Primary Site >> Liver Cancer
Gene >> PLK1
| 1. | |||||||||||
| Journal: | Oncogene. 2004 Aug 5;23(35):5901-11. | ||||||||||
| Title: | Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas. | ||||||||||
| Author: | Yamada, Shin-ichi|Ohira, Miki|Horie, Hiroshi|Ando, Kiyohiro|Takayasu, Hajime|Suzuki, Yutaka|Sugano, Sumio|Hirata, Takahiro|Goto, Takeshi|Matsunaga, Tadashi|Hiyama, Eiso|Hayashi, Yutaka|Ando, Hisami|Suita, Sachiyo|Kaneko, Michio|Sasaki, Fumiaki|Hashizume, | ||||||||||
| PMID: | 15221005 | ||||||||||
| 2. | |||||||||||
| Journal: | J Clin Invest. 2007 Jan;117(1):99-111. | ||||||||||
| Title: | A cell-penetrating ARF peptide inhibitor of FoxM1 in mouse hepatocellular carcinoma treatment. | ||||||||||
| Author: | Gusarova, Galina A|Wang, I-Ching|Major, Michael L|Kalinichenko, Vladimir V|Ackerson, Timothy|Petrovic, Vladimir|Costa, Robert H | ||||||||||
| PMID: | 17173139 | ||||||||||
| 3. | |||||||||||
| Journal: | Mol Cancer Ther. 2008 Sep;7(9):2904-12. | ||||||||||
| Title: | Administration of PLK-1 small interfering RNA with atelocollagen prevents the growth of liver metastases of lung cancer. | ||||||||||
| Author: | Kawata, Eri|Ashihara, Eishi|Kimura, Shinya|Takenaka, Kazumasa|Sato, Kiyoshi|Tanaka, Ruriko|Yokota, Asumi|Kamitsuji, Yuri|Takeuchi, Miki|Kuroda, Junya|Tanaka, Fumihiro|Yoshikawa, Toshikazu|Maekawa, Taira | ||||||||||
| PMID: | 18790771 | ||||||||||
| 4. | |||||||||||
| Journal: | Clin Cancer Res. 2008 Nov 1;14(21):6813-20. | ||||||||||
| Title: | Aberrant Polo-like kinase 1-Cdc25A pathway in metastatic hepatocellular carcinoma. | ||||||||||
| Author: | Wang, Xiao Qi|Zhu, Yong Qiang|Lui, Karen S|Cai, Qi|Lu, Ping|Poon, Ronnie T | ||||||||||
| PMID: | 18980975 | ||||||||||
| 5. | |||||||||||
| Journal: | Hepatology. 2009 Aug;50(2):414-23. | ||||||||||
| Title: | Polo-like kinase 1 inhibition suppresses hepatitis B virus X protein-induced transformation in an in vitro model of liver cancer progression. | ||||||||||
| Author: | Studach, Leo L|Rakotomalala, Lova|Wang, Wen-Horng|Hullinger, Ronald L|Cairo, Stefano|Buendia, Marie-Annick|Andrisani, Ourania M | ||||||||||
| PMID: | 19472310 | ||||||||||
| 6. | |||||||||||
| Journal: | Oncogene. 2009 Oct 15;28(41):3631-41. | ||||||||||
| Title: | Plk1 regulates liver tumor cell death by phosphorylation of TAp63. | ||||||||||
| Author: | Komatsu, S|Takenobu, H|Ozaki, T|Ando, K|Koida, N|Suenaga, Y|Ichikawa, T|Hishiki, T|Chiba, T|Iwama, A|Yoshida, H|Ohnuma, N|Nakagawara, A|Kamijo, T | ||||||||||
| PMID: | 19668228 | ||||||||||
| 7. | |||||||||||
| Journal: | Hepatology. 2010 Mar;51(3):857-68. | ||||||||||
| Title: | Oncogenic and tumor suppressive roles of polo-like kinases in human hepatocellular carcinoma. | ||||||||||
| Author: | Pellegrino, Rossella|Calvisi, Diego F|Ladu, Sara|Ehemann, Volker|Staniscia, Tommaso|Evert, Matthias|Dombrowski, Frank|Schirmacher, Peter|Longerich, Thomas | ||||||||||
| PMID: | 20112253 | ||||||||||
| 8. | |||||||||||
| Journal: | Cancer Biol Ther. 2011 Feb 15;11(4):401-9. Epub 2011 Feb 15. | ||||||||||
