Primary Site >> Colorectal Cancer

Gene >> PLCG1

Journal: Cancer Biochem Biophys. 1993 Sep;13(4):265-78.
Title: Expression of a 118 Kd protein in colon carcinoma cells that is immunologically related to PLC-gamma 1 and is augmented by serum-free conditions.
Author: Fry, D W|Ambroso, L A
PMID: 8521376
Journal: Cancer. 1994 Jan 1;73(1):36-41.
Title: Elevated content of phospholipase C-gamma 1 in colorectal cancer tissues.
Author: Noh, D Y|Lee, Y H|Kim, S S|Kim, Y I|Ryu, S H|Suh, P G|Park, J G
PMID: 8275435
Journal: J Biol Chem. 1995 Jul 7;270(27):16378-84.
Title: Overexpression of phospholipase C-gamma 1 in colorectal carcinomas is associated with overexpression of factors that bind its promoter.
Author: Lee, S J|Lee, S D|Park, J G|Kim, C M|Ryu, S H|Suh, P G
PMID: 7608208
Journal: Mol Carcinog. 1995 Mar;12(3):146-52.
Title: Expression of phospholipases gamma 1, beta 1, and delta 1 in primary human colon carcinomas and colon carcinoma cell lines.
Author: Nomoto, K|Tomita, N|Miyake, M|Xhu, D B|LoGerfo, P R|Weinstein, I B
PMID: 7893368
Journal: Cancer Res. 1997 Dec 15;57(24):5465-8.
Title: Overexpression of phospholipase C-gamma1 in rat 3Y1 fibroblast cells leads to malignant transformation.
Author: Chang, J S|Noh, D Y|Park, I A|Kim, M J|Song, H|Ryu, S H|Suh, P G
PMID: 9407951
Journal: Life Sci. 2005 Oct 14;77(22):2794-803.
Title: NF-kappaB and Hsp70 are involved in the phospholipase Cgamma1 signaling pathway in colorectal cancer cells.
Author: Li, Xiumei|Hua, Liang|Deng, Fan|Bai, Xiaochun|Zeng, Weisen|Lu, Di|Su, Yongchun|Luo, Shenqiu
PMID: 15996687
Journal: Mol Cancer Ther. 2005 Aug;4(8):1198-204.
Title: Validation of in vivo pharmacodynamic activity of a novel PDGF receptor tyrosine kinase inhibitor using immunohistochemistry and quantitative image analysis.
Author: D'Andrea, Michael R|Mei, Jay M|Tuman, Robert W|Galemmo, Robert A|Johnson, Dana L
PMID: 16093435
Journal: Exp Cell Res. 2008 Feb 1;314(3):530-42. Epub 2007 Nov 12.
Title: Autotaxin and lysophosphatidic acid stimulate intestinal cell motility by redistribution of the actin modifying protein villin to the developing lamellipodia.
Author: Khurana, Seema|Tomar, Alok|George, Sudeep P|Wang, Yaohong|Siddiqui, Mohammad Rizwan|Guo, Huazhang|Tigyi, Gabor|Mathew, Sijo
PMID: 18054784
Journal: Genes Chromosomes Cancer. 2009 Nov;48(11):953-62.
Title: Integrative approach for prioritizing cancer genes in sporadic colon cancer.
Author: Reid, James F|Gariboldi, Manuela|Sokolova, Viktorija|Capobianco, Patrizia|Lampis, Andrea|Perrone, Federica|Signoroni, Stefano|Costa, Aurora|Leo, Ermanno|Pilotti, Silvana|Pierotti, Marco A
PMID: 19672874
Journal: BMC Cancer. 2009 Jan 12;9:12.
Title: Paxillin-Y118 phosphorylation contributes to the control of Src-induced anchorage-independent growth by FAK and adhesion.
Author: Sachdev, Sanjay|Bu, Yahao|Gelman, Irwin H
PMID: 19138410
Journal: Mol Biol Cell. 2010 Jul 1;21(13):2338-54.
