Primary Site >> Colorectal Cancer
Gene >> PLCG1
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Ref: Expression of a 118 Kd protein in colon carcinoma cells that is immunologically related to PLC-gamma 1 and is augmented by serum-free conditions. PMID: 8521376 |
Ref: Elevated content of phospholipase C-gamma 1 in colorectal cancer tissues. PMID: 8275435 |
Ref: Overexpression of phospholipase C-gamma 1 in colorectal carcinomas is associated with overexpression of factors that bind its promoter. PMID: 7608208 Ref: Expression of phospholipases gamma 1, beta 1, and delta 1 in primary human colon carcinomas and colon carcinoma cell lines. PMID: 7893368 |
Ref: Overexpression of phospholipase C-gamma1 in rat 3Y1 fibroblast cells leads to malignant transformation. PMID: 9407951 |
Ref: NF-kappaB and Hsp70 are involved in the phospholipase Cgamma1 signaling pathway in colorectal cancer cells. PMID: 15996687 Ref: Validation of in vivo pharmacodynamic activity of a novel PDGF receptor tyrosine kinase inhibitor using immunohistochemistry and quantitative image analysis. PMID: 16093435 |
Ref: Autotaxin and lysophosphatidic acid stimulate intestinal cell motility by redistribution of the actin modifying protein villin to the developing lamellipodia. PMID: 18054784 |
Ref: Paxillin-Y118 phosphorylation contributes to the control of Src-induced anchorage-independent growth by FAK and adhesion. PMID: 19138410 Ref: Integrative approach for prioritizing cancer genes in sporadic colon cancer. PMID: 19672874 |
Ref: A G{alpha}i-GIV molecular complex binds epidermal growth factor receptor and determines whether cells migrate or proliferate. PMID: 20462955 |
Ref: Downregulation of erythropoietin receptor by overexpression of phospholipase C-gamma 1 is critical for decrease on focal adhesion in transformed cells. PMID: 21360263 Ref: Cross-talk between phospho-STAT3 and PLCgamma1 plays a critical role in colorectal tumorigenesis. PMID: 21840932 |
Ref: A novel angiogenesis inhibitor impairs lovo cell survival via targeting against human VEGFR and its signaling pathway of phosphorylation. PMID: 23059825 |
Ref: Raddeanin A, a triterpenoid saponin isolated from Anemone raddeana, suppresses the angiogenesis and growth of human colorectal tumor by inhibiting VEGFR2 signaling. PMID: 25636878 |
Ref: Fermented Herbal Formulas KIOM-MA128 Ameliorate IL-6-Induced Intestinal Barrier Dysfunction in Colon Cancer Cell Line. PMID: 27980357 |
Ref: Phosphoinositide-specific phospholipase Cgamma1 inhibition induces autophagy in human colon cancer and hepatocellular carcinoma cells. PMID: 29066806 |
Ref: Inflammatory genes are novel prognostic biomarkers for colorectal cancer. PMID: 29693170 Ref: Netrin-1/DCC-mediated PLCgamma1 activation is required for axon guidance and brain structure development. PMID: 30224412 |