| Title: | Intravenous liposomal delivery of the short hairpin RNAs against Plk1 controls the growth of established human hepatocellular carcinoma. | ||||||||||
| Author: | Deng, Hongxin|Jiang, Qingyuan|Yang, Yang|Zhang, Shuang|Ma, Yongping|Xie, Gang|Chen, Xiang|Qian, Zhiyong|Wen, Yanjun|Li, Jiong|Yang, Jinliang|Chen, Lijuan|Zhao, Xia|Wei, Yuquan | ||||||||||
| PMID: | 21150280 | ||||||||||
| 9. | |||||||||||
| Journal: | BMC Cancer. 2011 Feb 15;11:71. | ||||||||||
| Title: | Aberrant methylation of Polo-like kinase CpG islands in Plk4 heterozygous mice. | ||||||||||
| Author: | Ward, Alejandra|Morettin, Alan|Shum, David|Hudson, John W | ||||||||||
| PMID: | 21324136 | ||||||||||
| 10. | |||||||||||
| Journal: | Toxicol Appl Pharmacol. 2011 May 1;252(3):307-17. | ||||||||||
| Title: | Proteomic profiling revealed the functional networks associated with mitotic catastrophe of HepG2 hepatoma cells induced by 6-bromine-5-hydroxy-4-methoxybenzaldehyde. | ||||||||||
| Author: | Zhang, Bo|Huang, Bo|Guan, Hua|Zhang, Shi-Meng|Xu, Qin-Zhi|He, Xing-Peng|Liu, Xiao-Dan|Wang, Yu|Shang, Zeng-Fu|Zhou, Ping-Kun | ||||||||||
| PMID: | 21419150 | ||||||||||
| 11. | |||||||||||
| Journal: | J Control Release. 2011 Dec 10;156(2):203-11. | ||||||||||
| Title: | Systemic delivery of siRNA with cationic lipid assisted PEG-PLA nanoparticles for cancer therapy. | ||||||||||
| Author: | Yang, Xian-Zhu|Dou, Shuang|Sun, Tian-Meng|Mao, Cheng-Qiong|Wang, Hong-Xia|Wang, Jun | ||||||||||
| PMID: | 21839126 | ||||||||||
| 12. | |||||||||||
| Journal: | Oncogene. 2012 Oct 18;31(42):4517-26. | ||||||||||
| Title: | Sequential analysis of multistage hepatocarcinogenesis reveals that miR-100 and PLK1 dysregulation is an early event maintained along tumor progression. | ||||||||||
| Author: | Petrelli, A|Perra, A|Schernhuber, K|Cargnelutti, M|Salvi, A|Migliore, C|Ghiso, E|Benetti, A|Barlati, S|Ledda-Columbano, G M|Portolani, N|De Petro, G|Columbano, A|Giordano, S | ||||||||||
| PMID: | 22249248 | ||||||||||
| 13. | |||||||||||
| Journal: | Mol Cell Biochem. 2012 Jun;365(1-2):99-108. | ||||||||||
| Title: | Study on the effect of IRE1a on cell growth and apoptosis via modulation PLK1 in ER stress response. | ||||||||||
| Author: | Li, Xiangzhu|Zhu, Huifang|Huang, Huizhe|Jiang, Rong|Zhao, Wenjun|Liu, Yanna|Zhou, Jinghua|Guo, Feng-Jin | ||||||||||
| PMID: | 22314839 | ||||||||||
| 14. | |||||||||||
| Journal: | Hepatology. 2012 Oct;56(4):1240-51. | ||||||||||
| Title: | Subset of Suz12/PRC2 target genes is activated during hepatitis B virus replication and liver carcinogenesis associated with HBV X protein. | ||||||||||
| Author: | Studach, Leo L|Menne, Stephan|Cairo, Stefano|Buendia, Marie Annick|Hullinger, Ronald L|Lefrancois, Lydie|Merle, Philippe|Andrisani, Ourania M | ||||||||||
| PMID: | 22505317 | ||||||||||
| 15. | |||||||||||
| Journal: | World J Gastroenterol. 2012 Jul 21;18(27):3527-36. | ||||||||||
| Title: | Polo-like kinase 1, a new therapeutic target in hepatocellular carcinoma. | ||||||||||