Title: A G{alpha}i-GIV molecular complex binds epidermal growth factor receptor and determines whether cells migrate or proliferate.
Author: Ghosh, Pradipta|Beas, Anthony O|Bornheimer, Scott J|Garcia-Marcos, Mikel|Forry, Erin P|Johannson, Carola|Ear, Jason|Jung, Barbara H|Cabrera, Betty|Carethers, John M|Farquhar, Marilyn G
PMID: 20462955
Journal: Cell Oncol (Dordr). 2011 Feb;34(1):11-21.
Title: Downregulation of erythropoietin receptor by overexpression of phospholipase C-gamma 1 is critical for decrease on focal adhesion in transformed cells.
Author: Kang, Jin Ku|Chang, Chang-Hyun|Nam, Hyo Jung|Kim, Sung-Kuk|Ahn, Keun Jae|Seok, Heon|Park, Sang Joon|Kang, Yoon Joong|Jo, Young Suk|Shong, Minho|Kim, Ho
PMID: 21360263
Journal: Mol Cancer Res. 2011 Oct;9(10):1418-28.
Title: Cross-talk between phospho-STAT3 and PLCgamma1 plays a critical role in colorectal tumorigenesis.
Author: Zhang, Peng|Zhao, Yiqing|Zhu, Xiaofeng|Sedwick, David|Zhang, Xiaodong|Wang, Zhenghe
PMID: 21840932
Journal: Cell Death Dis. 2012 Oct 11;3:e406.
Title: A novel angiogenesis inhibitor impairs lovo cell survival via targeting against human VEGFR and its signaling pathway of phosphorylation.
Author: Zhang, Y M|Dai, B L|Zheng, L|Zhan, Y Z|Zhang, J|Smith, W W|Wang, X L|Chen, Y N|He, L C
PMID: 23059825
Journal: Phytomedicine. 2015 Jan 15;22(1):103-10.
Title: Raddeanin A, a triterpenoid saponin isolated from Anemone raddeana, suppresses the angiogenesis and growth of human colorectal tumor by inhibiting VEGFR2 signaling.
Author: Guan, Ying-Yun|Liu, Hai-Jun|Luan, Xin|Xu, Jian-Rong|Lu, Qin|Liu, Ya-Rong|Gao, Yun-Ge|Zhao, Mei|Chen, Hong-Zhuan|Fang, Chao
PMID: 25636878
Journal: Mediators Inflamm. 2016;2016:6189590.
Title: Fermented Herbal Formulas KIOM-MA128 Ameliorate IL-6-Induced Intestinal Barrier Dysfunction in Colon Cancer Cell Line.
Author: Park, Kwang Il|Kim, Dong Gun|Lee, Bo Hyoung|Ma, Jin Yeul
PMID: 27980357
Journal: Sci Rep. 2017 Oct 24;7(1):13912.
Title: Phosphoinositide-specific phospholipase Cgamma1 inhibition induces autophagy in human colon cancer and hepatocellular carcinoma cells.
Author: Dai, Lianzhi|Chen, Xiaolei|Lu, Xiaohong|Wang, Fen|Zhan, Yanyan|Song, Gang|Hu, Tianhui|Xia, Chun|Zhang, Bing
PMID: 29066806
Journal: Int J Mol Med. 2018 Jul;42(1):368-380.
Title: Inflammatory genes are novel prognostic biomarkers for colorectal cancer.
Author: Jiang, Hao|Dong, Li|Gong, Fangyan|Gu, Yuping|Zhang, Henghun|Fan, Dong|Sun, Zhiguo
PMID: 29693170
Journal: EMBO Rep. 2018 Sep 17. pii: embr.201846250.
Title: Netrin-1/DCC-mediated PLCgamma1 activation is required for axon guidance and brain structure development.
Author: Kang, Du-Seock|Yang, Yong Ryoul|Lee, Cheol|Park, BumWoo|Park, Kwang Il|Seo, Jeong Kon|Seo, Young Kyo|Cho, HyungJoon|Lucio, Cocco|Suh, Pann-Ghill
PMID: 30224412