Primary Site >> Liver Cancer
Gene >> PLK1
|
|
|
|
|
|
|
|
|
|
|
|
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Ref: Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas. PMID: 15221005 |
Ref: A cell-penetrating ARF peptide inhibitor of FoxM1 in mouse hepatocellular carcinoma treatment. PMID: 17173139 |
Ref: Administration of PLK-1 small interfering RNA with atelocollagen prevents the growth of liver metastases of lung cancer. PMID: 18790771 Ref: Aberrant Polo-like kinase 1-Cdc25A pathway in metastatic hepatocellular carcinoma. PMID: 18980975 |
Ref: Polo-like kinase 1 inhibition suppresses hepatitis B virus X protein-induced transformation in an in vitro model of liver cancer progression. PMID: 19472310 Ref: Plk1 regulates liver tumor cell death by phosphorylation of TAp63. PMID: 19668228 |
Ref: Oncogenic and tumor suppressive roles of polo-like kinases in human hepatocellular carcinoma. PMID: 20112253 |
Ref: Intravenous liposomal delivery of the short hairpin RNAs against Plk1 controls the growth of established human hepatocellular carcinoma. PMID: 21150280 Ref: Aberrant methylation of Polo-like kinase CpG islands in Plk4 heterozygous mice. PMID: 21324136 Ref: Proteomic profiling revealed the functional networks associated with mitotic catastrophe of HepG2 hepatoma cells induced by 6-bromine-5-hydroxy-4-methoxybenzaldehyde. PMID: 21419150 Ref: Systemic delivery of siRNA with cationic lipid assisted PEG-PLA nanoparticles for cancer therapy. PMID: 21839126 |
Ref: Sequential analysis of multistage hepatocarcinogenesis reveals that miR-100 and PLK1 dysregulation is an early event maintained along tumor progression. PMID: 22249248 Ref: Study on the effect of IRE1a on cell growth and apoptosis via modulation PLK1 in ER stress response. PMID: 22314839 Ref: Subset of Suz12/PRC2 target genes is activated during hepatitis B virus replication and liver carcinogenesis associated with HBV X protein. PMID: 22505317 Ref: Polo-like kinase 1, a new therapeutic target in hepatocellular carcinoma. PMID: 22826617 |
Ref: Downregulation of microRNA-100 correlates with tumor progression and poor prognosis in hepatocellular carcinoma. PMID: 23842624 |
Ref: Knockdown of beta-catenin with dicer-substrate siRNAs reduces liver tumor burden in vivo. PMID: 24089139 Ref: p53-Dependent and cell specific epigenetic regulation of the polo-like kinases under oxidative stress. PMID: 24498222 Ref: Escheriosome-mediated cytosolic delivery of PLK1-specific siRNA: potential in treatment of liver cancer in BALB/c mice. PMID: 24910873 |
Ref: PLK1 and HOTAIR Accelerate Proteasomal Degradation of SUZ12 and ZNF198 during Hepatitis B Virus-Induced Liver Carcinogenesis. PMID: 25855382 Ref: USP39 promotes the growth of human hepatocellular carcinoma in vitro and in vivo. PMID: 26081192 Ref: Novel carbocyclic curcumin analog CUR3d modulates genes involved in multiple apoptosis pathways in human hepatocellular carcinoma cells. PMID: 26409325 |
Ref: RB/PLK1-dependent induced pathway by SLAMF3 expression inhibits mitosis and control hepatocarcinoma cell proliferation. PMID: 26799423 Ref: HBV polymerase overexpression due to large core gene deletion enhances hepatoma cell growth by binding inhibition of microRNA-100. PMID: 26824500 Ref: A Synthetic Dosage Lethal Genetic Interaction Between CKS1B and PLK1 Is Conserved in Yeast and Human Cancer Cells. PMID: 27558135 Ref: Volasertib suppresses the growth of human hepatocellular carcinoma in vitro and in vivo. PMID: 27904765 |
Ref: A Brief Report of Immunohistochemical Markers to Identify Aggressive Hepatoblastoma. PMID: 28187036 Ref: Dasatinib synergises with irinotecan to suppress hepatocellular carcinoma via inhibiting the protein synthesis of PLK1. PMID: 28267710 Ref: Common Molecular Subtypes Among Asian Hepatocellular Carcinoma and Cholangiocarcinoma. PMID: 28648284 Ref: Gene expression profiling, pathway analysis and subtype classification reveal molecular heterogeneity in hepatocellular carcinoma and suggest subtype specific therapeutic targets. PMID: 29025594 |
Ref: Key signaling pathways, genes and transcription factors associated with hepatocellular carcinoma. PMID: 29658607 Ref: Expression of the Long Intergenic Non-Protein Coding RNA 665 (LINC00665) Gene and the Cell Cycle in Hepatocellular Carcinoma Using The Cancer Genome Atlas, the Gene Expression Omnibus, and Quantitative Real-Time Polymerase Chain Reaction. PMID: 29728556 Ref: Screening and function analysis of hub genes and pathways in hepatocellular carcinoma via bioinformatics approaches. PMID: 29843214 Ref: Intrahepatic hepatitis B virus large surface antigen induces hepatocyte hyperploidy via failure of cytokinesis. PMID: 29862509 Ref: Microarray gene expression profiling in colorectal (HCT116) and hepatocellular (HepG2) carcinoma cell lines treated with Melicope ptelefolia leaf extract reveals transcriptome profiles exhibiting anticancer activity. PMID: 30042885 Ref: Hepatitis B virus large surface protein is priming for hepatocellular carcinoma development via induction of cytokinesis failure. PMID: 30246253 Ref: MiR-126 negatively regulates PLK-4 to impact the development of hepatocellular carcinoma via ATR/CHEK1 pathway. PMID: 30315225 |