| Author: | Mok, Wei Chuen|Wasser, Shanthi|Tan, Theresa|Lim, Seng Gee | ||||||||||
| PMID: | 22826617 | ||||||||||
| 16. | |||||||||||
| Journal: | Mol Cell Biochem. 2013 Nov;383(1-2):49-58. | ||||||||||
| Title: | Downregulation of microRNA-100 correlates with tumor progression and poor prognosis in hepatocellular carcinoma. | ||||||||||
| Author: | Chen, Ping|Zhao, Xia|Ma, Liang | ||||||||||
| PMID: | 23842624 | ||||||||||
| 17. | |||||||||||
| Journal: | Nanomedicine (Lond). 2014 Apr;9(4):407-20. | ||||||||||
| Title: | Escheriosome-mediated cytosolic delivery of PLK1-specific siRNA: potential in treatment of liver cancer in BALB/c mice. | ||||||||||
| Author: | Chauhan, Arun|Zubair, Swaleha|Nadeem, Ahmad|Ansari, Sajid Ali|Ansari, Mohammad Yunus|Mohammad, Owais | ||||||||||
| PMID: | 24910873 | ||||||||||
| 18. | |||||||||||
| Journal: | Mol Ther. 2014 Jan;22(1):92-101. | ||||||||||
| Title: | Knockdown of beta-catenin with dicer-substrate siRNAs reduces liver tumor burden in vivo. | ||||||||||
| Author: | Dudek, Henryk|Wong, Darren H|Arvan, Rokhand|Shah, Anee|Wortham, Kathleen|Ying, Bo|Diwanji, Rohan|Zhou, Wei|Holmes, Benjamin|Yang, Hailin|Cyr, Wendy A|Zhou, Yi|Shah, Aalok|Farkiwala, Ruchir|Lee, Michael|Li, Yiting|Rettig, Garrett R|Collingwood, Michael A|B | ||||||||||
| PMID: | 24089139 | ||||||||||
| 19. | |||||||||||
| Journal: | PLoS One. 2014 Jan 31;9(1):e87918. | ||||||||||
| Title: | p53-Dependent and cell specific epigenetic regulation of the polo-like kinases under oxidative stress. | ||||||||||
| Author: | Ward, Alejandra|Hudson, John W | ||||||||||
| PMID: | 24498222 | ||||||||||
| 20. | |||||||||||
| Journal: | Cancer Res. 2015 Jun 1;75(11):2363-74. | ||||||||||
| Title: | PLK1 and HOTAIR Accelerate Proteasomal Degradation of SUZ12 and ZNF198 during Hepatitis B Virus-Induced Liver Carcinogenesis. | ||||||||||
| Author: | Zhang, Hao|Diab, Ahmed|Fan, Huitao|Mani, Saravana Kumar Kailasam|Hullinger, Ronald|Merle, Philippe|Andrisani, Ourania | ||||||||||
| PMID: | 25855382 | ||||||||||
| 21. | |||||||||||
| Journal: | Oncol Rep. 2015 Aug;34(2):823-32. | ||||||||||
| Title: | USP39 promotes the growth of human hepatocellular carcinoma in vitro and in vivo. | ||||||||||
| Author: | Yuan, Xianwen|Sun, Xitai|Shi, Xiaolei|Jiang, Chunping|Yu, Decai|Zhang, Weiwei|Guan, Wenxian|Zhou, Jianxin|Wu, Yafu|Qiu, Yudong|Ding, Yitao | ||||||||||
| PMID: | 26081192 | ||||||||||
| 22. | |||||||||||
| Journal: | Chem Biol Interact. 2015 Dec 5;242:107-22. | ||||||||||
| Title: | Novel carbocyclic curcumin analog CUR3d modulates genes involved in multiple apoptosis pathways in human hepatocellular carcinoma cells. | ||||||||||
| Author: | Bhullar, Khushwant S|Jha, Amitabh|Rupasinghe, H P Vasantha | ||||||||||
| PMID: | 26409325 | ||||||||||
| 23. | |||||||||||
| Journal: | Oncotarget. 2016 Mar 1;7(9):9832-43. | ||||||||||
| Title: | RB/PLK1-dependent induced pathway by SLAMF3 expression inhibits mitosis and control hepatocarcinoma cell proliferation. | ||||||||||
