(4):1194-200.
Title: The expression of both peroxisome proliferator-activated receptor delta and cyclooxygenase-2 in tissues is associated with poor prognosis in colorectal cancer patients.
Author: Yoshinaga, Masahiro|Taki, Kentaro|Somada, Shinichi|Sakiyama, Yumiko|Kubo, Norihiko|Kaku, Toyoma|Tsuruta, Satoru|Kusumoto, Tetsuya|Sakai, Hironori|Nakamura, Kazuhiko|Takayanagi, Ryoichi|Muto, Yoichi
PMID: 20824502
80.
Journal: Cancer Sci. 2011 May;102(5):999-1006.
Title: Adiponectin supports cell survival in glucose deprivation through enhancement of autophagic response in colorectal cancer cells.
Author: Habeeb, Baker S|Kitayama, Joji|Nagawa, Hirokazu
PMID: 21299716
81.
Journal: Clin Cancer Res. 2011 Jun 1;17(11):3760-70.
Title: Biological function and prognostic significance of peroxisome proliferator-activated receptor delta in rectal cancer.
Author: Yang, Lie|Zhang, Hong|Zhou, Zong-Guang|Yan, Hui|Adell, G|Sun, Xiao-Feng
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Journal: Mol Cell Biochem. 2011 Nov;357(1-2):235-45.
Title: Simulated colon fiber metabolome regulates genes involved in cell cycle, apoptosis, and energy metabolism in human colon cancer cells.
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Journal: Int J Oncol. 2011 Nov;39(5):1321-6.
Title: Evidence for cardiac atrophic remodeling in cancer-induced cachexia in mice.
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Journal: FEBS Lett. 2011 Nov 16;585(22):3560-8.
Title: MicroRNA 506 regulates expression of PPAR alpha in hydroxycamptothecin-resistant human colon cancer cells.
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Title: Cancer chemopreventive ability of conjugated linolenic acids.
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Journal: Am J Physiol Gastrointest Liver Physiol. 2012 Jan 1;302(1):G153-67.
Title: Immunomodulatory action of dietary fish oil and targeted deletion of intestinal epithelial cell PPARdelta in inflammation-induced colon carcinogenesis.
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Journal: PPAR Res. 2012;2012:269751.
Title: AS601245, an Anti-Inflammatory JNK Inhibitor, and Clofibrate Have a Synergistic Effect in Inducing Cell Responses and in Affecting the Gene Expression Profile in CaCo-2 Colon Cancer Cells.
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Journal: PPAR Res. 2012;2012:242498.
Title: The role of peroxisome proliferator-activated receptors in the esophageal, gastric, and colorectal cancer.
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Journal: PPAR Res. 2012;2012:876418.
Title: The role of peroxisome proliferator-activated receptors in colorectal cancer.
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Journal: J Biol Chem. 2012 Nov 30;287(49):41364-73.
Title: beta-Catenin and peroxisome proliferator-activated receptor-delta coordinate dynamic chromatin loops for the transcription of vascular endothelial growth factor A gene in colon cancer cells.
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Journal: Mol Nutr Food Res. 2013 Apr;57(4):686-97.
Title: Differential gene expression and methylation in the retinoid/PPARA pathway and of tumor suppressors may modify intestinal tumorigenesis induced by low folate in mice.
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Journal: Nutr Cancer. 2013;65(1):139-46.
Title: Trans fatty acids affect cellular viability of human intestinal Caco-2 cells and activate peroxisome proliferator-activated receptors.
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Journal: Exp Toxicol Pathol. 2013 Sep;65(6):919-24.
Title: Characterization of PPAR dual ligand MCC-555 in AOM-induced colorectal tumorigenesis.
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Journal: Cancer Sci. 2013 Jun;104(6):687-93.
Title: Novel MEK inhibitor trametinib and other retinoblastoma gene (RB)-reactivating agents enhance efficacy of 5-fluorouracil on human colon cancer cells.
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Journal: PLoS One. 2013 Apr 8;8(4):e60715.
Title: Knockdown of PPAR delta gene promotes the growth of colon cancer and reduces the sensitivity to bevacizumab in nude mice model.
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Journal: Asian Pac J Cancer Prev. 2013;14(3):1819-23.
Title: Analysis of key genes and pathways associated with colorectal cancer with microarray technology.
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Journal: Carcinogenesis. 2013 Nov;34(11):2580-6.
Title: The 5-aminosalicylic acid antineoplastic effect in the intestine is mediated by PPARgamma.
Author: Rousseaux, Christel|El-Jamal, Noura|Fumery, Mathurin|Dubuquoy, Caroline|Romano, Olivier|Chatelain, Denis|Langlois, Audrey|Bertin, Benjamin|Buob, David|Colombel, Jean Frederic|Cortot, Antoine|Desreumaux, Pierre|Dubuquoy, Laurent
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Journal: Mol Carcinog. 2014 Nov;53(11):926-37.
