Primary Site >> Liver Cancer

Gene >> PLK4

  • 1981
  • 2005
  • 2010
  • 2011
  • 2012
  • 2014
  • 2018
Ref: Physiochemical and immunochemical characterization of gamma-glutamyl transpeptidase from yolk sak tumor and ascitic hepatoma (AH-66) cells.
PMID: 6117836
Ref: Plk4 haploinsufficiency causes mitotic infidelity and carcinogenesis.
PMID: 16025114
Ref: Oncogenic and tumor suppressive roles of polo-like kinases in human hepatocellular carcinoma.
PMID: 20112253
Ref: Plk4 is required for cytokinesis and maintenance of chromosomal stability.
PMID: 20348415
Ref: Aberrant methylation of Polo-like kinase CpG islands in Plk4 heterozygous mice.
PMID: 21324136
Ref: Downregulation of polo-like kinase 4 in hepatocellular carcinoma associates with poor prognosis.
PMID: 22829937
Ref: p53-Dependent and cell specific epigenetic regulation of the polo-like kinases under oxidative stress.
PMID: 24498222
Ref: MiR-126 negatively regulates PLK-4 to impact the development of hepatocellular carcinoma via ATR/CHEK1 pathway.
PMID: 30315225