| Author: | Bouhlal, Hicham|Ouled-Haddou, Hakim|Debuysscher, Veronique|Singh, Amrathlal Rabbind|Ossart, Christele|Reignier, Aline|Hocini, Hakim|Fouquet, Gregory|Al Baghami, Mohammed|Eugenio, Melanie Simoes|Nguyen-Khac, Eric|Regimbeau, Jean-Marc|Marcq, Ingrid | ||||||||||
| PMID: | 26799423 | ||||||||||
| 24. | |||||||||||
| Journal: | Oncotarget. 2016 Feb 23;7(8):9448-61. | ||||||||||
| Title: | HBV polymerase overexpression due to large core gene deletion enhances hepatoma cell growth by binding inhibition of microRNA-100. | ||||||||||
| Author: | Huang, Ya-Hui|Tseng, Ying-Hsin|Lin, Wey-Ran|Hung, George|Chen, Tse-Ching|Wang, Tong-Hong|Lee, Wei-Chen|Yeh, Chau-Ting | ||||||||||
| PMID: | 26824500 | ||||||||||
| 25. | |||||||||||
| Journal: | Genetics. 2016 Oct;204(2):807-819. | ||||||||||
| Title: | A Synthetic Dosage Lethal Genetic Interaction Between CKS1B and PLK1 Is Conserved in Yeast and Human Cancer Cells. | ||||||||||
| Author: | Reid, Robert J D|Du, Xing|Sunjevaric, Ivana|Rayannavar, Vinayak|Dittmar, John|Bryant, Eric|Maurer, Matthew|Rothstein, Rodney | ||||||||||
| PMID: | 27558135 | ||||||||||
| 26. | |||||||||||
| Journal: | Am J Cancer Res. 2016 Nov 1;6(11):2476-2488. eCollection 2016. | ||||||||||
| Title: | Volasertib suppresses the growth of human hepatocellular carcinoma in vitro and in vivo. | ||||||||||
| Author: | Zheng, Di-Wei|Xue, You-Qiu|Li, Yong|Di, Jin-Ming|Qiu, Jian-Ge|Zhang, Wen-Ji|Jiang, Qi-Wei|Yang, Yang|Chen, Yao|Wei, Meng-Ning|Huang, Jia-Rong|Wang, Kun|Wei, Xing|Shi, Zhi | ||||||||||
| PMID: | 27904765 | ||||||||||
| 27. | |||||||||||
| Journal: | Br J Cancer. 2017 Apr 11;116(8):1027-1036. | ||||||||||
| Title: | Dasatinib synergises with irinotecan to suppress hepatocellular carcinoma via inhibiting the protein synthesis of PLK1. | ||||||||||
| Author: | Xu, Li|Zhu, Yuanrun|Shao, Jinjin|Chen, Min|Yan, Hao|Li, Guanqun|Zhu, Yi|Xu, Zhifei|Yang, Bo|Luo, Peihua|He, Qiaojun | ||||||||||
| PMID: | 28267710 | ||||||||||
| 28. | |||||||||||
| Journal: | Cancer Genet. 2017 Oct;216-217:37-51. | ||||||||||
| Title: | Gene expression profiling, pathway analysis and subtype classification reveal molecular heterogeneity in hepatocellular carcinoma and suggest subtype specific therapeutic targets. | ||||||||||
| Author: | Agarwal, Rahul|Narayan, Jitendra|Bhattacharyya, Amitava|Saraswat, Mayank|Tomar, Anil Kumar | ||||||||||
| PMID: | 29025594 | ||||||||||
| 29. | |||||||||||
| Journal: | Cancer Cell. 2017 Jul 10;32(1):57-70.e3. | ||||||||||
| Title: | Common Molecular Subtypes Among Asian Hepatocellular Carcinoma and Cholangiocarcinoma. | ||||||||||
| Author: | Chaisaingmongkol, Jittiporn|Budhu, Anuradha|Dang, Hien|Rabibhadana, Siritida|Pupacdi, Benjarath|Kwon, So Mee|Forgues, Marshonna|Pomyen, Yotsawat|Bhudhisawasdi, Vajarabhongsa|Lertprasertsuke, Nirush|Chotirosniramit, Anon|Pairojkul, Chawalit|Auewarakul, Chi | ||||||||||
| PMID: | 28648284 | ||||||||||
| 30. | |||||||||||
| Journal: | Appl Immunohistochem Mol Morphol. 2017 Feb 9. | ||||||||||
| Title: | A Brief Report of Immunohistochemical Markers to Identify Aggressive Hepatoblastoma. | ||||||||||