Title: PPARdelta deficiency disrupts hypoxia-mediated tumorigenic potential of colon cancer cells.
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Journal: Biochim Biophys Acta. 2014 Jun;1843(6):1225-36.
Title: Peroxisome proliferator-activated receptor gamma-mediated induction of microRNA-145 opposes tumor phenotype in colorectal cancer.
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Journal: J Natl Cancer Inst. 2014 Apr;106(4):dju052.
Title: Potentiation of colon cancer susceptibility in mice by colonic epithelial PPAR-delta/beta overexpression.
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Journal: Biomed Pharmacother. 2014 Jun;68(5):537-50.
Title: Piroxicam and c-phycocyanin prevent colon carcinogenesis by inhibition of membrane fluidity and canonical Wnt/beta-catenin signaling while up-regulating ligand dependent transcription factor PPARgamma.
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Journal: Biomed Res Int. 2014;2014:832025.
Title: Alterations in lipid mediated signaling and Wnt/ beta -catenin signaling in DMH induced colon cancer on supplementation of fish oil.
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Journal: PLoS One. 2014 Jul 18;9(7):e102758.
Title: Oxaliplatin neurotoxicity involves peroxisome alterations. PPARgamma agonism as preventive pharmacological approach.
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Journal: Anticancer Drugs. 2014 Oct;25(9):1016-27.
Title: Luteolin potentiates the sensitivity of colorectal cancer cell lines to oxaliplatin through the PPARgamma/OCTN2 pathway.
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Journal: Pharmacogenet Genomics. 2015 Jan;25(1):30-7.
Title: Genetic variants within obesity-related genes are associated with tumor recurrence in patients with stages II/III colon cancer.
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Journal: Biochem Biophys Res Commun. 2015 Apr 10;459(3):475-80.
Title: Voluntary exercise prevents colonic inflammation in high-fat diet-induced obese mice by up-regulating PPAR-gamma activity.
Author: Liu, Wei-Xin|Wang, Ting|Zhou, Feng|Wang, Ying|Xing, Jun-Wei|Zhang, Shen|Gu, Shou-Zhi|Sang, Li-Xuan|Dai, Cong|Wang, Hai-Lan
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Journal: FASEB J. 2015 Jun;29(6):2359-70.
Title: 15-Lipoxygenase-1 suppression of colitis-associated colon cancer through inhibition of the IL-6/STAT3 signaling pathway.
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Journal: Curr Pharm Des. 2015;21(21):2956-9.
Title: PPARdelta signaling regulates colorectal cancer.
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Journal: Oncol Res Treat. 2015;38(10):511-6.
Title: L-Carnitine Ameliorates Cancer Cachexia in Mice Partly via the Carnitine Palmitoyltransferase-Associated PPAR-gamma Signaling Pathway.
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Journal: Endocr J. 2015;62(12):1133-7.
Title: Effect of dapagliflozin on colon cancer cell [Rapid Communication].
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Journal: Oncol Lett. 2015 Sep;10(3):1259-1266.
Title: Peroxisome proliferator-activated receptor-gamma is downregulated in ulcerative colitis and is involved in experimental colitis-associated neoplasia.
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Journal: Int J Colorectal Dis. 2016 Feb;31(2):365-75.
Title: Peritumoral adipose tissue as a source of inflammatory and angiogenic factors in colorectal cancer.
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Journal: Mol Med Rep. 2016 Feb;13(2):1320-8.
Title: L-carnitine ameliorates the liver inflammatory response by regulating carnitine palmitoyltransferase I-dependent PPARgamma signaling.
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Journal: J Nat Prod. 2016 Jan 22;79(1):2-12.
Title: Amorfrutin C Induces Apoptosis and Inhibits Proliferation in Colon Cancer Cells through Targeting Mitochondria.
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Journal: Histopathology. 2016 Aug;69(2):268-75.
Title: Clinical relevance of cyclooxygenase 2 and peroxisome proliferator-activated receptor gamma in eyelid sebaceous gland carcinoma.
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Journal: Cancer Res. 2016 Feb 1;76(3):630-42.
Title: Systemic Chromosome Instability Resulted in Colonic Transcriptomic Changes in Metabolic, Proliferation, and Stem Cell Regulators in Sgo1-/+ Mice.
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Journal: Phytother Res. 2016 Jun;30(6):963-70.
Title: Palmitoylethanolamide Exerts Antiproliferative Effect and Downregulates VEGF Signaling in Caco-2 Human Colon Carcinoma Cell Line Through a Selective PPAR-alpha-Dependent Inhibition of Akt/mTOR Pathway.
