Primary Site >> Liver Cancer

Gene >> PLK4

Journal: Oncodev Biol Med. 1981;2(3):165-77.
Title: Physiochemical and immunochemical characterization of gamma-glutamyl transpeptidase from yolk sak tumor and ascitic hepatoma (AH-66) cells.
Author: Yokosawa, N|Taniguchi, N|Tsukada, Y|Makita, A
PMID: 6117836
Journal: Nat Genet. 2005 Aug;37(8):883-8.
Title: Plk4 haploinsufficiency causes mitotic infidelity and carcinogenesis.
Author: Ko, Michael A|Rosario, Carla O|Hudson, John W|Kulkarni, Sarang|Pollett, Aaron|Dennis, James W|Swallow, Carol J
PMID: 16025114
Journal: Hepatology. 2010 Mar;51(3):857-68.
Title: Oncogenic and tumor suppressive roles of polo-like kinases in human hepatocellular carcinoma.
Author: Pellegrino, Rossella|Calvisi, Diego F|Ladu, Sara|Ehemann, Volker|Staniscia, Tommaso|Evert, Matthias|Dombrowski, Frank|Schirmacher, Peter|Longerich, Thomas
PMID: 20112253
Journal: Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):6888-93.
Title: Plk4 is required for cytokinesis and maintenance of chromosomal stability.
Author: Rosario, Carla O|Ko, Michael A|Haffani, Yosr Z|Gladdy, Rebecca A|Paderova, Jana|Pollett, Aaron|Squire, Jeremy A|Dennis, James W|Swallow, Carol J
PMID: 20348415
Journal: BMC Cancer. 2011 Feb 15;11:71.
Title: Aberrant methylation of Polo-like kinase CpG islands in Plk4 heterozygous mice.
Author: Ward, Alejandra|Morettin, Alan|Shum, David|Hudson, John W
PMID: 21324136
Journal: PLoS One. 2012;7(7):e41293.
Title: Downregulation of polo-like kinase 4 in hepatocellular carcinoma associates with poor prognosis.
Author: Liu, Lili|Zhang, Chris Zhiyi|Cai, Muyan|Fu, Jia|Chen, George Gong|Yun, Jingping
PMID: 22829937
Journal: PLoS One. 2014 Jan 31;9(1):e87918.
Title: p53-Dependent and cell specific epigenetic regulation of the polo-like kinases under oxidative stress.
Author: Ward, Alejandra|Hudson, John W
PMID: 24498222
Journal: Cell Death Dis. 2018 Oct 12;9(10):1045.
Title: MiR-126 negatively regulates PLK-4 to impact the development of hepatocellular carcinoma via ATR/CHEK1 pathway.
Author: Bao, Jie|Yu, Yan|Chen, Jianan|He, Yuting|Chen, Xiaolong|Ren, Zhigang|Xue, Chen|Liu, Liwen|Hu, Qiuyue|Li, Juan|Cui, Guangying|Sun, Ranran
PMID: 30315225