| Author: | Singh, Vivekanand|Manalang, Michelle|Singh, Meenal|Apte, Udayan | ||||||||||
| PMID: | 28187036 | ||||||||||
| 31. | |||||||||||
| Journal: | Mol Med Rep. 2018 Jun;17(6):8153-8160. | ||||||||||
| Title: | Key signaling pathways, genes and transcription factors associated with hepatocellular carcinoma. | ||||||||||
| Author: | Wang, Jingcheng|Tian, Yang|Chen, Hui|Li, Hui|Zheng, Shusen | ||||||||||
| PMID: | 29658607 | ||||||||||
| 32. | |||||||||||
| Journal: | Med Sci Monit. 2018 May 5;24:2786-2808. | ||||||||||
| Title: | Expression of the Long Intergenic Non-Protein Coding RNA 665 (LINC00665) Gene and the Cell Cycle in Hepatocellular Carcinoma Using The Cancer Genome Atlas, the Gene Expression Omnibus, and Quantitative Real-Time Polymerase Chain Reaction. | ||||||||||
| Author: | Wen, Dong-Yue|Lin, Peng|Pang, Yu-Yan|Chen, Gang|He, Yun|Dang, Yi-Wu|Yang, Hong | ||||||||||
| PMID: | 29728556 | ||||||||||
| 33. | |||||||||||
| Journal: | Cancer Biomark. 2018;22(3):511-521. | ||||||||||
| Title: | Screening and function analysis of hub genes and pathways in hepatocellular carcinoma via bioinformatics approaches. | ||||||||||
| Author: | Zhang, Liang|Huang, Yi|Ling, Junjun|Zhuo, Wenlei|Yu, Zhen|Shao, Mengmeng|Luo, Yunbo|Zhu, Yi | ||||||||||
| PMID: | 29843214 | ||||||||||
| 34. | |||||||||||
| Journal: | J Pathol. 2018 Aug;245(4):502-513. | ||||||||||
| Title: | Intrahepatic hepatitis B virus large surface antigen induces hepatocyte hyperploidy via failure of cytokinesis. | ||||||||||
| Author: | Li, Tian-Neng|Wu, Yi-Ju|Tsai, Hung-Wen|Sun, Cheng-Pu|Wu, Yi-Hsuan|Wu, Hui-Lin|Pei, Yi-Ning|Lu, Kuan-Ying|Yen, Tim Ting-Chung|Chang, Chien-Wen|Chan, Hong-Lin|Tao, Mi-Hua|Liou, Jun-Yang|Chang, Margaret Dah-Tsyr|Su, Ih-Jen|Wang, Lily Hui-Ching | ||||||||||
| PMID: | 29862509 | ||||||||||
| 35. | |||||||||||
| Journal: | PeerJ. 2018 Jul 18;6:e5203. | ||||||||||
| Title: | Microarray gene expression profiling in colorectal (HCT116) and hepatocellular (HepG2) carcinoma cell lines treated with Melicope ptelefolia leaf extract reveals transcriptome profiles exhibiting anticancer activity. | ||||||||||
| Author: | Kabir, Mohammad Faujul|Mohd Ali, Johari|Haji Hashim, Onn | ||||||||||
| PMID: | 30042885 | ||||||||||
| 36. | |||||||||||
| Journal: | J Pathol. 2018 Sep 23. | ||||||||||
| Title: | Hepatitis B virus large surface protein is priming for hepatocellular carcinoma development via induction of cytokinesis failure. | ||||||||||
| Author: | Musa, Julian|Li, Jing|Grunewald, Thomas G P | ||||||||||
| PMID: | 30246253 | ||||||||||
| 37. | |||||||||||
| Journal: | Cell Death Dis. 2018 Oct 12;9(10):1045. | ||||||||||
| Title: | MiR-126 negatively regulates PLK-4 to impact the development of hepatocellular carcinoma via ATR/CHEK1 pathway. | ||||||||||
| Author: | Bao, Jie|Yu, Yan|Chen, Jianan|He, Yuting|Chen, Xiaolong|Ren, Zhigang|Xue, Chen|Liu, Liwen|Hu, Qiuyue|Li, Juan|Cui, Guangying|Sun, Ranran | ||||||||||
| PMID: | 30315225 | ||||||||||