Author: Sarnelli, Giovanni|Gigli, Stefano|Capoccia, Elena|Iuvone, Teresa|Cirillo, Carla|Seguella, Luisa|Nobile, Nicola|D'Alessandro, Alessandra|Pesce, Marcella|Steardo, Luca|Cuomo, Rosario|Esposito, Giuseppe
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Journal: Endocrine. 2016 Aug;53(2):443-52.
Title: SIRT1 prevents hyperuricemia via the PGC-1alpha/PPARgamma-ABCG2 pathway.
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Journal: Neurogastroenterol Motil. 2016 Dec;28(12):1765-1780.
Title: The gastrointestinal tract - a central organ of cannabinoid signaling in health and disease.
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Journal: Clin Cancer Res. 2016 Dec 1;22(23):5636-5641.
Title: Molecular Pathways: Dietary Regulation of Stemness and Tumor Initiation by the PPAR-delta Pathway.
Author: Beyaz, Semir|Yilmaz, Omer H
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Journal: Cell Metab. 2016 Nov 8;24(5):672-684.
Title: Tumor-Induced IL-6 Reprograms Host Metabolism to Suppress Anti-tumor Immunity.
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Journal: Oncotarget. 2017 Apr 4;8(14):22460-22476.
Title: HMGCS2 enhances invasion and metastasis via direct interaction with PPARalpha to activate Src signaling in colorectal cancer and oral cancer.
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Journal: Eur J Med Chem. 2017 Feb 15;127:379-397.
Title: New diphenylmethane derivatives as peroxisome proliferator-activated receptor alpha/gamma dual agonists endowed with anti-proliferative effects and mitochondrial activity.
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Journal: United European Gastroenterol J. 2017 Mar;5(2):218-226.
Title: A PPAR-gamma agonist protects from radiation-induced intestinal toxicity.
Author: Mangoni, Monica|Sottili, Mariangela|Gerini, Chiara|Desideri, Isacco|Bastida, Cinzia|Pallotta, Stefania|Castiglione, Francesca|Bonomo, Pierluigi|Meattini, Icro|Greto, Daniela|Cappelli, Sabrina|Di Brina, Lucia|Loi, Mauro|Biti, Giampaolo|Livi, Lorenzo
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Journal: Acta Sci Pol Technol Aliment. 2017 Jan-Mar;16(1):83-91.
Title: The genetic basis of obesity complications.
Author: Skrypnik, Katarzyna|Suliburska, Joanna|Skrypnik, Damian|Pilarski, Lukasz|Regula, Julita|Bogdanski, Pawel
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Journal: BMC Gastroenterol. 2017 Jun 7;17(1):73.
Title: Anti-fibrogenic effect of PPAR-gamma agonists in human intestinal myofibroblasts.
Author: Koo, Jun Bon|Nam, Myeong-Ok|Jung, Younshin|Yoo, Jongman|Kim, Duk Hwan|Kim, Gwangil|Shin, Sung Jae|Lee, Kee Myung|Hahm, Ki Baik|Kim, Jong Woo|Hong, Sung Pyo|Lee, Kwang Jae|Yoo, Jun Hwan
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Journal: Gene. 2017 Sep 5;627:484-490.
Title: Systemic analysis of different colorectal cancer cell lines and TCGA datasets identified IGF-1R/EGFR-PPAR-CASPASE axis as important indicator for radiotherapy sensitivity.
Author: Chen, Lin|Zhu, Zhe|Gao, Wei|Jiang, Qixin|Yu, Jiangming|Fu, Chuangang
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Journal: Mol Cancer Res. 2017 Nov;15(11):1481-1490.
Title: Chemoradiotherapy Resistance in Colorectal Cancer Cells is Mediated by Wnt/beta-catenin Signaling.
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Journal: Food Nutr Res. 2018 May 11;62. pii: 1384.
Title: Genistein and daidzein induce apoptosis of colon cancer cells by inhibiting the accumulation of lipid droplets.
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Journal: Food Chem Toxicol. 2018 Sep 6;121:237-245.
Title: Lyophilized acai pulp (Euterpe oleracea Mart) attenuates colitis-associated colon carcinogenesis while its main anthocyanin has the potential to affect the motility of colon cancer cells.
Author: Fragoso, Mariana F|Romualdo, Guilherme R|Vanderveer, Lisa A|Franco-Barraza, Janusz|Cukierman, Edna|Clapper, Margie L|Carvalho, Robson F|Barbisan, Luis F
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Journal: Mucosal Immunol. 2018 Oct 2. pii: 10.1038/s41385-018-0090-8.
Title: CLA-supplemented diet accelerates experimental colorectal cancer by inducing TGF-beta-producing macrophages and T cells.
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